Mitochondrion

Article	Citations
Sequencing errors in Native American mitogenomes: Impact on clade definitions, haplogroup assignation, and beyond	210
The tissue-specific nature of physiological zebrafish mitochondrial bioenergetics	101
The multifaceted modulation of mitochondrial metabolism in tumorigenesis	67
CMT2A-linked MFN2 mutation, T206I promotes mitochondrial hyperfusion and predisposes cells towards mitophagy	65
A Tunisian POLG mutation expands the clinical spectrum of POLG-related disorders	62
Editorial Board	59
Delivery of mitoceuticals or respiratory competent mitochondria to sites of neurotrauma	57
Activation of multifunctional DNA repair APE1/Ref-1 enzyme by the dietary phytochemical Ferulic acid protects human neuroblastoma SH-SY5Y cells against Aβ(25–35)-induced oxidative stress and inflammat	54
ACAD9 treatment with bezafibrate and nicotinamide riboside temporarily stabilizes cardiomyopathy and lactic acidosis	45
What can we do to optimize mitochondrial transplantation therapy for myocardial ischemia–reperfusion injury?	43
The role of mitochondrial genes in ischemia-reperfusion injury: A systematic review of experimental studies	41
Mitochondrial density in skeletal and cardiac muscle	40
PhNR and peripapillary RNFL changes in Leber hereditary optic neuropathy with m.G11778A mutation	38
Editorial Board	38
Editorial Board	38
Thyroid hormone enhances efficacy of cisplatin in lung cancer patients via down-regulating GLUT1 expression and reversing the Warburg effect	35
The war against Alzheimer, the mitochondrion strikes back!	34
Paternal aging impacts mitochondrial DNA content and telomere length in mouse embryos	34
Reanalysis of mtDNA mutations of human primordial germ cells (PGCs) reveals NUMT contamination and suggests that selection in PGCs may be positive	33
PKM2 is a key regulator of cardiac lipid metabolism in mice	30
Mitochondria in biology and medicine – 2023	30
Mrs2-mediated mitochondrial magnesium uptake is essential for the regulation of MCU-mediated mitochondrial Ca2+ uptake and viability	29
Reactive oxygen species favors Varicellovirus bovinealpha 5 (BoAHV-5) replication in neural cells	28
Site-specific mitochondrial dysfunction in neurodegeneration	28
The evolving landscape of mitochondrial base editing: advances in precision, modeling, and therapeutic potential	28

Genomic and non-genomic action of vitamin D on ion channels – Targeting mitochondria	26
Pyridoxal-5-phosphate mitigates age-related metabolic imbalances in the rat heart through the H2S/AKT/GSK3β signaling axis	26
Muscle-UCP3 in the regulation of energy metabolism	25
Mitochondrial genome-derived circRNAs: Orphan epigenetic regulators in molecular biology	25
TRPV4 acts as a mitochondrial Ca2+-importer and regulates mitochondrial temperature and metabolism	24
Mitochondrial Irc3 helicase of the thermotolerant yeast Ogataea polymorpha displays dual DNA- and RNA-stimulated ATPase activity	24
Intravenous mitochondrial transplantation as an adjunctive therapy for dilated cardiomyopathy	24
Exploring the role of mitochondria transfer/transplant and their long-non-coding RNAs in regenerative therapies for skin aging	24
Reviewing the mitochondrial dysfunction paradigm in rodent models as platforms for neuropsychiatric disease research	23
COXFA4L3 enhances mitochondrial complex IV function to boost ATP synthesis and drive sperm motility	23
COVID-19 induced liver injury from a new perspective: Mitochondria	22
Mitochondrial transplantation therapy inhibits the proliferation of malignant hepatocellular carcinoma and its mechanism	22
Decoding the nature and complexity of extracellular mtDNA: Types and implications for health and disease	22
Impact of missense mutations on the structure–function relationship of human succinyl-CoA synthetase using in silico analysis	21
Newer mitochondrial dynamics and their role of calcium signalling in liver regeneration	21
The maternal genetic history of tribal populations of Chhattisgarh, India	21
Advancing mitochondria as a therapeutic agent	20
Association analysis of mitochondrial DNA heteroplasmic variants: Methods and application	20
Unmasking NLRX1: Exploring the broadening biological landscape of a mysterious mitochondrial sensor	20
Editorial Board	20
Urolithin-A supplementation alleviates sepsis-induced acute lung injury by reducing mitochondrial dysfunction and modulating macrophage polarization	19
Understanding differential aspects of microdiffusion (channeling) in the Coenzyme Q and Cytochrome c regions of the mitochondrial respiratory system	19
2-Aminoethoxydiphenyl borate ameliorates mitochondrial dysfunctions in MPTP/MPP+ model of Parkinson’s disease	19
Mitochondria dysfunction and impaired response to oxidative stress promotes proteostasis disruption in aged human cells	19
Targeted mitochondrial metabolism for anti-tumor therapy	18
Mitochondrial oxidative stress in brain microvascular endothelial cells: Triggering blood-brain barrier disruption	18
Kinetic characterization of respirasomes and free complex I from Yarrowia lipolytica	18
Interplay of mitochondria and diabetes: Unveiling novel therapeutic strategies	18
Serum TCA cycle metabolites in Lewy bodies dementia and Alzheimer's disease: Network analysis and cognitive prognosis	18
Mitochondrial dysfunction and inflammasome activation in neurodegenerative diseases: Mechanisms and therapeutic implications	17
The biology of mitochondrial carrier homolog 2	17
Application research of novel peptide mitochondrial-targeted antioxidant SS-31 in mitigating mitochondrial dysfunction	17
Mitochondrial Transcription: A click-chemistry derived detection methodology forgoing the use of radiation in in vitro analyses	17
An integrated multi-omics approach allowed ultra-rapid diagnosis of a deep intronic pathogenic variant in PDHX and precision treatment in a neonate critically ill with lactic acidosis	17
Mitochondrial quality control in exercise-mitigated muscular atrophy	17
Novel mutations in MTERF3: First report of a new genetic cause in two Chinese patients with developmental delay, intermittent hypoglycemia and metabolic acidosis	16
Whole genome sequencing followed by functional analysis of genomic deletion encompassing ERCC8 and NDUFAF2 genes in a non-consanguineous Indian family reveals dysfunctional mitochondrial bioenergetics	16
Mitochondrial bioenergetics of breast cancer	15
Targeting the mitochondria in chronic respiratory diseases	15
Neuroprotective compounds alter the expression of genes coding for proteins related to mitochondrial function in activated microglia	15
Mitochondrial dysfunction–induced PANoptosis: Mechanisms, triggers, and disease implications	15
Prognostic value of circulating mitochondrial DNA in prostate cancer and underlying mechanism	15
Miro1 improves the exogenous engraftment efficiency and therapeutic potential of mitochondria transfer using Wharton's jelly mesenchymal stem cells	14
Selective and reversible disruption of mitochondrial inner membrane protein complexes by lipophilic cations	14
The Parkinson’s disease-associated mutation LRRK2 G2385R alters mitochondrial biogenesis via the PGC-1α-TFAM pathway	14
RTN3 deficiency exacerbates cisplatin-induced acute kidney injury through the disruption of mitochondrial stability	14
Defining ER-mitochondria contact dynamics in Plasmodium falciparum by targeting component of phospholipid synthesis pathway, phosphatidylserine synthase (PfPSS)	14
Research progress on paternal mitochondrial inheritance: An overview	14
Targeting mitochondria with small molecules: A promising strategy for combating Parkinson’s disease	14
Role of mitophagy in pulmonary hypertension: Targeting the mechanism and pharmacological intervention	13

WITHDRAWN: Mitochondrial oxygen respiration is associated with loneliness in a sample of community-dwelling adults	13
Editorial Board	13
Fighting Parkinson’s disease: The return of the mitochondria	13
Altered brown adipose tissue mitochondrial function in newborn fragile X syndrome mice	13
Serum cell-free mitochondrial DNA under a highly standardized and controlled stress induction	13
Perceived association of mood and symptom severity in adults with mitochondrial diseases	13
Longitudinal changes in mitochondrial-associated measures and insulin resistance in youth with perinatally-acquired HIV in the U.S	13
Cancer/Testis Antigen 55 is required for cancer cell proliferation and mitochondrial DNA maintenance	13
Severe acute respiratory syndrome coronaviruses contributing to mitochondrial dysfunction: Implications for post-COVID complications	13
Ancestry affects the transcription of small mitochondrial RNAs in human lymphocytes	13
Identifying the mitochondrial metabolism network by integration of machine learning and explainable artificial intelligence in skeletal muscle in type 2 diabetes	12
Auditory neuropathy spectrum disorder and related auditory features in patients with hearing loss associated with the MT-TS1 m.7471dup variant	12
Receptor-mediated mitophagy: An emerging therapeutic target in acute kidney injury	12
URMD-Seq: A high-throughput method for scalable detection of ultra-rare mutations in the human mitochondrial genome	12
Type 1 diabetes mellitus: Inflammation, mitophagy, and mitochondrial function	12
Early cardiac mechanics abnormalities in patients with mitochondrial diseases	12
Differentiation activates mitochondrial OPA1 processing in myoblast cell lines	12
Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies	12
Analysis of compound heterozygous and homozygous mutations found in peripheral subunits of human respiratory Complex I, NDUFS1, NDUFS2, NDUFS8 and NDUFV1, by modeling in the E. coli enzyme	11
Transplantation of astrocyte-derived mitochondria into injured astrocytes has a protective effect following stretch injury	11
MitoQuicLy: A high-throughput method for quantifying cell-free DNA from human plasma, serum, and saliva	11
Mitochondrial tRNA variants in 811 Chinese probands with Leber’s hereditary optic neuropathy	10
PKD regulates mitophagy to prevent oxidative stress and mitochondrial dysfunction during mouse oocyte maturation	10
DDQ anti-aging properties expressed with improved mitophagy in mutant tau HT22 neuronal cells	10
Machine learning-based 3D segmentation of mitochondria in polarized epithelial cells	10
The impact of TK2 deficiency syndrome and its treatment by nucleoside therapy on quality of life	10
The constraints of allotopic expression	10
Sirtuin 3 and mitochondrial permeability transition pore (mPTP): A systematic review	10
Dysregulated iron homeostasis Drives mitochondrial Injury and ferroptosis susceptibility in MELAS fibroblasts	10
Associations of mitochondrial genomic variation with successful neurological aging	10
Mitochondria in aging and age-associated diseases	10
Miro1- a key player in β-cell function and mitochondrial dynamics under diabetes mellitus	10
Recent trends of natural based therapeutics for mitochondria targeting in Alzheimer’s disease	9
Decoding mitochondrial quality control mechanisms: Identifying treatment targets for enhanced cellular health	9
HIV-1 gp120 protein promotes HAND through the calcineurin pathway activation	9
Mitochondrial iron overload is associated with lysosomal dysfunction-mediated mitophagy impairment in the heart of Friedreich’s ataxia	9
Mitochondrial mechanisms in Treg cell regulation: Implications for immunotherapy and disease treatment	9
Transcriptional activation by MNRR1 is effected by recruiting p300 and can be induced by minimal peptides	9
Mitochondrial dynamics and mitochondrial autophagy: Molecular structure, orchestrating mechanism and related disorders	9
SIRT6 suppresses colon cancer growth by inducing apoptosis and autophagy through transcriptionally down-regulating Survivin	8
The maternal genetic origin and diversity of the extant populations of the Ladakh region in India	8
Assessment of mitochondrial DNA copy number variation relative to nuclear DNA quantity between different tissues	8
Role of mitochondrial potassium channels in ageing	8
GenEye24: Novel rapid screening test for the top-3 Leber’s Hereditary Optic Neuropathy pathogenic sequence variants	8
Deciphering the role of MitomiRs in cancer: A comprehensive review	8
β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence	8
Probability of Mitochondrial DNA heteroplasmy in different tissues from European populations	8
Understanding the molecular basis of anti-fibrotic potential of intranasal curcumin and its association with mitochondrial homeostasis in silica-exposed mice	8
The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches	8
Editorial Board	8
Hemispheric analysis of mitochondrial Complex I and II activity in the mouse model of ischemia-reperfusion-induced injury	8
Mitochondrial and metabolic features of salugenesis and the healing cycle	8
Extracellular vesicles as carriers for mitochondria: Biological functions and clinical applications	8
Role of Rmd9p in 3′-end processing of mitochondrial 15S rRNA in Saccharomyces cerevisiae	8
Mitochondrial bioenergetics and cytometric characterization of a synaptosomal preparation from mouse brain cortex	8
Editorial Board	7
Relationships of mitochondrial DNA mutations and select clinical diagnoses in perinatally HIV- and ART-exposed uninfected children	7
Different platforms for mitomiRs in mitochondria: Emerging facets in regulation of mitochondrial functions	7
Machine learning to predict mitochondrial diseases by phenotypes	7
Clinical and genetic spectrum of mitochondrial DNA depletion syndromes: A report of 6 cases with 4 novel variants	7
Large-scale screens identify a 19-Gene MitoScore for improved risk assessment in acute myeloid leukemia	7
Mitochondrial DNA mutation pathogenicity score and neurocognitive performance in persons with HIV	7
Mitochondrial Mechanisms in Temozolomide Resistance: Unraveling the Complex Interplay and Therapeutic Strategies in Glioblastoma	7
Mitochondrial DNA abundance and circulating metabolomic profiling: Multivariable-adjusted and Mendelian randomization analyses in UK Biobank	7
Endurance swimming exacerbates mitochondrial myopathy in mice with high mtDNA deletions	7
Interplay of mitochondria-associated membrane proteins and autophagy: Implications in neurodegeneration	6
Patient-derived TWNK variants recapitulate multisystem Perrault syndrome pathology in a mouse model	6
Beneficial effects of mitophagy enhancers on amyloid beta-induced mitochondrial and synaptic toxicities in Alzheimer’s disease	6
The mitochondrial chaperone TRAP-1 regulates the glutamine metabolism in tumor cells	6
Revolutionizing cellular energy: The convergence of mitochondrial dynamics and delivery technologies	6
mitoPADdb: A database of mitochondrial proteins associated with diseases	6
AutomAted RepeaT Identifier (AARTI): A tool to identify common, polymorphic, and unique microsatellites	6
Mitochondria transfer from myocytes to endothelial cells promotes angiogenesis in skeletal muscle	6
Mitochondrial dysfunction in diabetic neuropathy: Impaired mitophagy triggers NLRP3 inflammasome	6
Telomere length determines the mitochondrial copy number in blastocyst-stage embryos	6
Image-based quantification of mitochondrial iron uptake via Mitoferrin-2	6
Mitochondrial transplantation: Triumphs, challenges, and impacts on nuclear genome remodelling	6
Positive regulation of endothelial Tom70 by metformin as a new mechanism against cardiac microvascular injury in diabetes	6
ER stress-associated transcription factor CREB3 is essential for normal Ca2+, ATP, and ROS homeostasis	6
Erodible thermogelling hydrogels for localized mitochondrial transplantation to the spinal cord	6

Editorial Board	6
TNF-α-mediated down-regulation of mitochondrial transcription factors: Rescue by Angiotensin-(1–7) peptide	6
NUDT6 and NUDT9, two mitochondrial members of the NUDIX family, have distinct hydrolysis activities	6
The Schizosaccharomyces pombe DEAD-box protein Mss116 is required for mitoribosome assembly and mitochondrial translation	6
The mitochondrial protein TMEM177 fine-tunes mammalian cytochrome c oxidase assembly	5
A novel, conserved and possibly functional motif “WHWGHTW” in mitochondrial transcription across Bilateria	5
Ancient mitogenomes suggest complex maternal history of one of the oldest settlements of western India	5
A comprehensive perspective of Huntington’s disease and mitochondrial dysfunction	5
Understanding the neuronal synapse and challenges associated with the mitochondrial dysfunction in mild cognitive impairment and Alzheimer’s disease	5
Ultrastructural and functional recovery of mitochondria and improved developmental competence by melatonin in oxidatively stressed porcine oocytes	5
Mitochondrial dynamics related neurovascular approaches in cerebral ischemic injury	5
Regulation of mitochondrial network homeostasis by O-GlcNAcylation	5
A 3-hit metabolic signaling model for the core symptoms of autism spectrum disorder	5
Corrigendum to “Laurus nobilis ethanolic extract attenuates hyperglycemia and hyperinsulinemia-induced insulin resistance in HepG2 cell line through the reduction of oxidative stress and improvement o	5
Cyt b gene as a valid molecular authentication marker of cow leathers	5
Iron chelation mitigates mitochondrial dysfunction and oxidative stress by enhancing nrf2-mediated antioxidant responses in the renal cortex of a murine model of type 2 diabetes	5
Neuroprotective effect of autologous mitochondrial transplantation against global ischemia/reperfusion injury in a rat model of cardiac arrest	5
Editorial Board	5
Mitochondrial DNA haplogroup, genetic ancestry, and susceptibility to Ewing sarcoma	5
SDHAF2 facilitates mitochondrial respiration through stabilizing succinate dehydrogenase and cytochrome c oxidase assemblies	5
Pearson syndrome with atypical presentation of short stature and atypical limb proportions – First reported case in Slovakia	4
Mitochondrial ribosomal protein genes connected with Alzheimer’s and tellurite toxicity	4
Mitochondrial dysfunction, a weakest link of network of aging, relation to innate intramitochondrial immunity of DNA recognition receptors	4
Substitution of leucine by glutamate perturbs VopE localization to mitochondria: Lessons from yeast model system	4
Mitochondrial functioning in Rheumatoid arthritis modulated by estrogen: Evidence-based insight into the sex-based influence on mitochondria and disease	4
Transplanting mitochondria from gastric epithelial cells reduces the malignancy of gastric cancer	4
Complete mitochondrial DNA profile in stroke: A geographical matched case-control study in Spanish population	4
Augmented Parkin-dependent mitophagy underlies the hepatoprotective effect of remote ischemic conditioning used prior to hemorrhagic shock	4
Long read mitochondrial genome sequencing using Cas9-guided adaptor ligation	4
Role of mitochondrial dysfunction in the pathogenesis of rheumatoid arthritis: Looking closely at fibroblast- like synoviocytes	4
Scientific investigation of non-coding RNAs in mitochondrial epigenetic and aging disorders: Current nanoengineered approaches for their therapeutic improvement	4
Precise annotation of Drosophila mitochondrial genomes leads to insights into AT-rich regions	4
Editorial Board	4
Partial inhibition of mitochondrial-linked pyrimidine synthesis increases tumorigenic potential and lysosome accumulation	4
Krebs cycle derivatives, dimethyl fumarate and itaconate, control metabolic reprogramming in inflammatory human microglia cell line	4
The multifaceted effects of mitochondria in kidney diseases	4
Dysregulation of RUNX1 isoforms drives mitochondrial defects during neural differentiation in down syndrome	4
Phenotypic description and functional characterization of the mitochondrial disease associated with the SFXN4 gene	4
Cell-penetrating peptides with nanoparticles hybrid delivery vectors and their uptake pathways	4
Editorial Board	4
Simultaneous extraction and quantification of circulating mitochondrial and nuclear DNA using a single plasma sample to predict specific molecular diagnostic implications	4
Outlier maternal haplogroups N5 and X2 and their potential role in elevated tuberculosis prevalence among the Sahariya tribe	4
Mitochondrial transfer from mesenchymal stem cells: Mechanisms and functions	4