OOIR: Observatory of International Research

Papers

(The TQCC of Molecular Oncology is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Targeting immunogenic cell death in cancer	471
Elesclomol induces copper‐dependent ferroptosis in colorectal cancer cells via degradation of ATP7A	148
Clinical utility of circulating tumor cells: an update	120
Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS–mitochondrial fission–mitophagy axis	96
Dual inhibition of TGF‐β and PD‐L1: a novel approach to cancer treatment	70
Overcoming the senescence‐associated secretory phenotype (SASP): a complex mechanism of resistance in the treatment of cancer	70
Global mapping of cancers: The Cancer Genome Atlas and beyond	68
iRGD‐modified exosomes effectively deliver CPT1A siRNA to colon cancer cells, reversing oxaliplatin resistance by regulating fatty acid oxidation	60
LncRNA NKX2‐1‐AS1 promotes tumor progression and angiogenesis via upregulation of SERPINE1 expression and activation of the VEGFR‐2 signaling pathway in gastric cancer	58
Cancer diagnostics based on plasma protein biomarkers: hard times but great expectations	57
METTL3/YTHDF2 m6A axis accelerates colorectal carcinogenesis through epigenetically suppressing YPEL5	57
Enhancing cancer‐associated fibroblast fatty acid catabolism within a metabolically challenging tumor microenvironment drives colon cancer peritoneal metastasis	55
Cellular senescence and the tumour microenvironment	54
Doxorubicin‐induced senescence promotes stemness and tumorigenicity in EpCAM−/CD133− nonstem cell population in hepatocellular carcinoma cell line, HuH‐7	52
FOXD1‐AS1 regulates FOXD1 translation and promotes gastric cancer progression and chemoresistance by activating the PI3K/AKT/mTOR pathway	51
Immune response drives outcomes in prostate cancer: implications for immunotherapy	51
Early assessment of circulating tumor DNA after curative‐intent resection predicts tumor recurrence in early‐stage and locally advanced non‐small‐cell lung cancer	49
Detection and relevance of epigenetic markers on ctDNA: recent advances and future outlook	49
Tobacco control policies in the 21st century: achievements and open challenges	46
Targeted inhibition of STAT3 induces immunogenic cell death of hepatocellular carcinoma cells via glycolysis	45
Fragment‐based drug discovery—the importance of high‐quality molecule libraries	44
Circulating platelets as liquid biopsy sources for cancer detection	41
Circulating exosomalmiR‐363‐5pinhibits lymph node metastasis by downregulatingPDGFBand serves as a potential noninvasive biomarker for breast cancer	40
Circ_0008039 supports breast cancer cell proliferation, migration, invasion, and glycolysis by regulating the miR‐140‐3p/SKA2 axis	39
Deubiquitinase PSMD14 promotes ovarian cancer progression by decreasing enzymatic activity of PKM2	39

Circulating tumor cell profiling for precision oncology	39
A novel prognostic mRNA/miRNA signature for esophageal cancer and its immune landscape in cancer progression	38
TGFBI modulates tumour hypoxia and promotes breast cancer metastasis	38
Lipidomic profiling of exosomes from colorectal cancer cells and patients reveals potential biomarkers	37
Autophagy at the intersection of aging, senescence, and cancer	37
Targeting senescence as an anticancer therapy	36
MYC and therapy resistance in cancer: risks and opportunities	36
A novel cell‐free DNA methylation‐based model improves the early detection of colorectal cancer	36
Protein palmitoylation in cancer: molecular functions and therapeutic potential	35
Resistance to DNA repair inhibitors in cancer	35
Extracellular vesicles and oncogenic signaling	35
FOXM1D potentiates PKM2‐mediated tumor glycolysis and angiogenesis	35
SENP3 loss promotes M2 macrophage polarization and breast cancer progression	34
Periostin⁺cancer‐associated fibroblasts promote lymph node metastasis by impairing the lymphatic endothelial barriers in cervical squamous cell carcinoma	34
LncRNA SOX2‐OT regulates AKT/ERK and SOX2/GLI‐1 expression, hinders therapy, and worsens clinical prognosis in malignant lung diseases	33
RETRACTED: CircRNA EPHB4 modulates stem properties and proliferation of gliomas via sponging miR‐637 and up‐regulating SOX10	33
Irradiation‐induced polyploid giant cancer cells are involved in tumor cell repopulation via neosis	32
Metabolomic profile of cancer stem cell‐derived exosomes from patients with malignant melanoma	32
SMARCA4 mutations in KRAS‐mutant lung adenocarcinoma: a multi‐cohort analysis	32
LAMC1 upregulation via TGFβ induces inflammatory cancer‐associated fibroblasts in esophageal squamous cell carcinoma via NF‐κB–CXCL1–STAT3	31
Multifaceted activities of transcription factor EB in cancer onset and progression	31
Targeting KRAS mutant lung cancer: light at the end of the tunnel	30
Long noncoding RNA DANCR confers cytarabine resistance in acute myeloid leukemia by activating autophagy via the miR‐874‐3P/ATG16L1 axis	30
Vitamin D supplementation to the older adult population in Germany has the cost‐saving potential of preventing almost 30 000 cancer deaths per year	30
EHMT1 knockdown induces apoptosis and cell cycle arrest in lung cancer cells by increasing CDKN1A expression	30
Circular RNA profiling identifies circ102049 as a key regulator of colorectal liver metastasis	29
Autophagy inhibits cancer stemness in triple‐negative breast cancer via miR‐181a‐mediated regulation of ATG5 and/or ATG2B	28
FUBP1 promotes colorectal cancer stemness and metastasis via DVL1‐mediated activation of Wnt/β‐catenin signaling	28
Fluid shear stress activates YAP to promote epithelial–mesenchymal transition in hepatocellular carcinoma	28
Cancer‐associated fibroblasts educate normal fibroblasts to facilitate cancer cell spreading and T‐cell suppression	28
Single‐cell transcriptomics reveal the intratumoral landscape of infiltrated T‐cell subpopulations in oral squamous cell carcinoma	28
Early detection of hepatocellular carcinoma via liquid biopsy: panel of small extracellular vesicle‐derived long noncoding RNAs identified as markers	28
Histological and mutational profile of diffuse gastric cancer: current knowledge and future challenges	27
Autophagy activation and SREBP‐1 induction contribute to fatty acid metabolic reprogramming by leptin in breast cancer cells	27
Cancer‐associated fibroblast migration in non‐small cell lung cancers is modulated by increased integrin α11 expression	26
Deubiquitinase OTUD6A promotes proliferation of cancer cells via regulating Drp1 stability and mitochondrial fission	26
The lncRNA ‘UCA1’ modulates the response to chemotherapy of ovarian cancer through direct binding to miR‐27a‐5p and control of UBE2N levels	26
DNA repair as a shared hallmark in cancer and ageing	25
The evolutionarily conserved long non‐coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms	25
Constitutive activation of integrin αvβ3 contributes to anoikis resistance of ovarian cancer cells	25
Serial circulating tumor DNA to predict early recurrence in patients with hepatocellular carcinoma: a prospective study	25
Mitochondrial DNA mutations in ageing and cancer	25
Gene expression profiles of breast cancer metastasis according to organ site	25
High‐throughput proteomics of breast cancer interstitial fluid: identification of tumor subtype‐specific serologically relevant biomarkers	24
Multiomics integrative analysis reveals antagonistic roles of CBX2 and CBX7 in metabolic reprogramming of breast cancer	24
Platycodin D inhibits autophagy and increases glioblastoma cell death via LDLR upregulation	24
Phosphorylation of the androgen receptor at Ser81 is co‐sustained by CDK1 and CDK9 and leads to AR‐mediated transactivation in prostate cancer	24
Discovery and validation of extracellular vesicle‐associated miRNAs as noninvasive detection biomarkers for early‐stage non‐small‐cell lung cancer	24
Oncogenic KRAS mutations enhance amino acid uptake by colorectal cancer cells via the hippo signaling effector YAP1	24
DCZ0415, a small‐molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β‐catenin pathway in colorectal cancer	24

Downregulation of adipose triglyceride lipase by EB viral‐encoded LMP2A links lipid accumulation to increased migration in nasopharyngeal carcinoma	24
The miR‐19b‐3p‐MAP2K3‐STAT3 feedback loop regulates cell proliferation and invasion in esophageal squamous cell carcinoma	24
FKBP51 and FKBP52 regulate androgen receptor dimerization and proliferation in prostate cancer cells	23
Breast cancer metastasis: immune profiling of lymph nodes reveals exhaustion of effector T cells and immunosuppression	23
Molecular profiling of long‐term responders to immune checkpoint inhibitors in advanced non‐small cell lung cancer	23
The genetic landscape of metaplastic breast cancers and uterine carcinosarcomas	23
Mutated circulating tumor DNA as a liquid biopsy in lung cancer detection and treatment	23
Occupational cancer burden: the contribution of exposure to process‐generated substances at the workplace	23
Clinical potential of circulating free DNA and circulating tumour cells in patients with metastatic non‐small‐cell lung cancer treated with pembrolizumab	23
Lipocalin 2 promotes inflammatory breast cancer tumorigenesis and skin invasion	23
Long non‐coding RNA RACGAP1P promotes breast cancer invasion and metastasis via miR‐345‐5p/RACGAP1‐mediated mitochondrial fission	23
CircATRNL1 activates Smad4 signaling to inhibit angiogenesis and ovarian cancer metastasis via miR‐378	22
A novel circular RNA, hsa_circ_0030998 suppresses lung cancer tumorigenesis and Taxol resistance by sponging miR‐558	22
Circulating tumor DNA as a biomarker for monitoring early treatment responses of patients with advanced lung adenocarcinoma receiving immune checkpoint inhibitors	22
Viruses in colorectal cancer	22
The PI3K/mTOR inhibitor Gedatolisib eliminates dormant breast cancer cells in organotypic culture, but fails to prevent metastasis in preclinical settings	22
Role of aneuploid circulating tumor cells and CD31⁺ circulating tumor endothelial cells in predicting and monitoring anti‐angiogenic therapy efficacy in advanced NSCLC	21
Patient‐derived organoids as a preclinical platform for precision medicine in colorectal cancer	21
Integrating bulk and single‐cell RNA sequencing reveals cellular heterogeneity and immune infiltration in hepatocellular carcinoma	21
Blood DNA methylation profiles improve breast cancer prediction	21
A novel prognostic model based on four circulating miRNA in diffuse large B‐cell lymphoma: implications for the roles of MDSC and Th17 cells in lymphoma progression	21
Genomic characterization of small cell carcinomas of the uterine cervix	20
BAP1 suppresses prostate cancer progression by deubiquitinating and stabilizing PTEN	20
The KRAS/Lin28B axis maintains stemness of pancreatic cancer cells via the let‐7i/TET3 pathway	20
DDRugging glioblastoma: understanding and targeting the DNA damage response to improve future therapies	20
Neurotensin receptor 1 signaling promotes pancreatic cancer progression	20
BMP9‐ID1 signaling promotes EpCAM‐positive cancer stem cell properties in hepatocellular carcinoma	20
PD‐1‐induced T cell exhaustion is controlled by a Drp1‐dependent mechanism	20
Integrative analysis of gut microbiome and host transcriptomes reveals associations between treatment outcomes and immunotherapy‐induced colitis	20
Cancer‐associated fibroblasts promote tumor progression by lncRNA‐mediated RUNX2/GDF10 signaling in oral squamous cell carcinoma	19
The sculpting of somatic mutational landscapes by evolutionary forces and their impacts on aging‐related disease	19
Comprehensive cross‐platform comparison of methods for non‐invasive EGFR mutation testing: results of the RING observational trial	19
Artificial intelligence in cancer research: learning at different levels of data granularity	19
ST6GalNAc‐I promotes lung cancer metastasis by altering MUC5AC sialylation	19
Pan‐cancer analysis reveals sex‐specific signatures in the tumor microenvironment	19
Anti‐Chi3L1 antibody suppresses lung tumor growth and metastasis through inhibition of M2 polarization	19
HRD1 inhibits fatty acid oxidation and tumorigenesis by ubiquitinating CPT2 in triple‐negative breast cancer	19
Benchmarking HLA genotyping and clarifying HLA impact on survival in tumor immunotherapy	19
EWI‐2 controls nucleocytoplasmic shuttling of EGFR signaling molecules and miRNA sorting in exosomes to inhibit prostate cancer cell metastasis	18
Immune modulation underpins the anti‐cancer activity of HDAC inhibitors	18
Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1‐driven acute lymphoblastic leukemia	18
Effect of p53 and its N‐terminally truncated isoform, Δ40p53, on breast cancer migration and invasion	18
Widespread overexpression from the four DNA hypermethylated HOX clusters in aggressive (IDHwt) glioma is associated with H3K27me3 depletion and alternative promoter usage	18
The ZEB2‐dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer	18
Therapeutic targeting with DABIL‐4 depletes myeloid suppressor cells in 4T1 triple‐negative breast cancer model	18
ERK signaling controls productive HIF‐1 binding to chromatin and cancer cell adaptation to hypoxia through HIF‐1α interaction with NPM1	18
Promoter methylation of DNA homologous recombination genes is predictive of the responsiveness to PARP inhibitor treatment in testicular germ cell tumors	18
KMT2C promoter methylation in plasma‐circulating tumor DNA is a prognostic biomarker in non‐small cell lung cancer	18
SIK2 represses AKT/GSK3β/β‐catenin signaling and suppresses gastric cancer by inhibiting autophagic degradation of protein phosphatases	18
Secretogranin II impairs tumor growth and angiogenesis by promoting degradation of hypoxia‐inducible factor‐1α in colorectal cancer	18
T2R bitter taste receptors regulate apoptosis and may be associated with survival in head and neck squamous cell carcinoma	17
SF3B1 mutation in pancreatic cancer contributes to aerobic glycolysis and tumor growth through a PP2A–c‐Myc axis	17
Acquired small cell lung cancer resistance to Chk1 inhibitors involves Wee1 up‐regulation	17
Stratification of follicular thyroid tumours using data‐independent acquisition proteomics and a comprehensive thyroid tissue spectral library	17
Sphingolipid metabolism in the development and progression of cancer: one cancer's help is another's hindrance	17
NOX4 regulates TGFβ‐induced proliferation and self‐renewal in glioblastoma stem cells	17
Molecular characteristics and tumorigenicity of ascites‐derived tumor cells: mitochondrial oxidative phosphorylation as a novel therapy target in ovarian cancer	17
Long non‐coding RNA SNHG1 stimulates ovarian cancer progression by modulating expression of miR‐454 and ZEB1	17
Human intestinal and circulating invariant natural killer T cells are cytotoxic against colorectal cancer cells via the perforin–granzyme pathway	17
Genome‐scale CRISPR screening identifies cell cycle and protein ubiquitination processes as druggable targets for erlotinib‐resistant lung cancer	17
Mitochondrial STAT3 regulates antioxidant gene expression through complex I‐derived NAD in triple negative breast cancer	17
microRNA‐99a‐5p induces cellular senescence in gemcitabine‐resistant bladder cancer by targeting SMARCD1	17
Cyr61 from adipose‐derived stem cells promotes colorectal cancer metastasis and vasculogenic mimicry formation via integrin α_Vβ₅	17
EML4‐ALK biology and drug resistance in non‐small cell lung cancer: a new phase of discoveries	17
NGS‐based liquid biopsy profiling identifies mechanisms of resistance to ALK inhibitors: a step toward personalized NSCLC treatment	17
Nicotinamide (niacin) supplement increases lipid metabolism and ROS‐induced energy disruption in triple‐negative breast cancer: potential for drug repositioning as an anti‐tumor agent	17
Characterization of fragment sizes, copy number aberrations and 4‐mer end motifs in cell‐free DNA of hepatocellular carcinoma for enhanced liquid biopsy‐based cancer detection	17
MicroRNA expression profiling with a droplet digital PCR assay enables molecular diagnosis and prognosis of cancers of unknown primary	17
imPlatelet classifier: image‐converted RNA biomarker profiles enable blood‐based cancer diagnostics	17
A small molecule targeting CHI3L1 inhibits lung metastasis by blocking IL‐13Rα2‐mediated JNK‐AP‐1 signals	17
MIB1 upregulates IQGAP1 and promotes pancreatic cancer progression by inducing ST7 degradation	17
Metagenomic analysis of primary colorectal carcinomas and their metastases identifies potential microbial risk factors	17
Cotargeting of miR‐126‐3p and miR‐221‐3p inhibits PIK3R2 and PTEN, reducing lung cancer growth and metastasis by blocking AKT and CXCR4 signalling	17
Mechanistic insights into p53‐regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cells	16
USP35 mitigates endoplasmic reticulum stress‐induced apoptosis by stabilizing RRBP1 in non‐small cell lung cancer	16
Challenges and solutions to embed cancer survivorship research and innovation within the EU Cancer Mission	16
Multiplex RNA‐based detection of clinically relevant MET alterations in advanced non‐small cell lung cancer	16
Assessment of tumor burden and response to therapy in patients with colorectal cancer using a quantitative ctDNA test for methylated BCAT1/IKZF1	16
ALKBH1‐mediated m¹A demethylation of METTL3mRNA promotes the metastasis of colorectal cancer by downregulating SMAD7 expression	16
Targeting the DNA damage response and repair in cancer through nucleotide metabolism	16

Small extracellular vesicles from malignant ascites of patients with advanced ovarian cancer provide insights into the dynamics of the extracellular matrix	16
Extracellular LGALS3BP: a potential disease marker and actionable target for antibody–drug conjugate therapy in glioblastoma	16
Metastatic colorectal cancer and type 2 diabetes: prognostic and genetic interactions	16
SLUG‐related partial epithelial‐to‐mesenchymal transition is a transcriptomic prognosticator of head and neck cancer survival	16
Artificial intelligence‐driven consensus gene signatures for improving bladder cancer clinical outcomes identified by multi‐center integration analysis	16
Molecular genomic features associated with in vitro response of the NCI‐60 cancer cell line panel to natural products	16
Integrative analysis of immune‐related multi‐omics profiles identifies distinct prognosis and tumor microenvironment patterns in osteosarcoma	16
Combining variant detection and fragment length analysis improves detection of minimal residual disease in postsurgery circulating tumour DNA of stage II–IIIA NSCLC patients	16
DNA methylation markers have universal prognostic value for anal cancer risk in HIV‐negative and HIV‐positive individuals	15
The RNA‐binding protein MEX3A is a prognostic factor and regulator of resistance to gemcitabine in pancreatic ductal adenocarcinoma	15
VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer	15
Targeting the ubiquitin‐proteasome system in a pancreatic cancer subtype with hyperactive MYC	15
Novel CTRP8‐RXFP1‐JAK3‐STAT3 axis promotes Cdc42‐dependent actin remodeling for enhanced filopodia formation and motility in human glioblastoma cells	15
RETRACTED: MeCP2 drives hepatocellular carcinoma progression via enforcing HOXD3 promoter methylation and expression through the HB‐EGF/EGFR pathway	15
Cancer outcomes research—a European challenge: measures of the cancer burden	15
RNA m⁶Amethylation in cancer	15
Development and initial clinical testing of a multiplexed circulating tumor cell assay in patients with clear cell renal cell carcinoma	15
Genomic and pathological heterogeneity in clinically diagnosed small cell lung cancer in never/light smokers identifies therapeutically targetable alterations	15
Dynamic monitoring of PD‐L1 and Ki67 in circulating tumor cells of metastatic non‐small cell lung cancer patients treated with pembrolizumab	15
JNK‐mediated Ser27 phosphorylation and stabilization of SIRT1 promote growth and progression of colon cancer through deacetylation‐dependent activation of Snail	15
Targeted inhibition of ERα signaling and PIP5K1α/Akt pathways in castration‐resistant prostate cancer	15
Targeting of lactate dehydrogenase C dysregulates the cell cycle and sensitizes breast cancer cells to DNA damage response targeted therapy	15
USP22‐mediated deubiquitination of PTEN inhibits pancreatic cancer progression by inducing p21 expression	15
Co‐occurrence of BAP1 and SF3B1 mutations in uveal melanoma induces cellular senescence	15
Detection of gene mutations and gene–gene fusions in circulating cell‐free DNA of glioblastoma patients: an avenue for clinically relevant diagnostic analysis	15
Tspan5 promotes epithelial–mesenchymal transition and tumour metastasis of hepatocellular carcinoma by activating Notch signalling	15
KSR induces RAS‐independent MAPK pathway activation and modulates the efficacy of KRAS inhibitors	15
Lineage‐specific mechanisms and drivers of breast cancer chemoresistance revealed by 3D biomimetic culture	14
Prolonged estrogen deprivation triggers a broad immunosuppressive phenotype in breast cancer cells	14
Anti‐pyroptotic function of TGF‐β is suppressed by a synthetic dsRNA analogue in triple negative breast cancer cells	14
Loss of GABARAPL1 confers ferroptosis resistance to cancer stem‐like cells in hepatocellular carcinoma	14
The pleiotropic roles of circular and long noncoding RNAs in cutaneous melanoma	14
Interaction of transcription factor AP‐2 gamma with proto‐oncogene PELP1 promotes tumorigenesis by enhancing RET signaling	14
FET fusion oncoproteins interact with BRD4 and SWI/SNF chromatin remodelling complex subtypes in sarcoma	14
Serial monitoring of genomic alterations in circulating tumor cells of ER‐positive/HER2‐negative advanced breast cancer: feasibility of precision oncology biomarker detection	14
TLK1‐mediated MK5‐S354 phosphorylation drives prostate cancer cell motility and may signify distinct pathologies	14
Frequency, underdiagnosis, and heterogeneity of epidermal growth factor receptor exon 20 insertion mutations using real‐world genomic datasets	14
Tetraspanin 1 promotes endometriosis leading to ovarian clear cell carcinoma	14
Tieing together loose ends: telomere instability in cancer and aging	14
5‐Hydroxymethylcytosine signature in circulating cell‐free DNA as a potential diagnostic factor for early‐stage colorectal cancer and precancerous adenoma	14
Cerebrospinal fluid circulating tumor DNA depicts profiling of brain metastasis in NSCLC	14
SIK2 promotes ovarian cancer cell motility and metastasis by phosphorylating MYLK	14
A novel anti‐c‐Kit antibody–drug conjugate to treat wild‐type and activating‐mutant c‐Kit‐positive tumors	13
Precision N‐glycoproteomics reveals elevated LacdiNAc as a novel signature of intrahepatic cholangiocarcinoma	13
Multiplexed digital spatial profiling of invasive breast tumors from Black and White women	13
Genome‐wide DNA methylation profiling and identification of potential pan‐cancer and tumor‐specific biomarkers	13
Systematic exploration of the underlying mechanism of gemcitabine resistance in pancreatic adenocarcinoma	13
Regulation of MRE11A by UBQLN4 leads to cisplatin resistance in patients with esophageal squamous cell carcinoma	13
Ubiquitin‐specific peptidase 39 promotes human glioma cells migration and invasion by facilitating ADAM9 mRNA maturation	13
Exploring hTERT promoter methylation in cutaneous T‐cell lymphomas	13
The promises and challenges of early non‐small cell lung cancer detection: patient perceptions, low‐dose CT screening, bronchoscopy and biomarkers	13
DRP1 contributes to head and neck cancer progression and induces glycolysis through modulated FOXM1/MMP12 axis	13
The melanoma brain metastatic microenvironment: aldolase C partakes in shaping the malignant phenotype of melanoma cells – a case of inter‐tumor heterogeneity	13
Repression of the stress granule protein G3BP2 inhibits immune checkpoint molecule PD‐L1	13
WBP2 promotes BTRC mRNA stability to drive migration and invasion in triple‐negative breast cancer via NF‐κB activation	13
Predicting osimertinib‐treatment outcomes through EGFR mutant‐fraction monitoring in the circulating tumor DNA of EGFR T790M‐positive patients with non‐small cell lung cancer (WJOG8815L)	13
A cancer‐associated CDKN1B mutation induces p27 phosphorylation on a novel residue: a new mechanism for tumor suppressor loss‐of‐function	12
Liquid biopsy: from discovery to clinical implementation	12
PDSS2‐Del2, a new variant of PDSS2, promotes tumor cell metastasis and angiogenesis in hepatocellular carcinoma via activating NF‐κB	12
Cost‐effectiveness of precision diagnostic testing for precision medicine approaches against non‐small‐cell lung cancer: A systematic review	12
NNK from tobacco smoking enhances pancreatic cancer cell stemness and chemoresistance by creating a β2AR‐Akt feedback loop that activates autophagy	12
Elucidating tumour‐associated microglia/macrophage diversity along glioblastoma progression and underACOD1deficiency	12
Reciprocal epigenetic remodeling controls testicular cancer hypersensitivity to hypomethylating agents and chemotherapy	12
Genomic and prognostic heterogeneity among RAS/BRAF^V600E/TP53 co‐mutated resectable colorectal liver metastases	12
miR‐126 downregulates CXCL12 expression in intestinal epithelial cells to suppress the recruitment and function of macrophages and tumorigenesis in a murine model of colitis‐associated colorect	12
The ERRα–VDR axis promotes calcitriol degradation and estrogen signaling in breast cancer cells, while VDR‐CYP24A1‐ERRα overexpression correlates with poor prognosis in patients with basal‐like breast	12
LncRNA miR205HG hinders HNRNPA0 translation: anti‐oncogenic effects in esophageal carcinoma	12
Digital multiplexed analysis of circular RNAs in FFPE and fresh non‐small cell lung cancer specimens	12
Playing cancer at its own game: activating mitogenic signaling as a paradoxical intervention	12
Small nucleolar RNA SNORA71A promotes epithelial‐mesenchymal transition by maintaining ROCK2 mRNA stability in breast cancer	12
Insights into the molecular profiles of adult and paediatric acute myeloid leukaemia	12
Downregulation of m⁶A writer complex member METTL14 in bladder urothelial carcinoma suppresses tumor aggressiveness	12
A novel long noncoding RNA, TMEM92‐AS1, promotes gastric cancer progression by binding to YBX1 to mediate CCL5	12
The RNA‐helicase DDX21 upregulates CEP55 expression and promotes neuroblastoma	12
Identification of RUNX1T1 as a potential epigenetic modifier in small‐cell lung cancer	12
Intrinsic and acquired drug resistance to LSD1 inhibitors in small cell lung cancer occurs through a TEAD4‐driven transcriptional state	12
UBE2T promotes β‐catenin nuclear translocation in hepatocellular carcinoma through MAPK/ERK‐dependent activation	12
Epigenetic regulator BMI1 promotes alveolar rhabdomyosarcoma proliferation and constitutes a novel therapeutic target	11
Pre‐ and post‐treatment blood‐based genomic landscape of patients with ROS1 or NTRK fusion‐positive solid tumours treated with entrectinib	11
Clinical significance of circulating tumor cells and cell‐free DNA in pediatric rhabdomyosarcoma	11
Liquid biopsy reveals KLK3 mRNA as a prognostic marker for progression free survival in patients with metastatic castration‐resistant prostate cancer undergoing first‐line abiraterone acetate and pred	11
Clinical significance of FAT1 gene mutation and mRNA expression in patients with head and neck squamous cell carcinoma	11
CDH6‐activated αIIbβ3 crosstalks with α2β1 to trigger cellular adhesion and invasion in metastatic ovarian and renal cancers	11
Discovery of novel DNA methylation biomarkers for non‐invasive sporadic breast cancer detection in the Latino population	11
hnRNP‐A1 binds to the IRES of MELOE‐1 antigen to promote MELOE‐1 translation in stressed melanoma cells	11
FANCD2 limits acetaldehyde‐induced genomic instability during DNA replication in esophageal keratinocytes	11
Sex disparity in acute myeloid leukaemia with FLT3 internal tandem duplication mutations: implications for prognosis	11
JAK–STAT signalling shapes the NF‐κB response in CLL towards venetoclax sensitivity or resistance via Bcl‐XL	11
Monitoring levels of circulating cell‐free DNA in patients with metastatic colorectal cancer as a potential biomarker of responses to regorafenib treatment	11
Genome‐wide analysis of DNA methylation identifies the apoptosis‐related gene UQCRH as a tumor suppressor in renal cancer	11
The signal transducer CD24 suppresses the germ cell program and promotes an ectodermal rather than mesodermal cell fate in embryonal carcinomas	11
BRCA1 promoter hypermethylation on circulating tumor DNA correlates with improved survival of patients with ovarian cancer	11
Targeting mitochondrial respiration and the BCL2 family in high‐grade MYC‐associated B‐cell lymphoma	11
p53 mutations define the chromatin landscape to confer drug tolerance in pancreatic cancer	11
Precision medicine‐based therapies in advanced colorectal cancer: The University of California San Diego Molecular Tumor Board experience	11