OOIR: Observatory of International Research

Papers

(The median citation count of Current Organic Synthesis is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Ultrasound-assisted and Efficient Multicomponent Synthesis of 4H-Pyran Derivatives Catalyzed by LiOH.H₂O in Water	47
Efficient Formylation of Alcohols Using a Core-Shell Magnetic Nanocomposite Via Vilsmeier-Haack Complex Formation	27
Omega Indices of Strong and Lexicographic Products of Graphs	26
Selenocyclization by Formation of Carbon-nitrogen Bonds	22
Efficient Generation of Specific Counting Polynomials and their Subsequent Indices of Complex Boric Acid Structure	21
Beyond 1,2,3-triazoles: Formation and Applications of Ketemines Derived from Copper Catalyzed Azide Alkyne Cycloaddition	21
Research Progress on the Application of Nanocellulose in Glucose Sensing	20
Efficient Synthetic Access to Novel Indolo[2,3-b]Quinoxaline-based Heterocycles	19
Synthesis, Anti-acetylcholinesterase Evaluation, Molecular Docking and Molecular Dynamics Simulation of Novel Psoralen Derivatives	19
Facile Synthetic Protocols for the Preparation of New Impurities in Pemetrexed Disodium Heptahydrate as an Anti-cancer Drug	19
GOQDs and GOQDs-NS-doped Carbocatalysts: A Concise Study on Production and Use in One-pot Green MCRs	19
A Review on Novel Synthesis Approaches and Biological Activities of 1,2,4- Oxadiazole and 1,3,4-Oxadiazole Tailored Compounds	19
Synthesis and Characterization of 3-S-impurities in Timolol Maleate	17
Synthesis, Reaction and Biological Activity of Thiazoles	17
Towards the Synthesis of a Heterocyclic Analogue of Natural Cyclooligopeptide with Improved Bio-properties	16
Design, Synthesis, QSAR Studies, and Molecular Modeling of Some Novel Bis Methyl 2-[3-(benzo[d]thiazol-2-yl)-2-terephthaloyl-bis-4-oxo-thiazolidin- 5-ylidene]acetates and Screening of their Antioxidan	16
Synthesis of Isatin Derivatives Exhibiting Antibacterial, Antifungal and Cytotoxic Activities	15
Antiphytopathogenic Effects and the Preliminary Mechanisms of 5-nitro-8-hydroxyquinoline Derivatives	15
One-pot Multicomponent Reaction: An Efficient Synthesis of 4-(Het)Aryl-substituted Pyrazolo-quinolinones	14
Diselenides and Selenocyanates as Versatile Precursors for the Synthesis of Pharmaceutically Relevant Compounds	14
Synthetic Strategies for Quinoline Based Derivatives as Potential Bioactive Heterocycles	14
Heteroaromatization of Coumarin Part II: Synthesis, Reactions, and Antimicrobial Activities of Novel Pyrido[2,3-d]pyrimidine Derivatives	13
Changes in Germination Parameters, Growth and Development of Three Cultivars of Corn Seedlings under Various Aqueous Extracts of Mallow	13
An Insight on the Prospect of Quinazoline and Quinazolinone Derivatives as Anti-tubercular Agents	13
Combinatorial Study of Organic Structures	12

Novel Penicillin Derivatives Against Selected Multiple-drug Resistant Bacterial Strains: Design, Synthesis, Structural Analysis, In Silico and In Vitro Studies	12
Pyrazoline and Analogs: Substrate-based Synthetic Strategies	11
Diverse Synthetic Approaches and Biological Activities of Lucrative Pyrimidine- Triazine Hybrid Derivatives: A Review	11
Organocatalytic Synthesis of (Hetero)arylidene Malononitriles Using a More Sustainable, Greener, and Scalable Strategy	11
Recent Advancement in Multicomponent Synthesis of Fused Coumarin Derivatives	11
Asymmetric Organocatalytic Syntheses of Bioactive Compounds	11
Special Issue on Exploring the Role of Chemical Graph Theory in Advancing Current Organic Synthesis-Part I	10
Incorporation of Protecting Groups in Organic Chemistry: A Mini-Review	10
Transition Metals Catalyzed Direct C-H Chalcogenation of Arenes and Heteroarenes	10
Synthesis, Antimicrobial and Antioxidant Activity of Some New Pyrazolines Containing Azo Linkages	10
Omega Invariant of Complement Graphs and Nordhaus-gaddum Type Results	10
Advances in Chiral Pesticides	10
Arylidenemalononitriles as Versatile Synthons in Heterocyclic Synthesis	9
Green Approach Toward Triazole Forming Reactions for Developing Anticancer Drugs	9
Recent Advancements in the Synthesis of α-fluoroalkylated Azine-derived Heterocycles through Direct Fluorination	9
Solvent-free MALI-MGRE Procedure for Synthesizing 1,4-thiazolidin-4- one MALI (Mercaptoacetic Acid Looking Imine) MGRE (Mechanical Grinding Reaction Equipment)	8
A New Way to the Synthesis of Tricyclic Compounds via Nitrone 1,3- cycloaddition Dipolar Reaction	8
Anti-inflammatory and Antimicrobial Potential of 1, 3, 4-oxadiazoles and its Derivatives: A Review	8
A Review of the Synthesis of Oxazoline Derivatives	8
Computing the Energy of Certain Graphs based on Vertex Status	8
Synthesis and Characterization of Polyacetyltetrazine from Hydrazonoyl via [3+3] Self-Polycycloaddition	8
Synthesis by Microwave Irradiation, Molecular Structural Analysis and Trypanocidal Activity of Novel Pyrazole-tetrahydropyrimidine Derivatives	8
A Brief Review on Recent Developments in Diels-alder Reactions	8
Scale-up of Sodium Persulfate Mediated, Nitroxide Catalyzed Oxidative Functionalization Reactions	7
Synthesis and Cytotoxic Activity of Quinazoline-benzofuran Conjugates	7
Copper Supported Imidazolylpyridine Modified SPION as an Efficient Catalyst for Eco-friendly, One-pot and Green Synthesis of Novel (3- Cyanothiophen-2-yl)-N-(arylsulfonyl)acetimidamide Derivatives	7
Recent Developments in Multi-component Synthesis of Lawsone Derivatives	6
Green Synthesis and Anticancer Activity of New Bis-imidazole-thiazole Hybrids Targeting Hepatocellular Carcinoma	6
Co₂(CO)₈ as a CO-source for Pd-catalyzed Carbonylations: An Update	6
Recent Progress on Photonic Cellulose Nanocrystal Films for Sensing Applications	6
Synthesis and Molecular Docking Study of Some New Thiazole-coumarin Molecular Hybrids as Antibacterial Agents	6
Recent Updates on Synthesis, Biological Activity, and Structure-activity Relationship of 1,3,4-Oxadiazole-quinoline Hybrids: A Review	6
Synthesis of Misoprostol, and Intramolecular Isomerization of A-Type Misoprostol into B-Type Misoprostol using 1, 8-Diazabicyclo [5.4.0] undec- 7-ene (DBU)	5
Synthesis, Characterization, DPPH Radical Scavenging, Urease Enzyme Inhibition, Molecular Docking Simulation, and DFT Analysis of Imine Derivatives of 4-formylpyridine with Selective Detection of Cu+2	5
A Potential Fungicide against Pseudoperonospora cubensis: Design, Synthesis and 3D-QSAR of New Pyrazole-5-carboxamide Derivatives	5
Research Progress of Isoxazoline Insecticides	5
Mechanochemical Promoted Heterocycles: A Solvent-free Route to Triazole Carbohydrates as Glycogen Phosphorylase Inhibitors	5
Recent Discovery of Triazine Derivatives as Protease Inhibitors for the Treatment of Coronavirus-19 (COVID-19)	5
Advances in the Total Synthesis of Pharmacologically Important Fused Indolizidine Alkaloids: Securinine, Gephyrotoxin and Lepadiformine	5
Acknowledgement To Reviewers	5
New Relations between Zagreb Indices and Omega Invariant	5
Synthesis of Phentermine and its Derivatives	5
Catalytic One-pot Solvent Free Synthesis, Biological Activity, and Docking Study of New Series of 1, 3-thiazolidine-4-one Derivatives Derived from 2- (P-tolyl) Benzoxazol-5-amine	5
Neighbourhood Sum-Based Structural Analysis for Sodalite System	5
Connection-Based Zagreb Indices of Polycyclic Aromatic Hydrocarbons Structures	5
Cyanamide-Based Cyclization Reactions for Nitrogen-Containing Heterocycles Synthesis	5
Metal- and Photocatalyst-Free Sulfonylcyanation of [1.1.1]Propellane with Sulfonyl Cyanide	5
Zagreb Topological Properties of Hexa Organic Molecular Structures	5
Degree Descriptors and Graph Entropy Quantities of Zeolite ACO	5
WITHDRAWN: Synthesis of 1-Halophenyl-pyrazolophthalazine Derivatives and Evaluation of their Antimicrobial Activity	4

Recent Progress in Chemical Modification of the Natural Polysaccharide Guar Gum	4
Synthesis and Characterization of Novel Polythiadiazoles from Bis-hydrazonoyl Dichlorides and Bis-(methyl-2-arylidene Hydrazone Carbodithioates)	4
Synthesis and Characterization of a Julolidine-based Electro-optic Molecular Glass	4
Ag-catalyzed Multicomponent Synthesis of Heterocyclic Compounds: A Review	4
The Emerging Role of Polyethylene Glycol-Water (PEG-H₂O) as the Benign Mixed Solvent System in Organic Synthesis	4
Barbiturates: A Review of Synthesis and Antimicrobial Research Progress	4
Recent Advances in the Green Synthesis of Heterocycles: From Building Blocks to Biologically Active Compounds	4
Comparison Between Solid Catalysis and Electrochemical Catalysis in the Synthesis of Methyl Carbamate via Hofmann Rearrangement	4
Synthesis and Biological Evaluation of Paclitaxel-aminoguanidine Conjugates for Suppressing Breast Cancer	4
A Pharmacological Overview and Recent Patent of Triazine Scaffold in Drug Development: A Review	4
Multidimensional Uses of Bitter Melon (Momordica charantia L.) Considering the Important Functions of its Chemical Components	4
A Review on the Role of Transition Metals in Selenylation Reactions	3
Synthesis oftransN-Substituted Pyrrolidine Derivatives Bearing 1,2,4- triazole Ring	3
Aza-BODIPY-based Fluorescent and Colorimetric Sensors and Probes	3
Mathematical Modeling and Estimation of Physicochemical Properties of Non-Steroidal Anti-Inflammatory Drugs via an Innovative Approach of Biquadratic Reg	3
Aminoimidazo[1,2-a]pyridine Bearing Different Pyrazole Moieties as the Structural Scaffold for the Development of BACE1 Inhibitor; Synthesis, Structural Characterization, in vitro and in silico Studie	3
Isocyanide-based Multicomponent Reactions (IMCRs) in Water or Aqueous Biphasic Systems	3
Synthesis, Characterization and Biological Activity of Benzimidazoleacrylonitrile Derivatives	3
An Efficient Protocol for the Synthesis of new Camphor Pyrimidine and Camphor Thiazole Derivatives using Conventional and Microwave Irradiation Techniques and In vitro Evaluation as Potential A	3
Investigation of the Dyeing Ability of Some Reactive Triazine Azo Dyes Containing Pyrazole Fragment	3
Design, Synthesis and Anticancer Evaluation of New 1-allyl-4-oxo-6-(3,4,5- trimethoxyphenyl)-1,4-dihydropyrimidine-5-carbonitrile Bearing Pyrazole Moieties	3
Synthesis of 2,5-Dithia-bicyclo[4.1.1]octanes	3
Design, Synthesis, and Biological Assessment of Bis-thiazole Derivatives as Promising Anticancer Agents with Molecular Docking Insights	3
Coupling of Thiols and Aryl Halides Mediated by Dicyclohexano-18- crown-6 and Potassium Carbonate	3
Green Synthesis of Mono, Bis and Tris Aminobenzochromenes and Benzopyranochromenes using Fe3O4@Sio2@ Vanillin/Vitamin B1 Nanoparticles: A New, Mild, Simple and Effective Bronsted Acid Catalyst for the	3
Recent Advances in Organoselenium Catalysis	3
Innovative Green Synthesis and Multifunctional Applications of Pyrimidopyrimidine Derivatives	3
Advance Screening of Bis-azetidinone Derivatives: Synthesis, Spectroscopy, Antioxidant and Antimicrobial Analysis with Molecular Docking Assessment	3
Thematic Issue: Emerging Aspects of Click Chemistry	3
Imidazole Hydrochloride Promoted Synthesis of Nitriles from Aldehydes	3
An Exhaustive Compilation on the Synthesis of Heterocycles Pendant on the Fatty Acid Alkyl Chains	3
High-component Reactions (HCRs): An Overview of MCRs Containing Seven or More Components as Versatile Tools in Organic Synthesis	3
Synthesis, Application, and Antibacterial Activity of New Direct Dyes based on Chromene Derivatives	3
Free Salt Dyeing by Treatment of Cotton Fabric Using Carboxyethyl Chitosan and Synthesized Direct Dyes to Enhance Dyeing Properties and Antibacterial Activity	3
A Study on Synthesis of Chalcone Derived -5- Membered Isoxazoline and Isoxazole Scaffolds	2
Design and Facile Synthesis of Spiro-s-tetrazine Derivatives of 2,4- diphenyl-3-azabicyclo[3.3.1]nonane-9-one	2
Reactions and Biological Activities of Hydrazonoyl Halides	2
Diverse Pharmacological Potential of different Substituted Pyrazole Derivatives	2
Tetra-azolium Salts Induce Significant Cytotoxicity in Human Colon Cancer Cells In vitro	2
Recent Progress in Free Radical Transformations of Allenamides	2
The Conjugation of Chlorambucil with 4-Phenylbutanoic Acid and Valproic Acid respectively for Enhancing Anti-tumor Activity	2
Green Ugi-3CR Method for the Synthesis of α-Aminoamides in Water Using SLS	2
Recent Progress on Synthesis of Functionalized 1,5-Disubstituted Triazoles	2
Revisiting the Synthesis of Betti Bases: Facile, One-pot, and Efficient Synthesis of Betti Bases Promoted by FeCl3•6H2O	2
Reaction Optimization of Strontium Perchlorate Catalyzed Novel Protocol for Stereoselective Synthesis of Dihydropyrimidinones	2
Design, Synthesis, Molecular Docking, and Antimicrobial Evaluation of Novel 1,3-thiazolidine-4-one Derivatives Incorporating Pyridine Scaffold	2
Intramolecular Click Cycloaddition Reactions: Synthesis of 1,2,3-Triazoles	2
Colorimetric and Fluorimetric Chemosensors for Detection of Anions, Cations, pH and Small Molecules	2
Recent Advancement in the One-pot Synthesis of the Tri-substituted Methanes (TRSMs) and their Biological Applications	2
A Convenient one-pot Approach to the Synthesis of Novel Benzimidazole-Indole Molecular Hybrids as Benzazacamalexin Related Analogues	2
Synthesis and Development of Suitable Method for New Thiadiazoles using Hydrazonoyl Halides	2
Practical Synthesis of 1,4-Dihydropyridines on Heterogeneous Sulfonicmodified Silica (SBA-15-SO3H) Catalyst Under Mild Condition	2
Polyethylene Glycol-400 Prompted an Efficient Synthesis of Thienyl Pyrazolo[ 1,5‐a] Pyrimidines as Microbial Inhibitors	2
Chitosan-based Nano/Biomaterials in Bone Tissue Engineering and Regenerative Medicine: Recent Progress and Advances	2
Pyrene Appendant Triazole-based Chemosensors for Sensing Applications	2
Computational and Molecular Docking Studies of New Benzene Sulfonamide Drugs with Anticancer and Antioxidant Effects	2
A Review on Modern Approaches to Benzimidazole Synthesis	2
Exploring Neighborhood Topological Descriptors for Quantitative Structure-property Relationship (QSPR) Analysis and Entropy Measures of Some Anti-cancer Drugs	2
Forgotten Topological and Wiener Indices of Prime Ideal Sum Graph of ℤn	2
Sustainable Catalyst-free N-formylation using CO2 as a Carbon Source	2
Comprehensive Account on the Synthesis of (-)-Balanol and its Analogues	2
Green Recipes for Pyrimidine	2
Supported Ionic Liquids and their Applications in Organic Transformations	2
A Facile Total Synthesis of Kilogram-Scale Production of SKLB1039: A Novel and Selective Hexahydroisoquinolin-Containing EZH2 Inhibitor	2
Synthesis of 5-(trifluoroacetyl)imidazoles from Bromoenones and Benzimidamides via Aza-Michael Initiated Ring Closure Reaction	2
A Comprehensive Review on Synthetic Approaches and Antibacterial Activity Studies of 1,2,4-Triazole Derivatives over the Past Sixteen Years (2009-Present)	2