Recent Patents on Anti-Cancer Drug Discovery

Papers
(The median citation count of Recent Patents on Anti-Cancer Drug Discovery is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Application of Nano Drug Delivery System (NDDS) in Cancer Therapy: A Perspective25
Reposition of the Fungicide Ciclopirox for Cancer Treatment21
Cancer Immunotherapy - Immune Checkpoint Inhibitors in Hepatocellular Carcinoma18
Current Advances and Outlook in Gastric Cancer Chemoresistance: A Review18
Phytochemicals as PI3K/ Akt/ mTOR Inhibitors and Their Role in Breast Cancer Treatment18
Potential Therapeutic Targets of Curcumin, Most Abundant Active Compound of Turmeric Spice: Role in the Management of Various Types of Cancer17
Effect of PI3K/AKT/mTOR Signaling Pathway on Regulating and Controlling the Anti-Invasion and Metastasis of Hepatoma Cells by Bufalin15
A Link Between Chemical Structure and Biological Activity in Triterpenoids15
Gefitinib: An Updated Review of its Role in the Cancer Management, its Nanotechnological Interventions, Recent Patents and Clinical Trials14
Distinct Epigenetic Reprogramming, Mitochondrial Patterns, Cellular Morphology, and Cytotoxicity after Bee Venom Treatment13
Current Status and Prospects of Camrelizumab, A Humanized Antibody Against Programmed Cell Death Receptor 113
Imitating Hypoxia and Tumor Microenvironment with Immune Evasion by Employing Three Dimensional In vitro Cellular Models: Impressive Tool in Drug Discovery12
Interplay between RNA Methylation Eraser FTO and Writer METTL3 in Renal Clear Cell Carcinoma Patient Survival11
Targeting Cancer Stem Cells with Repurposed Drugs to Improve Current Therapies11
The Patent Landscape of BRAF Target and KRAS Target11
Induced Fit Docking and Automated QSAR Studies Reveal the ER-α Inhibitory Activity of Cannabis sativa in Breast Cancer10
LINC00936/microRNA-221-3p Regulates Tumor Progression in Ovarian Cancer by Interacting with LAMA310
N6-Methyladenosine-Related RNA Signature Predicting the Prognosis of Ovarian Cancer10
The Efficacy and Mechanism of Proteasome Inhibitors in Solid Tumor Treatment10
Research and Patents Status of Selected Phytochemicals Against Cancer: How Close and How Far?10
In Vitro and In Vivo Evaluation of Novel DTX-Loaded Multifunctional Heparin-Based Polymeric Micelles Targeting Folate Receptors and Endosomes10
Self-immolative Linkers in Prodrugs and Antibody Drug Conjugates in Cancer Treatment10
Repurposing Chloroquine Analogs as an Adjuvant Cancer Therapy10
Anti-EGFR-mAb and 5-Fluorouracil Conjugated Polymeric Nanoparticles for Colorectal Cancer10
Immunological Mechanism and Clinical Application of PAMP Adjuvants9
Transdermal Drug Delivery: A Step towards Treatment of Cancer9
Eudragit, a Nifty Polymer for Anticancer Preparations: A Patent Review9
Terpenes with Antitumor Activity: A Patent Review9
Artificial Intelligence and Cancer Drug Development9
Advancement of Traditional Chinese Medicine in Regulation of Intestinal Flora: Mechanism-based Role in Disease Management8
Novel Pathways and Mechanisms of Nicotine-Induced Oral Carcinogenesis8
Recent Trend for EGFR-Based and ALK-Based Targets: A Patent Analysis8
The Impact of Polyphenolics in the Management of Breast Cancer: Mechanistic Aspects and Recent Patents8
Metallodrugs as Anticancer Chemotherapeutics and Diagnostic Agents: A Critical Patent Review (2010-2020)8
Repurposing of Metformin for Cancer Therapy: Updated Patent and Literature Review8
Anti-Cancer Effect of Melatonin via Downregulation of Delta-like Ligand 4 in Estrogen-Responsive Breast Cancer Cells8
Anti-cancer Research on Arnebiae radix-derived Naphthoquinone in Recent Five Years8
Understanding and Targeting the Epigenetic Regulation to Overcome EGFR-TKIs Resistance in Human Cancer8
The Synthesis, Structural Modification and Mode of Anticancer Action of Evodiamine: A Review7
Natural Product as Substrates of ABC Transporters: A Review7
High Expression of MYL9 Indicates Poor Clinical Prognosis of Epithelial Ovarian Cancer7
Ultrasound-Mediated Cancer Therapeutics Delivery using Micelles and Liposomes: A Review7
Nano-Based Drug Delivery of Anticancer Chemotherapeutic Drugs Targeting Breast Cancer7
STAT3 Inhibitor Napabucasin Inhibits Tumor Growth and Cooperates with Proteasome Inhibition in Human Ovarian Cancer Cells7
Combining PD-1 Inhibitor with VEGF/VEGFR2 Inhibitor in Chemotherapy: Report of a Patient with End-Stage Cholangiocarcinoma and Review of Literature7
Anti-EGFR Binding Nanobody Delivery System to Improve the Diagnosis and Treatment of Solid Tumours7
Multifunctional Patented Nanotherapeutics for Cancer Intervention: 2010- Onwards6
The Application of Nanotechnology in Immunotherapy based Combinations for Cancer Treatment6
Overview of Inorganic Nanoparticles: An Expanding Horizon in Tumor Therapeutics6
Prognostic and Therapeutic Values of Autophagy-related Genes in Triple-negative Breast Cancer6
Pseudo-ginsenoside Rh2 Induces Protective Autophagy in Hepatocellular Carcinoma HepG2 Cells6
An Update of Lysine Specific Demethylase 1 Inhibitor: A Patent Review (2016-2020)6
Gliotoxin Induced Ferroptosis by Downregulating SUV39H1 Expression in Esophageal Cancer Cells6
Exploring the Anticancer Potentials of Polyphenols: A Comprehensive Review of Patents in the Last Five Years6
ZFP36L1 Promotes Gastric Cancer Progression via Regulating JNK and p38 MAPK Signaling Pathways6
pH-responsive Sulfated Hyaluronic Acid Nanoparticles Targeting Tumor Cells and CAFs for the Treatment of Breast Cancer5
Prediction of Cancer Treatment Using Advancements in Machine Learning5
Alpha-solanine Anti-tumor Effects in Non-small Cell Lung Cancer Through Regulating the Energy Metabolism Pathway5
Prospective Challenges for Patenting and Clinical Trials of Anticancer Compounds from Natural Products: Coherent Review5
Recent Patents of Pharmaceutical Co-Crystals: Product Development on Anti-Cancer Drugs and Beyond5
Human Saliva Metabolome for Oral Lichen Planus Biomarker Identification5
Daidzein and Chicory Extract Arrest the Cell Cycle via Inhibition of Cyclin D/CDK4 and Cyclin A/CDK2 Gene Expression in Hepatocellular Carcinoma5
Antioxidant, Anti-Inflammatory and Anticancer Activities of the Methanolic Extract of Thottea siliquosa: An In Vitro and In Silico Study5
MiR-125b Inhibits Cell Proliferation and Induces Apoptosis in Human Colon Cancer SW480 Cells via Targeting STAT35
Network Pharmacology-based Prediction and Verification of Shikonin for Treating Colorectal Cancer5
Regression of Breast Cancer Metastases Following Treatment with Irradiated SV-BR-1-GM, a GM-CSF Overexpressing Breast Cancer Cell Line: Intellectual Property and Immune Markers of Response5
The Dichloromethane Fraction of Vernonia cinerea Impart Pro-Apoptotic, Genotoxic, Cell Cycle Arrest, and Drug Efflux Inhibitory Effects on Human Adenocarcinoma Cells4
KRAS Pathways: A Potential Gateway for Cancer Therapeutics and Diagnostics4
The JPJDF has Synergistic Effect with Fluoropyrimidine in the Maintenance Therapy for Metastatic Colorectal Cancer4
Qigefang Inhibits Migration, Invasion, and Metastasis of ESCC by Inhibiting Gas6/Axl Signaling Pathway4
Recent Patents on the Development of c-Met Kinase Inhibitors4
Examining the Mechanisms of Huachansu Injection on Liver Cancer through Integrated Bioinformatics Analysis4
lncRNA H22954 Inhibits Angiogenesis in Acute Myeloid Leukemia through a PDGFA-dependent Mechanism4
Downregulation of miRNA-14669 Reverses Vincristine Resistance in Colorectal Cancer Cells through PI3K/AKT Signaling Pathway4
Targeting Notch Pathway in Cancer Diagnostics and Therapeutics: An Emerging Approach4
Matrix Metalloproteinase-2 (MMP-2): As an Essential Factor in Cancer Progression4
Non-histone Methylation of SET7/9 and its Biological Functions4
Recent Progress in Natural Anticancer Agents Discovery from Tea (Camellia sinensis): A Review4
Ribosome-inactivating Protein MAP30 Isolated from Momordica Charantia L. Induces Apoptosis in Hepatocellular Carcinoma Cells4
Inhibiting the Activity of ABCG2 by KU55933 in Colorectal Cancer4
Current Prospects for Adrenocortical Carcinoma Pharmacotherapy4
A Patent Review of Human Dihydroorotate Dehydrogenase (hDHODH) Inhibitors as Anticancer Agents and their Other Therapeutic Applications (1999-2022)4
Cancer Stem Cells and their Management in Cancer Therapy4
Pemetrexed – First-Line Therapy for Non-Squamous Non-Small Cell Lung Cancer: A Review of Patent Literature4
The Synergistic Effect of Ruthenium Complex Δ-Ru1 and Doxorubicin in a Mouse Breast Cancer Model4
Phytochemicals and Nanoparticles in the Modulation of PI3K/Akt/mTOR Kinases and its Implications in the Development and Progression of Gastrointestinal Cancers: A Review of Preclinical and Clinical Ev4
Targeted Therapies in Lung Cancers: Current Landscape and Future Prospects3
Development and Validation of a Hypoxia-related Prognostic Model for Ovarian Cancer3
Recent Patent-Based Perspective on Diagnostic and Therapeutic Interventions in Malignant Mesothelioma: Is Drug Repositioning Knocking on the Door?3
Fatty Acid Synthase (FASN): A Patent Review Since 2016-Present3
Expression and Clinical Significance of Microtubule-Actin Cross-Linking Factor 1 in Serous Ovarian Cancer3
Comprehensive Genomic Analysis of Puerarin in Inhibiting Bladder Urothelial Carcinoma Cell Proliferation and Migration3
The Efficacy and Safety of Anlotinib Alone and in Combination with Other Drugs in Previously Treated Advanced Thymic Epithelia Tumors: A Retrospective Analysis3
CRISPER/Cas in Plant Natural Product Research: Therapeutics as Anticancer and other Drug Candidates and Recent Patents3
Gene Expression Network and Circ_0008012 Promote Progression in MLL/AF4 Positive Acute Lymphoblastic Leukemia3
Antibody-drug Conjugates for Breast Cancer Treatment3
Recent Patents on Plant-Derived Nanoparticles and their Potential Application Towards Various Cancer Therapeutics3
Neochamaejasmine A Promotes Apoptosis and Cell Cycle Arrest in B16F10 Melanoma Cells via JNK and p38 MAPK Signaling Pathway3
Natural STAT3 Inhibitors for Cancer Treatment: A Comprehensive Literature Review3
The Influence of Wuzhi Capsule on the Pharmacokinetics of Cyclophosphamide3
Potential Therapeutic Application of Local Anesthetics in Cancer Treatment3
YBX1, Targeted By Microrna-382-5p, Promotes Laryngeal Squamous Cell Carcinoma Progression via Modulating RAS/MAPK Signaling3
Curcumin Inhibits the Growth of Hepatocellular Carcinoma via the MARCH1-mediated Modulation of JAK2/STAT3 Signaling3
Next Generation Sequencing in the Management of Leptomeningeal Metastases of Non-Small Cell Lung Cancer: A Case Report and Literature Review3
Recent Advances in the Development of Selective Mcl-1 Inhibitors for the Treatment of Cancer (2017-Present)3
Altering Landscape of Cancer Vaccines: Unique Platforms, Research on Therapeutic Applications and Recent Patents3
Circular RNA NF1-419 Inhibits Proliferation and Induces Apoptosis by Regulating Lipid Metabolism in Astroglioma Cells3
Nanomaterials for Diagnosis and Treatment of Lung Cancer: A Review of Recent Patents2
Anti-HER2 VHH Targeted Fluorescent Liposome as Bimodal Nanoparticle for Drug Delivery and Optical Imaging2
Bourgeoning Cancer Targets2
Chitosan - A Potential Polymer to Prepare Anticancer Drug Delivery Systems: Patent Review2
β-estradiol Induces Mitochondrial Apoptosis in Cervical Cancer through the Suppression of AKT/NF-κB Signaling Pathway2
The Effect of Acetylsalicylic Acid (Asa) on the Mechanical Properties of Breast Cancer Epithelial Cells2
SSPH I, A Novel Anti-cancer Saponin, Inhibits EMT and Invasion and Migration of NSCLC by Suppressing MAPK/ERK1/2 and PI3K/AKT/ mTOR Signaling Pathways2
Santacruzamate A Compositions, Analogs and Methods of Use: A Patent Evaluation of WO 2014/018913 (A2)2
Pharmacological Potentials and Nutritional Values of Tropical and Subtropical Fruits of India: Emphasis on their Anticancer Bioactive Components2
Green Synthesized Nanoparticles as a Plausible Therapeutic Strategy Against Hepatocellular Carcinoma: An Update on its Preclinical and Clinical Relevance2
Knockdown of RhoA Expression Reverts Enzalutamide Resistance via the p38 MAPK Pathway in Castration-resistant Prostate Cancer2
Clinical CDK2 Inhibitors: Trends to Selectivity and Efficacy2
The Anti-Tumor Mechanism and Target of Triptolide Based on Network Pharmacology and Molecular Docking2
Monoclonal Antibodies, Bispecific Antibodies and Antibody-Drug Conjugates in Oncohematology2
Preface2
Characterization of the Prognosis and Tumor Microenvironment of Cellular Senescence-related Genes through scRNA-seq and Bulk RNA-seq Analysis in GC2
Current Status and Future Perspectives on Old Drug Repurposing for Cancer Treatment2
Metformin Inhibits NLRP3 Inflammasome Expression and Regulates Inflammatory Microenvironment to Delay the Progression of Colorectal Cancer2
Chebulinic Acid: An Incipient Anticancer Agent1
Development of a Prognostic Risk Model Based on Oxidative StressRelated Genes for Platinum-Resistant Ovarian Cancer Patients1
Siah2 Inhibitor and the Metabolic Antagonist Oxamate Retard Colon Cancer Progression and Downregulate PD1 Expression1
PSMA PET/MR is a New Imaging Option for Identifying Glioma Recurrence and Predicting Prognosis1
A Synergistic Combination of Oleanolic Acid and Apatinib to Enhance Antitumor Effect on Liver Cancer Cells and Protect against Hepatic Injury1
Strategies for Developing Cancer Theranostics Approaches1
Rho GTPase Activating Protein 9 (ARHGAP9) in Human Cancers1
A Combined Bioinformatic and Nanoparticle-Based Study Reveal the Role of ABCG2 in the Drug Resistant Breast Cancer1
Optimal Rituximab Monotherapy in Splenic Marginal Zone Lymphoma (SMZL): A Case Report and Brief Review1
The Validity of Mobile Applications to Facilitate Patient Care Provided to Cancer Patients: Opportunities and Limitations1
The Anti-Proliferative Effect of a Newly-Produced Anti-PSCA-Peptide Antibody by Multiple Bioinformatics Tools, on Prostate Cancer Cells1
Exosome-Derived Cargos in Immune Microenvironment in Esophageal Carcinoma: A Mini-Review1
Synthesis and Anticancer Evaluation of Sulfur Containing 9-anilinoacridines1
The Role of KCNMA1 Expression in Digestive Cancers: A Potential Prognostic Biomarker1
Meet Our Associate Editorial Board Member1
RNA Splicing: Basic Aspects Underlie Antitumor Targeting1
Chlorogenic Acid Inhibits Proliferation, Migration and Invasion of Pancreatic Cancer Cells via AKT/GSK-3β/β-catenin Signaling Pathway1
The Non-hodgkin Lymphoma Treatment and Side Effects: A Systematic Review and Meta-analysis1
Novel 4-chloro-N-phenyl Benzamide Derivatives as p38α Mitogenactivated Protein Kinase Inhibitors for Treating Cancer, COVID-19, and Other Diseases1
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