Recent Patents on Anti-Cancer Drug Discovery

Papers
(The median citation count of Recent Patents on Anti-Cancer Drug Discovery is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
ArticleCitations
Developments in the Application of 1,2,3-Triazoles in Cancer Treatment39
Novel Selective Histone Deacetylase 6 (HDAC6) Inhibitors: A Patent Review (2016-2019)21
Reposition of the Fungicide Ciclopirox for Cancer Treatment16
Cancer Immunotherapy - Immune Checkpoint Inhibitors in Hepatocellular Carcinoma16
Phytochemicals as PI3K/ Akt/ mTOR Inhibitors and Their Role in Breast Cancer Treatment16
Current Advances and Outlook in Gastric Cancer Chemoresistance: A Review15
Application of Nano Drug Delivery System (NDDS) in Cancer Therapy: A Perspective14
Effect of PI3K/AKT/mTOR Signaling Pathway on Regulating and Controlling the Anti-Invasion and Metastasis of Hepatoma Cells by Bufalin14
Potential Therapeutic Targets of Curcumin, Most Abundant Active Compound of Turmeric Spice: Role in the Management of Various Types of Cancer13
Current Status and Prospects of Camrelizumab, A Humanized Antibody Against Programmed Cell Death Receptor 112
Alkaloids as Anticancer Agents: A Review of Chinese Patents in Recent 5 Years11
Anti-EGFR-mAb and 5-Fluorouracil Conjugated Polymeric Nanoparticles for Colorectal Cancer11
Targeting Cancer Stem Cells with Repurposed Drugs to Improve Current Therapies11
Feasibility of Repurposing Clioquinol for Cancer Therapy11
Bortezomib – First Therapeutic Proteasome Inhibitor for Cancer Therapy: A Review of Patent Literature11
Interplay between RNA Methylation Eraser FTO and Writer METTL3 in Renal Clear Cell Carcinoma Patient Survival10
Distinct Epigenetic Reprogramming, Mitochondrial Patterns, Cellular Morphology, and Cytotoxicity after Bee Venom Treatment10
In Vitro and In Vivo Evaluation of Novel DTX-Loaded Multifunctional Heparin-Based Polymeric Micelles Targeting Folate Receptors and Endosomes10
LINC00936/microRNA-221-3p Regulates Tumor Progression in Ovarian Cancer by Interacting with LAMA39
Gefitinib: An Updated Review of its Role in the Cancer Management, its Nanotechnological Interventions, Recent Patents and Clinical Trials9
The Patent Landscape of BRAF Target and KRAS Target9
Immunological Mechanism and Clinical Application of PAMP Adjuvants8
The Molecular Docking of Flavonoids Isolated from Daucus carota as a Dual Inhibitor of MDM2 and MDMX8
Repurposing of Metformin for Cancer Therapy: Updated Patent and Literature Review8
Artificial Intelligence and Cancer Drug Development8
N6-Methyladenosine-Related RNA Signature Predicting the Prognosis of Ovarian Cancer8
The Efficacy and Mechanism of Proteasome Inhibitors in Solid Tumor Treatment8
Induced Fit Docking and Automated QSAR Studies Reveal the ER-α Inhibitory Activity of Cannabis sativa in Breast Cancer8
Recent Trend for EGFR-Based and ALK-Based Targets: A Patent Analysis8
Recent Patents on Anti-Cancer Potential of Helenalin7
Research and Patents Status of Selected Phytochemicals Against Cancer: How Close and How Far?7
Expression of B Cell Translocation Gene 1 Protein in Colon Carcinoma and its Clinical Significance7
Imitating Hypoxia and Tumor Microenvironment with Immune Evasion by Employing Three Dimensional In vitro Cellular Models: Impressive Tool in Drug Discovery7
Natural Product as Substrates of ABC Transporters: A Review7
High Expression of MYL9 Indicates Poor Clinical Prognosis of Epithelial Ovarian Cancer7
Anti-Cancer Effect of Melatonin via Downregulation of Delta-like Ligand 4 in Estrogen-Responsive Breast Cancer Cells7
Self-immolative Linkers in Prodrugs and Antibody Drug Conjugates in Cancer Treatment7
Repurposing Chloroquine Analogs as an Adjuvant Cancer Therapy7
Advancement of Traditional Chinese Medicine in Regulation of Intestinal Flora: Mechanism-based Role in Disease Management6
Novel Pathways and Mechanisms of Nicotine-Induced Oral Carcinogenesis6
Anti-cancer Research on Arnebiae radix-derived Naphthoquinone in Recent Five Years6
Transdermal Drug Delivery: A Step towards Treatment of Cancer6
The Synthesis, Structural Modification and Mode of Anticancer Action of Evodiamine: A Review6
Pseudo-ginsenoside Rh2 Induces Protective Autophagy in Hepatocellular Carcinoma HepG2 Cells6
Overview of Inorganic Nanoparticles: An Expanding Horizon in Tumor Therapeutics5
Anti-EGFR Binding Nanobody Delivery System to Improve the Diagnosis and Treatment of Solid Tumours5
The Impact of Polyphenolics in the Management of Breast Cancer: Mechanistic Aspects and Recent Patents5
Nano-Based Drug Delivery of Anticancer Chemotherapeutic Drugs Targeting Breast Cancer5
Antioxidant, Anti-Inflammatory and Anticancer Activities of the Methanolic Extract of Thottea siliquosa: An In Vitro and In Silico Study5
Daidzein and Chicory Extract Arrest the Cell Cycle via Inhibition of Cyclin D/CDK4 and Cyclin A/CDK2 Gene Expression in Hepatocellular Carcinoma5
STAT3 Inhibitor Napabucasin Inhibits Tumor Growth and Cooperates with Proteasome Inhibition in Human Ovarian Cancer Cells5
Modulation of MicroRNAs by Euphorbia Microsciadia Boiss in MDA-MB-231 Cell Line: New Possibilities in Breast Cancer Therapy5
An Update of Lysine Specific Demethylase 1 Inhibitor: A Patent Review (2016-2020)5
Prospective Challenges for Patenting and Clinical Trials of Anticancer Compounds from Natural Products: Coherent Review5
Terpenes with Antitumor Activity: A Patent Review5
Understanding and Targeting the Epigenetic Regulation to Overcome EGFR-TKIs Resistance in Human Cancer5
pH-responsive Sulfated Hyaluronic Acid Nanoparticles Targeting Tumor Cells and CAFs for the Treatment of Breast Cancer4
Qigefang Inhibits Migration, Invasion, and Metastasis of ESCC by Inhibiting Gas6/Axl Signaling Pathway4
Recent Patents on the Development of c-Met Kinase Inhibitors4
Recent Progress in Natural Anticancer Agents Discovery from Tea (Camellia sinensis): A Review4
Metallodrugs as Anticancer Chemotherapeutics and Diagnostic Agents: A Critical Patent Review (2010-2020)4
Downregulation of miRNA-14669 Reverses Vincristine Resistance in Colorectal Cancer Cells through PI3K/AKT Signaling Pathway4
SOX4 Serves an Oncogenic Role in the Tumourigenesis of Human Breast Adenocarcinoma by Promoting Cell Proliferation, Migration and Inhibiting Apoptosis4
MiR-125b Inhibits Cell Proliferation and Induces Apoptosis in Human Colon Cancer SW480 Cells via Targeting STAT34
Combining PD-1 Inhibitor with VEGF/VEGFR2 Inhibitor in Chemotherapy: Report of a Patient with End-Stage Cholangiocarcinoma and Review of Literature4
Exploring the Anticancer Potentials of Polyphenols: A Comprehensive Review of Patents in the Last Five Years4
ZFP36L1 Promotes Gastric Cancer Progression via Regulating JNK and p38 MAPK Signaling Pathways4
Current Prospects for Adrenocortical Carcinoma Pharmacotherapy4
Cancer Stem Cells and their Management in Cancer Therapy4
Eudragit, a Nifty Polymer for Anticancer Preparations: A Patent Review4
Lentiviral-Mediated Beclin-1 Overexpression Inhibits Cell Proliferation and Induces Autophagy of Human Esophageal Carcinoma Eca109 Cell Xenograft in Nude Mice4
Human Saliva Metabolome for Oral Lichen Planus Biomarker Identification4
A Link Between Chemical Structure and Biological Activity in Triterpenoids4
Regression of Breast Cancer Metastases Following Treatment with Irradiated SV-BR-1-GM, a GM-CSF Overexpressing Breast Cancer Cell Line: Intellectual Property and Immune Markers of Response4
Expression and Clinical Significance of Microtubule-Actin Cross-Linking Factor 1 in Serous Ovarian Cancer3
lncRNA H22954 Inhibits Angiogenesis in Acute Myeloid Leukemia through a PDGFA-dependent Mechanism3
Recent Advances in the Development of Selective Mcl-1 Inhibitors for the Treatment of Cancer (2017-Present)3
Targeted Therapies in Lung Cancers: Current Landscape and Future Prospects3
The JPJDF has Synergistic Effect with Fluoropyrimidine in the Maintenance Therapy for Metastatic Colorectal Cancer3
Alpha-solanine Anti-tumor Effects in Non-small Cell Lung Cancer Through Regulating the Energy Metabolism Pathway3
Prognostic and Therapeutic Values of Autophagy-related Genes in Triple-negative Breast Cancer3
Autophagy and Ubiquitination as Two Major Players in Colorectal Cancer: A Review on Recent Patents3
Circular RNA NF1-419 Inhibits Proliferation and Induces Apoptosis by Regulating Lipid Metabolism in Astroglioma Cells3
Gliotoxin Induced Ferroptosis by Downregulating SUV39H1 Expression in Esophageal Cancer Cells3
Prediction of Cancer Treatment Using Advancements in Machine Learning3
Network Pharmacology-based Prediction and Verification of Shikonin for Treating Colorectal Cancer3
Recent Patent-Based Perspective on Diagnostic and Therapeutic Interventions in Malignant Mesothelioma: Is Drug Repositioning Knocking on the Door?3
The Synergistic Effect of Ruthenium Complex Δ-Ru1 and Doxorubicin in a Mouse Breast Cancer Model3
Phytochemicals and Nanoparticles in the Modulation of PI3K/Akt/mTOR Kinases and its Implications in the Development and Progression of Gastrointestinal Cancers: A Review of Preclinical and Clinical Ev3
The Influence of Wuzhi Capsule on the Pharmacokinetics of Cyclophosphamide3
CRISPER/Cas in Plant Natural Product Research: Therapeutics as Anticancer and other Drug Candidates and Recent Patents3
Ultrasound-Mediated Cancer Therapeutics Delivery using Micelles and Liposomes: A Review3
Multifunctional Patented Nanotherapeutics for Cancer Intervention: 2010- Onwards3
Pemetrexed – First-Line Therapy for Non-Squamous Non-Small Cell Lung Cancer: A Review of Patent Literature3
Preface2
Chitosan - A Potential Polymer to Prepare Anticancer Drug Delivery Systems: Patent Review2
Next Generation Sequencing in the Management of Leptomeningeal Metastases of Non-Small Cell Lung Cancer: A Case Report and Literature Review2
Natural STAT3 inhibitors for cancer treatment: A Comprehensive Literature Review2
Recent Patents on Plant-Derived Nanoparticles and their Potential Application Towards Various Cancer Therapeutics2
Anticancer Potential of Aguerin B, a Sesquiterpene Lactone Isolated from Centaurea behen in Metastatic Breast Cancer Cells2
Targeting Notch Pathway in Cancer Diagnostics and Therapeutics: An Emerging Approach2
A Combined Bioinformatic and Nanoparticle-Based Study Reveal the Role of ABCG2 in the Drug Resistant Breast Cancer2
Non-histone Methylation of SET7/9 and its Biological Functions2
The Application of Nanotechnology in Immunotherapy based Combinations for Cancer Treatment2
Inhibiting the Activity of ABCG2 by KU55933 in Colorectal Cancer2
The Dichloromethane Fraction of Vernonia cinerea Impart Pro-Apoptotic, Genotoxic, Cell Cycle Arrest, and Drug Efflux Inhibitory Effects on Human Adenocarcinoma Cells2
Anti-HER2 VHH Targeted Fluorescent Liposome as Bimodal Nanoparticle for Drug Delivery and Optical Imaging2
The Efficacy and Safety of Anlotinib Alone and in Combination with Other Drugs in Previously Treated Advanced Thymic Epithelia Tumors: A Retrospective Analysis2
Pharmacological Potentials and Nutritional Values of Tropical and Subtropical Fruits of India: Emphasis on their Anticancer Bioactive Components2
Current Status and Future Perspectives on Old Drug Repurposing for Cancer Treatment2
The Anti-Tumor Mechanism and Target of Triptolide Based on Network Pharmacology and Molecular Docking2
Examining the Mechanisms of Huachansu Injection on Liver Cancer through Integrated Bioinformatics Analysis2
Increased NID1 Expression among Breast Cancer Lung Metastatic Women; A Comparative Analysis between Naive and Treated Cases2
Bourgeoning Cancer Targets2
Potential Therapeutic Application of Local Anesthetics in Cancer Treatment1
Recent Patents of Pharmaceutical Co-Crystals: Product Development on Anti-Cancer Drugs and Beyond1
β-estradiol Induces Mitochondrial Apoptosis in Cervical Cancer through the Suppression of AKT/NF-κB Signaling Pathway1
The Effect of Acetylsalicylic Acid (Asa) on the Mechanical Properties of Breast Cancer Epithelial Cells1
Altering Landscape of Cancer Vaccines: Unique Platforms, Research on Therapeutic Applications and Recent Patents1
Fatty Acid Synthase (FASN): A Patent Review Since 2016-Present1
Nanomaterials for Diagnosis and Treatment of Lung Cancer: A Review of Recent Patents1
Upregulation of M6A Reader HNRNPA2B1 Associated with Poor Prognosis and Tumor Progression in Lung Adenocarcinoma1
The Role of KCNMA1 Expression in Digestive Cancers: A Potential Prognostic Biomarker1
The Validity of Mobile Applications to Facilitate Patient Care Provided to Cancer Patients: Opportunities and Limitations1
Green Synthesized Nanoparticles as a Plausible Therapeutic Strategy Against Hepatocellular Carcinoma: An Update on its Preclinical and Clinical Relevance1
Clinical CDK2 Inhibitors: Trends to Selectivity and Efficacy1
Knockdown of RhoA Expression Reverts Enzalutamide Resistance via the p38 MAPK Pathway in Castration-resistant Prostate Cancer1
The Clinical Significance and Prognostic Value of ALDH1 Expression in Non-small Cell Lung Cancer: A Systematic Review and Meta-analysis1
The Anti-Proliferative Effect of a Newly-Produced Anti-PSCA-Peptide Antibody by Multiple Bioinformatics Tools, on Prostate Cancer Cells1
Santacruzamate A Compositions, Analogs and Methods of Use: A Patent Evaluation of WO 2014/018913 (A2)1
Comprehensive genomic analysis of puerarin in inhibiting bladder urothelial carcinoma cell proliferation and migration1
Rho GTPase Activating Protein 9 (ARHGAP9) in Human Cancers1
RNA Splicing: Basic Aspects Underlie Antitumor Targeting1
Matrix Metalloproteinase-2 (MMP-2): As an Essential Factor in Cancer Progression1
Gene Expression Network and Circ_0008012 Promote Progression in MLL/AF4 Positive Acute Lymphoblastic Leukemia1
Antibody-drug Conjugates for Breast Cancer Treatment1
Neochamaejasmine A Promotes Apoptosis and Cell Cycle Arrest in B16F10 Melanoma Cells via JNK and p38 MAPK Signaling Pathway1
Novel 4-chloro-N-phenyl Benzamide Derivatives as p38α Mitogenactivated Protein Kinase Inhibitors for Treating Cancer, COVID-19, and Other Diseases1
Monoclonal Antibodies, Bispecific Antibodies and Antibody-Drug Conjugates in Oncohematology1
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