Letters in Drug Design & Discovery

Article	Citations
Repurposing Novel Antagonists for Targeting p7 Viroporin of HCV Using In Silico Approach	228
Ligand-based Pharmacophore Modeling, Molecular Docking and Simulation Studies for the Exploration of Natural Potent Antiangiogenic Inhibitors Targeting Heat Shock Protein 90	96
Innovative approaches in insulin delivery: Exploring molecular techniques and system developments	54
Recent Developments, Challenges and Opportunities in Targeting the KRAS Pathway	48
Synthesis, Molecular Docking Studies, and In vitro Anticancer Evaluation of Novel Tolfenamic Acid Derivatives	38
Plant Secondary Metabolites as Apoptosis-inducing Agents	37
Synthesis, Characterization, and Evaluation of Sulfonium Lipids as Potential Nonviral Gene Vectors	31
Computational Insights on Migraine and Anxiety in Association with BDNF	29
Positive Expression of Paired Box 5 (Pax5) was Associated with Age, Tumor Location, and Tumor Size of Patients with Gastrointestinal Neuroendocrine Tumors (NETs)	26
Computational Study of Lactucine and its Derivatives to Investigate its Anti-cancerous Properties Targeting Apoptosis-inducing Protein	26
An in-silico design of a novel ursodeoxycholic acid analogue for helminthiasis therapy	20
Exploring Novel PLK1 Inhibitors based on Computational Studies of 2,4-Diarylaminopyrimidine Derivatives	20
Molecular Docking, Molecular Dynamics Simulation, and Analysis of EGFR-derived Peptides against the EGF	20
Piperazine-based Semicarbazone Derivatives as Potent Urease Inhibitors: Design, Synthesis, and Bioactivity Screening	19
Synthesis and Antimicrobial Activity of Functional Derivatives of thiazolo[ 2,3-c][1,2,4]triazoles	19
Preparation of Levothyroxine Transdermal Gels and Preliminary Pharmacokinetic Study in Hypothyroidism Rat Model	19
Anti-cancerous Properties of the Synthesized Substituted Chromene Compounds and their Pharmacological Activities	18
Synthesis and Anticancer Activity of Oral Pt(IV) Prodrugs Containing α-furancarboxylate as an Axial Ligand	18
Synergy Potential of Ursolic Acid-Based Hybrid Molecules	18
Calcium-dependent neurotoxicity of lidocaine: Mechanistic insights and future directions	17
Regulation of Exosomes-Mediated circNR4A1 on Chemoresistance and Biological Effects of Oral Squamous Cell Carcinoma Cells	16
Molecular docking, DFT calculations, and molecular dynamics simulations in the computational investigation of hydrazone derivative potential as a COVID-19 receptor inhibitor	15
From stem cells to therapeutics: Advancing islet function restoration through mesenchymal stem cell-based drug research	15
A Review on Synthesis and Biological Potential of Dihydropyridines	15
From prediction to design: A machine learning model for de novo bioactive compounds and personalized biotherapeutics	15

Potent Small Molecules Inhibitors Discovery through Ligand-based Modelling for Effective Treatment of Parkinson’s Disease	14
Unifying Theory and Experiments: Multi-Target Pharmacology of Dajihan Pill Against Hyperlipidemia	14
Evaluation of the Impact of Pistacia atlantica Desf. Oleo-gum Resin on Complete Freund’s Adjuvant-induced Arthritis in a Wistar Rat Model	14
Study on the Mechanism of Sanqi in the Treatment of Disseminated Intravascular Coagulation-Based on Network Pharmacology and Molecular Docking Technology	13
Ligand-based Molecular Modeling of HDL Receptor SR-BI Inhibitors as Potent Anti-hyperlipidemic Agents	13
Restraint of Starch-hydrolyzing Enzyme in the Management of Postprandial Blood Glucose Level: An Alternative Approach	12
The effect of serotonergic receptors (5HT3) on seizure threshold and mitochondrial damage induced by amitriptyline in the mouse brain	12
Evolutionary History of Oncogenes and Tumor Suppressor Genes Families: The Ancestral Origin in Mammals and Duplication Patterns	12
Anti-colorectal Cancer Activity of Quinazoline Derivatives: A Comprehensive Review	12
Phytochemical Characterization and Screening of the Anti-Pneumonia (Anti-COVID-19, Anti-Fungal, and Anti-Bacterial) Activities of Cuscuta Campestris Extract	12
A Network Pharmacology Guided Mechanism of Action Study on Oldenlandia diffusa Against Osteosarcoma	12
Triptolide and quercetin coordinately regulate the network pharmacology mechanism of renal cancer	12
Antimicrobial Activity of Halogen- and Chalcogen-Functionalized Thiazoloquinazolines	12
Network pharmacology-guided and molecular dynamics-validated insights into rubia phytocompounds as potential therapeutics for pneumonia	11
Discovery of PDK1 protein-protein interaction site modulators by deep learning and MD Simulations	11
Matrine inhibits the malignant behaviors of nasopharyngeal cancer cells by directly targeting CTSL	11
The search for the holy grail: In silico design and analysis of a non-sedative third generation, cetirizine-derived H1R anti-histamine with reduced hERG toxicity	10
HS3ST2, regulated by METTL14 through m6A mechanisms, contributes to M1 macrophage polarization in chronic obstructive pulmonary disease	10
The Role of Aquatic Plants in Natural Products and Drug Discovery	10
Modified Release of Acetaminophen from Matrix Tablet Formulations: Influence of Tablet Geometry	10
QSAR of SARS-CoV-2 Main Protease Inhibitors Utilizing Theoretical Molecular Descriptors	10
Implementation of PLGA-based Nanoparticles for Treatment of Colorectal Cancer	10
Anti-Tumor Activity of Indole: A Review	9
Croton caudatus Geiseler: Ethnomedicinal roots, phytochemical diversity, and anticancer relevance with implications for hepatocellular carcinoma	9
The Essential Role of Herbal-based Therapies in Combatting Acne Vulgaris	9
Design, Synthesis, and In vitro Biological Activities of Matrine Skeleton Derivatives as Potential Cancer Inhibitors	9
Cardiovascular drug use and Alzheimer’s disease: A systematic review of clinical evidence	9
Effect and safety of modified-release insulin-loaded liposome prototypes on glycemia in experimental models of type 1 diabetes mellitus	9
Integrating bioinformatics and experimental validation identifies MELK as a key target of Daurisoline against hepatocellular carcinoma	9
WITHDRAWN: Synthesis and Anticancer Activity of Newly Substituted 1,3,4-thiadiazole Derivatives: A Novel Class of Anticancer Agents	9
Advanced Oral Drug Delivery Systems for Combating and Preventing Paediatric Periodontal Disease	9
Design of VEGFR2 Inhibitors: Construction and Screening of Virtual Compound Libraries	9
Unveiling the effects of isoflurane on the cell proliferation, migration, invasion, and apoptosis of colorectal cancer cells in vitro via the PI3K/AKT/NF-κB pathway	9
Synthetic PARP-1 Inhibitors Reported During the Last Decade	9
Recent Advances in Drug Design and Delivery Across Biological Barriers Using Computational Models	9
Antimicrobial Activities of Substituted 4-N-alkylated-2-trifluoromethylquinoline Analogs Against Nontuberculous Mycobacteria	9
The Effects of Trigonella Foenum-graecum L. on Post-surgical Adhesion Band Formation	9
Exploring the mechanism of Squamocin inhibits oral squamous cell carcinoma malignant progression by targeting peroxisome proliferator activated receptor-gamma based on network pharmacology and molecul	8
Insight View on the Pharmacological Potential and Bio-active Components of Ginger	8
A Scoping Review on Recent Progress on Purpurin and its Derivatives	8
The Newly Proposed Mechanism of Cardiomyocyte Protection of Carvedilol- Anti-Apoptosis Pattern of Carvedilol in Anoxia by Inducing Autophagy Partly through the AMPK/mTOR Pathway	8
Docking Study on Caspase 3 Inhibitors As Potential Drugs For Traumatic Brain Cell Apoptosis	8
Computational design and screening of novel dipeptide analogues as potent antileprotic agents against alanine racemase and ligase	8
Synergistic anticancer effects of Dracaena cinnabari and Aloe perryi extracts on colorectal cancer cells: A flow cytometry analysis of toxicity, cell cycle, apoptosis, and autophagy	8
Network pharmacology combined with pharmacology to explore the mechanism of Zengye Runzao Decoction in treating Sjögren's Syndrome	8
Elucidating the mechanism of ferulic acid in treating ischemic stroke based on network pharmacology and multi-omics analysis	8
Formulation Development and Assessment of Solid Dispersion and Hydrotropy for BCS Class II Drug Solubility Enhancement	7
Analysis of Ultrasound Supported Antimicrobial and Antibiofilm Activities of Disinfection By-product Bromochloroacetonitrile	7
WITHDRAWN: Iodinated Curcumin as a Novel Anti-bacterial Agent to Combat Methicillin-resistant Staphylococcus aureus in Bovine Mastitis: In Silico Analysis, Synthesis and In Vitro Evaluation	7
Bioinformatic Screening of Compounds from Iranian Lamiaceae Family Members against SARS-CoV-2 Spike Protein	7

Neuroprotective and Nootropic Evaluation of some Important Medicinal Plants in Dementia: A Review	7
Exploring the Potential of Avenanthramides and their Analogues as α-Glucosidase Inhibitors for Type 2 Diabetes Treatment Utilizing Virtual Screening, Molecular Dynamics, and Drug-likeness Predictions	7
Discovery of Natural Compounds as SARS-CoV-2’s Main Protease Inhibitors by Docking-based Virtual Screening	7
Exploring Nature’s Treasure for Drug Discovery	7
WITHDRAWN: The Radix Achyranthes Bidentata Regulates BMSCsderived Chondrogenic Differentiation by Modulating Rab39a and Activating SOX9 and RHOA/RACK1 Signaling	7
Physically Crosslinked Polymeric Network for Controlled and Mucoadhesive Release of Miconazole for Topical Ocular Delivery	7
Whole-cell Lipase Catalytic Synthesis of Short-chain Fragrance Esters using Aspergillus flavus	7
In vitro Cholinesterase Inhibitory Activities of Piper betle Stem and their Correlation with In silico Docking Studies of its Phytoconstituents	7
Mitigation of cyclophosphamide-induced hepatoxicity by Allium ampeloprasum Subsp Iranicum: A potential protective agent in chemotherapy	7
Molecular Docking: Principles, Advances, and Its Applications in Drug Discovery	7
A Comprehensive Review of the Advancement in Omic Technologies in the Field of Drug Discovery and Development	7
Advances in Isatin-derived Compounds for Modern Cancer Therapy: A Comprehensive Review	7
Up-to-date Combinational Polymeric Approaches for the Enhancement of Drug Absorption and Membrane Transductivity	7
Design, Synthesis, and Assay of New N-acyl-4-(4-aminoalkoxy- phenyl)- thiazole-2-amine Derivatives as Acetylcholinesterase Inhibitors	7
Design, Synthesis, and In vitro Anticancer Activity of Novel Chrysin Derivatives	7
Synthesis and Pharmacological Activity of 4', 4''- bit Modified Curcumin Derivatives	7
Molecular Docking of the Terpenes in Gorgonian Corals to COX-2 and iNOS Enzymes as Anti-Inflammatory	7
Targeting EGFR/PI3K/AKT signaling mediates the anti-tumor effect of Ginsenoside CK in oral cancer	7
Rings in “Lead-like Drugs”	6
Baicalein Promotes Acute Myeloid Leukemia Cell Autophagy via miR-424 and the PTEN/PI3K/AKT/mTOR Pathway	6
QSAR Analysis and Molecular Docking Studies of Aryl Sulfonamide Derivatives as Mcl-1 Inhibitors and the Influence of Structure and Chirality on the Inhibitory Activity	6
Identification of active compounds and therapeutic mechanisms of traditional Chinese medicine for periarthritis of shoulder for promoting blood circulation and removing stasis (PBRS): A network pharma	6
Angiotensin-Converting Enzyme Inhibition Properties and Antioxidant Effects of Plants and their Bioactive Compounds as Cardioprotective Agent	6
Association of SARS-CoV-2 Infection and Triple Negative Breast Cancer (TNBC) A Computational Illustrative Study	6
“Thiophene”: A Sulphur Containing Heterocycle as a Privileged Scaffold	6
Identification of natural product-based S6K1 inhibitor by high-throughput virtual screening	6
Graviola Protects Against Hepatic Toxicity Associated with DMBA induced Breast Cancer via Restoration of Antioxidants and Attenuation of Inflammatory Pathways	6
Design, Synthesis, and Insecticidal Evaluation of New Benzoylureas Containing Carbamate Groups Based on the Bipartite Model of Sulfonylurea Receptor Binding Site	6
A Review on Biological Activity of Quinoline-based Hybrids	6
KBH4 assisted synthesis of ultra-large mesoporous silica nanosystem encapsulating paclitaxel and glucose oxidase for starvation/chemo-therapy	6
Design and Prediction of ADME/Tox Properties of Novel Magnolol Derivatives as Anticancer Agents for NSCLC Using 3D-QSAR, Molecular Docking, MOLCAD and MM-GBSA Studies	6
Novel 1,3,4-trisubstituted Pyrazolopyrimidine Derivatives Show Potent Antiproliferative Activity in Mantle Cell Lymphoma	6
Indolizines in focus: Synthetic approaches, biological profiles, and SAR perspectives, a review	6
Exploring DPP-IV inhibitors for diabetes treatment: A comprehensive study on molecular docking, molecular dynamics simulation, and in-vitro DPP-IV assay	6
Development and characterization of suppository formulation for rectal delivery of clarithromycin	6
Synthesis and biological evaluation of thiobarbituric acid derivatives as antioxidant and cytotoxic agents	6
Exposure of Bisphenol S on splenic injury causing inflammation in Wistar rat by histological analysis	6
Identifying TMPRSS2 Inhibitors by Drug Repurposing Screenings of Known fXIa Inhibitors: A Computational Study	6
Nitrogen-containing Heterocyclic Derivatives of 1,3-Thiazolidine-2,4- Diones as Dual Anti-inflammatory and Anti-oxidant Agents and their Docking Studies	6
The Inhibitory Effect and Mechanism of Action of Myricaria germanica Essential Oils on Skin Inflammation based on Network Pharmacology and Molecular Docking	6
In silico De Novo Discovery of Novel Target-specific Drug-like Bidentate Inhibitors of PTP 1B	5
Mechanism of Trigonella Foenum-graecum L. against Type 2 Diabetes Mellitus: Research on Network Pharmacology & Experimental Verification	5
A comprehensive in-silico approach (pharmacophoric QSAR and docking-based comparative intermolecular analysis) led to identifying new PIM2 kinase inhibitors for treating resistant lymphomas	5
Multi-omics integration reveals the candidate molecular regulatory network and pathway of aFGF regulating BMSCs to promote tendon-bone healing	5
Exploring Novel Benzopyran Derivatives as Antitubercular Agents	5
Essential Structural Profile of Novel Adenosine Derivatives as Antiplatelet Aggregation Inhibitors based on 3D-QSAR Analysis	5
The Contribution of the Rat Mesenteric Vascular Bed Model to Phytopharmacology with Computational Studies of the Main Vasorelaxant Phytochemicals	5
Discovery of anti-rheumatoid arthritis active components from Salvia miltiorrhiza and their potential dual "Anti-inflammatory and Cardiovascular Protective" mechanisms via a multi-scale computational	5
Emerging DNA- and RNA-based therapeutic strategies in hepatocellular carcinoma: A molecular approach to precision medicine	5
Towards Further Understanding the Role of Curcumin in Wound Healing: A Systems Biology Approach	5
An appraisal on biomolecular imaging in diagnosis of neurological disorders and innovation in clinical research	5
Polygenic Regulation by Flos Daturae in the Treatment of Breast Cancer: A Study based on Network Pharmacology and Bioinformatics	5
Network pharmacology, molecular docking, and experimental validation of dihydromyricetin attenuating LPS-induced acute lung injury by promoting FGFR1	5
Design and computational evaluation of novel 2,4-thiazolidinedione hybrids for potential anti-inflammatory activity	5
Development and evaluation of optimized molecularly imprinted polymer (MIP) for targeted drug delivery of 5-Fluorouracil	5
Synthesis and Biological Evaluation of Hydroxypropyl Ester of Mefenamic Acid as a Promising Prodrug	5
Efficacy and safety of PD-1/PD-L1 inhibitors for relapsed/metastatic nasopharyngeal carcinoma: A systematic review and meta-analysis	5
The Therapeutic Potential of Metformin for Attenuating Postsurgical Adhesion Band Formation	5
Acknowledgements to Reviewers	5
Preparation of Metformin Biodegradable Polymeric Microparticles by O/O Emulsion Solvent Evaporation: A 32 Full Factorial Design Approach	5
Demonstration of Interaction between Carbapenem Group Antibiotics and Different Immunosuppressant Drugs by Molecular Docking	5
A Novel Drug Delivery Platform Against Bacterial Resistance: Synthesis and Characterization of Ciprofloxacin-loaded MCM-41 Mesoporous Silica Nanoparticle	5
Rational Design and Synthesis of Novel Benzimidazole Derivatives as Potential β-Glucosidase Inhibitors	5
Integrating single-cell sequencing and network pharmacology to reveal the mechanisms of matrine against ulcerative colitis	5
Nanotechnology-Based Approaches for Nose-to-Brain Drug Delivery in Neurodegenerative Diseases	5
Potential of Surface Functionalized Nanomaterials in Innovative Drug Development: A Mini-review	5
Naphthoquinone-triazole hybrids as anti-diabetic agents: An exploration of in silico and in vitro α-glucosidase and α-amylase inhibition	5
Discovery of MAO-A Inhibitors as Antidepressant Based on Virtual Screening	5
Molecular Docking, Acute Toxicity and Antibacterial Study of Debilon and Phorbasterone-B Extracted from Rhodophyta	5
Molecular Modeling of some 1,3,4-Oxadiazole Derivatives as EGFR Inhibitors for the Treatment of Cancer	5
Bdellovibrio bacteriovorus Therapy, an Emerging Alternative to Antibiotics	5
Quantum Mechanics Modeling of Oxetanes as Epoxide Hydrolase Substrates	5
Integrated m⁶A and transcriptome analysis in a smoking-induced lung injury model reveals key methylated genes and computationally predicts potential therapeutic candidates	5
Virtual Screening of Telaprevir and Danoprevir Derivatives for Hepatitis C Virus NS3/4A Protease Inhibitors	4
USP13 stabilizes EPHA2 to promote M2 macrophage polarization and cervical cancer progression	4
Virtual Screening, Molecular Docking, and Physiochemical Analysis of Novel 1,3-diphenyl-2-propene-1-one as Dual COX-2/5-LOX Inhibitors	4
Ethosomes: Novel Vesicular Carriers for Effective Transdermal Delivery of Natural Therapeutics	4
The Importance of Salicylic Acid, Humic Acid and Fulvic Acid on Crop Production	4
In silico design, one pot synthesis and pharmacological evaluation of tetra-substituted imidazoles as potential atypical antipsychotics	4
Computational strategies for drug discovery in neurodegeneration: Targeting Alzheimer’s and Parkinson’s disease	4

Evolution-based fragment growth protocol for design of potent RsmD inhibitors in mycobacterium tuberculosis	4
Bioactive Natural Leads and Traditional Herbal Plants in the Management of Inflammatory Bowel Diseases: A Brief Review	4
Metformin Sensitizes Cisplatin-induced Apoptosis Through Regulating Nucleotide Excision Repair Pathway In Cisplatin-resistant Human Lung Cancer Cells	4
Exploring the antimicrobial and biofilm inhibitory potential of Citrus limetta peel essential oil against multidrug-resistant Shigella: In vitro and in silico insights	4
Exploring the mechanism of action of tolvaptan in the treatment of cor pulmonale pulmonary hypertension using network pharmacology and animal-based experiments	4
Investigating the mechanism of curcumin against LUAD malignant progression and macrophage M2 polarization based on network pharmacology, bioinformatics, and molecular docking	4
Integration of single-cell sequencing and multi-omics approaches with pharmacological analysis to unveil biomarkers and mechanisms of traditional Chinese medicine in treating heart diseases	4
Exploration of the mechanism of quercetin against GDM based on network pharmacology and molecular docking	4
Role of a Dual Inhibitor of RAS/PI3K/AKT and RAS/RAF/MEK on Post-surgical Adhesion Band Formation	4
Natural Antioxidants of the Underutilized and Neglected Plant Species of Asia and South America	4
Based on the Network Pharmacology to Analyze the Effect of Chuanxiong in Improving Diabetic Nephropathy	4
An Ultrasound-assisted Three Component Protocol for the Regio and Stereo-selective Synthesis of Some Novel Dispiroheterocycles and Their Biological Evaluation as Anti-inflammatory, Anti-obesity Agents	4
Novel 2-pyridone Analogs with Anti-cancer Activity: Synthesis, In silico, and In vitro Evaluation	4
GelMA@DFO hydrogel promotes bone regeneration via HIF-1α-mediated angiogenesis	4
Palladium (II)-N-heterocyclic Carbene Complexes: Synthesis, Molecular Docking, UV-Vis Absorption and Enzyme Inhibition	4
Exploring the mechanism of Grifolin in inhibiting the malignant progression of colon cancer cells mediated by the PDGFRB/PI3K/AKT signaling pathway based on bioinformatics analysis and network pharmac	4
Optimizing therapeutic strategies for hypertensive disorders of pregnancy through multi-omics integration and network pharmacology	4
A Review of the Azasteroid-type 5-alpha Reductase Inhibitors for the Management of Benign Prostatic Hyperplasia	4
Network Pharmacological Study of the Active Ingredient of Panax Notoginseng Saponins for the Treatment of Lung Cancer by Inhibiting AKR1C3	4
Structure-guided Development of Novel Benzothiophene Derivatives as PLK1-PBD Inhibitors	4
The evolving role of novel anesthetic agents for obstetric and gynecological anesthesia: The multidimensional value from esketamine to dexmedetomidine	4
Perillaldehyde Building Block’s Derivatives: Targeted Bioactivities and Molecular Docking	4
Multi-modal investigation of doxorubicin-induced osteoporosis: Network toxicology, machine learning, and imaging techniques	4
Design and Screening of KLHL22 Inhibitors by Homology Modeling, Molecular Docking, and Molecular Dynamics Simulation	4
Phytosome: An Effective Transdermal Drug Delivery System for Phytoconstituents	4
CD44 as the Target Site for Hyaluronic Acid in Favor of Colitis Management	4
Recent Advances in Therapeutic Strategies against Hydatid Cysts using Nanomaterials: A Systematic Review	4
Synthesis and Biological Activity of 2-pyridone Derivatives: A Mini Review	4
Conjugation of Mycophenolic Acid with Dextran: A Potential Strategy for Colon-Targeted Delivery for Mitigation of Inflamed Colon in Ulcerative Colitis	4
Molecular Docking, Dynamics Simulation, and Physicochemical Analysis of Some Phytochemicals as Antiplatelet Agents	4
Thymoquinone suppresses cell growth and induces ferroptosis in renal cell carcinoma by reducing SERPINH1 expression	4
Machine learning and molecular docking identify the anti-tumor activity of lobetyolin in non-small cell lung cancer by targeting the oncogenic factor GART	4
Lycopene-Loaded Solid Lipid Nanoparticles: Preparation, Characterization, ROS-Scavenging, and In vitro Anti-Melanogenesis Evaluations	4
Exploring the mechanism of shikonin in ameliorating allergic rhinitis through integrated bioinformatics analysis, network pharmacology, and experimental validation	4
Imperatorin remits malignant progression of endometrial cancer by silencing E2F1/SLC3A2	4
Garcinol: An emerging epigenetic modifier with versatile anticancer properties	4
Synthesis, Computational Study, and Anticonvulsant Activity of Newly Synthesized 2-aminobenzothiazole Derivatives	4
Structure-based design of plant-based dual inhibitors targeting AURKA1 and HDAC2 as potential anticancer agents	4
Polyherbal DPP-IV inhibitors: In silico and in vivo insights into anti-diabetic drug design	4
T cell activation and TCRs as an immunotherapeutic approach in cancer	4
Identification of Potential Inhibitors for Severe Acute Respiratory Syndrome-related Coronavirus 2 (SARS-CoV-2) Angiotensin-converting Enzyme 2 and the Main Protease from Anatolian Traditional Plants	3
Investigating the flavonoid compounds of citrus peel and their pharmacological mechanism to combat breast cancer through system pharmacology and experimental verification	3
Exploring N-acetyl-1,3,4-oxadiazoline derivatives against Alzheimer's disease: ADMET, molecular docking, and DFT analysis	3
The effects of hydrogen-rich water on gut microbiota and related health outcomes: A systematic review	3
Development of Potential Antidiabetic Agents using 2D and 3D QSAR, Molecular Docking and ADME Properties In-silico Studies of α-amylase Inhibitors	3
Potent α-glucosidase and tyrosinase inhibition by thiophene-based Schiff bases: Experimental and computational evaluation	3
Electrochemical Modification of Metronidazole and its Application as Antibacterial and Potential Drug Agent	3
Exploration of the potential molecular mechanism of magnolol in colorectal cancer treatment based on network pharmacology and molecular docking	3
In silico Investigation of Identified Major Metabolites from Coffea Arabica Leaves against Parkinson’s Disease Target Proteins for Neuroprotective Drug Development	3
Synthesis and Biological Evaluation of Novel Oxazolidinone Derivatives Containing Dithiocarbamate Moiety as Antibacterial Agents	3
Synthesis and Anti-proliferative, Tyrosine Kinases Inhibitions of New Xanthene Derivatives and their Morphological Studies	3
Novel STAT3 Inhibitor Exerts Anti-breast Cancer Effects Both In vitro and In vivo	3
Computational Study of Designed Peptide Analogs against Pseudomonas aeruginosa as a Possible Inhibitor of LptD Membrane Protein	3
Ezetimibe Inhibits Cell Viability and Invasion by Suppressing PI3K/AKT Signaling Pathway in Human Osteosarcoma Cells	3
Structure-guided target prioritization of heterocyclic carboxamides for hyperlipidemia and obesity via cheminformatics, network biology, and docking studies	3
Synthesis, characterization, and neuroprotective effect of taxifolin-conjugated gold nanoparticles against amyloid βeta induced Alzheimer’s disease	3
Exploring the Molecular Mechanisms of Astragalus membranaceus in Treating Pre-eclampsia using Network Pharmacology and Molecular Docking	3
Identification of C3 as a target of Genistein, Isotretinoin and Rofecoxib in age-related macular degeneration	3
Thiamine: A Natural Peroxisome Proliferator-Activated Receptor Gamma (PPAR-γ) Activator	3
Insights into Evolutionary and Conservancy Analytics on Human Insulin Receptor Proteins	3
Organoid models in lung cancer research: A multidimensional perspective from basic biology to precision medicine	3
Neuroprotective Potential of Polydatin in Combating Parkinson’s Disease through the Inhibition of Monoamine Oxidase-B and Catechol-o-Methyl Transferase	3
Formulation and Characterization Studies of Paclitaxel Incorporated Kollidon® SR and Chitosan Nanoparticles: An In vitro Evaluation for Potential Use for Colorectal Cancer Treatment	3
Targeting Angiotensin-converting Enzyme Inhibitor via Enalapril Reduces Postsurgical Adhesion Band Formation	3
Synthesis, Characterization, and Evaluation of Antioxidant Activities of 2-(1-(Substituted phenyl)ethylidene)-1-(4,6-dimethylpyrimidin-2-yl)hydrazines	3
Coronavirus Inhibitory Activity of Tamarind Indica	3
Diversely Functionalized Pyridine Ring-fused Heterocycles and their Anticancer Properties	3
Amidoximes and their Cyclized Analogue Oxadiazoles as New Frontiers in Chemical Biology: Mini Review	3
Mesalamine may be a Plausible Therapeutic Agent for the Management of Diabetic Wounds: A Computational Approach	3
In silico Investigation of the Pro-apoptotic Potential of Syringic Acid Analog	3
1,2,4 Triazoles and 1,2,4 Oxadiazoles Scaffold as SGLT2 Inhibitors: Molecular Docking and ADMET Studies	3
Efficacy of Ozonated Olive Oil as a Topical Treatment for Dermatophytosis Caused by T. mentagrophytes in Rat Model	3
Research on the mechanism by which quercetin affects ferroptosis in breast cancer cells through regulating USP9X/PIAS4	3
Berberine suppresses the malignant progression of ovarian cancer by downregulating HSP90AA1 expression	3
AI-driven target discovery and clinical development of candidate drugs for idiopathic pulmonary fibrosis: A review	3
Molecular mechanisms of renoprotection and safety profile of Salvia miltiorrhiza (Danshen)	3
Integrating bioinformatics and machine learning to analyze molecular biomarkers, immune infiltration mechanisms, and small-molecule therapeutic candidates for gallstones	3
15, 16-dihydrotanshinone I mitigates right ventricular hypertrophy in pulmonary arterial hypertension by suppressing HIF1A/CXCR4 signaling	3
Anti-cancer Potential of Pleurotus Mushroom: Detailed Insight on the Potential Bioactive Molecules, In vitro-In vivo Studies, and Formulation	3
In-silico Studies, Synthesis, and Evaluation of Anti-inflammatory Activity of Novel Pyrimidine Scaffold	3
Survey on Medicinal Plants and Herbs in Traditional Iranian Medicine with Anti-oxidant, Anti-viral, Anti-microbial, and Anti-inflammation Properties	3
Geniposide regulates mitochondrial dynamics and PINK1/Parkin-mediated mitophagy to mitigate myocardial ischemia–reperfusion injury in rats	3
Research Progress of Vitamin K2 Related Signal Pathways: A Literature Review	3
The Synthesis and Pharmacological Activity of Ursolic Acid Derivatives Modified at C-28 and C-3 Sites	3
Synthetic Transformation of 4-fluorobenzoic Acid to 4-fluorobenzohydrazide Schiff Bases and 1,3,4-Oxadiazole Analogs having DPPH Radical Scavenging Potential	3
Susceptibility testing of Escherichia coli and Salmonella enterica to plant essential oils and commercial antibiotics	3
Effects of Compound in Hedyotis diffusa Willd against Acute Myeloid Leukemia: An In Silico and In Vitro Study	3
Virtual Screening of Novel Phytocompound(s) with Potential to Combat Mycobacterium tuberculosis Infection	3
Gm15886-Hipk1 Signaling Pathway Plays Important Roles in the Pathogenesis of Bronchopulmonary Dysplasia Mice	3
Chemical Composition, In vitro and In silico Evaluation of Essential Oil Extracted from Mentha Piperita L. for Lung Cancer	3
Design and Synthesis of an Hsp90 and HDAC Dual Inhibitor as Antitumor Agent	3
The mechanisms of Mahuang decoction in treating COPD: Insights from network pharmacology and in vivo studies	3
Treatment of Narcolepsy: A Rare Disease of Unknown Etiology	3
Network Pharmacological Analysis and Experimental Validation of Anti-lung Cancer Effect of Echinacea Purpurea	3
A Linear and Nonlinear QSAR Analysis of Benzimidazole Derivative XY123 in Prostate Cancer Treatment	3