OOIR: Observatory of International Research

Papers

(The median citation count of Metabolomics is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
New software tools, databases, and resources in metabolomics: updates from 2020	106
Software tools, databases and resources in metabolomics: updates from 2018 to 2019	69
Untargeted metabolomics of COVID-19 patient serum reveals potential prognostic markers of both severity and outcome	57
Dissemination and analysis of the quality assurance (QA) and quality control (QC) practices of LC–MS based untargeted metabolomics practitioners	54
Metabolic landscape of oral squamous cell carcinoma	45
A review of strategies for untargeted urinary metabolomic analysis using gas chromatography–mass spectrometry	42
The key points in the pre-analytical procedures of blood and urine samples in metabolomics studies	39
Untargeted metabolomics as a diagnostic tool in NAFLD: discrimination of steatosis, steatohepatitis and cirrhosis	37
MetaClean: a machine learning-based classifier for reduced false positive peak detection in untargeted LC–MS metabolomics data	36
SWATH-MS for metabolomics and lipidomics: critical aspects of qualitative and quantitative analysis	35
Salivary metabolomics for the diagnosis of periodontal diseases: a systematic review with methodological quality assessment	32
MetFID: artificial neural network-based compound fingerprint prediction for metabolite annotation	28
Post-mortem changes in metabolomic profiles of human serum, aqueous humor and vitreous humor	27
An untargeted metabolomics strategy to measure differences in metabolite uptake and excretion by mammalian cell lines	25
An LC-QToF MS based method for untargeted metabolomics of human fecal samples	25
Plasma metabolites associated with chronic kidney disease and renal function in adults from the Baltimore Longitudinal Study of Aging	24
Metabolic signatures provide novel insights to Picrorhiza kurroa adaptation along the altitude in Himalayan region	24
Identification of markers of sensory quality in ground coffee: an untargeted metabolomics approach	24
New findings on urinary prostate cancer metabolome through combined GC–MS and 1H NMR analytical platforms	24
Forensic NMR metabolomics: one more arrow in the quiver	23
Lipidomics reveals associations between rice quality traits	22
Environmental lipidomics: understanding the response of organisms and ecosystems to a changing world	22
GlycA, a novel marker for low grade inflammation, reflects gut microbiome diversity and is more accurate than high sensitive CRP in reflecting metabolomic profile	22
Metabolomics on the study of marine organisms	22
The remodel of the “central dogma”: a metabolomics interaction perspective	21

Gas chromatography/mass spectrometry-based metabolite profiling of coffee beans obtained from different altitudes and origins with various postharvest processing	20
An integrated omics approach to investigate summer mortality of New Zealand Greenshell™ mussels	19
Challenges in LC–MS-based metabolomics for Alzheimer’s disease early detection: targeted approaches versus untargeted approaches	19
Serum metabolic fingerprinting of psoriasis and psoriatic arthritis patients using solid-phase microextraction—liquid chromatography—high-resolution mass spectrometry	19
Plasma sphingolipids and risk of cardiovascular diseases: a large-scale lipidomic analysis	19
Evaluation of the use of untargeted metabolomics in the safety assessment of genetically modified crops	18
Metabolite profiling of whiteleg shrimp Litopenaeus vannamei from super-intensive culture in closed aquaculture systems: a recirculating aquaculture system and a hybrid zero water discharge–recirculat	18
Cationic amphiphilic drugs induce elevation in lysoglycerophospholipid levels and cell death in leukemia cells	18
Urine metabolomic analysis for monitoring internal load in professional football players	18
GC/MS-based metabolic profiling for the evaluation of solid state fermentation to improve quality of Arabica coffee beans	17
New markers for sepsis caused by Pseudomonas aeruginosa during burn infection	17
Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines	17
A comparison of high-throughput plasma NMR protocols for comparative untargeted metabolomics	17
Metabolome of canine and human saliva: a non-targeted metabolomics study	17
Sex and race differences of cerebrospinal fluid metabolites in healthy individuals	16
A non-targeted LC–MS metabolic profiling of pregnancy: longitudinal evidence from healthy and pre-eclamptic pregnancies	16
Targeted metabolomics highlights perturbed metabolism in the brain of autism spectrum disorder sufferers	15
Integrating in vitro metabolomics with a 96-well high-throughput screening platform	15
Applying NMR compound identification using NMRfilter to match predicted to experimental data	15
Oxidative stress contributes to cerebral metabolomic profile changes in animal model of blast-induced traumatic brain injury	15
Improving lipid mapping in Genome Scale Metabolic Networks using ontologies	15
Comparative metabolic profiles of total and partial body radiation exposure in mice using an untargeted metabolomics approach	14
MetaboShiny: interactive analysis and metabolite annotation of mass spectrometry-based metabolomics data	14
Metabolomics by UHPLC-HRMS reveals the impact of heat stress on pathogen-elicited immunity in maize	14
Serum metabolomic patterns in young patients with ischemic stroke: a case study	14
Prenatal exposure to poly-/per-fluoroalkyl substances is associated with alteration of lipid profiles in cord-blood	14
Metabolites involved in purine degradation, insulin resistance, and fatty acid oxidation are associated with prediction of Gestational diabetes in plasma	14
Comprehensive lipidomic profiling in serum and multiple tissues from a mouse model of diabetes	14
Metabolomics analysis reveals altered metabolites in lean compared with obese adolescents and additional metabolic shifts associated with hyperinsulinaemia and insulin resistance in obese adolescents:	14
A population-based resource for intergenerational metabolomics analyses in pregnant women and their children: the Generation R Study	13
Malignancy prediction among tissues from Oral SCC patients including neck invasions: a 1H HRMAS NMR based metabolomic study	13
Assessment of the effects of repeated freeze thawing and extended bench top processing of plasma samples using untargeted metabolomics	13
Metabolomic and elemental profiling of human tissue in kidney cancer	13
Comparison of dried blood spot and plasma sampling for untargeted metabolomics	13
The verification of the reliability of a triglyceride–glucose index and its availability as an advanced tool	12
Comprehensive metabolomic profiling of osteosarcoma based on UHPLC-HRMS	12
Workshop report: Toward the development of a human whole stool reference material for metabolomic and metagenomic gut microbiome measurements	12
Metabolic signatures of osteoarthritis in urine using liquid chromatography‐high resolution tandem mass spectrometry	12
Untargeted metabolomics in primary murine bone marrow stromal cells reveals distinct profile throughout osteoblast differentiation	12
Can we trust biomarkers identified using different non-targeted metabolomics platforms? Multi-platform, inter-laboratory comparative metabolomics profiling of lettuce cultivars via UPLC-QTOF-MS	12
Distinctive metabolic profiles between Cystic Fibrosis mutational subclasses and lung function	12
Combining lipidomics and machine learning to measure clinical lipids in dried blood spots	12
Use of information dependent acquisition mass spectra and sequential window acquisition of all theoretical fragment-ion mass spectra for fruit juices metabolomics and authentication	11
Disease progression-associated alterations in fecal metabolites in SAMP1/YitFc mice, a Crohn’s disease model	11
Chemotaxonomic profiling of fungal endophytes of Solanum mauritianum (alien weed) using gas chromatography high resolution time-of-flight mass spectrometry (GC-HRTOF-MS)	11
Differential correlation network analysis identified novel metabolomics signatures for non-responders to total joint replacement in primary osteoarthritis patients	11
Spatially resolved metabolomic characterization of muscle invasive bladder cancer by mass spectrometry imaging	11
One mutation, three phenotypes: novel metabolic insights on MELAS, MIDD and myopathy caused by the m.3243A > G mutation	11
Optimized sample preparation for fecal volatile organic compound analysis by gas chromatography–mass spectrometry	10
A novel method to detect intracellular metabolite alterations in MCF-7 cells by doxorubicin induced cell death	10

Precise pathological classification of non-small cell lung adenocarcinoma and squamous carcinoma based on an integrated platform of targeted metabolome and lipidome	10
Cultivar, site or harvest date: the gordian knot of wine terroir	10
Potential biomarkers identified in plasma of patients with gestational diabetes mellitus	10
On sample preparation methods for fermented beverage VOCs profiling by GCxGC-TOFMS	10
Metabolic changes in early neonatal life: NMR analysis of the neonatal metabolic profile to monitor postnatal metabolic adaptations	10
Molecular networking based LC/MS reveals novel biotransformation products of green coffee by ex vivo cultures of the human gut microbiome	9
Method comparison of HPLC-ninhydrin-photometry and UHPLC-PITC-tandem mass spectrometry for serum amino acid analyses in patients with complex congenital heart disease and controls	9
Metabolite profiling reveals a connection between aldehyde dehydrogenase 1A3 and GABA metabolism in breast cancer metastasis	9
Circulating trace elements for the prediction of preeclampsia and small for gestational age babies	9
Plasma metabolomic profile in prostatic intraepithelial neoplasia and prostate cancer and associations with the prostate-specific antigen and the Gleason score	9
Metabolomics analyses in non-diabetic middle-aged individuals reveal metabolites impacting early glucose disturbances and insulin sensitivity	9
Plasma and stool metabolomics to identify microbiota derived-biomarkers of metabolic dysfunction-associated fatty liver disease: effect of PNPLA3 genotype	9
Altered metabolic pathways in a transgenic mouse model suggest mechanistic role of amyloid precursor protein overexpression in Alzheimer’s disease	9
Specificity of metabolic colorectal cancer biomarkers in serum through effect size	8
Urine tricarboxylic acid cycle signatures of early-stage diabetic kidney disease	8
Rapid HILIC-Z ion mobility mass spectrometry (RHIMMS) method for untargeted metabolomics of complex biological samples	8
Metabolomics profiling predicts outcome of tocilizumab in rheumatoid arthritis: an exploratory study	8
Metabolic fingerprint of progression of chronic hepatitis B: changes in the metabolome and novel diagnostic possibilities	8
WaveICA 2.0: a novel batch effect removal method for untargeted metabolomics data without using batch information	8
The plasma metabolome of Atlantic salmon as studied by 1H NMR spectroscopy using standard operating procedures: effect of aquaculture location and growth stage	8
Learning about microbial language: possible interactions mediated by microbial volatile organic compounds (VOCs) and relevance to understanding Malassezia spp. metabolism	8
Tissue metabolic profiling shows that saccharopine accumulates during renal ischemic-reperfusion injury, while kynurenine and itaconate accumulate in renal allograft rejection	8
Impact of the used solvent on the reconstitution efficiency of evaporated biosamples for untargeted metabolomics studies	8
Untargeted fecal metabolome analysis in obese dogs after weight loss achieved by feeding a high-fiber-high-protein diet	8
Sarcopenic metabolomic profile reflected a sarcopenic phenotype associated with amino acid and essential fatty acid changes	8
Metabolomic signature of amino acids in plasma of patients with non-segmental Vitiligo	8
Renin-angiotensin system inhibition reverses the altered triacylglycerol metabolic network in diabetic kidney disease	8
Associations of maternal bisphenol urine concentrations during pregnancy with neonatal metabolomic profiles	7
Metabolic characteristics of plasma bile acids in patients with intrahepatic cholestasis of pregnancy-mass spectrometric study	7
Salivary metabolite levels in perinatally HIV-infected youth with periodontal disease	7
A strategy for advancing for population-based scientific discovery using the metabolome: the establishment of the Metabolomics Society Metabolomic Epidemiology Task Group	7
Metabolic profiles identify circulating biomarkers associated with heart failure in young single ventricle patients	7
Fatty acid metabolism and colon cancer protection by dietary methyl donor restriction	7
Glycerophospholipid and detoxification pathways associated with small for gestation age pathophysiology: discovery metabolomics analysis in the SCOPE cohort	7
Interpreting the lipidome: bioinformatic approaches to embrace the complexity	7
Longitudinal analysis of the salivary metabolome of breast-fed and formula-fed infants over the first year of life	7
Shrimp count size: GC/MS-based metabolomics approach and quantitative descriptive analysis (QDA) reveal the importance of size in white leg shrimp (Litopenaeus vannamei)	7
NMR metabolomic profiles associated with long-term risk of prostate cancer	7
Serum metabolomics analysis reveals that weight loss in obese dogs results in a similar metabolic profile to dogs in ideal body condition	7
Changes in lipid profiles of epileptic mouse model	7
Osmolality-based normalization enhances statistical discrimination of untargeted metabolomic urine analysis: results from a comparative study	7
Metabolomics and hormonomics to crack the code of filbert growth	7
Time-course analysis of Streptococcus sanguinis after manganese depletion reveals changes in glycolytic and nucleic acid metabolites	7