Mitochondrion

Papers
(The median citation count of Mitochondrion is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
The role of mtDNA haplogroups on metabolic features in narcolepsy type 1148
The multifaceted modulation of mitochondrial metabolism in tumorigenesis133
Sequencing errors in Native American mitogenomes: Impact on clade definitions, haplogroup assignation, and beyond67
Hsp90 and its mitochondrial homologue TRAP-1 independently regulate hypoxia adaptations in Caenorhabditis elegans63
CMT2A-linked MFN2 mutation, T206I promotes mitochondrial hyperfusion and predisposes cells towards mitophagy60
The tissue-specific nature of physiological zebrafish mitochondrial bioenergetics55
Editorial Board51
Mitofusin 2: The missing link between mtDNA maintenance defects and neurotransmitter disorders44
ACAD9 treatment with bezafibrate and nicotinamide riboside temporarily stabilizes cardiomyopathy and lactic acidosis39
Delivery of mitoceuticals or respiratory competent mitochondria to sites of neurotrauma38
What can we do to optimize mitochondrial transplantation therapy for myocardial ischemia–reperfusion injury?38
Activation of multifunctional DNA repair APE1/Ref-1 enzyme by the dietary phytochemical Ferulic acid protects human neuroblastoma SH-SY5Y cells against Aβ(25–35)-induced oxidative stress and inflammat38
The role of mitochondrial genes in ischemia-reperfusion injury: A systematic review of experimental studies36
Editorial Board35
Thyroid hormone enhances efficacy of cisplatin in lung cancer patients via down-regulating GLUT1 expression and reversing the Warburg effect35
Editorial Board34
Role of GM-CSF in regulating metabolism and mitochondrial functions critical to macrophage proliferation32
Reanalysis of mtDNA mutations of human primordial germ cells (PGCs) reveals NUMT contamination and suggests that selection in PGCs may be positive32
Targeting the redox imbalance in mitochondria: A novel mode for cancer therapy31
PhNR and peripapillary RNFL changes in Leber hereditary optic neuropathy with m.G11778A mutation28
Mitochondria in biology and medicine – 202328
Paternal aging impacts mitochondrial DNA content and telomere length in mouse embryos27
Mitochondrial density in skeletal and cardiac muscle25
Mitophagy in depression: Pathophysiology and treatment targets25
Editorial Board24
The war against Alzheimer, the mitochondrion strikes back!24
Muscle-UCP3 in the regulation of energy metabolism24
Mrs2-mediated mitochondrial magnesium uptake is essential for the regulation of MCU-mediated mitochondrial Ca2+ uptake and viability24
Pyridoxal-5-phosphate mitigates age-related metabolic imbalances in the rat heart through the H2S/AKT/GSK3β signaling axis23
Reactive oxygen species favors Varicellovirus bovinealpha 5 (BoAHV-5) replication in neural cells22
Genomic and non-genomic action of vitamin D on ion channels – Targeting mitochondria22
Identification of a novel m.3955G > A variant in MT-ND1 associated with Leigh syndrome21
Decoding the nature and complexity of extracellular mtDNA: Types and implications for health and disease21
Site-specific mitochondrial dysfunction in neurodegeneration21
Exploring the role of mitochondria transfer/transplant and their long-non-coding RNAs in regenerative therapies for skin aging21
Mitochondrial genome-derived circRNAs: Orphan epigenetic regulators in molecular biology21
Mitochondrial Irc3 helicase of the thermotolerant yeast Ogataea polymorpha displays dual DNA- and RNA-stimulated ATPase activity20
Blood cell respiration rates and mtDNA copy number: A promising tool for the diagnosis of mitochondrial disease20
Reviewing the mitochondrial dysfunction paradigm in rodent models as platforms for neuropsychiatric disease research20
COVID-19 induced liver injury from a new perspective: Mitochondria20
TRPV4 acts as a mitochondrial Ca2+-importer and regulates mitochondrial temperature and metabolism20
Mitochondrial transplantation therapy inhibits the proliferation of malignant hepatocellular carcinoma and its mechanism20
Impact of missense mutations on the structure–function relationship of human succinyl-CoA synthetase using in silico analysis19
Understanding differential aspects of microdiffusion (channeling) in the Coenzyme Q and Cytochrome c regions of the mitochondrial respiratory system19
The maternal genetic history of tribal populations of Chhattisgarh, India19
Association analysis of mitochondrial DNA heteroplasmic variants: Methods and application18
Urolithin-A supplementation alleviates sepsis-induced acute lung injury by reducing mitochondrial dysfunction and modulating macrophage polarization17
Advancing mitochondria as a therapeutic agent17
Mitochondria dysfunction and impaired response to oxidative stress promotes proteostasis disruption in aged human cells16
2-Aminoethoxydiphenyl borate ameliorates mitochondrial dysfunctions in MPTP/MPP+ model of Parkinson’s disease16
Interplay of mitochondria and diabetes: Unveiling novel therapeutic strategies16
Serum TCA cycle metabolites in Lewy bodies dementia and Alzheimer's disease: Network analysis and cognitive prognosis16
An integrated multi-omics approach allowed ultra-rapid diagnosis of a deep intronic pathogenic variant in PDHX and precision treatment in a neonate critically ill with lactic acidosis15
Newer mitochondrial dynamics and their role of calcium signalling in liver regeneration15
Application research of novel peptide mitochondrial-targeted antioxidant SS-31 in mitigating mitochondrial dysfunction15
Mitochondrial oxidative stress in brain microvascular endothelial cells: Triggering blood-brain barrier disruption15
Kinetic characterization of respirasomes and free complex I from Yarrowia lipolytica14
Neuroprotective compounds alter the expression of genes coding for proteins related to mitochondrial function in activated microglia14
Targeting mitochondria with small molecules: A promising strategy for combating Parkinson’s disease14
Whole genome sequencing followed by functional analysis of genomic deletion encompassing ERCC8 and NDUFAF2 genes in a non-consanguineous Indian family reveals dysfunctional mitochondrial bioenergetics14
The biology of mitochondrial carrier homolog 214
Miro1 improves the exogenous engraftment efficiency and therapeutic potential of mitochondria transfer using Wharton's jelly mesenchymal stem cells14
Mitochondrial bioenergetics of breast cancer14
Corrigendum to “Comparison of whole genome sequencing and targeted sequencing for mitochondrial DNA” [Mitochondrion 58 (2021) 303–310]14
Mitochondrial dysfunction and inflammasome activation in neurodegenerative diseases: Mechanisms and therapeutic implications14
Prognostic value of circulating mitochondrial DNA in prostate cancer and underlying mechanism14
Research progress on paternal mitochondrial inheritance: An overview14
Selective and reversible disruption of mitochondrial inner membrane protein complexes by lipophilic cations13
Fighting Parkinson’s disease: The return of the mitochondria13
Visualization of mitophagy using LysoKK, a 7-nitro-2,1,3-benzoxadiazole-(arylpropyl)benzylamine derivative13
The Parkinson’s disease-associated mutation LRRK2 G2385R alters mitochondrial biogenesis via the PGC-1α-TFAM pathway13
RTN3 deficiency exacerbates cisplatin-induced acute kidney injury through the disruption of mitochondrial stability13
Defining ER-mitochondria contact dynamics in Plasmodium falciparum by targeting component of phospholipid synthesis pathway, phosphatidylserine synthase (PfPSS)13
Targeting the mitochondria in chronic respiratory diseases13
WITHDRAWN: Mitochondrial oxygen respiration is associated with loneliness in a sample of community-dwelling adults13
Aromatic hydrocarbon receptors in mitochondrial biogenesis and function12
Longitudinal changes in mitochondrial-associated measures and insulin resistance in youth with perinatally-acquired HIV in the U.S12
Cancer/Testis Antigen 55 is required for cancer cell proliferation and mitochondrial DNA maintenance12
Perceived association of mood and symptom severity in adults with mitochondrial diseases12
Auditory neuropathy spectrum disorder and related auditory features in patients with hearing loss associated with the MT-TS1 m.7471dup variant12
Altered brown adipose tissue mitochondrial function in newborn fragile X syndrome mice12
Editorial Board12
Role of mitophagy in pulmonary hypertension: Targeting the mechanism and pharmacological intervention12
Differentiation activates mitochondrial OPA1 processing in myoblast cell lines12
Ancestry affects the transcription of small mitochondrial RNAs in human lymphocytes12
Severe acute respiratory syndrome coronaviruses contributing to mitochondrial dysfunction: Implications for post-COVID complications11
Miro1- a key player in β-cell function and mitochondrial dynamics under diabetes mellitus11
Receptor-mediated mitophagy: An emerging therapeutic target in acute kidney injury11
Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies11
The constraints of allotopic expression11
Type 1 diabetes mellitus: Inflammation, mitophagy, and mitochondrial function11
Analysis of compound heterozygous and homozygous mutations found in peripheral subunits of human respiratory Complex I, NDUFS1, NDUFS2, NDUFS8 and NDUFV1, by modeling in the E. coli enzyme11
MitoQuicLy: A high-throughput method for quantifying cell-free DNA from human plasma, serum, and saliva10
HIV-1 gp120 protein promotes HAND through the calcineurin pathway activation10
Machine learning-based 3D segmentation of mitochondria in polarized epithelial cells10
Sirtuin 3 and mitochondrial permeability transition pore (mPTP): A systematic review10
Identifying the mitochondrial metabolism network by integration of machine learning and explainable artificial intelligence in skeletal muscle in type 2 diabetes10
Recent trends of natural based therapeutics for mitochondria targeting in Alzheimer’s disease10
Early cardiac mechanics abnormalities in patients with mitochondrial diseases10
Transplantation of astrocyte-derived mitochondria into injured astrocytes has a protective effect following stretch injury10
Mitochondria in aging and age-associated diseases10
The impact of TK2 deficiency syndrome and its treatment by nucleoside therapy on quality of life10
DDQ anti-aging properties expressed with improved mitophagy in mutant tau HT22 neuronal cells10
Mitochondrial mechanisms in Treg cell regulation: Implications for immunotherapy and disease treatment9
Temporal changes and control variables of growth differentiation factor 15 levels during the first week of life in hospitalised newborn infants9
Deciphering the role of MitomiRs in cancer: A comprehensive review9
SIRT6 suppresses colon cancer growth by inducing apoptosis and autophagy through transcriptionally down-regulating Survivin9
Associations of mitochondrial genomic variation with successful neurological aging9
Mitochondrial tRNA variants in 811 Chinese probands with Leber’s hereditary optic neuropathy9
Diagnosis of primary mitochondrial disorders -Emphasis on myopathological aspects9
Development of Leigh syndrome with a high probability of cardiac manifestations in infantile-onset patients with m.14453G > A9
PKD regulates mitophagy to prevent oxidative stress and mitochondrial dysfunction during mouse oocyte maturation9
Mitochondrial dynamics and mitochondrial autophagy: Molecular structure, orchestrating mechanism and related disorders9
Mitochondrial and metabolic features of salugenesis and the healing cycle9
The maternal genetic origin and diversity of the extant populations of the Ladakh region in India8
Decoding mitochondrial quality control mechanisms: Identifying treatment targets for enhanced cellular health8
Role of Rmd9p in 3′-end processing of mitochondrial 15S rRNA in Saccharomyces cerevisiae8
Machine learning to predict mitochondrial diseases by phenotypes8
Global view of dynamic expression and precise mapping of mitochondrial tRNAs-derived fragments during stressed conditions in S. pombe8
β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence8
Altered insulin pathway compromises mitochondrial function and quality control both in in vitro and in vivo model systems8
GenEye24: Novel rapid screening test for the top-3 Leber’s Hereditary Optic Neuropathy pathogenic sequence variants8
Mitochondrial bioenergetics and cytometric characterization of a synaptosomal preparation from mouse brain cortex8
Hemispheric analysis of mitochondrial Complex I and II activity in the mouse model of ischemia-reperfusion-induced injury8
Assessment of mitochondrial DNA copy number variation relative to nuclear DNA quantity between different tissues8
Presence and transmission of mitochondrial heteroplasmic mutations in human populations of European and African ancestry7
Mitochondrial DNA abundance and circulating metabolomic profiling: Multivariable-adjusted and Mendelian randomization analyses in UK Biobank7
Role of mitochondrial potassium channels in ageing7
Mitochondria determine response to anti-programmed cell death protein-1 (anti-PD-1) immunotherapy: An evidence-based hypothesis7
Clinical and genetic spectrum of mitochondrial DNA depletion syndromes: A report of 6 cases with 4 novel variants7
Relationships of mitochondrial DNA mutations and select clinical diagnoses in perinatally HIV- and ART-exposed uninfected children7
Extracellular vesicles as carriers for mitochondria: Biological functions and clinical applications7
Mitochondrial Mechanisms in Temozolomide Resistance: Unraveling the Complex Interplay and Therapeutic Strategies in Glioblastoma7
Corrigendum to “Decreased membrane cholesterol in liver mitochondria of the point mutation mouse model of juvenile Niemann-Pick C1, Npc1” [Mitochondrion 51 (2019) 15–21]7
Actin-related protein 4: An unconventional negative regulator of mitochondrial calcium in protozoan parasite Leishmania7
Editorial Board7
The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches7
Understanding the molecular basis of anti-fibrotic potential of intranasal curcumin and its association with mitochondrial homeostasis in silica-exposed mice7
Beneficial effects of mitophagy enhancers on amyloid beta-induced mitochondrial and synaptic toxicities in Alzheimer’s disease6
Blood biomarkers for assessment of mitochondrial dysfunction: An expert review6
Large-scale screens identify a 19-Gene MitoScore for improved risk assessment in acute myeloid leukemia6
Interplay of mitochondria-associated membrane proteins and autophagy: Implications in neurodegeneration6
In vitro models of insulin resistance: Mitochondrial coupling is differently affected in liver and muscle cells6
Energy Metabolism Focused Analysis of Sexual Dimorphism in Biological Aging and Hypothesized Sex-specificity in Sirtuin Dependency6
Ultrastructural and functional recovery of mitochondria and improved developmental competence by melatonin in oxidatively stressed porcine oocytes6
The m.3890G>A/MT-ND1 mtDNA rare pathogenic variant: Expanding clinical and MRI phenotypes6
Mitochondrial dysfunction in diabetic neuropathy: Impaired mitophagy triggers NLRP3 inflammasome6
Interactions between nuclear and mitochondrial SNPs and Parkinson’s disease risk6
Mitochondrial DNA mutation pathogenicity score and neurocognitive performance in persons with HIV6
Telomere length determines the mitochondrial copy number in blastocyst-stage embryos6
Image-based quantification of mitochondrial iron uptake via Mitoferrin-26
Simulated microgravity triggers DNA damage and mitochondria-mediated apoptosis through ROS generation in human promyelocytic leukemic cells6
Editorial Board6
Erodible thermogelling hydrogels for localized mitochondrial transplantation to the spinal cord6
Endurance swimming exacerbates mitochondrial myopathy in mice with high mtDNA deletions6
The mitochondrial chaperone TRAP-1 regulates the glutamine metabolism in tumor cells6
Revolutionizing cellular energy: The convergence of mitochondrial dynamics and delivery technologies6
ER stress-associated transcription factor CREB3 is essential for normal Ca2+, ATP, and ROS homeostasis6
mitoPADdb: A database of mitochondrial proteins associated with diseases6
Different platforms for mitomiRs in mitochondria: Emerging facets in regulation of mitochondrial functions6
Plant mitochondria import DNA via alternative membrane complexes involving various VDAC isoforms5
A novel, conserved and possibly functional motif “WHWGHTW” in mitochondrial transcription across Bilateria5
Positive regulation of endothelial Tom70 by metformin as a new mechanism against cardiac microvascular injury in diabetes5
Iron chelation mitigates mitochondrial dysfunction and oxidative stress by enhancing nrf2-mediated antioxidant responses in the renal cortex of a murine model of type 2 diabetes5
Ancient mitogenomes suggest complex maternal history of one of the oldest settlements of western India5
Cyt b gene as a valid molecular authentication marker of cow leathers5
AutomAted RepeaT Identifier (AARTI): A tool to identify common, polymorphic, and unique microsatellites5
ATPAF1 deficiency impairs ATP synthase assembly and mitochondrial respiration5
Regulation of mitochondrial network homeostasis by O-GlcNAcylation5
Editorial Board5
NUDT6 and NUDT9, two mitochondrial members of the NUDIX family, have distinct hydrolysis activities5
The Schizosaccharomyces pombe DEAD-box protein Mss116 is required for mitoribosome assembly and mitochondrial translation5
Mitochondrial dynamics related neurovascular approaches in cerebral ischemic injury5
Neuroprotective effect of autologous mitochondrial transplantation against global ischemia/reperfusion injury in a rat model of cardiac arrest5
Mitochondrial transplantation: Triumphs, challenges, and impacts on nuclear genome remodelling5
Corrigendum to “Laurus nobilis ethanolic extract attenuates hyperglycemia and hyperinsulinemia-induced insulin resistance in HepG2 cell line through the reduction of oxidative stress and improvement o4
Melatonin protects against excessive autophagy-induced mitochondrial and ovarian reserve function deficiency though ERK signaling pathway in Chinese hamster ovary (CHO) cells4
Partial inhibition of mitochondrial-linked pyrimidine synthesis increases tumorigenic potential and lysosome accumulation4
Simultaneous extraction and quantification of circulating mitochondrial and nuclear DNA using a single plasma sample to predict specific molecular diagnostic implications4
A comprehensive perspective of Huntington’s disease and mitochondrial dysfunction4
Genes from oxidative phosphorylation complexes II-V and two dual-function subunits of complex I are transcribed in Viscum album despite absence of the entire mitochondrial holo-complex I4
Mitochondrial iron-sulfur cluster biogenesis and neurological disorders4
Transplanting mitochondria from gastric epithelial cells reduces the malignancy of gastric cancer4
Editorial Board4
Outlier maternal haplogroups N5 and X2 and their potential role in elevated tuberculosis prevalence among the Sahariya tribe4
SDHAF2 facilitates mitochondrial respiration through stabilizing succinate dehydrogenase and cytochrome c oxidase assemblies4
Mitochondrial DNA haplogroup, genetic ancestry, and susceptibility to Ewing sarcoma4
Understanding the neuronal synapse and challenges associated with the mitochondrial dysfunction in mild cognitive impairment and Alzheimer’s disease4
Krebs cycle derivatives, dimethyl fumarate and itaconate, control metabolic reprogramming in inflammatory human microglia cell line4
Complete mitochondrial DNA profile in stroke: A geographical matched case-control study in Spanish population4
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