Mitochondrion

Article	Citations
Sequencing errors in Native American mitogenomes: Impact on clade definitions, haplogroup assignation, and beyond	244
The tissue-specific nature of physiological zebrafish mitochondrial bioenergetics	111
CMT2A-linked MFN2 mutation, T206I promotes mitochondrial hyperfusion and predisposes cells towards mitophagy	75
The multifaceted modulation of mitochondrial metabolism in tumorigenesis	64
Editorial Board	63
Delivery of mitoceuticals or respiratory competent mitochondria to sites of neurotrauma	62
A Tunisian POLG mutation expands the clinical spectrum of POLG-related disorders	51
What can we do to optimize mitochondrial transplantation therapy for myocardial ischemia–reperfusion injury?	49
ACAD9 treatment with bezafibrate and nicotinamide riboside temporarily stabilizes cardiomyopathy and lactic acidosis	43
Activation of multifunctional DNA repair APE1/Ref-1 enzyme by the dietary phytochemical Ferulic acid protects human neuroblastoma SH-SY5Y cells against Aβ(25–35)-induced oxidative stress and inflammat	42
Mrs2-mediated mitochondrial magnesium uptake is essential for the regulation of MCU-mediated mitochondrial Ca2+ uptake and viability	39
Mitochondria in biology and medicine – 2023	39
The role of mitochondrial genes in ischemia-reperfusion injury: A systematic review of experimental studies	39
Editorial Board	36
Thyroid hormone enhances efficacy of cisplatin in lung cancer patients via down-regulating GLUT1 expression and reversing the Warburg effect	36
Reanalysis of mtDNA mutations of human primordial germ cells (PGCs) reveals NUMT contamination and suggests that selection in PGCs may be positive	35
PhNR and peripapillary RNFL changes in Leber hereditary optic neuropathy with m.G11778A mutation	35
PKM2 is a key regulator of cardiac lipid metabolism in mice	34
Mitochondrial density in skeletal and cardiac muscle	33
Paternal aging impacts mitochondrial DNA content and telomere length in mouse embryos	31
Reactive oxygen species favors Varicellovirus bovinealpha 5 (BoAHV-5) replication in neural cells	29
Editorial Board	28
Pyridoxal-5-phosphate mitigates age-related metabolic imbalances in the rat heart through the H2S/AKT/GSK3β signaling axis	28
Mitochondrial genome-derived circRNAs: Orphan epigenetic regulators in molecular biology	28
Muscle-UCP3 in the regulation of energy metabolism	27

The evolving landscape of mitochondrial base editing: advances in precision, modeling, and therapeutic potential	26
Genomic and non-genomic action of vitamin D on ion channels – Targeting mitochondria	26
TRPV4 acts as a mitochondrial Ca2+-importer and regulates mitochondrial temperature and metabolism	25
COVID-19 induced liver injury from a new perspective: Mitochondria	25
COXFA4L3 enhances mitochondrial complex IV function to boost ATP synthesis and drive sperm motility	25
Mitochondrial Irc3 helicase of the thermotolerant yeast Ogataea polymorpha displays dual DNA- and RNA-stimulated ATPase activity	25
Intravenous mitochondrial transplantation as an adjunctive therapy for dilated cardiomyopathy	24
Mitochondrial DNA analysis in a cohort of stillbirths with brainstem and cardiac conduction system abnormalities	23
Decoding the nature and complexity of extracellular mtDNA: Types and implications for health and disease	23
The maternal genetic history of tribal populations of Chhattisgarh, India	23
Exploring the role of mitochondria transfer/transplant and their long-non-coding RNAs in regenerative therapies for skin aging	23
Impact of missense mutations on the structure–function relationship of human succinyl-CoA synthetase using in silico analysis	23
Advancing mitochondria as a therapeutic agent	22
Association analysis of mitochondrial DNA heteroplasmic variants: Methods and application	22
Serum TCA cycle metabolites in Lewy bodies dementia and Alzheimer's disease: Network analysis and cognitive prognosis	22
2-Aminoethoxydiphenyl borate ameliorates mitochondrial dysfunctions in MPTP/MPP+ model of Parkinson’s disease	22
Editorial Board	21
Unmasking NLRX1: Exploring the broadening biological landscape of a mysterious mitochondrial sensor	21
Targeted mitochondrial metabolism for anti-tumor therapy	20
Mitochondria dysfunction and impaired response to oxidative stress promotes proteostasis disruption in aged human cells	20
Understanding differential aspects of microdiffusion (channeling) in the Coenzyme Q and Cytochrome c regions of the mitochondrial respiratory system	20
Newer mitochondrial dynamics and their role of calcium signalling in liver regeneration	20
Mitochondrial oxidative stress in brain microvascular endothelial cells: Triggering blood-brain barrier disruption	19
Kinetic characterization of respirasomes and free complex I from Yarrowia lipolytica	18
Interplay of mitochondria and diabetes: Unveiling novel therapeutic strategies	18
Urolithin-A supplementation alleviates sepsis-induced acute lung injury by reducing mitochondrial dysfunction and modulating macrophage polarization	18
An integrated multi-omics approach allowed ultra-rapid diagnosis of a deep intronic pathogenic variant in PDHX and precision treatment in a neonate critically ill with lactic acidosis	16
Mitochondrial quality control in exercise-mitigated muscular atrophy	16
Application research of novel peptide mitochondrial-targeted antioxidant SS-31 in mitigating mitochondrial dysfunction	16
Mitochondrial Transcription: A click-chemistry derived detection methodology forgoing the use of radiation in in vitro analyses	16
Mitochondrial dysfunction and inflammasome activation in neurodegenerative diseases: Mechanisms and therapeutic implications	16
The biology of mitochondrial carrier homolog 2	16
Whole genome sequencing followed by functional analysis of genomic deletion encompassing ERCC8 and NDUFAF2 genes in a non-consanguineous Indian family reveals dysfunctional mitochondrial bioenergetics	15
Prognostic value of circulating mitochondrial DNA in prostate cancer and underlying mechanism	15
Neuroprotective compounds alter the expression of genes coding for proteins related to mitochondrial function in activated microglia	15
Mitochondrial dysfunction–induced PANoptosis: Mechanisms, triggers, and disease implications	15
Novel mutations in MTERF3: First report of a new genetic cause in two Chinese patients with developmental delay, intermittent hypoglycemia and metabolic acidosis	15
Quantitative imaging of mitochondrial redox conditions at the single-organelle level	15
Mitochondrial bioenergetics of breast cancer	15
Research progress on paternal mitochondrial inheritance: An overview	14
Targeting mitochondria with small molecules: A promising strategy for combating Parkinson’s disease	14
The Parkinson’s disease-associated mutation LRRK2 G2385R alters mitochondrial biogenesis via the PGC-1α-TFAM pathway	14
Selective and reversible disruption of mitochondrial inner membrane protein complexes by lipophilic cations	14
RTN3 deficiency exacerbates cisplatin-induced acute kidney injury through the disruption of mitochondrial stability	14
Longitudinal changes in mitochondrial-associated measures and insulin resistance in youth with perinatally-acquired HIV in the U.S	14
Targeting the mitochondria in chronic respiratory diseases	14
Miro1 improves the exogenous engraftment efficiency and therapeutic potential of mitochondria transfer using Wharton's jelly mesenchymal stem cells	14
Role of mitophagy in pulmonary hypertension: Targeting the mechanism and pharmacological intervention	13
Differentiation activates mitochondrial OPA1 processing in myoblast cell lines	13
Severe acute respiratory syndrome coronaviruses contributing to mitochondrial dysfunction: Implications for post-COVID complications	13

Ancestry affects the transcription of small mitochondrial RNAs in human lymphocytes	13
Serum cell-free mitochondrial DNA under a highly standardized and controlled stress induction	13
WITHDRAWN: Mitochondrial oxygen respiration is associated with loneliness in a sample of community-dwelling adults	13
Type 1 diabetes mellitus: Inflammation, mitophagy, and mitochondrial function	12
URMD-Seq: A high-throughput method for scalable detection of ultra-rare mutations in the human mitochondrial genome	12
Editorial Board	12
Integrated exome and mitochondrial genome sequencing reveals the genetic landscape of primary mitochondrial diseases: findings from a large Tunisian cohort	12
Receptor-mediated mitophagy: An emerging therapeutic target in acute kidney injury	12
Perceived association of mood and symptom severity in adults with mitochondrial diseases	12
Auditory neuropathy spectrum disorder and related auditory features in patients with hearing loss associated with the MT-TS1 m.7471dup variant	12
Early cardiac mechanics abnormalities in patients with mitochondrial diseases	11
Mitochondria in aging and age-associated diseases	11
Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies	11
Machine learning-based 3D segmentation of mitochondria in polarized epithelial cells	11
MitoQuicLy: A high-throughput method for quantifying cell-free DNA from human plasma, serum, and saliva	11
Analysis of compound heterozygous and homozygous mutations found in peripheral subunits of human respiratory Complex I, NDUFS1, NDUFS2, NDUFS8 and NDUFV1, by modeling in the E. coli enzyme	10
Dysregulated iron homeostasis Drives mitochondrial Injury and ferroptosis susceptibility in MELAS fibroblasts	10
Miro1- a key player in β-cell function and mitochondrial dynamics under diabetes mellitus	10
DDQ anti-aging properties expressed with improved mitophagy in mutant tau HT22 neuronal cells	10
Identifying the mitochondrial metabolism network by integration of machine learning and explainable artificial intelligence in skeletal muscle in type 2 diabetes	10
Transplantation of astrocyte-derived mitochondria into injured astrocytes has a protective effect following stretch injury	10
The constraints of allotopic expression	10
Associations of mitochondrial genomic variation with successful neurological aging	9
Mitochondrial dynamics and mitochondrial autophagy: Molecular structure, orchestrating mechanism and related disorders	9
Mitochondrial mechanisms in Treg cell regulation: Implications for immunotherapy and disease treatment	9
β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence	9
Probability of Mitochondrial DNA heteroplasmy in different tissues from European populations	9
Mitochondrial iron overload is associated with lysosomal dysfunction-mediated mitophagy impairment in the heart of Friedreich’s ataxia	9
HIV-1 gp120 protein promotes HAND through the calcineurin pathway activation	9
Transcriptional activation by MNRR1 is effected by recruiting p300 and can be induced by minimal peptides	9
Mitochondrial bioenergetics and cytometric characterization of a synaptosomal preparation from mouse brain cortex	9
Deciphering the role of MitomiRs in cancer: A comprehensive review	9
PKD regulates mitophagy to prevent oxidative stress and mitochondrial dysfunction during mouse oocyte maturation	9
The impact of TK2 deficiency syndrome and its treatment by nucleoside therapy on quality of life	9
The maternal genetic origin and diversity of the extant populations of the Ladakh region in India	9
SIRT6 suppresses colon cancer growth by inducing apoptosis and autophagy through transcriptionally down-regulating Survivin	9
Editorial Board	9
Role of mitochondrial potassium channels in ageing	8
Hemispheric analysis of mitochondrial Complex I and II activity in the mouse model of ischemia-reperfusion-induced injury	8
Understanding the molecular basis of anti-fibrotic potential of intranasal curcumin and its association with mitochondrial homeostasis in silica-exposed mice	8
GenEye24: Novel rapid screening test for the top-3 Leber’s Hereditary Optic Neuropathy pathogenic sequence variants	8
Mitochondrial DNA abundance and circulating metabolomic profiling: Multivariable-adjusted and Mendelian randomization analyses in UK Biobank	8
Decoding mitochondrial quality control mechanisms: Identifying treatment targets for enhanced cellular health	8
Extracellular vesicles as carriers for mitochondria: Biological functions and clinical applications	8
Machine learning to predict mitochondrial diseases by phenotypes	8
Mitochondrial Mechanisms in Temozolomide Resistance: Unraveling the Complex Interplay and Therapeutic Strategies in Glioblastoma	8
Relationships of mitochondrial DNA mutations and select clinical diagnoses in perinatally HIV- and ART-exposed uninfected children	8
Mitochondrial and metabolic features of salugenesis and the healing cycle	8
The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches	8
Role of Rmd9p in 3′-end processing of mitochondrial 15S rRNA in Saccharomyces cerevisiae	8
Assessment of mitochondrial DNA copy number variation relative to nuclear DNA quantity between different tissues	8
Mitochondrial DNA mutation pathogenicity score and neurocognitive performance in persons with HIV	8
Endurance swimming exacerbates mitochondrial myopathy in mice with high mtDNA deletions	7
Different platforms for mitomiRs in mitochondria: Emerging facets in regulation of mitochondrial functions	7
Patient-derived TWNK variants recapitulate multisystem Perrault syndrome pathology in a mouse model	7
Beneficial effects of mitophagy enhancers on amyloid beta-induced mitochondrial and synaptic toxicities in Alzheimer’s disease	7
Interplay of mitochondria-associated membrane proteins and autophagy: Implications in neurodegeneration	7
Mitochondria transfer from myocytes to endothelial cells promotes angiogenesis in skeletal muscle	7
Mitochondrial dysfunction in diabetic neuropathy: Impaired mitophagy triggers NLRP3 inflammasome	7
Impact of compound heterozygous SDHA variants on mitochondrial function in pediatric with neurological disease	7
Large-scale screens identify a 19-Gene MitoScore for improved risk assessment in acute myeloid leukemia	7
The mitochondrial chaperone TRAP-1 regulates the glutamine metabolism in tumor cells	7
Telomere length determines the mitochondrial copy number in blastocyst-stage embryos	7
ER stress-associated transcription factor CREB3 is essential for normal Ca2+, ATP, and ROS homeostasis	7
Editorial Board	6
TNF-α-mediated down-regulation of mitochondrial transcription factors: Rescue by Angiotensin-(1–7) peptide	6
Neuroprotective effect of autologous mitochondrial transplantation against global ischemia/reperfusion injury in a rat model of cardiac arrest	6
Ultrastructural and functional recovery of mitochondria and improved developmental competence by melatonin in oxidatively stressed porcine oocytes	6
mitoPADdb: A database of mitochondrial proteins associated with diseases	6
NUDT6 and NUDT9, two mitochondrial members of the NUDIX family, have distinct hydrolysis activities	6
Iron chelation mitigates mitochondrial dysfunction and oxidative stress by enhancing nrf2-mediated antioxidant responses in the renal cortex of a murine model of type 2 diabetes	6
Revolutionizing cellular energy: The convergence of mitochondrial dynamics and delivery technologies	6
The Schizosaccharomyces pombe DEAD-box protein Mss116 is required for mitoribosome assembly and mitochondrial translation	6
The mitochondrial protein TMEM177 fine-tunes mammalian cytochrome c oxidase assembly	6
Image-based quantification of mitochondrial iron uptake via Mitoferrin-2	6
Mitochondrial dynamics related neurovascular approaches in cerebral ischemic injury	5
A 3-hit metabolic signaling model for the core symptoms of autism spectrum disorder	5
SDHAF2 facilitates mitochondrial respiration through stabilizing succinate dehydrogenase and cytochrome c oxidase assemblies	5
Editorial Board	5
Ancient mitogenomes suggest complex maternal history of one of the oldest settlements of western India	5

Overexpression of miR-455-3p enhances mitophagy, synaptic and mitochondrial proteins in Alzheimer’s disease	5
A comprehensive perspective of Huntington’s disease and mitochondrial dysfunction	5
Simultaneous extraction and quantification of circulating mitochondrial and nuclear DNA using a single plasma sample to predict specific molecular diagnostic implications	5
Cyt b gene as a valid molecular authentication marker of cow leathers	5
A novel, conserved and possibly functional motif “WHWGHTW” in mitochondrial transcription across Bilateria	5
Editorial Board	5
Understanding the neuronal synapse and challenges associated with the mitochondrial dysfunction in mild cognitive impairment and Alzheimer’s disease	5
Mitochondrial DNA haplogroup, genetic ancestry, and susceptibility to Ewing sarcoma	5
Mitochondrial transplantation: Triumphs, challenges, and impacts on nuclear genome remodelling	5