International Immunopharmacology

Article	Citations
MCP-1: Function, regulation, and involvement in disease	378
COVID-19 vaccine hesitancy and related fears and anxiety	251
Effect of gut microbiota on LPS-induced acute lung injury by regulating the TLR4/NF-kB signaling pathway	238
Anti-inflammatory and M2 macrophage polarization-promoting effect of mesenchymal stem cell-derived exosomes	211
Effects of immune cells and cytokines on inflammation and immunosuppression in the tumor microenvironment	200
Nano-curcumin therapy, a promising method in modulating inflammatory cytokines in COVID-19 patients	190
Interferon β-1b in treatment of severe COVID-19: A randomized clinical trial	141
Neutrophils and COVID-19: The road so far	126
Toll-like receptors in sepsis-associated cytokine storm and their endogenous negative regulators as future immunomodulatory targets	124
The roles of macrophage polarization in the host immune response to sepsis	117
Neutrophil Extracellular Traps (NETs) and Covid-19: A new frontiers for therapeutic modality	114
Dimethyl fumarate improves cognitive deficits in chronic cerebral hypoperfusion rats by alleviating inflammation, oxidative stress, and ferroptosis via NRF2/ARE/NF-κB signal pathway	113
TIM-3: An update on immunotherapy	105
Fibroblast-like synoviocytes in rheumatoid arthritis: Surface markers and phenotypes	99
The WHO International Standard for COVID-19 serological tests: towards harmonization of anti-spike assays	98
Clinical and laboratory features of COVID-19: Predictors of severe prognosis	95
COVID-19 and cancer: From basic mechanisms to vaccine development using nanotechnology	93
Ferrostatin-1 alleviates angiotensin II (Ang II)- induced inflammation and ferroptosis in astrocytes	83
Interleukin-6 cytokine: An overview of the immune regulation, immune dysregulation, and therapeutic approach	82
Astragaloside IV promotes microglia/macrophages M2 polarization and enhances neurogenesis and angiogenesis through PPARγ pathway after cerebral ischemia/reperfusion injury in rats	81
Acute and post-acute phase of COVID-19: Analyzing expression patterns of miRNA-29a-3p, 146a-3p, 155-5p, and let-7b-3p in PBMC	79
The deregulated immune reaction and cytokines release storm (CRS) in COVID-19 disease	77
Novel serological biomarkers for inflammation in predicting disease severity in patients with COVID-19	76
A focused review on technologies, mechanisms, safety, and efficacy of available COVID-19 vaccines	72
microRNA-421-3p prevents inflammatory response in cerebral ischemia/reperfusion injury through targeting m6A Reader YTHDF1 to inhibit p65 mRNA translation	71

Luteolin inhibits autophagy in allergic asthma by activating PI3K/Akt/mTOR signaling and inhibiting Beclin-1-PI3KC3 complex	66
Immune-related adverse events associated with immune checkpoint inhibitors: An updated comprehensive disproportionality analysis of the FDA adverse event reporting system	65
Tocilizumab for treatment patients with COVID-19: Recommended medication for novel disease	64
Clostridium butyricum modulates gut microbiota and reduces colitis associated colon cancer in mice	63
Identification of immune-related lncRNA signature for predicting immune checkpoint blockade and prognosis in hepatocellular carcinoma	62
Autoimmune phenomena following SARS-CoV-2 vaccination	62
The emerging role of microRNAs in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection	62
Melatonin attenuates LPS-induced pyroptosis in acute lung injury by inhibiting NLRP3-GSDMD pathway via activating Nrf2/HO-1 signaling axis	62
Disulfidptosis classification of hepatocellular carcinoma reveals correlation with clinical prognosis and immune profile	60
The triumvirate of NF-κB, inflammation and cytokine storm in COVID-19	59
Evaluating the effects of Intravenous Immunoglobulin (IVIg) on the management of severe COVID-19 cases: A randomized controlled trial	59
The SGLT2 inhibitor empagliflozin negatively regulates IL-17/IL-23 axis-mediated inflammatory responses in T2DM with NAFLD via the AMPK/mTOR/autophagy pathway	59
Immunotherapy of Cancer by Targeting Regulatory T cells	58
Prognostic value and immunological role of PDCD1 gene in pan-cancer	58
Bacteroides thetaiotaomicron relieves colon inflammation by activating aryl hydrocarbon receptor and modulating CD4+T cell homeostasis	58
The interactions of paclitaxel with tumour microenvironment	58
Ginsenoside Rg3 attenuates angiotensin II-induced myocardial hypertrophy through repressing NLRP3 inflammasome and oxidative stress via modulating SIRT1/NF-κB pathway	57
Roles of TGF-β signaling pathway in tumor microenvirionment and cancer therapy	57
Adverse events following COVID-19 vaccination: A systematic review and meta-analysis	56
Administration of COVID-19 vaccines in immunocompromised patients	56
The Notch signaling pathway regulates macrophage polarization in liver diseases	56
The covalent NLRP3-inflammasome inhibitor Oridonin relieves myocardial infarction induced myocardial fibrosis and cardiac remodeling in mice	56
Celastrol inhibits rheumatoid arthritis through the ROS-NF-κB-NLRP3 inflammasome axis	55
Potential role of interferons in treating COVID-19 patients	55
Immunology, immunopathogenesis and immunotherapeutics of COVID-19; an overview	54
Immunotherapeutic approaches to curtail COVID-19	54
Hemoglobin, albumin, lymphocyte, and platelet (HALP) score and cancer prognosis: A systematic review and meta-analysis of 13,110 patients	54
Oncostatin M: A mysterious cytokine in cancers	53
Luteolin activates Tregs to promote IL-10 expression and alleviating caspase-11-dependent pyroptosis in sepsis-induced lung injury	53
Advance in bone destruction participated by JAK/STAT in rheumatoid arthritis and therapeutic effect of JAK/STAT inhibitors	52
Pinocembrin inhibited cardiomyocyte pyroptosis against doxorubicin-induced cardiac dysfunction via regulating Nrf2/Sirt3 signaling pathway	52
Oxygen-ozone (O2-O3) immunoceutical therapy for patients with COVID-19. Preliminary evidence reported	52
An update on colorectal cancer microenvironment, epigenetic and immunotherapy	51
Development of a macrophages-related 4-gene signature and nomogram for the overall survival prediction of hepatocellular carcinoma based on WGCNA and LASSO algorithm	51
Astragaloside IV regulates the ferroptosis signaling pathway via the Nrf2/SLC7A11/GPX4 axis to inhibit PM2.5-mediated lung injury in mice	51
Low-intensity pulsed ultrasound promotes osteoarthritic cartilage regeneration by BMSC-derived exosomes via modulating the NF-κB signaling pathway	50
Exosome-mediated miR-33 transfer induces M1 polarization in mouse macrophages and exerts antitumor effect in 4T1 breast cancer cell line	50
Breast cancer immunotherapy: Current and novel approaches	50
Synergistic cardioptotection by tilianin and syringin in diabetic cardiomyopathy involves interaction of TLR4/NF-κB/NLRP3 and PGC1a/SIRT3 pathways	50
Identification and verification of an immune-related lncRNA signature for predicting the prognosis of patients with bladder cancer	49
The impact of SGLT2 inhibitors on inflammation: A systematic review and meta-analysis of studies in rodents	49
Puerarin protects against myocardial ischemia/reperfusion injury by inhibiting inflammation and the NLRP3 inflammasome: The role of the SIRT1/NF-κB pathway	49
Mitochondrial DNA in NLRP3 inflammasome activation	49
Human umbilical cord mesenchymal stem cells-derived exosomal microRNA-17-3p ameliorates inflammatory reaction and antioxidant injury of mice with diabetic retinopathy via targeting STAT1	48
A review on evolution of emerging SARS-CoV-2 variants based on spike glycoprotein	48
Efficacy of IVIG (intravenous immunoglobulin) for corona virus disease 2019 (COVID-19): A meta-analysis	47
Effectiveness of corticosteroids to treat severe COVID-19: A systematic review and meta-analysis of prospective studies	47
Increased LPS levels coexist with systemic inflammation and result in monocyte activation in severe COVID-19 patients	47
Baicalin protects LPS-induced blood–brain barrier damage and activates Nrf2-mediated antioxidant stress pathway	47
Tetrahydroxy stilbene glycoside ameliorates Alzheimer’s disease in APP/PS1 mice via glutathione peroxidase related ferroptosis	47

LncRNA-Meg3 promotes Nlrp3-mediated microglial inflammation by targeting miR-7a-5p	47
Safety and efficacy of Favipiravir in moderate to severe SARS-CoV-2 pneumonia	46
The potential for Lactoferrin to reduce SARS-CoV-2 induced cytokine storm	46
Nanoparticles of resveratrol attenuates oxidative stress and inflammation after ischemic stroke in rats	46
LncRNA MIAT correlates with immune infiltrates and drug reactions in hepatocellular carcinoma	46
Advanced glycation end products (AGEs) and its receptor, RAGE, modulate age-dependent COVID-19 morbidity and mortality. A review and hypothesis	46
Decursin alleviates the aggravation of osteoarthritis via inhibiting PI3K-Akt and NF-kB signal pathway	45
6-Gingerol protects against cerebral ischemia/reperfusion injury by inhibiting NLRP3 inflammasome and apoptosis via TRPV1 / FAF1 complex dissociation-mediated autophagy	45
The role of IL-17 and anti-IL-17 agents in the immunopathogenesis and management of autoimmune and inflammatory diseases	45
The therapeutic potential of resveratrol in a mouse model of melanoma lung metastasis	45
Inhibition of miR-155 alleviates sepsis-induced inflammation and intestinal barrier dysfunction by inactivating NF-κB signaling	45
Drug repurposing and cytokine management in response to COVID-19: A review	45
Mitochondria-derived reactive oxygen species are involved in renal cell ferroptosis during lipopolysaccharide-induced acute kidney injury	44
Diagnostic utility of C-reactive protein to albumin ratio as an early warning sign in hospitalized severe COVID-19 patients	44
Anti-inflammatory effects of natural flavonoid diosmetin in IL-4 and LPS-induced macrophage activation and atopic dermatitis model	44
The selective STING inhibitor H-151 preserves myocardial function and ameliorates cardiac fibrosis in murine myocardial infarction	44
Intranasal delivery of MSC-derived exosomes attenuates allergic asthma via expanding IL-10 producing lung interstitial macrophages in mice	44
Emodin attenuates silica-induced lung injury by inhibition of inflammation, apoptosis and epithelial-mesenchymal transition	43
Acute kidney injury and renal replacement therapy in COVID-19 patients: A systematic review and meta-analysis	43
Application of extracellular vesicles derived from mesenchymal stem cells as potential therapeutic tools in autoimmune and rheumatic diseases	43
Update on the effectiveness of COVID-19 vaccines on different variants of SARS-CoV-2	43
Loganin alleviates sepsis-induced acute lung injury by regulating macrophage polarization and inhibiting NLRP3 inflammasome activation	43
Antibiotic administration shortly before or after immunotherapy initiation is correlated with poor prognosis in solid cancer patients: An up-to-date systematic review and meta-analysis	42
Melatonin suppresses ferroptosis via activation of the Nrf2/HO-1 signaling pathway in the mouse model of sepsis-induced acute kidney injury	42
A possible pathogenic role of Syndecan-1 in the pathogenesis of coronavirus disease 2019 (COVID-19)	42
Up-regulating lncRNA OIP5-AS1 protects neuron injury against cerebral hypoxia-ischemia induced inflammation and oxidative stress in microglia/macrophage through activating CTRP3 via sponging miR-186-5	42
SIRT1 alleviates IL-1β induced nucleus pulposus cells pyroptosis via mitophagy in intervertebral disc degeneration	42
Selective Inhibition of NLRP3 Inflammasome Reverses Pressure Overload-Induced Pathological Cardiac Remodeling by Attenuating Hypertrophy, Fibrosis, and Inflammation	41
Ginsenoside Rd attenuates cerebral ischemia/reperfusion injury by exerting an anti-pyroptotic effect via the miR-139-5p/FoxO1/Keap1/Nrf2 axis	41
Coenzyme Q10 attenuates inflammation and fibrosis implicated in radiation enteropathy through suppression of NF-kB/TGF-β/MMP-9 pathways	41
Interleukin-17 induces pyroptosis in osteoblasts through the NLRP3 inflammasome pathway in vitro	41
A novel era of cancer/testis antigen in cancer immunotherapy	41
Interleukin-2 therapy of cancer-clinical perspectives	41
Development and validation of a novel ferroptosis-related gene signature for predicting prognosis and immune microenvironment in head and neck squamous cell carcinoma	41
Resveratrol for targeting the tumor microenvironment and its interactions with cancer cells	41
Intranasal administration of small extracellular vesicles derived from mesenchymal stem cells ameliorated the experimental autoimmune encephalomyelitis	41
Resveratrol protects intestinal integrity, alleviates intestinal inflammation and oxidative stress by modulating AhR/Nrf2 pathways in weaned piglets challenged with diquat	40
Liproxstatin-1 alleviates LPS/IL-13-induced bronchial epithelial cell injury and neutrophilic asthma in mice by inhibiting ferroptosis	40
Interleukin-1 in obesity-related low-grade inflammation: From molecular mechanisms to therapeutic strategies	40
Clinical characteristics and antibiotics treatment in suspected bacterial infection patients with COVID-19	40
Echinacea polysaccharide alleviates LPS-induced lung injury via inhibiting inflammation, apoptosis and activation of the TLR4/NF-κB signal pathway	40
Curcumin protects against cognitive impairments in a rat model of chronic cerebral hypoperfusion combined with diabetes mellitus by suppressing neuroinflammation, apoptosis, and pyroptosis	39
Exosomal microRNA-98-5p from hypoxic bone marrow mesenchymal stem cells inhibits myocardial ischemia–reperfusion injury by reducing TLR4 and activating the PI3K/Akt signaling pathway	39
Juglone regulates gut microbiota and Th17/Treg balance in DSS-induced ulcerative colitis	39
The role of probiotics in coronavirus disease-19 infection in Wuhan: A retrospective study of 311 severe patients	39
Polysaccharide of Atractylodes macrocephala Koidz regulates LPS-mediated mouse hepatitis through the TLR4-MyD88-NFκB signaling pathway	39
The role of Th17 cells in viral infections	39
Patients with systemic lupus erythematosus face a high risk of cardiovascular disease: A systematic review and Meta-analysis	39
Quercetin amelioratesAspergillus fumigatuskeratitis by inhibiting fungal growth, toll-like receptors and inflammatory cytokines	38
Safety and efficacy of pembrolizumab plus lenvatinib versus pembrolizumab and lenvatinib monotherapies in cancers: A systematic review	38
Inhibitory Effect of Quercetin on Propionibacterium acnes-induced Skin Inflammation	38
Anti-inflammatory effects of Platycodin D on dextran sulfate sodium (DSS) induced colitis and E. coli Lipopolysaccharide (LPS) induced inflammation	38
Modifications of gut microbiota are associated with the severity of IgA nephropathy in the Chinese population	38
Mesenchymal stromal/stem cells and their exosomes application in the treatment of intervertebral disc disease: A promising frontier	38
Sarcopenia affects clinical efficacy of immune checkpoint inhibitors in non-small cell lung cancer patients: A systematic review and meta-analysis	37
Alpinetin exerts anti-inflammatory, anti-oxidative and anti-angiogenic effects through activating the Nrf2 pathway and inhibiting NLRP3 pathway in carbon tetrachloride-induced liver fibrosis	37
Mometasone furoate nasal spray in the treatment of patients with COVID-19 olfactory dysfunction: A randomized, double blind clinical trial	37
miR-193a-5p as a promising therapeutic candidate in colorectal cancer by reducing 5-FU and Oxaliplatin chemoresistance by targeting CXCR4	37
Pravastatin attenuates sepsis-induced acute lung injury through decreasing pulmonary microvascular permeability via inhibition of Cav-1/eNOS pathway	37
MCC950 in the treatment of NLRP3-mediated inflammatory diseases: Latest evidence and therapeutic outcomes	36
Isoliquiritin apioside relieves intestinal ischemia/reperfusion-induced acute lung injury by blocking Hif-1α-mediated ferroptosis	36
Efficacy of the omega-3 fatty acids supplementation on inflammatory biomarkers: An umbrella meta-analysis	36
Resolvin D1 mitigates non-alcoholic steatohepatitis by suppressing the TLR4-MyD88‐mediated NF‐κB and MAPK pathways and activating the Nrf2 pathway in mice	36
An update review of globally reported SARS-CoV-2 vaccines in preclinical and clinical stages	36
An updated overview of recent advances, challenges, and clinical considerations of IL-6 signaling blockade in severe coronavirus disease 2019 (COVID-19)	36
Matrine protects against DSS-induced murine colitis by improving gut barrier integrity, inhibiting the PPAR-α signaling pathway, and modulating gut microbiota	36
Promising effects of tocilizumab in COVID-19: A non-controlled, prospective clinical trial	36
Exosomes secreted by M2 macrophages promote cancer stemness of hepatocellular carcinoma via the miR-27a-3p/TXNIP pathways	36
Improved wound healing of diabetic foot ulcers using human placenta-derived mesenchymal stem cells in gelatin electrospun nanofibrous scaffolds plus a platelet-rich plasma gel: A randomized clinical t	36
MicroRNA-155 and antiviral immune responses	36
Honokiol alleviates ulcerative colitis by targeting PPAR-γ–TLR4–NF-κB signaling and suppressing gasdermin-D-mediated pyroptosis in vivo and in vitro	35
Prevalence of COVID-19 vaccines (Sputnik V, AZD-1222, and Covaxin) side effects among healthcare workers in Birjand city, Iran	35
Galangin ameliorates Imiquimod-Induced psoriasis-like skin inflammation in BALB/c mice via down regulating NF-κB and activation of Nrf2 signaling pathways	35
The role of IL-10 in kidney disease	35
Convalescent plasma may be a possible treatment for COVID-19: A systematic review	35
Cathepsin B aggravates acute pancreatitis by activating the NLRP3 inflammasome and promoting the caspase-1-induced pyroptosis	35
Oxidative stress and inflammatory markers in patients with COVID-19: Potential role of RAGE, HMGB1, GFAP and COX-2 in disease severity	35
ManNAc protects against podocyte pyroptosis via inhibiting mitochondrial damage and ROS/NLRP3 signaling pathway in diabetic kidney injury model	35
Trophoblast-derived IL-6 serves as an important factor for normal pregnancy by activating Stat3-mediated M2 macrophages polarization	35
Apatinib enhanced anti-PD-1 therapy for colon cancer in mice via promoting PD-L1 expression	35

Tetrahydropalmatine attenuates MSU crystal-induced gouty arthritis by inhibiting ROS-mediated NLRP3 inflammasome activation	35
Crosstalk between hepatic stellate cells and surrounding cells in hepatic fibrosis	34
Understanding the complexities of SARS-CoV2 infection and its immunology: A road to immune-based therapeutics	34
LncRNA SNHG7 alleviates IL-1β-induced osteoarthritis by inhibiting miR-214-5p-mediated PPARGC1B signaling pathways	34
Therapeutic vaccines for colorectal cancer: The progress and future prospect	34
Empagliflozin, a sodium glucose cotransporter-2 inhibitor, ameliorates peritoneal fibrosis via suppressing TGF-β/Smad signaling	34
Therapeutic potential of bicyclol in liver diseases: Lessons from a synthetic drug based on herbal derivative in traditional Chinese medicine	34
E484K and N501Y SARS-CoV 2 spike mutants Increase ACE2 recognition but reduce affinity for neutralizing antibody	34
Potential benefits of patchouli alcohol in prevention of human diseases: A mechanistic review	34
Serum glial fibrillary acidic protein is a body fluid biomarker: A valuable prognostic for neurological disease – A systematic review	34
Dehydrocostus lactone inhibits BLM-induced pulmonary fibrosis and inflammation in mice via the JNK and p38 MAPK-mediated NF-κB signaling pathways	34
Chemokine CXCL14; a double-edged sword in cancer development	34
PD-1/PD-L1 enhanced cisplatin resistance in gastric cancer through PI3K/AKT mediated P-gp expression	34
Baicalin protects against zearalenone-induced chicks liver and kidney injury by inhibiting expression of oxidative stress, inflammatory cytokines and caspase signaling pathway	34
Hypoxia and Porphyromonas gingivalis-lipopolysaccharide synergistically induce NLRP3 inflammasome activation in human gingival fibroblasts	33
Targeting macrophage polarization as a promising therapeutic strategy for the treatment of osteoarthritis	33
RETRACTED: BMSCs-derived exosomal microRNA-150-5p attenuates myocardial infarction in mice	33
Role of glucose metabolism in aggressive phenotype of fibroblast-like synoviocytes: Latest evidence and therapeutic approaches in rheumatoid arthritis	33
Cytokine imbalance at materno-embryonic interface as a potential immune mechanism for recurrent pregnancy loss	33
Apelin/APJ system in inflammation	33
HIF-1α activator DMOG inhibits alveolar bone resorption in murine periodontitis by regulating macrophage polarization	33
Role of CCL2/CCR2 axis in the pathogenesis of COVID-19 and possible Treatments: All options on the Table	33
Persistence of SARS-CoV-2-specific antibodies in COVID-19 patients	33
Auraptene exerts protective effects on maternal separation stress-induced changes in behavior, hippocampus, heart and serum of mice	33
Canagliflozin alleviates LPS-induced acute lung injury by modulating alveolar macrophage polarization	33
Biological effects of IL-15 on immune cells and its potential for the treatment of cancer	33
Aggravation of autism-like behavior in BTBR T+tf/J mice by environmental pollutant, di-(2-ethylhexyl) phthalate: Role of nuclear factor erythroid 2-related factor 2 and oxidative enzymes in innate imm	33
The effectiveness of blood routine parameters and some biomarkers as a potential diagnostic tool in the diagnosis and prognosis of Covid-19 disease	33
Auranofin: Past to Present, and repurposing	33
Phenylalanine and COVID-19: Tracking disease severity markers	33
miR-129-5p alleviates LPS-induced acute kidney injury via targeting HMGB1/TLRs/NF-kappaB pathway	32
Crocetin attenuates the oxidative stress, inflammation and apoptosis in arsenic trioxide-induced nephrotoxic rats: Implication of PI3K/AKT pathway	32
Liensinine alleviates high fat diet (HFD)-induced non-alcoholic fatty liver disease (NAFLD) through suppressing oxidative stress and inflammation via regulating TAK1/AMPK signaling	32
Crosstalk between Wnt/β-catenin signaling and NF-κB signaling contributes to apical periodontitis	32
Molecular mimicry, hyperactive immune system, and SARS-COV-2 are three prerequisites of the autoimmune disease triangle following COVID-19 infection	32
NLRP3 inflammasome inhibitor INF39 attenuated NLRP3 assembly in macrophages	32
Thymosin α1 therapy in critically ill patients with COVID-19: A multicenter retrospective cohort study	32
Crosstalk between the gut microbiota and postmenopausal osteoporosis: Mechanisms and applications	32
Natural shikonin and acetyl-shikonin improve intestinal microbial and protein composition to alleviate colitis-associated colorectal cancer	32
Prediction and analysis of microRNAs involved in COVID-19 inflammatory processes associated with the NF-kB and JAK/STAT signaling pathways	32
Inactivated SARS-CoV-2 vaccines elicit immunogenicity and T-cell responses in people living with HIV	32
Rituximab exhibits a better safety profile when used as a first line of treatment for pemphigus vulgaris: A retrospective study	32
What is the impact and efficacy of routine immunological, biochemical and hematological biomarkers as predictors of COVID-19 mortality?	32
Continuous tracking of COVID-19 patients' immune status	32
Melatonin-mediated MT2 attenuates colitis induced by dextran sodium sulfate via PI3K/AKT/Nrf2/SIRT1/RORα/NF-κB signaling pathways	31
Drug-induced pemphigus: A systematic review of 170 patients	31
The role of vitamin D in reducing SARS-CoV-2 infection: An update	31
Interferon-inducer antivirals: Potential candidates to combat COVID-19	31
Cigarette smoke extract-treated airway epithelial cells-derived exosomes promote M1 macrophage polarization in chronic obstructive pulmonary disease	31
Alpinetin prevents inflammatory responses in OVA-induced allergic asthma through modulating PI3K/AKT/NF-κB and HO-1 signaling pathways in mice	31
Immunotherapy of inflammatory bowel disease (IBD) through mesenchymal stem cells	31
SARS-CoV-2: Insight in genome structure, pathogenesis and viral receptor binding analysis – An updated review	31
Bixin attenuates carbon tetrachloride induced oxidative stress, inflammation and fibrosis in kidney by regulating the Nrf2/TLR4/MyD88 and PPAR-γ/TGF-β1/Smad3 pathway	31
Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options	31
Epigallocatechin-3-gallate prevents inflammation and diabetes -Induced glucose tolerance through inhibition of NLRP3 inflammasome activation	31
Platelets in the perspective of COVID-19; pathophysiology of thrombocytopenia and its implication as prognostic and therapeutic opportunity	31
Bruton’s tyrosine kinase inhibition attenuates oxidative stress in systemic immune cells and renal compartment during sepsis-induced acute kidney injury in mice	31
Astrocyte-derived CCL7 promotes microglia-mediated inflammation following traumatic brain injury	31
The immune response and immune evasion characteristics in SARS-CoV, MERS-CoV, and SARS-CoV-2: Vaccine design strategies	31
Anti-inflammatory effect of phenylpropanoids from Dendropanax dentiger in TNF-α-induced MH7A cells via inhibition of NF-κB, Akt and JNK signaling pathways	31
Tumor-associated macrophages-mediated CXCL8 infiltration enhances breast cancer metastasis: Suppression by Danirixin	30
UUO induces lung fibrosis with macrophage-myofibroblast transition in rats	30
Targeting the PD-1/PD-L1 pathway in glioblastoma multiforme: Preclinical evidence and clinical interventions	30
Construction of an immune-related gene signature for prediction of prognosis in patients with cervical cancer	30
Immunomodulatory effects of a polysaccharide from Solanum nigrum Linne through TLR4-MyD88 signaling pathway	30
Current evidence on the use of anakinra in COVID-19	30
Virucidal activity of Moringa A from Moringa oleifera seeds against Influenza A Viruses by regulating TFEB	30
Coronavirus disease 2019 (COVID-19): Immunological approaches and emerging pharmacologic treatments	30
Flavonoids, the compounds with anti-inflammatory and immunomodulatory properties, as promising tools in multiple sclerosis (MS) therapy: A systematic review of preclinical evidence	30
LCZ696 protects against doxorubicin-induced cardiotoxicity by inhibiting ferroptosis via AKT/SIRT3/SOD2 signaling pathway activation	30
SIRT6 inhibits inflammatory response through regulation of NRF2 in vascular endothelial cells	30
Favipiravir in the treatment of patients with SARS-CoV-2 RNA recurrent positive after discharge: A multicenter, open-label, randomized trial	30
Protective effects of Salvianolic acid B on rat ferroptosis in myocardial infarction through upregulating the Nrf2 signaling pathway	30
Platelet-rich plasma-derived exosomes attenuate intervertebral disc degeneration by promoting NLRP3 autophagic degradation in macrophages	30
Leflunomide an immunomodulator with antineoplastic and antiviral potentials but drug-induced liver injury: A comprehensive review	29
Resveratrol inhibits MRGPRX2-mediated mast cell activation via Nrf2 pathway	29
Pathogenesis of Concanavalin A induced autoimmune hepatitis in mice	29
Carnosine alleviates podocyte injury in diabetic nephropathy by targeting caspase-1-mediated pyroptosis	29
Pan-cancer analysis reveals the expression, genetic alteration and prognosis of pyroptosis key gene GSDMD	29
Fluoxetine ameliorates Alzheimer’s disease progression and prevents the exacerbation of cardiovascular dysfunction of socially isolated depressed rats through activation of Nrf2/HO-1 and hindering TLR	29
Dioscin prevents DSS-induced colitis in mice with enhancing intestinal barrier function and reducing colon inflammation	29
Cordycepin attenuates high-fat diet-induced non-alcoholic fatty liver disease via down-regulation of lipid metabolism and inflammatory responses	29
Syringin exerts neuroprotective effects in a rat model of cerebral ischemia through the FOXO3a/NF-κB pathway	29
Baicalin alleviates Mycoplasma gallisepticum-induced oxidative stress and inflammation via modulating NLRP3 inflammasome-autophagy pathway	29
SGLT2 inhibitor, canagliflozin, ameliorates cardiac inflammation in experimental autoimmune myocarditis	29
Gut microbiome and multiple sclerosis: New insights and perspective	29
Didymin ameliorates dexamethasone-induced non-alcoholic fatty liver disease by inhibiting TLR4/NF-κB and PI3K/Akt pathways in C57BL/6J mice	29
The role of interleukin-10 family members in cardiovascular diseases	29
Oxymatrine inhibits neuroinflammation by Regulating M1/M2 polarization in N9 microglia through the TLR4/NF-κB pathway	29
The immunomodulatory mechanism of dexmedetomidine	29
Identification of DRP1 as a prognostic factor correlated with immune infiltration in breast cancer	29
Crosstalk between macrophages and natural killer cells in the tumor microenvironment	29
Anti-inflammatory effects of B vitamins protect against tau hyperphosphorylation and cognitive impairment induced by 1,2 diacetyl benzene: An in vitro and in silico study	28
Neuroinflammation in hemorrhagic transformation after tissue plasminogen activator thrombolysis: Potential mechanisms, targets, therapeutic drugs and biomarkers	28
Forsythoside B attenuates neuro-inflammation and neuronal apoptosis by inhibition of NF-κB and p38-MAPK signaling pathways through activating Nrf2 post spinal cord injury	28