International Immunopharmacology

Article	Citations
In-vitro and in-silico evaluation of rue herb for SARS-CoV-2 treatment	333
Unveiling the impact of Cancer-IgG on glioma: Insights into biological behavior and macrophage polarization dynamics	166
VX-509 (Decernotinib)-modified tolerogenic dendritic cells alleviate experimental autoimmune neuritis by promoting Th17/Treg rebalance	139
Editorial Board	133
Skin inflammation and lipid disorder induced by topical application of Mal f 1	125
A novel combination therapy using Dapagliflozin and Cycas media extract in experimentally induced diabetic wounds by targeting novel pathways in wound healing	122
PD1-TLR10 fusion protein enhances the antitumor efficacy of CAR-T cells in colon cancer	118
Designing a predictive Framework: Immune-Related Gene-Based nomogram and prognostic model for kidney renal papillary cell carcinoma	115
Procyanidin B2 targeted CCR7 expression to inhibit the senescence-associated secretory phenotype through the NF-κB pathway to promote osteogenic differentiation of periodontal ligament stem cells in p	109
27-hydroxycholesterol roles in respiratory disease pathogenesis	108
Sunitinib attenuates reactive MDSCs enhancing anti-tumor immunity in HNSCC	107
Laterosporulin25: A probiotically produced, novel defensin-like bacteriocin and its immunogenic properties	106
Therapeutic potential of microglia-derived extracellular vesicles in ischemic stroke	103
Acertannin attenuates LPS-induced inflammation by interrupting the binding of LPS to the TLR4/MD2 complex and activating Nrf2-mediated HO-1 activation	100
Hesperetin alleviates PM2.5-induced lung injury by inhibiting ferroptosis in an Nrf2-dependent manner	93
Activated intestinal microbiome-associated tryptophan metabolism upregulates aryl hydrocarbon receptor to promote osteoarthritis in a rat model	93
GRK2-facilitated TLR4 signaling promotes cardiac fibrosis in rheumatic mice	93
Spermidine attenuates monocrotaline-induced pulmonary arterial hypertension in rats by inhibiting purine metabolism and polyamine synthesis-associated vascular remodeling	89
Single‑cell RNA sequencing reveals heterogeneity in ovarian cancer and constructs a prognostic signature for prognostic prediction and immunotherapy	89
Comprehensive analysis of MFN2 as a prognostic biomarker associated with immune cell infiltration in renal clear cell carcinoma	86
MCTR1 ameliorates LPS-induced lung injury by inhibiting neutrophil reverse transendothelial migration	85
Role of S100A1, S100A4, S100A8/A9 and S100B in myocardial infarction and heart failure	83
Solubilized curcuminoid complex prevents extensive immunosuppression through immune restoration and antioxidant activity: Therapeutic potential against SARS-CoV-2 (COVID-19)	81
Exploring dysregulated immune response genes and endothelial dysfunction biomarkers as predictors of severe COVID-19	81
High-titer rheumatologic markers in serum of veterans with severe pulmonary complications 25–30 years after sulfur mustard exposure	81

“The effect of 48-weeks azithromycin therapy on levels of soluble biomarkers associated with HIV-associated chronic lung disease”	79
Edaravone attenuates cerebral inflammation by inhibiting mast cells degranulation via ROS/STIM1 signaling pathway in HIE model	78
Macrophage-specific deletion of HO-1 aggravates radiation-induced lung injury through an PP2A-dependent manner	75
Multi-omics analysis reveals dynamic proteomic remodeling and metabonomic dysregulation underlying cytokine release syndrome in CAR-T-treated B-ALL	74
Safety and immunogenicity of the ChAdOx1, MVA-MERS-S, and GLS-5300 DNA MERS-CoV vaccines	72
Bovine serum albumin nanoparticles containing Poly (I:C) can enhance the neutralizing antibody response induced by envelope protein of Orthoflavivirus zikaense	71
Intravenous immunoglobulin therapy for HIV-associated Guillain–Barré syndrome	69
Expression of extracellular HSP90α in pre- and post-treatment samples of driver-gene-negative non-small cell lung cancer	69
Editorial Board	69
Cold-inducible RNA-binding protein induces inflammatory responses via NF-κB signaling pathway in normal human bronchial epithelial cells infected with streptococcus pneumoniae	67
Facial palsy induced by immune checkpoint blockade: A systematic analysis of clinical trials and a pharmacovigilance study of postmarketing data	67
Using immune clusters for classifying Mycobacterium tuberculosis infection	67
SLAMF3 promotes Th17 differentiation and is reversed by iguratimod through JAK1/STAT3 pathway in primary Sjögren's syndrome	67
SRSF10 facilitates HCC growth and metastasis by suppressing CD8+T cell infiltration and targeting SRSF10 enhances anti-PD-L1 therapy	65
Dapagliflozin alleviated seizures and cognition impairment in pilocarpine induced status epilepticus via suppressing microglia-mediated neuroinflammation and oxidative stress	65
Gentiopicroside attenuates collagen-induced arthritis in mice via modulating the CD147/p38/NF-κB pathway	65
Curative effects of crocin in ulcerative colitis via modulating apoptosis and inflammation	65
Codelivery of triptolide and IFN-γ to boost antitumor immunity for triple-negative breast cancer	64
Pathological insights into activin A: Molecular underpinnings and therapeutic prospects in various diseases	63
Histamine deficiency exacerbates cisplatin-induced ferroptosis in cochlea hair cells of HDC knockout mice	62
Dual-sensitive gelatin-coated chitosan microparticles for targeted semaglutide pulmonary delivery: a novel approach to enhancing anti-inflammatory and anti-fibrotic effects	61
Isorhamnetin alleviates ferroptosis-mediated colitis by activating the NRF2/HO-1 pathway and chelating iron	60
Comprehensive characteristics of pulmonary antineutrophil cytoplasmic antibody-associated vasculitis and the development of a predictive nomogram for mortality	60
Fut2 deficiency aggravates chronic colitis through 2-oxindole-AHR mediated cGAS-STING pathway	59
Pellino2 accelerate inflammation and pyroptosis via the ubiquitination and activation of NLRP3 inflammation in model of pediatric pneumonia	59
NY-ESO-1 in Triple-Negative Breast Cancer: Systematic Review, Meta-Analysis, and Immunotherapeutic Implications	59
Tumor microenvironment and immunometabolic reprogramming in pancreatic ductal adenocarcinoma: Barriers and breakthroughs in immunotherapy	59
Deletion of FAM76B histidine-rich region enhances macrophage-mediated osteosarcoma inhibition via liquid-liquid phase separation	59
Immunoregulatory kinases and T-cell pathways in DNA-damage response and autoimmune inflammation: Emerging roles of BUB1 and IGFL2	59
Sinensetin attenuates LPS-induced acute pulmonary inflammation in mice and RAW264.7 cells by modulating NF-κB p65-mediated immune resistance and STAT3-mediated tissue resilience	59
Efficacy and safety of tofacitinib in the treatment of adults with lichen planopilaris: A randomized placebo-controlled trial	58
Immunosenescence as a convergence pathway in neurodegeneration	58
CircMETTL14(11)S upregulated METTL14 and induced CXCR4 to aggravate endothelial inflammation and atherosclerosis	58
Profiling inflammatory mechanisms, hyperphosphorylated tau of hippocampal tissue and spatial memory following vitamin D3 treatment in the mice model of vascular dementia	58
Exosomal Rspondin3 serves as a master regulator of immunometabolic repair in sepsis: synergistic activation of macrophage M2 polarization and endothelial BMP10 signaling	57
An “On Demand” canakinumab regimen for treating children with Colchicine-Resistant familial Mediterranean fever – A multicentre study	57
Hypoxia-induced Semaphorin 3A promotes the development of endometriosis through regulating macrophage polarization	56
Lactic acid-induced M2-like macrophages facilitate tumor cell migration and invasion via the GPNMB/CD44 axis in oral squamous cell carcinoma	56
Fibroblast growth factor 9 reduces TBHP-induced oxidative stress in chondrocytes and diminishes mouse osteoarthritis by activating ERK/Nrf2 signaling pathway	56
Clinical evidence for the prognostic impact of metformin in cancer patients treated with immune checkpoint inhibitors	56
VSIG4 induces the immunosuppressive microenvironment by promoting the infiltration of M2 macrophage and Tregs in clear cell renal cell carcinoma	56
Exosomal circRNA-001264 promotes AML immunosuppression through induction of M2-like macrophages and PD-L1 overexpression	56
GDF11 alleviates spinal cord injury in rats by modulating microglia polarization through Smad2/3 and MAPK/NFκB signaling pathways	55
Amelioration of nerve demyelination by hydrogen-producing silicon-based agent in neuropathic pain rats	55
C1632 protects against LPS-induced acute lung injury by regulating AXL-mediated MAPK/NF-κB signaling pathway	55
Artesunate ameliorates Staphylococcus aureus-induced mandibular osteomyelitis and promotes osteogenic differentiation via NOD2/p65 signaling pathway	55
Urolithin a alleviates airway inflammation in acute allergic asthma by suppressing the EGFR/AKT/FOXO3a signaling pathway	55
Single-Cell RNA sequencing highlights the regulatory role of T cell marker genes Ctla4, Ccl5 and Tcf7 in corneal allograft rejection of mouse model	54
Single-cell RNA sequencing reveals the impact of mechanical loading on knee tibial cartilage in osteoarthritis	54
Revealing rutaecarpine’s promise: A pathway to parkinson’s disease relief through PPAR modulation	53

Fibroblast growth factor 21 mitigates lupus nephritis progression via the FGF21/Irgm 1/NLRP3 inflammasome pathway	52
Pentosan Polysulfate Sodium augments the therapeutic effect of 5-Aminosalicylic Acid in DSS colitis model; the role of IL-35 expression	52
MultiOmics analysis of metabolic dysregulation and immune features in breast cancer	52
Antagonism of CD28 blocks allergic responses in the ovalbumin-induced asthmatic model mice	52
Corrigendum to “Integrated population pharmacokinetics of immunoglobulin G following intravenous or subcutaneous administration of various immunoglobulin products in patients with primary immunodefici	52
Retraction notice to “BMSCs-derived exosomal microRNA-150-5p attenuates myocardial infarction in mice” [Int. Immunopharmacol. 93 (2021) 107389]	52
Corrigendum to “Combined diosmin and bisoprolol attenuate cobalt chloride-induced cardiotoxicity and endothelial dysfunction through modulating miR-143-3P/MAPK/MCP-1, ERK5/CXCR4, Orai-1/STIM-1 signali	52
Advances in the application of immune checkpoint inhibitors in gynecological tumors	51
The NLRP3 inflammasome inhibitor OLT1177 attenuates retinal neovascularization and microglial inflammation with neuroprotective effects	51
Tacrolimus alleviates pulmonary fibrosis progression through inhibiting the activation and interaction of ILC2 and monocytes	51
Controversial role of γδ T cells in pancreatic cancer	51
LXA4 attenuates perioperative neurocognitive disorders by suppressing neuroinflammation and oxidative stress	51
SCD1 protects acinar cells from ferroptosis during severe acute pancreatitis by balancing lipid and redox homeostasis	50
Posttreatment with dexmedetomidine aggravates LPS-induced myocardial dysfunction partly via activating cardiac endothelial α2A-AR in mice	50
Distinct inflammatory profiles in mustard lung: A study of sulfur mustard-exposed patients with serious pulmonary complications	50
Association of soluble PD-L1 and NLR combination with 1-Year mortality in patients with COVID-19	50
Exploration and Validation of Ferroptosis-Associated Genes in ADAR1 Deletion-Induced NAFLD through RNA-seq Analysis	49
Piezo1 activates Wnt5a/FZD4 signaling to promote osteogenesis and mitigates age-associated bone loss	49
Carbon monoxide-releasing molecule 2 inhibits inflammation associated with intestinal ischemia-reperfusion injury in a rat model of hemorrhagic shock	49
Berberine inhibits NLRP3 inflammasome activation by upregulating the SIRT6-AMPK pathway to prevent angiotensin II-induced fibrosis and vulnerability to atrial fibrillation	49
Lactic acid, a driver of tumor-stroma interactions	49
Dexmedetomidine therapy promotes cardiac dysfunction and increases mortality in sepsis: A translational study	49
Cuproptosis-related gene PDHX and heat stress-related HSPD1 as potential key drivers associated with cell stemness, aberrant metabolism and immunosuppression in esophageal carcinoma	49
Inhibition of CRLF1 expression by miR-8485 alleviates IL-1β-induced chondrocyte inflammation, apoptosis, and extracellular matrix degradation	49
Role of macrophages in cardiac arrhythmias: Pathogenesis and therapeutic perspectives	49
Clinical features and prognostic factors of severe cutaneous adverse drug reactions: A single-center retrospective study of 209 cases in China	49
Efficacy and safety of moxibustion as a complementary and alternative therapy for asthma: A systematic review and meta-analysis	49
Immune system roles in pathogenesis, prognosis, control, and treatment of Toxoplasma gondii infection	48
Neuronal ferroptosis and ferroptosis-mediated endoplasmic reticulum stress: Implications in cognitive dysfunction induced by chronic intermittent hypoxia in mice	48
Membranous nephropathy: Mechanistic insights and therapeutic perspectives	48
Impact of inflammation and anti-inflammatory modalities on diabetic cardiomyopathy healing: From fundamental research to therapy	48
Tripartite motif containing 59 mediates protective anti-oxidative effects in intestinal injury through Nrf2 signaling	48
Tumor-associated macrophages promote migration and invasion via modulating IL-6/STAT3 signaling in renal cell carcinoma	48
Exploring the regulatory role of mtTFA on inflammation, oxidative stress, and epigenetic alterations in COPD progressed NSCLC patients with smoking history	47
Bovine-derived α-lactalbumin exhibits cardiovascular protection against aging by ameliorating the inflammatory process in mice	47
Microcystin-LR drives hepatic meta-inflammation and insulin resistance by hijacking the PP2A-JNK signaling axis	47
SO2 activates Th17 cells through the JAK1,2/STAT3 signaling pathway	47
Macrophage crosstalk and therapies: Between tumor cells and immune cells	47
Dietary capsaicin attenuates cardiac injury after myocardial infarction in type 2 diabetic mice by inhibiting ferroptosis through activation of TRPV1 and Nrf2/HMOX1 pathway	47
Sinomenine promotes flap survival by upregulating eNOS and eNOS-mediated autophagy via PI3K/AKT pathway	47
The innate immune sensor STING accelerates neointima formation via NF-κB signaling pathway	46
AdipoRon exerts an antidepressant effect by inhibiting NLRP3 inflammasome activation in microglia via promoting mitophagy	46
Plasma levels of 12 different cytokines correlate to PD-1 inhibitor combined chemotherapy responses in advanced non-small-cell lung cancer patient	46
Review of the effects and Mechanisms of microglial autophagy in ischemic stroke	46
Calcitonin gene-related peptide-modulated macrophage phenotypic alteration regulates angiogenesis in early bone healing	46
Unravelling the role of Interleukin-12 in Neuroinflammatory mechanisms: Pathogenic pathways linking Neuroinflammation to neuropsychiatric disorders	46
A novel molecule ZYZ311 derivatized from Carvacrol ameliorates DSS-induced colitis in mice via inhibiting JAK2/STAT3	46
Toll-like receptor 2 deficiency ameliorates obesity-induced cardiomyopathy via inhibiting NF-κB signaling pathway	45
IL-37 protects against house dust mite-induced airway inflammation and airway epithelial barrier dysfunction via inhibiting store-operated calcium entry	45
Comprehensive analysis of a pyroptosis-related gene signature of clinical and biological value in acute myeloid leukaemia	45
The role of lncRNA and miRNA on the effects of occurrence and development of osteosarcoma	45
Mmu_circ_0005373 and hsa_circ_0136255 participate in the pulmonary fibrosis of systemic sclerosis	45
NOX4 regulates gastric cancer cell invasion and proliferation by increasing ferroptosis sensitivity through regulating ROS	45
Staphylococcus aureus escapes endosomes and autophagosomes via α-hemolysin	44
Nicotinamide N-methyltransferase mediates redox regulation and colonic epithelial barrier impairment by SIRT1/PPAR-γ/NLRP6/NRF2 axis in inflammatory bowel disease	44
T-cell immunoglobulin and mucin-domain containing-3 (TIM-3): Solving a key puzzle in autoimmune diseases	44
CD83 mediates the inhibitory effect of the S1PR1 agonist CYM5442 on LPS-induced M1 polarization of macrophages through the ERK-STAT-1 signaling pathway	44
WWOX protects against ferroptosis to alleviate acute lung injury by mediating p53 deacetylation	44
Unveiling the interplay between hepatocyte SATB1 and innate immunity in autoimmune hepatitis	44
CP-25 ameliorates dysfunction in the M3R-IP3R-Ca2+-AQP5 signaling pathway by inhibiting ERS in primary Sjögren's syndrome	44
Mustard lung with a unique oxidative stress profile as an independent pulmonary disease	44
Investigating the mechanism by which telomere dysfunction affects mitochondrial homeostasis in anthracosilicosis using a Terc knockout model	44
Acupressure bladder meridian alleviates anxiety disorder via HMGB1	44
Activation of NLRP3 inflammasome contributes to the inflammatory response to allergic rhinitis via macrophage pyroptosis	43
Arctigenin mitigates insulin resistance by modulating the IRS2/GLUT4 pathway via TLR4 in type 2 diabetes mellitus mice	43
Natural bioactive compounds reprogram bile acid metabolism in MAFLD: Multi-target mechanisms and therapeutic implications	43
Deletion of BMP4 impairs trophoblast function and decidual macrophage polarization via autophagy leading to recurrent spontaneous abortion	43
Combined dupilumab with immunotherapy is more effective than dupilumab alone in children with moderate-to-severe atopic dermatitis	43
Antitumor effect of invasive Lactobacillus plantarum delivering associated antigen gene sHSP between Trichinella spiralis and Lewis lung cancer cells	43
Long-term outcomes in patients with persistent EBV-DNA positivity after primary Epstein-Barr virus infection and clinical implications of rituximab therapy	42
Berberine sensitizes immune checkpoint blockade therapy in melanoma by NQO1 inhibition and ROS activation	42
Enrichment of innate immune cells from PBMC followed by triple cytokine activation for adoptive immunotherapy	42
Donepezil halts acetic acid-induced experimental colitis in rats and its associated cognitive impairment through regulating inflammatory/oxidative/apoptotic cascades: An add-on to its anti-dementia ac	42
Trichinella spiralis cystatin alleviates polymicrobial sepsis through activating regulatory macrophages	42
Bomidin attenuates inflammation of periodontal ligament stem cells and periodontitis in mice via inhibiting ferroptosis	42
Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages	42
Butyrate alleviates alcoholic liver disease-associated inflammation through macrophage regulation and polarization via the HDAC1/miR-155 axis	41
Selenium improves behavioral performance in a rat model of autism spectrum disorder by mitigating oxidative stress and modulating the Sirt1/Keap1/Nrf2/HO-1 signaling pathway	41
Antioxidant activity of 2-mercaptoethanol protects against CD8+ T cell overstimulation or accelerated exhaustion: evidence from an in vitro exhausted CD8+ T model and in vivo adoptive cell transfer	41
C1q/TNF-related protein-9 promotes diabetic wound healing by enhancing dendritic cell efferocytosis via the ATF3/SLC7A11 signaling axis	41

Toll-like receptor 4 deficiency affects the balance of osteoclastogenesis and osteoblastogenesis in periodontitis	41
METTL3-mediated m6A modification of CD36: Implications for glucose metabolism and inflammatory dysregulation in follicles of polycystic ovary syndrome	41
CXCL1 enhances COX-II expression in rheumatoid arthritis synovial fibroblasts by CXCR2, PLC, PKC, and NF-κB signal pathway	41
Identification of TAP1 as a T-cell related therapeutic target in gastric cancer by mediating oxalipliatin-related synergistic enhancement of immunotherapy	41
Comprehensive transcriptomic analyses identify the immunosuppressive effects of LLDT-8 in ART-treated SIV-infected rhesus macaques	40
Hydrogen-rich saline regulates NLRP3 inflammasome activation in sepsis-associated encephalopathy rat model	40
Treatment with sitagliptin exacerbates the M2 phenotype in macrophages in vitro	40
The human and murine immune systems: regulated by dichotomous molecules	40
Ex vivo pembrolizumab pharmacology for personalized PD-1 inhibitor therapy reveals a critical gap between receptor occupancy and T cell functionality	40
Quantitative analysis of immune cells within the tumor microenvironment of glioblastoma and their relevance for prognosis	40
Trispecific antibodies in cancer therapy: Mechanisms, clinical progress and future directions	40
Fecal microbiota transplantation affects the recovery of AD-skin lesions and enhances gut microbiota homeostasis	40
The role of cGAS-STING signaling pathway in colorectal cancer immunotherapy: Mechanism and progress	40
Exosome-derived SLC12A2-DT promotes macrophage M2 polarization-mediated hepatocellular carcinoma progression	39
Identification of monomethylsulochrin as a novel agent to ameliorate DSS-induced ulcerative colitis through dual modulation of the IL-17/TNF pathway and gut microbiota	39
Leonurine attenuates OVA-induced asthma via p38 MAPK/NF-κB signaling pathway	39
Mechanism of Keke tablets in treating post-infectious cough following influenza A virus infection based on network pharmacology, molecular docking, molecular dynamics and in vivo experiments	39
Efficacy and safety of anti-CD19 CAR-T in a mouse model of IgG4-related disease	39
Glutathione metabolic reprogramming by ferroptosis inducers potentiates cuproptosis and antitumor immunity in osteosarcoma	39
Extracellular vesicles of ADSCs inhibit ischemic stroke-induced pyroptosis through Gbp3 regulation: A role for the NLRP3/GSDMD signaling pathway	39
Intervention of neuroinflammation in the traumatic brain injury trajectory: In vivo and clinical approaches	39
Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options	39
2′, 4′-Dihydroxy-2,3-dimethoxychalcone: A pharmacological inverse agonist of RORγt ameliorating Th17-driven inflammatory diseases by regulating Th17/Treg	39
Prophylaxis strategies containing high dose intravenous methotrexate on preventing CNS relapse for patients with diffuse large B-cell lymphoma at intermediate to high risk: A study based on 12 cohorts	39
Effects of RETN polymorphisms on treatment response in rheumatoid arthritis patients receiving TNF-α inhibitors and utilization of machine-learning algorithms	38
ILC2s control obesity by regulating energy homeostasis and browning of white fat	38
Maclurin inhibits caspase-11 non-canonical inflammasome in macrophages and ameliorates acute lethal sepsis in mice	38
Farrerol alleviates cognitive impairments in chronic cerebral hypoperfusion via suppressing NLRP3 inflammasome-mediated pyroptosis	38
Molecular pathways and biological roles of melatonin and vitamin D; effects on immune system and oxidative stress	38
The E3 ubiquitin ligase RNF31 mediates the development of ulcerative colitis by regulating NLRP3 inflammasome activation	38
Targeting the mechanism of IRF3 in sepsis-associated acute kidney injury via the Hippo pathway	38
An overview of immune checkpoint therapy in autoimmune diseases	38
SERPINH1 secretion by cancer-associated fibroblasts promotes hepatocellular carcinoma malignancy through SENP3-mediated SP1/SQLE pathway	37
Macrophage-derived GSDMD promotes abdominal aortic aneurysm and aortic smooth muscle cells pyroptosis	37
Fisetin alleviates cerebral ischemia/reperfusion injury by regulating Sirt1/Foxc1/Ubqln1 pathway-mediated proteostasis	37
Ferroptosis in organ fibrosis: Mechanisms and therapeutic approaches	37
Kongensin a attenuates intervertebral disc degeneration by inhibiting TAK1-mediated PANoptosis of nucleus pulposus cells	37
Antiproliferative and apoptotic effects of (1R*,12R*)-dolabella-4(16),7,10-triene-3,13-dione (CI-A) in oral cancer cells are mediated by oxidative stress and ERK activation	37
The circRNA0001707/miR-203a-3p/TLR4 regulatory axis drives macrophage polarization in enthesitis of newly diagnosed ankylosing spondylitis	37
Ergothioneine inhibits the progression of osteoarthritis via the Sirt6/NF-κB axis both in vitro and in vivo	37
Changes in the phenotype and function of mucosal-associated invariant T cells in neutrophilic asthma	36
Highlights into historical and current immune interventions for cancer	36
SAP130 released by ferroptosis tubular epithelial cells promotes macrophage polarization via Mincle signaling in sepsis acute kidney injury	36
Haemolysis is a concerning bias in some ozone therapy approaches	36
Novel neuroglobin boosters as a therapeutic strategy for traumatic brain injury	36
Protective effects of BTK inhibition by acalabrutinib on cisplatin-induced renal and testicular injury in mice: Modulation of mTOR/AMPK, NLRP3/GSDMD-N, and apoptotic pathways.	36
Molecular feature of arterial remodeling in the brain arteriovenous malformation revealed by arteriovenous shunt rat model and RNA sequencing	36
Ginsenoside 20(R)-Rg3 enhances natural killer cell activity by increasing activating receptor expression through the MAPK/ERK signaling pathway	36
Tetrandrine alleviates atherosclerosis via inhibition of STING-TBK1 pathway and inflammation in macrophages	36
Understanding the relationship between silicone implants, tumor antigens, and breast cancer risk: An immunological study in rats	36
Combining ulinastatin with TIENAM improves the outcome of sepsis induced by cecal ligation and puncture in mice by reducing inflammation and regulating immune responses	36
Editorial Board	36
Coptisine alleviates intestinal barrier dysfunction and inflammation in TNBS-induced colitis rats and LPS-stimulated human intestinal Caco-2 cells	36
The roles of orphan nuclear receptor 4 group A1 and A2 in fibrosis	36
Cyclic helix B peptide alleviates liver fibrosis via attenuating ROS-mediated pyroptosis	36
SZ168 alleviates bleomycin-induced pulmonary fibrosis by inhibiting podoplanin-induced platelet activation	36
Targeting ferroptosis as a cell death pathway in Melanoma: From molecular mechanisms to skin cancer treatment	36
Activation of Wnt/β-catenin signaling promotes immune evasion via the β-catenin/IKZF1/CCL5 axis in hepatocellular carcinoma	35
The potential effects of festidinol treatment against the NLRP3 inflammasome and pyroptosis in D-galactose and aluminum chloride–induced Alzheimer's-like pathology in mouse brain	35
Agomelatine improves streptozotocin-induced diabetic nephropathy through melatonin receptors/SIRT1 signaling pathway	35
Macrophage extracellular traps promote peritoneal fibrosis through the ROS/TGF-β/Smad pathway under high-glucose dialysis conditions	35
Maackiain protects against sepsis via activating AMPK/Nrf2/HO-1 pathway	35
Therapeutic effect of (5R)-5-hydroxytriptolide (LLDT-8) in SIV infected rhesus monkeys	35
Nogo-B inhibition restricts ulcerative colitis via inhibiting p68/miR-155 signaling pathway	35
The effects of therapeutic hypothermia on the expression of DKK3 and myocardial ischemia-reperfusion injury	35
The neutrophil–NET Axis in ovarian cancer: Drivers of tumor microenvironment remodeling and therapeutic resistance	35
Plumbagin improves myocardial fibrosis after myocardial infarction by inhibiting the AKT/mTOR pathway to upregulate autophagy levels	35
Performance of assessment tools in predicting neural autoantibody positivity in patients with seizures	35
Macrophage β-arrestin-1 deteriorates DSS-induced colitis through interaction with NF-κB signaling	35
Chemokine CCL5 immune subtypes of human liver cancer with prognostic significance	35
Investigation into the anti-airway inflammatory role of the PI3Kγ inhibitor JN-PK1: An in vitro and in vivo study	35
Urine PD-L1 is a tumor tissue candidate substitute and is associated with poor survival in muscle-invasive bladder cancer patients	35
LncRNA Kcnq1ot1relieves neuropathic pain through downregulation of Myd88	34
The protective effect of intranasal immunization with influenza virus recombinant adenovirus vaccine on mucosal and systemic immune response	34
Interleukin 8 exacerbates age-related hearing loss through regulating perivascular-resident macrophage-like melanocytes viability and the permeability of the endothelial cells	34
Eucalyptol, limonene and pinene enteric capsules attenuate airway inflammation and obstruction in lipopolysaccharide-induced chronic bronchitis rat model via TLR4 signaling inhibition	34
LILRB1+ immune cell infiltration identifies immunosuppressive microenvironment and dismal outcomes of patients with ovarian cancer	34
Unveiling the mystery of ILC3s: Their functions and interactions in mucosal immunity	34
Lavandula angustifolia essential oil attenuates chronic prostatitis by inhibiting PI3K/AKT and NF-κB signaling pathways	34
A modulatory effect of L-arginine supplementation on anticancer effects of chemoimmunotherapy in colon cancer-bearing aged mice	34
Development and validation of neutrophil extracellular traps-derived signature to predict the prognosis for osteosarcoma patients	34
Salvianolic acid C attenuates liver fibrosis and inhibites hepatic stellate cell activation by targeting FAP/TβRI/SMAD axis	34
Innate immune tolerance against adolescent intermittent alcohol exposure-induced behavioral abnormalities in adult mice	33
Cannabinoid receptor 2 alleviates sepsis-associated acute lung injury by modulating maturation of dendritic cells	33
EGR2 promotes liver cancer metastasis by enhancing IL-8 expression through transcription regulation of PDK4 in M2 macrophages	33
Corydaline attenuates osteolysis in rheumatoid arthritis via mitigating reactive oxygen species production and suppressing calcineurin-Nfatc1 signaling	33
5-aminolaevulinic acid with sodium ferrous citrate alleviated kidney injury and fibrosis in a unilateral ureteral obstruction model	33
Peptide nanovaccine in melanoma immunotherapy	33
Amomum longiligulare polysaccharide 1- PLGA nanoparticle promotes the immune activities of T lymphocytes and dendritic cells	33
Acteoside exerts immunomodulatory effects on dendritic cells via aryl hydrocarbon receptor activation and ameliorates Th2-mediated allergic asthma by inducing Foxp3+ regulatory T cells	33
Edaravone alleviates methotrexate-induced testicular injury in rats: Implications on inflammation, steroidogenesis, and Akt/p53 signaling	33
Prx5 overexpression protect against doxorubicin-induced cardiotoxicity by inhibiting oxidative stress and inflammation via the TLR4/NF-κB pathway	33
IMM-H004 attenuates neutrophil pyroptosis following ischemic stroke via a CKLF1 dependent mechanism	33
Celastrol inhibits intrahepatic cholangiocarcinogenesis through dual suppression of glycolysis and tumor-associated macrophages	33
Protocatechuic aldehyde ameliorates psoriasis-like skin inflammation and represses keratinocyte-derived IL-1α and CXCL9 via inhibiting STAT3 activation	33