OOIR: Observatory of International Research

Papers

(The TQCC of Epigenetics is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Epigenetic mechanisms regulating COVID-19 infection	96
Genome-wide CpG density and DNA methylation analysis method (MeDIP, RRBS, and WGBS) comparisons	48
Comprehensive analysis of the transcriptome-wide m6A methylome in colorectal cancer by MeRIP sequencing	47
The Socioeconomic Gradient in Epigenetic Ageing Clocks: Evidence from the Multi-Ethnic Study of Atherosclerosis and the Health and Retirement Study	38
Saliva cell type DNA methylation reference panel for epidemiological studies in children	37
The landscape of accessible chromatin in bovine oocytes and early embryos	33
Cell-free DNA Methylation and Transcriptomic Signature Prediction of Pregnancies with Adverse Outcomes	33
Estrogen-induced epigenetic silencing of FTH1 and TFRC genes reduces liver cancer cell growth and survival	32
Major gene expression changes and epigenetic remodelling in Nile tilapia muscle after just one generation of domestication	31
The myonuclear DNA methylome in response to an acute hypertrophic stimulus	28
Fusaric acid decreases p53 expression by altering promoter methylation and m6A RNA methylation in human hepatocellular carcinoma (HepG2) cells	28
The landscape of CD28, CD80, CD86, CTLA4, and ICOS DNA methylation in head and neck squamous cell carcinomas	27
SET1/MLL family of proteins: functions beyond histone methylation	27
Epigenome-wide association study for glyphosate induced transgenerational sperm DNA methylation and histone retention epigenetic biomarkers for disease	26
Mitochondrial DNA methylation in placental tissue: a proof of concept study by means of prenatal environmental stressors	26
Genomic map of candidate human imprint control regions: the imprintome	25
Prenatal gestational diabetes mellitus exposure and accelerated offspring DNA methylation age in early childhood	25
Music-listening regulates human microRNA expression	24
DNA methylation profile of genes involved in inflammation and autoimmunity correlates with vascular function in morbidly obese adults	24
Micronutrient supplementation affects transcriptional and epigenetic regulation of lipid metabolism in a dose-dependent manner	22
Recent insights intoHistone Acetyltransferase-1: biological function and involvement in pathogenesis	21
Minimally invasive classification of paediatric solid tumours using reduced representation bisulphite sequencing of cell-free DNA: a proof-of-principle study	21
DNA methylation in promoter regions of genes involved in the reproductive and metabolic function of children born to women with PCOS	21
Associations between maternal lifetime stressors and negative events in pregnancy and breast milk-derived extracellular vesicle microRNAs in the programming of intergenerational stress mechanisms (PRI	20
Identification of 20 novel loci associated with ischaemic stroke. Epigenome-wide association study	20

The m6A epitranscriptome opens a new charter in immune system logic	19
The DNA methylation landscape of human cancer organoids available at the American type culture collection	19
Sex-specific associations with DNA methylation in lung tissue demonstrate smoking interactions	19
Reliability of DNA methylation measures using Illumina methylation BeadChip	19
Test-statistic inflation in methylome-wide association studies	19
Clinical epigenetics and multidrug-resistant bacterial infections: host remodelling in critical illness	18
Epigenetic alterations as therapeutic targets in Testicular Germ Cell Tumours : current and future application of ‘epidrugs’	18
Sources of variation of DNA methylation in rainbow trout: combined effects of temperature and genetic background	18
Comparison of EM-seq and PBAT methylome library methods for low-input DNA	18
Hypermethylation and global remodelling of DNA methylation is associated with acquired cisplatin resistance in testicular germ cell tumours	18
Dietary inclusion of plant ingredients induces epigenetic changes in the intestine of zebrafish	17
Chromatin profiling reveals relocalization of lysine-specific demethylase 1 by an oncogenic fusion protein	17
Genome-wide study of the effect of blood collection tubes on the cell-free DNA methylome	17
Enrichment of CpG island shore region hypermethylation in epigenetic breast field cancerization	16
HIV-1 Tat and cocaine impact mitochondrial epigenetics: effects on DNA methylation	16
DNA methylation in the promoters of PD-L1, MMP9, ARG1, galectin-9, TIM-3, VISTA and TGF-β genes in HLA-DR^– myeloid cells, compared with HLA-DR⁺ antigen-presenting cells	16
Neuronal Lhx1 expression is regulated by DNMT1-dependent modulation of histone marks	16
Hypermethylation of the oxytocin receptor gene (OXTR) in obsessive-compulsive disorder: further evidence for a biomarker of disease and treatment response	16
DNA demethylation is a driver for chick retina regeneration	16
Adolescent sleep timing and dietary patterns in relation to DNA methylation of core circadian genes: a pilot study of Mexican youth	16
Maternal prenatal depression and epigenetic age deceleration: testing potentially confounding effects of prenatal stress and SSRI use	16
Longitudinal data reveal strong genetic and weak non-genetic components of ethnicity-dependent blood DNA methylation levels	16
Birth weight associations with DNA methylation differences in an adult population	15
Characterizing the dynamic and functional DNA methylation landscape in the developing human cortex	15
DNA methylation profiling identifies a high effect genetic variant for lipoprotein(a) levels	14
Tissue and sex-specific programming of DNA methylation by perinatal lead exposure: implications for environmental epigenetics studies	14
Global epigenetic alterations of mesenchymal stem cells in obesity: the role of vitamin C reprogramming	14
TET family regulates the embryonic pluripotency of porcine preimplantation embryos by maintaining the DNA methylation level of NANOG	14
m⁶A RNA demethylase FTO promotes the growth, migration and invasion of pancreatic cancer cells through inhibiting TFPI-2	14
Salinomycin inhibits epigenetic modulator EZH2 to enhance death receptors in colon cancer stem cells	14
Epigenome-wide cross-tissue correlation of human bone and blood DNA methylation – can blood be used as a surrogate for bone?	14
Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome	14
Global DNA (hydroxy)methylation is stable over time under several storage conditions and temperatures	13
The epigenetics of breast cancer – Opportunities for diagnostics, risk stratification and therapy	13
DNA methylation as a mediator of associations between the environment and chronic diseases: A scoping review on application of mediation analysis	13
microRNA27a-3p mediates reduction of the Wnt antagonist sFRP-1 in systemic sclerosis	13
Methylomic Signatures of High Grade Serous Ovarian Cancer	13
DNA methylation signatures of adolescent victimization: analysis of a longitudinal monozygotic twin sample	13
The epitranscriptomic writer ALKBH8 drives tolerance and protects mouse lungs from the environmental pollutant naphthalene	13
Cell-free DNA methylome profiling by MBD-seq with ultra-low input	13
The DNA methylome of inflammatory bowel disease (IBD) reflects intrinsic and extrinsic factors in intestinal mucosal cells	13
Comprehensive analysis of transcriptome-wide m⁶A methylome in the anterior capsule of the lens of high myopia patients	13
Associations between infant sex and DNA methylation across umbilical cord blood, artery, and placenta samples	12
Genome-wide DNA methylation differences and polychlorinated biphenyl (PCB) exposure in a US population	12
Maternal blood metal concentrations and whole blood DNA methylation during pregnancy in the Early Autism Risk Longitudinal Investigation (EARLI)	12
Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications	12
Genome-wide microRNA expression analysis in human placenta reveals sex-specific patterns: an ENVIRONAGE birth cohort study	12
Suppressing circIDE/miR-19b-3p/RBMS1 axis exhibits promoting-tumour activity through upregulating GPX4 to diminish ferroptosis in hepatocellular carcinoma	12
Extracellular vesicle microRNA in early versus late pregnancy with birth outcomes in the MADRES study	12
Effects of substrate modifications on the arginine dimethylation activities of PRMT1 and PRMT5	12

Cell type-specific chromatin accessibility analysis in the mouse and human brain	12
Methylation of FKBP5 is associated with accelerated DNA methylation ageing and cardiometabolic risk: replication in young-adult and middle-aged Black Americans	11
A mathematical model exhibiting the effect of DNA methylation on the stability boundary in cell-fate networks	11
Epigenome-wide analysis of long-term air pollution exposure and DNA methylation in monocytes: results from the Multi-Ethnic Study of Atherosclerosis	11
Hypermethylation of PI3K-AKT signalling pathway genes is associated with human neural tube defects	11
Association ofSOD3 promoter DNA methylation with its down-regulation in breast carcinomas	11
Molecular signatures identified by integrating gene expression and methylation in non-seminoma and seminoma of testicular germ cell tumours	11
A comparison of epithelial cell content of oral samples estimated using cytology and DNA methylation	11
Early epigenetic changes of Alzheimer’s disease in the human hippocampus	11
DNA methylation differentiates smoking from vaping and non-combustible tobacco use	11
DNA methylation ageing clocks and pancreatic cancer risk: pooled analysis of three prospective nested case-control studies	11
Overlapping functions of RBBP4 and RBBP7 in regulating cell proliferation and histone H3.3 deposition during mouse preimplantation development	11
DNA methylation and hydroxymethylation have distinct genome-wide profiles related to axonal regeneration	11
Exposure to extracellular vesicles from Pseudomonas aeruginosa result in loss of DNA methylation at enhancer and DNase hypersensitive site regions in lung macrophages	11
NAT10 mediated mRNA acetylation modification patterns associated with colon cancer progression and microsatellite status	10
Placental microRNA expression associates with birthweight through control of adipokines: results from two independent cohorts	10
Urinary metals and maternal circulating extracellular vesicle microRNA in the MADRES pregnancy cohort	10
m ⁶ A-modification regulated circ-CCT3 acts as the sponge of miR-378a-3p to promote hepatocellular carcinoma progression	10
A genome-wide study of DNA methylation in white blood cells and asthma in Latino children and youth	10
Epigenome-wide scan identifies differentially methylated regions for lung cancer using pre-diagnostic peripheral blood	10
Replicated umbilical cord blood DNA methylation loci associated with gestational age at birth	10
Identifying cortical specific long noncoding RNAs modified by m⁶A RNA methylation in mouse brains	10
Dynamic changes in DNA methylation occur in TE regions and affect cell proliferation during leaf-to-callus transition in Arabidopsis	10
A novel CpG-methylation-based nomogram predicts survival in colorectal cancer	10
Early fish domestication affects methylation of key genes involved in the rapid onset of the farmed phenotype	10
Maternal atopy and offspring epigenome-wide methylation signature	10
DNA methylation changes in glial cells of the normal-appearing white matter in Multiple Sclerosis patients	10
Upregulation of polycistronic microRNA-143 and microRNA-145 in colonocytes suppresses colitis and inflammation-associated colon cancer	9
DNA methylation biomarker selected by an ensemble machine learning approach predicts mortality risk in an HIV-positive veteran population	9
Epigenetic regulation of miR-518a-5p-CCR6 feedback loop promotes both proliferation and invasion in diffuse large B cell lymphoma	9
Germline DNMT3A mutation in familial acute myeloid leukaemia	9
“Epigenome-wide methylation profile of chronic kidney disease-derived arterial DNA uncovers novel pathways in disease-associated cardiovascular pathology.”	9
Adiposity associated DNA methylation signatures in adolescents are related to leptin and perinatal factors	9
Prenatal smoke exposure induces persistent Cyp2a5 methylation and increases nicotine metabolism in the liver of neonatal and adult male offspring	9
DNA methylome in visceral adipose tissue can discriminate patients with and without colorectal cancer	9
Epigenome-wide association study identifies DNA methylation sites associated with target organ damage in older African Americans	9
Validation of a DNA methylation microarray for 285,000 CpG sites in the mouse genome	9
Perinatal stress and methylation of the NR3C1 gene in newborns: systematic review	9
Dynamic chromatin accessibility landscape changes following interleukin-1 stimulation	9
Epigenetic Aging Mediates the Association between Pain Impact and Brain Aging in Middle to Older Age Individuals with Knee Pain	9
Tumour suppressor TET2 safeguards enhancers from aberrant DNA methylation and epigenetic reprogramming in ERα-positive breast cancer cells	9