Current Cancer Drug Targets

Article	Citations
The Expression of Glutaminases and their Association with Clinicopathological Parameters in the Head and Neck Cancers	85
Combined RNAi of CTTN and FGF2 Modulates Cell Migration, Invasion and G1/S Transition of Hepatocellular Carcinoma through Ras/ERK Signaling Pathway	43
Spinal KCC2 Mediates the Modulation Effect of HDAC2 on Bone Cancer Pain in Rats	40
Micro-fragmented Fat Inhibits the Progression of Human Mesothelioma Xenografts in Mice	34
A Pilot Study of Anlotinib as a Combination Treatment in Advanced Nasopharyngeal Carcinoma	30
Unveiling Novel Therapeutic Drug Targets and Prognostic Markers of Triple Negative Breast Cancer	26
Silencing HEATR1 Rescues Cisplatin Resistance of Non-small Cell Lung Cancer by Inducing Ferroptosis via the p53/SAT1/ALOX15 Axis	25
Development of Chromatin Regulator-related Molecular Subtypes and a Signature to Predict Prognosis and Immunotherapeutic Response in Head and Neck Squamous Cell Carcinoma	24
Expression, Prognostic Value, and Immune Infiltration of MTHFD Family in Bladder Cancer	24
Knockdown of PRKD2 Enhances Chemotherapy Sensitivity in Cervical Cancer via the TP53/CDKN1A Pathway	23
Immune Checkpoint Inhibitors for Advanced Biliary Tract Cancer	22
The Therapeutic Potential of Urolithin A for Cancer Treatment and Prevention	22
Bioinformatics and Experimental Study Revealed LINC00982/ miR-183-5p/ABCA8 Axis Suppresses LUAD Progression	16
TBOPP, a DOCK1 Inhibitor, Potentiates Cisplatin Efficacy in Breast Cancer by Regulating Twist-mediated EMT	15
LMNB1/CDKN1A Signaling Regulates the Cell Cycle and Promotes Hepatocellular Carcinoma Progression	14
Progress in Metabolic Studies of Gastric Cancer and Therapeutic Implications	14
Etiology-based Molecular Characterization of Hepatocellular Carcinoma Reveals SQLE’s Contribution to Immunosuppressive Microenvironment	14
Efficacy and Safety of Immunotherapy Combined with Anlotinib as First-Line Treatment in Older NSCLC Patients with PD-L1 Expression<50%	13
Identification of ATM Mutation as a Potential Prognostic Biomarker for Immune Checkpoint Inhibitors Therapy	13
A Review on Patient-derived 3D Micro Cancer Approach for Drug Screen in Personalized Cancer Medicine	13
Use of Tumor-Infiltrating Lymphocyte (TIL) Cell Therapy For Spindle Cell Carcinoma of the Breast: A Case Report	12
Review Deciphering the Potential of Nanotherapeutics in Lung Cancer Management	12
Role of Natural Nuclear Factor Erythroid-2-related Factor 2 (Nrf2) Activators in Oral and Head and Neck Cancer Treatment	12
PLCG2, A Regulator of Lung Adenocarcinoma Proliferation and Migration Associated with Immune Infiltration	12
Targeting the HIF-1α/Cav-1 Pathway with a Chicory Extract/Daidzein Combination Plays a Potential Role in Retarding Hepatocellular Carcinoma	12

LINC00461 Knockdown Enhances the Effect of Ixazomib in Multiple Myeloma Cells	12
Inorganic Phosphate (Pi) in the Breast Cancer Microenvironment: Production, Transport and Signal Transduction as Potential Targets for Anticancer Strategies	12
Epigallocatechin-3-gallate Induced HepG2 Cells Apoptosis through ROSmediated AKT /JNK and p53 Signaling Pathway	11
High Expression of PKMYT1 Predicts Poor Prognosis and Aggravates the Progression of Osteosarcoma via the NF-κB Pathway in MG63 Cells	11
Low Expression of SCN4B Predicts Poor Prognosis in Non-small Cell Lung Cancer	11
Downregulation of CCKBR Expression Inhibits the Proliferation of Gastric Cancer Cells, Revealing a Potential Target for Immunotoxin Therapy	11
A Molecular Link Between Diabetes and Breast Cancer: Therapeutic Potential of Repurposing Incretin-based Therapies for Breast Cancer	11
EGF/EGFR Promotes Salivary Adenoid Cystic Carcinoma Cell Malignant Neural Invasion via Activation of PI3K/AKT and MEK/ERK Signaling	11
Protein Tyrosine Phosphatase 1B (PTP1B): Insights into its New Implications in Tumorigenesis	10
Nanodiamond Mediated Molecular Targeting in Pancreatic Ductal Adenocarcinoma: Disrupting the Tumor-stromal Cross-talk, Next Hope on the Horizon?	10
Utilization of DNA Replication factor MCM2 by Cancer	9
Comprehensive Pan-cancer Analysis of CMPK2 as Biomarker and Prognostic Indicator for Immunotherapy	9
Withaferin A Inhibits Liver Cancer Tumorigenesis by Suppressing Aerobic Glycolysis through the p53/IDH1/HIF-1α Signaling Axis	9
Preventive and Therapeutic effects of Metformin in Cancer: A Meta-Analysis of RCT and Cohort Studies	9
Real-world Study on the Effect of PARPi as Maintenance Therapy on Platinum Sensitivity after First- and Second-line Chemotherapy in Patients with Recurrent High-grade Serous Epithelial Ovarian Cancer	9
Solid CaCO3 Formation in Glioblastoma Multiforme and its Treatment with Ultra-Nanoparticulated NPt-Bionanocatalysts	9
Identification of AHSA1 as a Potential Therapeutic Target for Breast Cancer: Bioinformatics Analysis and in vitro Studies	9
WITHDRAWN: Hidrosmin Attenuates Inflammatory Response Induced by IL1β by Suppressing the Activation of NF-κB Involving Nrf2/HO1 Pathway in Human Osteoarthritis Chondrocytes	8
Angiotensin-converting Enzyme Inhibitors and Angiotensin Receptor Blockers as Potential Therapeutic Options for Pancreatic Cancer	8
Screening miRNAs to Hinder the Tumorigenesis of Renal Clear Cell Carcinoma Associated with KDR Expression	8
An Updated Review on Molecular Biomarkers in Diagnosis and Therapy of Colorectal Cancer	8
Anti-breast Cancer Potential of Prosopis cineraria L. Phytocompounds: A Network Pharmacology and in vitro Analysisbased Approach	8
Transcription Factor MAZ Potentiates the Upregulated NEIL3-mediated Aerobic Glycolysis, thereby Promoting Angiogenesis in Hepatocellular Carcinoma	8
CEA-regulated Oncolytic Virus Anticancer Therapy: A Promising Strategy for Rare Solid Tumors	8
Twenty-four-month Progression-free Survival in HER2-amplified Advanced Gastric Cancer with Brain Metastases after Trastuzumab Deruxtecan Treatment: A Case Report and Literature Review	8
Elucidating the Potential of E-cadherin Re-expression along with Trichostatin A and Zebularine in Enhancing Tumour Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)-Induced Apoptosis in Human	8
Gender Matters. Sex-related Differences in Immunotherapy Outcome in Patients with Non-small Cell Lung Cancer	7
A Saffron-based Polyherbal Formulation DuK Prevents Hepatocellular Carcinoma in Male Wistar Rats	7
FA-HA-Amygdalin@Fe2O3 and/or γ-Rays Affecting SIRT1 Regulation of YAP/TAZ-p53 Signaling and Modulates Tumorigenicity of MDA-MB231 or MCF-7 Cancer Cells	7
Efficacy and Safety of Phosphatidylinositol 3-kinase Inhibitors for Patients with Breast Cancer: A Systematic Review and Meta-analysis of Randomized Controlled Trials	7
Progressive Dynamics of Cancer Stem Cells in Oral Squamous Cell Carcinoma	7
Silencing TRIM29 Sensitizes Non-small Cell Lung Cancer Cells to Anlotinib by Promoting Apoptosis via Binding RAD50	7
Spleen Glucose Metabolism on [18F]-FDG PET/CT for Cancer Drug Discovery and Development cannot be Overlooked	7
Recent Advancements in Drug Targeting for Ferroptosis as an Antitumor Therapy: Development of Novel therapeutics	7
Promotion of Cervical Cancer Cell Proliferation by miR-130b Expression Level Changes and Inhibition of its Apoptosis by Targeting CDKN1A Gene	7
Curcumin Inhibits Vasculogenic Mimicry via Regulating ETS-1 in Renal Cell Carcinoma	7
Advances and Future Prospects of Lipid-Based Nanocarriers in Targeted Cancer Therapy: A Comprehensive Review	7
Cancer Vaccine in Cold Tumors: Clinical Landscape, Challenges, and Opportunities	7
HIF-1α/Malat1/miR-141 Axis Activates Autophagy to Increase Proliferation, Migration, and Invasion in Triple-negative Breast Cancer	7
Neuronatin Promotes the Progression of Non-small Cell Lung Cancer by Activating the NF-κB Signaling	7
Targeting Glutamine Metabolic Reprogramming in Pancreatic Cancer: Current Insights and Future Directions	7
Stabilizing Scaffold for Short Peptides Based on Knottins	7
Precision Medicine in Colorectal Cancer: Targeted Therapies and Biomarker Insights	7
CDK8 as a therapeutic target for overall survival prediction in cervical squamous cell carcinoma (CESC)	7
RON Receptor Tyrosine Kinase in Tumorigenic Stemness as a Therapeutic Target of Antibody-drug Conjugates for Eradication of Triple-negative Breast Cancer Stem Cells	7
Combinatorial Application of Papain and CD66B for Isolating Glioma- Associated Neutrophils	6
Elucidation of the Role of the Epigenetic Regulatory Mechanisms of PI3K/Akt/mTOR Signaling Pathway in Human Malignancies	6
Exosome-mediated Induction of Apoptosis in Cisplatin-treated Gastric Cancer Cells as a Strategy to Mitigate Side Effects	6
Current Challenges in Targeting Tumor Desmoplasia to Improve the Efficacy of Immunotherapy	6
Single Nucleotide Polymorphisms as the Efficient Prognostic Markers in Breast Cancer	6

Autophagy in Cancer Cell Transformation: A Potential Novel Therapeutic Strategy	6
COL10A1 as a Prognostic Biomarker in Association with Immune Infiltration in Prostate Cancer	6
Is the Use of SGLT-2 Associated with an Increased Risk of Cancer?	6
Silencing of FANCI Promotes DNA Damage and Sensitizes Ovarian Cancer Cells to Carboplatin	6
The Imidazacridine Derivative LPSF/AC-05 Induces Apoptosis, Cell Cycle Arrest, and Topoisomerase II Inhibition in Breast Cancer, Leukemia, and Lymphoma	6
Exploring the Impact of Chitosan-Based Nanoparticles in Cancer Targeted Drug Delivery: A Bibliometric Review	6
TROP2 Down-regulated DSG2 to Promote Gastric Cancer Cell Invasion and Migration by EGFR/AKT and DSG2/PG/β-Catenin Pathways	6
A Novel Platinum-Resistance-related Gene Signature in Ovarian Cancer: Identification and Patient-derived Organoids Verification	6
Exploring the Role of Long Non-Coding RNAs in Mediating Cisplatin Resistance in Colorectal Cancer	6
Chimeric Antigen Receptor (CAR) T-cell Therapy: A New Genetically Engineered Method of Immunotherapy for Cancer	6
Assessing Long Non-coding RNAs in Tobacco-associated Oral Cancer	6
Pathological Implications of Mucin Signaling in Metastasis	6
Research Advances of Clinical Application of Oncolytic Viruses in Treatment of Gynecologic Cancers	5
The Clinical Role of Hypoxia Inducible Factor (HIF) Inhibition in Renal Cancer: A Focus on Belzutifan	5
Advances in Radiation Therapy Enhancement and Radio-Protection By Nano-Curcumins: A Systematic Review	5
mirna-383-5p Functions as an Anti-oncogene in Glioma through the Akt/mTOR Signaling Pathway by Targeting VEGFA	5
Comparison of Surgical and Colonoscopy Tissue to Establish Colorectal Patient-derived Organoids	5
RAD50 Deficient in a Breast Cancer Model Predicts Sensitivity to PARP Inhibitors	5
Cuproptosis Related Gene DLD Associated with Poor Prognosis and Malignant Biological Characteristics in Lung Adenocarcinoma	5
Combination Therapy with Androgen Receptor Pathway Inhibitors for Prostate Cancer	5
Nanotechnological Advancements for the Theranostic Intervention in Anaplastic Thyroid Cancer: Current Perspectives and Future Direction	5
ADH1B Gene Promotes Gastric Cancer Tumorigenesis and its Cisplatin Resistance through the EMT Pathway	5
Coriandrum sativum and Aloysia triphylla can Protect the Development of Cancer: An in Vivo Study using Mouse Painting Assay	5
L-lysine Increases the Anticancer Effect of Doxorubicin in Breast Cancer by Inducing ROS-dependent Autophagy	5
Unveiling the Therapeutic Potential of Compounds Carrying Mono- and Bis-Thiazole Nuclei with Distinct Heterocyclic Analogues for Addressing Cancer Challenges	5
ZIP14 Affects the Proliferation, Apoptosis, and Migration of Cervical Cancer Cells by Regulating the P38 MAPK Pathway	5
Molecular Targets and Nano-Technological Approaches in the Treatment of Hepatic Carcinoma	5
UCA1 Inhibits NKG2D-mediated Cytotoxicity of NK Cells to Breast Cancer	5
Repurposing of Antidiarrheal Loperamide for Treating Melanoma by Inducing Cell Apoptosis and Cell Metastasis Suppression In vitro and In vivo	5
WEE Family Kinase Inhibitors Combined with Sorafenib Can Selectively Inhibit HCC Cell Proliferation	5
A Novel Oncogenic Role of Disulfidptosis-related Gene SLC7A11 in Anti-tumor Immunotherapy Response to Human Cancers	5
Tumor-Activated Neutrophils Promote Lung Cancer Progression through the IL-8/PD-L1 Pathway	5
Targeting the Tumor Epigenetic Regulator SETDB1 for Tumor Therapy	4
The Effects of Mesenchymal Stem Cells Loaded with Oncolytic Coxsackievirus A21 on Mouse Models of Colorectal Cancer	4
Present and Future Prospects of the Anti-cancer Activities of Saikosaponins	4
Combined Immunotherapy and Targeted Therapies for Cancer Treatment: Recent Advances and Future Perspectives	4
The Association between NADPH Oxidase 2 (NOX2) and Drug Resistance in Cancer	4
Preface	4
Mitochondrial Calcium Uniporter (MCU) that Modulates Mitochondrial Calcium Uptake and Facilitates Endometrial Cancer Progression through Interaction with VDAC1	4
VX-765 has a Protective Effect on Mice with Ovarian Injury Caused by Chemotherapy	4
Forkhead Box Protein M1 (FOXM1): Prospective Prognostic Biomarker and Therapeutic Targets in Oral Cancer	4
Angiogenesis and Pancreatic Cancer: Novel Approaches to Overcome Treatment Resistance	4
Sildenafil Inhibits the Growth and Epithelial-to-mesenchymal Transition of Cervical Cancer via the TGF-β1/Smad2/3 Pathway	4
AHNAK2 Promotes the Progression of Differentiated Thyroid Cancer through PI3K/AKT Signaling Pathway	4
Dihydrotanshinone I Inhibits Pancreatic Cancer Progression via Hedgehog/ Gli Signal Pathway	4
Up-regulation of Core 1 Beta 1, 3-Galactosyltransferase Suppresses Osteosarcoma Growth with Induction of IFN-γ Secretion and Proliferation of CD8+ T Cells	4
Polyphyllin VII is a Potential Drug Targeting CD44 Positive Colon Cancer Cells	4
The Role of Local Angiotensin II/Angiotensin Type 1-receptor Mechanisms in Adipose Tissue Dysfunction to Promote Pancreatic Cancer	4
Preface	4
The Influence of KIR Gene Polymorphisms and KIR-ligand Binding on Outcomes in Hematologic Malignancies following Haploidentical Stem Cell Transplantation: A Comprehensive Review	4
Research Progress of Neural Invasion in Pancreatic Cancer	4
Dietary Flavonoids with Catechol Moiety Inhibit Anticancer Action of Bortezomib: What about the other Boronic Acid-based Drugs?	4
Resistance of Lenvatinib in Hepatocellular Carcinoma	4
Efficacy and Safety of Nimotuzumab in Combination with Radiotherapy or Chemoradiotherapy for Local Advanced Head and Neck Cancer: A Systematic Review and Meta-analysis	4
Durable Disease-free Survival in a Patient with Metastatic Triple-negative Breast Cancer Treated with Olaparib Monotherapy	4
Perspectives on Ergodic Cancer Therapy Derived from Cloning Genome Chaos via In Vivo Rhabdomyosarcoma RA-2 Models: a Narrative Review	4
Disulfiram-Copper Potentiates Anticancer Efficacy of Standard Chemotherapy Drugs in Bladder Cancer Animal Model through ROS-Autophagy-Ferroptosis Signalling Cascade	4
Antibody-drug Conjugate Targets, Drugs, and Linkers	4
IR-780 Dye-based Targeting of Cancer-associated Fibroblasts Improves Cancer Immunotherapy by Increasing Intra-tumoral T Lymphocytes Infiltration	4
The Prognostic Value and Clinical Significance of lncRNA SNHG5 Expression in Patients with Multiple Malignancies: A Bioinformatic and Meta-analysis	3
RC48 Induces Senescence in HER2-Expressing Colon Cancer Cells by Activating the CDKN1A-RB-E2F1 Pathway	3
Advancements in Phytosomal Therapies for Liver Cancer: A Comprehensive Review	3
The Role of Oxidative Stress in the Development and Therapeutic Intervention of Hepatocellular Carcinoma	3
Deubiquitylase USP31 Induces Autophagy and Promotes the Progression in Lung Squamous Cell Carcinoma Cells by Stabilizing E2F1 Expression	3
The Therapeutic Potential of MAPK/ERK Inhibitors in the Treatment of Colorectal Cancer	3
WITHDRAWN: Network Pharmacology and In vitro Experiments Reveal that Noscapine Induces Ros-mediated Apoptosis and Cell Cycle Arrest via PI3K/Akt/FoxO3a Signaling Pathway in Human Bladder Cancer Cells	3
Current Perspectives in Ultra-sensitive Detection of Cancer-specific Biomarkers and Therapeutic Targets	3
Embracing the Circular Journey of RNA in Colorectal Cancer	3
Raddeanoside R13 Inhibits Proliferation, Invasion, and Metastasis of Gastric Cancer Cells Based on Network Pharmacology and Experimental Validation	3
CircRNAs Regulate Senescence-Associated miRNAs in Gastric Cancer	3
GPX4 Inhibition Enhances the Antitumor Effect of PARP Inhibitor on Homologous Recombination Proficient Ovarian Cancer Cells	3
Modifications of Ribonucleases in Order to Enhance Cytotoxicity in Anticancer Therapy	3
Smart Nanobiomaterials for Gene Delivery in Localized Cancer Therapy: An Overview from Emerging Materials and Devices to Clinical Applications	3
Insights into the Emerging Therapeutic Targets of Triple-negative Breast Cancer	3
Experimental Determination of Cancer Drug Targets with Independent Mechanisms of Resistance	3
Corrigendum to: Low Expression MCEMP1 Promotes Lung Adenocarcinoma Progression and its Clinical Value	3
Exosomes Mediate the Production of Oxaliplatin Resistance and Affect Biological Behaviors of Colon Cancer Cell Lines	3
H3K27ac-activated LncRNA NUTM2A-AS1 Facilitated the Progression of Colorectal Cancer Cells via MicroRNA-126-5p/FAM3C Axis	3
LINC00887 Acts as an Enhancer RNA to Promote Medullary Thyroid Carcinoma Progression by Binding with FOXQ1	3
Netupitant-palonosetron (NEPA) for Preventing Chemotherapy-induced Nausea and Vomiting: From Clinical Trials to Daily Practice	3

Gastroenteropancreatic Neuroendocrine Neoplasms (GEP NENs): The Role of Checkpoint Inhibitors	3
Traditional Chinese Medicine Targeting Sarcoma Virus Oncogene-related Diseases	3
Comprehensive Pan-cancer Analysis and Experimental Verification of EGLN Family: Potential Biomarkers in Cervical Cancer	3
GAPVD1 Promotes the Proliferation of Triple-negative Breast Cancer Cells by Regulating the ERK/MAPK Signaling Pathway	3
Recent Progress in the Application of Exosome Analysis in Ovarian Cancer Management	3
Metastatic Breast Cancer, Organotropism and Therapeutics: A Review	3
Dextran Sulfate Inhibits Cell Proliferation and Induces Apoptosis by Regulating EZH2 in Gastric Carcinoma	3
Mechanism of Bispecific Antibodies and Clinical Research Advances in Lung Cancer	3
Probiotics as a Therapeutic Approach in Colorectal Cancer	3
DTL is a Novel Downstream Gene of E2F1 that Promotes the Progression of Hepatocellular Carcinoma	3
Clinical Efficacy and Safety of Anlotinib Combined with Immune Checkpoint Inhibitors in the Treatment of Advanced Squamous Cell Lung Cancer: A Retrospective Single-Center Study in China	3
Effects of HSV-G47Δ Oncolytic Virus on Telomerase and Telomere Length Alterations in Glioblastoma Multiforme Cancer Stem Cells Under Hypoxia and Normoxia Conditions	3
CT109-SN-38, a Novel Antibody-drug Conjugate with Dual Specificity for CEACAM5 and 6, Elicits Potent Killing of Pancreatic Cancer Cells	3
Study on Cellular Localization of Bin Toxin and its Apoptosis-inducing Effect on Human Nasopharyngeal Carcinoma Cells	3
Εmerging Biomarkers in the Diagnosis and Treatment of Testicular Tumors	3
PIWIL1 Promotes Malignant Progression of Papillary Thyroid Carcinoma by Inducing EVA1A Expression	2
Envafolimab Inhibits the Growth of Gastric Cancer Cells with Low PD-L1 Expression through the DDX20/NF-κB/TNF-α Signaling Pathway	2
Advances in Ovarian Cancer Treatment Beyond PARP Inhibitors	2
Value of Label-Free Ubiquitin-Proteomic Analysis on Defining the Protective Mechanism of Valsartan against Doxorubicin-Induced Heart Failure	2
Construction of an Oxidative Stress Risk Model to Analyze the Correlation Between Liver Cancer and Tumor Immunity	2
Cucurbitacin D Inhibits the Proliferation of HepG2 Cells and Induces Apoptosis by Modulating JAK/STAT3, PI3K/Akt/mTOR and MAPK Signaling Pathways	2
Impact of GSTT1 and GSTM1 Polymorphisms in the Susceptibility to Philadelphia Negative Chronic Myeloid Leukaemia	2
Preparation of Modified Chitosan-based Nanoparticles for Efficient Delivery of Doxorubicin and/or Cisplatin to Breast Cancer Cells	2
WITHDRAWN: Comprehensive Analysis of the Role of CXCL Family Members in Clear Cell Renal Cell Carcinoma	2
Dysregulated Epigenetics of Chordoma: Prognostic Markers and Therapeutic Targets	2
EWS-RNA Binding Protein 1: Structural Insights into Ewing Sarcoma by Conformational Dynamics Investigations	2
Novel Synergistic Combination of Pamidronate and Temozolomide for Breast Cancer Therapeutics	2
The Tumor Immune Microenvironment plays a Key Role in Driving the Progression of Cholangiocarcinoma	2
MALAT1 Promotes Tumorigenesis and Increases Cellular Sensitivity to Herceptin in HER2-positive Breast Cancer	2
Advancement and Strategies for the Development of Peptide-drug Conjugates: Pharmacokinetic Modulation, Role and Clinical Evidence against Cancer Management	2
Targeting Ferroptosis Pathways: A Novel Strategy for Cancer Therapy	2
SULF1 Activates the VEGFR2/PI3K/AKT Pathway to Promote the Development of Cervical Cancer	2
Low Expression MCEMP1 Promotes Lung Adenocarcinoma Progression and its Clinical Value	2
CDK-associated Cullin 1 Promotes Cell Proliferation and Inhibits Cell Apoptosis in Human Glioblastoma	2
Novel Association of RAD54L Mutation with Müllerian Clear Cell Carcinoma of the Male Urethra: New Insights Regarding the Molecular Mechanisms of a Rare Tumour	2
The Potential of Natural Products in the Treatment of Triple-negative Breast Cancer	2
IL-33/ST2 Signaling and its Correlation with Macrophage Heterogeneity and Clinicopathologic Features in Human Intrahepatic Cholangiocarcinoma	2
An Overview of the Dichotomous Role of Microbiota in Cancer Progression and Management	2
Biology, Significance and Immune Signaling of Mucin 1 in Hepatocellular Carcinoma	2
Effect of HPV Oncoprotein on Carbohydrate and Lipid Metabolism in Tumor Cells	2
SPON2 Suppresses Autophagy by Regulating the PI3K/AKT/mTOR Signaling Pathway in Renal Cell Carcinoma	2
Treatment Advances in Lung Cancer with Leptomeningeal Metastasis	2
Overexpression of BRD4 in Gastric Cancer and its Clinical Significance as a Novel Therapeutic Target	2
A Pan-cancer Analysis to Determine the Prognostic Analysis and Immune Infiltration of HSPA5	2
The Role of Lactate in Cancer Immunotherapy: Mechanisms and Applications	2
Advances in Understanding How RhoB Regulates Akt Inhibition Efficacy in NSCLC	2
Geiparvarin Inhibits the Progression of Osteosarcoma by Down-regulating COX2 Expression	2
A Review of the Progress in the Diagnosis and Treatment of Pulmonary Sarcomatoid Carcinoma	2
Emerging Prospects for the Study of Colorectal Cancer Stem Cells using Patient-derived Organoids	2
Role of Non-Coding RNAs in Regulating PD-L1 Expression in Breast Cancer: Emerging Insights and Implications	2
EVI5 Drives Lung Adenocarcinoma Progression through Modulation of the ERK1/2-c-Myc Signaling Axis	2
Increase in Cisplatin Resistance by MeCP2 in Human Gastric Cancer through the Activation of the AKT Pathway by Facilitating PDK-1 Transcription	2
Promotion of Melanoma Progression through MCM4-Induced Immune Suppression and Polarization of Macrophages by Carcinogenic Exosomes	1
Knockdown of ARL5B Induces Mitochondrial-mediated Apoptosis and Inhibits Glycolysis in Breast Cancer Cells by Activating MDA5 Signaling	1
Growth-hormone-releasing Hormone as a Prognostic Biomarker and Therapeutic Target in Gastrointestinal Cancer	1
Targeting the Transforming Growth Factor-beta Signaling Pathway in the Treatment of Gynecologic Cancer	1
The Therapeutic Potential of Targeting Autophagy in the Treatment of Cancer	1
Vitamin D Affects the Warburg Effect and Stemness Maintenance of Non- Small-Cell Lung Cancer Cells by Regulating the PI3K/AKT/mTOR Signaling Pathway	1
Comprehensive Analysis of Diabetes Mellitus-related Gene Expression and Associated Prognoses in Human Lung Cancer	1
High Level of Adropin Promotes the Progression of Pancreatic Ductal Adenocarcinoma	1
Advanced Engineered Nanoplatforms to Overcome Biological Barriers for Targeting Brain Tumors	1
EZH2-regulated PARP-1 Expression is a Likely Mechanism for the Chemoresistance of Gliomas to Temozolomide	1
The Long Noncoding RNA PANDAR as a Prognostic and Diagnostic Biomarker in Panceratic Cancer	1
The Mutation and Low Expression of ARID1A are Predictive of a Poor Prognosis and High Immune Infiltration in Triple-negative Breast Cancer	1
Cancer Vaccines: Mechanisms, Clinical Applications, Challenges, and Future Directions in Precision Medicine	1
Arsenic Trioxide Restrains Lung Cancer Growth and Metastasis by Blocking the Calcineurin-NFAT Pathway by Upregulating DSCR1	1
Transforming Cancer Care: The Impact of AI-driven Strategies	1
Polycaprolactone-based Nanocarriers Containing 5-fluorouracil as a Therapeutic Guided Drug Delivery Approach for Enhancing Anticancer Activity	1
Liquid-Liquid Phase Separation in the Prognosis of Lung Adenocarcinoma: An Integrated Analysis	1
Application of Thermoresponsive Smart Polymers based in situ Gel as a Novel Carrier for Tumor Targeting	1
C-C Motif Chemokine Ligand 5 (CCL5): A Potential Biomarker and Immunotherapy Target for Osteosarcoma	1
Anti-cancer Effects of 5-Aminoimidazole-4-Carboxamide-1-β-D-Ribofuranoside (AICAR) on Triple-negative Breast Cancer (TNBC) Cells: Mitochondrial Modulation as an Underlying Mechanism	1
Modulation of ATP8B1 Gene Expression in Colorectal Cancer Cells Suggest its Role as a Tumor Suppressor	1
Cardiovascular Mortality Risk Among Patients with Liver Cancer: A SEER Database Study	1
Pharmacological Targeting of Ferroptosis in Cancer Treatment	1
Regulatory Effect of Non-Coding RNAs on Programmed Cell Death in Melanoma: Novel Therapeutic Crosstalk for Targeted Therapy	1
cGAS-STING Pathway as the Target of Immunotherapy for Lung Cancer	1
A Comprehensive Evaluation of the Effectiveness and Safety of Pembrolizumab for the Treatment of Metastatic Colorectal Cancer: A Systematic Review and Meta-Analysis	1
Pharmacological Inhibition of Exosome Machinery: An Emerging Prospect in Cancer Therapeutics	1
Evaluation of the Antitumoral Effect of PI3K/AKT/mTOR Pathway Inhibition and Antioxidant Combination on Burkitt Lymphoma Cell Line	1
Biomacromolecule-Functionalized Nanoparticle-Based Conjugates for Potentiation of Anticancer Therapy	1
Nanocarrier System for Increasing the Therapeutic Efficacy of Oxaliplatin	1
Role of NADPH Quinone Reductase 1 (NQO1) Polymorphism in Prevention, Diagnosis, and Treatment of Gastrointestinal Cancers	1
Gamma-tocotrienol Inhibits Proliferation and Growth of HSD17B4 Overexpressing HepG2 Liver Cancer Cells	1
Tectorigenin Inhibits Glycolysis-induced Cell Growth and Proliferation by Modulating LncRNA CCAT2/miR-145 Pathway in Colorectal Cancer	1
Dextran Sulfate Inhibits Angiogenesis and Invasion of Gastric Cancer by Interfering with M2-type Macrophages Polarization	1
Single-Cell Transcriptomics: Technical Advances, Applications and Challenges in Cancer Drug Discovery	1
Promising Response to Pyrotinib in Non-Small-Cell Lung Cancer with the Rare HER2 R456C Mutation: A Case Report	1
Dendrobine Suppresses Tumor Growth by Regulating the PD-1/PD-L1 Checkpoint Pathway in Lung Cancer	1
Novel Compound, ND-17, Regulates the JAK/STAT, PI3K/AKT, and MAPK Pathways and Restrains Human T-lymphoid Leukemia Development	1
Groundbreaking mRNA Lung Cancer Vaccine Trials: A New Dawn in Cancer Treatment	1
Nucleolin as a Crucial Player in Head and Neck Cancer: Diagnostic and Therapeutic Perspectives	1
Exploring the Antitumor Efficacy of PEGylated Liposomes Loaded with Licorice Extract for Cancer Therapy	1
Therapeutic Potential of Clostridium novyi-NT in Cancer: Current Knowledge and Future Perspectives	1
Immunotherapy for Gastroesophageal Tumors: Is there still Hope for Efficacy?	1