Biochimica et Biophysica Acta-Proteins and Proteomics

Article	Citations
Cathepsin B in neurodegeneration of Alzheimer's disease, traumatic brain injury, and related brain disorders	88
The aging lysosome: An essential catalyst for late-onset neurodegenerative diseases	72
Challenge to overcome current limitations of cell-penetrating peptides	67
Determining protein–protein functional associations by functional rules based on gene ontology and KEGG pathway	56
Fungal Lanosterol 14α-demethylase: A target for next-generation antifungal design	56
Nitroxide spin labels and EPR spectroscopy: A powerful association for protein dynamics studies	47
Insights into predicting diabetic nephropathy using urinary biomarkers	42
A comprehensive study of construction and analysis of competitive endogenous RNA networks in lung adenocarcinoma	39
Structural and mechanistic insights into the Keap1-Nrf2 system as a route to drug discovery	37
Molecular recognition of fibroblast activation protein for diagnostic and therapeutic applications	37
Molecular and cellular dynamics of the 26S proteasome	31
Falcipain cysteine proteases of malaria parasites: An update	31
Cathepsin regulation on microglial function	30
Nucleophosmin, a multifunctional nucleolar organizer with a role in DNA repair	30
Production, thermodynamic characterization, and fruit juice quality improvement characteristics of an Exo-polygalacturonase from Penicillium janczewskii	30
Characterization of soluble folate receptors (folate binding proteins) in humans. Biological roles and clinical potentials in infection and malignancy	29
Analysis and prediction of protein stability based on interaction network, gene ontology, and KEGG pathway enrichment scores	28
Low barrier hydrogen bonds in protein structure and function	27
d-Alanine: Distribution, origin, physiological relevance, and implications in disease	27
Review and comparative analysis of machine learning-based phage virion protein identification methods	24
Understanding molecular enzymology of porphyrin-binding α + β barrel proteins - One fold, multiple functions	23
Calpains for dummies: What you need to know about the calpain family	22
Deficit of human ornithine aminotransferase in gyrate atrophy: Molecular, cellular, and clinical aspects	22
d-serine in physiological and pathological brain aging	21
Meta-omics analysis indicates the saliva microbiome and its proteins associated with the prognosis of oral cancer patients	21

Coumarin as a structural component of substrates and probes for serine and cysteine proteases	21
Combinatorial degradomics: Precision tools to unveil proteolytic processes in biological systems	20
Cysteinyl cathepsins in cardiovascular diseases	20
Proteomic advances in salivary diagnostics	19
Dysfunctional d-aspartate metabolism in BTBR mouse model of idiopathic autism	19
Cerebrospinal fluid and serum d-serine concentrations are unaltered across the whole clinical spectrum of Alzheimer's disease	18
Light spectra affect the in vitro shoot development of Cedrela fissilis Vell. (Meliaceae) by changing the protein profile and polyamine contents	17
Deep learning based prediction of species-specific protein S-glutathionylation sites	17
Advancing d-amino acid-containing peptide discovery in the metazoan	17
Update on relevant trypanosome peptidases: Validated targets and future challenges	16
Solid-state vibrational circular dichroism studies on the conformation of an amino acid molecule in crystalline state	15
New insights on the influence of free d-aspartate metabolism in the mammalian brain during prenatal and postnatal life	15
A unifying framework for amyloid-mediated membrane damage: The lipid-chaperone hypothesis	15
Proteomics in thyroid cancer and other thyroid-related diseases: A review of the literature	14
Inhibition of matrix metalloproteinase expression and cellular invasion by NF-κB inhibitors of microbial origin	14
A pilot study indicating the dysregulation of the complement and coagulation cascades in treated schizophrenia and bipolar disorder patients	13
Mass spectrometry-based proteomics analyses of post-translational modifications and proteoforms in human pituitary adenomas	13
Genetic analysis of Hsp70 phosphorylation sites reveals a role in Candida albicans cell and colony morphogenesis	13
Recent technological developments for native mass spectrometry	13
Utility of d-serine monitoring in kidney disease	12
Mechanisms of DNA−protein cross-link formation and repair	12
Targeted inhibition of amyloidogenesis using a non-toxic, serum stable strategically designed cyclic peptide with therapeutic implications	12
Single-cell proteomics: A treasure trove in neurobiology	12
Molecular simulations of proteins: From simplified physical interactions to complex biological phenomena	11
ESAT-6 regulates autophagous response through SOD-2 and as a result induces intracellular survival of Mycobacterium bovis BCG	11
Ceruloplasmin and oxidative stress in severe eosinophilic asthma patients treated with Mepolizumab and Benralizumab	11
Tumor cell- and microenvironment-specific roles of cysteine cathepsins in mouse models of human cancers	11
Predicting protein subcellular location with network embedding and enrichment features	11
Tyr-nitration in maize CDKA;1 results in lower affinity for ATP binding	10
Functional characterization of the different oligomeric forms of human surfactant protein SP-D	10
OMA1—An integral membrane protease?	10
A muscle-specific calpain, CAPN3, forms a homotrimer	10
Cone snail analogs of the pituitary hormones oxytocin/vasopressin and their carrier protein neurophysin. Proteomic and transcriptomic identification of conopressins and conophysins	10
Stage-specific protein regulation during somatic embryo development of Carica papaya L. ‘Golden’	10
Asp isomerization increases aggregation of α-crystallin and decreases its chaperone activity in human lens of various ages	10
Separation of D-amino acid-containing peptide phenylseptin using 3,3′-phenyl-1,1′-binaphthyl-18-crown-6-ether columns	10
Pathological cardiac remodeling seen by the eyes of proteomics	10
Application of mass spectrometry based proteomics to understand diabetes: A special focus on interactomics	10
Ubiquitin ligase Cbl-b and inhibitory Cblin peptides	9
Conformational analysis of the riboflavin-responsive ETF:QO-p.Pro456Leu variant associated with mild multiple acyl-CoA dehydrogenase deficiency	9
Post-translational modifications contribute to neoepitopes in Type-1 diabetes: Challenges for inducing antigen-specific tolerance	9
Silybins inhibit human IAPP amyloid growth and toxicity through stereospecific interactions	9
Effect of active-site aromatic residues Tyr or Phe on activity and stability of glucose 6-phosphate dehydrogenase from psychrophilic Arctic bacterium Sphingomonas sp.	9
Human cathepsin X/Z is a biologically active homodimer	9
Understanding enzyme behavior in a crowded scenario through modulation in activity, conformation and dynamics	9
Recent advances in proteomics and its implications in pituitary endocrine disorders	9
Characterization of large intact protein ions by mass spectrometry: What directions should we follow?	9
AbsoluRATE: An in-silico method to predict the aggregation kinetics of native proteins	8
Crystallographic investigation of the ubiquinone binding site of respiratory Complex II and its inhibitors	8
Analysis of Hashimoto's thyroiditis on fine needle aspiration samples by MALDI-Imaging	8

Target enzymes are stabilized by AfrLEA6 and a gain of α-helix coincides with protection by a group 3 LEA protein during incremental drying	8
Decipher the connections between proteins and phenotypes	8
Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding	8
Standard Gibbs energy of metabolic reactions: V. Enolase reaction	8
High-resolution structure of intramolecularly proteolyzed human mucin-1 SEA domain	8
Structural, thermodynamic and functional studies of human 71 kDa heat shock cognate protein (HSPA8/hHsc70)	7
Prediction of membrane protein types by fusing protein-protein interaction and protein sequence information	7
Loss of a water-mediated network results in reduced agonist affinity in a β2-adrenergic receptor clinical variant	7
The GLP-1 analog exendin-4 modulates HSP72 expression and ERK1/2 activity in BTC6 mouse pancreatic cells	7
HSPB1 influences mitochondrial respiration in ER-stressed beta cells	7
Native mass spectrometry for the investigation of protein structural (dis)order	7
Current status and future prospects for ion-mobility mass spectrometry in the biopharmaceutical industry	7
Dual effect of 2D WS2 nanoparticles on the lysozyme conformation	7
Enzymatic properties and physiological function of glutamate racemase from Thermus thermophilus	7
Nucleotide-dependent dynamics of the Dengue NS3 helicase	7
Crystal structure of a chitinase (RmChiA) from the thermophilic fungus Rhizomucor miehei with a real active site tunnel	7
N-succinylamino acid racemases: Enzymatic properties and biotechnological applications	7
Structural foundations of sticholysin functionality	7
Quantitative proteomics and phosphoproteomics of Trypanosoma cruzi epimastigote cell cycle	6
The structure of a prokaryotic feruloyl-CoA hydratase-lyase from a lignin-degrading consortium with high oligomerization stability under extreme pHs	6
Isobenzofuran-1(3H)-ones as new tyrosinase inhibitors: Biological activity and interaction studies by molecular docking and NMR	6
Modulation of α-synuclein phase separation by biomolecules	6
Phosphopantetheine Adenylyltransferase: A promising drug target to combat antibiotic resistance	6
Immune response pattern across the asymptomatic, symptomatic and convalescent periods of COVID-19	6
Protein oxidation marker, α-amino adipic acid, impairs proteome of differentiated human enterocytes: Underlying toxicological mechanisms	6
Hydroxyl radical footprinting analysis of a human haptoglobin-hemoglobin complex	6
The nuclear localization sequence of the epigenetic factor RYBP binds to human importin α3	6
In silico analysis of the aggregation propensity of the SARS-CoV-2 proteome: Insight into possible cellular pathologies	6
Amyloid fibril formation by αS1- and β-casein implies that fibril formation is a general property of casein proteins	6
Apolipoprotein E4 exhibits intermediates with domain interaction	6
Regulation of Herbaspirillum seropedicae NifA by the GlnK PII signal transduction protein is mediated by effectors binding to allosteric sites	6
Heterotypic signaling between dermal fibroblasts and melanoma cells induces phenotypic plasticity and proteome rearrangement in malignant cells	6
Quantitative profiling of axonal guidance proteins during the differentiation of human neurospheres	6
Biochemical characterization of mouse d-aspartate oxidase	5
Functional and structural characterization of an α-ʟ-arabinofuranosidase from Thermothielavioides terrestris and its exquisite domain-swapped β-propeller fold crystal packing	5
Molecular trait of follicular-patterned thyroid neoplasms defined by MALDI-imaging	5
Intrinsic affinity of protein – ligand binding by differential scanning calorimetry	5
Structurally plastic NEMO and oligomerization prone IKK2 subunits define the behavior of human IKK2:NEMO complexes in solution	5
Crystal structure and physicochemical characterization of a phytocystatin from Humulus lupulus: Insights into its domain-swapped dimer	5
Mapping human calreticulin regions important for structural stability	5
A crucial residue in the hydrophobic core of the solenoid structure of leucine rich repeats	5
Targeting protein tyrosine phosphatases for the development of antivirulence agents: Yersinia spp. and Mycobacterium tuberculosis as prototypes	5
AP sites in various mRNA positions cross-link to the protein uS3 in the translating mammalian ribosome	5
Computational studies on nonenzymatic succinimide-formation mechanisms of the aspartic acid residues catalyzed by two water molecules	5
The impact of blood-processing time on the proteome of human peripheral blood mononuclear cells	5
Structural mass spectrometry of membrane proteins	5
Analysis of uracil DNA glycosylase (UNG2) stimulation by replication protein A (RPA) at ssDNA-dsDNA junctions	5
Criticality in the conformational phase transition among self-similar groups in intrinsically disordered proteins: Probed by salt-bridge dynamics	5
Analysis of ovarian cancer cell secretome during epithelial to mesenchymal transition reveals a protein signature associated with advanced stages of ovarian tumors	5
Impaired nuclear transport induced by juvenile ALS causing P525L mutation in NLS domain of FUS: A molecular mechanistic study	5
Determination of phenylalanine enantiomers in the plasma and urine of mammals and ᴅ-amino acid oxidase deficient rodents using two-dimensional high-performance liquid chromatography	5
Proteomic insights into protostane triterpene biosynthesis regulatory mechanism after MeJA treatment in Alisma orientale (Sam.) Juz.	4
Tetramer protein complex interface residue pairs prediction with LSTM combined with graph representations	4
The explorations of dynamic interactions of paxillin at the focal adhesions	4
Steady-state kinetic analysis of human cholinesterases over wide concentration ranges of competing substrates	4
Towards low false discovery rate estimation for protein-protein interactions detected by chemical cross-linking	4
Changes in strand 6B and helix B during neuroserpin inhibition: Implication in severity of clinical phenotype	4
The NADP-dependent malic enzyme MaeB is a central metabolic hub controlled by the acetyl-CoA to CoASH ratio	4
Genetic variants entail type 2 diabetes as an innate immune disorder	4
Revisiting the stem proteome of Eucalyptus grandis and Eucalyptus globulus: Identification of temperature-induced changes	4
The DEAD-box RNA helicase eIF4A1 interacts with the SWI2/SNF2-related chromatin remodelling ATPase DDM1 in the moss Physcomitrella	4
Determination of terminal glycan and total monosaccharide profiles of reelin glycoprotein in SH-SY5Y neuroblastoma cell line by lectin blotting and capillary liquid chromatography electrospray ionizat	4
SopD from Salmonella specifically inactivates Rab8	4
Physicochemical and structural properties of lunasin revealed by spectroscopic, chromatographic and molecular dynamics approaches	4
d-Aspartate N-methyltransferase catalyzes biosynthesis of N-methyl-d-aspartate (NMDA), a well-known selective agonist of the NMDA receptor, in mice	4
Enzymatic properties of Myxococcus xanthus exopolyphosphatases mxPpx1 and mxPpx2	4
Arg236 in human chymotrypsin B2 (CTRB2) is a key determinant of high enzyme activity, trypsinogen degradation capacity, and protection against pancreatitis	4
The extended N-terminus of Mycobacterium smegmatis RecX potentiates its ability to antagonize RecA functions	4
Structures and mechanisms of formation of liprotides	4
Designer D-peptides targeting the N-terminal region of α-synuclein to prevent parkinsonian-associated fibrilization and cytotoxicity	4
Dissecting the structural features of β-arrestins as multifunctional proteins	4
Polyol and sugar osmolytes stabilize the molten globule state of α-lactalbumin and inhibit amyloid fibril formation	4
Computational prediction and analysis of histone H3k27me1-associated miRNAs	4
Design and Applications of Bifunctional Small Molecules in Biology	4
Seryl-tRNA synthetase specificity for tRNASec in Bacterial Sec biosynthesis	4
High-resolution structure of a modular hyperthermostable endo-β-1,4-mannanase from Thermotoga petrophila: The ancillary immunoglobulin-like module is a thermostabilizing domain	4
Selective pressure on an interfacial enzyme: Functional roles of a highly conserved asparagine residue in a cellulase	3
Detection of key sites of dimer dissociation and unfolding initiation during activation of acid-stress chaperone HdeA at low pH	3
Age-related isomerization of Asp in human immunoglobulin G kappa chain	3
Mechanism of eukaryotic serine racemase-catalyzed serine dehydration	3

Aggregation kinetics of the protein photoreceptor Vivid	3
Probing the role of Val228 on the catalytic activity of Scytalidium catalase	3
Tyrosine-sulfated dermatopontin shares multiple binding sites and recognition determinants on triple-helical collagens with proteins implicated in cell adhesion and collagen folding, fibrillogenesis,	3
Modulation of the carbohydrate-binding specificity of two Xenopus proto-type galectins by site-directed mutagenesis	3
Human serine racemase is inhibited by glyceraldehyde 3-phosphate, but not by glyceraldehyde 3-phosphate dehydrogenase	3
Metaviromics analysis of marine biofilm reveals a glycoside hydrolase endolysin with high specificity towards Acinetobacter baumannii	3
Identification of novel protein-coding sequences in Eucalyptus grandis plants by high-resolution mass spectrometry	3
The armadillo-repeat domain of Plakophilin 1 binds to human enzyme PADI4	3
Fast photochemical oxidation of proteins coupled with mass spectrometry	3
A conserved π-helix plays a key role in thermoadaptation of catalysis in the glycoside hydrolase family 4	3
Characterization of an NAD(P)+-dependent meso-diaminopimelate dehydrogenase from Thermosyntropha lipolytica	3
Citrus flavanone metabolites significantly modulate global proteomic profile in pancreatic β-cells under high-glucose-induced metabolic stress	3
Gamma cleavage is a rate-determining step in the gamma-elimination reaction of L-methionine analogues catalyzed by methionine-gamma-lyase	3
TGFβ1-Smad3 signaling mediates the formation of a stable serine racemase dimer in microglia.	3
An assay procedure to investigate the transformation of toxic heme into inert hemozoin via plasmodial heme detoxification protein	3
Phosphoproteomic response of cardiac endothelial cells to ischemia and ultrasound	3
The alpha helix of the intermediate region in hGBP-1 acts as a coupler for enhanced GMP formation	3
Characterization of E121K mutation of D-amino acid oxidase – Insights into mechanisms leading to amyotrophic lateral sclerosis	3
New insights into short peptides derived from the collagen NC1 α1, α2, and α3 (IV) domains: An experimental and MD simulations study	3
Regulation of the α-ketoglutarate dehydrogenasecomplex during hibernation in a small mammal, the Richardson's ground squirrel (Urocitellus richardsonii)	3
The Fe and Zn cofactor dilemma	3
His180 in the pore-lining α4 of the Bacillus thuringiensis Cry4Aa δ-endotoxin is crucial for structural arrangements of the α4-α5 transmembrane hairpin and hence biotoxicity	3
Proteomic changes in Trypanosoma cruzi epimastigotes treated with the proapoptotic compound PAC-1	3
Effect of tubulin self-association on GTP hydrolysis and nucleotide exchange reactions	3