Letters in Drug Design & Discovery

Article	Citations
Preparation of Levothyroxine Transdermal Gels and Preliminary Pharmacokinetic Study in Hypothyroidism Rat Model	171
Piperazine-based Semicarbazone Derivatives as Potent Urease Inhibitors: Design, Synthesis, and Bioactivity Screening	85
Exploring Novel PLK1 Inhibitors based on Computational Studies of 2,4-Diarylaminopyrimidine Derivatives	39
Molecular Docking, Molecular Dynamics Simulation, and Analysis of EGFR-derived Peptides against the EGF	33
Repurposing Novel Antagonists for Targeting p7 Viroporin of HCV Using In Silico Approach	33
Innovative approaches in insulin delivery: Exploring molecular techniques and system developments	30
Ligand-based Pharmacophore Modeling, Molecular Docking and Simulation Studies for the Exploration of Natural Potent Antiangiogenic Inhibitors Targeting Heat Shock Protein 90	30
A Review on Synthesis and Biological Potential of Dihydropyridines	28
Recent Developments, Challenges and Opportunities in Targeting the KRAS Pathway	27
Synthesis and Anticancer Activity of Oral Pt(IV) Prodrugs Containing α-furancarboxylate as an Axial Ligand	27
Synthesis, Molecular Docking Studies, and In vitro Anticancer Evaluation of Novel Tolfenamic Acid Derivatives	25
Plant Secondary Metabolites as Apoptosis-inducing Agents	24
Synthesis, Characterization, and Evaluation of Sulfonium Lipids as Potential Nonviral Gene Vectors	23
Computational Insights on Migraine and Anxiety in Association with BDNF	19
Positive Expression of Paired Box 5 (Pax5) was Associated with Age, Tumor Location, and Tumor Size of Patients with Gastrointestinal Neuroendocrine Tumors (NETs)	18
Screening and Structure-Activity Relationship of Potential Compounds against Proposed Targets of COVID-19 Infection	18
Computational Study of Lactucine and its Derivatives to Investigate its Anti-cancerous Properties Targeting Apoptosis-inducing Protein	17
Anti-cancerous Properties of the Synthesized Substituted Chromene Compounds and their Pharmacological Activities	15
Synergy Potential of Ursolic Acid-Based Hybrid Molecules	15
Mechanistic Investigation of Glycyrrhiza uralensis Effects against Respiratory Ailments: Application of Network Pharmacology and Molecular Docking Approaches	14
Regulation of Exosomes-Mediated circNR4A1 on Chemoresistance and Biological Effects of Oral Squamous Cell Carcinoma Cells	14
From stem cells to therapeutics: Advancing islet function restoration through mesenchymal stem cell-based drug research	12
Design, Synthesis and In Vitro Anticancer Activity of Benzo[c]chromen-6- one-linked 1,2,3-Triazole	12
Synthesis and Antimicrobial Activity of Functional Derivatives of thiazolo[ 2,3-c][1,2,4]triazoles	12
Study on the Mechanism of Sanqi in the Treatment of Disseminated Intravascular Coagulation-Based on Network Pharmacology and Molecular Docking Technology	11

Evaluation of the Impact of Pistacia atlantica Desf. Oleo-gum Resin on Complete Freund’s Adjuvant-induced Arthritis in a Wistar Rat Model	11
Unifying Theory and Experiments: Multi-Target Pharmacology of Dajihan Pill Against Hyperlipidemia	11
Potent Small Molecules Inhibitors Discovery through Ligand-based Modelling for Effective Treatment of Parkinson’s Disease	11
The Essential Role of Herbal-based Therapies in Combatting Acne Vulgaris	11
Implementation of PLGA-based Nanoparticles for Treatment of Colorectal Cancer	10
Anti-Tumor Activity of Indole: A Review	10
The search for the holy grail: In silico design and analysis of a non-sedative third generation, cetirizine-derived H1R anti-histamine with reduced hERG toxicity	10
Ligand-based Molecular Modeling of HDL Receptor SR-BI Inhibitors as Potent Anti-hyperlipidemic Agents	10
Triptolide and quercetin coordinately regulate the network pharmacology mechanism of renal cancer	10
Effect and safety of modified-release insulin-loaded liposome prototypes on glycemia in experimental models of type 1 diabetes mellitus	10
Synthetic PARP-1 Inhibitors Reported During the Last Decade	10
The effect of serotonergic receptors (5HT3) on seizure threshold and mitochondrial damage induced by amitriptyline in the mouse brain	10
Restraint of Starch-hydrolyzing Enzyme in the Management of Postprandial Blood Glucose Level: An Alternative Approach	9
Modified Release of Acetaminophen from Matrix Tablet Formulations: Influence of Tablet Geometry	9
Antimicrobial Activity of Halogen- and Chalcogen-Functionalized Thiazoloquinazolines	9
Evolutionary History of Oncogenes and Tumor Suppressor Genes Families: The Ancestral Origin in Mammals and Duplication Patterns	9
The Role of Aquatic Plants in Natural Products and Drug Discovery	8
Phytochemical Characterization and Screening of the Anti-Pneumonia (Anti-COVID-19, Anti-Fungal, and Anti-Bacterial) Activities of Cuscuta Campestris Extract	8
The Newly Proposed Mechanism of Cardiomyocyte Protection of Carvedilol- Anti-Apoptosis Pattern of Carvedilol in Anoxia by Inducing Autophagy Partly through the AMPK/mTOR Pathway	8
A Network Pharmacology Guided Mechanism of Action Study on Oldenlandia diffusa Against Osteosarcoma	8
QSAR of SARS-CoV-2 Main Protease Inhibitors Utilizing Theoretical Molecular Descriptors	8
Formulation Development and Assessment of Solid Dispersion and Hydrotropy for BCS Class II Drug Solubility Enhancement	8
Anti-colorectal Cancer Activity of Quinazoline Derivatives: A Comprehensive Review	8
A Comprehensive Review of the Advancement in Omic Technologies in the Field of Drug Discovery and Development	8
A Comparative Computational Analysis Approach to Predict Significant Protein-Protein Interactions of Human and Vancomycin Resistant Enterococcus faecalis (VRE) to Prioritize Potential Drug Targets	7
Insight View on the Pharmacological Potential and Bio-active Components of Ginger	7
Analysis of Ultrasound Supported Antimicrobial and Antibiofilm Activities of Disinfection By-product Bromochloroacetonitrile	7
Exploring the Potential of Avenanthramides and their Analogues as α-Glucosidase Inhibitors for Type 2 Diabetes Treatment Utilizing Virtual Screening, Molecular Dynamics, and Drug-likeness Predictions	7
Design of VEGFR2 Inhibitors: Construction and Screening of Virtual Compound Libraries	7
Saponins-uptake and Targeting Issues for Brain-specific Delivery for Enhanced Cell Death Induction in Glioblastoma	7
Design, Synthesis, and In vitro Biological Activities of Matrine Skeleton Derivatives as Potential Cancer Inhibitors	7
The Effects of Trigonella Foenum-graecum L. on Post-surgical Adhesion Band Formation	7
Exploring Nature’s Treasure for Drug Discovery	7
Advances in Isatin-derived Compounds for Modern Cancer Therapy: A Comprehensive Review	7
WITHDRAWN: Synthesis and Anticancer Activity of Newly Substituted 1,3,4-thiadiazole Derivatives: A Novel Class of Anticancer Agents	7
Advanced Oral Drug Delivery Systems for Combating and Preventing Paediatric Periodontal Disease	7
Antimicrobial Activities of Substituted 4-N-alkylated-2-trifluoromethylquinoline Analogs Against Nontuberculous Mycobacteria	7
Synthesis and Pharmacological Activity of 4', 4''- bit Modified Curcumin Derivatives	6
Synergistic anticancer effects of Dracaena cinnabari and Aloe perryi extracts on colorectal cancer cells: A flow cytometry analysis of toxicity, cell cycle, apoptosis, and autophagy	6
WITHDRAWN: The Radix Achyranthes Bidentata Regulates BMSCsderived Chondrogenic Differentiation by Modulating Rab39a and Activating SOX9 and RHOA/RACK1 Signaling	6
A Review on Biological Activity of Quinoline-based Hybrids	6
Whole-cell Lipase Catalytic Synthesis of Short-chain Fragrance Esters using Aspergillus flavus	6
Bioinformatic Screening of Compounds from Iranian Lamiaceae Family Members against SARS-CoV-2 Spike Protein	6
Baicalein Promotes Acute Myeloid Leukemia Cell Autophagy via miR-424 and the PTEN/PI3K/AKT/mTOR Pathway	6
The Inhibitory Effect and Mechanism of Action of Myricaria germanica Essential Oils on Skin Inflammation based on Network Pharmacology and Molecular Docking	6
Docking Study on Caspase 3 Inhibitors As Potential Drugs For Traumatic Brain Cell Apoptosis	6
A Scoping Review on Recent Progress on Purpurin and its Derivatives	6
Recent Advances in Drug Design and Delivery Across Biological Barriers Using Computational Models	6
Discovery of Natural Compounds as SARS-CoV-2’s Main Protease Inhibitors by Docking-based Virtual Screening	6
Identifying TMPRSS2 Inhibitors by Drug Repurposing Screenings of Known fXIa Inhibitors: A Computational Study	6

QSAR Analysis and Molecular Docking Studies of Aryl Sulfonamide Derivatives as Mcl-1 Inhibitors and the Influence of Structure and Chirality on the Inhibitory Activity	6
Association of SARS-CoV-2 Infection and Triple Negative Breast Cancer (TNBC) A Computational Illustrative Study	6
Molecular Docking: Principles, Advances, and Its Applications in Drug Discovery	6
Synthesis and Studies of Anticancer and Antimicrobial Activity of New Phenylurenyl Chalcone Derivatives	6
Physically Crosslinked Polymeric Network for Controlled and Mucoadhesive Release of Miconazole for Topical Ocular Delivery	6
WITHDRAWN: Iodinated Curcumin as a Novel Anti-bacterial Agent to Combat Methicillin-resistant Staphylococcus aureus in Bovine Mastitis: In Silico Analysis, Synthesis and In Vitro Evaluation	6
Up-to-date Combinational Polymeric Approaches for the Enhancement of Drug Absorption and Membrane Transductivity	6
In vitro Cholinesterase Inhibitory Activities of Piper betle Stem and their Correlation with In silico Docking Studies of its Phytoconstituents	6
Molecular Docking, Acute Toxicity and Antibacterial Study of Debilon and Phorbasterone-B Extracted from Rhodophyta	5
Acknowledgements to Reviewers	5
A comprehensive in-silico approach (pharmacophoric QSAR and docking-based comparative intermolecular analysis) led to identifying new PIM2 kinase inhibitors for treating resistant lymphomas	5
Molecular Docking of the Terpenes in Gorgonian Corals to COX-2 and iNOS Enzymes as Anti-Inflammatory	5
Angiotensin-Converting Enzyme Inhibition Properties and Antioxidant Effects of Plants and their Bioactive Compounds as Cardioprotective Agent	5
Identification of Novel Nrf2 Activator via Protein-ligand Interactions as Remedy for Oxidative Stress in Diabetes Mellitus	5
KBH4 assisted synthesis of ultra-large mesoporous silica nanosystem encapsulating paclitaxel and glucose oxidase for starvation/chemo-therapy	5
Design, Synthesis, and Assay of New N-acyl-4-(4-aminoalkoxy- phenyl)- thiazole-2-amine Derivatives as Acetylcholinesterase Inhibitors	5
Novel 1,3,4-trisubstituted Pyrazolopyrimidine Derivatives Show Potent Antiproliferative Activity in Mantle Cell Lymphoma	5
“Thiophene”: A Sulphur Containing Heterocycle as a Privileged Scaffold	5
Synthesis and Biological Evaluation of Hydroxypropyl Ester of Mefenamic Acid as a Promising Prodrug	5
The Contribution of the Rat Mesenteric Vascular Bed Model to Phytopharmacology with Computational Studies of the Main Vasorelaxant Phytochemicals	5
The Therapeutic Potential of Metformin for Attenuating Postsurgical Adhesion Band Formation	5
Rings in “Lead-like Drugs”	5
Neuroprotective and Nootropic Evaluation of some Important Medicinal Plants in Dementia: A Review	5
Design, Synthesis, and Insecticidal Evaluation of New Benzoylureas Containing Carbamate Groups Based on the Bipartite Model of Sulfonylurea Receptor Binding Site	5
Design, Synthesis, and In vitro Anticancer Activity of Novel Chrysin Derivatives	5
Graviola Protects Against Hepatic Toxicity Associated with DMBA induced Breast Cancer via Restoration of Antioxidants and Attenuation of Inflammatory Pathways	5
Mitigation of cyclophosphamide-induced hepatoxicity by Allium ampeloprasum Subsp Iranicum: A potential protective agent in chemotherapy	5
Potential of Surface Functionalized Nanomaterials in Innovative Drug Development: A Mini-review	5
Mechanism of Trigonella Foenum-graecum L. against Type 2 Diabetes Mellitus: Research on Network Pharmacology & Experimental Verification	5
Essential Structural Profile of Novel Adenosine Derivatives as Antiplatelet Aggregation Inhibitors based on 3D-QSAR Analysis	5
Design of Dual COX-2 and 5-LOX Inhibitors with Iron-Chelating Properties Using Structure-Based and Ligand-Based Methods	5
Exploring Novel Benzopyran Derivatives as Antitubercular Agents	5
Morelloflavone as Potential Anticancer Agent Against MCF-7 Breast Cancer Cell Lines: In vitro and In silico Studies	5
Nitrogen-containing Heterocyclic Derivatives of 1,3-Thiazolidine-2,4- Diones as Dual Anti-inflammatory and Anti-oxidant Agents and their Docking Studies	5
Development and characterization of suppository formulation for rectal delivery of clarithromycin	5
Design and Prediction of ADME/Tox Properties of Novel Magnolol Derivatives as Anticancer Agents for NSCLC Using 3D-QSAR, Molecular Docking, MOLCAD and MM-GBSA Studies	5
Exploring DPP-IV inhibitors for diabetes treatment: A comprehensive study on molecular docking, molecular dynamics simulation, and in-vitro DPP-IV assay	5
Identification of active compounds and therapeutic mechanisms of traditional Chinese medicine for periarthritis of shoulder for promoting blood circulation and removing stasis (PBRS): A network pharma	5
Molecular Modeling of some 1,3,4-Oxadiazole Derivatives as EGFR Inhibitors for the Treatment of Cancer	5
Efficacy and safety of PD-1/PD-L1 inhibitors for relapsed/metastatic nasopharyngeal carcinoma: A systematic review and meta-analysis	5
Lycopene-Loaded Solid Lipid Nanoparticles: Preparation, Characterization, ROS-Scavenging, and In vitro Anti-Melanogenesis Evaluations	4
Ethosomes: Novel Vesicular Carriers for Effective Transdermal Delivery of Natural Therapeutics	4
Molecular Docking, Dynamics Simulation, and Physicochemical Analysis of Some Phytochemicals as Antiplatelet Agents	4
Nanotechnology-Based Approaches for Nose-to-Brain Drug Delivery in Neurodegenerative Diseases	4
Naphthoquinone-triazole hybrids as anti-diabetic agents: An exploration of in silico and in vitro α-glucosidase and α-amylase inhibition	4
Synthesis, Characterization and Screening of Some Novel 2-Methyl-N'- [(Z)-Substituted-Phenyl ethylidene] Imidazo [1, 2-a] Pyridine-3-Carbohy drazide Derivatives as DPP-IV Inhibitors for the Treatment	4
Conjugation of Mycophenolic Acid with Dextran: A Potential Strategy for Colon-Targeted Delivery for Mitigation of Inflamed Colon in Ulcerative Colitis	4
Phytosome: An Effective Transdermal Drug Delivery System for Phytoconstituents	4
Bdellovibrio bacteriovorus Therapy, an Emerging Alternative to Antibiotics	4
Demonstration of Interaction between Carbapenem Group Antibiotics and Different Immunosuppressant Drugs by Molecular Docking	4
Novel 2-pyridone Analogs with Anti-cancer Activity: Synthesis, In silico, and In vitro Evaluation	4
Network pharmacology, molecular docking, and experimental validation of dihydromyricetin attenuating LPS-induced acute lung injury by promoting FGFR1	4
In silico De Novo Discovery of Novel Target-specific Drug-like Bidentate Inhibitors of PTP 1B	4
Polygenic Regulation by Flos Daturae in the Treatment of Breast Cancer: A Study based on Network Pharmacology and Bioinformatics	4
Development and evaluation of optimized molecularly imprinted polymer (MIP) for targeted drug delivery of 5-Fluorouracil	4
Based on the Network Pharmacology to Analyze the Effect of Chuanxiong in Improving Diabetic Nephropathy	4
Towards Further Understanding the Role of Curcumin in Wound Healing: A Systems Biology Approach	4
Quantum Mechanics Modeling of Oxetanes as Epoxide Hydrolase Substrates	4
An Ultrasound-assisted Three Component Protocol for the Regio and Stereo-selective Synthesis of Some Novel Dispiroheterocycles and Their Biological Evaluation as Anti-inflammatory, Anti-obesity Agents	4
Discovery of MAO-A Inhibitors as Antidepressant Based on Virtual Screening	4
Rational Design and Synthesis of Novel Benzimidazole Derivatives as Potential β-Glucosidase Inhibitors	4
Network Pharmacological Study of the Active Ingredient of Panax Notoginseng Saponins for the Treatment of Lung Cancer by Inhibiting AKR1C3	4
Pharmacophore Based Design of Probable FGFR-1 Inhibitors from the 3D Crystal Structure of Infigratinib - A Drug Used in the Treatment of Cholangiocarcinomas	4
Molecular Docking Studies for Protein-Targeted Drug Development in SARS-CoV-2	3
Novel 5-fluoro-6-(4-(2-fluorophenyl)piperazin-1-yl)-2-(4-(4-methylpiperazin- 1-yl)phenyl)-1H-benzo[d]imidazole Derivatives as Promising Urease Inhibitors	3
Virtual Screening of Telaprevir and Danoprevir Derivatives for Hepatitis C Virus NS3/4A Protease Inhibitors	3
Synthesis and Anticancer Activities of Novel Bis-chalcones Incorporating the 1,3-diphenyl-1H-pyrazole Moiety: In Silico and In Vitro Studies	3
Bioactive Natural Leads and Traditional Herbal Plants in the Management of Inflammatory Bowel Diseases: A Brief Review	3
Perillaldehyde Building Block’s Derivatives: Targeted Bioactivities and Molecular Docking	3
Identification of Potential Inhibitors for Severe Acute Respiratory Syndrome-related Coronavirus 2 (SARS-CoV-2) Angiotensin-converting Enzyme 2 and the Main Protease from Anatolian Traditional Plants	3
Molecular Modelling Simulations and Inhibitory Effects of Naturally Derived Flavonoids Targeting Platelet-Activating Factor Receptor (PAFR)	3
Synthesis and Biological Activity of 2-pyridone Derivatives: A Mini Review	3
Metformin Sensitizes Cisplatin-induced Apoptosis Through Regulating Nucleotide Excision Repair Pathway In Cisplatin-resistant Human Lung Cancer Cells	3
The Importance of Salicylic Acid, Humic Acid and Fulvic Acid on Crop Production	3
An appraisal on biomolecular imaging in diagnosis of neurological disorders and innovation in clinical research	3
Computational Design of a Novel Inhibitor against COVID	3
Exploring the antimicrobial and biofilm inhibitory potential of Citrus limetta peel essential oil against multidrug-resistant Shigella: In vitro and in silico insights	3
The effects of hydrogen-rich water on gut microbiota and related health outcomes: A systematic review	3
Exploring the Antitumor Potential of New Indazole-indolizines Designed by Molecular Hybridization	3
Mesalamine may be a Plausible Therapeutic Agent for the Management of Diabetic Wounds: A Computational Approach	3

Synthesis, Characterization, Antibacterial Evaluation, and Enzyme Inhibition Activity of a Novel Nitrogen-containing Heterocyclic Sulfonamide	3
Synthesized Drug from Medicinal Plant phytochemicals Effectively Targets ECM1 Gene Mutations in Ulcerative Colitis	3
Potential Drug Targets Identification Against Clostridioides Difficile (CD) and Characterization of Indispensable Proteins by a Subtractive Genomics Approach Followed by Virtual Screening	3
Synthesis, Computational Study, and Anticonvulsant Activity of Newly Synthesized 2-aminobenzothiazole Derivatives	3
Synthesis and Biological Evaluation of Novel Oxazolidinone Derivatives Containing Dithiocarbamate Moiety as Antibacterial Agents	3
Recent Advances in Therapeutic Strategies against Hydatid Cysts using Nanomaterials: A Systematic Review	3
Design and Screening of KLHL22 Inhibitors by Homology Modeling, Molecular Docking, and Molecular Dynamics Simulation	3
Optimizing therapeutic strategies for hypertensive disorders of pregnancy through multi-omics integration and network pharmacology	3
Exploring the mechanism of action of tolvaptan in the treatment of cor pulmonale pulmonary hypertension using network pharmacology and animal-based experiments	3
A Review of the Azasteroid-type 5-alpha Reductase Inhibitors for the Management of Benign Prostatic Hyperplasia	3
One-Pot Green Synthesis of Novel Thiazolepyridine Conjugated Benzamides as Anti-Bacterial Agents and their Molecular Modelling Studies	3
A Novel Drug Delivery Platform Against Bacterial Resistance: Synthesis and Characterization of Ciprofloxacin-loaded MCM-41 Mesoporous Silica Nanoparticle	3
Mechanism of Pyroptosis in Postoperative Cognitive Dysfunction Rats and α7-nicotinic Receptor Agonist Regulating NLRP3 Inflammasome Activation	3
Multi-modal investigation of doxorubicin-induced osteoporosis: Network toxicology, machine learning, and imaging techniques	3
Natural Antioxidants of the Underutilized and Neglected Plant Species of Asia and South America	3
Synthesis and Anti-proliferative, Tyrosine Kinases Inhibitions of New Xanthene Derivatives and their Morphological Studies	3
Garcinol: An emerging epigenetic modifier with versatile anticancer properties	3
In-silico Studies, Synthesis, and Evaluation of Anti-inflammatory Activity of Novel Pyrimidine Scaffold	3
Exploration of the potential molecular mechanism of magnolol in colorectal cancer treatment based on network pharmacology and molecular docking	3
Diversely Functionalized Pyridine Ring-fused Heterocycles and their Anticancer Properties	3
The Most Important Medicinal Herbs and Plants in Traditional Chinese and Iranian Medicinal Sciences with Antioxidant Activities	3
Identification of Novel CDK 4/6 Inhibitors by High-throughput Virtual Screening	3
Role of a Dual Inhibitor of RAS/PI3K/AKT and RAS/RAF/MEK on Post-surgical Adhesion Band Formation	3
Effects of Compound in Hedyotis diffusa Willd against Acute Myeloid Leukemia: An In Silico and In Vitro Study	3
Structure-guided Development of Novel Benzothiophene Derivatives as PLK1-PBD Inhibitors	3
Exploring the mechanism of Grifolin in inhibiting the malignant progression of colon cancer cells mediated by the PDGFRB/PI3K/AKT signaling pathway based on bioinformatics analysis and network pharmac	3
Imperatorin remits malignant progression of endometrial cancer by silencing E2F1/SLC3A2	3
Palladium (II)-N-heterocyclic Carbene Complexes: Synthesis, Molecular Docking, UV-Vis Absorption and Enzyme Inhibition	3
Investigating the mechanism of curcumin against LUAD malignant progression and macrophage M2 polarization based on network pharmacology, bioinformatics, and molecular docking	3
The Hepatoprotective Effect of a Newly Synthesized 5-mercapto-1,2,4-triazole Derivative based on Nalidixic Acid against CCl4 induced Oxidative Stress in Mice	3
Virtual Screening, Molecular Docking, and Physiochemical Analysis of Novel 1,3-diphenyl-2-propene-1-one as Dual COX-2/5-LOX Inhibitors	3
Preparation of Metformin Biodegradable Polymeric Microparticles by O/O Emulsion Solvent Evaporation: A 32 Full Factorial Design Approach	3
Synthesis, Characterization, and Evaluation of Antioxidant Activities of 2-(1-(Substituted phenyl)ethylidene)-1-(4,6-dimethylpyrimidin-2-yl)hydrazines	3
Thymoquinone suppresses cell growth and induces ferroptosis in renal cell carcinoma by reducing SERPINH1 expression	3
Exploration of the mechanism of quercetin against GDM based on network pharmacology and molecular docking	3
CD44 as the Target Site for Hyaluronic Acid in Favor of Colitis Management	3
Formulation and Characterization Studies of Paclitaxel Incorporated Kollidon® SR and Chitosan Nanoparticles: An In vitro Evaluation for Potential Use for Colorectal Cancer Treatment	3
Asiaticoside Enhances the Osteoblast Potential of LPS-induced Periodontal Ligament Stem Cells through TLR4/NF-κB Pathway	3
The Synthesis and Pharmacological Activity of Ursolic Acid Derivatives Modified at C-28 and C-3 Sites	3
Molecular Dynamics Simulations and Binding Free Energy Calculations to Discover New Insights into NLRP3 Inhibitors	2
Pyrazolone Derivatives: Synthetic Chemistry, Exploring Pharmacological Activity - A Mini Review	2
Medicinal Plants and Natural Products to Treat Obesity through Inhibiting Pancreatic Lipase: A Review (2020-2022)	2
Boesenbergia Pandurata as an Anti-Breast Cancer Agent: Molecular Docking and ADMET Study	2
Amidoximes and their Cyclized Analogue Oxadiazoles as New Frontiers in Chemical Biology: Mini Review	2
LC-MS/MS of Dexamethasone in Rabbit Vitreous Liquid Delivered through Novel Self-nanoemulsifying Drug Delivery Systems	2
Pharmacoinformatics-based identification of dual inhibitors of leishmanial DHFR and PTR1 enzymes	2
Research Progress of Vitamin K2 Related Signal Pathways: A Literature Review	2
A Linear and Nonlinear QSAR Analysis of Benzimidazole Derivative XY123 in Prostate Cancer Treatment	2
Coronavirus Inhibitory Activity of Tamarind Indica	2
Discovering Drug Candidates for Charcot Marie Tooth Disease Type-2	2
AI-driven target discovery and clinical development of candidate drugs for idiopathic pulmonary fibrosis: A review	2
Dynamic Comparison of Binding Pocket of Berberine Protein Crystals	2
Nanoemulgel-based delivery of 3-O-Acetyl-11-Keto-β-Boswellic Acid and basil oil for enhanced transdermal efficacy: In vitro anti-inflammatory and antioxidant assessment	2
3D-QSAR and Molecular Docking Studies of Pyrimidine-based EGFR Inhibitors	2
Structure-guided target prioritization of heterocyclic carboxamides for hyperlipidemia and obesity via cheminformatics, network biology, and docking studies	2
In vitro Antibacterial Activity of Dye Compounds	2
Synthesis of Ethyl Methyl 4-aryl-1,4-dihydropyridine-3,5-dicarboxylates as Potential Calcium Channel Blockers for Hypertension	2
Synthesis and Preliminary Biological Evaluation of New Phthalazinone Derivatives with PARP-1 and Cholinesterase Inhibitory Activities	2
Aptamers-based Strategies for the Treatment of Microbial Infections	2
Molecular Modeling Study for the Evaluation of Natural Compounds as Potential Lanosterol 14α-Demethylase Inhibitors	2
In vitro and in silico analysis reveal the potential mechanisms of Liu-Wei-Di-Huang-Wan formula for tinnitus treatment	2
Design and Characterisation of Rosuvastatin Calcium Nanosuspension Loaded Transdermal Patch	2
Insights into Evolutionary and Conservancy Analytics on Human Insulin Receptor Proteins	2
Identification of Withanolide G as a Potential Inhibitor of Rho-associated Kinase-2 Catalytic Domain to Confer Neuroprotection in Ischemic Stroke	2
Conducting 2D and 3D QSAR Analyses and Molecular Docking Studies of Analogues of 2-(1-(1,3,4-thiadiazol-2-yl)piperidin-4-yl)ethan-1-ol with the Aim of Identifying Promising Drug Candidates for Targeti	2
Electrochemical Modification of Metronidazole and its Application as Antibacterial and Potential Drug Agent	2
Berberine suppresses the malignant progression of ovarian cancer by downregulating HSP90AA1 expression	2
Chemical Composition, In vitro and In silico Evaluation of Essential Oil Extracted from Mentha Piperita L. for Lung Cancer	2
In silico Identification of Fructose-1,6-biphosphatase Inhibitory Potentials of Xanthones Isolated from African Medicinal Plants: An Integrated Computational Approach	2
Gm15886-Hipk1 Signaling Pathway Plays Important Roles in the Pathogenesis of Bronchopulmonary Dysplasia Mice	2
Remifentanil and Propofol Co-loaded Nanoemulsion: Formulation Development and In vivo Pharmacodynamic Evaluation	2
Network Pharmacological Analysis and Experimental Validation of Anti-lung Cancer Effect of Echinacea Purpurea	2
Anti-evolution Drugs: A New Paradigm to Combat Drug Resistance	2
Design, Synthesis, Biological Evaluation, Molecular Docking, and Molecular Dynamics Simulation Studies of Fmoc-L-Lysine Carboxamides as Promising Cytotoxic Agents	2
Acenaphthotriazine Thio-triazole Derivatives as Anti-cancer Agents Triggering Cell Cycle Arrest in Breast Cancer Cells	2
The mechanism of Peilian Ephehuang Prescription in the treatment of simple obesity based on network pharmacology and molecular docking technology	2
Attacking the SARS-CoV-2 Replication Machinery with the Pathogen Box’s Molecules	2
A Rational Approach to Anticancer Drug Design: 2D and 3D- QSAR, Molecular Docking and Prediction of ADME Properties using Silico Studies of Thymidine Phosphorylase Inhibitors	2
Anti-cancer Potential of Pleurotus Mushroom: Detailed Insight on the Potential Bioactive Molecules, In vitro-In vivo Studies, and Formulation	2
Tirzepatide: A First-in-class Twincretin for the Management of Type 2 Diabetes	2
Synthesis, Computational Study of β-lactam Derivatives Bearing Quinazoline Schiff Bases as Anthelmintics	2
In Silico and In Vitro Screening of Novel Pyridazine Analogs as Muscle Relaxant Agent on Acetylcholine Muscarinic Receptor	2
Targeting Angiotensin-converting Enzyme Inhibitor via Enalapril Reduces Postsurgical Adhesion Band Formation	2
Ginsenoside Rh3 suppresses cell proliferation, metastasis, and oxidative stress of colorectal cancer via targeting HSP90AA1	2
Virtual Screening of Novel Phytocompound(s) with Potential to Combat Mycobacterium tuberculosis Infection	2
Neuroprotective Potential of Polydatin in Combating Parkinson’s Disease through the Inhibition of Monoamine Oxidase-B and Catechol-o-Methyl Transferase	2
1,2,4 Triazoles and 1,2,4 Oxadiazoles Scaffold as SGLT2 Inhibitors: Molecular Docking and ADMET Studies	2
In Silico, In Vitro and In Vivo Assessment of Acetylcholinesterase Inhibitory Activity of Theobromine Derivatives Containing an Arylpiperazine Fragment	2
Structural classification of HDAC inhibitors and cancer treatment prospects: A review	2
Mechanism of American Ginseng Against Type 2 Diabetes Mellitus Based on Network Pharmacology & Molecular Docking	2
QSAR Studies on a Series of Pyrazole Azabicyclo [3.2.1] Octane Sulfonamides N-acylethanolamine-hydrolyzing Acid Amidase Inhibitors	2
QSAR Model Study of 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole of Cystic- brosis-transmembrane Conductance-regulator Gene Potentiators	2
Stilbene-based Derivatives as Potential Inhibitors of Bcl-2 Antiapoptotic Proteins: A Molecular Docking Study and ADMET Prediction	2
Shugan Jiangzhi Decoction Alleviates Nonalcoholic Fatty Liver Disease (NAFLD) via Regulating AMPK/PPAR Signaling Pathway	2
Uncovering the Biological Applications of Cinnamic Acid Derivatives: A Patent Review	2