OOIR: Observatory of International Research

Papers

(The TQCC of Protein Journal is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
The Proteostasis of Thymic Stromal Cells in Health and Diseases	66
The Structure Biology of Tau and Clue for Aggregation Inhibitor Design	36
Investigating a putative transcriptional regulatory protein encoded by Rv1719 gene of Mycobacterium tuberculosis	32
Effect of Organic Solvents on the Activity, Stability and Secondary Structure of asclepain cI, Using FTIR and Molecular Dynamics Simulations	27
Involvement of the non-active site Residues in the Catalytic Activity of NDM-4 Metallo beta-lactamase	20
Utilisation of Carbon Quantum Dots from Hazelnut Husk for Folic Acid (FA) Detection: An Innovative Approach	17
Impression of Insect’s Proteolytic Enzyme Cocoonase and Its Application: A Comprehensive Review	16
Infrared Spectral Patterns of Thyroglobulin Bearing Thyroiditogenic Epitopes	14
Up-Regulated Proteins Have More Protein–Protein Interactions than Down-Regulated Proteins	13
Rational Design, Synthesis, and Computational Investigation of Dihydropyridine [2,3-d] Pyrimidines as Polyphenol Oxidase Inhibitors with Improved Potency	13
A New Combination: Anti Glypican-3 scFv and Diphtheria Toxin with the Best Flexible Linker	12
A Minireview on Temperature Dependent Protein Conformational Sampling	12
Identification of Alternatively Spliced Novel Isoforms of Human HSPB8 Gene	11
Kennedy Epitope (KE)-dependent Retrograde Transport of Efficiently Cleaved HIV-1 Envelopes (Envs) and its Effect on Env Cell Surface Expression and Viral Particle Formation	11
N-Linked Glycoproteome Analysis of Diosorea alata Tuber Shows Atypical Glycosylation and Indicates Central Role of Glycosylated Proteins in Tuber Maturation	11
Thermodynamic Evolution of a Metamorphic Protein: A Theoretical-Computational Study of Human Lymphotactin	10
Crystal Structure of a Thioredoxin-like Ferredoxin Encoded Within a Cobalamin Biosynthetic Operon of Rhodobacter capsulatus	10
Inhibition of Listeria Monocytogenes HtrA Protease with Camostat, Gabexate and Nafamostat Mesylates and the Binding Mode of the Inhibitors	9
Toxoplasma Gondii Importin α Shows Weak Auto-Inhibition	9
Soluble Expression of Antimicrobial Peptide BSN-37 from Escherichia coli by SUMO Fusion Technology	9
Physicochemical Characterization and In Vitro Digestibility Study of an In Silico Designed Recombinant Protein Enriched with Large Neutral Amino Acids and Lacking Phenylalanine for Phenylketonuria	9
Heterologous Production of Antimicrobial Peptides: Notes to Consider	9
gmXtal: Cooking Crystals with GROMACS	8
Domain Shuffling and Site-Saturation Mutagenesis for the Enhanced Inhibitory Potential of Amaranthaceae α-Amylase Inhibitors	8
Expression and purification of recombinant human CCL5 and its biological characterization	8

Selection and Molecular Response of AHL-lactonase (aiiA) Producing Bacillus sp. Under Penicillin G-induced Conditions	8
Molecular Modeling and Optimization of Type II E.coli l-Asparginase Activity by in silico Design and in vitro Site-directed Mutagenesis	8
Role of ionic liquids on stabilization of therapeutic proteins and model proteins	7
A Phagosomally Expressed Gene, rv0428c, of Mycobacterium tuberculosis Demonstrates Acetyl Transferase Activity and Plays a Protective Role Under Stress Conditions	7
Unraveling the interaction between a glycolytic regulator protein EhPpdk and an anaphase promoting complex protein EhApc10: yeast two hybrid screening, in vitro binding assays and molecular simulation	7
Prediction of the Mannose-Binding Site in the Agaricus bisporus Mannose-Binding Protein	7
Multiple Protein Profiler 1.0 (MPP): A Webserver for Predicting and Visualizing Physiochemical Properties of Proteins at the Proteome Level	7
Protein Production and Purification of a Codon-Optimized Human NGN3 Transcription Factor from E. coli	7
Use of 2D FFT and DTW in Protein Sequence Comparison	7
Ferguson Plot Analysis of Chaperone ClpB from Moderate Halophile	7
Endoplasmic Reticulum Stress: Implications in Diseases	6
Live Cell Protein Imaging of Tandem Complemented-GFP11-Tagged Coiled-Coil Domain-Containing Protein-124 Identifies this Factor in G3BP1-Induced Stress-Granules	6
Antemortem Stress Regulates Postmortem Glycolysis in Muscle by Deacetylation of Pyruvate Kinase M1 at K141	6
A Novel Glucose-6-Phosphate Isomerase Exists in Chicken Breast Meat: A Selenium-Containing Enzyme that Should Be Re-recognized Through New Eyes	6
Glioma-Targeted Therapeutics: Computer-Aided Drug Design Prospective	6
Molecular and Computational Analysis Identify Statins as Selective Inhibitors of Human Butyrylcholinesterase	6
Engineering Human Pancreatic RNase 1 as an Immunotherapeutic Agent for Cancer Therapy Through Computational and Experimental Studies	6
Prediction of Solubility of Proteins in Escherichia coli Based on Functional and Structural Features Using Machine Learning Methods	6
Immobilization of Ene Reductase in Polyvinyl Alcohol Hydrogel	6
Biochemical Characterization of Novel Phenylalanine Ammonia-Lyase from Spirulina CPCC-695	6
Proteomic Profile of Sperm in Infertile Males Reveals Changes in Metabolic Pathways	5
SAXS Analysis and Characterization of Anticancer Activity of PNP-UDP Family Protein from Putranjiva roxburghii	5
The Kringle of Life	5
Improved Protein Real-Valued Distance Prediction Using Deep Residual Dense Network (DRDN)	5
A Machine Learning Approach to Identify C Type Lectin Domain (CTLD) Containing Proteins	5
Amine Group Surface-Functionalized Carbon Quantum Dots Exhibit Anti-amyloidogenic Effects Towards Hen Egg White Lysozyme by Inducing Formation of Nontoxic Spherical Aggregates	5
Next Generation Sequencing for Potential Regulated Genes and Micro-RNAs of Early Growth Response-1 in the Esophageal Squamous Cell Carcinoma	5
On the Path to Optimal Alchemistry	5
Identification of Protein–Protein Interaction Associated Functions Based on Gene Ontology	5
Investigating the Protective Role of Biochaga Drug on Structural Changes of Bovine Serum Albumin in the Presence of Methyl tert-butyl Ether	4
Recombinant Production of Bovine Enteropeptidase Light Chain in SHuffle® T7 Express and Optimization of Induction Parameters	4
Molecular and Enzymatic Characterization of 9-Cis-epoxycarotenoid Dioxygenases from Mulberry	4
Targeting Aminoglycoside Acetyltransferase Activity of Mycobacterium tuberculosis (H37Rv) Derived Eis (Enhanced Intracellular Survival) Protein with Quercetin	4
Probing Dual Covalent Irreversible Inhibition of EGFR/FGFR4 by Electrophilic-Based Natural Compounds to Overcome Resistance and Enhance Combination Therapeutic Potentials and Management of Hepatocellu	4
Exploring Acoustic Detection of α-Synuclein Fibrils	4
Editor-in-Chief’s Introduction	4
Role Transformation of HSPA8 to Heme-peroxidase After Binding Hemin to Catalyze Heme Polymerization	4
Design and Analysis of a Mutant form of the Ice-Binding Protein from Choristoneura fumiferana	4
Consideration on Efficient Recombinant Protein Production: Focus on Substrate Protein-Specific Compatibility Patterns of Molecular Chaperones	4
Enzymatic Characterization and Coenzyme Specificity Conversion of a Novel Dimeric Malate Dehydrogenase from Bacillus subtilis	4
Rational Design and Production of Bioactive Analogs of Recombinant Human Keratinocyte Growth Factor (rhKGF) with Reduced Aggregation Propensity	4
Functional Characterization of Recombinant Endo-Levanase (LevBk) from Bacillus koreensis HL12 on Short-Chain Levan-Type Fructooligosaccharides Production	4
Enhanced Substrate Specificity of Thermostable Cytochrome P450 CYP175A1 by Site Saturation Mutation on Tyrosine 68	4
The complex landscape of intracellular signalling in protein modification under hyperglycaemic stress leading to metabolic disorders	4
Chemical Modification of the Amino Groups of Human Insulin: Investigating Structural Properties and Amorphous Aggregation of Acetylated Species	4
HIV Protease Hinge Region Insertions at Codon 38 Affect Enzyme Kinetics, Conformational Stability and Dynamics	4
Inhibitor Action of Unsaturated Fatty Acids on Equine Serum Butyrylcholinesterase	4
A Retrospective on the Development of Methods for the Analysis of Protein Conformational Ensembles	4