Molecular Oncology

Papers
(The median citation count of Molecular Oncology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)
ArticleCitations
Targeting immunogenic cell death in cancer373
Physical activity, obesity and sedentary behavior in cancer etiology: epidemiologic evidence and biologic mechanisms196
Elesclomol induces copper‐dependent ferroptosis in colorectal cancer cells via degradation of ATP7A110
LNCAROD is stabilized by m6A methylation and promotes cancer progression via forming a ternary complex with HSPA1A and YBX1 in head and neck squamous cell carcinoma110
DNA in extracellular vesicles: biological and clinical aspects95
Clinical utility of circulating tumor cells: an update94
The effect of surgical trauma on circulating free DNA levels in cancer patients—implications for studies of circulating tumor DNA86
Clearance of therapy‐induced senescent tumor cells by the senolytic ABT‐263 via interference with BCL‐XL–BAX interaction86
Radiotherapy–immunotherapy combinations – perspectives and challenges84
Exosome‐transmitted circ_MMP2 promotes hepatocellular carcinoma metastasis by upregulating MMP277
Prevention and treatment of radiotherapy‐induced side effects75
Cellular senescence in cancer: from mechanisms to detection73
Genetic alterations of malignant pleural mesothelioma: association with tumor heterogeneity and overall survival71
Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS–mitochondrial fission–mitophagy axis70
A robust multiplex immunofluorescence and digital pathology workflow for the characterisation of the tumour immune microenvironment65
Clinical significance of clonal hematopoiesis in the interpretation of blood liquid biopsy59
Identification and validation of a combined hypoxia and immune index for triple‐negative breast cancer58
Long noncoding RNA SLC2A1‐AS1 regulates aerobic glycolysis and progression in hepatocellular carcinoma via inhibiting the STAT3/FOXM1/GLUT1 pathway58
Image guidance in radiation therapy for better cure of cancer57
iRGD‐modified exosomes effectively deliver CPT1A siRNA to colon cancer cells, reversing oxaliplatin resistance by regulating fatty acid oxidation56
CircFNDC3B sequestrates miR‐937‐5p to derepress TIMP3 and inhibit colorectal cancer progression55
Global mapping of cancers: The Cancer Genome Atlas and beyond53
Autophagy, the innate immune response and cancer53
Technology‐driven research for radiotherapy innovation53
AAV‐mediated gene transfer of DNase I in the liver of mice with colorectal cancer reduces liver metastasis and restores local innate and adaptive immune response50
Particle therapy in Europe49
Overcoming the senescence‐associated secretory phenotype (SASP): a complex mechanism of resistance in the treatment of cancer49
LncRNA NKX2‐1‐AS1 promotes tumor progression and angiogenesis via upregulation of SERPINE1 expression and activation of the VEGFR‐2 signaling pathway in gastric cancer48
Distribution and prognostic significance of gluconeogenesis and glycolysis in lung cancer47
Provision and use of radiotherapy in Europe45
Dual inhibition of TGF‐β and PD‐L1: a novel approach to cancer treatment45
LncRNA AATBC regulates Pinin to promote metastasis in nasopharyngeal carcinoma44
METTL3/YTHDF2 m6A axis accelerates colorectal carcinogenesis through epigenetically suppressing YPEL544
Neuroendocrine subtypes of small cell lung cancer differ in terms of immune microenvironment and checkpoint molecule distribution44
Immune response drives outcomes in prostate cancer: implications for immunotherapy44
FOXD1‐AS1 regulates FOXD1 translation and promotes gastric cancer progression and chemoresistance by activating the PI3K/AKT/mTOR pathway43
Serum small extracellular vesicle‐derived LINC00853 as a novel diagnostic marker for early hepatocellular carcinoma43
Cancer diagnostics based on plasma protein biomarkers: hard times but great expectations43
Detection and relevance of epigenetic markers on ctDNA: recent advances and future outlook42
Doxorubicin‐induced senescence promotes stemness and tumorigenicity in EpCAM−/CD133− nonstem cell population in hepatocellular carcinoma cell line, HuH‐742
Enhancing cancer‐associated fibroblast fatty acid catabolism within a metabolically challenging tumor microenvironment drives colon cancer peritoneal metastasis41
Classification of diffuse lower‐grade glioma based on immunological profiling41
Early assessment of circulating tumor DNA after curative‐intent resection predicts tumor recurrence in early‐stage and locally advanced non‐small‐cell lung cancer39
Circulating platelets as liquid biopsy sources for cancer detection38
Variability of EGFR exon 20 insertions in 24 468 Chinese lung cancer patients and their divergent responses to EGFR inhibitors37
Tobacco control policies in the 21st century: achievements and open challenges37
Mast cell‐based molecular subtypes and signature associated with clinical outcome in early‐stage lung adenocarcinoma34
Linc‐ROR promotes the progression of breast cancer and decreases the sensitivity to rapamycin through miR‐194‐3p targeting MECP234
Retracted: Exosomal miR‐1255b‐5p targets human telomerase reverse transcriptase in colorectal cancer cells to suppress epithelial‐to‐mesenchymal transition33
Circulating tumor cell profiling for precision oncology33
TGFBI modulates tumour hypoxia and promotes breast cancer metastasis32
A novel prognostic mRNA/miRNA signature for esophageal cancer and its immune landscape in cancer progression32
Metabolomic profile of cancer stem cell‐derived exosomes from patients with malignant melanoma31
Circ_0008039 supports breast cancer cell proliferation, migration, invasion, and glycolysis by regulating the miR‐140‐3p/SKA2 axis31
Combination therapy with androgen receptor N‐terminal domain antagonist EPI‐7170 and enzalutamide yields synergistic activity in AR‐V7‐positive prostate cancer31
Cellular senescence and the tumour microenvironment31
Estrogen receptor α promotes lung cancer cell invasion via increase of and cross‐talk with infiltrated macrophages through the CCL2/CCR2/MMP9 and CXCL12/CXCR4 signaling pathways30
Deubiquitinase PSMD14 promotes ovarian cancer progression by decreasing enzymatic activity of PKM230
Role of ultraviolet mutational signature versus tumor mutation burden in predicting response to immunotherapy30
Fragment‐based drug discovery—the importance of high‐quality molecule libraries30
Human fibronectin extra domain B as a biomarker for targeted therapy in cancer29
Towards a cancer mission in Horizon Europe: recommendations29
Circulating exosomal miR‐363‐5p inhibits lymph node metastasis by downregulating PDGFB and serves as a potential noninvasive biomarker for breast cancer29
Analysis of DNA methylation patterns in the tumor immune microenvironment of metastatic melanoma29
Extracellular vesicles and oncogenic signaling29
The FABP12/PPARγ pathway promotes metastatic transformation by inducing epithelial‐to‐mesenchymal transition and lipid‐derived energy production in prostate cancer cells29
CircRNA EPHB4 modulates stem properties and proliferation of gliomas via sponging miR‐637 and up‐regulating SOX1028
Darolutamide antagonizes androgen signaling by blocking enhancer and super‐enhancer activation28
Periostin+cancer‐associated fibroblasts promote lymph node metastasis by impairing the lymphatic endothelial barriers in cervical squamous cell carcinoma28
LncRNA SOX2‐OT regulates AKT/ERK and SOX2/GLI‐1 expression, hinders therapy, and worsens clinical prognosis in malignant lung diseases28
FOXM1D potentiates PKM2‐mediated tumor glycolysis and angiogenesis28
Circular RNA profiling identifies circ102049 as a key regulator of colorectal liver metastasis28
Multifaceted activities of transcription factor EB in cancer onset and progression28
A novel cell‐free DNA methylation‐based model improves the early detection of colorectal cancer28
Comparison of variant allele frequency and number of mutant molecules as units of measurement for circulating tumor DNA27
SMARCA4 mutations in KRAS‐mutant lung adenocarcinoma: a multi‐cohort analysis27
Long noncoding RNA SNHG12 induces proliferation, migration, epithelial–mesenchymal transition, and stemness of esophageal squamous cell carcinoma cells via post‐transcriptional regulation of BMI1 and 27
Clinical implications of plasma circulating tumor DNA in gynecologic cancer patients27
Vitamin D supplementation to the older adult population in Germany has the cost‐saving potential of preventing almost 30 000 cancer deaths per year27
SENP3 loss promotes M2 macrophage polarization and breast cancer progression27
Long noncoding RNA DANCR confers cytarabine resistance in acute myeloid leukemia by activating autophagy via the miR‐874‐3P/ATG16L1 axis27
Resistance to DNA repair inhibitors in cancer27
Pericyte‐secreted IGF2 promotes breast cancer brain metastasis formation26
Histological and mutational profile of diffuse gastric cancer: current knowledge and future challenges26
Retracted: Long non‐coding RNA PGM5‐AS1 promotes epithelial‐mesenchymal transition, invasion and metastasis of osteosarcoma cells by impairing miR‐140‐5p‐mediated FBN1 inhibition26
The DNA methylation landscape of hematological malignancies: an update26
HPV‐related methylation‐based reclassification and risk stratification of cervical cancer26
LAMC1 upregulation via TGFβ induces inflammatory cancer‐associated fibroblasts in esophageal squamous cell carcinoma via NF‐κB–CXCL1–STAT326
EHMT1 knockdown induces apoptosis and cell cycle arrest in lung cancer cells by increasing CDKN1A expression26
Upregulation of cell surface GD3 ganglioside phenotype is associated with human melanoma brain metastasis26
Autophagy activation and SREBP‐1 induction contribute to fatty acid metabolic reprogramming by leptin in breast cancer cells25
Metabolic enzyme ACSL3 is a prognostic biomarker and correlates with anticancer effectiveness of statins in non‐small cell lung cancer25
Characterization of super‐enhancer‐associated functional lncRNAs acting as ceRNAs in ESCC25
Advances in optical gastrointestinal endoscopy: a technical review25
Targeting Hippo coactivator YAP1 through BET bromodomain inhibition in esophageal adenocarcinoma24
Targeted inhibition of STAT3 induces immunogenic cell death of hepatocellular carcinoma cells via glycolysis24
Long noncoding RNA LINC01578 drives colon cancer metastasis through a positive feedback loop with the NF‐κB/YY1 axis24
Targeting KRAS mutant lung cancer: light at the end of the tunnel23
Autophagy at the intersection of aging, senescence, and cancer23
Molecular profiling of long‐term responders to immune checkpoint inhibitors in advanced non‐small cell lung cancer23
SST gene hypermethylation acts as a pan‐cancer marker for pancreatic ductal adenocarcinoma and multiple other tumors: toward its use for blood‐based diagnosis23
The STAT3‐miR‐223‐TGFBR3/HMGCS1 axis modulates the progression of cervical carcinoma23
RAF dimer inhibition enhances the antitumor activity of MEK inhibitors in K‐RAS mutant tumors23
Rho‐associated protein kinase‐dependent moesin phosphorylation is required for PD‐L1 stabilization in breast cancer23
Cancer‐associated fibroblast migration in non‐small cell lung cancers is modulated by increased integrin α11 expression23
Fluid shear stress activates YAP to promote epithelial–mesenchymal transition in hepatocellular carcinoma23
Histone methyltransferase SETD1A interacts with HIF1α to enhance glycolysis and promote cancer progression in gastric cancer23
Deubiquitinase OTUD6A promotes proliferation of cancer cells via regulating Drp1 stability and mitochondrial fission22
Molecular and clinicopathological characteristics of ROS1‐rearranged non‐small‐cell lung cancers identified by next‐generation sequencing22
Pathological validation and prognostic potential of quantitative MRI in the characterization of pancreas cancer: preliminary experience22
Autophagy inhibits cancer stemness in triple‐negative breast cancer via miR‐181a‐mediated regulation of ATG5 and/or ATG2B22
The evolutionarily conserved long non‐coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms22
Allele‐specific proximal promoter hypomethylation of the telomerase reverse transcriptase gene (TERT) associates with TERT expression in multiple cancers22
What will radiation oncology look like in 2050? A look at a changing professional landscape in Europe and beyond22
Early detection of hepatocellular carcinoma via liquid biopsy: panel of small extracellular vesicle‐derived long noncoding RNAs identified as markers22
TRIP13 promotes metastasis of colorectal cancer regardless of p53 and microsatellite instability status22
Gene expression profiles of breast cancer metastasis according to organ site22
Single‐cell transcriptomics reveal the intratumoral landscape of infiltrated T‐cell subpopulations in oral squamous cell carcinoma22
Lipidomic profiling of exosomes from colorectal cancer cells and patients reveals potential biomarkers22
Multiomics integrative analysis reveals antagonistic roles of CBX2 and CBX7 in metabolic reprogramming of breast cancer22
Prevalence of PRKDC mutations and association with response to immune checkpoint inhibitors in solid tumors21
Cancer‐associated fibroblasts educate normal fibroblasts to facilitate cancer cell spreading and T‐cell suppression21
Epidermal activation of Hedgehog signaling establishes an immunosuppressive microenvironment in basal cell carcinoma by modulating skin immunity21
FUBP1 promotes colorectal cancer stemness and metastasis via DVL1‐mediated activation of Wnt/β‐catenin signaling21
Long non‐coding RNA RACGAP1P promotes breast cancer invasion and metastasis via miR‐345‐5p/RACGAP1‐mediated mitochondrial fission21
Protein palmitoylation in cancer: molecular functions and therapeutic potential21
Serial circulating tumor DNA to predict early recurrence in patients with hepatocellular carcinoma: a prospective study21
Aspirin sensitizes osimertinib‐resistant NSCLC cells in vitro and in vivo via Bim‐dependent apoptosis induction20
The genetic landscape of metaplastic breast cancers and uterine carcinosarcomas20
Platycodin D inhibits autophagy and increases glioblastoma cell death via LDLR upregulation20
Occupational cancer burden: the contribution of exposure to process‐generated substances at the workplace20
Circulating tumor DNA as a biomarker for monitoring early treatment responses of patients with advanced lung adenocarcinoma receiving immune checkpoint inhibitors20
A novel molecular link between HOXA9 and WNT6 in glioblastoma identifies a subgroup of patients with particular poor prognosis20
Epithelial/mesenchymal heterogeneity of high‐grade serous ovarian carcinoma samples correlates with miRNA let‐7 levels and predicts tumor growth and metastasis20
Mutated circulating tumor DNA as a liquid biopsy in lung cancer detection and treatment20
A thiopyrylium salt for PET/NIR‐II tumor imaging and image‐guided surgery20
Ribonucleotide reductase small subunit M2 is a master driver of aggressive prostate cancer20
Molecular testing on bronchial washings for the diagnosis and predictive assessment of lung cancer20
Downregulation of adipose triglyceride lipase by EB viral‐encoded LMP2A links lipid accumulation to increased migration in nasopharyngeal carcinoma20
Somatic mutations and copy number variations in breast cancers with heterogeneous HER2 amplification19
Serum markers improve current prediction of metastasis development in early‐stage melanoma patients: a machine learning‐based study19
FKBP51 and FKBP52 regulate androgen receptor dimerization and proliferation in prostate cancer cells19
Phosphorylation of the androgen receptor at Ser81 is co‐sustained by CDK1 and CDK9 and leads to AR‐mediated transactivation in prostate cancer19
Pre‐analytical factors affecting the establishment of a single tube assay for multiparameter liquid biopsy detection in melanoma patients19
Irradiation‐induced polyploid giant cancer cells are involved in tumor cell repopulation via neosis19
CircATRNL1 activates Smad4 signaling to inhibit angiogenesis and ovarian cancer metastasis via miR‐37819
MYC and therapy resistance in cancer: risks and opportunities19
Optimized low‐dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment19
Defining the dimensions of circulating tumor cells in a large series of breast, prostate, colon, and bladder cancer patients19
Vaccination against HPV: boosting coverage and tackling misinformation19
TERT C228T mutation in non‐malignant bladder urothelium is associated with intravesical recurrence for patients with non‐muscle invasive bladder cancer19
High‐throughput proteomics of breast cancer interstitial fluid: identification of tumor subtype‐specific serologically relevant biomarkers19
Viruses in colorectal cancer19
Platelets are recruited to hepatocellular carcinoma tissues in a CX3CL1‐CX3CR1 dependent manner and induce tumour cell apoptosis18
TRAP1 enhances Warburg metabolism through modulation of PFK1 expression/activity and favors resistance to EGFR inhibitors in human colorectal carcinomas18
E2F1‐activated SPIN1 promotes tumor growth via a MDM2‐p21‐E2F1 feedback loop in gastric cancer18
PIM protein kinases regulate the level of the long noncoding RNA H19 to control stem cell gene transcription and modulate tumor growth18
The PI3K/mTOR inhibitor Gedatolisib eliminates dormant breast cancer cells in organotypic culture, but fails to prevent metastasis in preclinical settings18
The lncRNA ‘UCA1’ modulates the response to chemotherapy of ovarian cancer through direct binding to miR‐27a‐5p and control of UBE2N levels18
Identification of BLNK and BTK as mediators of rituximab‐induced programmed cell death by CRISPR screens in GCB‐subtype diffuse large B‐cell lymphoma18
Lipocalin 2 promotes inflammatory breast cancer tumorigenesis and skin invasion18
A novel prognostic model based on four circulating miRNA in diffuse large B‐cell lymphoma: implications for the roles of MDSC and Th17 cells in lymphoma progression18
Comprehensive cross‐platform comparison of methods for non‐invasive EGFR mutation testing: results of the RING observational trial18
Intracellular matrix Gla protein promotes tumor progression by activating JAK2/STAT5 signaling in gastric cancer17
A novel circular RNA, hsa_circ_0030998 suppresses lung cancer tumorigenesis and Taxol resistance by sponging miR‐55817
Constitutive activation of integrin αvβ3 contributes to anoikis resistance of ovarian cancer cells17
SIK2 represses AKT/GSK3β/β‐catenin signaling and suppresses gastric cancer by inhibiting autophagic degradation of protein phosphatases17
Programmed death‐ligand 1 gene expression is a prognostic marker in early breast cancer and provides additional prognostic value to 21‐gene and 70‐gene signatures in estrogen receptor‐positive disease17
Blood DNA methylation profiles improve breast cancer prediction17
The ZEB2‐dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer17
Integrative analysis of gut microbiome and host transcriptomes reveals associations between treatment outcomes and immunotherapy‐induced colitis17
In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor17
Oncogenic KRAS mutations enhance amino acid uptake by colorectal cancer cells via the hippo signaling effector YAP117
Targeting senescence as an anticancer therapy17
EWI‐2 controls nucleocytoplasmic shuttling of EGFR signaling molecules and miRNA sorting in exosomes to inhibit prostate cancer cell metastasis17
Immune modulation underpins the anti‐cancer activity of HDAC inhibitors17
Overexpression of GLT1D1 induces immunosuppression through glycosylation of PD‐L1 and predicts poor prognosis in B‐cell lymphoma17
Long non‐coding NR2F1‐AS1 is associated with tumor recurrence in estrogen receptor‐positive breast cancers17
Secretogranin II impairs tumor growth and angiogenesis by promoting degradation of hypoxia‐inducible factor‐1α in colorectal cancer17
TGF‐β‐induced IGFBP‐3 is a key paracrine factor from activated pericytes that promotes colorectal cancer cell migration and invasion17
Role of radiation oncology in modern multidisciplinary cancer treatment16
The KRAS/Lin28B axis maintains stemness of pancreatic cancer cells via the let‐7i/TET3 pathway16
Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1‐driven acute lymphoblastic leukemia16
Integrating bulk and single‐cell RNA sequencing reveals cellular heterogeneity and immune infiltration in hepatocellular carcinoma16
KMT2C promoter methylation in plasma‐circulating tumor DNA is a prognostic biomarker in non‐small cell lung cancer16
Metagenomic analysis of primary colorectal carcinomas and their metastases identifies potential microbial risk factors16
Multiplex RNA‐based detection of clinically relevant MET alterations in advanced non‐small cell lung cancer16
Benchmarking HLA genotyping and clarifying HLA impact on survival in tumor immunotherapy16
Cancer‐associated fibroblasts promote tumor progression by lncRNA‐mediated RUNX2/GDF10 signaling in oral squamous cell carcinoma16
Mitochondrial DNA mutations in ageing and cancer16
HRD1 inhibits fatty acid oxidation and tumorigenesis by ubiquitinating CPT2 in triple‐negative breast cancer16
Breast cancer metastasis: immune profiling of lymph nodes reveals exhaustion of effector T cells and immunosuppression16
The miR‐19b‐3p‐MAP2K3‐STAT3 feedback loop regulates cell proliferation and invasion in esophageal squamous cell carcinoma16
Patient‐derived organoids as a preclinical platform for precision medicine in colorectal cancer16
Neuronal Calcium Sensor 1 is up‐regulated in response to stress to promote cell survival and motility in cancer cells16
Genome‐scale CRISPR screening identifies cell cycle and protein ubiquitination processes as druggable targets for erlotinib‐resistant lung cancer15
Clinical potential of circulating free DNA and circulating tumour cells in patients with metastatic non‐small‐cell lung cancer treated with pembrolizumab15
Role of aneuploid circulating tumor cells and CD31+ circulating tumor endothelial cells in predicting and monitoring anti‐angiogenic therapy efficacy in advanced NSCLC15
Neurotensin receptor 1 signaling promotes pancreatic cancer progression15
Norepinephrine‐CREB1‐miR‐373 axis promotes progression of colon cancer15
T2R bitter taste receptors regulate apoptosis and may be associated with survival in head and neck squamous cell carcinoma15
Harnessing data science to advance radiation oncology15
Mechanistic insights into p53‐regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cells15
DDRugging glioblastoma: understanding and targeting the DNA damage response to improve future therapies15
Widespread overexpression from the four DNA hypermethylated HOX clusters in aggressive (IDHwt) glioma is associated with H3K27me3 depletion and alternative promoter usage15
DNA repair as a shared hallmark in cancer and ageing15
CD24 blunts the sensitivity of retinoblastoma to vincristine by modulating autophagy15
Improved prognostication of glioblastoma beyond molecular subtyping by transcriptional profiling of the tumor microenvironment15
Therapeutic targeting with DABIL‐4 depletes myeloid suppressor cells in 4T1 triple‐negative breast cancer model15
Identification and validation of novel DNA methylation markers for early diagnosis of lung adenocarcinoma15
USP35 mitigates endoplasmic reticulum stress‐induced apoptosis by stabilizing RRBP1 in non‐small cell lung cancer15
Promoter methylation of DNA homologous recombination genes is predictive of the responsiveness to PARP inhibitor treatment in testicular germ cell tumors15
Characterization of PHGDH expression in bladder cancer: potential targeting therapy with gemcitabine/cisplatin and the contribution of promoter DNA hypomethylation15
Upregulation of mesothelial genes in ovarian carcinoma cells is associated with an unfavorable clinical outcome and the promotion of cancer cell adhesion15
Cotargeting of miR‐126‐3p and miR‐221‐3p inhibits PIK3R2 and PTEN, reducing lung cancer growth and metastasis by blocking AKT and CXCR4 signalling15
NGS‐based liquid biopsy profiling identifies mechanisms of resistance to ALK inhibitors: a step toward personalized NSCLC treatment15
Effect of p53 and its N‐terminally truncated isoform, Δ40p53, on breast cancer migration and invasion15
Discovery and validation of extracellular vesicle‐associated miRNAs as noninvasive detection biomarkers for early‐stage non‐small‐cell lung cancer14
Genomic and pathological heterogeneity in clinically diagnosed small cell lung cancer in never/light smokers identifies therapeutically targetable alterations14
Acquired small cell lung cancer resistance to Chk1 inhibitors involves Wee1 up‐regulation14
Concordance between TP53 alterations in blood and tissue: impact of time interval, biopsy site, cancer type and circulating tumor DNA burden14
A small molecule targeting CHI3L1 inhibits lung metastasis by blocking IL‐13Rα2‐mediated JNK‐AP‐1 signals14
Molecular genomic features associated with in vitro response of the NCI‐60 cancer cell line panel to natural products14
The Sp1/FOXC1/HOTTIP/LATS2/YAP/β‐catenin cascade promotes malignant and metastatic progression of osteosarcoma14
VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer14
ERK signaling controls productive HIF‐1 binding to chromatin and cancer cell adaptation to hypoxia through HIF‐1α interaction with NPM114
Mitochondrial STAT3 regulates antioxidant gene expression through complex I‐derived NAD in triple negative breast cancer14
PD‐1‐induced T cell exhaustion is controlled by a Drp1‐dependent mechanism14
imPlatelet classifier: image‐converted RNA biomarker profiles enable blood‐based cancer diagnostics14
The RNA‐binding protein MEX3A is a prognostic factor and regulator of resistance to gemcitabine in pancreatic ductal adenocarcinoma14
The MSP‐RON axis stimulates cancer cell growth in models of triple negative breast cancer14
USP22‐mediated deubiquitination of PTEN inhibits pancreatic cancer progression by inducing p21 expression14
SF3B1 mutation in pancreatic cancer contributes to aerobic glycolysis and tumor growth through a PP2A–c‐Myc axis14
Tspan5 promotes epithelial–mesenchymal transition and tumour metastasis of hepatocellular carcinoma by activating Notch signalling14
Tetraspanin 1 promotes endometriosis leading to ovarian clear cell carcinoma14
BAP1 suppresses prostate cancer progression by deubiquitinating and stabilizing PTEN14
Prolonged estrogen deprivation triggers a broad immunosuppressive phenotype in breast cancer cells14
BMP9‐ID1 signaling promotes EpCAM‐positive cancer stem cell properties in hepatocellular carcinoma14
The CHK1 inhibitor MU380 significantly increases the sensitivity of human docetaxel‐resistant prostate cancer cells to gemcitabine through the induction of mitotic catastrophe13
Pan‐cancer analysis reveals sex‐specific signatures in the tumor microenvironment13
FGFR1 clustering with engineered tetravalent antibody improves the efficiency and modifies the mechanism of receptor internalization13
Tumor and germline next generation sequencing in high grade serous cancer: experience from a large population‐based testing program13
Molecular characteristics and tumorigenicity of ascites‐derived tumor cells: mitochondrial oxidative phosphorylation as a novel therapy target in ovarian cancer13
Anti‐pyroptotic function of TGF‐β is suppressed by a synthetic dsRNA analogue in triple negative breast cancer cells13
Genomic characterization of small cell carcinomas of the uterine cervix13
Characterization of fragment sizes, copy number aberrations and 4‐mer end motifs in cell‐free DNA of hepatocellular carcinoma for enhanced liquid biopsy‐based cancer detection13
Development and initial clinical testing of a multiplexed circulating tumor cell assay in patients with clear cell renal cell carcinoma13
Targeting the ubiquitin‐proteasome system in a pancreatic cancer subtype with hyperactive MYC13
Detection of gene mutations and gene–gene fusions in circulating cell‐free DNA of glioblastoma patients: an avenue for clinically relevant diagnostic analysis13
Novel CTRP8‐RXFP1‐JAK3‐STAT3 axis promotes Cdc42‐dependent actin remodeling for enhanced filopodia formation and motility in human glioblastoma cells13
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