Current Cancer Drug Targets

Article	Citations
The Expression of Glutaminases and their Association with Clinicopathological Parameters in the Head and Neck Cancers	86
Micro-fragmented Fat Inhibits the Progression of Human Mesothelioma Xenografts in Mice	45
FHOD3 Promotes the Progression of Lung Cancer by Regulating the Caspase-3-Mediated Signaling Pathway	41
A Review on Patient-derived 3D Micro Cancer Approach for Drug Screen in Personalized Cancer Medicine	37
Progress in Metabolic Studies of Gastric Cancer and Therapeutic Implications	34
Etiology-based Molecular Characterization of Hepatocellular Carcinoma Reveals SQLE's Contribution to Immunosuppressive Microenvironment	27
A Pilot Study of Anlotinib as a Combination Treatment in Advanced Nasopharyngeal Carcinoma	26
Knockdown of PRKD2 Enhances Chemotherapy Sensitivity in Cervical Cancer via the TP53/CDKN1A Pathway	26
TBOPP, a DOCK1 Inhibitor, Potentiates Cisplatin Efficacy in Breast Cancer by Regulating Twist-mediated EMT	26
Expression, Prognostic Value, and Immune Infiltration of MTHFD Family in Bladder Cancer	25
Silencing HEATR1 Rescues Cisplatin Resistance of Non-small Cell Lung Cancer by Inducing Ferroptosis via the p53/SAT1/ALOX15 Axis	23
LMNB1/CDKN1A Signaling Regulates the Cell Cycle and Promotes Hepatocellular Carcinoma Progression	18
Unveiling Novel Therapeutic Drug Targets and Prognostic Markers of Triple Negative Breast Cancer	16
Efficacy and Safety of Immunotherapy Combined with Anlotinib as First-Line Treatment in Older NSCLC Patients with PD-L1 Expression<50%	16
Immune Checkpoint Inhibitors for Advanced Biliary Tract Cancer	14
Development of Chromatin Regulator-related Molecular Subtypes and a Signature to Predict Prognosis and Immunotherapeutic Response in Head and Neck Squamous Cell Carcinoma	14
Spinal KCC2 Mediates the Modulation Effect of HDAC2 on Bone Cancer Pain in Rats	14
Combined RNAi of CTTN and FGF2 Modulates Cell Migration, Invasion and G1/S Transition of Hepatocellular Carcinoma through Ras/ERK Signaling Pathway	14
Bioinformatics and Experimental Study Revealed LINC00982/ miR-183-5p/ABCA8 Axis Suppresses LUAD Progression	14
The Therapeutic Potential of Urolithin A for Cancer Treatment and Prevention	14
Identification of ATM Mutation as a Potential Prognostic Biomarker for Immune Checkpoint Inhibitors Therapy	14
Inorganic Phosphate (Pi) in the Breast Cancer Microenvironment: Production, Transport and Signal Transduction as Potential Targets for Anticancer Strategies	13
PLCG2, A Regulator of Lung Adenocarcinoma Proliferation and Migration Associated with Immune Infiltration	13
Review Deciphering the Potential of Nanotherapeutics in Lung Cancer Management	13
High Expression of PKMYT1 Predicts Poor Prognosis and Aggravates the Progression of Osteosarcoma via the NF-κB Pathway in MG63 Cells	13

MMP7, Regulated by c-Jun, is Involved in Oral Squamous Cell Carcinoma and Associated with Cancer-Related Fibroblasts Infiltration	13
LINC00461 Knockdown Enhances the Effect of Ixazomib in Multiple Myeloma Cells	13
Role of Natural Nuclear Factor Erythroid-2-related Factor 2 (Nrf2) Activators in Oral and Head and Neck Cancer Treatment	13
Downregulation of CCKBR Expression Inhibits the Proliferation of Gastric Cancer Cells, Revealing a Potential Target for Immunotoxin Therapy	12
A Molecular Link Between Diabetes and Breast Cancer: Therapeutic Potential of Repurposing Incretin-based Therapies for Breast Cancer	12
Low Expression of SCN4B Predicts Poor Prognosis in Non-small Cell Lung Cancer	12
WITHDRAWN: Use of Tumor-Infiltrating Lymphocyte (TIL) Cell Therapy for Spindle Cell Carcinoma of the Breast: A Case Report	12
Targeting the HIF-1α/Cav-1 Pathway with a Chicory Extract/Daidzein Combination Plays a Potential Role in Retarding Hepatocellular Carcinoma	11
Epigallocatechin-3-gallate Induced HepG2 Cells Apoptosis through ROSmediated AKT /JNK and p53 Signaling Pathway	11
EGF/EGFR Promotes Salivary Adenoid Cystic Carcinoma Cell Malignant Neural Invasion via Activation of PI3K/AKT and MEK/ERK Signaling	11
Identification of AHSA1 as a Potential Therapeutic Target for Breast Cancer: Bioinformatics Analysis and in vitro Studies	10
Nanodiamond Mediated Molecular Targeting in Pancreatic Ductal Adenocarcinoma: Disrupting the Tumor-stromal Cross-talk, Next Hope on the Horizon?	10
An Updated Review on Molecular Biomarkers in Diagnosis and Therapy of Colorectal Cancer	10
Transcription Factor MAZ Potentiates the Upregulated NEIL3-mediated Aerobic Glycolysis, thereby Promoting Angiogenesis in Hepatocellular Carcinoma	10
Real-world Study on the Effect of PARPi as Maintenance Therapy on Platinum Sensitivity after First- and Second-line Chemotherapy in Patients with Recurrent High-grade Serous Epithelial Ovarian Cancer	9
Angiotensin-converting Enzyme Inhibitors and Angiotensin Receptor Blockers as Potential Therapeutic Options for Pancreatic Cancer	9
Utilization of DNA Replication factor MCM2 by Cancer	9
Anti-breast Cancer Potential of Prosopis cineraria L. Phytocompounds: A Network Pharmacology and in vitro Analysisbased Approach	9
Comprehensive Pan-cancer Analysis of CMPK2 as Biomarker and Prognostic Indicator for Immunotherapy	9
Withaferin A Inhibits Liver Cancer Tumorigenesis by Suppressing Aerobic Glycolysis through the p53/IDH1/HIF-1α Signaling Axis	9
Preventive and Therapeutic effects of Metformin in Cancer: A Meta-Analysis of RCT and Cohort Studies	9
Elucidating the Potential of E-cadherin Re-expression along with Trichostatin A and Zebularine in Enhancing Tumour Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)-Induced Apoptosis in Human	9
Solid CaCO3 Formation in Glioblastoma Multiforme and its Treatment with Ultra-Nanoparticulated NPt-Bionanocatalysts	9
Protein Tyrosine Phosphatase 1B (PTP1B): Insights into its New Implications in Tumorigenesis	9
WITHDRAWN: Hidrosmin Attenuates Inflammatory Response Induced by IL1β by Suppressing the Activation of NF-κB Involving Nrf2/HO1Pathway in Human Osteoarthritis Chondrocytes	9
Stabilizing Scaffold for Short Peptides Based on Knottins	8
Twenty-four-month Progression-free Survival in HER2-amplified Advanced Gastric Cancer with Brain Metastases after Trastuzumab Deruxtecan Treatment: A Case Report and Literature Review	8
Screening miRNAs to Hinder the Tumorigenesis of Renal Clear Cell Carcinoma Associated with KDR Expression	8
CEA-regulated Oncolytic Virus Anticancer Therapy: A Promising Strategy for Rare Solid Tumors	8
Curcumin Inhibits Vasculogenic Mimicry via Regulating ETS-1 in Renal Cell Carcinoma	8
Cancer Vaccine in Cold Tumors: Clinical Landscape, Challenges, and Opportunities	8
Gender Matters. Sex-related Differences in Immunotherapy Outcome in Patients with Non-small Cell Lung Cancer	8
A Saffron-based Polyherbal Formulation DuK Prevents Hepatocellular Carcinoma in Male Wistar Rats	8
FA-HA-Amygdalin@Fe2O3 and/or γ-Rays Affecting SIRT1 Regulation of YAP/TAZ-p53 Signaling and Modulates Tumorigenicity of MDA-MB231 or MCF-7 Cancer Cells	8
Long Non-Coding RNA HCP5 Affects Ferroptosis in Lung Adenocarcinoma through miR-17-5p/HOXA7 Axis	8
Promotion of Cervical Cancer Cell Proliferation by miR-130b Expression Level Changes and Inhibition of its Apoptosis by Targeting CDKN1A Gene	8
HIF-1α/Malat1/miR-141 Axis Activates Autophagy to Increase Proliferation, Migration, and Invasion in Triple-negative Breast Cancer	7
Efficacy and Safety of Phosphatidylinositol 3-kinase Inhibitors for Patients with Breast Cancer: A Systematic Review and Meta-analysis of Randomized Controlled Trials	7
Advances and Future Prospects of Lipid-Based Nanocarriers in Targeted Cancer Therapy: A Comprehensive Review	7
Autophagy in Cancer Cell Transformation: A Potential Novel Therapeutic Strategy	7
CDK8 as a therapeutic target for overall survival prediction in cervical squamous cell carcinoma (CESC)	7
Precision Medicine in Colorectal Cancer: Targeted Therapies and Biomarker Insights	7
Neuronatin Promotes the Progression of Non-small Cell Lung Cancer by Activating the NF-κB Signaling	7
Recent Advancements in Drug Targeting for Ferroptosis as an Antitumor Therapy: Development of Novel therapeutics	7
Elucidation of the Role of the Epigenetic Regulatory Mechanisms of PI3K/Akt/mTOR Signaling Pathway in Human Malignancies	7
COL10A1 as a Prognostic Biomarker in Association with Immune Infiltration in Prostate Cancer	7
RON Receptor Tyrosine Kinase in Tumorigenic Stemness as a Therapeutic Target of Antibody-drug Conjugates for Eradication of Triple-negative Breast Cancer Stem Cells	7
Progressive Dynamics of Cancer Stem Cells in Oral Squamous Cell Carcinoma	7
Spleen Glucose Metabolism on [18F]-FDG PET/CT for Cancer Drug Discovery and Development cannot be Overlooked	7
TROP2 Down-regulated DSG2 to Promote Gastric Cancer Cell Invasion and Migration by EGFR/AKT and DSG2/PG/β-Catenin Pathways	7

Pathological Implications of Mucin Signaling in Metastasis	7
Combinatorial Application of Papain and CD66B for Isolating Glioma- Associated Neutrophils	7
Silencing TRIM29 Sensitizes Non-small Cell Lung Cancer Cells to Anlotinib by Promoting Apoptosis via Binding RAD50	7
Targeting Glutamine Metabolic Reprogramming in Pancreatic Cancer: Current Insights and Future Directions	7
Combination Therapy with Androgen Receptor Pathway Inhibitors for Prostate Cancer	6
Current Challenges in Targeting Tumor Desmoplasia to Improve the Efficacy of Immunotherapy	6
Repurposing of Antidiarrheal Loperamide for Treating Melanoma by Inducing Cell Apoptosis and Cell Metastasis Suppression In vitro and In vivo	6
mirna-383-5p Functions as an Anti-oncogene in Glioma through the Akt/mTOR Signaling Pathway by Targeting VEGFA	6
Tumor-Activated Neutrophils Promote Lung Cancer Progression through the IL-8/PD-L1 Pathway	6
Exploring the Role of Long Non-Coding RNAs in Mediating Cisplatin Resistance in Colorectal Cancer	6
Comparison of Surgical and Colonoscopy Tissue to Establish Colorectal Patient-derived Organoids	6
Chimeric Antigen Receptor (CAR) T-cell Therapy: A New Genetically Engineered Method of Immunotherapy for Cancer	6
L-lysine Increases the Anticancer Effect of Doxorubicin in Breast Cancer by Inducing ROS-dependent Autophagy	6
Assessing Long Non-coding RNAs in Tobacco-associated Oral Cancer	6
Unveiling the Therapeutic Potential of Compounds Carrying Mono- and Bis-Thiazole Nuclei with Distinct Heterocyclic Analogues for Addressing Cancer Challenges	6
WEE Family Kinase Inhibitors Combined with Sorafenib Can Selectively Inhibit HCC Cell Proliferation	6
Coriandrum sativum and Aloysia triphylla can Protect the Development of Cancer: An in Vivo Study using Mouse Painting Assay	6
Controversial Role of Opioids: From Pain Control to Cancer Recurrence in Breast Cancer	6
Silencing of FANCI Promotes DNA Damage and Sensitizes Ovarian Cancer Cells to Carboplatin	6
A Novel Oncogenic Role of Disulfidptosis-related Gene SLC7A11 in Anti-tumor Immunotherapy Response to Human Cancers	6
The Imidazacridine Derivative LPSF/AC-05 Induces Apoptosis, Cell Cycle Arrest, and Topoisomerase II Inhibition in Breast Cancer, Leukemia, and Lymphoma	6
Is the Use of SGLT-2 Associated with an Increased Risk of Cancer?	6
Exosome-mediated Induction of Apoptosis in Cisplatin-treated GastricCancer Cells as a Strategy to Mitigate Side Effects	6
Cuproptosis Related Gene DLD Associated with Poor Prognosis and Malignant Biological Characteristics in Lung Adenocarcinoma	5
Nanotechnological Advancements for the Theranostic Intervention in Anaplastic Thyroid Cancer: Current Perspectives and Future Direction	5
Dietary Flavonoids with Catechol Moiety Inhibit Anticancer Action of Bortezomib: What about the other Boronic Acid-based Drugs?	5
Antibody-drug Conjugate Targets, Drugs, and Linkers	5
Research Progress of Neural Invasion in Pancreatic Cancer	5
Advances in Radiation Therapy Enhancement and Radio-Protection By Nano-Curcumins: A Systematic Review	5
RAD50 Deficient in a Breast Cancer Model Predicts Sensitivity to PARP Inhibitors	5
Angiogenesis and Pancreatic Cancer: Novel Approaches to Overcome Treatment Resistance	5
Targeting the Tumor Epigenetic Regulator SETDB1 for Tumor Therapy	5
IR-780 Dye-based Targeting of Cancer-associated Fibroblasts Improves Cancer Immunotherapy by Increasing Intra-tumoral T Lymphocytes Infiltration	5
ZIP14 Affects the Proliferation, Apoptosis, and Migration of Cervical Cancer Cells by Regulating the P38 MAPK Pathway	5
Resistance of Lenvatinib in Hepatocellular Carcinoma	5
The Effects of Mesenchymal Stem Cells Loaded with Oncolytic Coxsackievirus A21 on Mouse Models of Colorectal Cancer	5
UCA1 Inhibits NKG2D-mediated Cytotoxicity of NK Cells to Breast Cancer	5
Research Advances of Clinical Application of Oncolytic Viruses in Treatment of Gynecologic Cancers	5
YM155 Restores the Effect of Imatinib in Imatinib-Resistant Chronic Myeloid Leukemia Cell Lines	5
Forkhead Box Protein M1 (FOXM1): Prospective Prognostic Biomarker and Therapeutic Targets in Oral Cancer	5
ADH1B Gene Promotes Gastric Cancer Tumorigenesis and its Cisplatin Resistance through the EMT Pathway	5
Preface	4
Disulfiram-Copper Potentiates Anticancer Efficacy of Standard Chemotherapy Drugs in Bladder Cancer Animal Model through ROS-Autophagy-Ferroptosis Signalling Cascade	4
Sildenafil Inhibits the Growth and Epithelial-to-mesenchymal Transition of Cervical Cancer via the TGF-β1/Smad2/3 Pathway	4
Efficacy and Safety of Nimotuzumab in Combination with Radiotherapy or Chemoradiotherapy for Local Advanced Head and Neck Cancer: A Systematic Review and Meta-analysis	4
Polyphyllin VII is a Potential Drug Targeting CD44 Positive Colon Cancer Cells	4
Up-regulation of Core 1 Beta 1, 3-Galactosyltransferase Suppresses Osteosarcoma Growth with Induction of IFN-γ Secretion and Proliferation of CD8+ T Cells	4
GPX4 Inhibition Enhances the Antitumor Effect of PARP Inhibitor on Homologous Recombination Proficient Ovarian Cancer Cells	4
GAPVD1 Promotes the Proliferation of Triple-negative Breast Cancer Cells by Regulating the ERK/MAPK Signaling Pathway	4
Smart Nanobiomaterials for Gene Delivery in Localized Cancer Therapy: An Overview from Emerging Materials and Devices to Clinical Applications	4
Εmerging Biomarkers in the Diagnosis and Treatment of Testicular Tumors	4
Preface	4
AHNAK2 Promotes the Progression of Differentiated Thyroid Cancer through PI3K/AKT Signaling Pathway	4
Unravelling the Mechanism of Methylophiopogonanone A Against Esophageal Squamous Cell Carcinoma Based on Network Pharmacology and Molecular Docking	4
VX-765 has a Protective Effect on Mice with Ovarian Injury Caused by Chemotherapy	4
Durable Disease-free Survival in a Patient with Metastatic Triple-negative Breast Cancer Treated with Olaparib Monotherapy	4
The Association between NADPH Oxidase 2 (NOX2) and Drug Resistance in Cancer	4
Metastatic Breast Cancer, Organotropism and Therapeutics: A Review	4
Comprehensive Pan-cancer Analysis and Experimental Verification of EGLN Family: Potential Biomarkers in Cervical Cancer	4
Insights into the Emerging Therapeutic Targets of Triple-negative Breast Cancer	4
Mitochondrial Calcium Uniporter (MCU) that Modulates Mitochondrial Calcium Uptake and Facilitates Endometrial Cancer Progression through Interaction with VDAC1	4
Combined Immunotherapy and Targeted Therapies for Cancer Treatment: Recent Advances and Future Perspectives	4
Present and Future Prospects of the Anti-cancer Activities of Saikosaponins	4
The Influence of KIR Gene Polymorphisms and KIR-ligand Binding on Outcomes in Hematologic Malignancies following Haploidentical Stem Cell Transplantation: A Comprehensive Review	4
The Role of Local Angiotensin II/Angiotensin Type 1-receptor Mechanisms in Adipose Tissue Dysfunction to Promote Pancreatic Cancer	4
Dihydrotanshinone I Inhibits Pancreatic Cancer Progression via Hedgehog/ Gli Signal Pathway	4
Study on Cellular Localization of Bin Toxin and its Apoptosis-inducing Effect on Human Nasopharyngeal Carcinoma Cells	4
Modifications of Ribonucleases in Order to Enhance Cytotoxicity in Anticancer Therapy	4
The Prognostic Value and Clinical Significance of lncRNA SNHG5 Expression in Patients with Multiple Malignancies: A Bioinformatic and Meta-analysis	4
Recent Progress in the Application of Exosome Analysis in Ovarian Cancer Management	4
The Therapeutic Potential of MAPK/ERK Inhibitors in the Treatment of Colorectal Cancer	3
The Role of Oxidative Stress in the Development and Therapeutic Intervention of Hepatocellular Carcinoma	3
Dextran Sulfate Inhibits Cell Proliferation and Induces Apoptosis by Regulating EZH2 in Gastric Carcinoma	3
Comprehensive Immune Subtyping and Multi-Omics Profiling of the Tumor Microenvironment in Colorectal Cancer: Implications for Prognosis and Personalized Immunotherapy	3
Raddeanoside R13 Inhibits Proliferation, Invasion, and Metastasis of Gastric Cancer Cells Based on Network Pharmacology and Experimental Validation	3
Current Perspectives in Ultra-sensitive Detection of Cancer-specific Biomarkers and Therapeutic Targets	3
CircRNAs Regulate Senescence-Associated miRNAs in Gastric Cancer	3
CT109-SN-38, a Novel Antibody-drug Conjugate with Dual Specificity for CEACAM5 and 6, Elicits Potent Killing of Pancreatic Cancer Cells	3
Role of Non-Coding RNAs in Regulating PD-L1 Expression in Breast Cancer: Emerging Insights and Implications	3
Grafting of Resveratrol-Chitosan Nanoparticles as a Promising Radiosensitizer and Protector in DMBA-Induced Breast Cancer in Mice	3

Corrigendum to: Low Expression MCEMP1 Promotes Lung Adenocarcinoma Progression and its Clinical Value	3
Deubiquitylase USP31 Induces Autophagy and Promotes the Progression in Lung Squamous Cell Carcinoma Cells by Stabilizing E2F1 Expression	3
H3K27ac-activated LncRNA NUTM2A-AS1 Facilitated the Progression of Colorectal Cancer Cells via MicroRNA-126-5p/FAM3C Axis	3
Experimental Determination of Cancer Drug Targets with Independent Mechanisms of Resistance	3
Traditional Chinese Medicine Targeting Sarcoma Virus Oncogene-related Diseases	3
Effects of HSV-G47Δ Oncolytic Virus on Telomerase and Telomere Length Alterations in Glioblastoma Multiforme Cancer Stem Cells Under Hypoxia and Normoxia Conditions	3
Embracing the Circular Journey of RNA in Colorectal Cancer	3
Emerging Prospects for the Study of Colorectal Cancer Stem Cells using Patient-derived Organoids	3
The Potential of Natural Products in the Treatment of Triple-negative Breast Cancer	3
GOLM1-induced Vascular Permeability and Angiogenesis in Hepatocellular Carcinoma through Modulation of Cancer Cell-derived Exosomal microRNAs	3
IL-33/ST2 Signaling and its Correlation with Macrophage Heterogeneity and Clinicopathologic Features in Human Intrahepatic Cholangiocarcinoma	3
Probiotics as a Therapeutic Approach in Colorectal Cancer	3
Gastroenteropancreatic Neuroendocrine Neoplasms (GEP NENs): The Role of Checkpoint Inhibitors	3
LINC00887 Acts as an Enhancer RNA to Promote Medullary Thyroid Carcinoma Progression by Binding with FOXQ1	3
RC48 Induces Senescence in HER2-Expressing Colon Cancer Cells by Activating the CDKN1A-RB-E2F1 Pathway	3
Netupitant-palonosetron (NEPA) for Preventing Chemotherapy-induced Nausea and Vomiting: From Clinical Trials to Daily Practice	3
Advancements in Phytosomal Therapies for Liver Cancer: A Comprehensive Review	3
WITHDRAWN: Network Pharmacology and In vitro Experiments Reveal that Noscapine Induces Ros-mediated Apoptosis and Cell Cycle Arrest via PI3K/Akt/FoxO3a Signaling Pathway in Human Bladder Cancer Cells	3
Mechanism of Bispecific Antibodies and Clinical Research Advances in Lung Cancer	3
Dysregulated Epigenetics of Chordoma: Prognostic Markers and Therapeutic Targets	3
DTL is a Novel Downstream Gene of E2F1 that Promotes the Progression of Hepatocellular Carcinoma	3
Construction of an Oxidative Stress Risk Model to Analyze the Correlation Between Liver Cancer and Tumor Immunity	2
Advances in Ovarian Cancer Treatment Beyond PARP Inhibitors	2
The Clinicopathological and Prognostic Significance of the Expression of PD-L1 and MET Genes in Breast Cancer: Potential Therapeutic Targets	2
PIWIL1 Promotes Malignant Progression of Papillary Thyroid Carcinoma by Inducing EVA1A Expression	2
A Pan-cancer Analysis to Determine the Prognostic Analysis and Immune Infiltration of HSPA5	2
Saikosaponin B4 Suppression Cancer Progression by Inhibiting SW480 and SW620 Cells Proliferation via the PI3K/AKT/mTOR Pathway in Colon Cancer	2
WITHDRAWN: Comprehensive Analysis of the Role of CXCL Family Members in Clear Cell Renal Cell Carcinoma	2
EWS-RNA Binding Protein 1: Structural Insights into Ewing Sarcoma by Conformational Dynamics Investigations	2
Advances in Understanding How RhoB Regulates Akt Inhibition Efficacy in NSCLC	2
Exosomal circRNAs: The Key Role and Potential Therapeutic Target in Gastric Cancer	2
Mesenchymal Epithelial Transition (MET): A Key Player in Chemotherapy Resistance and an Emerging Target for Potentiating Cancer Immunotherapy	2
Advancement and Strategies for the Development of Peptide-drug Conjugates: Pharmacokinetic Modulation, Role and Clinical Evidence against Cancer Management	2
Functional Characterization and Prognostic Value of PIAS Family Genes in Liver Hepatocellular Carcinoma	2
Naringenin-induced Oral Cancer Cell Apoptosis Via ROS-mediated Bid and Bcl-xl Signaling Pathway	2
Recent Update on Nanoparticles Based Approaches for Management of Cancer: Wave from Traditional to Advanced Technology	2
Decoding Metastasis: From Cell Death to Fusion in Cancer Progression	2
Targeting Ferroptosis Pathways: A Novel Strategy for Cancer Therapy	2
Treatment Advances in Lung Cancer with Leptomeningeal Metastasis	2
CDK-associated Cullin 1 Promotes Cell Proliferation and Inhibits Cell Apoptosis in Human Glioblastoma	2
MALAT1 Promotes Tumorigenesis and Increases Cellular Sensitivity to Herceptin in HER2-positive Breast Cancer	2
Value of Label-Free Ubiquitin-Proteomic Analysis on Defining the Protective Mechanism of Valsartan against Doxorubicin-Induced Heart Failure	2
The Tumor Immune Microenvironment plays a Key Role in Driving the Progression of Cholangiocarcinoma	2
Impact of GSTT1 and GSTM1 Polymorphisms in the Susceptibility to Philadelphia Negative Chronic Myeloid Leukaemia	2
Exosomes Mediate the Production of Oxaliplatin Resistance and Affect Biological Behaviors of Colon Cancer Cell Lines	2
Preparation of Modified Chitosan-based Nanoparticles for Efficient Delivery of Doxorubicin and/or Cisplatin to Breast Cancer Cells	2
Cucurbitacin D Inhibits the Proliferation of HepG2 Cells and Induces Apoptosis by Modulating JAK/STAT3, PI3K/Akt/mTOR and MAPK Signaling Pathways	2
Future Management of Chronic Myeloid Leukemia: From Dose Optimization to New Agents	2
Overexpression of BRD4 in Gastric Cancer and its Clinical Significance as a Novel Therapeutic Target	2
Phosphoserine Aminotransferase 1: A Metabolic Enzyme Target of Cancers	2
An Overview of the Dichotomous Role of Microbiota in Cancer Progression and Management	2
MND1 Promotes the Proliferation of Prostate Cancer Cell Via the CCNB1/p53 Signaling Pathway	2
Novel Association of RAD54L Mutation with Müllerian Clear Cell Carcinoma of the Male Urethra: New Insights Regarding the Molecular Mechanisms of a Rare Tumour	2
Effect of HPV Oncoprotein on Carbohydrate and Lipid Metabolism in Tumor Cells	2
Novel Synergistic Combination of Pamidronate and Temozolomide for Breast Cancer Therapeutics	2
A Review of the Progress in the Diagnosis and Treatment of Pulmonary Sarcomatoid Carcinoma	2
EVI5 Drives Lung Adenocarcinoma Progression through Modulation of the ERK1/2-c-Myc Signaling Axis	2
Envafolimab Inhibits the Growth of Gastric Cancer Cells with Low PD-L1 Expression through the DDX20/NF-κB/TNF-α Signaling Pathway	2
SULF1 Activates the VEGFR2/PI3K/AKT Pathway to Promote the Development of Cervical Cancer	2
Inhibitor of Growth 4 (ING4) Plays a Tumor-repressing Role in Oral Squamous Cell Carcinoma via Nuclear Factor Kappa-B (NF-kB)/DNA Methyltransferase 1 (DNMT1) Axis-mediated Regulation of Aldehyde Dehyd	2
Geiparvarin Inhibits the Progression of Osteosarcoma by Down-regulating COX2 Expression	2
SPON2 Suppresses Autophagy by Regulating the PI3K/AKT/mTOR Signaling Pathway in Renal Cell Carcinoma	2
Zinc Finger Protein 536 is a Potential Prognostic Biomarker that Promotes Neuroblastoma Progression via VEGFR2-PI3K-AKT Pathway	2
Promotion of Melanoma Progression through MCM4-Induced Immune Suppression and Polarization of Macrophages by Carcinogenic Exosomes	2
Role of Immunotherapy in the Management of Advanced Hepatocellular Carcinoma: A Systematic Review	2
The Role of Lactate in Cancer Immunotherapy: Mechanisms and Applications	2
Arsenic Trioxide Restrains Lung Cancer Growth and Metastasis by Blocking the Calcineurin-NFAT Pathway by Upregulating DSCR1	2
Biology, Significance and Immune Signaling of Mucin 1 in Hepatocellular Carcinoma	2
Antibody-Drug Conjugates (ADCs): A Novel Therapy for Triple-Negative Breast Cancer (TNBC)	2
Low Expression MCEMP1 Promotes Lung Adenocarcinoma Progression and its Clinical Value	2
Increase in Cisplatin Resistance by MeCP2 in Human Gastric Cancer through the Activation of the AKT Pathway by Facilitating PDK-1 Transcription	2
Novel Compound, ND-17, Regulates the JAK/STAT, PI3K/AKT, and MAPK Pathways and Restrains Human T-lymphoid Leukemia Development	1
Anti-cancer Effects of 5-Aminoimidazole-4-Carboxamide-1-β-D-Ribofuranoside (AICAR) on Triple-negative Breast Cancer (TNBC) Cells: Mitochondrial Modulation as an Underlying Mechanism	1
Gamma-tocotrienol Inhibits Proliferation and Growth of HSD17B4 Overexpressing HepG2 Liver Cancer Cells	1
Targeting the Transforming Growth Factor-beta Signaling Pathway in the Treatment of Gynecologic Cancer	1
A Comprehensive Review on Anticancer Potential of Pulicaria Plants and their Derivatives	1
Groundbreaking mRNA Lung Cancer Vaccine Trials: A New Dawn in Cancer Treatment	1
Application of Thermoresponsive Smart Polymers based in situ Gel as a Novel Carrier for Tumor Targeting	1
Molecular Milieu of Autophagy in Cervical Cancer and its Therapeutic Implications	1
High Level of Adropin Promotes the Progression of Pancreatic Ductal Adenocarcinoma	1
Comprehensive Analysis of Diabetes Mellitus-related Gene Expression and Associated Prognoses in Human Lung Cancer	1
Role of NADPH Quinone Reductase 1 (NQO1) Polymorphism in Prevention, Diagnosis, and Treatment of Gastrointestinal Cancers	1
C-C Motif Chemokine Ligand 5 (CCL5): A Potential Biomarker and Immunotherapy Target for Osteosarcoma	1
Liquid-Liquid Phase Separation in the Prognosis of Lung Adenocarcinoma: An Integrated Analysis	1
A Comprehensive Evaluation of the Effectiveness and Safety of Pembrolizumab for the Treatment of Metastatic Colorectal Cancer: A Systematic Review and Meta-Analysis	1
Current Advances in Hepatocellular Carcinoma: Transition from Traditional to Advanced Technology	1
Molecular-targeted Therapy for Precision Medicine in Gastrointestinal Cancer: Advancement in Cancer Targeting Strategies	1
EZH2-regulated PARP-1 Expression is a Likely Mechanism for the Chemoresistance of Gliomas to Temozolomide	1
Exploring the Antitumor Efficacy of PEGylated Liposomes Loaded with Licorice Extract for Cancer Therapy	1
Vitamin D Affects the Warburg Effect and Stemness Maintenance of Non- Small-Cell Lung Cancer Cells by Regulating the PI3K/AKT/mTOR Signaling Pathway	1
Dextran Sulfate Inhibits Angiogenesis and Invasion of Gastric Cancer by Interfering with M2-type Macrophages Polarization	1
Cardiovascular Mortality Risk Among Patients with Liver Cancer: A SEER Database Study	1
Nucleolin as a Crucial Player in Head and Neck Cancer: Diagnostic andTherapeutic Perspectives	1
Tectorigenin Inhibits Glycolysis-induced Cell Growth and Proliferation by Modulating LncRNA CCAT2/miR-145 Pathway in Colorectal Cancer	1
Expression, Characteristics, and Clinical Target Prediction of PIK3C3/ vps34 in Gastric Cancer	1