OOIR: Observatory of International Research

Papers

(The TQCC of Mitochondrion is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
The role of mtDNA haplogroups on metabolic features in narcolepsy type 1	148
The multifaceted modulation of mitochondrial metabolism in tumorigenesis	133
Sequencing errors in Native American mitogenomes: Impact on clade definitions, haplogroup assignation, and beyond	67
Hsp90 and its mitochondrial homologue TRAP-1 independently regulate hypoxia adaptations in Caenorhabditis elegans	63
CMT2A-linked MFN2 mutation, T206I promotes mitochondrial hyperfusion and predisposes cells towards mitophagy	60
The tissue-specific nature of physiological zebrafish mitochondrial bioenergetics	55
Editorial Board	51
Mitofusin 2: The missing link between mtDNA maintenance defects and neurotransmitter disorders	44
ACAD9 treatment with bezafibrate and nicotinamide riboside temporarily stabilizes cardiomyopathy and lactic acidosis	39
Activation of multifunctional DNA repair APE1/Ref-1 enzyme by the dietary phytochemical Ferulic acid protects human neuroblastoma SH-SY5Y cells against Aβ(25–35)-induced oxidative stress and inflammat	38
Delivery of mitoceuticals or respiratory competent mitochondria to sites of neurotrauma	38
What can we do to optimize mitochondrial transplantation therapy for myocardial ischemia–reperfusion injury?	38
The role of mitochondrial genes in ischemia-reperfusion injury: A systematic review of experimental studies	36
Thyroid hormone enhances efficacy of cisplatin in lung cancer patients via down-regulating GLUT1 expression and reversing the Warburg effect	35
Editorial Board	35
Editorial Board	34
Reanalysis of mtDNA mutations of human primordial germ cells (PGCs) reveals NUMT contamination and suggests that selection in PGCs may be positive	32
Role of GM-CSF in regulating metabolism and mitochondrial functions critical to macrophage proliferation	32
Targeting the redox imbalance in mitochondria: A novel mode for cancer therapy	31
Mitochondria in biology and medicine – 2023	28
PhNR and peripapillary RNFL changes in Leber hereditary optic neuropathy with m.G11778A mutation	28
Paternal aging impacts mitochondrial DNA content and telomere length in mouse embryos	27
Mitophagy in depression: Pathophysiology and treatment targets	25
Mitochondrial density in skeletal and cardiac muscle	25
The war against Alzheimer, the mitochondrion strikes back!	24

Muscle-UCP3 in the regulation of energy metabolism	24
Mrs2-mediated mitochondrial magnesium uptake is essential for the regulation of MCU-mediated mitochondrial Ca2+ uptake and viability	24
Editorial Board	24
Pyridoxal-5-phosphate mitigates age-related metabolic imbalances in the rat heart through the H2S/AKT/GSK3β signaling axis	23
Genomic and non-genomic action of vitamin D on ion channels – Targeting mitochondria	22
Reactive oxygen species favors Varicellovirus bovinealpha 5 (BoAHV-5) replication in neural cells	22
Mitochondrial genome-derived circRNAs: Orphan epigenetic regulators in molecular biology	21
Identification of a novel m.3955G > A variant in MT-ND1 associated with Leigh syndrome	21
Decoding the nature and complexity of extracellular mtDNA: Types and implications for health and disease	21
Site-specific mitochondrial dysfunction in neurodegeneration	21
Exploring the role of mitochondria transfer/transplant and their long-non-coding RNAs in regenerative therapies for skin aging	21
TRPV4 acts as a mitochondrial Ca2+-importer and regulates mitochondrial temperature and metabolism	20
Mitochondrial transplantation therapy inhibits the proliferation of malignant hepatocellular carcinoma and its mechanism	20
Mitochondrial Irc3 helicase of the thermotolerant yeast Ogataea polymorpha displays dual DNA- and RNA-stimulated ATPase activity	20
Blood cell respiration rates and mtDNA copy number: A promising tool for the diagnosis of mitochondrial disease	20
Reviewing the mitochondrial dysfunction paradigm in rodent models as platforms for neuropsychiatric disease research	20
COVID-19 induced liver injury from a new perspective: Mitochondria	20
The maternal genetic history of tribal populations of Chhattisgarh, India	19
Impact of missense mutations on the structure–function relationship of human succinyl-CoA synthetase using in silico analysis	19
Understanding differential aspects of microdiffusion (channeling) in the Coenzyme Q and Cytochrome c regions of the mitochondrial respiratory system	19
Association analysis of mitochondrial DNA heteroplasmic variants: Methods and application	18
Urolithin-A supplementation alleviates sepsis-induced acute lung injury by reducing mitochondrial dysfunction and modulating macrophage polarization	17
Advancing mitochondria as a therapeutic agent	17
Interplay of mitochondria and diabetes: Unveiling novel therapeutic strategies	16
Serum TCA cycle metabolites in Lewy bodies dementia and Alzheimer's disease: Network analysis and cognitive prognosis	16
Mitochondria dysfunction and impaired response to oxidative stress promotes proteostasis disruption in aged human cells	16
2-Aminoethoxydiphenyl borate ameliorates mitochondrial dysfunctions in MPTP/MPP+ model of Parkinson’s disease	16
Application research of novel peptide mitochondrial-targeted antioxidant SS-31 in mitigating mitochondrial dysfunction	15
Mitochondrial oxidative stress in brain microvascular endothelial cells: Triggering blood-brain barrier disruption	15
An integrated multi-omics approach allowed ultra-rapid diagnosis of a deep intronic pathogenic variant in PDHX and precision treatment in a neonate critically ill with lactic acidosis	15
Newer mitochondrial dynamics and their role of calcium signalling in liver regeneration	15
Miro1 improves the exogenous engraftment efficiency and therapeutic potential of mitochondria transfer using Wharton's jelly mesenchymal stem cells	14
Mitochondrial bioenergetics of breast cancer	14
Corrigendum to “Comparison of whole genome sequencing and targeted sequencing for mitochondrial DNA” [Mitochondrion 58 (2021) 303–310]	14
Mitochondrial dysfunction and inflammasome activation in neurodegenerative diseases: Mechanisms and therapeutic implications	14
Prognostic value of circulating mitochondrial DNA in prostate cancer and underlying mechanism	14
Research progress on paternal mitochondrial inheritance: An overview	14
Kinetic characterization of respirasomes and free complex I from Yarrowia lipolytica	14
Neuroprotective compounds alter the expression of genes coding for proteins related to mitochondrial function in activated microglia	14
Targeting mitochondria with small molecules: A promising strategy for combating Parkinson’s disease	14
Whole genome sequencing followed by functional analysis of genomic deletion encompassing ERCC8 and NDUFAF2 genes in a non-consanguineous Indian family reveals dysfunctional mitochondrial bioenergetics	14
The biology of mitochondrial carrier homolog 2	14
Defining ER-mitochondria contact dynamics in Plasmodium falciparum by targeting component of phospholipid synthesis pathway, phosphatidylserine synthase (PfPSS)	13
Targeting the mitochondria in chronic respiratory diseases	13
WITHDRAWN: Mitochondrial oxygen respiration is associated with loneliness in a sample of community-dwelling adults	13
Selective and reversible disruption of mitochondrial inner membrane protein complexes by lipophilic cations	13
Fighting Parkinson’s disease: The return of the mitochondria	13
Visualization of mitophagy using LysoKK, a 7-nitro-2,1,3-benzoxadiazole-(arylpropyl)benzylamine derivative	13
The Parkinson’s disease-associated mutation LRRK2 G2385R alters mitochondrial biogenesis via the PGC-1α-TFAM pathway	13
RTN3 deficiency exacerbates cisplatin-induced acute kidney injury through the disruption of mitochondrial stability	13

Role of mitophagy in pulmonary hypertension: Targeting the mechanism and pharmacological intervention	12
Differentiation activates mitochondrial OPA1 processing in myoblast cell lines	12
Ancestry affects the transcription of small mitochondrial RNAs in human lymphocytes	12
Aromatic hydrocarbon receptors in mitochondrial biogenesis and function	12
Longitudinal changes in mitochondrial-associated measures and insulin resistance in youth with perinatally-acquired HIV in the U.S	12
Cancer/Testis Antigen 55 is required for cancer cell proliferation and mitochondrial DNA maintenance	12
Perceived association of mood and symptom severity in adults with mitochondrial diseases	12
Auditory neuropathy spectrum disorder and related auditory features in patients with hearing loss associated with the MT-TS1 m.7471dup variant	12
Altered brown adipose tissue mitochondrial function in newborn fragile X syndrome mice	12
Editorial Board	12
The constraints of allotopic expression	11
Receptor-mediated mitophagy: An emerging therapeutic target in acute kidney injury	11
Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies	11
Analysis of compound heterozygous and homozygous mutations found in peripheral subunits of human respiratory Complex I, NDUFS1, NDUFS2, NDUFS8 and NDUFV1, by modeling in the E. coli enzyme	11
Type 1 diabetes mellitus: Inflammation, mitophagy, and mitochondrial function	11
Miro1- a key player in β-cell function and mitochondrial dynamics under diabetes mellitus	11
Severe acute respiratory syndrome coronaviruses contributing to mitochondrial dysfunction: Implications for post-COVID complications	11
Sirtuin 3 and mitochondrial permeability transition pore (mPTP): A systematic review	10
Identifying the mitochondrial metabolism network by integration of machine learning and explainable artificial intelligence in skeletal muscle in type 2 diabetes	10
Recent trends of natural based therapeutics for mitochondria targeting in Alzheimer’s disease	10
Early cardiac mechanics abnormalities in patients with mitochondrial diseases	10
Transplantation of astrocyte-derived mitochondria into injured astrocytes has a protective effect following stretch injury	10
Mitochondria in aging and age-associated diseases	10
The impact of TK2 deficiency syndrome and its treatment by nucleoside therapy on quality of life	10
DDQ anti-aging properties expressed with improved mitophagy in mutant tau HT22 neuronal cells	10
MitoQuicLy: A high-throughput method for quantifying cell-free DNA from human plasma, serum, and saliva	10
HIV-1 gp120 protein promotes HAND through the calcineurin pathway activation	10
Machine learning-based 3D segmentation of mitochondria in polarized epithelial cells	10