OOIR: Observatory of International Research

Papers

(The TQCC of Mitochondrion is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Sequencing errors in Native American mitogenomes: Impact on clade definitions, haplogroup assignation, and beyond	220
The tissue-specific nature of physiological zebrafish mitochondrial bioenergetics	102
The multifaceted modulation of mitochondrial metabolism in tumorigenesis	70
CMT2A-linked MFN2 mutation, T206I promotes mitochondrial hyperfusion and predisposes cells towards mitophagy	64
Role of oxidative stress in the susceptibility to mitophagy of the skin fibroblasts and iPSC-derived neurons of patients with MERRF syndrome	61
What can we do to optimize mitochondrial transplantation therapy for myocardial ischemia–reperfusion injury?	58
A Tunisian POLG mutation expands the clinical spectrum of POLG-related disorders	58
ACAD9 treatment with bezafibrate and nicotinamide riboside temporarily stabilizes cardiomyopathy and lactic acidosis	45
Editorial Board	45
Delivery of mitoceuticals or respiratory competent mitochondria to sites of neurotrauma	41
Mitochondrial density in skeletal and cardiac muscle	39
The role of mitochondrial genes in ischemia-reperfusion injury: A systematic review of experimental studies	39
Activation of multifunctional DNA repair APE1/Ref-1 enzyme by the dietary phytochemical Ferulic acid protects human neuroblastoma SH-SY5Y cells against Aβ(25–35)-induced oxidative stress and inflammat	39
Editorial Board	36
PhNR and peripapillary RNFL changes in Leber hereditary optic neuropathy with m.G11778A mutation	35
Thyroid hormone enhances efficacy of cisplatin in lung cancer patients via down-regulating GLUT1 expression and reversing the Warburg effect	35
Reanalysis of mtDNA mutations of human primordial germ cells (PGCs) reveals NUMT contamination and suggests that selection in PGCs may be positive	33
PKM2 is a key regulator of cardiac lipid metabolism in mice	31
Mrs2-mediated mitochondrial magnesium uptake is essential for the regulation of MCU-mediated mitochondrial Ca2+ uptake and viability	30
Mitochondria in biology and medicine – 2023	30
Paternal aging impacts mitochondrial DNA content and telomere length in mouse embryos	28
Reactive oxygen species favors Varicellovirus bovinealpha 5 (BoAHV-5) replication in neural cells	28
The evolving landscape of mitochondrial base editing: advances in precision, modeling, and therapeutic potential	27
Pyridoxal-5-phosphate mitigates age-related metabolic imbalances in the rat heart through the H2S/AKT/GSK3β signaling axis	26
Mitochondrial genome-derived circRNAs: Orphan epigenetic regulators in molecular biology	26

Muscle-UCP3 in the regulation of energy metabolism	25
Genomic and non-genomic action of vitamin D on ion channels – Targeting mitochondria	25
Mitochondrial Irc3 helicase of the thermotolerant yeast Ogataea polymorpha displays dual DNA- and RNA-stimulated ATPase activity	24
TRPV4 acts as a mitochondrial Ca2+-importer and regulates mitochondrial temperature and metabolism	24
Exploring the role of mitochondria transfer/transplant and their long-non-coding RNAs in regenerative therapies for skin aging	24
COVID-19 induced liver injury from a new perspective: Mitochondria	23
COXFA4L3 enhances mitochondrial complex IV function to boost ATP synthesis and drive sperm motility	23
Intravenous mitochondrial transplantation as an adjunctive therapy for dilated cardiomyopathy	22
Decoding the nature and complexity of extracellular mtDNA: Types and implications for health and disease	22
Mitochondrial transplantation therapy inhibits the proliferation of malignant hepatocellular carcinoma and its mechanism	22
Unmasking NLRX1: Exploring the broadening biological landscape of a mysterious mitochondrial sensor	21
The maternal genetic history of tribal populations of Chhattisgarh, India	21
Understanding differential aspects of microdiffusion (channeling) in the Coenzyme Q and Cytochrome c regions of the mitochondrial respiratory system	21
Impact of missense mutations on the structure–function relationship of human succinyl-CoA synthetase using in silico analysis	21
Advancing mitochondria as a therapeutic agent	21
2-Aminoethoxydiphenyl borate ameliorates mitochondrial dysfunctions in MPTP/MPP+ model of Parkinson’s disease	20
Editorial Board	20
Mitochondria dysfunction and impaired response to oxidative stress promotes proteostasis disruption in aged human cells	19
Serum TCA cycle metabolites in Lewy bodies dementia and Alzheimer's disease: Network analysis and cognitive prognosis	19
Association analysis of mitochondrial DNA heteroplasmic variants: Methods and application	19
Targeted mitochondrial metabolism for anti-tumor therapy	18
Interplay of mitochondria and diabetes: Unveiling novel therapeutic strategies	18
Mitochondrial Transcription: A click-chemistry derived detection methodology forgoing the use of radiation in in vitro analyses	18
Mitochondrial oxidative stress in brain microvascular endothelial cells: Triggering blood-brain barrier disruption	18
Urolithin-A supplementation alleviates sepsis-induced acute lung injury by reducing mitochondrial dysfunction and modulating macrophage polarization	18
Newer mitochondrial dynamics and their role of calcium signalling in liver regeneration	18
The biology of mitochondrial carrier homolog 2	17
Application research of novel peptide mitochondrial-targeted antioxidant SS-31 in mitigating mitochondrial dysfunction	17
An integrated multi-omics approach allowed ultra-rapid diagnosis of a deep intronic pathogenic variant in PDHX and precision treatment in a neonate critically ill with lactic acidosis	16
Kinetic characterization of respirasomes and free complex I from Yarrowia lipolytica	16
Mitochondrial quality control in exercise-mitigated muscular atrophy	16
Whole genome sequencing followed by functional analysis of genomic deletion encompassing ERCC8 and NDUFAF2 genes in a non-consanguineous Indian family reveals dysfunctional mitochondrial bioenergetics	15
Mitochondrial dysfunction and inflammasome activation in neurodegenerative diseases: Mechanisms and therapeutic implications	15
Novel mutations in MTERF3: First report of a new genetic cause in two Chinese patients with developmental delay, intermittent hypoglycemia and metabolic acidosis	15
Neuroprotective compounds alter the expression of genes coding for proteins related to mitochondrial function in activated microglia	15
Prognostic value of circulating mitochondrial DNA in prostate cancer and underlying mechanism	15
Mitochondrial bioenergetics of breast cancer	15
RTN3 deficiency exacerbates cisplatin-induced acute kidney injury through the disruption of mitochondrial stability	14
Targeting mitochondria with small molecules: A promising strategy for combating Parkinson’s disease	14
Targeting the mitochondria in chronic respiratory diseases	14
Research progress on paternal mitochondrial inheritance: An overview	14
The Parkinson’s disease-associated mutation LRRK2 G2385R alters mitochondrial biogenesis via the PGC-1α-TFAM pathway	14
Mitochondrial dysfunction–induced PANoptosis: Mechanisms, triggers, and disease implications	14
Selective and reversible disruption of mitochondrial inner membrane protein complexes by lipophilic cations	14
Miro1 improves the exogenous engraftment efficiency and therapeutic potential of mitochondria transfer using Wharton's jelly mesenchymal stem cells	14
Role of mitophagy in pulmonary hypertension: Targeting the mechanism and pharmacological intervention	13
Severe acute respiratory syndrome coronaviruses contributing to mitochondrial dysfunction: Implications for post-COVID complications	13
Perceived association of mood and symptom severity in adults with mitochondrial diseases	13
Defining ER-mitochondria contact dynamics in Plasmodium falciparum by targeting component of phospholipid synthesis pathway, phosphatidylserine synthase (PfPSS)	13
URMD-Seq: A high-throughput method for scalable detection of ultra-rare mutations in the human mitochondrial genome	13

Ancestry affects the transcription of small mitochondrial RNAs in human lymphocytes	13
WITHDRAWN: Mitochondrial oxygen respiration is associated with loneliness in a sample of community-dwelling adults	13
Longitudinal changes in mitochondrial-associated measures and insulin resistance in youth with perinatally-acquired HIV in the U.S	13
Altered brown adipose tissue mitochondrial function in newborn fragile X syndrome mice	13
Editorial Board	13
Serum cell-free mitochondrial DNA under a highly standardized and controlled stress induction	12
Auditory neuropathy spectrum disorder and related auditory features in patients with hearing loss associated with the MT-TS1 m.7471dup variant	12
Receptor-mediated mitophagy: An emerging therapeutic target in acute kidney injury	12
Type 1 diabetes mellitus: Inflammation, mitophagy, and mitochondrial function	12
Differentiation activates mitochondrial OPA1 processing in myoblast cell lines	12
Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies	12