Mitochondrion

Article	Citations
The multifaceted modulation of mitochondrial metabolism in tumorigenesis	146
The tissue-specific nature of physiological zebrafish mitochondrial bioenergetics	73
CMT2A-linked MFN2 mutation, T206I promotes mitochondrial hyperfusion and predisposes cells towards mitophagy	68
Sequencing errors in Native American mitogenomes: Impact on clade definitions, haplogroup assignation, and beyond	60
The role of mtDNA haplogroups on metabolic features in narcolepsy type 1	58
Activation of multifunctional DNA repair APE1/Ref-1 enzyme by the dietary phytochemical Ferulic acid protects human neuroblastoma SH-SY5Y cells against Aβ(25–35)-induced oxidative stress and inflammat	52
Delivery of mitoceuticals or respiratory competent mitochondria to sites of neurotrauma	50
What can we do to optimize mitochondrial transplantation therapy for myocardial ischemia–reperfusion injury?	48
Editorial Board	43
Mitofusin 2: The missing link between mtDNA maintenance defects and neurotransmitter disorders	43
A Tunisian POLG mutation expands the clinical spectrum of POLG-related disorders	39
ACAD9 treatment with bezafibrate and nicotinamide riboside temporarily stabilizes cardiomyopathy and lactic acidosis	39
The role of mitochondrial genes in ischemia-reperfusion injury: A systematic review of experimental studies	38
Thyroid hormone enhances efficacy of cisplatin in lung cancer patients via down-regulating GLUT1 expression and reversing the Warburg effect	37
PKM2 is a key regulator of cardiac lipid metabolism in mice	36
Editorial Board	36
Reanalysis of mtDNA mutations of human primordial germ cells (PGCs) reveals NUMT contamination and suggests that selection in PGCs may be positive	34
Role of GM-CSF in regulating metabolism and mitochondrial functions critical to macrophage proliferation	33
The war against Alzheimer, the mitochondrion strikes back!	31
Targeting the redox imbalance in mitochondria: A novel mode for cancer therapy	30
Paternal aging impacts mitochondrial DNA content and telomere length in mouse embryos	30
Editorial Board	30
Mitochondrial density in skeletal and cardiac muscle	30
Mrs2-mediated mitochondrial magnesium uptake is essential for the regulation of MCU-mediated mitochondrial Ca2+ uptake and viability	28
PhNR and peripapillary RNFL changes in Leber hereditary optic neuropathy with m.G11778A mutation	28

Mitochondria in biology and medicine – 2023	26
Pyridoxal-5-phosphate mitigates age-related metabolic imbalances in the rat heart through the H2S/AKT/GSK3β signaling axis	26
Mitophagy in depression: Pathophysiology and treatment targets	26
Reactive oxygen species favors Varicellovirus bovinealpha 5 (BoAHV-5) replication in neural cells	25
Muscle-UCP3 in the regulation of energy metabolism	25
Mitochondrial genome-derived circRNAs: Orphan epigenetic regulators in molecular biology	24
Genomic and non-genomic action of vitamin D on ion channels – Targeting mitochondria	24
Editorial Board	23
Site-specific mitochondrial dysfunction in neurodegeneration	23
Identification of a novel m.3955G > A variant in MT-ND1 associated with Leigh syndrome	22
TRPV4 acts as a mitochondrial Ca2+-importer and regulates mitochondrial temperature and metabolism	22
Decoding the nature and complexity of extracellular mtDNA: Types and implications for health and disease	22
COVID-19 induced liver injury from a new perspective: Mitochondria	21
Reviewing the mitochondrial dysfunction paradigm in rodent models as platforms for neuropsychiatric disease research	21
Blood cell respiration rates and mtDNA copy number: A promising tool for the diagnosis of mitochondrial disease	21
Mitochondrial Irc3 helicase of the thermotolerant yeast Ogataea polymorpha displays dual DNA- and RNA-stimulated ATPase activity	20
Exploring the role of mitochondria transfer/transplant and their long-non-coding RNAs in regenerative therapies for skin aging	19
Mitochondrial transplantation therapy inhibits the proliferation of malignant hepatocellular carcinoma and its mechanism	19
Impact of missense mutations on the structure–function relationship of human succinyl-CoA synthetase using in silico analysis	19
The maternal genetic history of tribal populations of Chhattisgarh, India	18
Association analysis of mitochondrial DNA heteroplasmic variants: Methods and application	18
Targeted mitochondrial metabolism for anti-tumor therapy	17
Mitochondrial oxidative stress in brain microvascular endothelial cells: Triggering blood-brain barrier disruption	17
Newer mitochondrial dynamics and their role of calcium signalling in liver regeneration	17
Understanding differential aspects of microdiffusion (channeling) in the Coenzyme Q and Cytochrome c regions of the mitochondrial respiratory system	17
Urolithin-A supplementation alleviates sepsis-induced acute lung injury by reducing mitochondrial dysfunction and modulating macrophage polarization	17
Advancing mitochondria as a therapeutic agent	16
Serum TCA cycle metabolites in Lewy bodies dementia and Alzheimer's disease: Network analysis and cognitive prognosis	16
Interplay of mitochondria and diabetes: Unveiling novel therapeutic strategies	16
2-Aminoethoxydiphenyl borate ameliorates mitochondrial dysfunctions in MPTP/MPP+ model of Parkinson’s disease	16
Mitochondria dysfunction and impaired response to oxidative stress promotes proteostasis disruption in aged human cells	16
Kinetic characterization of respirasomes and free complex I from Yarrowia lipolytica	15
Mitochondrial dysfunction and inflammasome activation in neurodegenerative diseases: Mechanisms and therapeutic implications	15
An integrated multi-omics approach allowed ultra-rapid diagnosis of a deep intronic pathogenic variant in PDHX and precision treatment in a neonate critically ill with lactic acidosis	15
Corrigendum to “Comparison of whole genome sequencing and targeted sequencing for mitochondrial DNA” [Mitochondrion 58 (2021) 303–310]	15
Mitochondrial quality control in exercise-mitigated muscular atrophy	15
Mitochondrial bioenergetics of breast cancer	14
Novel mutations in MTERF3: First report of a new genetic cause in two Chinese patients with developmental delay, intermittent hypoglycemia and metabolic acidosis	14
Application research of novel peptide mitochondrial-targeted antioxidant SS-31 in mitigating mitochondrial dysfunction	14
Neuroprotective compounds alter the expression of genes coding for proteins related to mitochondrial function in activated microglia	14
The biology of mitochondrial carrier homolog 2	14
Research progress on paternal mitochondrial inheritance: An overview	13
Visualization of mitophagy using LysoKK, a 7-nitro-2,1,3-benzoxadiazole-(arylpropyl)benzylamine derivative	13
Fighting Parkinson’s disease: The return of the mitochondria	13
Targeting the mitochondria in chronic respiratory diseases	13
Targeting mitochondria with small molecules: A promising strategy for combating Parkinson’s disease	13
Whole genome sequencing followed by functional analysis of genomic deletion encompassing ERCC8 and NDUFAF2 genes in a non-consanguineous Indian family reveals dysfunctional mitochondrial bioenergetics	13
The Parkinson’s disease-associated mutation LRRK2 G2385R alters mitochondrial biogenesis via the PGC-1α-TFAM pathway	13
Prognostic value of circulating mitochondrial DNA in prostate cancer and underlying mechanism	13
RTN3 deficiency exacerbates cisplatin-induced acute kidney injury through the disruption of mitochondrial stability	13

Selective and reversible disruption of mitochondrial inner membrane protein complexes by lipophilic cations	13
Defining ER-mitochondria contact dynamics in Plasmodium falciparum by targeting component of phospholipid synthesis pathway, phosphatidylserine synthase (PfPSS)	13
Miro1 improves the exogenous engraftment efficiency and therapeutic potential of mitochondria transfer using Wharton's jelly mesenchymal stem cells	13
Ancestry affects the transcription of small mitochondrial RNAs in human lymphocytes	12
Altered brown adipose tissue mitochondrial function in newborn fragile X syndrome mice	12
Cancer/Testis Antigen 55 is required for cancer cell proliferation and mitochondrial DNA maintenance	12
Longitudinal changes in mitochondrial-associated measures and insulin resistance in youth with perinatally-acquired HIV in the U.S	12
Role of mitophagy in pulmonary hypertension: Targeting the mechanism and pharmacological intervention	12
Receptor-mediated mitophagy: An emerging therapeutic target in acute kidney injury	12
Severe acute respiratory syndrome coronaviruses contributing to mitochondrial dysfunction: Implications for post-COVID complications	12
Editorial Board	12
Aromatic hydrocarbon receptors in mitochondrial biogenesis and function	12
Differentiation activates mitochondrial OPA1 processing in myoblast cell lines	11
Type 1 diabetes mellitus: Inflammation, mitophagy, and mitochondrial function	11
Editorial Board	11
Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies	11
WITHDRAWN: Mitochondrial oxygen respiration is associated with loneliness in a sample of community-dwelling adults	11
Perceived association of mood and symptom severity in adults with mitochondrial diseases	11
Early cardiac mechanics abnormalities in patients with mitochondrial diseases	10
Identifying the mitochondrial metabolism network by integration of machine learning and explainable artificial intelligence in skeletal muscle in type 2 diabetes	10
The constraints of allotopic expression	10
Temporal changes and control variables of growth differentiation factor 15 levels during the first week of life in hospitalised newborn infants	10
Auditory neuropathy spectrum disorder and related auditory features in patients with hearing loss associated with the MT-TS1 m.7471dup variant	10
Mitochondria in aging and age-associated diseases	10
Analysis of compound heterozygous and homozygous mutations found in peripheral subunits of human respiratory Complex I, NDUFS1, NDUFS2, NDUFS8 and NDUFV1, by modeling in the E. coli enzyme	10
MitoQuicLy: A high-throughput method for quantifying cell-free DNA from human plasma, serum, and saliva	10
Miro1- a key player in β-cell function and mitochondrial dynamics under diabetes mellitus	10
Machine learning-based 3D segmentation of mitochondria in polarized epithelial cells	10
Sirtuin 3 and mitochondrial permeability transition pore (mPTP): A systematic review	10
DDQ anti-aging properties expressed with improved mitophagy in mutant tau HT22 neuronal cells	10
Transplantation of astrocyte-derived mitochondria into injured astrocytes has a protective effect following stretch injury	10
HIV-1 gp120 protein promotes HAND through the calcineurin pathway activation	9
Mitochondrial dynamics and mitochondrial autophagy: Molecular structure, orchestrating mechanism and related disorders	9
Mitochondrial mechanisms in Treg cell regulation: Implications for immunotherapy and disease treatment	9
The impact of TK2 deficiency syndrome and its treatment by nucleoside therapy on quality of life	9
Associations of mitochondrial genomic variation with successful neurological aging	9
Recent trends of natural based therapeutics for mitochondria targeting in Alzheimer’s disease	9
Development of Leigh syndrome with a high probability of cardiac manifestations in infantile-onset patients with m.14453G > A	9
Mitochondrial tRNA variants in 811 Chinese probands with Leber’s hereditary optic neuropathy	9
PKD regulates mitophagy to prevent oxidative stress and mitochondrial dysfunction during mouse oocyte maturation	9
Hemispheric analysis of mitochondrial Complex I and II activity in the mouse model of ischemia-reperfusion-induced injury	8
Mitochondrial bioenergetics and cytometric characterization of a synaptosomal preparation from mouse brain cortex	8
Diagnosis of primary mitochondrial disorders -Emphasis on myopathological aspects	8
β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence	8
SIRT6 suppresses colon cancer growth by inducing apoptosis and autophagy through transcriptionally down-regulating Survivin	8
The maternal genetic origin and diversity of the extant populations of the Ladakh region in India	8
Deciphering the role of MitomiRs in cancer: A comprehensive review	8
Decoding mitochondrial quality control mechanisms: Identifying treatment targets for enhanced cellular health	8
The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches	7
Extracellular vesicles as carriers for mitochondria: Biological functions and clinical applications	7
GenEye24: Novel rapid screening test for the top-3 Leber’s Hereditary Optic Neuropathy pathogenic sequence variants	7
Assessment of mitochondrial DNA copy number variation relative to nuclear DNA quantity between different tissues	7
Mitochondrial Mechanisms in Temozolomide Resistance: Unraveling the Complex Interplay and Therapeutic Strategies in Glioblastoma	7
Understanding the molecular basis of anti-fibrotic potential of intranasal curcumin and its association with mitochondrial homeostasis in silica-exposed mice	7
Role of mitochondrial potassium channels in ageing	7
Mitochondrial DNA abundance and circulating metabolomic profiling: Multivariable-adjusted and Mendelian randomization analyses in UK Biobank	7
Mitochondria determine response to anti-programmed cell death protein-1 (anti-PD-1) immunotherapy: An evidence-based hypothesis	7
Mitochondrial and metabolic features of salugenesis and the healing cycle	7
Role of Rmd9p in 3′-end processing of mitochondrial 15S rRNA in Saccharomyces cerevisiae	7
Machine learning to predict mitochondrial diseases by phenotypes	7
Relationships of mitochondrial DNA mutations and select clinical diagnoses in perinatally HIV- and ART-exposed uninfected children	7
In vitro models of insulin resistance: Mitochondrial coupling is differently affected in liver and muscle cells	6
Beneficial effects of mitophagy enhancers on amyloid beta-induced mitochondrial and synaptic toxicities in Alzheimer’s disease	6
The mitochondrial chaperone TRAP-1 regulates the glutamine metabolism in tumor cells	6
Mitochondrial DNA mutation pathogenicity score and neurocognitive performance in persons with HIV	6
Blood biomarkers for assessment of mitochondrial dysfunction: An expert review	6
Actin-related protein 4: An unconventional negative regulator of mitochondrial calcium in protozoan parasite Leishmania	6
Interactions between nuclear and mitochondrial SNPs and Parkinson’s disease risk	6
Telomere length determines the mitochondrial copy number in blastocyst-stage embryos	6
Different platforms for mitomiRs in mitochondria: Emerging facets in regulation of mitochondrial functions	6
Corrigendum to “Decreased membrane cholesterol in liver mitochondria of the point mutation mouse model of juvenile Niemann-Pick C1, Npc1” [Mitochondrion 51 (2019) 15–21]	6
Erodible thermogelling hydrogels for localized mitochondrial transplantation to the spinal cord	6
Clinical and genetic spectrum of mitochondrial DNA depletion syndromes: A report of 6 cases with 4 novel variants	6
Large-scale screens identify a 19-Gene MitoScore for improved risk assessment in acute myeloid leukemia	6
Endurance swimming exacerbates mitochondrial myopathy in mice with high mtDNA deletions	6
Editorial Board	6
Interplay of mitochondria-associated membrane proteins and autophagy: Implications in neurodegeneration	6
ER stress-associated transcription factor CREB3 is essential for normal Ca2+, ATP, and ROS homeostasis	6
AutomAted RepeaT Identifier (AARTI): A tool to identify common, polymorphic, and unique microsatellites	5
The Schizosaccharomyces pombe DEAD-box protein Mss116 is required for mitoribosome assembly and mitochondrial translation	5

A novel, conserved and possibly functional motif “WHWGHTW” in mitochondrial transcription across Bilateria	5
Editorial Board	5
Mitochondrial dynamics related neurovascular approaches in cerebral ischemic injury	5
NUDT6 and NUDT9, two mitochondrial members of the NUDIX family, have distinct hydrolysis activities	5
Regulation of mitochondrial network homeostasis by O-GlcNAcylation	5
Mitochondrial dysfunction in diabetic neuropathy: Impaired mitophagy triggers NLRP3 inflammasome	5
Image-based quantification of mitochondrial iron uptake via Mitoferrin-2	5
Mitochondrial transplantation: Triumphs, challenges, and impacts on nuclear genome remodelling	5
Ultrastructural and functional recovery of mitochondria and improved developmental competence by melatonin in oxidatively stressed porcine oocytes	5
Ancient mitogenomes suggest complex maternal history of one of the oldest settlements of western India	5
Iron chelation mitigates mitochondrial dysfunction and oxidative stress by enhancing nrf2-mediated antioxidant responses in the renal cortex of a murine model of type 2 diabetes	5
mitoPADdb: A database of mitochondrial proteins associated with diseases	5
Positive regulation of endothelial Tom70 by metformin as a new mechanism against cardiac microvascular injury in diabetes	5
Revolutionizing cellular energy: The convergence of mitochondrial dynamics and delivery technologies	5
Simulated microgravity triggers DNA damage and mitochondria-mediated apoptosis through ROS generation in human promyelocytic leukemic cells	5
Neuroprotective effect of autologous mitochondrial transplantation against global ischemia/reperfusion injury in a rat model of cardiac arrest	5
Krebs cycle derivatives, dimethyl fumarate and itaconate, control metabolic reprogramming in inflammatory human microglia cell line	4
Partial inhibition of mitochondrial-linked pyrimidine synthesis increases tumorigenic potential and lysosome accumulation	4
Understanding the neuronal synapse and challenges associated with the mitochondrial dysfunction in mild cognitive impairment and Alzheimer’s disease	4
A comprehensive perspective of Huntington’s disease and mitochondrial dysfunction	4
Cyt b gene as a valid molecular authentication marker of cow leathers	4
Genes from oxidative phosphorylation complexes II-V and two dual-function subunits of complex I are transcribed in Viscum album despite absence of the entire mitochondrial holo-complex I	4
Simultaneous extraction and quantification of circulating mitochondrial and nuclear DNA using a single plasma sample to predict specific molecular diagnostic implications	4
Transplanting mitochondria from gastric epithelial cells reduces the malignancy of gastric cancer	4
Editorial Board	4
Melatonin protects against excessive autophagy-induced mitochondrial and ovarian reserve function deficiency though ERK signaling pathway in Chinese hamster ovary (CHO) cells	4
Editorial Board	4
Mitochondrial iron-sulfur cluster biogenesis and neurological disorders	4
Complete mitochondrial DNA profile in stroke: A geographical matched case-control study in Spanish population	4
Editorial Board	4
Outlier maternal haplogroups N5 and X2 and their potential role in elevated tuberculosis prevalence among the Sahariya tribe	4
Augmented Parkin-dependent mitophagy underlies the hepatoprotective effect of remote ischemic conditioning used prior to hemorrhagic shock	4
Mitochondrial DNA haplogroup, genetic ancestry, and susceptibility to Ewing sarcoma	4
SDHAF2 facilitates mitochondrial respiration through stabilizing succinate dehydrogenase and cytochrome c oxidase assemblies	4
Corrigendum to “Laurus nobilis ethanolic extract attenuates hyperglycemia and hyperinsulinemia-induced insulin resistance in HepG2 cell line through the reduction of oxidative stress and improvement o	4