Recent Patents on Anti-Cancer Drug Discovery

Papers
(The median citation count of Recent Patents on Anti-Cancer Drug Discovery is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
Acknowledgement to Contributors49
Acknowledgement to Reviewers43
L-Selenomethylselenocysteine Exerts Inhibitory Effects on the Progressionof Esophageal Cancer by Targeting the PI3K/AKT Signaling Pathway29
Current Prospects for Adrenocortical Carcinoma Pharmacotherapy25
Advanced Strategies of CAR-T Cell Therapy in Solid Tumors and Hematological Malignancies22
Comprehensive Genomic Analysis of Puerarin in Inhibiting Bladder Urothelial Carcinoma Cell Proliferation and Migration19
Research Progress on the Anticancer Activity of Plant Polysaccharides19
ZNF146-Mediated HMGB1-NF-κB Signaling Activation as a Therapeutic Target and Prognostic Biomarker in Osteosarcoma18
Patent Selections17
Nanomaterials for Diagnosis and Treatment of Lung Cancer: A Review of Recent Patents16
Statin Use and Hepatocellular Carcinoma Risk: A Comprehensive Meta-Analysis and Systematic Review16
Protective Assessment of Novel (BNC Formulation) against Brain Tumor16
Bioinformatic Analysis and Experimental Validation of HMGA2-AS1 as a Prognostic Biomarker Associated with Immune Infiltration in Gastric Cancer16
The Present State and Potential Applications of Artificial Intelligence in Cancer Diagnosis and Treatment15
The Prognostic Role of Interferon Gamma-inducible Protein 30 in ClearCell Renal Cell Carcinoma with Immune Infiltrates15
The Application of Nanotechnology in Immunotherapy based Combinations for Cancer Treatment15
Radiotherapy Enhancing and Radioprotective Properties of Berberine: A Systematic Review15
Oral Metronomic Chemotherapy in Nasopharyngeal Carcinoma withRadiotherapy Interruptions: A Lesson Learned from the Lockdown Due toCOVID-1914
Acknowledgement To Reviewers13
Alpha-solanine Anti-tumor Effects in Non-small Cell Lung Cancer Through Regulating the Energy Metabolism Pathway13
Network Pharmacology-based Prediction and Verification of Shikonin for Treating Colorectal Cancer13
Prognostic Value of Fatty Acid Metabolism-related Genes in Patients with Bladder Cancer13
Bioinformatics Analysis of Key Genes Associated with Resistance to the Combination of Bevacizumab and Pemetrexed Chemotherapy in Non-small Cell Lung Cancer12
Regulating Lipid Metabolism via Mitochondrial Dynamics in Tongue Squamous Cell Carcinoma Cancer Stem Cells12
Bourgeoning Cancer Targets12
Vitexin’s Role in Colon Cancer Apoptosis: AMPK/mTOR Pathway Modulation Explored Through Experimental and Computational Approaches12
Mechanisms of Anti-PD Therapy Resistance in Digestive System Neoplasms12
Integrated Single-cell and Bulk RNA Sequencing Analysis Cross Talk between Ferroptosis-related Genes and Prognosis in Oral Cavity Squamous Cell Carcinoma12
USP31 Activates the Wnt/β-catenin Signaling Pathway and Promotes Gastric Cancer Cell Proliferation, Invasion and Migration12
Survival Benefits of Ganoderma Lucidum in Early-stage Triple-negative Breast Cancer: A Real World Study12
The Causal Effects of Cholelithiasis on Acute Pancreatitis and Pancreatic Cancer: A Large Sample Size Mendelian Randomization Analysis12
Screening of Candidate Inflammatory Markers of Epithelial Cells in Hepatocellular Carcinoma based on Integration Analysis of TCGA/ICGC Databases and Single-cell Sequencing11
Predictive Modelling of Overall Survival in Adult Patients with Primary Diffuse Large B-cell Lymphoma of the Breast Using the Surveillance, Epidemiology, and End Results (SEER) Database11
Intracholecystic Papillary-tubular Neoplasm (ICPN) of the Gallbladder: A Case Report Focusing on an Unexpected Pathological Finding10
Prospective Challenges for Patenting and Clinical Trials of Anticancer Compounds from Natural Products: Coherent Review10
Circular RNA NF1-419 Inhibits Proliferation and Induces Apoptosis by Regulating Lipid Metabolism in Astroglioma Cells10
Meet the Editorial Board Member10
lncRNA H22954 Inhibits Angiogenesis in Acute Myeloid Leukemia through a PDGFA-dependent Mechanism10
Patent Selections10
Targeting the Key Signaling Pathways in Breast Cancer: From Molecular Mechanism to Therapeutic Interventions9
The m 6 A Reader IGF2BP2 Promotes Oral Squamous Cell Carcinoma Progression by Maintaining UCA1 Stability9
Natural STAT3 Inhibitors for Cancer Treatment: A Comprehensive Literature Review9
Acknowledgement to Reviewers9
Metallodrugs as Anticancer Chemotherapeutics and Diagnostic Agents: A Critical Patent Review (2010-2020)9
Construction and Identification of a Human Colorectal Adenoma Epithelial Cell Line by SV40 Large T-antigen Transfection9
SSPH I, A Novel Anti-cancer Saponin, Inhibits EMT and Invasion and Migration of NSCLC by Suppressing MAPK/ERK1/2 and PI3K/AKT/ mTOR Signaling Pathways9
Application of Nano Drug Delivery System (NDDS) in Cancer Therapy: A Perspective8
Targeted Regulation of Osteoblasts and Osteoclasts in Osteosarcoma Patients by CSF3R Receptor Inhibition of Osteolysis Caused by Tumor Inflammation Based on Transcriptional Spectrum Analysis and Drug 8
Puerarin: An Anticancer and Anti-Inflammatory Agent8
Preface8
Ubiquitination-related Gene UBTD1 Mediates Poor Prognosis of Colorectal Cancer and Affects Colorectal Cancer Cell Proliferation and Ferroptosis8
Aucubin Inhibits Liver Cancer via HMGB1-mediated Inactivation of the PI3K/AKT/mTOR Signaling Pathway7
Adverse Effects of Gefitinib on Skin and Colon in a Lung Cancer Mouse Model7
A Synergistic Combination of Oleanolic Acid and Apatinib to Enhance Antitumor Effect on Liver Cancer Cells and Protect against Hepatic Injury7
Prognostic and Therapeutic Values of Autophagy-related Genes in Triple-negative Breast Cancer7
The Synergistic Effect of Ruthenium Complex Δ-Ru1 and Doxorubicin in a Mouse Breast Cancer Model7
Exploring the Anticancer Potentials of Polyphenols: A Comprehensive Review of Patents in the Last Five Years7
Investigating the Therapeutic Potential and Molecular Mechanisms ofDaphnetin: A Comprehensive Review7
The FJQR Has Synergistic Effect with Fluoropyrimidine in the Maintenance Treatment for HER-2 Negative Gastric Cancer7
Fatty Acid Synthase (FASN): A Patent Review Since 2016-Present7
Patent Selections7
Advances in the Treatment of Chronic Myeloid Leukemia7
Development of a Novel Lipid Metabolism-related Gene Prognostic Signature for Patients with Colorectal Cancer6
UBE2L3 Suppresses Oxidative Stress-regulated Necroptosis to Accelerate Osteosarcoma Progression6
Patent Selections6
Targeting Notch Pathway in Cancer Diagnostics and Therapeutics: An Emerging Approach6
pH-responsive Sulfated Hyaluronic Acid Nanoparticles Targeting Tumor Cells and CAFs for the Treatment of Breast Cancer6
Nano-carriers based Approaches Loaded with Herbal Bioactive Compounds for the Treatment of Cancer: Recent Updates and Future Prospects5
KRAS Pathways: A Potential Gateway for Cancer Therapeutics and Diagnostics5
Structure-Based Virtual Screening of Novel FOXM1 Inhibitors as Potential Compounds for Glioblastoma Treatment5
Morusin Suppresses Pancreatic Cancer Cell Proliferation and Migrationby Targeting SLC6A12 to Inhibit NF-κB and β-catenin SignalingPathways5
LMNB1 and LMNB2 as Prognostic Risk Factors in Hepatocellular Carcinoma: Therapeutic Potential of GSK461364 via Downregulation of LMNB1 and LMNB2 Expression5
Patents on PARP-1 Inhibitors for the Management of Cancer from 2017-20235
LINC00936/microRNA-221-3p Regulates Tumor Progression in Ovarian Cancer by Interacting with LAMA35
Exploring the Molecular Mechanisms and Biological Effects of CELF2 in the Development of Gastric Cancer5
Daidzein and Chicory Extract Arrest the Cell Cycle via Inhibition of Cyclin D/CDK4 and Cyclin A/CDK2 Gene Expression in Hepatocellular Carcinoma5
Epigallocatechin Gallate Derivative Y 6 Reverses Oxaliplatin Resistance in Hepatocellular Carcinoma via Targeting the MiR-338-3p/HIF-1α/TWIST Axis to5
Eukaryotic Initiation Factor 3C Can Affect the Proliferation and Invasion of Ovarian Cancer by Regulating the p53 Signalling Pathway4
Strategies for Developing Cancer Theranostics Approaches4
Ribosome-inactivating Protein MAP30 Isolated from Momordica Charantia L. Induces Apoptosis in Hepatocellular Carcinoma Cells4
Identification of Breast Cancer Immune-related Prognostic Characteristics in Tumor Microenvironment4
Antibody-drug Conjugates for Breast Cancer Treatment4
Targeting Ferroptosis as a New Approach for Radiation Protection and Mitigation4
Patent Selections4
TGF-β Score based on Silico Analysis can Robustly Predict Prognosis and Immunological Characteristics in Lower-grade Glioma: The Evidence from Multicenter Studies4
ZFP36L1 Promotes Gastric Cancer Progression via Regulating JNK and p38 MAPK Signaling Pathways4
Exosome-Derived Cargos in Immune Microenvironment in Esophageal Carcinoma: A Mini-Review4
Altering Landscape of Cancer Vaccines: Unique Platforms, Research on Therapeutic Applications and Recent Patents4
Nanotechnology a Boon for Colorectal Cancer Treatment3
Meet the Editorial Board Member3
New 1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-2-phenylisoquinoline-1(2H)-ones as Phosphoinositide 3-kinase Inhibitors for Treating Cancer and Other Diseases3
Adhesin Component Member STAG2 Enhances Cisplatin Tolerance in Colorectal Cancer Cells through the Epithelial-mesenchymal Transition Pathway3
Meet the Associate Editorial Board Member3
Updated Progress on Mass Spectrometry Imaging and its Application in Cancer Treatment and Drug Discovery3
1,3,4-Oxadiazoles as Anticancer Agents: A Review3
Differentiation of Acute Leukemia Cells Including Cells with MLL-AF4 Rearrangements Induced by Jiyuan Oridonin A3
Patent Selections3
Recent Patents of Pharmaceutical Co-Crystals: Product Development on Anti-Cancer Drugs and Beyond3
Patent Selections3
Unveiling miR-1468-5p: A New Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma3
The Impact of Polyphenolics in the Management of Breast Cancer: Mechanistic Aspects and Recent Patents3
Green Synthesized Nanoparticles as a Plausible Therapeutic Strategy Against Hepatocellular Carcinoma: An Update on its Preclinical and Clinical Relevance3
β-estradiol Induces Mitochondrial Apoptosis in Cervical Cancer through the Suppression of AKT/NF-κB Signaling Pathway3
A Single-arm, Open-label, Phase Ib Clinical Study Evaluating the Efficacy and Safety of Durvalumab in Combination with Albumin-bound Paclitaxel and Carboplatin as Neoadjuvant Therapy for Resectable St3
Competitive Effect of Overexpressed C-terminal of Snail-1 (CSnail) in Control of the Growth and Metastasis of Melanoma Cells3
The Role of KCNMA1 Expression in Digestive Cancers: A Potential Prognostic Biomarker3
Dahuang Zhechong Pill Combined with TNS4 Silencing Inhibits theNF-κB/VEGF Pathway To Slow Down The Progression Of PancreaticCancer2
Increased SLC7A3 Expression Inhibits Tumor Cell Proliferation and Predicts a Favorable Prognosis in Breast Cancer2
The Non-hodgkin Lymphoma Treatment and Side Effects: A Systematic Review and Meta-analysis2
Roles of TEAD Transcription Factors and their Coactivators in the Progression and Metastasis of Cancers2
Tracing the Technological Trajectory of CAR-T Cell Therapy in Cancer Treatment through Patent Analysis2
The Clinical Significance and Prognostic Value of ALDH1 Expression in Non-small Cell Lung Cancer: A Systematic Review and Meta-analysis2
Preclinical Effects of Melatonin on the Development of Ehrlich's Tumor: A Biochemical, Cognitive, and Molecular Approach2
Transdermal Drug Delivery: A Step towards Treatment of Cancer2
Development and Evaluation of a Novel Hyaluronic Acid and Chitosan-modified Phytosome for Co-delivery of Oxymatrine and Glycyrrhizin for Combination Therapy2
Inhibiting the Activity of ABCG2 by KU55933 in Colorectal Cancer2
From Multiple Myeloma to Acute Myeloid Leukemia: A Case Report of a 61-year-old Woman after 8 Years of Chemotherapy and Immunotherapy2
TENT5A Increases Glioma Malignancy and Promotes its Progression2
Sema3A Affect Osteolytic Bone Metastasis of Non-small Cell Lung Cancer2
Identification of Immune Infiltration-related Molecular Features in Ovarian Cancer Patients and Experimental Validation of Immune Response Molecular Mechanisms through Integrated WGCNA, Machine Learni2
West African Medicinal Plant Substances and Molecules ActivitiesAgainst Viral Hepatitis B and Hepatocellular Carcinoma2
Metal Nanoparticles as Emerging Drug Candidates in the Management of Cancers and Microbial Infectious Diseases2
Downregulation of miRNA-14669 Reverses Vincristine Resistance in Colorectal Cancer Cells through PI3K/AKT Signaling Pathway2
Nano-Based Drug Delivery of Anticancer Chemotherapeutic Drugs Targeting Breast Cancer2
The Patent Landscape of BRAF Target and KRAS Target2
Neochamaejasmine A Promotes Apoptosis and Cell Cycle Arrest in B16F10 Melanoma Cells via JNK and p38 MAPK Signaling Pathway2
Advances in Artemisinin-based Therapies: Innovations in Synthesis, Drug Delivery, and Expanding Therapeutic Applications2
A Link Between Chemical Structure and Biological Activity in Triterpenoids2
Phytochemicals and Nanoparticles in the Modulation of PI3K/Akt/mTOR Kinases and its Implications in the Development and Progression of Gastrointestinal Cancers: A Review of Preclinical and Clinical Ev2
Patent Selections2
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