OOIR: Observatory of International Research

Papers

(The H4-Index of International Immunopharmacology is 53. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
MCP-1: Function, regulation, and involvement in disease	378
COVID-19 vaccine hesitancy and related fears and anxiety	251
Effect of gut microbiota on LPS-induced acute lung injury by regulating the TLR4/NF-kB signaling pathway	238
Anti-inflammatory and M2 macrophage polarization-promoting effect of mesenchymal stem cell-derived exosomes	211
Effects of immune cells and cytokines on inflammation and immunosuppression in the tumor microenvironment	200
Nano-curcumin therapy, a promising method in modulating inflammatory cytokines in COVID-19 patients	190
Interferon β-1b in treatment of severe COVID-19: A randomized clinical trial	141
Neutrophils and COVID-19: The road so far	126
Toll-like receptors in sepsis-associated cytokine storm and their endogenous negative regulators as future immunomodulatory targets	124
The roles of macrophage polarization in the host immune response to sepsis	117
Neutrophil Extracellular Traps (NETs) and Covid-19: A new frontiers for therapeutic modality	114
Dimethyl fumarate improves cognitive deficits in chronic cerebral hypoperfusion rats by alleviating inflammation, oxidative stress, and ferroptosis via NRF2/ARE/NF-κB signal pathway	113
TIM-3: An update on immunotherapy	105
Fibroblast-like synoviocytes in rheumatoid arthritis: Surface markers and phenotypes	99
The WHO International Standard for COVID-19 serological tests: towards harmonization of anti-spike assays	98
Clinical and laboratory features of COVID-19: Predictors of severe prognosis	95
COVID-19 and cancer: From basic mechanisms to vaccine development using nanotechnology	93
Ferrostatin-1 alleviates angiotensin II (Ang II)- induced inflammation and ferroptosis in astrocytes	83
Interleukin-6 cytokine: An overview of the immune regulation, immune dysregulation, and therapeutic approach	82
Astragaloside IV promotes microglia/macrophages M2 polarization and enhances neurogenesis and angiogenesis through PPARγ pathway after cerebral ischemia/reperfusion injury in rats	81
Acute and post-acute phase of COVID-19: Analyzing expression patterns of miRNA-29a-3p, 146a-3p, 155-5p, and let-7b-3p in PBMC	79
The deregulated immune reaction and cytokines release storm (CRS) in COVID-19 disease	77
Novel serological biomarkers for inflammation in predicting disease severity in patients with COVID-19	76
A focused review on technologies, mechanisms, safety, and efficacy of available COVID-19 vaccines	72
microRNA-421-3p prevents inflammatory response in cerebral ischemia/reperfusion injury through targeting m6A Reader YTHDF1 to inhibit p65 mRNA translation	71

Luteolin inhibits autophagy in allergic asthma by activating PI3K/Akt/mTOR signaling and inhibiting Beclin-1-PI3KC3 complex	66
Immune-related adverse events associated with immune checkpoint inhibitors: An updated comprehensive disproportionality analysis of the FDA adverse event reporting system	65
Tocilizumab for treatment patients with COVID-19: Recommended medication for novel disease	64
Clostridium butyricum modulates gut microbiota and reduces colitis associated colon cancer in mice	63
The emerging role of microRNAs in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection	62
Melatonin attenuates LPS-induced pyroptosis in acute lung injury by inhibiting NLRP3-GSDMD pathway via activating Nrf2/HO-1 signaling axis	62
Identification of immune-related lncRNA signature for predicting immune checkpoint blockade and prognosis in hepatocellular carcinoma	62
Autoimmune phenomena following SARS-CoV-2 vaccination	62
Disulfidptosis classification of hepatocellular carcinoma reveals correlation with clinical prognosis and immune profile	60
Evaluating the effects of Intravenous Immunoglobulin (IVIg) on the management of severe COVID-19 cases: A randomized controlled trial	59
The SGLT2 inhibitor empagliflozin negatively regulates IL-17/IL-23 axis-mediated inflammatory responses in T2DM with NAFLD via the AMPK/mTOR/autophagy pathway	59
The triumvirate of NF-κB, inflammation and cytokine storm in COVID-19	59
Prognostic value and immunological role of PDCD1 gene in pan-cancer	58
Bacteroides thetaiotaomicron relieves colon inflammation by activating aryl hydrocarbon receptor and modulating CD4+T cell homeostasis	58
The interactions of paclitaxel with tumour microenvironment	58
Immunotherapy of Cancer by Targeting Regulatory T cells	58
Roles of TGF-β signaling pathway in tumor microenvirionment and cancer therapy	57
Ginsenoside Rg3 attenuates angiotensin II-induced myocardial hypertrophy through repressing NLRP3 inflammasome and oxidative stress via modulating SIRT1/NF-κB pathway	57
Administration of COVID-19 vaccines in immunocompromised patients	56
The Notch signaling pathway regulates macrophage polarization in liver diseases	56
The covalent NLRP3-inflammasome inhibitor Oridonin relieves myocardial infarction induced myocardial fibrosis and cardiac remodeling in mice	56
Adverse events following COVID-19 vaccination: A systematic review and meta-analysis	56
Potential role of interferons in treating COVID-19 patients	55
Celastrol inhibits rheumatoid arthritis through the ROS-NF-κB-NLRP3 inflammasome axis	55
Immunotherapeutic approaches to curtail COVID-19	54
Hemoglobin, albumin, lymphocyte, and platelet (HALP) score and cancer prognosis: A systematic review and meta-analysis of 13,110 patients	54
Immunology, immunopathogenesis and immunotherapeutics of COVID-19; an overview	54
Luteolin activates Tregs to promote IL-10 expression and alleviating caspase-11-dependent pyroptosis in sepsis-induced lung injury	53
Oncostatin M: A mysterious cytokine in cancers	53