Current Cancer Drug Targets

Article	Citations
Micro-fragmented Fat Inhibits the Progression of Human Mesothelioma Xenografts in Mice	89
Immune Checkpoint Inhibitors for Advanced Biliary Tract Cancer	44
Development of Chromatin Regulator-related Molecular Subtypes and a Signature to Predict Prognosis and Immunotherapeutic Response in Head and Neck Squamous Cell Carcinoma	38
Spinal KCC2 Mediates the Modulation Effect of HDAC2 on Bone Cancer Pain in Rats	36
A Review on Patient-derived 3D Micro Cancer Approach for Drug Screen in Personalized Cancer Medicine	30
Etiology-based Molecular Characterization of Hepatocellular Carcinoma Reveals SQLE's Contribution to Immunosuppressive Microenvironment	29
A Pilot Study of Anlotinib as a Combination Treatment in Advanced Nasopharyngeal Carcinoma	27
Progress in Metabolic Studies of Gastric Cancer and Therapeutic Implications	27
LMNB1/CDKN1A Signaling Regulates the Cell Cycle and Promotes Hepatocellular Carcinoma Progression	26
TBOPP, a DOCK1 Inhibitor, Potentiates Cisplatin Efficacy in Breast Cancer by Regulating Twist-mediated EMT	24
Expression, Prognostic Value, and Immune Infiltration of MTHFD Family in Bladder Cancer	23
Efficacy and Safety of Immunotherapy Combined with Anlotinib as First-Line Treatment in Older NSCLC Patients with PD-L1 Expression<50%	18
Bioinformatics and Experimental Study Revealed LINC00982/ miR-183-5p/ABCA8 Axis Suppresses LUAD Progression	18
Knockdown of PRKD2 Enhances Chemotherapy Sensitivity in Cervical Cancer via the TP53/CDKN1A Pathway	16
The Therapeutic Potential of Urolithin A for Cancer Treatment and Prevention	16
Silencing HEATR1 Rescues Cisplatin Resistance of Non-small Cell Lung Cancer by Inducing Ferroptosis via the p53/SAT1/ALOX15 Axis	15
Combined RNAi of CTTN and FGF2 Modulates Cell Migration, Invasion and G1/S Transition of Hepatocellular Carcinoma through Ras/ERK Signaling Pathway	15
The Expression of Glutaminases and their Association with Clinicopathological Parameters in the Head and Neck Cancers	15
FHOD3 Promotes the Progression of Lung Cancer by Regulating the Caspase-3-Mediated Signaling Pathway	15
EGF/EGFR Promotes Salivary Adenoid Cystic Carcinoma Cell Malignant Neural Invasion via Activation of PI3K/AKT and MEK/ERK Signaling	14
Role of Natural Nuclear Factor Erythroid-2-related Factor 2 (Nrf2) Activators in Oral and Head and Neck Cancer Treatment	14
LINC00461 Knockdown Enhances the Effect of Ixazomib in Multiple Myeloma Cells	14
Identification of ATM Mutation as a Potential Prognostic Biomarker for Immune Checkpoint Inhibitors Therapy	14
Low Expression of SCN4B Predicts Poor Prognosis in Non-small Cell Lung Cancer	14
High Expression of PKMYT1 Predicts Poor Prognosis and Aggravates the Progression of Osteosarcoma via the NF-κB Pathway in MG63 Cells	14

WITHDRAWN: Use of Tumor-Infiltrating Lymphocyte (TIL) Cell Therapy for Spindle Cell Carcinoma of the Breast: A Case Report	13
MMP7, Regulated by c-Jun, is Involved in Oral Squamous Cell Carcinoma and Associated with Cancer-Related Fibroblasts Infiltration	13
Downregulation of CCKBR Expression Inhibits the Proliferation of Gastric Cancer Cells, Revealing a Potential Target for Immunotoxin Therapy	13
PLCG2, A Regulator of Lung Adenocarcinoma Proliferation and Migration Associated with Immune Infiltration	13
Epigallocatechin-3-gallate Induced HepG2 Cells Apoptosis through ROSmediated AKT /JNK and p53 Signaling Pathway	13
Nanodiamond Mediated Molecular Targeting in Pancreatic Ductal Adenocarcinoma: Disrupting the Tumor-stromal Cross-talk, Next Hope on the Horizon?	12
Inorganic Phosphate (Pi) in the Breast Cancer Microenvironment: Production, Transport and Signal Transduction as Potential Targets for Anticancer Strategies	12
Review Deciphering the Potential of Nanotherapeutics in Lung Cancer Management	12
Identification of AHSA1 as a Potential Therapeutic Target for Breast Cancer: Bioinformatics Analysis and in vitro Studies	11
An Updated Review on Molecular Biomarkers in Diagnosis and Therapy of Colorectal Cancer	11
Angiotensin-converting Enzyme Inhibitors and Angiotensin Receptor Blockers as Potential Therapeutic Options for Pancreatic Cancer	10
Utilization of DNA Replication factor MCM2 by Cancer	10
Protein Tyrosine Phosphatase 1B (PTP1B): Insights into its New Implications in Tumorigenesis	10
Preventive and Therapeutic effects of Metformin in Cancer: A Meta-Analysis of RCT and Cohort Studies	10
Comprehensive Pan-cancer Analysis of CMPK2 as Biomarker and Prognostic Indicator for Immunotherapy	10
Elucidating the Potential of E-cadherin Re-expression along with Trichostatin A and Zebularine in Enhancing Tumour Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)-Induced Apoptosis in Human	10
WITHDRAWN: Hidrosmin Attenuates Inflammatory Response Induced by IL1β by Suppressing the Activation of NF-κB Involving Nrf2/HO1Pathway in Human Osteoarthritis Chondrocytes	10
Solid CaCO3 Formation in Glioblastoma Multiforme and its Treatment with Ultra-Nanoparticulated NPt-Bionanocatalysts	10
CEA-regulated Oncolytic Virus Anticancer Therapy: A Promising Strategy for Rare Solid Tumors	9
Transcription Factor MAZ Potentiates the Upregulated NEIL3-mediated Aerobic Glycolysis, thereby Promoting Angiogenesis in Hepatocellular Carcinoma	9
Stabilizing Scaffold for Short Peptides Based on Knottins	9
A Saffron-based Polyherbal Formulation DuK Prevents Hepatocellular Carcinoma in Male Wistar Rats	9
Real-world Study on the Effect of PARPi as Maintenance Therapy on Platinum Sensitivity after First- and Second-line Chemotherapy in Patients with Recurrent High-grade Serous Epithelial Ovarian Cancer	9
Twenty-four-month Progression-free Survival in HER2-amplified Advanced Gastric Cancer with Brain Metastases after Trastuzumab Deruxtecan Treatment: A Case Report and Literature Review	9
Curcumin Inhibits Vasculogenic Mimicry via Regulating ETS-1 in Renal Cell Carcinoma	9
Withaferin A Inhibits Liver Cancer Tumorigenesis by Suppressing Aerobic Glycolysis through the p53/IDH1/HIF-1α Signaling Axis	9
Anti-breast Cancer Potential of Prosopis cineraria L. Phytocompounds: A Network Pharmacology and in vitro Analysisbased Approach	9
Screening miRNAs to Hinder the Tumorigenesis of Renal Clear Cell Carcinoma Associated with KDR Expression	9
Gender Matters. Sex-related Differences in Immunotherapy Outcome in Patients with Non-small Cell Lung Cancer	8
FA-HA-Amygdalin@Fe2O3 and/or γ-Rays Affecting SIRT1 Regulation of YAP/TAZ-p53 Signaling and Modulates Tumorigenicity of MDA-MB231 or MCF-7 Cancer Cells	8
RON Receptor Tyrosine Kinase in Tumorigenic Stemness as a Therapeutic Target of Antibody-drug Conjugates for Eradication of Triple-negative Breast Cancer Stem Cells	8
HIF-1α/Malat1/miR-141 Axis Activates Autophagy to Increase Proliferation, Migration, and Invasion in Triple-negative Breast Cancer	8
Promotion of Cervical Cancer Cell Proliferation by miR-130b Expression Level Changes and Inhibition of its Apoptosis by Targeting CDKN1A Gene	8
Precision Medicine in Colorectal Cancer: Targeted Therapies and Biomarker Insights	8
Long Non-Coding RNA HCP5 Affects Ferroptosis in Lung Adenocarcinoma through miR-17-5p/HOXA7 Axis	8
CDK8 as a therapeutic target for overall survival prediction in cervical squamous cell carcinoma (CESC)	8
Autophagy in Cancer Cell Transformation: A Potential Novel Therapeutic Strategy	8
Neuronatin Promotes the Progression of Non-small Cell Lung Cancer by Activating the NF-κB Signaling	8
Recent Advancements in Drug Targeting for Ferroptosis as an Antitumor Therapy: Development of Novel therapeutics	8
Targeting Glutamine Metabolic Reprogramming in Pancreatic Cancer: Current Insights and Future Directions	8
Progressive Dynamics of Cancer Stem Cells in Oral Squamous Cell Carcinoma	8
Cancer Vaccine in Cold Tumors: Clinical Landscape, Challenges, and Opportunities	8
Exploring the Role of Long Non-Coding RNAs in Mediating Cisplatin Resistance in Colorectal Cancer	7
WEE Family Kinase Inhibitors Combined with Sorafenib Can Selectively Inhibit HCC Cell Proliferation	7
Efficacy and Safety of Phosphatidylinositol 3-kinase Inhibitors for Patients with Breast Cancer: A Systematic Review and Meta-analysis of Randomized Controlled Trials	7
TROP2 Down-regulated DSG2 to Promote Gastric Cancer Cell Invasion and Migration by EGFR/AKT and DSG2/PG/β-Catenin Pathways	7
Exploring the Impact of Chitosan-Based Nanoparticles in Cancer Targeted Drug Delivery: A Bibliometric Review	7
Exosome-mediated Induction of Apoptosis in Cisplatin-treated GastricCancer Cells as a Strategy to Mitigate Side Effects	7
Pathological Implications of Mucin Signaling in Metastasis	7
Advances and Future Prospects of Lipid-Based Nanocarriers in Targeted Cancer Therapy: A Comprehensive Review	7

Combinatorial Application of Papain and CD66B for Isolating Glioma- Associated Neutrophils	7
The Imidazacridine Derivative LPSF/AC-05 Induces Apoptosis, Cell Cycle Arrest, and Topoisomerase II Inhibition in Breast Cancer, Leukemia, and Lymphoma	7
Is the Use of SGLT-2 Associated with an Increased Risk of Cancer?	7
Silencing TRIM29 Sensitizes Non-small Cell Lung Cancer Cells to Anlotinib by Promoting Apoptosis via Binding RAD50	7
Elucidation of the Role of the Epigenetic Regulatory Mechanisms of PI3K/Akt/mTOR Signaling Pathway in Human Malignancies	7
Chimeric Antigen Receptor (CAR) T-cell Therapy: A New Genetically Engineered Method of Immunotherapy for Cancer	7
Integrative Deep Learning from H&E Images Reveals Prognostically Distinct Pathology-Based Subtypes in Bladder Cancer	6
L-lysine Increases the Anticancer Effect of Doxorubicin in Breast Cancer by Inducing ROS-dependent Autophagy	6
RAD50 Deficient in a Breast Cancer Model Predicts Sensitivity to PARP Inhibitors	6
YM155 Restores the Effect of Imatinib in Imatinib-Resistant Chronic Myeloid Leukemia Cell Lines	6
A Novel Platinum-Resistance-related Gene Signature in Ovarian Cancer: Identification and Patient-derived Organoids Verification	6
COL10A1 as a Prognostic Biomarker in Association with Immune Infiltration in Prostate Cancer	6
Comparison of Surgical and Colonoscopy Tissue to Establish Colorectal Patient-derived Organoids	6
Silencing of FANCI Promotes DNA Damage and Sensitizes Ovarian Cancer Cells to Carboplatin	6
Controversial Role of Opioids: From Pain Control to Cancer Recurrence in Breast Cancer	6
UCA1 Inhibits NKG2D-mediated Cytotoxicity of NK Cells to Breast Cancer	6
Coriandrum sativum and Aloysia triphylla can Protect the Development of Cancer: An in Vivo Study using Mouse Painting Assay	6
mirna-383-5p Functions as an Anti-oncogene in Glioma through the Akt/mTOR Signaling Pathway by Targeting VEGFA	6
Repurposing of Antidiarrheal Loperamide for Treating Melanoma by Inducing Cell Apoptosis and Cell Metastasis Suppression In vitro and In vivo	6
Tumor-Activated Neutrophils Promote Lung Cancer Progression through the IL-8/PD-L1 Pathway	6
Cuproptosis Related Gene DLD Associated with Poor Prognosis and Malignant Biological Characteristics in Lung Adenocarcinoma	6
Angiogenesis and Pancreatic Cancer: Novel Approaches to Overcome Treatment Resistance	6
A Novel Oncogenic Role of Disulfidptosis-related Gene SLC7A11 in Anti-tumor Immunotherapy Response to Human Cancers	6
Assessing Long Non-coding RNAs in Tobacco-associated Oral Cancer	6
Combination Therapy with Androgen Receptor Pathway Inhibitors for Prostate Cancer	6
Unveiling the Therapeutic Potential of Compounds Carrying Mono- and Bis-Thiazole Nuclei with Distinct Heterocyclic Analogues for Addressing Cancer Challenges	6
Targeting the Tumor Epigenetic Regulator SETDB1 for Tumor Therapy	5
Research Advances of Clinical Application of Oncolytic Viruses in Treatment of Gynecologic Cancers	5
Advances in Radiation Therapy Enhancement and Radio-Protection By Nano-Curcumins: A Systematic Review	5
ZIP14 Affects the Proliferation, Apoptosis, and Migration of Cervical Cancer Cells by Regulating the P38 MAPK Pathway	5
Unravelling the Mechanism of Methylophiopogonanone A Against Esophageal Squamous Cell Carcinoma Based on Network Pharmacology and Molecular Docking	5
Antibody-drug Conjugate Targets, Drugs, and Linkers	5
Forkhead Box Protein M1 (FOXM1): Prospective Prognostic Biomarker and Therapeutic Targets in Oral Cancer	5
ADH1B Gene Promotes Gastric Cancer Tumorigenesis and its Cisplatin Resistance through the EMT Pathway	5
The Effects of Mesenchymal Stem Cells Loaded with Oncolytic Coxsackievirus A21 on Mouse Models of Colorectal Cancer	5
Nanotechnological Advancements for the Theranostic Intervention in Anaplastic Thyroid Cancer: Current Perspectives and Future Direction	5
Dietary Flavonoids with Catechol Moiety Inhibit Anticancer Action of Bortezomib: What about the other Boronic Acid-based Drugs?	5
The Influence of KIR Gene Polymorphisms and KIR-ligand Binding on Outcomes in Hematologic Malignancies following Haploidentical Stem Cell Transplantation: A Comprehensive Review	5
Preface	5
VX-765 has a Protective Effect on Mice with Ovarian Injury Caused by Chemotherapy	5
Molecular Targets and Nano-Technological Approaches in the Treatment of Hepatic Carcinoma	5
The Clinical Role of Hypoxia Inducible Factor (HIF) Inhibition in Renal Cancer: A Focus on Belzutifan	5
Resistance of Lenvatinib in Hepatocellular Carcinoma	5
Research Progress of Neural Invasion in Pancreatic Cancer	5
Polyphyllin VII is a Potential Drug Targeting CD44 Positive Colon Cancer Cells	5
Efficacy and Safety of Nimotuzumab in Combination with Radiotherapy or Chemoradiotherapy for Local Advanced Head and Neck Cancer: A Systematic Review and Meta-analysis	5
IR-780 Dye-based Targeting of Cancer-associated Fibroblasts Improves Cancer Immunotherapy by Increasing Intra-tumoral T Lymphocytes Infiltration	5
Up-regulation of Core 1 Beta 1, 3-Galactosyltransferase Suppresses Osteosarcoma Growth with Induction of IFN-γ Secretion and Proliferation of CD8+ T Cells	4
The Role of Local Angiotensin II/Angiotensin Type 1-receptor Mechanisms in Adipose Tissue Dysfunction to Promote Pancreatic Cancer	4
Combined Immunotherapy and Targeted Therapies for Cancer Treatment: Recent Advances and Future Perspectives	4
Recent Progress in the Application of Exosome Analysis in Ovarian Cancer Management	4
The Association between NADPH Oxidase 2 (NOX2) and Drug Resistance in Cancer	4
Effects of HSV-G47Δ Oncolytic Virus on Telomerase and Telomere Length Alterations in Glioblastoma Multiforme Cancer Stem Cells Under Hypoxia and Normoxia Conditions	4
Comprehensive Pan-cancer Analysis and Experimental Verification of EGLN Family: Potential Biomarkers in Cervical Cancer	4
GAPVD1 Promotes the Proliferation of Triple-negative Breast Cancer Cells by Regulating the ERK/MAPK Signaling Pathway	4
GPX4 Inhibition Enhances the Antitumor Effect of PARP Inhibitor on Homologous Recombination Proficient Ovarian Cancer Cells	4
Durable Disease-free Survival in a Patient with Metastatic Triple-negative Breast Cancer Treated with Olaparib Monotherapy	4
Preface	4
AHNAK2 Promotes the Progression of Differentiated Thyroid Cancer through PI3K/AKT Signaling Pathway	4
Sildenafil Inhibits the Growth and Epithelial-to-mesenchymal Transition of Cervical Cancer via the TGF-β1/Smad2/3 Pathway	4
Smart Nanobiomaterials for Gene Delivery in Localized Cancer Therapy: An Overview from Emerging Materials and Devices to Clinical Applications	4
Comprehensive Immune Subtyping and Multi-Omics Profiling of the Tumor Microenvironment in Colorectal Cancer: Implications for Prognosis and Personalized Immunotherapy	4
Traditional Chinese Medicine Targeting Sarcoma Virus Oncogene-related Diseases	4
Εmerging Biomarkers in the Diagnosis and Treatment of Testicular Tumors	4
Present and Future Prospects of the Anti-cancer Activities of Saikosaponins	4
Insights into the Emerging Therapeutic Targets of Triple-negative Breast Cancer	4
Mitochondrial Calcium Uniporter (MCU) that Modulates Mitochondrial Calcium Uptake and Facilitates Endometrial Cancer Progression through Interaction with VDAC1	4
Disulfiram-Copper Potentiates Anticancer Efficacy of Standard Chemotherapy Drugs in Bladder Cancer Animal Model through ROS-Autophagy-Ferroptosis Signalling Cascade	4
Dihydrotanshinone I Inhibits Pancreatic Cancer Progression via Hedgehog/ Gli Signal Pathway	4
Perspectives on Ergodic Cancer Therapy Derived from Cloning Genome Chaos via In Vivo Rhabdomyosarcoma RA-2 Models: a Narrative Review	4
Study on Cellular Localization of Bin Toxin and its Apoptosis-inducing Effect on Human Nasopharyngeal Carcinoma Cells	4
Modifications of Ribonucleases in Order to Enhance Cytotoxicity in Anticancer Therapy	4
The Prognostic Value and Clinical Significance of lncRNA SNHG5 Expression in Patients with Multiple Malignancies: A Bioinformatic and Meta-analysis	4
Role of Non-Coding RNAs in Regulating PD-L1 Expression in Breast Cancer: Emerging Insights and Implications	3
IL-33/ST2 Signaling and its Correlation with Macrophage Heterogeneity and Clinicopathologic Features in Human Intrahepatic Cholangiocarcinoma	3
H3K27ac-activated LncRNA NUTM2A-AS1 Facilitated the Progression of Colorectal Cancer Cells via MicroRNA-126-5p/FAM3C Axis	3
Embracing the Circular Journey of RNA in Colorectal Cancer	3
Raddeanoside R13 Inhibits Proliferation, Invasion, and Metastasis of Gastric Cancer Cells Based on Network Pharmacology and Experimental Validation	3
Comprehensive Analysis Identifies Tumor Mutation Burden-associated Genes ASPM and KIF11 as Novel Biomarkers for Adrenocortical Carcinoma	3
CT109-SN-38, a Novel Antibody-drug Conjugate with Dual Specificity for CEACAM5 and 6, Elicits Potent Killing of Pancreatic Cancer Cells	3

CircRNAs Regulate Senescence-Associated miRNAs in Gastric Cancer	3
Geiparvarin Inhibits the Progression of Osteosarcoma by Down-regulating COX2 Expression	3
Exosomes Mediate the Production of Oxaliplatin Resistance and Affect Biological Behaviors of Colon Cancer Cell Lines	3
WITHDRAWN: Comprehensive Analysis of the Role of CXCL Family Members in Clear Cell Renal Cell Carcinoma	3
GOLM1-induced Vascular Permeability and Angiogenesis in Hepatocellular Carcinoma through Modulation of Cancer Cell-derived Exosomal microRNAs	3
Mechanism of Bispecific Antibodies and Clinical Research Advances in Lung Cancer	3
Prospective Clinical and Biochemical Evaluation of Breast Cancer in Patient Cohorts	3
WITHDRAWN: Network Pharmacology and In vitro Experiments Reveal that Noscapine Induces Ros-mediated Apoptosis and Cell Cycle Arrest via PI3K/Akt/FoxO3a Signaling Pathway in Human Bladder Cancer Cells	3
Netupitant-palonosetron (NEPA) for Preventing Chemotherapy-induced Nausea and Vomiting: From Clinical Trials to Daily Practice	3
Advancements in Phytosomal Therapies for Liver Cancer: A Comprehensive Review	3
Current Perspectives in Ultra-sensitive Detection of Cancer-specific Biomarkers and Therapeutic Targets	3
DTL is a Novel Downstream Gene of E2F1 that Promotes the Progression of Hepatocellular Carcinoma	3
Dysregulated Epigenetics of Chordoma: Prognostic Markers and Therapeutic Targets	3
Emerging Prospects for the Study of Colorectal Cancer Stem Cells using Patient-derived Organoids	3
Grafting of Resveratrol-Chitosan Nanoparticles as a Promising Radiosensitizer and Protector in DMBA-Induced Breast Cancer in Mice	3
Deubiquitylase USP31 Induces Autophagy and Promotes the Progression in Lung Squamous Cell Carcinoma Cells by Stabilizing E2F1 Expression	3
Gastroenteropancreatic Neuroendocrine Neoplasms (GEP NENs): The Role of Checkpoint Inhibitors	3
Experimental Determination of Cancer Drug Targets with Independent Mechanisms of Resistance	3
LINC00887 Acts as an Enhancer RNA to Promote Medullary Thyroid Carcinoma Progression by Binding with FOXQ1	3
The Role of Oxidative Stress in the Development and Therapeutic Intervention of Hepatocellular Carcinoma	3
RC48 Induces Senescence in HER2-Expressing Colon Cancer Cells by Activating the CDKN1A-RB-E2F1 Pathway	3
Clinical Efficacy and Safety of Anlotinib Combined with Immune Checkpoint Inhibitors in the Treatment of Advanced Squamous Cell Lung Cancer: A Retrospective Single-Center Study in China	3
Corrigendum to: Low Expression MCEMP1 Promotes Lung Adenocarcinoma Progression and its Clinical Value	3
The Potential of Natural Products in the Treatment of Triple-negative Breast Cancer	3
Probiotics as a Therapeutic Approach in Colorectal Cancer	3
Targeting Ferroptosis Pathways: A Novel Strategy for Cancer Therapy	2
The Tumor Immune Microenvironment plays a Key Role in Driving the Progression of Cholangiocarcinoma	2
The Clinicopathological and Prognostic Significance of the Expression of PD-L1 and MET Genes in Breast Cancer: Potential Therapeutic Targets	2
Increase in Cisplatin Resistance by MeCP2 in Human Gastric Cancer through the Activation of the AKT Pathway by Facilitating PDK-1 Transcription	2
EVI5 Drives Lung Adenocarcinoma Progression through Modulation of the ERK1/2-c-Myc Signaling Axis	2
Naringenin-induced Oral Cancer Cell Apoptosis Via ROS-mediated Bid and Bcl-xl Signaling Pathway	2
Saikosaponin B4 Suppression Cancer Progression by Inhibiting SW480 and SW620 Cells Proliferation via the PI3K/AKT/mTOR Pathway in Colon Cancer	2
Low Expression of GRIM-19 Correlates with Poor Prognosis in Patients with Upper Urinary Tract Urothelial Carcinoma	2
Computational Design for Identification of Human Anti-MUC1 Heteroclitic Peptides in the Treatment of HER2-Positive Breast Cancer through Neural Network Training and Monomeric based Design	2
Fe3O4-viral-like Mesoporous Silica Nanoparticle(Fe3O4-vMSN)-Sustained Release of Lenvatinib for Targeted Treatment of Hepatocellular Carcinoma	2
Zinc Finger Protein 536 is a Potential Prognostic Biomarker that Promotes Neuroblastoma Progression via VEGFR2-PI3K-AKT Pathway	2
Novel Synergistic Combination of Pamidronate and Temozolomide for Breast Cancer Therapeutics	2
MND1 Promotes the Proliferation of Prostate Cancer Cell Via the CCNB1/p53 Signaling Pathway	2
Advances in Ovarian Cancer Treatment Beyond PARP Inhibitors	2
Exosomal circRNAs: The Key Role and Potential Therapeutic Target in Gastric Cancer	2
Phosphoserine Aminotransferase 1: A Metabolic Enzyme Target of Cancers	2
Advances in Nanomaterials for Targeted Drug Delivery: Emerging Trends and Future Prospects in Nanodrug Development	2
Novel Association of RAD54L Mutation with Müllerian Clear Cell Carcinoma of the Male Urethra: New Insights Regarding the Molecular Mechanisms of a Rare Tumour	2
Extraordinary Benefit of Regorafenib in Metastatic Cholangiocarcinoma: A Case Report	2
The Role of Lactate in Cancer Immunotherapy: Mechanisms and Applications	2
Identification of Necroptosis-related Subtypes and Characterization of Tumor Microenvironment Infiltration in Non-small Cell Lung Cancer	2
Construction of an Oxidative Stress Risk Model to Analyze the Correlation Between Liver Cancer and Tumor Immunity	2
Treatment Advances in Lung Cancer with Leptomeningeal Metastasis	2
Functional Characterization and Prognostic Value of PIAS Family Genes in Liver Hepatocellular Carcinoma	2
Mesenchymal Epithelial Transition (MET): A Key Player in Chemotherapy Resistance and an Emerging Target for Potentiating Cancer Immunotherapy	2
A Pan-cancer Analysis to Determine the Prognostic Analysis and Immune Infiltration of HSPA5	2
Future Management of Chronic Myeloid Leukemia: From Dose Optimization to New Agents	2
Biology, Significance and Immune Signaling of Mucin 1 in Hepatocellular Carcinoma	2
The HGF/Met Receptor Mediates Cytotoxic Effect of Bacterial Cyclodipeptides in Human Cervical Cancer Cells	2
Arsenic Trioxide Restrains Lung Cancer Growth and Metastasis by Blocking the Calcineurin-NFAT Pathway by Upregulating DSCR1	2
Advancement and Strategies for the Development of Peptide-drug Conjugates: Pharmacokinetic Modulation, Role and Clinical Evidence against Cancer Management	2
Establishment and Validation of a Blood Test-based Nomogram to Diagnose Patients with AFP-negative HCC	2
SPON2 Suppresses Autophagy by Regulating the PI3K/AKT/mTOR Signaling Pathway in Renal Cell Carcinoma	2
A Review of the Progress in the Diagnosis and Treatment of Pulmonary Sarcomatoid Carcinoma	2
HAND2-AS1 Promotes Ferroptosis to Reverse Lenvatinib Resistance in Hepatocellular Carcinoma by TLR4/NOX2/DUOX2 Axis	2
Cucurbitacin D Inhibits the Proliferation of HepG2 Cells and Induces Apoptosis by Modulating JAK/STAT3, PI3K/Akt/mTOR and MAPK Signaling Pathways	2
Therapeutic Potential of Clostridium novyi-NT in Cancer: Current Knowledge and Future Perspectives	2
Low Expression MCEMP1 Promotes Lung Adenocarcinoma Progression and its Clinical Value	2
Combined Inhibition of KIF11 and KIF15 as an Effective Therapeutic Strategy for Gastric Cancer	2
EWS-RNA Binding Protein 1: Structural Insights into Ewing Sarcoma by Conformational Dynamics Investigations	2
Role of Immunotherapy in the Management of Advanced Hepatocellular Carcinoma: A Systematic Review	2
SULF1 Activates the VEGFR2/PI3K/AKT Pathway to Promote the Development of Cervical Cancer	2
Effect of HPV Oncoprotein on Carbohydrate and Lipid Metabolism in Tumor Cells	2
Value of Label-Free Ubiquitin-Proteomic Analysis on Defining the Protective Mechanism of Valsartan against Doxorubicin-Induced Heart Failure	2
Antibody-Drug Conjugates (ADCs): A Novel Therapy for Triple-Negative Breast Cancer (TNBC)	2
Overexpression of BRD4 in Gastric Cancer and its Clinical Significance as a Novel Therapeutic Target	2
Inhibitor of Growth 4 (ING4) Plays a Tumor-repressing Role in Oral Squamous Cell Carcinoma via Nuclear Factor Kappa-B (NF-kB)/DNA Methyltransferase 1 (DNMT1) Axis-mediated Regulation of Aldehyde Dehyd	2
Impact of GSTT1 and GSTM1 Polymorphisms in the Susceptibility to Philadelphia Negative Chronic Myeloid Leukaemia	2
Promotion of Melanoma Progression through MCM4-Induced Immune Suppression and Polarization of Macrophages by Carcinogenic Exosomes	2
Decoding Metastasis: From Cell Death to Fusion in Cancer Progression	2
Combined Transarterial Chemoembolization with Microwave Ablation versus Microwave Alone for Treatment of Medium Sized Hepatocellular Carcinoma	2
Recent Update on Nanoparticles Based Approaches for Management of Cancer: Wave from Traditional to Advanced Technology	2
GRP78 is Overexpressed in Non-small Cell Lung Cancer Tissues and is Associated with High VEGF Expression in Squamous Cell Carcinoma: A Pilot Study	2
Preparation of Modified Chitosan-based Nanoparticles for Efficient Delivery of Doxorubicin and/or Cisplatin to Breast Cancer Cells	2
Envafolimab Inhibits the Growth of Gastric Cancer Cells with Low PD-L1 Expression through the DDX20/NF-κB/TNF-α Signaling Pathway	2
Variants in CYP2J2 and CYP2C9 Contribute to Susceptibility of Lung Cancer	2
PIWIL1 Promotes Malignant Progression of Papillary Thyroid Carcinoma by Inducing EVA1A Expression	2
Early Detection, Precision Treatment, Recurrence Monitoring: Liquid Biopsy Transforms Colorectal Cancer Therapy	2
Advances in Understanding How RhoB Regulates Akt Inhibition Efficacy in NSCLC	2
BZW2, CDT1 and IVD Act As Biomarkers for Predicting Hepatocellular Carcinoma	2
An Overview of the Dichotomous Role of Microbiota in Cancer Progression and Management	2
Elucidating the Role of Pro-renin Receptors in Pancreatic Ductal Adenocarcinoma Progression: A Novel Therapeutic Target in Cancer Therapy	2