OOIR: Observatory of International Research

Papers

(The median citation count of Current Neurovascular Research is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Severe Acute Respiratory Syndrome Coronavirus 2 is Penetrating to Dementia Research	27
Curcumin Alleviates Cerebral Ischemia-reperfusion Injury by Inhibiting NLRP1-dependent Neuronal Pyroptosis	26
Serum Albumin as a Potential Predictor of Pneumonia after an Acute Ischemic Stroke	18
Penumbra in Acute Ischemic Stroke	16
Combination of Peroxisome Proliferator-activated Receptor Gamma (PPARγ) Agonist and PPAR Gamma Co-Activator 1α (PGC-1α) Activator Ameliorates Cognitive Deficits, Oxidative Stress, and Inflammation in	15
Interleukin-6: Important Mediator of Vasospasm Following Subarachnoid Hemorrhage	14
Platelet-to-neutrophil Ratio after Intravenous Thrombolysis Predicts Unfavorable Outcomes in Acute Ischemic Stroke	12
Dietary Phytoestrogens: Neuroprotective Role in Parkinson’s Disease	12
LncRNA SNHG12 Improves Cerebral Ischemic-reperfusion Injury by Activating SIRT1/FOXO3a Pathway through I nhibition of Autophagy and Oxidative Stress	12
The Angiogenesis Effects of Electro-acupuncture Treatment via Exosomal miR-210 in Cerebral Ischemia-Reperfusion Rats	11
Hydroxysafflor Yellow a Promotes Angiogenesis in Rat Brain Microvascular Endothelial Cells Injured by Oxygen-glucose Deprivation/reoxygenation(OGD/R) through SIRT1-HIF-1α-VEGFA Signaling Pathway	11
Anti-Inflammatory Effect of Ginsenoside Rg1 on LPS-Induced Septic Encephalopathy and Associated Mechanism	11
The Metabolic Basis for Nervous System Dysfunction in Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease	10
Protective Effect of GSK-3β/Nrf2 Mediated by Dimethyl Fumarate in Middle Cerebral Artery Embolization Reperfusion Rat Model	10
The Interplay Among Epilepsy, Parkinson’s Disease and Inflammation: Revisiting the Link through Ca2+/cAMP Signalling	9
The Role of Thrombo-inflammatory Biomarkers in the Prognosis of Cerebral Venous Sinus Thrombosis	9
Acute Ischaemic Stroke Incidence after Coronavirus Vaccine in Indonesia: Case Series	9
Propofol Protects Against TNF-α-induced Blood-brain Barrier Disruption via the PIM-1/eNOS/NO Pathway	8
Serum Interleukin-33 is a Predictor of Depression in Patients with Acute Ischemic Stroke	8
Brivaracetam Prevents the Over-expression of Synaptic Vesicle Protein 2A and Rescues the Deficits of Hippocampal Long-term Potentiation In Vivo in Chronic Temporal Lobe Epilepsy Rats	8
U-Shaped Association Between Serum Uric Acid and Hemorrhagic Transformation After Intravenous Thrombolysis	7
Apolipoprotein-ε4 allele (APOE-ε4) as a Mediator of Cognitive Loss and Dementia in Long COVID-19	7
Stroke History is an Independent Risk Factor for Poor Prognosis in Ischemic Stroke Patients: Results from a Large Nationwide Stroke Registry	7
Association Between Cardiometabolic Index and Stroke: A Population- based Cross-sectional Study	7
Circulating miR-126 as a Potential Non-invasive Biomarker for Intracranial Aneurysmal Rupture: A Pilot Study	7

Novel Insights for Multiple Sclerosis and Demyelinating Disorders with Apoptosis, Autophagy, FoxO, and mTOR	7
Association of High-sensitivity C-reactive Protein with Patient Prognosis Following Mechanical Thrombectomy for Acute Ischemic Stroke	7
Association Between Coagulation Function and Spontaneous Hemorrhagic Transformation in Acute Ischemic Stroke	7
Estrogen Receptor 1 Gene rs22346939 and rs9340799 Variants are Associated with Major Depressive Disorder and its Clinical Features	7
Electroacupuncture Inhibits Ferroptosis Induced by Cerebral Ischemiareperfusion	7
NEP1-40-overexpressing Neural Stem Cells Enhance Axon Regeneration by Inhibiting Nogo-A/NgR1 Signaling Pathway	6
Choroidal Changes in Carotid Stenosis Patients After Stenting Detected by Swept-source Optical Coherence Tomography Angiography	6
Propofol Rescued Astrocytes from LPS-induced Inflammatory Response via Blocking LncRNA-MEG3/NF-κB Axis	6
MiR-582-5p Attenuates Neonatal Hypoxic-ischemic Encephalopathy by Targeting High Mobility Group box 1 (HMGB1) through Inhibiting Neuroinflammation and Oxidative Stress	6
Human Olfactory Ensheathing Cell-derived Extracellular Cesicles: miRNA Profile and Neuroprotective Effect	6
Association of Variants in FCGR2A, PTPN2, and GM-CSF with Cerebral Cavernous Malformation: Potential Biomarkers for a Symptomatic Disease	6
Diindolylmethane Ameliorates Ischemic Stroke-Induced Brain Injury by Peripheral and Central Mechanisms	6
Haptoglobin Genotype Affects Inflammation after Aneurysmal Subarachnoid Hemorrhage	6
Nomogram to Predict Symptomatic Intracranial Hemorrhage after Intravenous Thrombolysis in Acute Ischemic Stroke in Asian Population	6
Assessment of White Matter Lesions in Parkinson's Disease: Voxel-based Analysis and Tract-based Spatial Statistics Analysis of Parkinson's Disease with Mild Cognitive Impairment	6
Association Between Serum Lipid Levels and Severe Headache or Migraine in Representative American Population: A Cross-sectional Study	6
Microbleeds after Stent-assisted Coil Embolization of Unruptured Intracranial Aneurysms: Incidence, Risk Factors and the Role of Thromboelastography	6
CORM-3 Regulates Microglia Activity, Prevents Neuronal Injury, and Improves Memory Function During Radiation-induced Brain Injury	6
Addressing Alzheimer’s Disease and Cognitive Loss through Autophagy	6
Hippocampal miR-124 Participates in the Pathogenesis of Depression via Regulating the Expression of BDNF in a Chronic Social Defeat Stress Model of Depression	6
Association Between Systemic Immune-Inflammation Index and Symptomatic Intracranial Hemorrhage in Acute Ischemic Stroke Patients Undergoing Endovascular Treatment	6
Higher Levels of Dynamin-related Protein 1 are Associated with Reduced Radiation Sensitivity of Glioblastoma Cells	6
Anti-vascular Endothelial Growth Factor Antibody Limits the Vascular Leakage and Decreases Subretinal Fibrosis in a Cynomolgus Monkey Choroidal Neovascularization Model	6
Biomarkers for Parkinson’s Disease and Neurodegenerative Disorders: A Role for Non-coding RNAs	6
Metformin Ameliorates Neuronal Necroptosis after Intracerebral Hemorrhage by Activating AMPK	5
Landmark-Based Shape Analysis on Middle Cerebral Intracranial Aneurysms: A Geometric Morphometrics Approach to Infer Natural History	5
Pan-Immune-Inflammatory Value Predicts the 3 Months Outcome in Acute Ischemic Stroke Patients after Intravenous Thrombolysis	5
APOE4: A Culprit for the Vulnerability of COVID-19 in Alzheimer's Patients	5
Malnutrition could Predict 3-month Functional Prognosis in Mild Stroke Patients: Findings from a Nationwide Stroke Registry	5
The Implications of Telomere Length: Advanced Aging, Cell Senescence, MRI Phenotypes, Stem Cells and Alzheimer’s Disease	5
Regulatory mechanism of the SNHG3/miR-302a-3p/E2F1 feedback loop in nerve repair post cerebral ischemic stroke	5
Pyroptosis, Apoptosis, and Autophagy: Critical Players of Inflammation and Cell Demise in the Nervous System	5
Guanabenz and Clonidine, α2-Adrenergic Receptor Agonists, Inhibit Choroidal Neovascularization	5
Cerium Oxide Nanoparticles Ameliorate Oxidative Stress, Inflammation, and Pain Behavior in Neuropathic Rats	5
Sleep Disorders, Neurodegeneration, Glymphatic Pathways, and Circadian Rhythm Disruption	5
Association Between Neutrophil to Lymphocyte Ratio and Malignant Brain Edema in Patients With Large Hemispheric Infarction	5
miR-666-3p Mediates the Protective Effects of Mesenchymal Stem Cell-derived Exosomes Against Oxygen-glucose Deprivation and Reoxygenation-induced Cell Injury in Brain Microvascular Endothelial Cells v	5
Impact of Endothelial NOS VNTR Variant on Susceptibility to Diabetic Neuropathy and Type 2 Diabetes Mellitus	5
Association of Serum Interleukin-34 and Insulin Resistance with Cognitive Impairment in Patients with Cerebral Small Vessel Disease	5
Protective Effects of Icariin on Traumatic Brain Injury	4
Alcohol Drinking, Apolipoprotein Polymorphisms and the Risk of Cardiovascular Diseases	4
A Non-Peptidic MAS1 Agonist AVE0991 Alleviates Hippocampal Synaptic Degeneration in Rats with Chronic Cerebral Hypoperfusion	4
Perfusion Deficits in Different Mechanisms of Two Subtypes of Acute Stroke with Diffusion MRI Confirmation	4
The Oversight of Circadian Clock Genes for the Detection, Prevention, and Treatment of COVID-19 Infection	4
The Role of Serum Secretoneurin Levels in Patients with Traumatic Brain Injury	4
Plasma Retinol Binding Protein 4 as a Biomarker for Detecting Progressive Stroke and Prediction of Early Prognosis in Patients with Acute Ischemic Stroke	4
Irregular Baseline Brain Activity in Coronary Artery Disease Patients with Cognitive Impairment: A Resting-state Functional Magnetic Resonance Imaging Study	4
A Novel Nomogram for Predicting Prognosis after Mechanical Thrombectomy in Patients with Acute Ischemic Stroke	4
Alcohol Use Disorder and Dementia: Critical Mechanisms for Cognitive Loss	4
The Prognostic Significance of White Blood Cell and Platelet Count for Inhospital Mortality and Pneumonia in Acute Ischemic Stroke	4

Association of Non-Traditional Lipid Parameters with Hemorrhagic Transformation and Clinical Outcome After Thrombolysis in Ischemic Stroke Patients	4
Autophagy Inhibition Preserves Tight Junction of Human Cerebral Microvascular Endothelium Under Oxygen Glucose Deprivation	4
Association of Admission Leukocyte Count with Clinical Outcomes in Acute Ischemic Stroke Patients Undergoing Intravenous Thrombolysis with Recombinant Tissue Plasminogen Activator	4
Elevated Total Homocysteine Predicts In-Hospital Pneumonia and Poor Functional Outcomes in Acute Ischemic Stroke	4
Early Post-stroke Depressive Symptoms are Associated with Low Peripheral Levels of Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1) and Glial Cell-derived Neurotrophic Factor (GDNF)	4
Neurological Complications in COVID-19 Patients and its Implications for Associated Mortality	4
Nicotinamide as a Foundation for Treating Neurodegenerative Disease and Metabolic Disorders	4
Elevated Serum Homocysteine Associated with Distal Type of Single Small Subcortical Infarction	4
Clinical Efficacy of Functional Electrical Stimulation-assisted Rehabilitation Cycling on the Function of Lower Limbs in Patients with Stroke	4
Restoration of the Attenuated Neuroprotective Effect of Ischemic Postconditioning in Diabetic Mice by SGLT Inhibitor Phlorizin	4
Melatonin Inhibits the Malignant Progression of Glioblastoma via Regulating miR-16-5p/PIM1	3
Inflammation-based Scores are Associated with the Prognosis of Patients with Aneurysmal Subarachnoid Hemorrhage After Neuro-intervention	3
A Common Link in Neurovascular Regenerative Pathways: Protein Kinase B (Akt)	3
Correlation Between Plasma Levels of RIP3 and Acute Ischemic Stroke with Large-Artery Atherosclerosis	3
Agonism of Histaminergic-H1 Receptors in Ischemic Postconditioning During Cerebral Ischemia-Reperfusion Injury is Protective	3
DL-3-n-butylphthalide Attenuates Cerebral Ischemia-Reperfusion Injury by Inhibiting Mitochondrial Omi/HtrA2-Mediated Apoptosis	3
Ferroptosis, Iron Metabolism, and Forkhead Transcription Factors (FoxOs)	3
Efficacy and Safety of Alteplase on Treatment of Acute Single Small Subcortical Infarction	3
Sevoflurane Post-treatment Mitigates Oxygen-glucose Deprivationinduced Pyroptosis of Hippocampal Neurons by Regulating the Mafb/DUSP14 Axis	3
P75NTR Exacerbates SCI-induced Mitochondrial Damage and Neuronal Apoptosis Depending on NTRK3	3
Heme Oxygenase-1 may Mediate Early Inflammatory Response of Intracerebral Hemorrhage through Toll-like Receptor 4 Signaling Pathway	3
Early Cognitive Impairment at Acute Stage After Intracerebral Hemorrhage	3
Peripheral Neuropathy: An Early Indication of Systemic Disease that Involves the Mechanistic Target of Rapamycin (mTOR)	3
Correlation between Bispectral Index and Prognosis of Patients with Acute Cerebral Infarction	3
Wnt Signaling and WISP1 (CCN4): Critical Components in Neurovascular Disease, Blood Brain Barrier Regulation, and Cerebral Hemorrhage	3
Insights of Valacyclovir in Treatment of Alzheimer’s Disease: Computational Docking Studies and Scopolamine Rat Model	3
Curcumin Alleviates Oxidative Stress, Neuroinflammation, and Promotes Behavioral Recovery After Traumatic Brain Injury	3
Mechanism of Toll-like Receptor 4 on Chronic Post-thoracotomy Pain Via Caspase-1 Activation	3
Wheel Running Adversely Affects Disease Onset and Neuromuscular Interplay in Amyotrophic Lateral Sclerosis Slow Progression Mouse Model	3
Simvastatin Upregulates Lipoxin A4 and Accelerates Neuroinflammation Resolution After Intracerebral Hemorrhage	3
Association of Posture Instability with Dopamine Drop of Nigrostriatal System and Hypometabolism of Cerebral Cortex in Parkinson’s Disease	3
Smoking, Coffee Consumption, Alcohol Intake, and Obstructive Sleep Apnea: A Mendelian Randomization Study	3
Development of a Nomogram for Predicting Asymptomatic Coronary Artery Disease in Patients with Ischemic Stroke	2
Regulatory Effect of Electroacupuncture on Hypothalamic Serotonin and its Receptor in Rats with Cerebral Ischemia	2
Factors Related to Mechanical Thrombectomy Failure in Large Vessel Occlusion: A Propensity Score Matching Analysis	2
Dual Specificity Phosphatase 3 (DUSP3) Knockdown Alleviates Acute Myocardial Infarction Damage via Inhibiting Apoptosis and Inflammation	2
Canopy Fibroblast Growth Factor Signaling Regulator 2 (CNPY2) Inhibits Neuron Apoptosis in Parkinson’s Disease via the AKT/GSK3β Pathway	2
Low-frequency Electrical Stimulation of the Hippocampus Plays a Role in the Treatment of Pharmacoresistant Epilepsy by Blocking the PKA-CREB Pathway	2
Cognitive Impairment and Mossy Fiber Sprouting in a Rat Model of Drug-resistant Epilepsy Induced by Lithium-pilocarpine	2
Serum Levels of ARMS2, COL8A1, RAD51B, and VEGF and their Correlations in Age-related Macular Degeneration	2
Does Weekends Effect Exist in Asia? Analysis of Endovascular Thrombectomy for Acute Ischemic Stroke in A Medical Center	2
Paeonol Attenuates the Endothelial-to-Mesenchymal Transition Induced by TGF-β1 in Human Umbilical Vein Endothelial Cells through ALK5- Smad2/3 Signaling Pathway	2
Adipokines as Potential Biomarkers in the Neurorehabilitation of Obese Stroke Patients	2
Impact of Headache Frequency and Sleep on Migraine Patients During the COVID-19 Pandemic	2
Peptide5 Attenuates rtPA Related Brain Microvascular Endothelial Cells Reperfusion Injury via the Wnt/β-Catenin Signalling Pathway	2
Effect of Early Balloon Inflation of Balloon Guide Catheter in Mechanical Thrombectomy for Large Vessel Occlusion	2
Electro-acupuncture Promotes Angiogenesis via Exosomal miR-210 in the Hypoxia-induced HUVECs Mediated HIF-1α/VEGF/Notch 1 Signal Pathway	2
Analysis of Prognostic Risk Factors for Ischemic Stroke in China: A Multicentre Retrospective Clinical Study; A National Survey in China	2
Causal Effects of Blood Metabolites and Obstructive Sleep Apnea: A Mendelian Randomization Study	2
Contralateral Posterior Putaminal 18F-Fluorodopa Uptake in Mild Stage Parkinson’s Disease: A PET/CT Study	2
Microglia: Formidable Players in Alzheimer’s Disease and Other Neurodegenerative Disorders	2
Keap1 as Target of Genistein on Nrf2 Signaling Pathway Antagonizing Aβ induced Oxidative Damage of Cerebrovascular Endothelial Cells	2
Cerebral Ischemia Induces Iron Deposit, Ferritin Accumulation, Nuclear Receptor Coactivator 4-depletion, and Ferroptosis	2
Circadian Clock Genes: Targeting Innate Immunity for Antiviral Strategies Against COVID-19	2
Chronic Cerebral Hypoperfusion-induced Dysregulations of Hyperpolarization- activated Cyclic Nucleotide-gated, KCNQ and G Protein-coupled Inwardly Rectifying Potassium Channels Correlated with Suscept	2
The Effect of Acupuncture on Enteral Nutrition and Gastrointestinal Dynamics in Patients Who Have Suffered a Severe Stroke	2
Nicotinamide: Oversight of Metabolic Dysfunction Through SIRT1, mTOR, and Clock Genes	2
Genome-wide Association Studies of REST Gene Associated Neurological Diseases/traits with Related Single Nucleotide Polymorphisms	2
Caffeic Acid Phenethyl Ester (CAPE) Attenuates Paclitaxel-induced Peripheral Neuropathy: A Mechanistic Study	2
Myasthenia Gravis and Ischemic Stroke: A Bidirectional Mendelian Randomization Study	2
Prevalence and Prognostic Factors of Cortical Laminar Necrosis in Acute Ischemic Stroke	2
Electroacupuncture Pretreatment Alleviates Cerebral Ischemia-reperfusion Injury by Down-regulating Mir-155-5p	2
Major Targets Involved in Clinical Management of Migraine	2
Neutrophil-to-lymphocyte Ratio Predicts the Outcome of Cerebral Venous Thrombosis	2
Ethyl Pyruvate Alleviating Inflammatory Response after Diabetic Cerebral Hemorrhage	2
Adenosine Receptor Modulation of Hypoxic-ischemic Injury in Striatum of Newborn Piglets	2
Malignant Middle Cerebral Artery Infarction during Early versus Late Endovascular Treatment in Acute Ischemic Stroke	2