Letters in Drug Design & Discovery

Article	Citations
Acknowledgements to Reviewers	161
Preparation of Levothyroxine Transdermal Gels and Preliminary Pharmacokinetic Study in Hypothyroidism Rat Model	82
Piperazine-based Semicarbazone Derivatives as Potent Urease Inhibitors: Design, Synthesis, and Bioactivity Screening	37
Exploring Novel PLK1 Inhibitors based on Computational Studies of 2,4-Diarylaminopyrimidine Derivatives	33
Repurposing Novel Antagonists for Targeting p7 Viroporin of HCV Using In Silico Approach	30
Synthesis and Anticancer Activity of Oral Pt(IV) Prodrugs Containing α-furancarboxylate as an Axial Ligand	29
Molecular Docking, Molecular Dynamics Simulation, and Analysis of EGFR-derived Peptides against the EGF	28
Innovative approaches in insulin delivery: Exploring molecular techniques and system developments	27
Ligand-based Pharmacophore Modeling, Molecular Docking and Simulation Studies for the Exploration of Natural Potent Antiangiogenic Inhibitors Targeting Heat Shock Protein 90	27
Discovery of Structural Prospects of Imidazo[1,5-a]pyrazine Derivatives as BTK Inhibitors Against Cancer: A Computational Study	26
Recent Developments, Challenges and Opportunities in Targeting the KRAS Pathway	24
Synthesis, Molecular Docking Studies, and In vitro Anticancer Evaluation of Novel Tolfenamic Acid Derivatives	23
Plant Secondary Metabolites as Apoptosis-inducing Agents	22
Synthesis, Characterization, and Evaluation of Sulfonium Lipids as Potential Nonviral Gene Vectors	19
Computational Insights on Migraine and Anxiety in Association with BDNF	18
Computational Study of Lactucine and its Derivatives to Investigate its Anti-cancerous Properties Targeting Apoptosis-inducing Protein	15
Positive Expression of Paired Box 5 (Pax5) was Associated with Age, Tumor Location, and Tumor Size of Patients with Gastrointestinal Neuroendocrine Tumors (NETs)	15
Screening and Structure-Activity Relationship of Potential Compounds against Proposed Targets of COVID-19 Infection	15
Mechanistic Investigation of Glycyrrhiza uralensis Effects against Respiratory Ailments: Application of Network Pharmacology and Molecular Docking Approaches	14
Anti-cancerous Properties of the Synthesized Substituted Chromene Compounds and their Pharmacological Activities	14
Synergy Potential of Ursolic Acid-Based Hybrid Molecules	14
Design, Synthesis and In Vitro Anticancer Activity of Benzo[c]chromen-6- one-linked 1,2,3-Triazole	12
Regulation of Exosomes-Mediated circNR4A1 on Chemoresistance and Biological Effects of Oral Squamous Cell Carcinoma Cells	12
From stem cells to therapeutics: Advancing islet function restoration through mesenchymal stem cell-based drug research	11
A Review on Synthesis and Biological Potential of Dihydropyridines	11

Synthesis and Antimicrobial Activity of Functional Derivatives of thiazolo[ 2,3-c][1,2,4]triazoles	11
Potent Small Molecules Inhibitors Discovery through Ligand-based Modelling for Effective Treatment of Parkinson’s Disease	11
Ligand-based Molecular Modeling of HDL Receptor SR-BI Inhibitors as Potent Anti-hyperlipidemic Agents	10
Unifying Theory and Experiments: Multi-Target Pharmacology of Dajihan Pill Against Hyperlipidemia	10
Modified Release of Acetaminophen from Matrix Tablet Formulations: Influence of Tablet Geometry	10
Synthetic PARP-1 Inhibitors Reported During the Last Decade	10
The Essential Role of Herbal-based Therapies in Combatting Acne Vulgaris	10
The search for the holy grail: In silico design and analysis of a non-sedative third generation, cetirizine-derived H1R anti-histamine with reduced hERG toxicity	10
Study on the Mechanism of Sanqi in the Treatment of Disseminated Intravascular Coagulation-Based on Network Pharmacology and Molecular Docking Technology	10
Evaluation of the Impact of Pistacia atlantica Desf. Oleo-gum Resin on Complete Freund’s Adjuvant-induced Arthritis in a Wistar Rat Model	10
Evolutionary History of Oncogenes and Tumor Suppressor Genes Families: The Ancestral Origin in Mammals and Duplication Patterns	9
The Role of Aquatic Plants in Natural Products and Drug Discovery	9
QSAR of SARS-CoV-2 Main Protease Inhibitors Utilizing Theoretical Molecular Descriptors	9
Restraint of Starch-hydrolyzing Enzyme in the Management of Postprandial Blood Glucose Level: An Alternative Approach	9
Antimicrobial Activity of Halogen- and Chalcogen-Functionalized Thiazoloquinazolines	9
Implementation of PLGA-based Nanoparticles for Treatment of Colorectal Cancer	8
The effect of serotonergic receptors (5HT3) on seizure threshold and mitochondrial damage induced by amitriptyline in the mouse brain	8
A Network Pharmacology Guided Mechanism of Action Study on Oldenlandia diffusa Against Osteosarcoma	8
Triptolide and quercetin coordinately regulate the network pharmacology mechanism of renal cancer	8
Effect and safety of modified-release insulin-loaded liposome prototypes on glycemia in experimental models of type 1 diabetes mellitus	8
Anti-Tumor Activity of Indole: A Review	8
Anti-colorectal Cancer Activity of Quinazoline Derivatives: A Comprehensive Review	8
Phytochemical Characterization and Screening of the Anti-Pneumonia (Anti-COVID-19, Anti-Fungal, and Anti-Bacterial) Activities of Cuscuta Campestris Extract	8
A Comprehensive Review of the Advancement in Omic Technologies in the Field of Drug Discovery and Development	7
Formulation Development and Assessment of Solid Dispersion and Hydrotropy for BCS Class II Drug Solubility Enhancement	7
Insight View on the Pharmacological Potential and Bio-active Components of Ginger	7
The Newly Proposed Mechanism of Cardiomyocyte Protection of Carvedilol- Anti-Apoptosis Pattern of Carvedilol in Anoxia by Inducing Autophagy Partly through the AMPK/mTOR Pathway	7
WITHDRAWN: Synthesis and Anticancer Activity of Newly Substituted 1,3,4-thiadiazole Derivatives: A Novel Class of Anticancer Agents	7
Design of VEGFR2 Inhibitors: Construction and Screening of Virtual Compound Libraries	7
The Effects of Trigonella Foenum-graecum L. on Post-surgical Adhesion Band Formation	7
A Comparative Computational Analysis Approach to Predict Significant Protein-Protein Interactions of Human and Vancomycin Resistant Enterococcus faecalis (VRE) to Prioritize Potential Drug Targets	7
Advances in Isatin-derived Compounds for Modern Cancer Therapy: A Comprehensive Review	7
Synthesis and Studies of Anticancer and Antimicrobial Activity of New Phenylurenyl Chalcone Derivatives	6
Baicalein Promotes Acute Myeloid Leukemia Cell Autophagy via miR-424 and the PTEN/PI3K/AKT/mTOR Pathway	6
WITHDRAWN: The Radix Achyranthes Bidentata Regulates BMSCsderived Chondrogenic Differentiation by Modulating Rab39a and Activating SOX9 and RHOA/RACK1 Signaling	6
Discovery of Natural Compounds as SARS-CoV-2’s Main Protease Inhibitors by Docking-based Virtual Screening	6
Identifying TMPRSS2 Inhibitors by Drug Repurposing Screenings of Known fXIa Inhibitors: A Computational Study	6
Docking Study on Caspase 3 Inhibitors As Potential Drugs For Traumatic Brain Cell Apoptosis	6
Exploring Nature’s Treasure for Drug Discovery	6
Antimicrobial Activities of Substituted 4-N-alkylated-2-trifluoromethylquinoline Analogs Against Nontuberculous Mycobacteria	6
Advanced Oral Drug Delivery Systems for Combating and Preventing Paediatric Periodontal Disease	6
Association of SARS-CoV-2 Infection and Triple Negative Breast Cancer (TNBC) A Computational Illustrative Study	6
Physically Crosslinked Polymeric Network for Controlled and Mucoadhesive Release of Miconazole for Topical Ocular Delivery	6
WITHDRAWN: Iodinated Curcumin as a Novel Anti-bacterial Agent to Combat Methicillin-resistant Staphylococcus aureus in Bovine Mastitis: In Silico Analysis, Synthesis and In Vitro Evaluation	6
Synthesis and Pharmacological Activity of 4', 4''- bit Modified Curcumin Derivatives	6
A Scoping Review on Recent Progress on Purpurin and its Derivatives	6
Analysis of Ultrasound Supported Antimicrobial and Antibiofilm Activities of Disinfection By-product Bromochloroacetonitrile	6
Saponins-uptake and Targeting Issues for Brain-specific Delivery for Enhanced Cell Death Induction in Glioblastoma	6
Molecular Docking: Principles, Advances, and Its Applications in Drug Discovery	6
The Inhibitory Effect and Mechanism of Action of Myricaria germanica Essential Oils on Skin Inflammation based on Network Pharmacology and Molecular Docking	6

Neuroprotective and Nootropic Evaluation of some Important Medicinal Plants in Dementia: A Review	6
Whole-cell Lipase Catalytic Synthesis of Short-chain Fragrance Esters using Aspergillus flavus	6
Recent Advances in Drug Design and Delivery Across Biological Barriers Using Computational Models	6
Exploring the Potential of Avenanthramides and their Analogues as α-Glucosidase Inhibitors for Type 2 Diabetes Treatment Utilizing Virtual Screening, Molecular Dynamics, and Drug-likeness Predictions	6
Design, Synthesis, and In vitro Biological Activities of Matrine Skeleton Derivatives as Potential Cancer Inhibitors	6
QSAR Analysis and Molecular Docking Studies of Aryl Sulfonamide Derivatives as Mcl-1 Inhibitors and the Influence of Structure and Chirality on the Inhibitory Activity	5
Design, Synthesis, and Assay of New N-acyl-4-(4-aminoalkoxy- phenyl)- thiazole-2-amine Derivatives as Acetylcholinesterase Inhibitors	5
Up-to-date Combinational Polymeric Approaches for the Enhancement of Drug Absorption and Membrane Transductivity	5
Mechanism of Trigonella Foenum-graecum L. against Type 2 Diabetes Mellitus: Research on Network Pharmacology & Experimental Verification	5
Essential Structural Profile of Novel Adenosine Derivatives as Antiplatelet Aggregation Inhibitors based on 3D-QSAR Analysis	5
Development and evaluation of optimized molecularly imprinted polymer (MIP) for targeted drug delivery of 5-Fluorouracil	5
Design, Synthesis, and In vitro Anticancer Activity of Novel Chrysin Derivatives	5
Mitigation of cyclophosphamide-induced hepatoxicity by Allium ampeloprasum Subsp Iranicum: A potential protective agent in chemotherapy	5
Nitrogen-containing Heterocyclic Derivatives of 1,3-Thiazolidine-2,4- Diones as Dual Anti-inflammatory and Anti-oxidant Agents and their Docking Studies	5
Exploring DPP-IV inhibitors for diabetes treatment: A comprehensive study on molecular docking, molecular dynamics simulation, and in-vitro DPP-IV assay	5
A Review on Biological Activity of Quinoline-based Hybrids	5
“Thiophene”: A Sulphur Containing Heterocycle as a Privileged Scaffold	5
Morelloflavone as Potential Anticancer Agent Against MCF-7 Breast Cancer Cell Lines: In vitro and In silico Studies	5
Graviola Protects Against Hepatic Toxicity Associated with DMBA induced Breast Cancer via Restoration of Antioxidants and Attenuation of Inflammatory Pathways	5
Molecular Docking, Acute Toxicity and Antibacterial Study of Debilon and Phorbasterone-B Extracted from Rhodophyta	5
Discovery of MAO-A Inhibitors as Antidepressant Based on Virtual Screening	5
The Therapeutic Potential of Metformin for Attenuating Postsurgical Adhesion Band Formation	5
Development and characterization of suppository formulation for rectal delivery of clarithromycin	5
Angiotensin-Converting Enzyme Inhibition Properties and Antioxidant Effects of Plants and their Bioactive Compounds as Cardioprotective Agent	5
Acknowledgements to Reviewers	5
Novel 1,3,4-trisubstituted Pyrazolopyrimidine Derivatives Show Potent Antiproliferative Activity in Mantle Cell Lymphoma	5
KBH4 assisted synthesis of ultra-large mesoporous silica nanosystem encapsulating paclitaxel and glucose oxidase for starvation/chemo-therapy	5
In vitro Cholinesterase Inhibitory Activities of Piper betle Stem and their Correlation with In silico Docking Studies of its Phytoconstituents	5
Rings in “Lead-like Drugs”	5
Design and Prediction of ADME/Tox Properties of Novel Magnolol Derivatives as Anticancer Agents for NSCLC Using 3D-QSAR, Molecular Docking, MOLCAD and MM-GBSA Studies	5
Identification of Novel Nrf2 Activator via Protein-ligand Interactions as Remedy for Oxidative Stress in Diabetes Mellitus	5
A comprehensive in-silico approach (pharmacophoric QSAR and docking-based comparative intermolecular analysis) led to identifying new PIM2 kinase inhibitors for treating resistant lymphomas	5
Design of Dual COX-2 and 5-LOX Inhibitors with Iron-Chelating Properties Using Structure-Based and Ligand-Based Methods	5
Exploring Novel Benzopyran Derivatives as Antitubercular Agents	5
Identification of active compounds and therapeutic mechanisms of traditional Chinese medicine for periarthritis of shoulder for promoting blood circulation and removing stasis (PBRS): A network pharma	5
Design, Synthesis, and Insecticidal Evaluation of New Benzoylureas Containing Carbamate Groups Based on the Bipartite Model of Sulfonylurea Receptor Binding Site	5
Molecular Docking of the Terpenes in Gorgonian Corals to COX-2 and iNOS Enzymes as Anti-Inflammatory	5
Bioinformatic Screening of Compounds from Iranian Lamiaceae Family Members against SARS-CoV-2 Spike Protein	5
In silico De Novo Discovery of Novel Target-specific Drug-like Bidentate Inhibitors of PTP 1B	4
Network pharmacology, molecular docking, and experimental validation of dihydromyricetin attenuating LPS-induced acute lung injury by promoting FGFR1	4
Potential of Surface Functionalized Nanomaterials in Innovative Drug Development: A Mini-review	4
Molecular Modeling of some 1,3,4-Oxadiazole Derivatives as EGFR Inhibitors for the Treatment of Cancer	4
Network Pharmacological Study of the Active Ingredient of Panax Notoginseng Saponins for the Treatment of Lung Cancer by Inhibiting AKR1C3	4
Towards Further Understanding the Role of Curcumin in Wound Healing: A Systems Biology Approach	4
Bdellovibrio bacteriovorus Therapy, an Emerging Alternative to Antibiotics	4
Quantum Mechanics Modeling of Oxetanes as Epoxide Hydrolase Substrates	4
Garcinol: An emerging epigenetic modifier with versatile anticancer properties	4
Synthesis and Biological Evaluation of Hydroxypropyl Ester of Mefenamic Acid as a Promising Prodrug	4
Efficacy and safety of PD-1/PD-L1 inhibitors for relapsed/metastatic nasopharyngeal carcinoma: A systematic review and meta-analysis	4
Conjugation of Mycophenolic Acid with Dextran: A Potential Strategy for Colon-Targeted Delivery for Mitigation of Inflamed Colon in Ulcerative Colitis	4
Polygenic Regulation by Flos Daturae in the Treatment of Breast Cancer: A Study based on Network Pharmacology and Bioinformatics	4
Novel 2-pyridone Analogs with Anti-cancer Activity: Synthesis, In silico, and In vitro Evaluation	4
Virtual Screening, Molecular Docking, and Physiochemical Analysis of Novel 1,3-diphenyl-2-propene-1-one as Dual COX-2/5-LOX Inhibitors	4
Rational Design and Synthesis of Novel Benzimidazole Derivatives as Potential β-Glucosidase Inhibitors	4
Nanotechnology-Based Approaches for Nose-to-Brain Drug Delivery in Neurodegenerative Diseases	4
The Contribution of the Rat Mesenteric Vascular Bed Model to Phytopharmacology with Computational Studies of the Main Vasorelaxant Phytochemicals	4
Synthesis, Characterization and Screening of Some Novel 2-Methyl-N'- [(Z)-Substituted-Phenyl ethylidene] Imidazo [1, 2-a] Pyridine-3-Carbohy drazide Derivatives as DPP-IV Inhibitors for the Treatment	4
Molecular Docking, Dynamics Simulation, and Physicochemical Analysis of Some Phytochemicals as Antiplatelet Agents	4
Lycopene-Loaded Solid Lipid Nanoparticles: Preparation, Characterization, ROS-Scavenging, and In vitro Anti-Melanogenesis Evaluations	4
Demonstration of Interaction between Carbapenem Group Antibiotics and Different Immunosuppressant Drugs by Molecular Docking	4
Pharmacophore Based Design of Probable FGFR-1 Inhibitors from the 3D Crystal Structure of Infigratinib - A Drug Used in the Treatment of Cholangiocarcinomas	4
Exploration of the mechanism of quercetin against GDM based on network pharmacology and molecular docking	3
Exploring the antimicrobial and biofilm inhibitory potential of Citrus limetta peel essential oil against multidrug-resistant Shigella: In vitro and in silico insights	3
A Review of the Azasteroid-type 5-alpha Reductase Inhibitors for the Management of Benign Prostatic Hyperplasia	3
Exploration of the potential molecular mechanism of magnolol in colorectal cancer treatment based on network pharmacology and molecular docking	3
One-Pot Green Synthesis of Novel Thiazolepyridine Conjugated Benzamides as Anti-Bacterial Agents and their Molecular Modelling Studies	3
Synthesis, Computational Study, and Anticonvulsant Activity of Newly Synthesized 2-aminobenzothiazole Derivatives	3
Synthesized Drug from Medicinal Plant phytochemicals Effectively Targets ECM1 Gene Mutations in Ulcerative Colitis	3
Structure-guided Development of Novel Benzothiophene Derivatives as PLK1-PBD Inhibitors	3
Effects of Compound in Hedyotis diffusa Willd against Acute Myeloid Leukemia: An In Silico and In Vitro Study	3
Mechanism of Pyroptosis in Postoperative Cognitive Dysfunction Rats and α7-nicotinic Receptor Agonist Regulating NLRP3 Inflammasome Activation	3
Preparation of Metformin Biodegradable Polymeric Microparticles by O/O Emulsion Solvent Evaporation: A 32 Full Factorial Design Approach	3
The Hepatoprotective Effect of a Newly Synthesized 5-mercapto-1,2,4-triazole Derivative based on Nalidixic Acid against CCl4 induced Oxidative Stress in Mice	3
Investigating the mechanism of curcumin against LUAD malignant progression and macrophage M2 polarization based on network pharmacology, bioinformatics, and molecular docking	3
Imperatorin remits malignant progression of endometrial cancer by silencing E2F1/SLC3A2	3
An Ultrasound-assisted Three Component Protocol for the Regio and Stereo-selective Synthesis of Some Novel Dispiroheterocycles and Their Biological Evaluation as Anti-inflammatory, Anti-obesity Agents	3
Identification of Potential Inhibitors for Severe Acute Respiratory Syndrome-related Coronavirus 2 (SARS-CoV-2) Angiotensin-converting Enzyme 2 and the Main Protease from Anatolian Traditional Plants	3
Natural Antioxidants of the Underutilized and Neglected Plant Species of Asia and South America	3
Exploring the Antitumor Potential of New Indazole-indolizines Designed by Molecular Hybridization	3
Recent Advances in Therapeutic Strategies against Hydatid Cysts using Nanomaterials: A Systematic Review	3

Perillaldehyde Building Block’s Derivatives: Targeted Bioactivities and Molecular Docking	3
In-silico Studies, Synthesis, and Evaluation of Anti-inflammatory Activity of Novel Pyrimidine Scaffold	3
Diversely Functionalized Pyridine Ring-fused Heterocycles and their Anticancer Properties	3
Palladium (II)-N-heterocyclic Carbene Complexes: Synthesis, Molecular Docking, UV-Vis Absorption and Enzyme Inhibition	3
Role of a Dual Inhibitor of RAS/PI3K/AKT and RAS/RAF/MEK on Post-surgical Adhesion Band Formation	3
Identification of Novel CDK 4/6 Inhibitors by High-throughput Virtual Screening	3
Computational Design of a Novel Inhibitor against COVID	3
Molecular Modelling Simulations and Inhibitory Effects of Naturally Derived Flavonoids Targeting Platelet-Activating Factor Receptor (PAFR)	3
Synthesis, Characterization, Antibacterial Evaluation, and Enzyme Inhibition Activity of a Novel Nitrogen-containing Heterocyclic Sulfonamide	3
Virtual Screening of Telaprevir and Danoprevir Derivatives for Hepatitis C Virus NS3/4A Protease Inhibitors	3
Assessment of Binding Site and Development of Small Molecule Inhibitors Targeting Epidermal Growth Factor Receptor Mutations in Non-Small Cell Lung Cancer (NSCLC)	3
Thymoquinone suppresses cell growth and induces ferroptosis in renal cell carcinoma by reducing SERPINH1 expression	3
Synthesis of Chromen-1-phenylpropan-1-one Derivatives and their Antidepressant/ Anticonvulsant Activities	3
Ethosomes: Novel Vesicular Carriers for Effective Transdermal Delivery of Natural Therapeutics	3
Exploring the mechanism of Grifolin in inhibiting the malignant progression of colon cancer cells mediated by the PDGFRB/PI3K/AKT signaling pathway based on bioinformatics analysis and network pharmac	3
Metformin Sensitizes Cisplatin-induced Apoptosis Through Regulating Nucleotide Excision Repair Pathway In Cisplatin-resistant Human Lung Cancer Cells	3
Phytosome: An Effective Transdermal Drug Delivery System for Phytoconstituents	3
CD44 as the Target Site for Hyaluronic Acid in Favor of Colitis Management	3
Molecular Docking Studies for Protein-Targeted Drug Development in SARS-CoV-2	3
The Importance of Salicylic Acid, Humic Acid and Fulvic Acid on Crop Production	3
The Synthesis and Pharmacological Activity of Ursolic Acid Derivatives Modified at C-28 and C-3 Sites	3
Based on the Network Pharmacology to Analyze the Effect of Chuanxiong in Improving Diabetic Nephropathy	3
Bioactive Natural Leads and Traditional Herbal Plants in the Management of Inflammatory Bowel Diseases: A Brief Review	3
Potential Drug Targets Identification Against Clostridioides Difficile (CD) and Characterization of Indispensable Proteins by a Subtractive Genomics Approach Followed by Virtual Screening	3
Synthesis, Characterization, and Evaluation of Antioxidant Activities of 2-(1-(Substituted phenyl)ethylidene)-1-(4,6-dimethylpyrimidin-2-yl)hydrazines	3
Design and Screening of KLHL22 Inhibitors by Homology Modeling, Molecular Docking, and Molecular Dynamics Simulation	3
Synthesis and Anti-proliferative, Tyrosine Kinases Inhibitions of New Xanthene Derivatives and their Morphological Studies	3
Multi-modal investigation of doxorubicin-induced osteoporosis: Network toxicology, machine learning, and imaging techniques	3
Synthesis and Biological Activity of 2-pyridone Derivatives: A Mini Review	3
Formulation and Characterization Studies of Paclitaxel Incorporated Kollidon® SR and Chitosan Nanoparticles: An In vitro Evaluation for Potential Use for Colorectal Cancer Treatment	3
A Novel Drug Delivery Platform Against Bacterial Resistance: Synthesis and Characterization of Ciprofloxacin-loaded MCM-41 Mesoporous Silica Nanoparticle	3
The effects of hydrogen-rich water on gut microbiota and related health outcomes: A systematic review	3
An appraisal on biomolecular imaging in diagnosis of neurological disorders and innovation in clinical research	3
Exploring the mechanism of action of tolvaptan in the treatment of cor pulmonale pulmonary hypertension using network pharmacology and animal-based experiments	3
Aptamers-based Strategies for the Treatment of Microbial Infections	2
Remifentanil and Propofol Co-loaded Nanoemulsion: Formulation Development and In vivo Pharmacodynamic Evaluation	2
Design, Synthesis, Biological Evaluation, Molecular Docking, and Molecular Dynamics Simulation Studies of Fmoc-L-Lysine Carboxamides as Promising Cytotoxic Agents	2
Molecular Dynamics Simulations and Binding Free Energy Calculations to Discover New Insights into NLRP3 Inhibitors	2
A Rational Approach to Anticancer Drug Design: 2D and 3D- QSAR, Molecular Docking and Prediction of ADME Properties using Silico Studies of Thymidine Phosphorylase Inhibitors	2
QSAR Studies on a Series of Pyrazole Azabicyclo [3.2.1] Octane Sulfonamides N-acylethanolamine-hydrolyzing Acid Amidase Inhibitors	2
Anti-evolution Drugs: A New Paradigm to Combat Drug Resistance	2
The Most Important Medicinal Herbs and Plants in Traditional Chinese and Iranian Medicinal Sciences with Antioxidant Activities	2
Shugan Jiangzhi Decoction Alleviates Nonalcoholic Fatty Liver Disease (NAFLD) via Regulating AMPK/PPAR Signaling Pathway	2
Asiaticoside Enhances the Osteoblast Potential of LPS-induced Periodontal Ligament Stem Cells through TLR4/NF-κB Pathway	2
Molecular Simulation Studies of Alpha Pinene, an Alkene in Search for Oxidative Stress Targeted Therapeutic Paradigms for the Treatment of Parkinson’s Disease: A Computational Approach and Its In-Vitr	2
Coronavirus Inhibitory Activity of Tamarind Indica	2
QSAR Model Study of 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole of Cystic- brosis-transmembrane Conductance-regulator Gene Potentiators	2
In silico Investigation of Identified Major Metabolites from Coffea Arabica Leaves against Parkinson’s Disease Target Proteins for Neuroprotective Drug Development	2
Ginsenoside Rh3 suppresses cell proliferation, metastasis, and oxidative stress of colorectal cancer via targeting HSP90AA1	2
Gm15886-Hipk1 Signaling Pathway Plays Important Roles in the Pathogenesis of Bronchopulmonary Dysplasia Mice	2
A Linear and Nonlinear QSAR Analysis of Benzimidazole Derivative XY123 in Prostate Cancer Treatment	2
Electrochemical Modification of Metronidazole and its Application as Antibacterial and Potential Drug Agent	2
Anti-cancer Potential of Pleurotus Mushroom: Detailed Insight on the Potential Bioactive Molecules, In vitro-In vivo Studies, and Formulation	2
Nanoemulgel-based delivery of 3-O-Acetyl-11-Keto-β-Boswellic Acid and basil oil for enhanced transdermal efficacy: In vitro anti-inflammatory and antioxidant assessment	2
In Silico, In Vitro and In Vivo Assessment of Acetylcholinesterase Inhibitory Activity of Theobromine Derivatives Containing an Arylpiperazine Fragment	2
Synthesis of Ethyl Methyl 4-aryl-1,4-dihydropyridine-3,5-dicarboxylates as Potential Calcium Channel Blockers for Hypertension	2
Mechanism of American Ginseng Against Type 2 Diabetes Mellitus Based on Network Pharmacology & Molecular Docking	2
Stilbene-based Derivatives as Potential Inhibitors of Bcl-2 Antiapoptotic Proteins: A Molecular Docking Study and ADMET Prediction	2
Rationale Design, Synthesis, and Pharmacological Evaluation of Isatin Analogues as Antiseizure Agents	2
Dynamic Comparison of Binding Pocket of Berberine Protein Crystals	2
3D-QSAR and Molecular Docking Studies of Pyrimidine-based EGFR Inhibitors	2
Structure-guided target prioritization of heterocyclic carboxamides for hyperlipidemia and obesity via cheminformatics, network biology, and docking studies	2
Synthesis and Biological Evaluation of Novel Oxazolidinone Derivatives Containing Dithiocarbamate Moiety as Antibacterial Agents	2
Medicinal Plants and Natural Products to Treat Obesity through Inhibiting Pancreatic Lipase: A Review (2020-2022)	2
Deciphering the Multi-target Pharmacological Mechanism of Sojae Semen Nigrum Acting on Breast Cancer through Integrating Network Pharmacology and Molecular Docking Approaches	2
Identification of Withanolide G as a Potential Inhibitor of Rho-associated Kinase-2 Catalytic Domain to Confer Neuroprotection in Ischemic Stroke	2
Mechanism of Yangxuetongmai Decoction in treating essential hypotension: A network pharmacology, Mendelian randomization and molecular docking strategy analysis	2
Conducting 2D and 3D QSAR Analyses and Molecular Docking Studies of Analogues of 2-(1-(1,3,4-thiadiazol-2-yl)piperidin-4-yl)ethan-1-ol with the Aim of Identifying Promising Drug Candidates for Targeti	2
In silico Investigation of the Pro-apoptotic Potential of Syringic Acid Analog	2
In Silico Studies of Piperidine Derivatives as Protein Kinase B Inhibitors through 3D-QSAR, Molecular Docking and Molecular Dynamics Simulation	2
Targeting Angiotensin-converting Enzyme Inhibitor via Enalapril Reduces Postsurgical Adhesion Band Formation	2
Thiamine: A Natural Peroxisome Proliferator-Activated Receptor Gamma (PPAR-γ) Activator	2
Susceptibility testing of Escherichia coli and Salmonella enterica to plant essential oils and commercial antibiotics	2
Discovering Drug Candidates for Charcot Marie Tooth Disease Type-2	2
Existing Drug Repurposing for Glioblastoma to Discover Candidate Drugs as a New a Approach	2
Structural classification of HDAC inhibitors and cancer treatment prospects: A review	2
Pyrazolone Derivatives: Synthetic Chemistry, Exploring Pharmacological Activity - A Mini Review	2
In Silico and In Vitro Screening of Novel Pyridazine Analogs as Muscle Relaxant Agent on Acetylcholine Muscarinic Receptor	2
The mechanism of Peilian Ephehuang Prescription in the treatment of simple obesity based on network pharmacology and molecular docking technology	2
Tirzepatide: A First-in-class Twincretin for the Management of Type 2 Diabetes	2
Uncovering the Biological Applications of Cinnamic Acid Derivatives: A Patent Review	2
Mesalamine may be a Plausible Therapeutic Agent for the Management of Diabetic Wounds: A Computational Approach	2
Acenaphthotriazine Thio-triazole Derivatives as Anti-cancer Agents Triggering Cell Cycle Arrest in Breast Cancer Cells	2
Synthesis and Anticancer Activities of Novel Bis-chalcones Incorporating the 1,3-diphenyl-1H-pyrazole Moiety: In Silico and In Vitro Studies	2
Synthesis and Preliminary Biological Evaluation of New Phthalazinone Derivatives with PARP-1 and Cholinesterase Inhibitory Activities	2
Emerging Heterocyclic Epidermal Growth Factor Receptor Inhibitors for the Management of Cancer: A Chemical Review	2
Attacking the SARS-CoV-2 Replication Machinery with the Pathogen Box’s Molecules	2
Computational Studies on Isolated Compounds of Sclerochloa dura; their Efficacy towards Carbonic Anhydrase Inhibition and Anti-cancer Drug Targets	2
In vitro Antibacterial Activity of Dye Compounds	2
Insights into Evolutionary and Conservancy Analytics on Human Insulin Receptor Proteins	2
Cornus mas (Cornelian Cherry) Exerts Neuroprotective Effects on Cerebral Ischemia/Reperfusion Injury via Anti-inflammatory and Antioxidant Properties	2
Research Progress of Vitamin K2 Related Signal Pathways: A Literature Review	2
Network Pharmacological Analysis and Experimental Validation of Anti-lung Cancer Effect of Echinacea Purpurea	2
Neuroprotective Potential of Polydatin in Combating Parkinson’s Disease through the Inhibition of Monoamine Oxidase-B and Catechol-o-Methyl Transferase	2
In silico Identification of Fructose-1,6-biphosphatase Inhibitory Potentials of Xanthones Isolated from African Medicinal Plants: An Integrated Computational Approach	2