OOIR: Observatory of International Research

Papers

(The TQCC of Biochimica et Biophysica Acta-Proteins and Proteomics is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Co-chaperonin GroES subunit exchange as dependent on time, pH, protein concentration, and urea	64
Structure prediction and engineering of de novo proteins	32
TMB Stab-pred: Predicting the stability of transmembrane β-barrel proteins using their sequence and structural signatures	30
Structure of the complex of camel peptidoglycan recognition protein-S with hexanoic acid reveals novel features of the versatile ligand-binding site at the dimeric interface	25
Solution-based studies on the contact between the complement receptor 3 ligand-binding domain and simvastatin	22
The regulation of the thermal stability and affinity of the HSPA5 (Grp78/BiP) by clients and nucleotides is modulated by domains coupling	20
CDR identification, epitope mapping and binding affinity determination of novel monoclonal antibodies generated against human apolipoprotein B-100	19
Deep learning-based method for predicting and classifying the binding affinity of protein-protein complexes	19
Active roles of lytic polysaccharide monooxygenases in human pathogenicity	18
Emerging roles of S100 proteins in podocyte biology and disease: A mini review	18
Understanding Huntingtin protein aggregation in cell mimicking environments	17
Chemical proteomics approaches for protein post-translational modification studies	15
Beta-KTx14.3, a scorpion toxin, blocks the human potassium channel KCNQ1	14
An intermolecular hydrogen bonded network in the PRELID-TRIAP protein family plays a role in lipid sensing	13
The oxidative nuclease activity of human cytochrome c with mutations in Ω-loop C/D	13
Identification of new protein-coding potential in Leishmania braziliensis using a proteogenomics approach	13
Structure and functional studies of Avt1, a novel peptide from the sea anemone Aulactinia veratra	12
AP lyase activity of the human ribosomal protein uS3: The DNA cleavage sequence specificity and the location of the enzyme active center	12
Direct cryo-EM visualization of the β-sheet structure in curved amyloid protofibril	11
Activity-guided identification, cloning, heterologous expression, and characterization of a highly thermostable mitochondrial superoxide dismutase from Lantana camara	10
Green tea polyphenol EGCG acts differentially on end-stage amyloid polymorphs of α-synuclein formed in different polyol osmolytes	10
Epitope mapping of SARS-CoV-2 RBDs by hydroxyl radical protein footprinting reveals the importance of including negative antibody controls	10
A single amino acid difference between archaeal and human type 2 methionine aminopeptidases differentiates their affinity towards ovalicin	10
Bacteriophage-encoded chaperonins stimulate prion protein fibrillation in an ATP-dependent manner	9
Elucidation of multifunctionality and substrate specificity of human aspartate aminotransferases	9

Biochemical and kinetic properties of quinone oxidoreductase from Leishmania orientalis, a member of medium-chain dehydrogenase/reductase superfamily	9
Editorial Board	9
Flexibility in acidophilic thioredoxins: Insights from Asp43 substitutions in E. coli thioredoxin	9
Uncovering the membrane-integrated SecAN protein that plays a key role in translocating nascent outer membrane proteins	9
Structural-functional relevance of DNAJBs in protein aggregation and associated neurodegenerative diseases	8
Aqueous BSA-PEG solutions under repeated temperature cycles: Liquid-liquid phase separation and properties of the dispersed and condensed phases	8
Exploring human carboxylesterases 1 and 2 selectivity of two families of substrates at an atomistic level	8
Structure-guided engineering of serratiopeptidase using constant-pH molecular dynamics and site-directed mutagenesis to improve pH-dependent functional resilience	8
Corrigendum to ‘Glycoproteomic characterization of Neuropilin-1 reveals critical glycosylation sites for SARS-CoV-2 entry’ [Biochimica et Biophysica Acta (BBA) - proteins and proteomics 1873 (5) (2025	8
Identification of peptides interfering with the PP2Ac And LRRK2 interaction	8
Plumbagin accelerates serum albumin's amyloid aggregation kinetics and generates fibril polymorphism by inducing non-native β-sheet structures	8
Importance of aspartate 4 in the Mg2+ dependent regulation of Leishmania major PAS domain-containing phosphoglycerate kinase	8
Citrus flavanone metabolites significantly modulate global proteomic profile in pancreatic β-cells under high-glucose-induced metabolic stress	7
Editorial Board	7
Aromatic interactions surrounding the Asp–X–Glu motif stabilize the active site of HYAL1 and PH20	7
Distinct dynamical features of plasmodial and human HSP70-HSP110 highlight the divergence in their chaperone-assisted protein folding	7
Disulfide-mediated dimerization stabilizes pyruvate kinase of Cryptosporidium parvum: Insights into unique structural assembly and functional implications	7
Evolution in neuropsychiatric cis-regulatory enhancers through human-specific neuronal mutations within transcription factor binding sites	6
Unravelling the phosphoregulatory network of protein kinase C-delta (PKC-δ)	6
Exploring liquid-liquid phase separation in the organisation of Golgi matrix proteins	6
The molecular basis of the antidepressant action of the magic mushroom extract, psilocin	6
FunPredCATH: An ensemble method for predicting protein function using CATH	6
Investigating protein aggregation in protein-carbohydrate interfaces using sequence and structural features	6
Propagation of conformational instability in FK506-binding protein FKBP12	5
The effect of pH and nitrite on the haem pocket of GLB-33, a globin-coupled neuronal transmembrane receptor of Caenorhabditis elegans	5
MS analysis of proteins concentrated on the surface of AFM chips from the blood plasma of healthy volunteers	5
Chemometric evaluation of key residues affecting the stability of cold shock proteins	5
Oxygen-carrying proteins employed in blood substitute candidates: differences in interactions with a model antioxidant molecule	5
FeoC from Klebsiella pneumoniae uses its iron sulfur cluster to regulate the GTPase activity of the ferrous iron channel	5
Biophysical characterization of Hpa1 protein from Xanthomonas orzyae	5
Substitution of carbonate by non-physiological synergistic anion modulates the stability and iron release kinetics of serum transferrin	5
Editorial Board	5
The structural basis of conserved residue variant effect on enzyme activity of UGT2B15	4
Role of electrostatics in cold adaptation: A comparative study of eury- and stenopsychrophilic triose phosphate isomerase	4
Understanding LexA as a central regulator of the bacterial SOS response	4
Editorial Board	4
The effect of denaturants on protein thermal stability analyzed through a theoretical model considering multiple binding sites	4
Proteomic profiling of valproic acid-treated zebrafish embryos highlights dysregulation in energy and purine metabolism, and microtubule dynamics: Implications for autism spectrum disorder	4
Corrigendum to “Mass spectrometry analysis of the oxidation states of the pro oncogenic protein anterior gradient-2 reveals covalent dimerization via an intermolecular disulphide bond” [Biochimica et	4
Editorial Board	4
The apo-acyl coenzyme A binding protein of Leishmania major forms a unique ‘AXXA’ motif mediated dimer	4
Elucidating the inhibitory effects of rationally designed novel hexapeptide against hen egg white lysozyme fibrillation at acidic and physiological pH	4
Human apo-metallothionein 1a is not a random coil: Evidence from guanidinium chloride, high temperature, and acidic pH unfolding studies	4
Structural basis of nuclear transport for NEIL DNA glycosylases mediated by importin-alpha	4
Structure of the Borrelia burgdorferi ATP-dependent metalloprotease FtsH in its functionally relevant hexameric form	4
Phafin2 modulates the aggregation of NLRP3 on dispersed trans-Golgi network	4
Molecular insights into diosgenin's role in preventing protein aggregation in neurodegenerative diseases	4
Strategy for probing the functionality and stereoselectivity of enzyme active sites: Single sites, multiple sites versus multiple molecular forms, conformations, allozymes and isozymes	4
Drug–biomolecular interaction: Spectroscopic and computational insights into esomeprazole binding with human serum albumin	4
Development of β-sheet structure in Aβ aggregation intermediates diminishes exposed hydrophobic surface area and enhances proinflammatory activity	4