OOIR: Observatory of International Research

Papers

(The TQCC of Protein Journal is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
The Proteostasis of Thymic Stromal Cells in Health and Diseases	39
Investigating a putative transcriptional regulatory protein encoded by Rv1719 gene of Mycobacterium tuberculosis	27
Infrared Spectral Patterns of Thyroglobulin Bearing Thyroiditogenic Epitopes	14
Up-Regulated Proteins Have More Protein–Protein Interactions than Down-Regulated Proteins	13
Utilisation of Carbon Quantum Dots from Hazelnut Husk for Folic Acid (FA) Detection: An Innovative Approach	13
Structural Changes of Apolipoprotein A-I Caused by Hydroxyethyl Starch 130/0.4 Reveals Potential Toxic Mechanisms	13
Effect of Organic Solvents on the Activity, Stability and Secondary Structure of asclepain cI, Using FTIR and Molecular Dynamics Simulations	13
Involvement of the non-active site Residues in the Catalytic Activity of NDM-4 Metallo beta-lactamase	13
Impression of Insect’s Proteolytic Enzyme Cocoonase and Its Application: A Comprehensive Review	12
Rational Design, Synthesis, and Computational Investigation of Dihydropyridine [2,3-d] Pyrimidines as Polyphenol Oxidase Inhibitors with Improved Potency	12
Crystal Structure of a Thioredoxin-like Ferredoxin Encoded Within a Cobalamin Biosynthetic Operon of Rhodobacter capsulatus	12
A New Combination: Anti Glypican-3 scFv and Diphtheria Toxin with the Best Flexible Linker	11
Identification of Potential RNAi Targets for Cotton Mealybug (Phenacoccus solenopsis Tinsley) Management	11
Kennedy Epitope (KE)-dependent Retrograde Transport of Efficiently Cleaved HIV-1 Envelopes (Envs) and its Effect on Env Cell Surface Expression and Viral Particle Formation	10
Toxoplasma Gondii Importin α Shows Weak Auto-Inhibition	10
Identification of Alternatively Spliced Novel Isoforms of Human HSPB8 Gene	10
Inhibition of Listeria Monocytogenes HtrA Protease with Camostat, Gabexate and Nafamostat Mesylates and the Binding Mode of the Inhibitors	9
N-Linked Glycoproteome Analysis of Diosorea alata Tuber Shows Atypical Glycosylation and Indicates Central Role of Glycosylated Proteins in Tuber Maturation	9
Heterologous Production of Antimicrobial Peptides: Notes to Consider	9
Thermodynamic Evolution of a Metamorphic Protein: A Theoretical-Computational Study of Human Lymphotactin	9
Molecular Modeling and Optimization of Type II E.coli l-Asparginase Activity by in silico Design and in vitro Site-directed Mutagenesis	9
Physicochemical Characterization and In Vitro Digestibility Study of an In Silico Designed Recombinant Protein Enriched with Large Neutral Amino Acids and Lacking Phenylalanine for Phenylketonuria	9
Selection and Molecular Response of AHL-lactonase (aiiA) Producing Bacillus sp. Under Penicillin G-induced Conditions	8
Delineation of Recombinant Cestode Phosphoenolpyruvate Carboxykinase Activity Co-expressed with Molecular Chaperones	8
Domain Shuffling and Site-Saturation Mutagenesis for the Enhanced Inhibitory Potential of Amaranthaceae α-Amylase Inhibitors	8

Soluble Expression of Antimicrobial Peptide BSN-37 from Escherichia coli by SUMO Fusion Technology	8
Use of 2D FFT and DTW in Protein Sequence Comparison	7
Ferguson Plot Analysis of Chaperone ClpB from Moderate Halophile	7
Proteomic Analysis of Serum Samples in Ovulatory Polycystic Ovary Syndrome and Construction of a Protein Interaction Pathway	7
A Phagosomally Expressed Gene, rv0428c, of Mycobacterium tuberculosis Demonstrates Acetyl Transferase Activity and Plays a Protective Role Under Stress Conditions	7
gmXtal: Cooking Crystals with GROMACS	7
Expression and purification of recombinant human CCL5 and its biological characterization	7
Multiple Protein Profiler 1.0 (MPP): A Webserver for Predicting and Visualizing Physiochemical Properties of Proteins at the Proteome Level	7
Unraveling the interaction between a glycolytic regulator protein EhPpdk and an anaphase promoting complex protein EhApc10: yeast two hybrid screening, in vitro binding assays and molecular simulation	7
Role of ionic liquids on stabilization of therapeutic proteins and model proteins	7
Endoplasmic Reticulum Stress: Implications in Diseases	7
A Novel Glucose-6-Phosphate Isomerase Exists in Chicken Breast Meat: A Selenium-Containing Enzyme that Should Be Re-recognized Through New Eyes	6
Methylglyoxal-Induced Modification of Hen Egg White Lysozyme: Detection of Advanced Glycation End Products by High Resolution Mass Spectrometry	6
Exploring Wheat Leaf Urease for a Sustainable Approach: Purification, Kinetics, and Thermal Stability Characterization	6
Molecular and Computational Analysis Identify Statins as Selective Inhibitors of Human Butyrylcholinesterase	6
Prediction of Solubility of Proteins in Escherichia coli Based on Functional and Structural Features Using Machine Learning Methods	6
Next Generation Sequencing for Potential Regulated Genes and Micro-RNAs of Early Growth Response-1 in the Esophageal Squamous Cell Carcinoma	6
Antemortem Stress Regulates Postmortem Glycolysis in Muscle by Deacetylation of Pyruvate Kinase M1 at K141	6
Engineering Human Pancreatic RNase 1 as an Immunotherapeutic Agent for Cancer Therapy Through Computational and Experimental Studies	6
Live Cell Protein Imaging of Tandem Complemented-GFP11-Tagged Coiled-Coil Domain-Containing Protein-124 Identifies this Factor in G3BP1-Induced Stress-Granules	6
SAXS Analysis and Characterization of Anticancer Activity of PNP-UDP Family Protein from Putranjiva roxburghii	6
Biochemical Characterization of Novel Phenylalanine Ammonia-Lyase from Spirulina CPCC-695	6
Immobilization of Ene Reductase in Polyvinyl Alcohol Hydrogel	5
Investigating the Protective Role of Biochaga Drug on Structural Changes of Bovine Serum Albumin in the Presence of Methyl tert-butyl Ether	5
Editor-in-Chief’s Introduction	5
Identification of Protein–Protein Interaction Associated Functions Based on Gene Ontology	5
A Machine Learning Approach to Identify C Type Lectin Domain (CTLD) Containing Proteins	5
Amine Group Surface-Functionalized Carbon Quantum Dots Exhibit Anti-amyloidogenic Effects Towards Hen Egg White Lysozyme by Inducing Formation of Nontoxic Spherical Aggregates	5
Functional Characterization of Recombinant Endo-Levanase (LevBk) from Bacillus koreensis HL12 on Short-Chain Levan-Type Fructooligosaccharides Production	5
Improved Protein Real-Valued Distance Prediction Using Deep Residual Dense Network (DRDN)	5
On the Path to Optimal Alchemistry	5
A Novel C-Terminal Small Tail Provides Thermostability of FeSOD Implying a New Mechanism of Protein Heat Resistance	5
Mechanistic In-Silico Insights into the Anti-quorum Sensing Potential of Coumaric Acid and Syringic Acid in Serratia marcescens with Invitro Analysis	5
A Retrospective on the Development of Methods for the Analysis of Protein Conformational Ensembles	5
HIV Protease Hinge Region Insertions at Codon 38 Affect Enzyme Kinetics, Conformational Stability and Dynamics	4
Exploring Acoustic Detection of α-Synuclein Fibrils	4
Unveiling the Immunostimulatory Potential of the HSPA1A Mini-Chaperones Compared to the HSPA1A and HSP27 Chaperones: In Silico and In Vitro Insights for Vaccine Development	4
Chemical Modification of the Amino Groups of Human Insulin: Investigating Structural Properties and Amorphous Aggregation of Acetylated Species	4
The complex landscape of intracellular signalling in protein modification under hyperglycaemic stress leading to metabolic disorders	4
Inhibitor Action of Unsaturated Fatty Acids on Equine Serum Butyrylcholinesterase	4
Targeting Aminoglycoside Acetyltransferase Activity of Mycobacterium tuberculosis (H37Rv) Derived Eis (Enhanced Intracellular Survival) Protein with Quercetin	4
Rational Design and Production of Bioactive Analogs of Recombinant Human Keratinocyte Growth Factor (rhKGF) with Reduced Aggregation Propensity	4
A Non-competitive Serpin-Like Thrombin Inhibitor Isolated from Moringa oleifera Exhibit a High Affinity for Thrombin	4
Equilibrium Between Dimeric and Monomeric Forms of Human Epidermal Growth Factor is Shifted Towards Dimers in a Solution	4
Significance of Sequence Features in Classification of Protein–Protein Interactions Using Machine Learning	4
Probing Dual Covalent Irreversible Inhibition of EGFR/FGFR4 by Electrophilic-Based Natural Compounds to Overcome Resistance and Enhance Combination Therapeutic Potentials and Management of Hepatocellu	4
Enhanced Substrate Specificity of Thermostable Cytochrome P450 CYP175A1 by Site Saturation Mutation on Tyrosine 68	4
Role Transformation of HSPA8 to Heme-peroxidase After Binding Hemin to Catalyze Heme Polymerization	4
Molecular and Enzymatic Characterization of 9-Cis-epoxycarotenoid Dioxygenases from Mulberry	4
Interaction of Cecropin A (1–7) Analogs with DNA Analyzed by Multi-spectroscopic Methods	4

Enzymatic Characterization and Coenzyme Specificity Conversion of a Novel Dimeric Malate Dehydrogenase from Bacillus subtilis