International Immunopharmacology

Article	Citations
Safety and immunogenicity of the ChAdOx1, MVA-MERS-S, and GLS-5300 DNA MERS-CoV vaccines	510
Identification of TAP1 as a T-cell related therapeutic target in gastric cancer by mediating oxalipliatin-related synergistic enhancement of immunotherapy	286
NOX4 regulates gastric cancer cell invasion and proliferation by increasing ferroptosis sensitivity through regulating ROS	268
The innate immune sensor STING accelerates neointima formation via NF-κB signaling pathway	169
Towards exertion of immunotherapeutics in the treatment of colorectal cancer; adverse sides, challenges, and future directions	153
Dietary capsaicin attenuates cardiac injury after myocardial infarction in type 2 diabetic mice by inhibiting ferroptosis through activation of TRPV1 and Nrf2/HMOX1 pathway	146
Hypoxia-induced Semaphorin 3A promotes the development of endometriosis through regulating macrophage polarization	142
Using immune clusters for classifying Mycobacterium tuberculosis infection	128
2′, 4′-Dihydroxy-2,3-dimethoxychalcone: A pharmacological inverse agonist of RORγt ameliorating Th17-driven inflammatory diseases by regulating Th17/Treg	106
Dexmedetomidine therapy promotes cardiac dysfunction and increases mortality in sepsis: A translational study	90
Efficacy and safety of moxibustion as a complementary and alternative therapy for asthma: A systematic review and meta-analysis	87
Clinical relevance of Alternaria alternata sensitization in patients within type 2-high and type 2-low asthma	87
Boldenone undecylenate disrupts the immune system and induces autoimmune clinical hypothyroidism in rats: Vitamin C ameliorative effects	85
Macrophage crosstalk and therapies: Between tumor cells and immune cells	83
Fut2 deficiency aggravates chronic colitis through 2-oxindole-AHR mediated cGAS-STING pathway	81
Effects of RETN polymorphisms on treatment response in rheumatoid arthritis patients receiving TNF-α inhibitors and utilization of machine-learning algorithms	78
Prophylaxis strategies containing high dose intravenous methotrexate on preventing CNS relapse for patients with diffuse large B-cell lymphoma at intermediate to high risk: A study based on 12 cohorts	77
Acertannin attenuates LPS-induced inflammation by interrupting the binding of LPS to the TLR4/MD2 complex and activating Nrf2-mediated HO-1 activation	76
Sinomenine promotes flap survival by upregulating eNOS and eNOS-mediated autophagy via PI3K/AKT pathway	76
“The effect of 48-weeks azithromycin therapy on levels of soluble biomarkers associated with HIV-associated chronic lung disease”	73
Spermidine attenuates monocrotaline-induced pulmonary arterial hypertension in rats by inhibiting purine metabolism and polyamine synthesis-associated vascular remodeling	72
Anti-DLL4 ameliorates toluene diisocyanate-induced experimental asthma by inhibiting Th17 response	71
T-cell immunoglobulin and mucin-domain containing-3 (TIM-3): Solving a key puzzle in autoimmune diseases	70
Highlights into historical and current immune interventions for cancer	70
Extracellular vesicles of ADSCs inhibit ischemic stroke-induced pyroptosis through Gbp3 regulation: A role for the NLRP3/GSDMD signaling pathway	69

Tacrolimus alleviates pulmonary fibrosis progression through inhibiting the activation and interaction of ILC2 and monocytes	67
Profiling inflammatory mechanisms, hyperphosphorylated tau of hippocampal tissue and spatial memory following vitamin D3 treatment in the mice model of vascular dementia	66
Maclurin inhibits caspase-11 non-canonical inflammasome in macrophages and ameliorates acute lethal sepsis in mice	65
METTL3-mediated m6A modification of CD36: Implications for glucose metabolism and inflammatory dysregulation in follicles of polycystic ovary syndrome	65
In-vitro and in-silico evaluation of rue herb for SARS-CoV-2 treatment	64
Bovine serum albumin nanoparticles containing Poly (I:C) can enhance the neutralizing antibody response induced by envelope protein of Orthoflavivirus zikaense	63
Tripartite motif containing 59 mediates protective anti-oxidative effects in intestinal injury through Nrf2 signaling	63
Unveiling the impact of Cancer-IgG on glioma: Insights into biological behavior and macrophage polarization dynamics	63
The role of lncRNA and miRNA on the effects of occurrence and development of osteosarcoma	62
Association between γδ T cells and clinicopathological features of breast cancer	62
Increased infiltration of CD8 T cells in recurrent glioblastoma patients is a useful biomarker for assessing the response to combined bevacizumab and lomustine therapy	62
Toll-like receptor 4 deficiency affects the balance of osteoclastogenesis and osteoblastogenesis in periodontitis	62
Histamine deficiency exacerbates cisplatin-induced ferroptosis in cochlea hair cells of HDC knockout mice	61
Cold-inducible RNA-binding protein induces inflammatory responses via NF-κB signaling pathway in normal human bronchial epithelial cells infected with streptococcus pneumoniae	61
AdipoRon exerts an antidepressant effect by inhibiting NLRP3 inflammasome activation in microglia via promoting mitophagy	60
Corrigendum to “Baicalin suppresses IL-1β-induced expression of inflammatory cytokines via blocking NF-κB in human osteoarthritis chondrocytes and shows protective effect in mice osteoarthritis models	60
Mmu_circ_0005373 and hsa_circ_0136255 participate in the pulmonary fibrosis of systemic sclerosis	59
Corrigendum to “Combined diosmin and bisoprolol attenuate cobalt chloride-induced cardiotoxicity and endothelial dysfunction through modulating miR-143-3P/MAPK/MCP-1, ERK5/CXCR4, Orai-1/STIM-1 signali	58
Therapeutic potential of microglia-derived extracellular vesicles in ischemic stroke	58
Cuproptosis-related gene PDHX and heat stress-related HSPD1 as potential key drivers associated with cell stemness, aberrant metabolism and immunosuppression in esophageal carcinoma	58
Association of soluble PD-L1 and NLR combination with 1-Year mortality in patients with COVID-19	57
Corrigendum to “Integrated population pharmacokinetics of immunoglobulin G following intravenous or subcutaneous administration of various immunoglobulin products in patients with primary immunodefici	57
Role of macrophages in cardiac arrhythmias: Pathogenesis and therapeutic perspectives	56
Skin inflammation and lipid disorder induced by topical application of Mal f 1	56
Deletion of BMP4 impairs trophoblast function and decidual macrophage polarization via autophagy leading to recurrent spontaneous abortion	56
Sinensetin attenuates LPS-induced acute pulmonary inflammation in mice and RAW264.7 cells by modulating NF-κB p65-mediated immune resistance and STAT3-mediated tissue resilience	55
Revealing rutaecarpine’s promise: A pathway to parkinson’s disease relief through PPAR modulation	55
PD1-TLR10 fusion protein enhances the antitumor efficacy of CAR-T cells in colon cancer	55
Mustard lung with a unique oxidative stress profile as an independent pulmonary disease	54
Antagonism of CD28 blocks allergic responses in the ovalbumin-induced asthmatic model mice	54
SERPINH1 secretion by cancer-associated fibroblasts promotes hepatocellular carcinoma malignancy through SENP3-mediated SP1/SQLE pathway	53
Dapagliflozin alleviated seizures and cognition impairment in pilocarpine induced status epilepticus via suppressing microglia-mediated neuroinflammation and oxidative stress	53
Designing a predictive Framework: Immune-Related Gene-Based nomogram and prognostic model for kidney renal papillary cell carcinoma	52
Single‑cell RNA sequencing reveals heterogeneity in ovarian cancer and constructs a prognostic signature for prognostic prediction and immunotherapy	52
Calcitonin gene-related peptide-modulated macrophage phenotypic alteration regulates angiogenesis in early bone healing	52
Infliximab and tocilizumab reduce anxiety-like behavior, improve cognitive performance and reverse neuropathological alterations in juvenile rats with severe autoimmune arthritis	52
LXA4 attenuates perioperative neurocognitive disorders by suppressing neuroinflammation and oxidative stress	51
CD83 mediates the inhibitory effect of the S1PR1 agonist CYM5442 on LPS-induced M1 polarization of macrophages through the ERK-STAT-1 signaling pathway	51
Pathological insights into activin A: Molecular underpinnings and therapeutic prospects in various diseases	51
Procyanidin B2 targeted CCR7 expression to inhibit the senescence-associated secretory phenotype through the NF-κB pathway to promote osteogenic differentiation of periodontal ligament stem cells in p	51
ILC2s control obesity by regulating energy homeostasis and browning of white fat	50
Pentosan Polysulfate Sodium augments the therapeutic effect of 5-Aminosalicylic Acid in DSS colitis model; the role of IL-35 expression	50
VSIG4 induces the immunosuppressive microenvironment by promoting the infiltration of M2 macrophage and Tregs in clear cell renal cell carcinoma	50
Editorial Board	49
VX-509 (Decernotinib)-modified tolerogenic dendritic cells alleviate experimental autoimmune neuritis by promoting Th17/Treg rebalance	49
Role of S100A1, S100A4, S100A8/A9 and S100B in myocardial infarction and heart failure	48
Exploring the regulatory role of mtTFA on inflammation, oxidative stress, and epigenetic alterations in COPD progressed NSCLC patients with smoking history	48
Enrichment of innate immune cells from PBMC followed by triple cytokine activation for adoptive immunotherapy	48
Ferroptosis in organ fibrosis: Mechanisms and therapeutic approaches	48
Safety and efficacy of rituximab in connective tissue disease-associated interstitial lung disease: A systematic review and meta-analysis	48

Combinatorial in silico and in vivo evaluation of immune response elicitation by the affibody ZHER2	47
Retraction notice to “BMSCs-derived exosomal microRNA-150-5p attenuates myocardial infarction in mice” [Int. Immunopharmacol. 93 (2021) 107389]	47
Evaluating the efficacy and safety of immune checkpoint inhibitors by detecting the exposure-response: An inductive review	47
Changes in the phenotype and function of mucosal-associated invariant T cells in neutrophilic asthma	46
SLAMF3 promotes Th17 differentiation and is reversed by iguratimod through JAK1/STAT3 pathway in primary Sjögren's syndrome	46
Acupressure bladder meridian alleviates anxiety disorder via HMGB1	46
Distinct inflammatory profiles in mustard lung: A study of sulfur mustard-exposed patients with serious pulmonary complications	45
Inhibition of CRLF1 expression by miR-8485 alleviates IL-1β-induced chondrocyte inflammation, apoptosis, and extracellular matrix degradation	45
Quantitative analysis of immune cells within the tumor microenvironment of glioblastoma and their relevance for prognosis	45
Single-Cell RNA sequencing highlights the regulatory role of T cell marker genes Ctla4, Ccl5 and Tcf7 in corneal allograft rejection of mouse model	45
Expression of extracellular HSP90α in pre- and post-treatment samples of driver-gene-negative non-small cell lung cancer	45
Unveiling the interplay between hepatocyte SATB1 and innate immunity in autoimmune hepatitis	45
Facial palsy induced by immune checkpoint blockade: A systematic analysis of clinical trials and a pharmacovigilance study of postmarketing data	45
High-titer rheumatologic markers in serum of veterans with severe pulmonary complications 25–30 years after sulfur mustard exposure	45
Exploring dysregulated immune response genes and endothelial dysfunction biomarkers as predictors of severe COVID-19	44
A novel combination therapy using Dapagliflozin and Cycas media extract in experimentally induced diabetic wounds by targeting novel pathways in wound healing	44
Plasma levels of 12 different cytokines correlate to PD-1 inhibitor combined chemotherapy responses in advanced non-small-cell lung cancer patient	44
Antitumor effect of invasive Lactobacillus plantarum delivering associated antigen gene sHSP between Trichinella spiralis and Lewis lung cancer cells	44
Targeting the mechanism of IRF3 in sepsis-associated acute kidney injury via the Hippo pathway	44
Activated intestinal microbiome-associated tryptophan metabolism upregulates aryl hydrocarbon receptor to promote osteoarthritis in a rat model	44
Review of the effects and Mechanisms of microglial autophagy in ischemic stroke	44
Solubilized curcuminoid complex prevents extensive immunosuppression through immune restoration and antioxidant activity: Therapeutic potential against SARS-CoV-2 (COVID-19)	44
Advances in the application of immune checkpoint inhibitors in gynecological tumors	44
Leonurine attenuates OVA-induced asthma via p38 MAPK/NF-κB signaling pathway	44
The role of cGAS-STING signaling pathway in colorectal cancer immunotherapy: Mechanism and progress	43
C1632 protects against LPS-induced acute lung injury by regulating AXL-mediated MAPK/NF-κB signaling pathway	43
Treatment with sitagliptin exacerbates the M2 phenotype in macrophages in vitro	43
The impact of long-term oral exposure to low doses of acrylamide on the hematological indicators, immune functions, and splenic tissue architecture in rats	43
Editorial Board	43
Carbon monoxide-releasing molecule 2 inhibits inflammation associated with intestinal ischemia-reperfusion injury in a rat model of hemorrhagic shock	43
SRSF10 facilitates HCC growth and metastasis by suppressing CD8+T cell infiltration and targeting SRSF10 enhances anti-PD-L1 therapy	43
Membranous nephropathy: Mechanistic insights and therapeutic perspectives	42
Efficacy and safety of anti-CD19 CAR-T in a mouse model of IgG4-related disease	42
MicroRNA-155 and antiviral immune responses	42
Fibroblast growth factor 9 reduces TBHP-induced oxidative stress in chondrocytes and diminishes mouse osteoarthritis by activating ERK/Nrf2 signaling pathway	42
Laterosporulin25: A probiotically produced, novel defensin-like bacteriocin and its immunogenic properties	41
Fibroblast growth factor 21 mitigates lupus nephritis progression via the FGF21/Irgm 1/NLRP3 inflammasome pathway	41
Comprehensive analysis of a pyroptosis-related gene signature of clinical and biological value in acute myeloid leukaemia	41
Berberine sensitizes immune checkpoint blockade therapy in melanoma by NQO1 inhibition and ROS activation	41
Comprehensive analysis of MFN2 as a prognostic biomarker associated with immune cell infiltration in renal clear cell carcinoma	41
An “On Demand” canakinumab regimen for treating children with Colchicine-Resistant familial Mediterranean fever – A multicentre study	41
Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages	41
Disulfiram attenuates MCMV-Induced pneumonia by inhibition of NF-κB/NLRP3 signaling pathway in immunocompromised mice	41
Lack of lymphocytes exacerbate heat stroke severity in male mice through enhanced inflammatory response	40
Bovine-derived α-lactalbumin exhibits cardiovascular protection against aging by ameliorating the inflammatory process in mice	40
SAP130 released by ferroptosis tubular epithelial cells promotes macrophage polarization via Mincle signaling in sepsis acute kidney injury	40
Immune system roles in pathogenesis, prognosis, control, and treatment of Toxoplasma gondii infection	40
Immunosenescence as a convergence pathway in neurodegeneration	40
Lactic acid, a driver of tumor-stroma interactions	40
Molecular feature of arterial remodeling in the brain arteriovenous malformation revealed by arteriovenous shunt rat model and RNA sequencing	39
Genetic polymorphisms of chemokine (C-X-C motif) ligand 10 gene associated with hepatitis B virus infection in a Chinese Han population	39
Isorhamnetin alleviates ferroptosis-mediated colitis by activating the NRF2/HO-1 pathway and chelating iron	39
MultiOmics analysis of metabolic dysregulation and immune features in breast cancer	39
Hesperetin alleviates PM2.5-induced lung injury by inhibiting ferroptosis in an Nrf2-dependent manner	39
IL-37 protects against house dust mite-induced airway inflammation and airway epithelial barrier dysfunction via inhibiting store-operated calcium entry	39
Clinical features and prognostic factors of severe cutaneous adverse drug reactions: A single-center retrospective study of 209 cases in China	38
Clinical evidence for the prognostic impact of metformin in cancer patients treated with immune checkpoint inhibitors	38
Activation of NLRP3 inflammasome contributes to the inflammatory response to allergic rhinitis via macrophage pyroptosis	38
Exploration and Validation of Ferroptosis-Associated Genes in ADAR1 Deletion-Induced NAFLD through RNA-seq Analysis	38
Tetrandrine alleviates atherosclerosis via inhibition of STING-TBK1 pathway and inflammation in macrophages	38
Single-cell RNA sequencing reveals the impact of mechanical loading on knee tibial cartilage in osteoarthritis	38
Ergothioneine inhibits the progression of osteoarthritis via the Sirt6/NF-κB axis both in vitro and in vivo	38
Curative effects of crocin in ulcerative colitis via modulating apoptosis and inflammation	38
Intravenous immunoglobulin therapy for HIV-associated Guillain–Barré syndrome	38
Toll-like receptor 2 deficiency ameliorates obesity-induced cardiomyopathy via inhibiting NF-κB signaling pathway	38
Molecular pathways and biological roles of melatonin and vitamin D; effects on immune system and oxidative stress	38
The roles of orphan nuclear receptor 4 group A1 and A2 in fibrosis	37
Tumor-associated macrophages promote migration and invasion via modulating IL-6/STAT3 signaling in renal cell carcinoma	37
Fecal microbiota transplantation affects the recovery of AD-skin lesions and enhances gut microbiota homeostasis	37
CXCL1 enhances COX-II expression in rheumatoid arthritis synovial fibroblasts by CXCR2, PLC, PKC, and NF-κB signal pathway	37
Codelivery of triptolide and IFN-γ to boost antitumor immunity for triple-negative breast cancer	37
Donepezil halts acetic acid-induced experimental colitis in rats and its associated cognitive impairment through regulating inflammatory/oxidative/apoptotic cascades: An add-on to its anti-dementia ac	37
Pellino2 accelerate inflammation and pyroptosis via the ubiquitination and activation of NLRP3 inflammation in model of pediatric pneumonia	37
Comprehensive transcriptomic analyses identify the immunosuppressive effects of LLDT-8 in ART-treated SIV-infected rhesus macaques	37
Comprehensive characteristics of pulmonary antineutrophil cytoplasmic antibody-associated vasculitis and the development of a predictive nomogram for mortality	37
Posttreatment with dexmedetomidine aggravates LPS-induced myocardial dysfunction partly via activating cardiac endothelial α2A-AR in mice	37
The Notch signaling pathway regulates macrophage polarization in liver diseases	37
Immunomodulation: An immune regulatory mechanism in carcinoma therapeutics	37
Arctigenin mitigates insulin resistance by modulating the IRS2/GLUT4 pathway via TLR4 in type 2 diabetes mellitus mice	37
Gentiopicroside attenuates collagen-induced arthritis in mice via modulating the CD147/p38/NF-κB pathway	37

Trichinella spiralis cystatin alleviates polymicrobial sepsis through activating regulatory macrophages	36
Intervention of neuroinflammation in the traumatic brain injury trajectory: In vivo and clinical approaches	36
An overview of immune checkpoint therapy in autoimmune diseases	36
Macrophage-derived GSDMD promotes abdominal aortic aneurysm and aortic smooth muscle cells pyroptosis	36
Kongensin a attenuates intervertebral disc degeneration by inhibiting TAK1-mediated PANoptosis of nucleus pulposus cells	36
Amelioration of nerve demyelination by hydrogen-producing silicon-based agent in neuropathic pain rats	36
Antiproliferative and apoptotic effects of (1R*,12R*)-dolabella-4(16),7,10-triene-3,13-dione (CI-A) in oral cancer cells are mediated by oxidative stress and ERK activation	35
Long-term outcomes in patients with persistent EBV-DNA positivity after primary Epstein-Barr virus infection and clinical implications of rituximab therapy	35
Lactic acid-induced M2-like macrophages facilitate tumor cell migration and invasion via the GPNMB/CD44 axis in oral squamous cell carcinoma	35
Farrerol alleviates cognitive impairments in chronic cerebral hypoperfusion via suppressing NLRP3 inflammasome-mediated pyroptosis	35
CircMETTL14(11)S upregulated METTL14 and induced CXCR4 to aggravate endothelial inflammation and atherosclerosis	35
Sunitinib attenuates reactive MDSCs enhancing anti-tumor immunity in HNSCC	35
VX765 alleviates dextran sulfate sodium-induced colitis in mice by suppressing caspase-1-mediated pyroptosis	34
Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options	34
Controversial role of γδ T cells in pancreatic cancer	34
Bomidin attenuates inflammation of periodontal ligament stem cells and periodontitis in mice via inhibiting ferroptosis	34
Neuronal ferroptosis and ferroptosis-mediated endoplasmic reticulum stress: Implications in cognitive dysfunction induced by chronic intermittent hypoxia in mice	34
SO2 activates Th17 cells through the JAK1,2/STAT3 signaling pathway	34
Hydrogen-rich saline regulates NLRP3 inflammasome activation in sepsis-associated encephalopathy rat model	34
Unravelling the role of Interleukin-12 in Neuroinflammatory mechanisms: Pathogenic pathways linking Neuroinflammation to neuropsychiatric disorders	34
Butyrate alleviates alcoholic liver disease-associated inflammation through macrophage regulation and polarization via the HDAC1/miR-155 axis	34
Impact of inflammation and anti-inflammatory modalities on diabetic cardiomyopathy healing: From fundamental research to therapy	34
Ginsenoside 20(R)-Rg3 enhances natural killer cell activity by increasing activating receptor expression through the MAPK/ERK signaling pathway	34
The E3 ubiquitin ligase RNF31 mediates the development of ulcerative colitis by regulating NLRP3 inflammasome activation	34
Exosomal circRNA-001264 promotes AML immunosuppression through induction of M2-like macrophages and PD-L1 overexpression	34
Fisetin alleviates cerebral ischemia/reperfusion injury by regulating Sirt1/Foxc1/Ubqln1 pathway-mediated proteostasis	34
L-arginine attenuates Streptococcus uberis-induced inflammation by decreasing miR155 level	33
Comparative safety of immune checkpoint inhibitors and chemotherapy in advanced non-small cell lung cancer: A systematic review and network meta-analysis	33
Editorial Board	33
Structural characterization of Alpiniae oxyphyllae fructus polysaccharide 2 and its activation effects on RAW264.7 macrophages	33
The effects of therapeutic hypothermia on the expression of DKK3 and myocardial ischemia-reperfusion injury	33
Targeting EZH2 prevents the occurrence and mitigates the development of Sjögren's syndrome in mice	33
Macrophage β-arrestin-1 deteriorates DSS-induced colitis through interaction with NF-κB signaling	33
C1q/tumor necrosis factor-related protein-9 exerts antioxidant and anti-inflammatory effects on oxygen-glucose deprivation/reoxygenation-stimulated neurons by modulating the Akt-GSK-3β-Nrf2 cascade vi	33
NPLOC4 aggravates heart failure by regulating ROS and mitochondrial function	33
ALKBH5 controlled autophagy of peripheral blood mononuclear cells by regulating NRG1 mRNA stability in ankylosing spondylitis	33
A modulatory effect of L-arginine supplementation on anticancer effects of chemoimmunotherapy in colon cancer-bearing aged mice	33
Therapeutic effect of (5R)-5-hydroxytriptolide (LLDT-8) in SIV infected rhesus monkeys	33
miR-214 could promote myocardial fibrosis and cardiac mesenchymal transition in VMC mice through regulation of the p53 or PTEN-PI3K-Akt signali pathway, promoting CF proliferation and inhibiting its n	33
Genetic predisposition to papillary thyroid carcinoma is mediated by a long non-coding RNA TINCR enhancer polymorphism	33
LncRNA-AK007111 affects airway inflammation in asthma via the regulation of mast cell function	33
Genetic association of tertiary lymphoid structure-related gene signatures with HCC based on Mendelian randomization and machine learning and construction of prognosis model	33
Haemolysis is a concerning bias in some ozone therapy approaches	33
Interleukin-35 and Interleukin-37 anti-inflammatory effect on inflammatory bowel disease: Application of non-coding RNAs in IBD therapy	33
A novel blood-based bioassay to monitor adiponectin signaling	32
Anesthetics mediated the immunomodulatory effects via regulation of TLR signaling	32
Traumatic brain Injury: Comprehensive overview from pathophysiology to Mesenchymal stem Cell-Based therapies	32
Carnosine alleviates podocyte injury in diabetic nephropathy by targeting caspase-1-mediated pyroptosis	32
Identification of the Fosl1/AMPK/autophagy axis involved in apoptotic and inflammatory effects following spinal cord injury	32
Ameliorative effect of Metformin / alpha-lipoic acid combination on diabetic nephropathy via modulation of YAP/ miR-29a/PTEN/p-AKT axis	32
Prx5 overexpression protect against doxorubicin-induced cardiotoxicity by inhibiting oxidative stress and inflammation via the TLR4/NF-κB pathway	32
Epoxymicheliolide inhibits osteoclastogenesis and resists OVX-induced osteoporosis by suppressing ERK1/2 and NFATc1 signaling	32
Combination of epidrugs with immune checkpoint inhibitors in cancer immunotherapy: From theory to therapy	32
Sulfur mustard and biological ageing: A multisystem biological health score approach as an extension of the allostatic load in Sardasht chemical veterans	32
Interleukin 8 exacerbates age-related hearing loss through regulating perivascular-resident macrophage-like melanocytes viability and the permeability of the endothelial cells	32
Growth differentiation factor 15 protects the airway by inhibiting cell pyroptosis in obese asthmatic mice through the phosphoinositide 3-kinase/AKT pathway	32
Immune checkpoints in B-cell Lymphoma: Still an Unmet challenge from Basic research to clinical practice	32
Celastrol attenuates diabetic nephropathy by upregulating SIRT1-mediated inhibition of EZH2 related wnt/β-catenin signaling	32
Activation of Wnt/β-catenin signaling promotes immune evasion via the β-catenin/IKZF1/CCL5 axis in hepatocellular carcinoma	32
Macrophage-mediated activation of the IL4I1/AhR axis is a key player in allergic rhinitis	31
Exploration of the shared diagnostic genes and mechanisms between periodontitis and primary Sjögren’s syndrome by integrated comprehensive bioinformatics analysis and machine learning	31
Loganic acid protects against ulcerative colitis by inhibiting TLR4/NF-κB mediated inflammation and activating the SIRT1/Nrf2 anti-oxidant responses in-vitro and in-vivo	31
Epigallocatechin-3-gallate ameliorates liver injury secondary to Pseudomonas aeruginosa pneumonia	31
GL13K-modified titanium regulates osteogenic differentiation via the NF-κB pathway	31
Dietary succinate supplementation alleviates DSS-induced colitis via the IL-4Rα/Hif-1α Axis	31
Peptidomic profiling of mesenchymal stem cell-derived extracellular vesicles and anti-inflammatory activity of degraded peptides	31
Precision medicine for severe asthma – Biological targeted therapy	31
The presumable effects of hydroxychloroquine and its metabolites in the treatment of systemic lupus erythematosus	31
Hydrogen-rich medium ameliorates lipopolysaccharides-induced mitochondrial fission and dysfunction in human umbilical vein endothelial cells (HUVECs) via up-regulating HO-1 expression	31
Performance of assessment tools in predicting neural autoantibody positivity in patients with seizures	31
A network pharmacology strategy to investigate the anti-osteoarthritis mechanism of main lignans components of Schisandrae Fructus	31
Cyanorona-20: The first potent anti-SARS-CoV-2 agent	31
Renal denervation improves mitochondrial oxidative stress and cardiac hypertrophy through inactivating SP1/BACH1-PACS2 signaling	31
Triptolide reduces PD-L1 through the EGFR and IFN-γ/IRF1 dual signaling pathways	31
EGR2 promotes liver cancer metastasis by enhancing IL-8 expression through transcription regulation of PDK4 in M2 macrophages	31
Corrigendum to “Attenuated Salmonella carrying siRNA-CD24 improved the effect of oxaliplatin on HCC” [Int. Immunopharmacol. 124 (2023) 111025].	31
Peptide nanovaccine in melanoma immunotherapy	30
The effects of vitamin B12 on the TLR-4/NF-κB signaling pathway in ovarian ischemia-reperfusion injury-related inflammation	30
Inhibition of DNMT1 potentiates antitumor immunity in oral squamous cell carcinoma	30
Dupilumab pharmacokinetics in Chinese healthy subjects and patients with atopic dermatitis: Results of two randomized, double-blind, placebo-controlled studies	30
Ergolide covalently binds NLRP3 and inhibits NLRP3 inflammasome-mediated pyroptosis	30
The whole process of macrophage–Treponema pallidum interactions: Opsonic phagocytosis, nonopsonic phagocytosis and active invasion	30
PCSK9 inhibitor protects against ischemic cerebral injury by attenuating inflammation via the GPNMB/CD44 pathway	30
MAPK activated kinase 2 inhibition shifts the chemokine signature in arthritis synovial fluid mononuclear cells from CXCR3 to CXCR2	30
The potential effects of festidinol treatment against the NLRP3 inflammasome and pyroptosis in D-galactose and aluminum chloride–induced Alzheimer's-like pathology in mouse brain	30
LncRNA MEG3 aggravates adipocyte inflammation and insulin resistance by targeting IGF2BP2 to activate TLR4/NF-κB signaling pathway	30
Sialic acids promote macrophage M1 polarization and atherosclerosis by upregulating ROS and autophagy blockage	30
Baicalin alleviates Mycoplasma gallisepticum-induced oxidative stress and inflammation via modulating NLRP3 inflammasome-autophagy pathway	29
LILRB1+ immune cell infiltration identifies immunosuppressive microenvironment and dismal outcomes of patients with ovarian cancer	29
Exploring the molecular mechanism of berberine for treating diabetic nephropathy based on network pharmacology	29
Low-dose ketamine inhibits neuronal apoptosis and neuroinflammation in PC12 cells via α7nAChR mediated TLR4/MAPK/NF-κB signaling pathway	29
Development and validation of neutrophil extracellular traps-derived signature to predict the prognosis for osteosarcoma patients	29
Ion channels in macrophages: Implications for disease progression	29
Donepezil and quercetin alleviate valproate-induced testicular oxidative stress, inflammation and apoptosis: Imperative roles of AMPK/SIRT1/ PGC-1α and p38-MAPK/NF-κB/ IL-1β signaling cascades	29
Activation of estrogen receptor α inhibits TLR4 signaling in macrophages and alleviates the instability of atherosclerotic plaques in the postmenopausal stage	29