Recent Patents on Anti-Cancer Drug Discovery

Papers
(The median citation count of Recent Patents on Anti-Cancer Drug Discovery is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Acknowledgement to Contributors41
Acknowledgement to Reviewers25
L-Selenomethylselenocysteine Exerts Inhibitory Effects on the Progression of Esophageal Cancer by Targeting the PI3K/AKT Signaling Pathway22
High Expression of MYL9 Indicates Poor Clinical Prognosis of Epithelial Ovarian Cancer18
Advanced Strategies of CAR-T Cell Therapy in Solid Tumors and Hematological Malignancies17
Current Prospects for Adrenocortical Carcinoma Pharmacotherapy17
Research Progress on the Anticancer Activity of Plant Polysaccharides16
Comprehensive Genomic Analysis of Puerarin in Inhibiting Bladder Urothelial Carcinoma Cell Proliferation and Migration16
Patent Selections15
The Prognostic Role of Interferon Gamma-inducible Protein 30 in Clear Cell Renal Cell Carcinoma with Immune Infiltrates15
Statin Use and Hepatocellular Carcinoma Risk: A Comprehensive Meta-Analysis and Systematic Review14
Santacruzamate A Compositions, Analogs and Methods of Use: A Patent Evaluation of WO 2014/018913 (A2)14
Bioinformatic Analysis and Experimental Validation of HMGA2-AS1 as a Prognostic Biomarker Associated with Immune Infiltration in Gastric Cancer14
Nanomaterials for Diagnosis and Treatment of Lung Cancer: A Review of Recent Patents14
Protective Assessment of Novel (BNC Formulation) against Brain Tumor14
Radiotherapy Enhancing and Radioprotective Properties of Berberine: A Systematic Review13
Oral Metronomic Chemotherapy in Nasopharyngeal Carcinoma with Radiotherapy Interruptions: A Lesson Learned from the Lockdown Due to COVID-1913
The Application of Nanotechnology in Immunotherapy based Combinations for Cancer Treatment13
The Present State and Potential Applications of Artificial Intelligence in Cancer Diagnosis and Treatment13
Network Pharmacology-based Prediction and Verification of Shikonin for Treating Colorectal Cancer12
Prognostic Value of Fatty Acid Metabolism-related Genes in Patients with Bladder Cancer12
Alpha-solanine Anti-tumor Effects in Non-small Cell Lung Cancer Through Regulating the Energy Metabolism Pathway12
USP31 Activates the Wnt/β-catenin Signaling Pathway and Promotes Gastric Cancer Cell Proliferation, Invasion and Migration11
Acknowledgement To Reviewers11
Bioinformatics Analysis of Key Genes Associated with Resistance to the Combination of Bevacizumab and Pemetrexed Chemotherapy in Non-small Cell Lung Cancer10
Integrated Single-cell and Bulk RNA Sequencing Analysis Cross Talk between Ferroptosis-related Genes and Prognosis in Oral Cavity Squamous Cell Carcinoma10
Self-immolative Linkers in Prodrugs and Antibody Drug Conjugates in Cancer Treatment10
Regulating Lipid Metabolism via Mitochondrial Dynamics in Tongue Squamous Cell Carcinoma Cancer Stem Cells10
Vitexin’s Role in Colon Cancer Apoptosis: AMPK/mTOR Pathway Modulation Explored Through Experimental and Computational Approaches10
Predictive Modelling of Overall Survival in Adult Patients with Primary Diffuse Large B-cell Lymphoma of the Breast Using the Surveillance, Epidemiology, and End Results (SEER) Database9
Patent Selections9
The Causal Effects of Cholelithiasis on Acute Pancreatitis and Pancreatic Cancer: A Large Sample Size Mendelian Randomization Analysis9
Prospective Challenges for Patenting and Clinical Trials of Anticancer Compounds from Natural Products: Coherent Review9
Bourgeoning Cancer Targets9
Survival Benefits of Ganoderma Lucidum in Early-stage Triple-negative Breast Cancer: A Real World Study9
Screening of Candidate Inflammatory Markers of Epithelial Cells in Hepatocellular Carcinoma based on Integration Analysis of TCGA/ICGC Databases and Single-cell Sequencing9
Mechanisms of Anti-PD Therapy Resistance in Digestive System Neoplasms9
Intracholecystic Papillary-tubular Neoplasm (ICPN) of the Gallbladder: A Case Report Focusing on an Unexpected Pathological Finding8
Ubiquitination-related Gene UBTD1 Mediates Poor Prognosis of Colorectal Cancer and Affects Colorectal Cancer Cell Proliferation and Ferroptosis8
Targeting the Key Signaling Pathways in Breast Cancer: From Molecular Mechanism to Therapeutic Interventions8
Metallodrugs as Anticancer Chemotherapeutics and Diagnostic Agents: A Critical Patent Review (2010-2020)8
Patent Selections8
Meet the Editorial Board Member8
lncRNA H22954 Inhibits Angiogenesis in Acute Myeloid Leukemia through a PDGFA-dependent Mechanism8
Application of Nano Drug Delivery System (NDDS) in Cancer Therapy: A Perspective8
The m6A Reader IGF2BP2 Promotes Oral Squamous Cell Carcinoma Progression by Maintaining UCA1 Stability8
Circular RNA NF1-419 Inhibits Proliferation and Induces Apoptosis by Regulating Lipid Metabolism in Astroglioma Cells8
Natural STAT3 Inhibitors for Cancer Treatment: A Comprehensive Literature Review8
SSPH I, A Novel Anti-cancer Saponin, Inhibits EMT and Invasion and Migration of NSCLC by Suppressing MAPK/ERK1/2 and PI3K/AKT/ mTOR Signaling Pathways8
Construction and Identification of a Human Colorectal Adenoma Epithelial Cell Line by SV40 Large T-antigen Transfection7
The Synergistic Effect of Ruthenium Complex Δ-Ru1 and Doxorubicin in a Mouse Breast Cancer Model7
Targeted Regulation of Osteoblasts and Osteoclasts in Osteosarcoma Patients by CSF3R Receptor Inhibition of Osteolysis Caused by Tumor Inflammation Based on Transcriptional Spectrum Analysis and Drug 7
Puerarin: An Anticancer and Anti-Inflammatory Agent7
The FJQR Has Synergistic Effect with Fluoropyrimidine in the Maintenance Treatment for HER-2 Negative Gastric Cancer7
Preface7
Fatty Acid Synthase (FASN): A Patent Review Since 2016-Present7
Patent Selections6
Exploring the Anticancer Potentials of Polyphenols: A Comprehensive Review of Patents in the Last Five Years6
Investigating the Therapeutic Potential and Molecular Mechanisms of Daphnetin: A Comprehensive Review6
UBE2L3 Suppresses Oxidative Stress-regulated Necroptosis to Accelerate Osteosarcoma Progression6
Advances in the Treatment of Chronic Myeloid Leukemia6
pH-responsive Sulfated Hyaluronic Acid Nanoparticles Targeting Tumor Cells and CAFs for the Treatment of Breast Cancer6
Prognostic and Therapeutic Values of Autophagy-related Genes in Triple-negative Breast Cancer6
Adverse Effects of Gefitinib on Skin and Colon in a Lung Cancer Mouse Model6
Exploring the Molecular Mechanisms and Biological Effects of CELF2 in the Development of Gastric Cancer5
Targeting Notch Pathway in Cancer Diagnostics and Therapeutics: An Emerging Approach5
Morusin Suppresses Pancreatic Cancer Cell Proliferation and Migration by Targeting SLC6A12 to Inhibit NF-κB and β-catenin Signaling Pathways5
Development of a Novel Lipid Metabolism-related Gene Prognostic Signature for Patients with Colorectal Cancer5
Nano-carriers based Approaches Loaded with Herbal Bioactive Compounds for the Treatment of Cancer: Recent Updates and Future Prospects5
A Synergistic Combination of Oleanolic Acid and Apatinib to Enhance Antitumor Effect on Liver Cancer Cells and Protect against Hepatic Injury5
KRAS Pathways: A Potential Gateway for Cancer Therapeutics and Diagnostics5
LINC00936/microRNA-221-3p Regulates Tumor Progression in Ovarian Cancer by Interacting with LAMA35
Daidzein and Chicory Extract Arrest the Cell Cycle via Inhibition of Cyclin D/CDK4 and Cyclin A/CDK2 Gene Expression in Hepatocellular Carcinoma5
Patent Selections5
LMNB1 and LMNB2 as Prognostic Risk Factors in Hepatocellular Carcinoma: Therapeutic Potential of GSK461364 via Downregulation of LMNB1 and LMNB2 Expression5
Patents on PARP-1 Inhibitors for the Management of Cancer from 2017-20235
Ribosome-inactivating Protein MAP30 Isolated from Momordica Charantia L. Induces Apoptosis in Hepatocellular Carcinoma Cells4
ZFP36L1 Promotes Gastric Cancer Progression via Regulating JNK and p38 MAPK Signaling Pathways4
Epigallocatechin Gallate Derivative Y6 Reverses Oxaliplatin Resistance in Hepatocellular Carcinoma via Targeting the MiR-338-3p/HIF-1α/TWIST Axis to Inhibit EMT4
Exosome-Derived Cargos in Immune Microenvironment in Esophageal Carcinoma: A Mini-Review4
Targeting Ferroptosis as a New Approach for Radiation Protection and Mitigation4
Structure-Based Virtual Screening of Novel FOXM1 Inhibitors as Potential Compounds for Glioblastoma Treatment4
Strategies for Developing Cancer Theranostics Approaches4
Patent Selections4
Differentiation of Acute Leukemia Cells Including Cells with MLL-AF4 Rearrangements Induced by Jiyuan Oridonin A3
Patent Selections3
Green Synthesized Nanoparticles as a Plausible Therapeutic Strategy Against Hepatocellular Carcinoma: An Update on its Preclinical and Clinical Relevance3
New 1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-2-phenylisoquinoline-1(2H)-ones as Phosphoinositide 3-kinase Inhibitors for Treating Cancer and Other Diseases3
Altering Landscape of Cancer Vaccines: Unique Platforms, Research on Therapeutic Applications and Recent Patents3
Identification of Breast Cancer Immune-related Prognostic Characteristics in Tumor Microenvironment3
β-estradiol Induces Mitochondrial Apoptosis in Cervical Cancer through the Suppression of AKT/NF-κB Signaling Pathway3
Adhesin Component Member STAG2 Enhances Cisplatin Tolerance in Colorectal Cancer Cells through the Epithelial-Mesenchymal Transition Pathway3
Recent Patents of Pharmaceutical Co-Crystals: Product Development on Anti-Cancer Drugs and Beyond3
Eukaryotic Initiation Factor 3C Can Affect the Proliferation and Invasion of Ovarian Cancer by Regulating the p53 Signalling Pathway3
Meet the Editorial Board Member3
Antibody-drug Conjugates for Breast Cancer Treatment3
A Single-arm, Open-label, Phase Ib Clinical Study Evaluating the Efficacy and Safety of Durvalumab in Combination with Albumin-bound Paclitaxel and Carboplatin as Neoadjuvant Therapy for Resectable St3
TGF-β Score based on Silico Analysis can Robustly Predict Prognosis and Immunological Characteristics in Lower-grade Glioma: The Evidence from Multicenter Studies3
The Impact of Polyphenolics in the Management of Breast Cancer: Mechanistic Aspects and Recent Patents2
Patent Selections2
Unveiling miR-1468-5p: A New Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma2
Development and Evaluation of a Novel Hyaluronic Acid and Chitosan-modified Phytosome for Co-delivery of Oxymatrine and Glycyrrhizin for Combination Therapy2
Patent Selections2
Metal Nanoparticles as Emerging Drug Candidates in the Management of Cancers and Microbial Infectious Diseases2
1,3,4-Oxadiazoles as Anticancer Agents: A Review2
Nanotechnology a Boon for Colorectal Cancer Treatment2
The Role of KCNMA1 Expression in Digestive Cancers: A Potential Prognostic Biomarker2
Dahuang Zhechong Pill Combined with TNS4 Silencing Inhibits the NF-Κb/VEGF Pathway To Slow Down The Progression Of Pancreatic Cancer2
Downregulation of miRNA-14669 Reverses Vincristine Resistance in Colorectal Cancer Cells through PI3K/AKT Signaling Pathway2
Preclinical Effects of Melatonin on the Development of Ehrlich's Tumor: A Biochemical, Cognitive, and Molecular Approach2
Nano-Based Drug Delivery of Anticancer Chemotherapeutic Drugs Targeting Breast Cancer2
Ultrasound-Mediated Cancer Therapeutics Delivery using Micelles and Liposomes: A Review2
Competitive Effect of Overexpressed C-terminal of Snail-1 (CSnail) in Control of the Growth and Metastasis of Melanoma Cells2
Updated Progress on Mass Spectrometry Imaging and its Application in Cancer Treatment and Drug Discovery2
Meet the Associate Editorial Board Member2
Increased SLC7A3 Expression Inhibits Tumor Cell Proliferation and Predicts a Favorable Prognosis in Breast Cancer2
Phytochemicals and Nanoparticles in the Modulation of PI3K/Akt/mTOR Kinases and its Implications in the Development and Progression of Gastrointestinal Cancers: A Review of Preclinical and Clinical Ev2
Transdermal Drug Delivery: A Step towards Treatment of Cancer2
B-9-8, a Novel Harman Dimer, Reverses ABCG2-mediated Chemotherapeutic Drug Resistance1
PDLIM1 Inhibits Chemoresistance by Blocking DNA Damage Repair in Gastric Cancer1
LncRNA FAM83H-AS1 Contributes to the Radio-resistance and Proliferation in Liver Cancer through Stability FAM83H Protein1
The Non-hodgkin Lymphoma Treatment and Side Effects: A Systematic Review and Meta-analysis1
TENT5A Increases Glioma Malignancy and Promotes its Progression1
Identification of Immune Infiltration-related Molecular Features in Ovarian Cancer Patients and Experimental Validation of Immune Response Molecular Mechanisms through Integrated WGCNA, Machine Learni1
Sema3A Affect Osteolytic Bone Metastasis of Non-small Cell Lung Cancer1
Knockdown of RhoA Expression Reverts Enzalutamide Resistance via the p38 MAPK Pathway in Castration-resistant Prostate Cancer1
Prediction of Cancer Treatment Using Advancements in Machine Learning1
Acknowledgements to Reviewer1
Withdrawn: Fumarate-1 Mediates the Regulation of Mitochondrial Homeostasis by PGC-1α to Promote Cell Pyroptosis and Inhibit the Thyroid Cancer1
Neochamaejasmine A Promotes Apoptosis and Cell Cycle Arrest in B16F10 Melanoma Cells via JNK and p38 MAPK Signaling Pathway1
Pseudo-ginsenoside Rh2 Induces Protective Autophagy in Hepatocellular Carcinoma HepG2 Cells1
Inhibiting the Activity of ABCG2 by KU55933 in Colorectal Cancer1
West African Medicinal Plant Substances and Molecules Activities Against Viral Hepatitis B and Hepatocellular Carcinoma1
Roles of TEAD Transcription Factors and their Coactivators in the Progression and Metastasis of Cancers1
The ER Stress-related Gene Prognostic Signature for Predicting Chemosensitivity and Prognosis in AML1
Gefitinib: An Updated Review of its Role in the Cancer Management, its Nanotechnological Interventions, Recent Patents and Clinical Trials1
The Patent Landscape of BRAF Target and KRAS Target1
A Descriptive Review of Cannabis sativa Patents for Cancer Treatment1
A Link Between Chemical Structure and Biological Activity in Triterpenoids1
From Multiple Myeloma to Acute Myeloid Leukemia: A Case Report of a 61-year-old Woman after 8 Years of Chemotherapy and Immunotherapy1
Selinexor as a Therapeutic Target: Advances in Non-small Cell and Small Cell Lung Cancer Treatment Strategies1
The Clinical Significance and Prognostic Value of ALDH1 Expression in Non-small Cell Lung Cancer: A Systematic Review and Meta-analysis1
Recent Progress in Natural Anticancer Agents Discovery from Tea (Camellia sinensis): A Review1
Acknowledgements to Contributor1
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