OOIR: Observatory of International Research

Papers

(The TQCC of Mitochondrion is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Sequencing errors in Native American mitogenomes: Impact on clade definitions, haplogroup assignation, and beyond	210
The tissue-specific nature of physiological zebrafish mitochondrial bioenergetics	101
The multifaceted modulation of mitochondrial metabolism in tumorigenesis	67
CMT2A-linked MFN2 mutation, T206I promotes mitochondrial hyperfusion and predisposes cells towards mitophagy	65
A Tunisian POLG mutation expands the clinical spectrum of POLG-related disorders	62
Editorial Board	59
Delivery of mitoceuticals or respiratory competent mitochondria to sites of neurotrauma	57
Activation of multifunctional DNA repair APE1/Ref-1 enzyme by the dietary phytochemical Ferulic acid protects human neuroblastoma SH-SY5Y cells against Aβ(25–35)-induced oxidative stress and inflammat	54
ACAD9 treatment with bezafibrate and nicotinamide riboside temporarily stabilizes cardiomyopathy and lactic acidosis	45
What can we do to optimize mitochondrial transplantation therapy for myocardial ischemia–reperfusion injury?	43
The role of mitochondrial genes in ischemia-reperfusion injury: A systematic review of experimental studies	41
Mitochondrial density in skeletal and cardiac muscle	40
Editorial Board	38
PhNR and peripapillary RNFL changes in Leber hereditary optic neuropathy with m.G11778A mutation	38
Editorial Board	38
Thyroid hormone enhances efficacy of cisplatin in lung cancer patients via down-regulating GLUT1 expression and reversing the Warburg effect	35
Paternal aging impacts mitochondrial DNA content and telomere length in mouse embryos	34
The war against Alzheimer, the mitochondrion strikes back!	34
Reanalysis of mtDNA mutations of human primordial germ cells (PGCs) reveals NUMT contamination and suggests that selection in PGCs may be positive	33
Mitochondria in biology and medicine – 2023	30
PKM2 is a key regulator of cardiac lipid metabolism in mice	30
Mrs2-mediated mitochondrial magnesium uptake is essential for the regulation of MCU-mediated mitochondrial Ca2+ uptake and viability	29
The evolving landscape of mitochondrial base editing: advances in precision, modeling, and therapeutic potential	28
Reactive oxygen species favors Varicellovirus bovinealpha 5 (BoAHV-5) replication in neural cells	28
Site-specific mitochondrial dysfunction in neurodegeneration	28

Pyridoxal-5-phosphate mitigates age-related metabolic imbalances in the rat heart through the H2S/AKT/GSK3β signaling axis	26
Genomic and non-genomic action of vitamin D on ion channels – Targeting mitochondria	26
Muscle-UCP3 in the regulation of energy metabolism	25
Mitochondrial genome-derived circRNAs: Orphan epigenetic regulators in molecular biology	25
Exploring the role of mitochondria transfer/transplant and their long-non-coding RNAs in regenerative therapies for skin aging	24
TRPV4 acts as a mitochondrial Ca2+-importer and regulates mitochondrial temperature and metabolism	24
Mitochondrial Irc3 helicase of the thermotolerant yeast Ogataea polymorpha displays dual DNA- and RNA-stimulated ATPase activity	24
Intravenous mitochondrial transplantation as an adjunctive therapy for dilated cardiomyopathy	24
COXFA4L3 enhances mitochondrial complex IV function to boost ATP synthesis and drive sperm motility	23
Reviewing the mitochondrial dysfunction paradigm in rodent models as platforms for neuropsychiatric disease research	23
Decoding the nature and complexity of extracellular mtDNA: Types and implications for health and disease	22
COVID-19 induced liver injury from a new perspective: Mitochondria	22
Mitochondrial transplantation therapy inhibits the proliferation of malignant hepatocellular carcinoma and its mechanism	22
The maternal genetic history of tribal populations of Chhattisgarh, India	21
Impact of missense mutations on the structure–function relationship of human succinyl-CoA synthetase using in silico analysis	21
Newer mitochondrial dynamics and their role of calcium signalling in liver regeneration	21
Editorial Board	20
Advancing mitochondria as a therapeutic agent	20
Association analysis of mitochondrial DNA heteroplasmic variants: Methods and application	20
Unmasking NLRX1: Exploring the broadening biological landscape of a mysterious mitochondrial sensor	20
2-Aminoethoxydiphenyl borate ameliorates mitochondrial dysfunctions in MPTP/MPP+ model of Parkinson’s disease	19
Mitochondria dysfunction and impaired response to oxidative stress promotes proteostasis disruption in aged human cells	19
Urolithin-A supplementation alleviates sepsis-induced acute lung injury by reducing mitochondrial dysfunction and modulating macrophage polarization	19
Understanding differential aspects of microdiffusion (channeling) in the Coenzyme Q and Cytochrome c regions of the mitochondrial respiratory system	19
Serum TCA cycle metabolites in Lewy bodies dementia and Alzheimer's disease: Network analysis and cognitive prognosis	18
Targeted mitochondrial metabolism for anti-tumor therapy	18
Mitochondrial oxidative stress in brain microvascular endothelial cells: Triggering blood-brain barrier disruption	18
Kinetic characterization of respirasomes and free complex I from Yarrowia lipolytica	18
Interplay of mitochondria and diabetes: Unveiling novel therapeutic strategies	18
Mitochondrial Transcription: A click-chemistry derived detection methodology forgoing the use of radiation in in vitro analyses	17
An integrated multi-omics approach allowed ultra-rapid diagnosis of a deep intronic pathogenic variant in PDHX and precision treatment in a neonate critically ill with lactic acidosis	17
Mitochondrial quality control in exercise-mitigated muscular atrophy	17
Mitochondrial dysfunction and inflammasome activation in neurodegenerative diseases: Mechanisms and therapeutic implications	17
The biology of mitochondrial carrier homolog 2	17
Application research of novel peptide mitochondrial-targeted antioxidant SS-31 in mitigating mitochondrial dysfunction	17
Whole genome sequencing followed by functional analysis of genomic deletion encompassing ERCC8 and NDUFAF2 genes in a non-consanguineous Indian family reveals dysfunctional mitochondrial bioenergetics	16
Novel mutations in MTERF3: First report of a new genetic cause in two Chinese patients with developmental delay, intermittent hypoglycemia and metabolic acidosis	16
Mitochondrial dysfunction–induced PANoptosis: Mechanisms, triggers, and disease implications	15
Prognostic value of circulating mitochondrial DNA in prostate cancer and underlying mechanism	15
Mitochondrial bioenergetics of breast cancer	15
Targeting the mitochondria in chronic respiratory diseases	15
Neuroprotective compounds alter the expression of genes coding for proteins related to mitochondrial function in activated microglia	15
Research progress on paternal mitochondrial inheritance: An overview	14
Targeting mitochondria with small molecules: A promising strategy for combating Parkinson’s disease	14
Miro1 improves the exogenous engraftment efficiency and therapeutic potential of mitochondria transfer using Wharton's jelly mesenchymal stem cells	14
Selective and reversible disruption of mitochondrial inner membrane protein complexes by lipophilic cations	14
The Parkinson’s disease-associated mutation LRRK2 G2385R alters mitochondrial biogenesis via the PGC-1α-TFAM pathway	14
RTN3 deficiency exacerbates cisplatin-induced acute kidney injury through the disruption of mitochondrial stability	14
Defining ER-mitochondria contact dynamics in Plasmodium falciparum by targeting component of phospholipid synthesis pathway, phosphatidylserine synthase (PfPSS)	14
Longitudinal changes in mitochondrial-associated measures and insulin resistance in youth with perinatally-acquired HIV in the U.S	13

Cancer/Testis Antigen 55 is required for cancer cell proliferation and mitochondrial DNA maintenance	13
Severe acute respiratory syndrome coronaviruses contributing to mitochondrial dysfunction: Implications for post-COVID complications	13
Ancestry affects the transcription of small mitochondrial RNAs in human lymphocytes	13
Role of mitophagy in pulmonary hypertension: Targeting the mechanism and pharmacological intervention	13
WITHDRAWN: Mitochondrial oxygen respiration is associated with loneliness in a sample of community-dwelling adults	13
Editorial Board	13
Fighting Parkinson’s disease: The return of the mitochondria	13
Altered brown adipose tissue mitochondrial function in newborn fragile X syndrome mice	13
Serum cell-free mitochondrial DNA under a highly standardized and controlled stress induction	13
Perceived association of mood and symptom severity in adults with mitochondrial diseases	13
Differentiation activates mitochondrial OPA1 processing in myoblast cell lines	12
Early cardiac mechanics abnormalities in patients with mitochondrial diseases	12
Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies	12
Auditory neuropathy spectrum disorder and related auditory features in patients with hearing loss associated with the MT-TS1 m.7471dup variant	12
Identifying the mitochondrial metabolism network by integration of machine learning and explainable artificial intelligence in skeletal muscle in type 2 diabetes	12
Receptor-mediated mitophagy: An emerging therapeutic target in acute kidney injury	12
URMD-Seq: A high-throughput method for scalable detection of ultra-rare mutations in the human mitochondrial genome	12
Type 1 diabetes mellitus: Inflammation, mitophagy, and mitochondrial function	12