Molecular Oncology

Article	Citations
Issue Information	155
	140
Evaluation of two new highly multiplexed PCR assays as an alternative to next‐generation sequencing for IDH1/2 mutation detection	117
Lysosome‐dependent FOXA1 ubiquitination contributes to luminal lineage of advanced prostate cancer	94
Ovarian cancer relies on the PDGFRβ –fibronectin axis for tumorsphere formation and metastatic spread	89
Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity	83
Whole‐genome sequencing of cell‐free DNA reveals DNA of tumor origin in plasma from patients with	81
PoDCall: a robust tool for automated droplet classification in DNA‐methylation droplet digital PCR	79
	75
Corrigendum to: Small proline‐rich repeat protein 3 enhances the sensitivity of esophageal cancer cells in response to DNA damage‐induced apoptosis	69
Correction to “Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition”	59
NKG2A and circulating extracellular vesicles are key regulators of natural killer cell activity in prostate cancer after prostatectomy	58
Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo	49
Gene signature predicting recurrence in oral squamous cell carcinoma is characterized by increased oxidative phosphorylation	42
The multispecies microbial cluster of Fusobacterium , Parvimonas , Bacteroides	41
Targeted therapy of advanced parathyroid carcinoma guided by genomic and transcriptomic profiling	38
An arms‐race against resistance: leukemic stem cells and lineage plasticity	38
Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐ CD 73/anti‐	37
Nanosecond pulsed electric field ablation‐induced modulation of sphingolipid metabolism is associated with Ly6c2 + mononuc	35
Unraveling LINE ‐1 retrotransposition in head and neck squamous cell carcinoma	33
Precision Cancer Medicine 2.0—Oncology in the postgenomic era	32
Correction to “SPT6 recruits SND1 to co‐activate human telomerase reverse transcriptase to promote colon cancer progression”	32
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for	32
PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer	32
Exosomes secreted by ST3GAL5high cancer cells promote peritoneal dissemination by establishing a premetastatic microenvironment	31

Interaction between membranous EBP50 and myosin 9 as a favorable prognostic factor in ovarian clear cell carcinoma	31
Vandetanib drives growth arrest and promotes sensitivity to imatinib in chronic myeloid leukemia by targeting ephrin type‐B receptor 4	30
Development of an optimized, non‐stem cell line for intranasal delivery of therapeutic cargo to the central nervous system	30
Expanding a precision medicine platform for malignant peripheral nerve sheath tumors: New patient‐derived orthotopic xenografts, cell lines and tumor entities	29
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer	29
Proteomics on malignant pleural effusions reveals ERα loss in metastatic breast cancer associates with SGK1	28
Prognostic and predictive impact of gene expression in node‐positive early breast cancer patients receiving dose‐dense versus standard‐dose adjuvant chemotherapy	28
The selenoenzyme type I iodothyronine deiodinase: a new tumor suppressor in ovarian cancer	28
Issue Information	27
Prospective clinical sequencing of 1016 Chinese prostate cancer patients: uncovering genomic characterization and race disparity	25
ANGPTL2 ‐mediated epigenetic repression of MHC‐I in tumor cells accelerates tumor immune evasion	25
Cancer cachexia: biomarkers and the influence of age	25
Proteome‐based molecular subtyping and therapeutic target prediction in gastric cancer	25
Glioblastoma and cerebral organoids: development and analysis of an in vitro model for glioblastoma migration	24
Combining variant detection and fragment length analysis improves detection of minimal residual disease in postsurgery circulating tumour DNA of stag	24
Germline variants in CDKN2A wild‐type melanoma prone families	24
Disruption of tp53 leads to cutaneous nevus and melanoma formation in Xenopus tropicalis	24
Integration of single‐cell and bulk RNA ‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer	23
RNA polymerase I inhibition induces terminal differentiation, growth arrest, and vulnerability to senolytics in colorectal cancer cells	23
Trapping all ERBB ligands decreases pancreatic lesions in a murine model of pancreatic ductal adenocarcinoma	23
Hijacking the BAF complex: the mechanistic interplay of ARID1A and EWS::FLI1 in Ewing sarcoma	23
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer	22
A single gene mutation predicts response to immune checkpoint blockade in ovarian clear cell carcinoma	22
Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic–mitochondrial tricarboxylic acid cycle that can be targeted for therapeutic purposes in prostate cancer	22
Correction to: Clinical and biological relevance of the transcriptomic‐based prostate cancer metastasis subtypes MetA‐C	21
Academia and society should join forces to make anti‐cancer treatments more affordable	21
RETRACTION : Long Noncoding RNA ZNF667‐AS1 Reduces Tumor Invasion and Metastasis in Cervical Cancer by Counteracting Microrna‐93‐3p‐Dependent PEG3 Downregulation	21
Stroma gene signature predicts responsiveness to chemotherapy in pancreatic ductal adenocarcinoma patient‐derived xenograft models	21
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology	20
Issue Information	20
Exploring the significance of PAK1 through chromosome conformation signatures in ibrutinib‐resistant chronic lymphocytic leukaemia	20
New retinoblastoma (RB) drug delivery approaches: anti‐tumor effect of atrial natriuretic peptide (ANP)‐conjugated hyaluronic‐acid‐coated gold nanoparticles for intraocular treat	20
DNA methylation and expression of MAPRE3 affect overall survival of	20
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Serine protease inhibitors decrease metastasis in prostate, breast, and ovarian cancers	19
Retraction statement: Consistency analysis of microRNA ‐arm expression reveals microRNA ‐369‐5p/3p	19
Issue Information	19
NNK from tobacco smoking enhances pancreatic cancer cell stemness and chemoresistance by creating a β2AR‐Akt feedback loop that activates autophagy	19
Tetraploidy‐linked sensitization to CENP‐E inhibition in human cells	19
Correction to “The polyamine transporter ATP13A3 mediates difluoromethylornithine‐induced polyamine uptake in neuroblastoma”	18
Replenishing co‐downregulated miR‐100‐5p and miR‐125b‐5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption	18
Combined blockade of GPX4 and activated EGFR/HER3 bypass pathways inhibits the development of ALK‐inhibitor‐induced tolerant persister cells in ALK<	18
Rational combination of SHP2 and mTOR inhibition for the treatment of hepatocellular carcinoma	18
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Analysis of genomic and immune intratumor heterogeneity in linitis plastica via multiregional exome and T‐cell receptor sequencing	18
Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples	18
E2A selectively regulates TGF‐β–induced apoptosis in KRAS ‐mutant non‐small cell lung cancer	18
DRD1 suppresses cell proliferation and reduces EGFR activation and PD‐L1	17
European Code Against Cancer, 5th edition – cancer‐causing infections and related interventions	17
Sustained cancer‐relevant alternative RNA splicing events driven by PRMT5 in high‐risk neuroblasto	17

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer	17
The LIN28B –let‐7– PBK pathway is essential for group 3 medulloblastoma tumor growth and survival	17
Targeting protein folding in N‐Myc‐driven medulloblastoma	16
SETD2 loss in renal epithelial cells drives epithelial‐to‐mesenchymal transition in a TGF‐β‐independent manner	16
A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications	16
Cancer as an infective disease: the role of EVs in tumorigenesis	16
Issue Information	16
Correction to “The prostate metastasis suppressor gene NDRG 1 differentially regulates cell motility and invasion”	16
MMP14 expression and collagen remodelling support uterine leiomyosarcoma aggressiveness	15
Intein‐based modular chimeric antigen receptor platform for specific CD19 / CD20 co‐targeting	15
Issue Information	15
Prognostic association of immunoproteasome expression in solid tumours is governed by the immediate immune environment	15
Long noncoding RNAs with peptide‐encoding potential identified in esophageal squamous cell carcinoma: KDM4A‐AS1‐encoded peptide weakens cancer cell viability and migratory capacity	15
Rodent models of tumours of the central nervous system	15
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity	15
Preclinical efficacy of carfilzomib in BRAF ‐mutant colorectal cancer models	14
Molecular cancer prevention: Intercepting disease	14
DNA repair as a shared hallmark in cancer and ageing	14
Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer	14
Post‐prostatic‐massage urine exosomes of men with chronic prostatitis/chronic pelvic pain syndrome carry prostate‐cancer‐typical micro RNA s and acti	14
PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism	14
Functional loss of ERBB receptor feedback inhibitor 1 ( MIG6 ) promotes glioblastoma tumorigenesis	14
RNA cytosine methyltransferase NSUN5 promotes protein synthesis and tumorigenic phenotypes in glioblastoma	14
Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic	14
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential	14
Lipidomic profiling of exosomes from colorectal cancer cells and patients reveals potential biomarkers	14
Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients	14
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KRAS inhibitors: going noncovalent	13
Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models	13
Abstracts	13
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers	13
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma	13
Issue Information	13
Potential therapeutic targeting of BK Ca channels in glioblastoma treatment	13
Assembly of glioblastoma tumoroids and cerebral organoids: a 3Din vitro model for tumor cell invasion	13
Assay‐agnostic spatial profiling detects tumor microenvironment signatures: new diagnostic insights for triple‐negative breast cancer	13
Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel	13
Issue Information	13
Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation	13
European Code Against Cancer, 5th edition – tobacco and nicotine containing products, second‐hand smoke, alcohol and cancer	13
A rapid, multiplex digital PCR assay to detect gene variants and fusions in non‐small cell lung cancer	13
Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of	13
Retraction Statement: Circ‐TCF4 .85 silencing inhibits cancer progression through microRNA ‐486‐5p	13
Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7 ‐mutated	13
Simultaneous detection of eight cancer types using a multiplex droplet digital PCR assay	12
Targeting cellular senescence to combat cancer and ageing	12
PELP1 inhibition by SMIP34 reduces endometrial cancer progression via attenuation of ribosomal biogenesis	12
PP2A ‐based triple‐strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells	12
In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma	12
cAMP ‐phosphodiesterase 4D7 ( PDE4D7 ) forms a	12
The correlation between clinical outcomes and genomic analysis with high risk factors for the progression of osteosarcoma	12
SOS2 modulates the threshold of EGFR signaling to regulate osimertinib efficacy and resistance in lung adenocarcinoma	12
Expression of circular RNAs in myelodysplastic neoplasms and their association with mutations in the splicing factor gene SF3B1	12
Liquid biopsy: circulating tumor DNA monitors neoadjuvant chemotherapy response and prognosis in stage II/III gastric cancer	12
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs	12
Liver X receptors induce antiproliferative effects in basal‐like breast cancer	12
LDAcoop : Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro	12
Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia	11
CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cance	11
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance	11
Targeting senescence as an anticancer therapy	11
Issue Information	11
Metabolism in the tumor cell and beyond	11
Protein palmitoylation in cancer: molecular functions and therapeutic potential	11
Lipid metabolism in B cell biology	11
ATF4 ‐mediated stress response as a therapeutic vulnerability in chordoma	11
Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA	11
Atezolizumab and stereotactic body radiotherapy in patients with advanced non‐small cell lung cancer: safety, clinical activity and ctDNA responses—t	11
The invariant chain CD74 protein is a cell surface binding partner of TIMP‐1 in breast cancer cells	11
Immune evasion: An imperative and consequence of MYC deregulation	11
Microglia and macrophages in glioblastoma: landscapes and treatment directions	11
Pharmacological degradation of ATR induces antiproliferative DNA replication stress in leukemic ce	11
Plasma extrachromosomal circular DNA as a biomarker in EGFR ‐targeted therapy of non‐small cell lu	11
Issue Information	11
From bedside to portable and wearable: development of a conformable ultrasound patch for deep breast tissue imaging	11
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients	10
The polyamine transporter ATP13A3 mediates difluoromethylornithine‐induced polyamine uptake in neuroblastoma	10
Loss of Lkb1 cooperates with Braf V600E	10
COMP – PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells	10

Fragment‐based drug discovery—the importance of high‐quality molecule libraries	10
Copy number variations contribute to malignant tumor development in children with serious birth defects	10
Comparative membrane lipidomics of hepatocellular carcinoma cells reveals diacylglycerol and ceramide as key regulators of Wnt/β‐catenin signaling and tumor growth	10
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway	10
SKA1 promotes oncogenic properties in oral dysplasia and oral squamous cell carcinoma, and augments resistance to radi	10
SMG1 , a nonsense‐mediated mRNA decay ( NMD ) regulator, as a candi	10
Immune escape of colorectal tumours via local LRH‐1/Cyp11b1‐mediated synthesis of immunosuppressive glucocorticoids	10
Thioredoxin‐interacting protein ( TXNIP ) is a substrate of the NEDD4 ‐like	10
CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma	10
Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional valida	10
Expression of Concern: T‐ LAK cell‐originated protein kinase ( TOPK ): an emerging prognostic biom	10
Postbiotics of Lacticaseibacillus paracasei CECT 9610 and Lactiplantibacillus plantarum	10
GALNT2 promotes invasiveness of colorectal cancer cells partly through AXL	10
Current status of precision oncology in adult glioblastoma	10
Enhanced reversal of ABCG2‐mediated drug resistance by replacing a phenyl ring in baicalein with a meta ‐carborane	10
Resistance prediction in high‐grade serous ovarian carcinoma with neoadjuvant chemotherapy using data‐independent acquisition proteomics and an ovary‐specific spectral library	9
Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen ther	9
Unraveling epigenetic heterogeneity across gastrointestinal adenocarcinomas through a standardized analytical framework	9
Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma	9
Levels of circulating tumor DNA correlate with tumor volume in gastro‐intestinal stromal tumors: an exploratory long‐term follow‐up study	9
Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog	9
Bovine meat and milk factor protein expression in tumor‐free mucosa of colorectal cancer patients coincides with macrophages and might interfere with patient survival	9
The critical role of DNA damage‐inducible transcript 4 ( DDIT4 ) in stemness character of leukemia	9
Identifying the personalized driver gene sets maximally contributing to abnormality of transcriptome phenotype in glioblastoma multiforme individuals	9
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Low levels of WRAP53 predict decreased efficacy of radiotherapy and are prognostic for local recurrence and death from breast cancer: a long‐term fol	9
TREX1 , a predator for treating MSI ‐H tumors?	9
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The prevalence and prognosis of next‐generation therapeutic targets in metastatic castration‐resistant prostate cancer	9
Oncogenic composite mutations can be predicted by co‐mutations and their chromosomal location	9
The roles and applications of extracellular vesicles in cancer	9
Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with	9
Advanced strategies in improving the immunotherapeutic effect of CAR‐T cell therapy	9
Transcription factor 4 is a key mediator of oncogenesis in neuroblastoma by promoting MYC activity	9
Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ ALL pediatric patients with high	9
Issue Information	9
TRAIL ‐ PEG ‐Apt‐ PLGA nanosystem as an aptamer‐targeted drug deliv	9
Beyond cytotoxic T cells: reprogrammed regulatory T cells help facilitate response to dual checkpoint blockade	9
ERBB2 mutations define a subgroup of endometrial carcinomas associated with high tumor mutational burden and the microsatellite instability‐high ( M	9
Interferon regulatory factor 4 modulates epigenetic silencing and cancer‐critical pathways in melanoma cells	9
MASH as an emerging cause of hepatocellular carcinoma: current knowledge and future perspectives	9
Ribosome biogenesis‐based predictive biomarkers in endocrine therapy (Anastrozole) combined with mTOR inhibitor (Vistusertib) in endometrial cancer:	9
Integrated analysis of racial disparities in genomic architecture identifies a trans‐ancestry prognostic subtype in bladder cancer	9
LIM domain‐containing protein Ajuba inhibits chemotherapy‐induced apoptosis by negatively regulating p53 stability in colorectal cancer cells	9
Evaluation of circulating tumor DNA as a prognostic and predictive biomarker in BRAF V600E	9
Investigation of somatic mutation profiles and tumor evolution of primary oropharyngeal cancer and sequential lymph node metastases using multiregional whole‐exome sequencing	9
Inhibition of CDCP1 by 8‐isopentenylnaringenin synergizes with EGFR inhibitors in lung cancer trea	9
Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities	9
Identification and targeting of a HES1‐YAP1‐CDKN1C functional interaction in fusion‐negative rhabdomyosarcoma	9
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Transcriptomic pan‐cancer analysis using rank‐based Bayesian inference	9
Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early no	9
Engineered extracellular vesicles enriched with the miR ‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer	9
Overexpression of the pro‐protein convertase furin predicts prognosis and promotes papillary thyroid carcinoma progression and metastasis through RAF	8
CDK 11 inhibition induces cytoplasmic p21 WAF 1	8
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?	8
Proximity proteomics reveals role of Abelson interactor 1 in the regulation of TAK1 / RIPK1 signal	8
Targeting p38α in cancer: challenges, opportunities, and emerging strategies	8
Ex vivo mapping of enhancer networks that define the transcriptional program driving melanoma metastasis	8
PPM1D activity promotes the replication stress caused by cyclin E1 overexpression	8
Predictors of response and rational combinations for the novel MCL ‐1 inhibitor MIK665 in acute my	8
The sculpting of somatic mutational landscapes by evolutionary forces and their impacts on aging‐related disease	8
Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and	8
Endometrioid ovarian carcinoma landscape: pathological and molecular characterization	8
Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab	8
Expression pattern of secretory‐cell‐related transcriptional signatures in colon adenocarcinomas defines tumor microenvironment characteristics and correlates with clinical outcomes	8
Deciphering metabolic crosstalk in context: lessons from inflammatory diseases	8
Inhibition of acyl‐ CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction	8
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer	8
PP2A methylesterase PME ‐1 suppresses anoikis and is associated with therapy relapse of	8
Exportin 1‐mediated nuclear/cytoplasmic trafficking controls drug sensitivity of classical Hodgkin's lymphoma	8
Enhancing therapeutic efficacy in triple‐negative breast cancer and melanoma: synergistic effects of modulated electro‐hyperthermia (mEHT) with NSAIDs especially COX‐2 inhibition in	8
Screening of an annexin‐A2 ‐targeted heptapeptide for pancreatic adenocarcinoma localization	8
Transcriptional analysis of landmark molecular pathways in lung adenocarcinoma results in a clinically relevant classification with potential therapeutic implications	8
ITIH5 as a multifaceted player in pancreatic cancer suppression, impairing tyrosine kinase signaling, cell adhesion and migration	8
Ebselen oxide and derivatives are new allosteric HER2 inhibitors for HER2 ‐positive cancers	8
A group of novel VEGF splice variants as alternative therapeutic targets in renal cell carcinoma	8
Issue Information	8
Recurrence/prognosis estimation using a molecularly positive surgical margin‐based model calls for alternative curative strategies in pIIIA/N2 NSCLC	8
Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker	8
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7 ‐	8
Chimeric diphtheria toxin– CCL8 cytotoxic peptide for breast cancer management	8
Viral mimicry evasion: a new role for oncogenic KRAS mutations	8
Metabolism and signaling crosstalk in glioblastoma progression and therapy resistance	8
Plasma membrane SK2 channel activity regulates migration and chemosensitivity of high‐grade serous ovarian cancer cells	8
Novel insights into molecular patterns of ROS1 fusions in a large Chinese NSCLC cohort: a multicenter study	8
Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients	8
Cell‐free chromatin immunoprecipitation can determine tumor gene expression in lung cancer patients	8
Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product	8
Immune‐related gene TM4SF18 could promote the metastasis of gastric cancer cells and predict the prognosis of gastric cancer patients	8
Optimising the European Code Against Cancer, 5th edition, to increase awareness of avoidable cancer risks in all socioeconomic groups	8
Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing	8