Current Neuropharmacology

Article	Citations
Effects of β -caryophyllene, A Dietary Cannabinoid, in Animal Models of Drug Addiction	120
Three Decades of Valproate: A Current Model for Studying Autism Spectrum Disorder	93
Local and Remote Chemogenetic Suppression of Hippocampal Seizures in Rats	92
Neuroprotective Role of Quercetin against Alpha-Synuclein-Associated Hallmarks in Parkinson’s Disease	84
Modulating Ferroptosis: A Novel Approach to Promote Neural Repair in Brain Injury	83
Comorbidities in Youth with Bipolar Disorder: Clinical Features and Pharmacological Management	81
Long-Term Implicit Epigenetic Stress Information in the Enteric Nervous System and its Contribution to Developing and Perpetuating IBS	79
Role of Glycerophospholipid Metabolism in Epilepsy	74
The Effects of Drugs used for the Treatment of Attention Deficit Hyperactivity Disorder (ADHD) on Pregnancy Outcome and Breast-feeding: A Critical Review	69
Childhood Trauma and Self-harm in Youths with Bipolar Disorders	66
The Role of Natural Products in Treatment of Depressive Disorder	60
Redox Modulation of Meniere Disease by Coriolus versicolor Treatment, a Nutritional Mushroom Approach with Neuroprotective Potential	60
Early Family Intervention for Youth at Risk for Bipolar Disorder: Psychosocial and Neural Mediators of Outcome	57
Neurocognitive Correlates of Cerebellar Volumetric Alterations in Youth with Pediatric Bipolar Spectrum Disorders and Bipolar Offspring	56
Effect of Repetitive Transcranial Magnetic Stimulation in Inducing Weight Loss in Patients with Chronic Schizophrenia: A Randomized, Double-Blind Controlled 4-Week Study	56
siRNA Therapeutics: Future Promise for Neurodegenerative Diseases	50
Advances in the Pharmacological and Non-pharmacological Management of Non-motor Symptoms in Parkinson’s Disease: An Update Since 2017	49
Meet the Editorial Board Member	47
Mimicking Extracellular Matrix via Engineered Nanostructured Biomaterials for Neural Repair	47
Thematic Selection: Stress and Stress-related Disorders Neurobiology & Translational Aspects of Stress-related Disorders (Part 3)	46
Sex-Specific Association between Antioxidant Defense System and Therapeutic Response to Risperidone in Schizophrenia: A Prospective Longitudinal Study	43
Deciphering the Causality between Gut Microbiota Dysbiosis and Poisoning by Narcotics and Psychodysleptics: A Mendelian Randomization Analysis	43
Unveiling the Potential Neuroprotective Effect of Bioactive Compounds from Plants with Sedative and Mood-Modulating Properties: Innovative Approaches for the Prevention of Alzheimer's and Parkinson's	42
Effects of Deep Brain Stimulation on Sleep-Wake Disturbances in Patients with Parkinson's Disease: A Narrative Review	41
Adherence to, and Persistence of, Antidepressant Therapy in Patients with Major Depressive Disorder: Results from a Population-based Study in Italy	41

Perspective on the Relationship between GABAA Receptor Activity and the Apparent Potency of an Inhibitor	40
Pharmacological Strategies for Bipolar Disorders in Acute Phases and Chronic Management with a Special Focus on Lithium, Valproic Acid, and Atypical Antipsychotics	39
Linking Diabetes to Alzheimer’s Disease: Potential Roles of Glucose Metabolism and Alpha-Glucosidase	39
Nabiximols is Efficient as Add-On Treatment for Patients with Multiple Sclerosis Spasticity Refractory to Standard Treatment: A Systematic Review and Meta-Analysis of Randomised Clinical Trials	36
The Formyl Peptide Receptor 2 as a Target for Promotion of Resolution of Inflammation	36
Antiseizure Medications: Advancements, Challenges, and Prospects in Drug Development	35
OL-FS13 Alleviates Cerebral Ischemia-reperfusion Injury by Inhibiting miR-21-3p Expression	35
Myeloid-derived Suppressor Cells and Multiple Sclerosis	34
Antioxidants, Hormetic Nutrition, and Autism	34
Modulation of Gut-Brain Axis by Probiotics: A Promising Anti-depressant Approach	32
What is the Role of Lithium in Epilepsy?	32
Microglia-Astrocyte Crosstalk in Post-Stroke Neuroinflammation: Mechanisms and Therapeutic Strategies	31
Meet the Country Editor	30
Progression in Moyamoya Disease: Clinical Features, Neuroimaging Evaluation, and Treatment	30
Vortioxetine versus SSRI/SNRI with Pregabalin Augmentation in Treatment-Resistant Burning Mouth Syndrome: A Prospective Clinical Trial	29
New Insights of Early Brain Injury after Subarachnoid Hemorrhage: A Focus on the Caspase Family	29
Major Depression in Comorbidity with Substance use Disorders: Patients’ Features and Clinical-Neurobiological Rationale of Antidepressant Treatments	29
The Emerging Role of Quercetin in the Treatment of Chronic Pain	29
mGlu3 Metabotropic Glutamate Receptors as a Target for the Treatment of Absence Epilepsy: Preclinical and Human Genetics Data	29
Fast Declining Prediction in Alzheimer’s Disease from Early Clinical Assessment	28
Paraquat and Parkinson’s Disease: The Molecular Crosstalk of Upstream Signal Transduction Pathways Leading to Apoptosis	28
Meet the Editorial Board Member	28
Gut Microbiome in Alzheimer’s Disease: from Mice to Humans	28
Long-term Efficacy and Safety of Sodium Oxybate in Treating Alcohol Use Disorder: A Systematic Review and Meta-Analysis	27
Is Antipsychotic Drug Use During Pregnancy Associated with Increased Malformation Rates and Worsening of Maternal and Infant Outcomes? A Systematic Review	27
How to Optimize the Effectiveness and Safety of Parkinson’s Disease Therapy? – A Systematic Review of Drugs Interactions with Food and Dietary Supplements	27
Early Enteral Feeding Restores Neurofilament Light Chain Serum Levels in Preterm Newborns	27
Role of Microglia in Psychostimulant Addiction	26
Meet Our Editorial Board Member	26
Neuroinflammatory Signaling in the Pathogenesis of Alzheimer’s Disease	26
Toxic Effects of Methamphetamine on Perivascular Health: Co-morbid Effects of Stress and Alcohol Use Disorders	26
Aryl Hydrocarbon Receptor Establishes a Delicate Balance between the Level of the Trace Amine Tryptamine and Monoamine Oxidase Activity in the Brain and Periphery in Health and Conditions such as Neur	26
The Lymphatic System In The Brain Clearance Mechanisms - New Therapeutic Perspectives For Alzheimer's Disease	26
Drug Target to Alleviate Mitochondrial Dysfunctions in Alzheimer’s Disease: Recent Advances and Therapeutic Implications	26
Meet the Editorial Board Member	26
The Role of Epigenetics in the Pathogenesis and Potential Treatment of Attention Deficit Hyperactivity Disorder	25
Alzheimer's Disease May Benefit from Olive Oil Polyphenols: A Systematic Review on Preclinical Evidence Supporting the Effect of Oleocanthal on Amyloid-β Load	25
Neuroinflammation: The Role of Anthocyanins as Neuroprotectants	25
Depression: An Insight into Heterocyclic and Cyclic Hydrocarbon Compounds Inspired from Natural Sources	24
A Review on Preclinical Models of Ischemic Stroke: Insights Into the Pathomechanisms and New Treatment Strategies	24
Depression and the Glutamate/GABA-Glutamine Cycle	23
The Role of Induced Pluripotent Stem Cells in the Treatment of Stroke	23
Targeting Gut Dysbiosis and Microbiome Metabolites for the Development of Therapeutic Modalities for Neurological Disorders	23
New Insights on Mechanisms and Therapeutic Targets of Cerebral Edema	22
Insights Into the Role of Copper in Neurodegenerative Diseases and the Therapeutic Potential of Natural Compounds	22
Dapsone, More than an Effective Neuro and Cytoprotective Drug	22
Pathomechanistic Networks of Motor System Injury in Amyotrophic Lateral Sclerosis	22
Serine Proteases and Chemokines in Neurotrauma: New Targets for Immune Modulating Therapeutics in Spinal Cord Injury	22
Meet the Section Editor	22
Sensory Reinforced Corticostriatal Plasticity	21

Bibliometric Analysis of Antipsychotic-induced Metabolic Disorder from 2006 to 2021 Based on WoSCC Database	21
Neonatal Arterial Ischaemic Stroke: Advances in Pathologic Neural Death, Diagnosis, Treatment, and Prognosis	21
Spatiomolecular Characterization of Dopamine D2 Receptors Cells in the Mouse External Globus Pallidus	21
MiR-142-3p is a Critical Modulator of TNF-mediated Neuronal Toxicity in Multiple Sclerosis	21
Bibliometric Analysis of the Research Status and Global Trends in Behavioral and Psychological Symptoms of Dementia in Alzheimer’s Disease from 2002 to 2022	21
From Phenomes to Genes: Phenotype-based Strategies in Rodents for Research on the Neurobiological and Genetic Bases of Psychiatric-relevant Traits	20
Emerging Roles of Microglia in Blood-Brain Barrier Integrity in Aging and Neurodegeneration	20
Titration of Pharmacological Responses in ICU Patients by Quantified EEG	20
The Modulatory Effects of Anesthetics and Analgesics on Neurophysiological Monitoring and Underlying Mechanisms	20
Prospective Investigation of Glutamate Levels and Percentage Gray Matter in the Medial Prefrontal Cortex in Females at Risk for Postpartum Depression	20
Targeting Estrogen Signaling in the Radiation-induced Neurodegeneration: A Possible Role of Phytoestrogens	20
Effects of Natural Products on Neuromuscular Junction	20
Advances in the Therapeutic Use of Non-Ergot Dopamine Agonists in the Treatment of Motor and Non-Motor Symptoms of Parkinson’s Disease	20
The Dual Role of Microglia in Multiple Sclerosis and its Implications for Diagnostics and Repair	20
Drug Delivery Nanosystems in Glioblastoma Multiforme Treatment: Current State of the Art	19
Sensorimotor Alterations Induced by Novel Fentanyl Analogs in Mice: Possible Impact on Human Driving Performances	19
Early Efficacy of Antipsychotic Medications at Week 2 Predicts Subsequent Responses at Week 6 in a Large-scale Randomized Controlled Trial	19
The Potential Role of Glutamate Receptors and their Antagonists or Modulators in Migraine Therapy	19
Virtual Screening-Based Drug Development for the Treatment of Nervous System Diseases	19
Current Insights into the Neurotoxicity of Melamine: A Comprehensive Review	19
The Role of Caspase Family in Acute Brain Injury: The Potential Therapeutic Targets in the Future	19
Machine Learning and Pharmacogenomics at the Time of Precision Psychiatry	19
Essential Oils in Experimental Models of Neuropsychiatric Disorders: A Systematic Review	19
Modulating Gut Microbiota: An Emerging Approach in the Prevention and Treatment of Multiple Sclerosis	18
Structural and Functional MRI Brain Changes in Patients with Schizophrenia Following Electroconvulsive Therapy: A Systematic Review	18
Tetrahydrobioterin (BH4) Pathway: From Metabolism to Neuropsychiatry	18
The Potential Influence of Associated Antidepressants on the Pharmacokinetic Profile of Esketamine in Patients Affected by Treatment-resistant Depression	18
Cariprazine Augmentation in Treatment-Resistant Bipolar Depression: Data from a Retrospective Observational Study	18
Receptors for Advanced Glycation End Products (RAGE): Promising Targets Aiming at the Treatment of Neurodegenerative Conditions	18
Neuroprotective Potential of Caffeic Acid Phenethyl Ester (CAPE) in CNS Disorders: Mechanistic and Therapeutic Insights	18
A New Augmentation Strategy against Depression Combining SSRIs and the N-terminal Fragment of Galanin (1-15)	18
Isolated Mitochondrial Preparations andIn organelloAssays: A Powerful and RelevantEx vivoTool for Assessment of Brain (Patho)physiology	17
Unveiling the Potential of Polyphenols as Anti-Amyloid Molecules in Alzheimer’s Disease	17
Meet the Editorial Board Member	17
Development of Non-opioid Analgesics Targeting Two-pore Domain Potassium Channels	17
Biomaterials for Neurotherapeutics: From Lab Discovery to Clinical Application	17
The Dorsolateral Prefrontal Cortex: A High-level Hub for Allostatic Cardiovascular Control	17
Targeting the Main Sources of Reactive Oxygen Species Production: Possible Therapeutic Implications in Chronic Pain	17
The Comprehensive Neural Mechanism of Oxytocin in Analgesia	17
Ufmylation: a potential modification for neurological diseases	17
Interleukin-17A in Alzheimer’s Disease: Recent Advances and Controversies	16
Pharmacological and Non-pharmacological Treatments of Sleep Disorders in Parkinson's Disease	16
Advances on Epigenetic Drugs for Pediatric Brain Tumors	16
The Diverse Network of Brain Histamine in Feeding: Dissect its Functions in a Circuit-Specific Way	16
Fabry Disease: Current and Novel Therapeutic Strategies. A Narrative Review	16
Challenges of Delirium Management in Patients with Traumatic Brain Injury: From Pathophysiology to Clinical Practice	16
Modulation of in vitro Network Activity by Optogenetic Stimulation of Parvalbumin-positive Interneurons During Estrous Cycle	16
Restoring Brain Pathways Involved in Diabetes-Associated Neurocognitive Disorders: The Potential of Dipeptidyl Peptidase 4 Inhibitors as a Therapeutic Strategy	16
An Update on Nondopaminergic Treatments for Motor and Non-motor Symptoms of Parkinson’s Disease	16
Secondary White Matter Injury Mediated by Neuroinflammation after Intracerebral Hemorrhage and Promising Therapeutic Strategies of Targeting the NLRP3 Inflammasome	16
Conventional and Emerging Drug Targeting Sites in Alzheimer’s Disease and the Role of Translational Informatics in its Diagnosis and Management	16
Cholesterol in Brain Development and Perinatal Brain Injury: More than a Building Block	15
Acknowledgements to Reviewers	15
Does the Brain Matter? Cortical Alterations in Pediatric Bipolar Disorder: A Critical Review of Structural and Functional Magnetic Resonance Studies	15
7,8-Dihydroxyflavone and Neuropsychiatric Disorders: A Translational Perspective from the Mechanism to Drug Development	15
Determining the Interaction in a Drug Combination using the Dose-based or Effect-based Method	15
Abusive use of Zolpidem as a Result of COVID-19 and Perspectives of Continuity of the Problem in the Post-Pandemic Period	15
The Role of Total White Blood Cell Count in Antipsychotic Treatment for Patients with Schizophrenia	15
Association of Oxidative Stress with Neurological Disorders	15
Natural Products-based Drugs: Potential Drug Targets Against Neurological Degeneration	15
A Bibliometric and Visual Analysis of Single Nucleotide Polymorphism Studies in Depression	14
Non-canonical Molecular Targets for Novel Analgesics: Intracellular Calcium and HCN Channels	14
Sleep Disturbance, Irritability, and Response to Lurasidone Treatment in Children and Adolescents with Bipolar Depression	14
How to Modulate Peripheral and Central Nervous System to Treat Acute Postoperative Pain and Prevent Pain Persistence	14
Galectin-3 in Microglia-Mediated Neuroinflammation: Implications for Central Nervous System Diseases	14
Pathways from the Superior Colliculus to the Basal Ganglia	14
Beneficial and Detrimental Effects of Uric Acid on Alzheimer’s Disease	14
Contributions of Zebrafish Studies to the Behavioural Consequences of Early Alcohol Exposure: A Systematic Review	14
Exploring the Effectiveness and Potential Pharmacological Mechanism of Minocycline for Spinal Cord Injury through Meta-Analysis and Network Pharmacology	14
Risks Associated with Vortioxetine in the Established Therapeutic Indication	14
Neurodegenerative Pathways in Alzheimer’s Disease: A Review	14
Striatal Acetylcholine and Dopamine Interactions Produce Situationappropriate Action Selection	14
Central Sensitization and Pain: Pathophysiologic and Clinical Insights	14
The Endocannabinoid System as Modulator of Exercise Benefits in Mental Health	14
Beyond its Psychiatric Use: The Benefits of Low-dose Lithium Supplementation	14
Potential of Medicinal Plants as Neuroprotective and Therapeutic Properties Against Amyloid-β-Related Toxicity, and Glutamate-Induced Excitotoxicity in Human Neural Cells	13
Meet Our Editorial Board Member	13
Epigenetic Mechanisms in the Pathophysiology and Progression of Epilepsy: A Comprehensive Review of Experimental and Clinical Studies	13
Meet the Country Editor	13
Patients Stratification Strategies to Optimize the Effectiveness of Scavenging Biogenic Aldehydes: Towards a Neuroprotective Approach for Parkinson's Disease	13

Emerging Neurobiological Concepts and Therapies for Neurological Rare Diseases	13
Drugs Used in the Treatment of Multiple Sclerosis During COVID-19 Pandemic: A Critical Viewpoint	13
Epigenetics of Fear, Anxiety and Stress – Focus on Histone Modifications	13
Preface	13
The Natural Protoalkaloid Methyl-2-Amino-3-Methoxybenzoate (MAM) Alleviates Positive as well as Cognitive Symptoms in Rat and Mouse Schizophrenia Models	13
Crosstalk Between Covid-19 and Associated Neurological Disorders: A Review	13
Inflammation Drives Alzheimer's Disease: Emphasis on 5-lipoxygenase Pathways	12
Symptoms of Protracted Alcohol Withdrawal in Patients with Alcohol Use Disorder: A Comprehensive Systematic Review	12
Extracellular Vesicles, Stem Cells and the Role of miRNAs in Neurodegeneration	12
Immune System and Methamphetamine: Molecular Basis of a Relationship	12
Antidepressant Prescription for Major Depressive Disorder: Results from a Population-Based Study in Italy	12
Contribution of Drugs to Drowning in Scotland from 1996 to 2020	12
Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin Norepinephrine Reuptake Inhibitors (SNRIs) During Pregnancy and the Risk for Autism spectrum disorder (ASD) and Attention deficit hyperact	12
Acid-Sensing Ion Channels: Focus on Physiological and Some Pathological Roles in the Brain	12
Epilepsy and Related Neuropsychiatric Comorbidities: Basic and Clinical Research	12
Neutrophil Heterogeneity and its Roles in the Inflammatory Network after Ischemic Stroke	12
Potential Benefits of Quercetin through P2X7 Modulation against Neuroinflammation in Alzheimer's Disease	12
Real-World Effectiveness of Cladribine for Patients with Multiple Sclerosis: A Sicilian Multicentric Experience (Rewind Study)	12
Meet the Section Editor	12
Update on Cannabidiol Clinical Toxicity and Adverse Effects: A Systematic Review	12
The Management and Alternative Therapies for Comorbid Sleep Disorders in Epilepsy	12
Baseline Plasma BDNF Levelsare Associated with Antianhedonic Effects of Repeated-Dose Intravenous Ketamine in Major Depressive Disorder	12
Meet Our Editorial Board Member	12
Differing Prevalence and Correlates of Metabolic Syndromes Between Chlorpromazine and Clozapine: A 10-year Retrospective Study of a Male Chinese Cohort	12
Bipolar Disorder and Manic-Like Symptoms in Alzheimer’s, Vascular and Frontotemporal Dementia: A Systematic Review	12
Glucocorticosteroids Effects on Brain Development in the Preterm Infant: A Role for Microglia?	12
Neurobehavioral Profiles of Six Genetically-based Rat Models of Schizophrenia- related Symptoms	12
Epilepsy and Cognitive Impairment in Childhood and Adolescence: A Mini-Review	12
Two Distinct Neuronal Populations in the Rat Parafascicular Nucleus Oppositely Encode the Engagement in Stimulus-driven Reward-seeking	11
Novel Synthetic and Natural Therapies for Traumatic Brain Injury	11
Effects of Alcohol on EEG Activity: A Systematic Review Focused on Sex-Related Differences in Youth	11
The Use of Zebrafish as a Non-traditional Model Organism in Translational Pain Research: The Knowns and the Unknowns	11
Meet the Co-Editor	11
Clinical Trials of Non-Coding RNAs as Diagnostic and Therapeutic Biomarkers for Central Nervous System Injuries	11
The Orexin System: A Potential Player in the Pathophysiology of Absence Epilepsy	11
Rethinking ‘Innovation’ in Psychiatry with Older and Newer Treatments: From Bench to Benchside	11
Microtubule-modulating Agents in the Fight Against Neurodegeneration: Will it ever Work?	11
Protective Role of Electroacupuncture Against Cognitive Impairment in Neurological Diseases	11
Progress in Neuropharmacology of Anesthetics and Analgesics for the Improvement of Medical Treatment	11
The Role of Neuroglial Metabotropic Glutamate Receptors in Alzheimer’s Disease	11
Association Between the COMT Val158Met Polymorphism and Antipsychotic Efficacy in Schizophrenia: An Updated Meta-Analysis	11
Olanzapine-Induced Weight Gain and Glycolipid Metabolism Aberrations in First-Episode and Antipsychotic-Naïve Schizophrenia Patients: A Longitudinal Study	11
The Role of High Mobility Group Box 1 (HMGB1) in Neurodegeneration: A Systematic Review	11
Anticholinesterases Traits Inbuilt in Buxaceae Plant Extracts against Alzheimer’s Disease	11
The Role of Autophagy in the Pathogenesis of Ischemic Stroke	11
Methods for Evaluating Sensory, Affective and Cognitive Disorders in Neuropathic Rodents	11
Promising Perspective to Facioscapulohumeral Muscular Dystrophy Treatment: Nutraceuticals and Phytochemicals	11