Current Cancer Drug Targets

Article	Citations
LMNB1/CDKN1A Signaling Regulates the Cell Cycle and Promotes Hepatocellular Carcinoma Progression	98
Immune Checkpoint Inhibitors for Advanced Biliary Tract Cancer	48
Development of Chromatin Regulator-related Molecular Subtypes and a Signature to Predict Prognosis and Immunotherapeutic Response in Head and Neck Squamous Cell Carcinoma	40
Expression, Prognostic Value, and Immune Infiltration of MTHFD Family in Bladder Cancer	40
Knockdown of PRKD2 Enhances Chemotherapy Sensitivity in Cervical Cancer via the TP53/CDKN1A Pathway	33
Artesunate overcomes lenvatinib resistance by inhibiting the STAT3/SLC25A27 pathway and promoting ferroptosis in hepatocellular carcinoma	32
Etiology-based Molecular Characterization of Hepatocellular Carcinoma Reveals SQLE's Contribution to Immunosuppressive Microenvironment	32
A Review on Patient-derived 3D Micro Cancer Approach for Drug Screen in Personalized Cancer Medicine	28
Bioinformatics and Experimental Study Revealed LINC00982/ miR-183-5p/ABCA8 Axis Suppresses LUAD Progression	22
DDX18 as a Prognostic Biomarker Associated with Pan-Cancer Immune Infiltration and Drug Sensitivity	21
Micro-fragmented Fat Inhibits the Progression of Human Mesothelioma Xenografts in Mice	19
Combined RNAi of CTTN and FGF2 Modulates Cell Migration, Invasion and G1/S Transition of Hepatocellular Carcinoma through Ras/ERK Signaling Pathway	19
A Pilot Study of Anlotinib as a Combination Treatment in Advanced Nasopharyngeal Carcinoma	19
Ectophosphatase Activity in Human Hepatocellular Carcinoma Huh7 Cells: Characterisation and Implications for the Tumour Microenvironment	18
The Therapeutic Potential of Urolithin A for Cancer Treatment and Prevention	18
Leveraging a Disulfidptosis-related LncRNA Prognostic Signature to Indicate Immune Features and Drug Sensitivity of Gastric Cancer Based on Machine Learning	18
Spinal KCC2 Mediates the Modulation Effect of HDAC2 on Bone Cancer Pain in Rats	17
Silencing HEATR1 Rescues Cisplatin Resistance of Non-small Cell Lung Cancer by Inducing Ferroptosis via the p53/SAT1/ALOX15 Axis	17
Precision Strategies for Normal Tissue Radiotoxicity: Biomarkers, AI, and Nanomedicine in Clinical Practice	17
NRF2-Driven CARM1 Promotes Malignant Progression and Ferroptosis Resistance in Breast Cancer	17
Efficacy and Safety of Immunotherapy Combined with Anlotinib as First-Line Treatment in Older NSCLC Patients with PD-L1 Expression<50%	16
FHOD3 Promotes the Progression of Lung Cancer by Regulating the Caspase-3-Mediated Signaling Pathway	16
Identification of ATM Mutation as a Potential Prognostic Biomarker for Immune Checkpoint Inhibitors Therapy	15
MiR-124-3p Suppresses Glioma Cells Progression by Targeting STAT3/NAMPT and Inhibiting AKT/ERK Signaling	15
TBOPP, a DOCK1 Inhibitor, Potentiates Cisplatin Efficacy in Breast Cancer by Regulating Twist-mediated EMT	15

WITHDRAWN: Use of Tumor-Infiltrating Lymphocyte (TIL) Cell Therapy for Spindle Cell Carcinoma of the Breast: A Case Report	14
Progress in Metabolic Studies of Gastric Cancer and Therapeutic Implications	14
LINC00461 Knockdown Enhances the Effect of Ixazomib in Multiple Myeloma Cells	14
Role of Natural Nuclear Factor Erythroid-2-related Factor 2 (Nrf2) Activators in Oral and Head and Neck Cancer Treatment	14
PLCG2, A Regulator of Lung Adenocarcinoma Proliferation and Migration Associated with Immune Infiltration	13
Review Deciphering the Potential of Nanotherapeutics in Lung Cancer Management	13
CircRNAs Crosstalk with Key Signaling Proteins in the Progression of Hepatocellular Carcinoma	13
EGF/EGFR Promotes Salivary Adenoid Cystic Carcinoma Cell Malignant Neural Invasion via Activation of PI3K/AKT and MEK/ERK Signaling	13
Low Expression of SCN4B Predicts Poor Prognosis in Non-small Cell Lung Cancer	13
Inorganic Phosphate (Pi) in the Breast Cancer Microenvironment: Production, Transport and Signal Transduction as Potential Targets for Anticancer Strategies	12
Epigallocatechin-3-gallate Induced HepG2 Cells Apoptosis through ROSmediated AKT /JNK and p53 Signaling Pathway	12
MMP7, Regulated by c-Jun, is Involved in Oral Squamous Cell Carcinoma and Associated with Cancer-Related Fibroblasts Infiltration	12
Nanodiamond Mediated Molecular Targeting in Pancreatic Ductal Adenocarcinoma: Disrupting the Tumor-stromal Cross-talk, Next Hope on the Horizon?	12
High Expression of PKMYT1 Predicts Poor Prognosis and Aggravates the Progression of Osteosarcoma via the NF-κB Pathway in MG63 Cells	12
Solid CaCO3 Formation in Glioblastoma Multiforme and its Treatment with Ultra-Nanoparticulated NPt-Bionanocatalysts	11
WITHDRAWN: Hidrosmin Attenuates Inflammatory Response Induced by IL1β by Suppressing the Activation of NF-κB Involving Nrf2/HO1Pathway in Human Osteoarthritis Chondrocytes	11
Comparative Analysis of Homologous Recombination Repair Status Across Gynecologic and Breast Cancers in Chinese Populations	11
Real-world Study on the Effect of PARPi as Maintenance Therapy on Platinum Sensitivity after First- and Second-line Chemotherapy in Patients with Recurrent High-grade Serous Epithelial Ovarian Cancer	11
Utilization of DNA Replication factor MCM2 by Cancer	11
An Updated Review on Molecular Biomarkers in Diagnosis and Therapy of Colorectal Cancer	11
Elucidating the Potential of E-cadherin Re-expression along with Trichostatin A and Zebularine in Enhancing Tumour Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)-Induced Apoptosis in Human	11
Withaferin A Inhibits Liver Cancer Tumorigenesis by Suppressing Aerobic Glycolysis through the p53/IDH1/HIF-1α Signaling Axis	11
Anti-breast Cancer Potential of Prosopis cineraria L. Phytocompounds: A Network Pharmacology and in vitro Analysisbased Approach	11
Aurora Kinases as Potential Therapeutic Targets for Tumors with pRB and/or MYCN Dysregulation	11
Preventive and Therapeutic effects of Metformin in Cancer: A Meta- Analysis of RCT and Cohort Studies	10
A Novel Oncogene and Therapeutic Target, Germ Cell-Specific Gene 2 (GSG2), Plays Complex Roles in Promoting Malignant Progression of Glioma	10
Inhibition of CD24 Expression Enhances the Anti-Melanoma Effect of Endostatin by Ameliorating Anti-Tumor Immune Responses in Melanoma-Bearing Mice	10
Twenty-four-month Progression-free Survival in HER2-amplified Advanced Gastric Cancer with Brain Metastases after Trastuzumab Deruxtecan Treatment: A Case Report and Literature Review	10
Angiotensin-converting Enzyme Inhibitors and Angiotensin Receptor Blockers as Potential Therapeutic Options for Pancreatic Cancer	10
Stabilizing Scaffold for Short Peptides Based on Knottins	10
Transcription Factor MAZ Potentiates the Upregulated NEIL3-mediated Aerobic Glycolysis, thereby Promoting Angiogenesis in Hepatocellular Carcinoma	10
Comprehensive Pan-cancer Analysis of CMPK2 as Biomarker and Prognostic Indicator for Immunotherapy	10
A Saffron-based Polyherbal Formulation DuK Prevents Hepatocellular Carcinoma in Male Wistar Rats	10
Neuronatin Promotes the Progression of Non-small Cell Lung Cancer by Activating the NF-κB Signaling	9
Recent Advancements in Drug Targeting for Ferroptosis as an Antitumor Therapy: Development of Novel therapeutics	9
Gender Matters. Sex-related Differences in Immunotherapy Outcome in Patients with Non-small Cell Lung Cancer	9
Patterns and Predictors of Carboplatin-Induced Myelotoxicity in Breast Cancer Patients: A Six-Year Retrospective Analysis	9
Precision Medicine in Colorectal Cancer: Targeted Therapies and Biomarker Insights	9
FA-HA-Amygdalin@Fe2O3 and/or γ-Rays Affecting SIRT1 Regulation of YAP/TAZ-p53 Signaling and Modulates Tumorigenicity of MDA-MB231 or MCF-7 Cancer Cells	9
Long Non-Coding RNA HCP5 Affects Ferroptosis in Lung Adenocarcinoma through miR-17-5p/HOXA7 Axis	9
Screening miRNAs to Hinder the Tumorigenesis of Renal Clear Cell Carcinoma Associated with KDR Expression	9
Targeting Glutamine Metabolic Reprogramming in Pancreatic Cancer: Current Insights and Future Directions	9
RON Receptor Tyrosine Kinase in Tumorigenic Stemness as a Therapeutic Target of Antibody-drug Conjugates for Eradication of Triple-negative Breast Cancer Stem Cells	9
Curcumin Inhibits Vasculogenic Mimicry via Regulating ETS-1 in Renal Cell Carcinoma	9
Progressive Dynamics of Cancer Stem Cells in Oral Squamous Cell Carcinoma	8
Resistance Mechanisms of Alectinib in ALK-Positive Non-Small Cell Lung Cancer and Therapeutic Strategies	8
TROP2 Down-regulated DSG2 to Promote Gastric Cancer Cell Invasion and Migration by EGFR/AKT and DSG2/PG/β-Catenin Pathways	8
Efficacy and Safety of Phosphatidylinositol 3-kinase Inhibitors for Patients with Breast Cancer: A Systematic Review and Meta-analysis of Randomized Controlled Trials	8
Autophagy in Cancer Cell Transformation: A Potential Novel Therapeutic Strategy	8
CDK8 as a therapeutic target for overall survival prediction in cervical squamous cell carcinoma (CESC)	8

HIF-1α/Malat1/miR-141 Axis Activates Autophagy to Increase Proliferation, Migration, and Invasion in Triple-negative Breast Cancer	8
In Silico Multi-omics Analyses of Kinesin Family Member 15 in Pan-Cancer and Validation in Tissue Microarray	8
Exosome-mediated Induction of Apoptosis in Cisplatin-treated GastricCancer Cells as a Strategy to Mitigate Side Effects	7
Hirsutanonol Inhibits the Progression of Hepatocellular Carcinoma by Promoting the Expression of CNDP1	7
COL10A1 as a Prognostic Biomarker in Association with Immune Infiltration in Prostate Cancer	7
The Imidazacridine Derivative LPSF/AC-05 Induces Apoptosis, Cell Cycle Arrest, and Topoisomerase II Inhibition in Breast Cancer, Leukemia, and Lymphoma	7
The Regulation of Ferroptosis by circRNAs in Various Cancers	7
Is the Use of SGLT-2 Associated with an Increased Risk of Cancer?	7
Silencing TRIM29 Sensitizes Non-small Cell Lung Cancer Cells to Anlotinib by Promoting Apoptosis via Binding RAD50	7
Assessing Long Non-coding RNAs in Tobacco-associated Oral Cancer	7
Coriandrum sativum and Aloysia triphylla can Protect the Development of Cancer: An in Vivo Study using Mouse Painting Assay	7
A Novel Platinum-Resistance-related Gene Signature in Ovarian Cancer: Identification and Patient-derived Organoids Verification	7
Pathological Implications of Mucin Signaling in Metastasis	7
Combinatorial Application of Papain and CD66B for Isolating Glioma- Associated Neutrophils	7
Elucidation of the Role of the Epigenetic Regulatory Mechanisms of PI3K/Akt/mTOR Signaling Pathway in Human Malignancies	7
Chimeric Antigen Receptor (CAR) T-cell Therapy: A New Genetically Engineered Method of Immunotherapy for Cancer	7
Exploring the Role of Long Non-Coding RNAs in Mediating Cisplatin Resistance in Colorectal Cancer	7
WEE Family Kinase Inhibitors Combined with Sorafenib Can Selectively Inhibit HCC Cell Proliferation	7
Advances and Future Prospects of Lipid-Based Nanocarriers in Targeted Cancer Therapy: A Comprehensive Review	7
YM155 Restores the Effect of Imatinib in Imatinib-Resistant Chronic Myeloid Leukemia Cell Lines	6
Combination Therapy with Androgen Receptor Pathway Inhibitors for Prostate Cancer	6
Exploration of the Synergistic Effect of Chitosan Oligosaccharide and Dacarbazine (DTIC) in the Treatment of Melanoma	6
Exploring the Impact of Chitosan-Based Nanoparticles in Cancer Targeted Drug Delivery: A Bibliometric Review	6
A Novel Oncogenic Role of Disulfidptosis-related Gene SLC7A11 in Anti-tumor Immunotherapy Response to Human Cancers	6
Dietary Flavonoids with Catechol Moiety Inhibit Anticancer Action of Bortezomib: What about the other Boronic Acid-based Drugs?	6
Silencing of FANCI Promotes DNA Damage and Sensitizes Ovarian Cancer Cells to Carboplatin	6
Comparison of Surgical and Colonoscopy Tissue to Establish Colorectal Patient-derived Organoids	6
Unveiling the Therapeutic Potential of Compounds Carrying Mono- and Bis-Thiazole Nuclei with Distinct Heterocyclic Analogues for Addressing Cancer Challenges	6
Tumor-Activated Neutrophils Promote Lung Cancer Progression through the IL-8/PD-L1 Pathway	6
Cuproptosis Related Gene DLD Associated with Poor Prognosis and Malignant Biological Characteristics in Lung Adenocarcinoma	6
Advances in Radiation Therapy Enhancement and Radio-Protection By Nano-Curcumins: A Systematic Review	6
mirna-383-5p Functions as an Anti-oncogene in Glioma through the Akt/mTOR Signaling Pathway by Targeting VEGFA	6
Repurposing of Antidiarrheal Loperamide for Treating Melanoma by Inducing Cell Apoptosis and Cell Metastasis Suppression In vitro and In vivo	6
L-lysine Increases the Anticancer Effect of Doxorubicin in Breast Cancer by Inducing ROS-dependent Autophagy	6
Integrative Deep Learning from H&E Images Reveals Prognostically Distinct Pathology-Based Subtypes in Bladder Cancer	6
RAD50 Deficient in a Breast Cancer Model Predicts Sensitivity to PARP Inhibitors	6
Controversial Role of Opioids: From Pain Control to Cancer Recurrence in Breast Cancer	6
Disulfiram-Copper Potentiates Anticancer Efficacy of Standard Chemotherapy Drugs in Bladder Cancer Animal Model through ROS-Autophagy-Ferroptosis Signalling Cascade	5
The Influence of KIR Gene Polymorphisms and KIR-ligand Binding on Outcomes in Hematologic Malignancies following Haploidentical Stem Cell Transplantation: A Comprehensive Review	5
Preface	5
Resistance of Lenvatinib in Hepatocellular Carcinoma	5
Machine Vision Approaches for Cervical Cancer Screening Using Pap-Smear Images: A Systematic Review	5
CDK Inhibition in Lung Cancer Alters Epithelial–Mesenchymal Transition, Autophagy, and Metabolism	5
Nanotechnological Advancements for the Theranostic Intervention in Anaplastic Thyroid Cancer: Current Perspectives and Future Direction	5
Molecular Targets and Nano-Technological Approaches in the Treatment of Hepatic Carcinoma	5
Downregulation of TIMP1 Promotes Ferroptosis and Suppresses Proliferation and Migration of Gastric Cancer Cells via Modulation of the PI3K/AKT Pathway	5
Unravelling the Mechanism of Methylophiopogonanone A Against Esophageal Squamous Cell Carcinoma Based on Network Pharmacology and Molecular Docking	5
Efficacy and Safety of Nimotuzumab in Combination with Radiotherapy or Chemoradiotherapy for Local Advanced Head and Neck Cancer: A Systematic Review and Meta-analysis	5
Forkhead Box Protein M1 (FOXM1): Prospective Prognostic Biomarker and Therapeutic Targets in Oral Cancer	5
Targeting Lactate Metabolism in Cancer Therapy: The Mechanism of Lactylation Modification and Prospects of Therapeutic Strategies	5
Phytochemicals as Promising Therapeutics in Cancer Prevention and Treatment: Mechanisms and Applications	5
Angiogenesis and Pancreatic Cancer: Novel Approaches to Overcome Treatment Resistance	5
ZIP14 Affects the Proliferation, Apoptosis, and Migration of Cervical Cancer Cells by Regulating the P38 MAPK Pathway	5
Targeting the Tumor Epigenetic Regulator SETDB1 for Tumor Therapy	5
Combined Immunotherapy and Targeted Therapies for Cancer Treatment: Recent Advances and Future Perspectives	5
IR-780 Dye-based Targeting of Cancer-associated Fibroblasts Improves Cancer Immunotherapy by Increasing Intra-tumoral T Lymphocytes Infiltration	5
VX-765 has a Protective Effect on Mice with Ovarian Injury Caused by Chemotherapy	5
Present and Future Prospects of the Anti-cancer Activities of Saikosaponins	5
The Clinical Role of Hypoxia Inducible Factor (HIF) Inhibition in Renal Cancer: A Focus on Belzutifan	5
Research Progress of Neural Invasion in Pancreatic Cancer	5
Research Advances of Clinical Application of Oncolytic Viruses in Treatment of Gynecologic Cancers	5
ADH1B Gene Promotes Gastric Cancer Tumorigenesis and its Cisplatin Resistance through the EMT Pathway	5
UCA1 Inhibits NKG2D-mediated Cytotoxicity of NK Cells to Breast Cancer	5
The Effects of Mesenchymal Stem Cells Loaded with Oncolytic Coxsackievirus A21 on Mouse Models of Colorectal Cancer	5
Therapy-Induced Cellular Senescence in Non-Hodgkin Lymphomas, with Emphasis on Aggressive B-Cell Subtypes: Molecular Mechanisms and Emerging Drug Targets	4
Raddeanoside R13 Inhibits Proliferation, Invasion, and Metastasis of Gastric Cancer Cells Based on Network Pharmacology and Experimental Validation	4
Homoharringtonine Impedes Migration and Invasion by Inhibiting EphB4/SRI/EMT Signaling and Enhances the Antimetastatic Abilities of Erlotinib in Pancreatic Cancer	4
Comprehensive Pan-cancer Analysis and Experimental Verification of EGLN Family: Potential Biomarkers in Cervical Cancer	4
The Prognostic Value and Clinical Significance of lncRNA SNHG5 Expression in Patients with Multiple Malignancies: A Bioinformatic and Meta-analysis	4
The Association between NADPH Oxidase 2 (NOX2) and Drug Resistance in Cancer	4
Up-regulation of Core 1 Beta 1, 3-Galactosyltransferase Suppresses Osteosarcoma Growth with Induction of IFN-γ Secretion and Proliferation of CD8+ T Cells	4
Recent Progress in the Application of Exosome Analysis in Ovarian Cancer Management	4
Sildenafil Inhibits the Growth and Epithelial-to-mesenchymal Transition of Cervical Cancer via the TGF-β1/Smad2/3 Pathway	4
Perspectives on Ergodic Cancer Therapy Derived from Cloning Genome Chaos via In Vivo Rhabdomyosarcoma RA-2 Models: a Narrative Review	4
GAPVD1 Promotes the Proliferation of Triple-negative Breast Cancer Cells by Regulating the ERK/MAPK Signaling Pathway	4
Traditional Chinese Medicine Targeting Sarcoma Virus Oncogene-related Diseases	4
Εmerging Biomarkers in the Diagnosis and Treatment of Testicular Tumors	4
AAV-HOTAIR Delivery in Colorectal Cancer Cells: Preliminary Insights into Gene Silencing and Epigenetic Influences	4
GPX4 Inhibition Enhances the Antitumor Effect of PARP Inhibitor on Homologous Recombination Proficient Ovarian Cancer Cells	4
Dihydrotanshinone I Inhibits Pancreatic Cancer Progression via Hedgehog/ Gli Signal Pathway	4

Smart Nanobiomaterials for Gene Delivery in Localized Cancer Therapy: An Overview from Emerging Materials and Devices to Clinical Applications	4
Preface	4
Research Progress on Immunotherapy Targets in Nasopharyngeal Carcinoma	4
LncRNA ABCA9-AS1 as a ceRNA Promotes Gastric Cancer Progression by Sponging miR-497-5p to Regulate KIF23 Expression	4
Insights into the Emerging Therapeutic Targets of Triple-negative Breast Cancer	4
Study on Cellular Localization of Bin Toxin and its Apoptosis-inducing Effect on Human Nasopharyngeal Carcinoma Cells	4
Comprehensive Analysis Identifies Tumor Mutation Burden-associated Genes ASPM and KIF11 as Novel Biomarkers for Adrenocortical Carcinoma	4
The Thorny Question of Early Diagnosis in Lung Cancer: Should the IP-10 Cytokine be Brought to Trial?	4
Clinicopathological, Immunohistochemical, and Molecular Genetic Study on Pleomorphic Xanthoastrocytoma and Epithelioid Glioblastoma	4
Recent Advances in Kinase Targeting for Hepatocellular Carcinoma: Emerging Strategies and Clinical Insights	4
The Role of Local Angiotensin II/Angiotensin Type 1-receptor Mechanisms in Adipose Tissue Dysfunction to Promote Pancreatic Cancer	4
AHNAK2 Promotes the Progression of Differentiated Thyroid Cancer through PI3K/AKT Signaling Pathway	4
Mitochondrial Calcium Uniporter (MCU) that Modulates Mitochondrial Calcium Uptake and Facilitates Endometrial Cancer Progression through Interaction with VDAC1	4
LINC00887 Acts as an Enhancer RNA to Promote Medullary Thyroid Carcinoma Progression by Binding with FOXQ1	3
Gastroenteropancreatic Neuroendocrine Neoplasms (GEP NENs): The Role of Checkpoint Inhibitors	3
Exploration of the Values of Macrophage Differentiation-Related Genes in Prognosis and Immunotherapy Prediction for Hepatocellular Carcinoma	3
Advancements in Phytosomal Therapies for Liver Cancer: A Comprehensive Review	3
GOLM1-induced Vascular Permeability and Angiogenesis in Hepatocellular Carcinoma through Modulation of Cancer Cell-derived Exosomal microRNAs	3
Current Perspectives in Ultra-sensitive Detection of Cancer-specific Biomarkers and Therapeutic Targets	3
Exosomes Mediate the Production of Oxaliplatin Resistance and Affect Biological Behaviors of Colon Cancer Cell Lines	3
Spatial Analysis of FAP Gene Expression in Breast Cancer	3
H3K27ac-activated LncRNA NUTM2A-AS1 Facilitated the Progression of Colorectal Cancer Cells via MicroRNA-126-5p/FAM3C Axis	3
Prospective Clinical and Biochemical Evaluation of Breast Cancer in Patient Cohorts	3
Grafting of Resveratrol-Chitosan Nanoparticles as a Promising Radiosensitizer and Protector in DMBA-Induced Breast Cancer in Mice	3
Transformative Advances in the Treatment of Melanoma: A Review	3
Deubiquitylase USP31 Induces Autophagy and Promotes the Progression in Lung Squamous Cell Carcinoma Cells by Stabilizing E2F1 Expression	3
miRNAs as Theragnostic Markers for PARP Inhibitor Resistance in Breast Cancer: A Systematic Review	3
WITHDRAWN: Network Pharmacology and In vitro Experiments Reveal that Noscapine Induces Ros-mediated Apoptosis and Cell Cycle Arrest via PI3K/Akt/FoxO3a Signaling Pathway in Human Bladder Cancer Cells	3
The Role of Oxidative Stress in the Development and Therapeutic Intervention of Hepatocellular Carcinoma	3
Effects of HSV-G47Δ Oncolytic Virus on Telomerase and Telomere Length Alterations in Glioblastoma Multiforme Cancer Stem Cells Under Hypoxia and Normoxia Conditions	3
Comparing Cisplatin Sensitivity in Conventional 2D Versus Biomaterialfree 3D Spheroid Cultures of Human Cancer and Bone Marrow Stromal Cells	3
Mitochondrial Dynamics as Determinants of Cancer Drug Resistance: A Systematic Review	3
Embracing the Circular Journey of RNA in Colorectal Cancer	3
IL-33/ST2 Signaling and its Correlation with Macrophage Heterogeneity and Clinicopathologic Features in Human Intrahepatic Cholangiocarcinoma	3
Role of Non-Coding RNAs in Regulating PD-L1 Expression in Breast Cancer: Emerging Insights and Implications	3
Clinical Efficacy and Safety of Anlotinib Combined with Immune Checkpoint Inhibitors in the Treatment of Advanced Squamous Cell Lung Cancer: A Retrospective Single-Center Study in China	3
EVI5 Drives Lung Adenocarcinoma Progression through Modulation of the ERK1/2-c-Myc Signaling Axis	3
Dysregulated Epigenetics of Chordoma: Prognostic Markers and Therapeutic Targets	3
Exploring the Tumor Microenvironment: Immuno-Genotoxic Biomarkers at the Forefront of Cancer Diagnosis and Therapy	3
CT109-SN-38, a Novel Antibody-drug Conjugate with Dual Specificity for CEACAM5 and 6, Elicits Potent Killing of Pancreatic Cancer Cells	3
WITHDRAWN: Comprehensive Analysis of the Role of CXCL Family Members in Clear Cell Renal Cell Carcinoma	3
EGFR and ALK Targeted Therapy Response in Non-Small Cell Lung Cancer Harboring Rare or Resistant Mutations: A Case Report and Molecular Insights	3
CircRNAs Regulate Senescence-Associated miRNAs in Gastric Cancer	3
Mechanistic Insights into Targeting the Ovarian Cancer Stem Cell Microenvironment: A Review of Therapeutic Strategies	3
Comprehensive Immune Subtyping and Multi-Omics Profiling of the Tumor Microenvironment in Colorectal Cancer: Implications for Prognosis and Personalized Immunotherapy	3
RC48 Induces Senescence in HER2-Expressing Colon Cancer Cells by Activating the CDKN1A-RB-E2F1 Pathway	3
DTL is a Novel Downstream Gene of E2F1 that Promotes the Progression of Hepatocellular Carcinoma	3
Shared Genetic Architecture of Epilepsy and Glioma Revealed by Mendelian Randomization: Identifying Prognostic Biomarkers and Therapeutic Targets	3
Corrigendum to: Low Expression MCEMP1 Promotes Lung Adenocarcinoma Progression and its Clinical Value	3
Corrigendum to: High Glucose and Glucose-derived Intermediates are Linked to Lung Cancer Aggressiveness	3
A Pan-cancer Analysis to Determine the Prognostic Analysis and Immune Infiltration of HSPA5	3
Probiotics as a Therapeutic Approach in Colorectal Cancer	3
Mechanism of Bispecific Antibodies and Clinical Research Advances in Lung Cancer	3
Netupitant-palonosetron (NEPA) for Preventing Chemotherapy-induced Nausea and Vomiting: From Clinical Trials to Daily Practice	3
Extraordinary Benefit of Regorafenib in Metastatic Cholangiocarcinoma: A Case Report	2
Exosomal circRNAs: The Key Role and Potential Therapeutic Target in Gastric Cancer	2
Elucidating the Role of Pro-renin Receptors in Pancreatic Ductal Adenocarcinoma Progression: A Novel Therapeutic Target in Cancer Therapy	2
Future Management of Chronic Myeloid Leukemia: From Dose Optimization to New Agents	2
Phosphoserine Aminotransferase 1: A Metabolic Enzyme Target of Cancers	2
Envafolimab Inhibits the Growth of Gastric Cancer Cells with Low PD-L1 Expression through the DDX20/NF-κB/TNF-α Signaling Pathway	2
Cucurbitacin D Inhibits the Proliferation of HepG2 Cells and Induces Apoptosis by Modulating JAK/STAT3, PI3K/Akt/mTOR and MAPK Signaling Pathways	2
Construction of an Oxidative Stress Risk Model to Analyze the Correlation Between Liver Cancer and Tumor Immunity	2
Decoding Metastasis: From Cell Death to Fusion in Cancer Progression	2
The Role of Lactate in Cancer Immunotherapy: Mechanisms and Applications	2
Arsenic Trioxide Restrains Lung Cancer Growth and Metastasis by Blocking the Calcineurin-NFAT Pathway by Upregulating DSCR1	2
Impact of GSTT1 and GSTM1 Polymorphisms in the Susceptibility to Philadelphia Negative Chronic Myeloid Leukaemia	2
Inhibitor of Growth 4 (ING4) Plays a Tumor-repressing Role in Oral Squamous Cell Carcinoma via Nuclear Factor Kappa-B (NF-kB)/DNA Methyltransferase 1 (DNMT1) Axis-mediated Regulation of Aldehyde Dehyd	2
CXCR4 Facilitates Osteosarcoma Progression through MMP9-Mediated Cell Migration and Matrix Degradation	2
An Overview of the Dichotomous Role of Microbiota in Cancer Progression and Management	2
BZW2, CDT1 and IVD Act As Biomarkers for Predicting Hepatocellular Carcinoma	2
Low Expression of GRIM-19 Correlates with Poor Prognosis in Patients with Upper Urinary Tract Urothelial Carcinoma	2
Role of Immunotherapy in the Management of Advanced Hepatocellular Carcinoma: A Systematic Review	2
Naringenin-induced Oral Cancer Cell Apoptosis Via ROS-mediated Bid and Bcl-xl Signaling Pathway	2
Treatment Advances in Lung Cancer with Leptomeningeal Metastasis	2
The Function of PPARα in Cancer Drug Development: A Promising Target for Cancer Treatment	2
The Role of pAHSG in Omental Metastasis of Ovarian Cancer: A New Perspective on Treatment	2
Geiparvarin Inhibits the Progression of Osteosarcoma by Down-regulating COX2 Expression	2
PIWIL1 Promotes Malignant Progression of Papillary Thyroid Carcinoma by Inducing EVA1A Expression	2
EWS-RNA Binding Protein 1: Structural Insights into Ewing Sarcoma by Conformational Dynamics Investigations	2
Saikosaponin B4 Suppression Cancer Progression by Inhibiting SW480 and SW620 Cells Proliferation via the PI3K/AKT/mTOR Pathway in Colon Cancer	2
The Clinicopathological and Prognostic Significance of the Expression of PD-L1 and MET Genes in Breast Cancer: Potential Therapeutic Targets	2
SPON2 Suppresses Autophagy by Regulating the PI3K/AKT/mTOR Signaling Pathway in Renal Cell Carcinoma	2
The HGF/Met Receptor Mediates Cytotoxic Effect of Bacterial Cyclodipeptides in Human Cervical Cancer Cells	2
Identification of Necroptosis-related Subtypes and Characterization of Tumor Microenvironment Infiltration in Non-small Cell Lung Cancer	2
Promotion of Melanoma Progression through MCM4-Induced Immune Suppression and Polarization of Macrophages by Carcinogenic Exosomes	2
Reimagining Renal Cell Carcinoma Therapy: Bridging Conventional Gaps with Monoclonal Antibodies (mAbs), Tyrosine Kinase Inhibitors (nibs), and Nanocarriers	2
The Tumor Immune Microenvironment plays a Key Role in Driving the Progression of Cholangiocarcinoma	2
Corrigendum to: GPX4 Inhibition Enhances the Antitumor Effect of PARP Inhibitor on Homologous Recombination Proficient Ovarian Cancer Cells	2
Value of Label-Free Ubiquitin-Proteomic Analysis on Defining the Protective Mechanism of Valsartan against Doxorubicin-Induced Heart Failure	2
MND1 Promotes the Proliferation of Prostate Cancer Cell Via the CCNB1/p53 Signaling Pathway	2
Cisplatin Kills Ovarian Cancer Cells by Causing Mitochondrial Oxidative Stress and Death Through the TRPV1 Channel Stimulation: The Role of Eicosapentaenoic Acid	2
Effect of HPV Oncoprotein on Carbohydrate and Lipid Metabolism in Tumor Cells	2
Functional Characterization and Prognostic Value of PIAS Family Genes in Liver Hepatocellular Carcinoma	2
Antibody-Drug Conjugates (ADCs): A Novel Therapy for Triple-Negative Breast Cancer (TNBC)	2
Novel Synergistic Combination of Pamidronate and Temozolomide for Breast Cancer Therapeutics	2