Mitochondrion

Papers
(The median citation count of Mitochondrion is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
The role of mtDNA haplogroups on metabolic features in narcolepsy type 1137
Mitochondrial DNA mutations do not impact early human embryonic development131
The tissue-specific nature of physiological zebrafish mitochondrial bioenergetics129
CMT2A-linked MFN2 mutation, T206I promotes mitochondrial hyperfusion and predisposes cells towards mitophagy91
Hsp90 and its mitochondrial homologue TRAP-1 independently regulate hypoxia adaptations in Caenorhabditis elegans58
Mitochondrial calcium signaling in the brain and its modulation by neurotropic viruses57
Sequencing errors in Native American mitogenomes: Impact on clade definitions, haplogroup assignation, and beyond49
The multifaceted modulation of mitochondrial metabolism in tumorigenesis49
Endoplasmic reticulum & mitochondrial calcium homeostasis: The interplay with viruses48
Editorial Board48
Comparison of whole genome sequencing and targeted sequencing for mitochondrial DNA46
What can we do to optimize mitochondrial transplantation therapy for myocardial ischemia–reperfusion injury?45
Mitofusin 2: The missing link between mtDNA maintenance defects and neurotransmitter disorders43
Activation of multifunctional DNA repair APE1/Ref-1 enzyme by the dietary phytochemical Ferulic acid protects human neuroblastoma SH-SY5Y cells against Aβ(25–35)-induced oxidative stress and inflammat38
Delivery of mitoceuticals or respiratory competent mitochondria to sites of neurotrauma37
Mrs2-mediated mitochondrial magnesium uptake is essential for the regulation of MCU-mediated mitochondrial Ca2+ uptake and viability37
ACAD9 treatment with bezafibrate and nicotinamide riboside temporarily stabilizes cardiomyopathy and lactic acidosis37
The mitochondrial-derived peptide MOTS-c promotes homeostasis in aged human placenta-derived mesenchymal stem cells in vitro35
Role of GM-CSF in regulating metabolism and mitochondrial functions critical to macrophage proliferation33
Targeting the redox imbalance in mitochondria: A novel mode for cancer therapy31
Mitophagy in depression: Pathophysiology and treatment targets31
Editorial Board31
The role of mitochondrial genes in ischemia-reperfusion injury: A systematic review of experimental studies30
Editorial Board30
Thyroid hormone enhances efficacy of cisplatin in lung cancer patients via down-regulating GLUT1 expression and reversing the Warburg effect30
Mitochondrial density in skeletal and cardiac muscle30
PhNR and peripapillary RNFL changes in Leber hereditary optic neuropathy with m.G11778A mutation30
Paternal aging impacts mitochondrial DNA content and telomere length in mouse embryos29
The war against Alzheimer, the mitochondrion strikes back!28
Reanalysis of mtDNA mutations of human primordial germ cells (PGCs) reveals NUMT contamination and suggests that selection in PGCs may be positive28
Editorial Board27
Mitochondria in biology and medicine – 202327
Pyridoxal-5-phosphate mitigates age-related metabolic imbalances in the rat heart through the H2S/AKT/GSK3β signaling axis25
Reactive oxygen species favors Varicellovirus bovinealpha 5 (BoAHV-5) replication in neural cells24
Genomic and non-genomic action of vitamin D on ion channels – Targeting mitochondria23
Site-specific mitochondrial dysfunction in neurodegeneration23
Mitochondrial genome-derived circRNAs: Orphan epigenetic regulators in molecular biology23
Ethylmalonic encephalopathy ETHE1 p. D165H mutation alters the mitochondrial function in human skeletal muscle proteome22
Identification of a novel m.3955G > A variant in MT-ND1 associated with Leigh syndrome22
Mitochondrion-driven nephroprotective mechanisms of novel glucose lowering medications21
Reviving mitochondrial bioenergetics: A relevant approach in epilepsy21
Extracellular mitochondria in the cerebrospinal fluid (CSF): Potential types and key roles in central nervous system (CNS) physiology and pathogenesis20
TRPV4 acts as a mitochondrial Ca2+-importer and regulates mitochondrial temperature and metabolism20
Muscle-UCP3 in the regulation of energy metabolism20
Circumventing the Crabtree effect in cell culture: A systematic review19
Exploring the role of mitochondria transfer/transplant and their long-non-coding RNAs in regenerative therapies for skin aging19
Mitochondrial Irc3 helicase of the thermotolerant yeast Ogataea polymorpha displays dual DNA- and RNA-stimulated ATPase activity19
Blood cell respiration rates and mtDNA copy number: A promising tool for the diagnosis of mitochondrial disease18
Reviewing the mitochondrial dysfunction paradigm in rodent models as platforms for neuropsychiatric disease research18
Decoding the nature and complexity of extracellular mtDNA: Types and implications for health and disease18
Impact of missense mutations on the structure–function relationship of human succinyl-CoA synthetase using in silico analysis18
Mitochondrial transplantation therapy inhibits the proliferation of malignant hepatocellular carcinoma and its mechanism18
COVID-19 induced liver injury from a new perspective: Mitochondria18
The maternal genetic history of tribal populations of Chhattisgarh, India17
Advancing mitochondria as a therapeutic agent17
Understanding differential aspects of microdiffusion (channeling) in the Coenzyme Q and Cytochrome c regions of the mitochondrial respiratory system17
Interplay of mitochondria and diabetes: Unveiling novel therapeutic strategies16
Mitochondria dysfunction and impaired response to oxidative stress promotes proteostasis disruption in aged human cells16
Association analysis of mitochondrial DNA heteroplasmic variants: Methods and application16
Mitochondrial oxidative stress in brain microvascular endothelial cells: Triggering blood-brain barrier disruption16
Serum TCA cycle metabolites in Lewy bodies dementia and Alzheimer's disease: Network analysis and cognitive prognosis16
2-Aminoethoxydiphenyl borate ameliorates mitochondrial dysfunctions in MPTP/MPP+ model of Parkinson’s disease16
An integrated multi-omics approach allowed ultra-rapid diagnosis of a deep intronic pathogenic variant in PDHX and precision treatment in a neonate critically ill with lactic acidosis15
Editorial Board15
Neuroprotective compounds alter the expression of genes coding for proteins related to mitochondrial function in activated microglia15
Newer mitochondrial dynamics and their role of calcium signalling in liver regeneration15
Corrigendum to “Comparison of whole genome sequencing and targeted sequencing for mitochondrial DNA” [Mitochondrion 58 (2021) 303–310]15
Metabolic abnormality in acute stroke-like lesion and its relationship with focal cerebral blood flow in patients with MELAS: Evidence from proton MR spectroscopy and arterial spin labeling15
Prognostic value of circulating mitochondrial DNA in prostate cancer and underlying mechanism15
The biology of mitochondrial carrier homolog 215
Mitochondrial dysfunction and inflammasome activation in neurodegenerative diseases: Mechanisms and therapeutic implications15
Whole genome sequencing followed by functional analysis of genomic deletion encompassing ERCC8 and NDUFAF2 genes in a non-consanguineous Indian family reveals dysfunctional mitochondrial bioenergetics15
Application research of novel peptide mitochondrial-targeted antioxidant SS-31 in mitigating mitochondrial dysfunction15
Polysulfide inhibits hypoxia-elicited hypoxia-inducible factor activation in a mitochondria-dependent manner14
Miro1 improves the exogenous engraftment efficiency and therapeutic potential of mitochondria transfer using Wharton's jelly mesenchymal stem cells14
Research progress on paternal mitochondrial inheritance: An overview14
Stressed mitochondria: A target to intrude alzheimer’s disease14
Mitochondrial bioenergetics of breast cancer14
Targeting mitochondria with small molecules: A promising strategy for combating Parkinson’s disease14
RTN3 deficiency exacerbates cisplatin-induced acute kidney injury through the disruption of mitochondrial stability14
HERMES: An improved method to test mitochondrial genome molecular synapomorphies among clades14
Visualization of mitophagy using LysoKK, a 7-nitro-2,1,3-benzoxadiazole-(arylpropyl)benzylamine derivative14
Mitochondrial N-methyl-d-aspartate receptor activation enhances bioenergetics by calcium-dependent and –Independent mechanisms14
Defining ER-mitochondria contact dynamics in Plasmodium falciparum by targeting component of phospholipid synthesis pathway, phosphatidylserine synthase (PfPSS)13
Selective and reversible disruption of mitochondrial inner membrane protein complexes by lipophilic cations13
The Parkinson’s disease-associated mutation LRRK2 G2385R alters mitochondrial biogenesis via the PGC-1α-TFAM pathway13
Fighting Parkinson’s disease: The return of the mitochondria13
Targeting the mitochondria in chronic respiratory diseases13
Editorial Board12
Type 1 diabetes mellitus: Inflammation, mitophagy, and mitochondrial function12
Cancer/Testis Antigen 55 is required for cancer cell proliferation and mitochondrial DNA maintenance12
Severe acute respiratory syndrome coronaviruses contributing to mitochondrial dysfunction: Implications for post-COVID complications12
WITHDRAWN: Mitochondrial oxygen respiration is associated with loneliness in a sample of community-dwelling adults12
Comparative mitogenomics of Agaricomycetes: Diversity, abundance, impact and coding potential of putative open-reading frames12
Receptor-mediated mitophagy: An emerging therapeutic target in acute kidney injury11
Ancestry affects the transcription of small mitochondrial RNAs in human lymphocytes11
Differentiation activates mitochondrial OPA1 processing in myoblast cell lines11
Transplantation of astrocyte-derived mitochondria into injured astrocytes has a protective effect following stretch injury11
Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies11
Altered brown adipose tissue mitochondrial function in newborn fragile X syndrome mice11
Aromatic hydrocarbon receptors in mitochondrial biogenesis and function11
Crystallographic modeling of the PNPT1:c.1453A>G variant as a cause of mitochondrial dysfunction and autosomal recessive deafness; expanding the neuroimaging and clinical features11
Role of mitophagy in pulmonary hypertension: Targeting the mechanism and pharmacological intervention11
Longitudinal changes in mitochondrial-associated measures and insulin resistance in youth with perinatally-acquired HIV in the U.S11
Early cardiac mechanics abnormalities in patients with mitochondrial diseases11
Vessel flow void sign and hyperintense vessel sign on FLAIR images distinguish between MELAS and AIS10
Analysis of compound heterozygous and homozygous mutations found in peripheral subunits of human respiratory Complex I, NDUFS1, NDUFS2, NDUFS8 and NDUFV1, by modeling in the E. coli enzyme10
Identifying the mitochondrial metabolism network by integration of machine learning and explainable artificial intelligence in skeletal muscle in type 2 diabetes10
Intermittent hypoxia preconditioning protects WRL68 cells against oxidative injury: Involvement of the PINK1/Parkin-mediated mitophagy regulated by nuclear respiratory factor 110
Machine learning-based 3D segmentation of mitochondria in polarized epithelial cells10
Laurus nobilis ethanolic extract attenuates hyperglycemia and hyperinsulinemia-induced insulin resistance in HepG2 cell line through the reduction of oxidative stress and improvement of mitochondrial 10
Mitochondria in aging and age-associated diseases9
Temporal changes and control variables of growth differentiation factor 15 levels during the first week of life in hospitalised newborn infants9
Sirtuin 3 and mitochondrial permeability transition pore (mPTP): A systematic review9
HIV-1 gp120 protein promotes HAND through the calcineurin pathway activation9
PKD regulates mitophagy to prevent oxidative stress and mitochondrial dysfunction during mouse oocyte maturation9
Recent trends of natural based therapeutics for mitochondria targeting in Alzheimer’s disease9
The constraints of allotopic expression9
Mitochondrial tRNA variants in 811 Chinese probands with Leber’s hereditary optic neuropathy9
Development of Leigh syndrome with a high probability of cardiac manifestations in infantile-onset patients with m.14453G > A9
Associations of mitochondrial genomic variation with successful neurological aging9
DDQ anti-aging properties expressed with improved mitophagy in mutant tau HT22 neuronal cells9
MitoQuicLy: A high-throughput method for quantifying cell-free DNA from human plasma, serum, and saliva9
The impact of TK2 deficiency syndrome and its treatment by nucleoside therapy on quality of life8
SIRT6 suppresses colon cancer growth by inducing apoptosis and autophagy through transcriptionally down-regulating Survivin8
Mitochondrial bioenergetics and cytometric characterization of a synaptosomal preparation from mouse brain cortex8
Mitochondrial and metabolic features of salugenesis and the healing cycle8
Clinical heterogeneity in patients with m.4412G > A MT-TM mutation and different heteroplasmy levels8
Deciphering the role of MitomiRs in cancer: A comprehensive review8
Yoga improves mitochondrial health and reduces severity of autoimmune inflammatory arthritis: A randomized controlled trial8
The maternal genetic origin and diversity of the extant populations of the Ladakh region in India8
Mitochondrial DNA haplogroups J and T increase the risk of glioma8
Placental mitochondrial DNA mutational load and perinatal outcomes: Findings from a multi-ethnic pregnancy cohort8
β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence8
Diagnosis of primary mitochondrial disorders -Emphasis on myopathological aspects8
Mitochondrial dynamics and mitochondrial autophagy: Molecular structure, orchestrating mechanism and related disorders8
Hemispheric analysis of mitochondrial Complex I and II activity in the mouse model of ischemia-reperfusion-induced injury8
Mitochondrial mechanisms in Treg cell regulation: Implications for immunotherapy and disease treatment8
Global view of dynamic expression and precise mapping of mitochondrial tRNAs-derived fragments during stressed conditions in S. pombe8
Decoding mitochondrial quality control mechanisms: Identifying treatment targets for enhanced cellular health8
Altered insulin pathway compromises mitochondrial function and quality control both in in vitro and in vivo model systems7
Editorial Board7
Clinical and genetic spectrum of mitochondrial DNA depletion syndromes: A report of 6 cases with 4 novel variants7
GenEye24: Novel rapid screening test for the top-3 Leber’s Hereditary Optic Neuropathy pathogenic sequence variants7
Understanding the molecular basis of anti-fibrotic potential of intranasal curcumin and its association with mitochondrial homeostasis in silica-exposed mice7
Assessment of mitochondrial DNA copy number variation relative to nuclear DNA quantity between different tissues7
Corrigendum to “Decreased membrane cholesterol in liver mitochondria of the point mutation mouse model of juvenile Niemann-Pick C1, Npc1” [Mitochondrion 51 (2019) 15–21]7
Mitochondrial DNA mutation pathogenicity score and neurocognitive performance in persons with HIV7
Presence and transmission of mitochondrial heteroplasmic mutations in human populations of European and African ancestry7
Role of mitochondrial potassium channels in ageing7
The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches7
Mitochondria determine response to anti-programmed cell death protein-1 (anti-PD-1) immunotherapy: An evidence-based hypothesis7
Editorial Board7
Large-scale screens identify a 19-Gene MitoScore for improved risk assessment in acute myeloid leukemia7
The mitochondrial chaperone TRAP-1 regulates the glutamine metabolism in tumor cells7
Mitochondrial Mechanisms in Temozolomide Resistance: Unraveling the Complex Interplay and Therapeutic Strategies in Glioblastoma7
Role of Rmd9p in 3′-end processing of mitochondrial 15S rRNA in Saccharomyces cerevisiae7
Extracellular vesicles as carriers for mitochondria: Biological functions and clinical applications7
Telomere length determines the mitochondrial copy number in blastocyst-stage embryos6
The differences in mitochondrial function, mitochondrial dynamics, and cell death between odontogenic cysts/tumors and normal dental follicles6
Actin-related protein 4: An unconventional negative regulator of mitochondrial calcium in protozoan parasite Leishmania6
ER stress-associated transcription factor CREB3 is essential for normal Ca2+, ATP, and ROS homeostasis6
Positive regulation of endothelial Tom70 by metformin as a new mechanism against cardiac microvascular injury in diabetes6
Blood biomarkers for assessment of mitochondrial dysfunction: An expert review6
Interactions between nuclear and mitochondrial SNPs and Parkinson’s disease risk6
In vitro models of insulin resistance: Mitochondrial coupling is differently affected in liver and muscle cells6
Mitochondrial dysfunction in diabetic neuropathy: Impaired mitophagy triggers NLRP3 inflammasome6
Interplay of mitochondria-associated membrane proteins and autophagy: Implications in neurodegeneration6
Neuroprotective effect of autologous mitochondrial transplantation against global ischemia/reperfusion injury in a rat model of cardiac arrest6
Different platforms for mitomiRs in mitochondria: Emerging facets in regulation of mitochondrial functions6
Relationships of mitochondrial DNA mutations and select clinical diagnoses in perinatally HIV- and ART-exposed uninfected children6
Mitochondrial DNA abundance and circulating metabolomic profiling: Multivariable-adjusted and Mendelian randomization analyses in UK Biobank6
Erodible thermogelling hydrogels for localized mitochondrial transplantation to the spinal cord6
Simulated microgravity triggers DNA damage and mitochondria-mediated apoptosis through ROS generation in human promyelocytic leukemic cells6
Regulation of mitochondrial network homeostasis by O-GlcNAcylation6
Endurance swimming exacerbates mitochondrial myopathy in mice with high mtDNA deletions6
A hitchhiker’s guide to mitochondrial quantification5
Editorial Board5
Iron chelation mitigates mitochondrial dysfunction and oxidative stress by enhancing nrf2-mediated antioxidant responses in the renal cortex of a murine model of type 2 diabetes5
ATPAF1 deficiency impairs ATP synthase assembly and mitochondrial respiration5
Mitochondrial dynamics related neurovascular approaches in cerebral ischemic injury5
The Schizosaccharomyces pombe DEAD-box protein Mss116 is required for mitoribosome assembly and mitochondrial translation5
mitoPADdb: A database of mitochondrial proteins associated with diseases5
Revolutionizing cellular energy: The convergence of mitochondrial dynamics and delivery technologies5
Mitochondrial DNA haplogroup, genetic ancestry, and susceptibility to Ewing sarcoma5
A genome-wide association study in human lymphoblastoid cells supports safety of mitochondrial complex I inhibitor5
Energy Metabolism Focused Analysis of Sexual Dimorphism in Biological Aging and Hypothesized Sex-specificity in Sirtuin Dependency5
A novel, conserved and possibly functional motif “WHWGHTW” in mitochondrial transcription across Bilateria5
AutomAted RepeaT Identifier (AARTI): A tool to identify common, polymorphic, and unique microsatellites5
Ancient mitogenomes suggest complex maternal history of one of the oldest settlements of western India5
Mitochondrial iron-sulfur cluster biogenesis and neurological disorders5
The m.3890G>A/MT-ND1 mtDNA rare pathogenic variant: Expanding clinical and MRI phenotypes5
Image-based quantification of mitochondrial iron uptake via Mitoferrin-25
NUDT6 and NUDT9, two mitochondrial members of the NUDIX family, have distinct hydrolysis activities5
Melatonin protects against excessive autophagy-induced mitochondrial and ovarian reserve function deficiency though ERK signaling pathway in Chinese hamster ovary (CHO) cells4
SDHAF2 facilitates mitochondrial respiration through stabilizing succinate dehydrogenase and cytochrome c oxidase assemblies4
Corrigendum to “Laurus nobilis ethanolic extract attenuates hyperglycemia and hyperinsulinemia-induced insulin resistance in HepG2 cell line through the reduction of oxidative stress and improvement o4
Editorial Board4
Genes from oxidative phosphorylation complexes II-V and two dual-function subunits of complex I are transcribed in Viscum album despite absence of the entire mitochondrial holo-complex I4
Plant mitochondria import DNA via alternative membrane complexes involving various VDAC isoforms4
Understanding the neuronal synapse and challenges associated with the mitochondrial dysfunction in mild cognitive impairment and Alzheimer’s disease4
A comprehensive perspective of Huntington’s disease and mitochondrial dysfunction4
MicroRNA-338 inhibition protects against focal cerebral ischemia and preserves mitochondrial function in vitro in astrocytes and neurons via COX4I14
Simultaneous extraction and quantification of circulating mitochondrial and nuclear DNA using a single plasma sample to predict specific molecular diagnostic implications4
Cyt b gene as a valid molecular authentication marker of cow leathers4
Elevated mitochondrial DNA copy number found in ubiquinone-deficient clk-1 mutants is not rescued by ubiquinone precursor 2-4-dihydroxybenzoate4
Complete mitochondrial DNA profile in stroke: A geographical matched case-control study in Spanish population4
Mitochondrial dysfunction and traffic jams in amyotrophic lateral sclerosis4
Mitochondrial bioenergetics in leukocytes and oxidative stress in blood serum of mild to moderately depressed women4
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