Molecular Oncology

Article	Citations
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Issue Information	119
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Corrigendum to: Small proline‐rich repeat protein 3 enhances the sensitivity of esophageal cancer cells in response to DNA damage‐induced apoptosis	81
An arms‐race against resistance: leukemic stem cells and lineage plasticity	76
Correction to “SPT6 recruits SND1 to co‐activate human telomerase reverse transcriptase to promote colon cancer progression”	74
Gene signature predicting recurrence in oral squamous cell carcinoma is characterized by increased oxidative phosphorylation	72
PoDCall: a robust tool for automated droplet classification in DNA‐methylation droplet digital PCR	69
Precision Cancer Medicine 2.0—Oncology in the postgenomic era	65
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Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma	52
Correction to “Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition”	48
The selenoenzyme type I iodothyronine deiodinase: a new tumor suppressor in ovarian cancer	48
Evaluation of two new highly multiplexed PCR assays as an alternative to next‐generation sequencing for IDH1/2 mutation detection	46
Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo	46
TGFβ selects for pro‐stemness over pro‐invasive phenotypes during cancer cell epithelial–mesenchymal transition	42
Expanding a precision medicine platform for malignant peripheral nerve sheath tumors: New patient‐derived orthotopic xenografts, cell lines and tumor entities	41
NKG2A and circulating extracellular vesicles are key regulators of natural killer cell activity in prostate cancer after prostatectomy	37
Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐ CD 73/anti‐	35
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for	34
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer	34
Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity	34
Interaction between membranous EBP50 and myosin 9 as a favorable prognostic factor in ovarian clear cell carcinoma	31
Vandetanib drives growth arrest and promotes sensitivity to imatinib in chronic myeloid leukemia by targeting ephrin type‐B receptor 4	30

Assessment of tumor burden and response to therapy in patients with colorectal cancer using a quantitative ctDNA test for methylated BCAT1/IKZF1	30
Ovarian cancer relies on the PDGFRβ –fibronectin axis for tumorsphere formation and metastatic spread	30
Prognostic and predictive impact of gene expression in node‐positive early breast cancer patients receiving dose‐dense versus standard‐dose adjuvant chemotherapy	29
Whole‐genome sequencing of cell‐free DNA reveals DNA of tumor origin in plasma from patients with	29
Prospective clinical sequencing of 1016 Chinese prostate cancer patients: uncovering genomic characterization and race disparity	29
Lysosome‐dependent FOXA1 ubiquitination contributes to luminal lineage of advanced prostate cancer	29
Proteomics on malignant pleural effusions reveals ERα loss in metastatic breast cancer associates with SGK1	29
Erratum to: Circulating tumor DNA as a biomarker for monitoring early treatment responses of patients with advanced lung adenocarcinoma receiving immune checkpoint inhibitors	29
Development of an optimized, non‐stem cell line for intranasal delivery of therapeutic cargo to the central nervous system	28
Exosomes secreted by ST3GAL5high cancer cells promote peritoneal dissemination by establishing a premetastatic microenvironment	28
Targeted therapy of advanced parathyroid carcinoma guided by genomic and transcriptomic profiling	28
Nanosecond pulsed electric field ablation‐induced modulation of sphingolipid metabolism is associated with Ly6c2 + mononuc	28
The multispecies microbial cluster of Fusobacterium , Parvimonas , Bacteroides	27
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RETRACTION: Long Noncoding RNA ZNF667‐AS1 Reduces Tumor Invasion and Metastasis in Cervical Cancer by Counteracting Microrna‐93‐3p‐Dependent PEG3 Downregulation	27
Hijacking the BAF complex: the mechanistic interplay of ARID1A and EWS::FLI1 in Ewing sarcoma	26
A single gene mutation predicts response to immune checkpoint blockade in ovarian clear cell carcinoma	26
Correction to: Clinical and biological relevance of the transcriptomic‐based prostate cancer metastasis subtypes MetA‐C	26
Cancer cachexia: biomarkers and the influence of age	25
Disruption of tp53 leads to cutaneous nevus and melanoma formation in Xenopus tropicalis	25
Stroma gene signature predicts responsiveness to chemotherapy in pancreatic ductal adenocarcinoma patient‐derived xenograft models	25
Academia and society should join forces to make anti‐cancer treatments more affordable	25
Glioblastoma and cerebral organoids: development and analysis of an in vitro model for glioblastoma migration	25
ANGPTL2 ‐mediated epigenetic repression of MHC‐I in tumor cells accelerates tumor immune evasion	24
Trapping all ERBB ligands decreases pancreatic lesions in a murine model of pancreatic ductal adenocarcinoma	24
Proteome‐based molecular subtyping and therapeutic target prediction in gastric cancer	24
T2R bitter taste receptors regulate apoptosis and may be associated with survival in head and neck squamous cell carcinoma	24
RNA polymerase I inhibition induces terminal differentiation, growth arrest, and vulnerability to senolytics in colorectal cancer cells	24
Exploring the significance of PAK1 through chromosome conformation signatures in ibrutinib‐resistant chronic lymphocytic leukaemia	23
Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic–mitochondrial tricarboxylic acid cycle that can be targeted for therapeutic purposes in prostate cancer	23
Germline variants in CDKN2A wild‐type melanoma prone families	23
Integration of single‐cell and bulk RNA ‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer	23
Combining variant detection and fragment length analysis improves detection of minimal residual disease in postsurgery circulating tumour DNA of stag	22
New retinoblastoma (RB) drug delivery approaches: anti‐tumor effect of atrial natriuretic peptide (ANP)‐conjugated hyaluronic‐acid‐coated gold nanoparticles for intraocular treat	21
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Replenishing co‐downregulated miR‐100‐5p and miR‐125b‐5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption	20
Retraction statement: Consistency analysis of microRNA‐arm expression reveals microRNA‐369‐5p/3p as tumor suppressors in gastric cancer	20
Issue Information	20
Correction to “The polyamine transporter ATP13A3 mediates difluoromethylornithine‐induced polyamine uptake in neuroblastoma”	20
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Serine protease inhibitors decrease metastasis in prostate, breast, and ovarian cancers	19
A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications	19
DRD1 suppresses cell proliferation and reduces EGFR activation and PD‐L1	19
Combined blockade of GPX4 and activated EGFR/HER3 bypass pathways inhibits the development of ALK‐inhibitor‐induced tolerant persister cells in ALK<	19
Analysis of genomic and immune intratumor heterogeneity in linitis plastica via multiregional exome and T‐cell receptor sequencing	19
LncRNA miR205HG hinders HNRNPA0 translation: anti‐oncogenic effects in esophageal carcinoma	19
Tetraploidy‐linked sensitization to CENP‐E inhibition in human cells	18
NNK from tobacco smoking enhances pancreatic cancer cell stemness and chemoresistance by creating a β2AR‐Akt feedback loop that activates autophagy	18
Correction to “The prostate metastasis suppressor gene NDRG1 differentially regulates cell motility and invasion”	18
Rational combination of SHP2 and mTOR inhibition for the treatment of hepatocellular carcinoma	18

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Sustained cancer‐relevant alternative RNA splicing events driven by PRMT5 in high‐risk neuroblasto	18
The LIN28B –let‐7– PBK pathway is essential for group 3 medulloblastoma tumor growth and survival	18
SETD2 loss in renal epithelial cells drives epithelial‐to‐mesenchymal transition in a TGF‐β‐independent manner	18
Post‐prostatic‐massage urine exosomes of men with chronic prostatitis/chronic pelvic pain syndrome carry prostate‐cancer‐typical micro RNA s and acti	17
Mcl‐1 and Bcl‐xL levels predict responsiveness to dual MEK/Bcl‐2 inhibition in B‐cell malignancies	17
Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic	17
Rodent models of tumours of the central nervous system	17
Lipidomic profiling of exosomes from colorectal cancer cells and patients reveals potential biomarkers	17
Intein‐based modular chimeric antigen receptor platform for specific CD19 / CD20 co‐targeting	16
FGF7–FGFR2 autocrine signaling increases growth and chemoresistance of fusion‐positive rhabdomyosarcomas	16
Abstracts	16
KRAS inhibitors: going noncovalent	16
Cancer as an infective disease: the role of EVs in tumorigenesis	16
Cancer outcome research – a European challenge Part II: Opportunities and priorities	16
PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism	16
DNA repair as a shared hallmark in cancer and ageing	16
Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel	16
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential	16
Long noncoding RNAs with peptide‐encoding potential identified in esophageal squamous cell carcinoma: KDM4A‐AS1‐encoded peptide weakens cancer cell viability and migratory capacity	16
Functional loss of ERBB receptor feedback inhibitor 1 ( MIG6 ) promotes glioblastoma tumorigenesis	16
Preclinical efficacy of carfilzomib in BRAF ‐mutant colorectal cancer models	16
Prognostic association of immunoproteasome expression in solid tumours is governed by the immediate immune environment	16
RNA cytosine methyltransferase NSUN5 promotes protein synthesis and tumorigenic phenotypes in glioblastoma	16
Targeting protein folding in N‐Myc‐driven medulloblastoma	16
MMP14 expression and collagen remodelling support uterine leiomyosarcoma aggressiveness	16
Precision medicine‐based therapies in advanced colorectal cancer: The University of California San Diego Molecular Tumor Board experience	15
Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients	15
CHML is an NRF2 target gene that regulates mTOR function	15
Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models	15
Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7 ‐mutated	15
Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of	15
Predicting dynamic response to neoadjuvant chemotherapy in breast cancer: a novel metabolomics approach	15
Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer	15
Assay‐agnostic spatial profiling detects tumor microenvironment signatures: new diagnostic insights for triple‐negative breast cancer	15
Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation	15
A rapid, multiplex digital PCR assay to detect gene variants and fusions in non‐small cell lung cancer	14
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In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma	14
Assembly of glioblastoma tumoroids and cerebral organoids: a 3Din vitro model for tumor cell invasion	14
Retraction Statement: Circ‐TCF4.85 silencing inhibits cancer progression through microRNA‐486‐5p‐targeted inhibition of ABCF2 in hepatocellular carcinoma	14
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance	14
Lipid metabolism in B cell biology	14
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Expression of circular RNAs in myelodysplastic neoplasms and their association with mutations in the splicing factor gene SF3B1	14
Microglia and macrophages in glioblastoma: landscapes and treatment directions	14
Targeting cellular senescence to combat cancer and ageing	14
Liver X receptors induce antiproliferative effects in basal‐like breast cancer	13
cAMP ‐phosphodiesterase 4D7 ( PDE4D7 ) forms a	13
Atezolizumab and stereotactic body radiotherapy in patients with advanced non‐small cell lung cancer: safety, clinical activity and ctDNA responses—t	13
PP2A ‐based triple‐strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells	13
Simultaneous detection of eight cancer types using a multiplex droplet digital PCR assay	13
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs	13
PELP1 inhibition by SMIP34 reduces endometrial cancer progression via attenuation of ribosomal biogenesis	13
Liquid biopsy: circulating tumor DNA monitors neoadjuvant chemotherapy response and prognosis in stage II/III gastric cancer	13
Targeting senescence as an anticancer therapy	12
The correlation between clinical outcomes and genomic analysis with high risk factors for the progression of osteosarcoma	12
Pharmacological degradation of ATR induces antiproliferative DNA replication stress in leukemic ce	12
Expression of Concern: T‐LAK cell‐originated protein kinase (TOPK): an emerging prognostic biomarker and therapeutic target in osteosarcoma	12
Plasma extrachromosomal circular DNA as a biomarker in EGFR ‐targeted therapy of non‐small cell lu	12
SOS2 modulates the threshold of EGFR signaling to regulate osimertinib efficacy and resistance in lung adenocarcinoma	12
ATF4 ‐mediated stress response as a therapeutic vulnerability in chordoma	12
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Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia	12
Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA	12
Protein palmitoylation in cancer: molecular functions and therapeutic potential	12
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma	12
Immune escape of colorectal tumours via local LRH‐1/Cyp11b1‐mediated synthesis of immunosuppressive glucocorticoids	11
ARID1A ‐deficient cells require HDAC6 for progression of endometrial carcinoma	11
SKA1 promotes oncogenic properties in oral dysplasia and oral squamous cell carcinoma, and augments resistance to radi	11
Thioredoxin‐interacting protein ( TXNIP ) is a substrate of the NEDD4 ‐like	11
Copy number variations contribute to malignant tumor development in children with serious birth defects	11
Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional valida	11
From bedside to portable and wearable: development of a conformable ultrasound patch for deep breast tissue imaging	11
SMG1 , a nonsense‐mediated mRNA decay ( NMD ) regulator, as a candi	11
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway	11

Enhanced reversal of ABCG2‐mediated drug resistance by replacing a phenyl ring in baicalein with a meta ‐carborane	11
Postbiotics of Lacticaseibacillus paracasei CECT 9610 and Lactiplantibacillus plantarum	11
Metabolism in the tumor cell and beyond	11
Current status of precision oncology in adult glioblastoma	11
The invariant chain CD74 protein is a cell surface binding partner of TIMP‐1 in breast cancer cells	11
Loss of Lkb1 cooperates with Braf V600E	11
Comparative membrane lipidomics of hepatocellular carcinoma cells reveals diacylglycerol and ceramide as key regulators of Wnt/β‐catenin signaling and tumor growth	11
The polyamine transporter ATP13A3 mediates difluoromethylornithine‐induced polyamine uptake in neuroblastoma	11
Conditional ERK3 overexpression cooperates with PTEN deletion to promote lung adenocarcinoma formation in	11
Immune evasion: An imperative and consequence of MYC deregulation	11
GALNT2 promotes invasiveness of colorectal cancer cells partly through AXL	10
CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma	10
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miR‐200a/b/‐429 downregulation is a candidate biomarker of tumor radioresistance and independent of hypoxia in locally advanced cervical cancer	10
Bovine meat and milk factor protein expression in tumor‐free mucosa of colorectal cancer patients coincides with macrophages and might interfere with patient survival	10
Low levels of WRAP53 predict decreased efficacy of radiotherapy and are prognostic for local recurrence and death from breast cancer: a long‐term fol	10
Fragment‐based drug discovery—the importance of high‐quality molecule libraries	10
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The roles and applications of extracellular vesicles in cancer	10
Integrated analysis of racial disparities in genomic architecture identifies a trans‐ancestry prognostic subtype in bladder cancer	10
Beyond cytotoxic T cells: reprogrammed regulatory T cells help facilitate response to dual checkpoint blockade	10
Issue Information	10
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients	10
Advanced strategies in improving the immunotherapeutic effect of CAR‐T cell therapy	10
Transcriptomic pan‐cancer analysis using rank‐based Bayesian inference	10
Nicotinamide (niacin) supplement increases lipid metabolism and ROS‐induced energy disruption in triple‐negative breast cancer: potential for drug repositioning as an anti‐tumor agent	10
MASH as an emerging cause of hepatocellular carcinoma: current knowledge and future perspectives	9
TREX1 , a predator for treating MSI ‐H tumors?	9
Oncogenic composite mutations can be predicted by co‐mutations and their chromosomal location	9
Transcription factor 4 is a key mediator of oncogenesis in neuroblastoma by promoting MYC activity	9
Identification and targeting of a HES1‐YAP1‐CDKN1C functional interaction in fusion‐negative rhabdomyosarcoma	9
Unraveling epigenetic heterogeneity across gastrointestinal adenocarcinomas through a standardized analytical framework	9
Interferon regulatory factor 4 modulates epigenetic silencing and cancer‐critical pathways in melanoma cells	9
Evaluation of circulating tumor DNA as a prognostic and predictive biomarker in BRAF V600E	9
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer	9
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Pre‐ and post‐treatment blood‐based genomic landscape of patients with ROS1 or NTRK fusion‐positive solid tumours treated with entrectinib	9
Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β i	9
Risk stratification of indeterminate thyroid nodules by novel multigene testing: a study of Asians with a high risk of malignancy	9
ERBB2 mutations define a subgroup of endometrial carcinomas associated with high tumor mutational burden and the microsatellite instability‐high ( M	9
Resistance prediction in high‐grade serous ovarian carcinoma with neoadjuvant chemotherapy using data‐independent acquisition proteomics and an ovary‐specific spectral library	9
Levels of circulating tumor DNA correlate with tumor volume in gastro‐intestinal stromal tumors: an exploratory long‐term follow‐up study	9
LIM domain‐containing protein Ajuba inhibits chemotherapy‐induced apoptosis by negatively regulating p53 stability in colorectal cancer cells	9
Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with	9
The prevalence and prognosis of next‐generation therapeutic targets in metastatic castration‐resistant prostate cancer	9
Deciphering metabolic crosstalk in context: lessons from inflammatory diseases	9
Viral mimicry evasion: a new role for oncogenic KRAS mutations	9
Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities	9
Investigation of somatic mutation profiles and tumor evolution of primary oropharyngeal cancer and sequential lymph node metastases using multiregional whole‐exome sequencing	9
Ribosome biogenesis‐based predictive biomarkers in endocrine therapy (Anastrozole) combined with mTOR inhibitor (Vistusertib) in endometrial cancer:	9
Identifying the personalized driver gene sets maximally contributing to abnormality of transcriptome phenotype in glioblastoma multiforme individuals	9
Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early no	9
Inhibition of CDCP1 by 8‐isopentenylnaringenin synergizes with EGFR inhibitors in lung cancer trea	9
Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen ther	9
Ex vivo mapping of enhancer networks that define the transcriptional program driving melanoma metastasis	9
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?	9
The critical role of DNA damage‐inducible transcript 4 ( DDIT4 ) in stemness character of leukemia	9
The sculpting of somatic mutational landscapes by evolutionary forces and their impacts on aging‐related disease	8
Novel insights into molecular patterns of ROS1 fusions in a large Chinese NSCLC cohort: a multicenter study	8
PPM1D activity promotes the replication stress caused by cyclin E1 overexpression	8
PP2A methylesterase PME ‐1 suppresses anoikis and is associated with therapy relapse of	8
Liquid profiling of circulating tumor DNA in colorectal cancer: steps needed to achieve its full clinical value as standard care	8
High CD34 surface expression in BCP‐ALL predicts poor induction therapy response and is associated with altered expression of genes related to cell migration and adhesion	8
Enhancing therapeutic efficacy in triple‐negative breast cancer and melanoma: synergistic effects of modulated electro‐hyperthermia (mEHT) with NSAIDs especially COX‐2 inhibition in	8
Recurrence/prognosis estimation using a molecularly positive surgical margin‐based model calls for alternative curative strategies in pIIIA/N2 NSCLC	8
Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing	8
Chimeric diphtheria toxin– CCL8 cytotoxic peptide for breast cancer management	8
Inhibition of acyl‐ CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction	8
Predictors of response and rational combinations for the novel MCL ‐1 inhibitor MIK665 in acute my	8
Screening of an annexin‐A2 ‐targeted heptapeptide for pancreatic adenocarcinoma localization	8
Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product	8
Proximity proteomics reveals role of Abelson interactor 1 in the regulation of TAK1 / RIPK1 signal	8
Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and	8
Transcriptional analysis of landmark molecular pathways in lung adenocarcinoma results in a clinically relevant classification with potential therapeutic implications	8
Exportin 1‐mediated nuclear/cytoplasmic trafficking controls drug sensitivity of classical Hodgkin's lymphoma	8
Expression pattern of secretory‐cell‐related transcriptional signatures in colon adenocarcinomas defines tumor microenvironment characteristics and correlates with clinical outcomes	8
In the spotlight: Julio Celis, the Founding Editor of Molecular Oncology	8
Plasma membrane SK2 channel activity regulates migration and chemosensitivity of high‐grade serous ovarian cancer cells	8
Metabolism and signaling crosstalk in glioblastoma progression and therapy resistance	8
CDK 11 inhibition induces cytoplasmic p21 WAF 1	8
Ebselen oxide and derivatives are new allosteric HER2 inhibitors for HER2 ‐positive cancers	8
Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker	8
Overexpression of the pro‐protein convertase furin predicts prognosis and promotes papillary thyroid carcinoma progression and metastasis through RAF	8
ITIH5 as a multifaceted player in pancreatic cancer suppression, impairing tyrosine kinase signaling, cell adhesion and migration	8
Cell‐free chromatin immunoprecipitation can determine tumor gene expression in lung cancer patients	8
RNA m6Amethylation in cancer	8
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