OOIR: Observatory of International Research

Papers

(The median citation count of International Journal of Peptide Research and Therapeutics is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Role of Polypeptide Inflammatory Biomarkers in the Diagnosis and Monitoring of COVID-19	79
Synthetic Antimicrobial Peptide Polybia MP-1 (Mastoparan) Inhibits Growth of Antibiotic Resistant Pseudomonas aeruginosa Isolates From Mastitic Cow Milk	67
Anticipation of Antigenic Sites for the Goal of Vaccine Designing Against Nipah Virus: An Immunoinformatics Inquisitive Quest	53
ACE2 Peptide Fragment Interaction with Different S1 Protein Sites	45
Evaluation of Functional Properties of Wheat Germ Protein Hydrolysates and Its Effect on Physicochemical Properties of Frozen Yogurt	38
In-Silico Validation of Prosopis ciniraria Therapeutic Peptides Against Fungal Cell Wall: Better Treatment Strategy for Fungal Diseases	36
Membrane Bound Aminopeptidase B of a Potential Probiotic Pediococcus acidilactici NCDC 252: Purification, Physicochemical and Kinetic Characterization	29
Glutathione Encapsulation in Core-Shell Drug Nanocarriers (Polymersomes and Niosomes) Prevents Advanced Glycation End-products Toxicities	23
Secretory Expression of Human Vascular Endothelial Growth Factor (VEGF165) in Kluyveromyces lactis and Characterization of Its Biological Activity	23
Stability of Oligopeptides in Solution. Proteolytic Digestion and Potential Dimerization Process	20
Immunoinformatics Insights into the Internalin A and B Proteins to Design a Multi-Epitope Subunit Vaccine for L. monocytogenes	18
l-asparaginase: Need for an Expedition from an Enzymatic Molecule to Antimicrobial Drug	17
Pierce into Structural Changes of Interactions Between Mutated Spike Glycoproteins and ACE2 to Evaluate Its Potential Biological and Therapeutic Consequences	16
In-Silico Design of a Novel Tridecapeptide Targeting Spike Protein of SARS-CoV-2 Variants of Concern	16
Recombinant Expression and Antibacterial Properties of BmTXKS2 Venom Peptide in Fusion with GST	16
Design and In Silico Evaluation of a Novel Cyclic Disulfide-Rich anti-VEGF Peptide as a Potential Antiangiogenic Drug	15
Pulse Derived Bioactive Peptides as Novel Nutraceuticals: A Review	15
Structural Characteristics, Prokaryotic Expression and Activity Analysis of Antimicrobial Peptide ALFPm10 from Penaeus monodon	15
Machine Learning for the Cleaner Production of Antioxidant Peptides	15
Immuno-Affinity Study of Oxidative Tyrosine Containing Peptides	14
Therapeutic Potential of Antimicrobial Peptides for Wound Healing	14
Peripheral Administration of an Opioid Peptide Analog Ameliorates Morphine-Produced Hyperalgesia in a Spared Nerve Injury Model	13
Correction to: Investigation of Fluorine-18 Labelled Peptides for Binding to Cholecystokinin-2 Receptors with High Affinity	13
Chikungunya Virus Vaccine Development: Through Computational Proteome Exploration for Finding of HLA and cTAP Binding Novel Epitopes as Vaccine Candidates	13
Preliminary Study on the Antibacterial and Cytotoxic Effects of the Synthetic New Peptide NJP9-A	13

Production of Soluble Bioactive NmDef02 Plant Defensin in Escherichia coli	13
The Stability of Food Bioactive Peptides in Blood: An Overview	13
Evaluation the Therapeutic Index of Recombinant Antimicrobial S3 Tetramer-Peptides Expressed in E. coli	12
Molecular Characterization and Designing of a Novel Multiepitope Vaccine Construct Against Pseudomonas aeruginosa	12
In silico Design and Characterization of Multi-epitopes Vaccine for SARS-CoV2 from Its Spike Protein	12
Bioactivities of In Vitro Transepithelial Transported Peptides from Cooked Chicken Breast	12
Involvement of Cathepsins Protein in Mycobacterial Infection and Its Future Prospect as a Therapeutic Target	12
Potential Efficacy of Biofilm-Forming Biosurfactant Bacillus firmus HussainT-Lab.66 Against Rhizoctonia solani and Mass Spectrometry Analysis of its Metabolites	11
Design of Monovalent and Chimeric Tetravalent Dengue Vaccine Using an Immunoinformatics Approach	11
A Mini-Review on Potential of Neuropeptides as Future Therapeutics	11
Environmentally Conscious In-Water Peptide Synthesis Using Boc Strategy	11
In-Silico Vaccine Design Based on a Novel Vaccine Candidate Against Infections Caused by Acinetobacter baumannii	11
In Silico Analysis of Potential Outer Membrane Beta-Barrel Proteins in Aeromonas hydrophila Pangenome	11
Evaluation of Cell-Penetrating Peptides as Mucosal Immune Enhancers for Nasal Vaccination	10
Expression and Characterization of a Potent Long-Acting GLP-1 Receptor Like Agonist, Exendin-4-Fc	10
Detecting the Dominant T and B Epitopes of Klebsiella pneumoniae Ferric Enterobactin Protein (FepA) and Introducing a Single Epitopic Peptide as Vaccine Candidate	10
A Comprehensive in Silico Analysis for Identification of Immunotherapeutic Epitopes of HPV-18	10
Computational Design and Analysis of a Multi-epitope Against Influenza A virus	9
Quest for Novel Preventive and Therapeutic Options Against Multidrug-Resistant Pseudomonas aeruginosa	9
Immunoinformatics Approach to Design a Novel Subunit Vaccine Against Visceral Leishmaniasis	9
New Computational Approach for Peptide Vaccine Design Against SARS-COV-2	8
Development of ULYSSIS, a Tool for the Biosynthesis of Cyclotides and Cyclic Knottins	8
Linear and Branched Forms of Short Antimicrobial Peptide-IRK Inhibit Growth of Multi Drug Resistant Staphylococcus aureus Isolates from Mastitic Cow Milk	8
Antibacterial Activity of RM12, a Tachykinin Derivative, Against Pseudomonas aeruginosa	8
Cyclic Dodecapeptide Induces Cell Death Through Membrane–Peptide Interactions in Breast Cancer Cells	8
Correction to: Galanin Peptides Alleviate Myocardial Ischemia/Reperfusion Injury by Reducing Reactive Oxygen Species Formation	8
PeptCreatR: A Web App for Unique Peptides in Human	7
Head and Neck Squamous Cell Carcinoma: Risk Factors, Molecular Alterations, Immunology and Peptide Vaccines	7
Wasp Venom Peptide (Polybia MP-1) Shows Antimicrobial Activity Against Multi Drug Resistant Bacteria Isolated from Mastitic Cow Milk	7
Breast Tumor Targeting in Mice Bearing 4T1 Tumor with Labeled CXCR4 Antagonist Analogue	7
Deciphering the Limitations and Antibacterial Mechanism of Cruzioseptins	7
Novel Antiproliferative Tripeptides Inhibit AP-1 Transcriptional Complex	7
Peptide Affinity Chromatography Applied to Therapeutic Antibodies Purification	7
Lactic Acid Bacteria Bacteriocin, an Antimicrobial Peptide Effective Against Multidrug Resistance: a Comprehensive Review	6
Hydrophobic Residues Confer the Helicity and Membrane Permeability of Ocellatin-1 Antimicrobial Peptide Scaffold Towards Therapeutics	6
Phα1β is a Promising Neuroprotective Peptide from the Phoneutria nigriventer ‘Armed’ Spider	6
Enhanced Activation of Atrial Natriuretic Peptide (ANP) and Natriuretic Peptide Receptor-A (NPRA) in Chronic Cigarette Smoke-Induced Lung Inflammation in Experimental Rats	6
Identifying Dipeptidyl Peptidase-IV Inhibitory Peptides Based on Correlation Information of Physicochemical Properties	6
Mycobacterium tuberculosis Rv0292 Protein Peptides Could be Included in a Synthetic Anti-tuberculosis Vaccine	6
Total Synthesis of Novel Antimicrobial β-Hairpin Capitellacin Via Rapid Flow-Based SPPS Assembly and Regioselective On-Resin Disulfide Cyclisation	6
Antidiabetic Potential of Protein Hydrolysates and Peptide Fractions from Lima Bean (Phaseolus lunatus L): An In Vitro Study	6
Viral 3CLpro as a Target for Antiviral Intervention Using Milk-Derived Bioactive Peptides	6
In Silico Analysis of Inhibiting Papain-like Protease from SARS-CoV-2 by Using Plant-Derived Peptides	6
HL-7 and HL-10 Peptides Stimulate Insulin Secretion in the INS-1 Insulinoma Cell Line through Incretin-Dependent Pathway and Increasing the Glucose Uptake in L6 Myoblast	5
Subtractive Proteomics and Immuno-informatics Approaches for Multi-peptide Vaccine Prediction Against Klebsiella oxytoca and Validation Through In Silico Expression	5
Design of Tripeptides as a Competitive Inhibitor for HMG-CoA Reductase	5
VirVACPRED: A Web Server for Prediction of Protective Viral Antigens	5
Enhanced Production of Iturin A-2 Generated from Bacillus velezensis T701 and the Antitumor Activity of Iturin A-2 against Human Gastric Carcinoma Cells	5
The Interaction of Possible Anti-AD ASA-NAP Peptide Conjugate with Tubulin: A Theoretical and Experimental Insight	5
Crab Pentapeptide and Its Anti-inflammatory Activity on Macrophage Cells	5

Nano Defensin: A Promising Antibacterial Agent Against Colorectal Cancer Related Bacteria	4
Prophylactic Application of MA-[d-Leu-4]-OB3, a Small Molecule Synthetic Peptide Leptin Mimetic, Prevents or Slows the Progression of Obesity, Insulin Resistance, and Cognitive Impairment in a Mouse M	4
Production and Evaluation of In-vitro and In-vivo Effects of P28-IL24, a Promising Anti-breast Cancer Fusion Protein	4
Arylglycine: A Focus on Amino Acid Preparation and Peptide Synthesis	4
Recombinant Expression of a Plant-Derived Dimeric Antifungal Peptide (DiSkh-AMP1) Joined by a Flexible Linker in Escherichia coli and Evaluation of Its Biological Activity In Vitro	4
Extracellular Calcium Contributes to Orexin-Induced Postsynaptic Excitation of the Rat Locus Coeruleus Neurons	4
In Vitro and In Vivo Investigation of the Radiation-Sensitizing Effects of Melittin in Breast Cancer Cells	4
A Comprehensive Review on the Anticancer Potential of Bacteriocin: Preclinical and Clinical Studies	4
Integrated Multi-omics, Virtual Screening and Molecular Docking Analysis of Methicillin-Resistant Staphylococcus aureus USA300 for the Identification of Potential Therapeutic Targets: An In-Silico App	4
Exploring Onchocerca volvulus Cysteine Protease Inhibitor for Multi-epitope Subunit Vaccine Against Onchocerciasis: An Immunoinformatics Approach	4
Biofilm Effects of the Soil Bacillus cereus Metabolites: Isolation, Characterization and Antimicrobial Activity Against Methicillin-Resistant Staphylococcus aureus	4
Immunoinformatics Construction of B Cell Epitope-Based Hypoallergenic Der f 34 Vaccine for Immunotherapy of House Dust Mite Allergy	4
Exploring Structural Mechanism of COVID-19 Treatment with Glutathione as a Potential Peptide Inhibitor to the Main Protease: Molecular Dynamics Simulation and MM/PBSA Free Energy Calculations Study	4