OOIR: Observatory of International Research

Papers

(The TQCC of Epigenetics is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Genome-wide CpG density and DNA methylation analysis method (MeDIP, RRBS, and WGBS) comparisons	66
The Socioeconomic Gradient in Epigenetic Ageing Clocks: Evidence from the Multi-Ethnic Study of Atherosclerosis and the Health and Retirement Study	55
Saliva cell type DNA methylation reference panel for epidemiological studies in children	37
Epigenome-wide association study for glyphosate induced transgenerational sperm DNA methylation and histone retention epigenetic biomarkers for disease	32
Genomic map of candidate human imprint control regions: the imprintome	31
Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome	31
DNA methylation profile of genes involved in inflammation and autoimmunity correlates with vascular function in morbidly obese adults	27
Micronutrient supplementation affects transcriptional and epigenetic regulation of lipid metabolism in a dose-dependent manner	26
Comparison of EM-seq and PBAT methylome library methods for low-input DNA	24
Hypermethylation of the oxytocin receptor gene (OXTR) in obsessive-compulsive disorder: further evidence for a biomarker of disease and treatment response	19
DNA methylation differentiates smoking from vaping and non-combustible tobacco use	18
Suppressing circIDE/miR-19b-3p/RBMS1 axis exhibits promoting-tumour activity through upregulating GPX4 to diminish ferroptosis in hepatocellular carcinoma	18
m⁶A RNA demethylase FTO promotes the growth, migration and invasion of pancreatic cancer cells through inhibiting TFPI-2	18
DNA methylation signatures of adolescent victimization: analysis of a longitudinal monozygotic twin sample	17
Methylomic Signatures of High Grade Serous Ovarian Cancer	16
Tissue and sex-specific programming of DNA methylation by perinatal lead exposure: implications for environmental epigenetics studies	16
Cell-free DNA methylome profiling by MBD-seq with ultra-low input	16
Associations between infant sex and DNA methylation across umbilical cord blood, artery, and placenta samples	16
The epigenetics of breast cancer – Opportunities for diagnostics, risk stratification and therapy	16
Early fish domestication affects methylation of key genes involved in the rapid onset of the farmed phenotype	16
Extracellular vesicle microRNA in early versus late pregnancy with birth outcomes in the MADRES study	15
Maternal blood metal concentrations and whole blood DNA methylation during pregnancy in the Early Autism Risk Longitudinal Investigation (EARLI)	15
Epigenome-wide analysis of long-term air pollution exposure and DNA methylation in monocytes: results from the Multi-Ethnic Study of Atherosclerosis	15
A comparison of epithelial cell content of oral samples estimated using cytology and DNA methylation	15
DNA methylation changes in glial cells of the normal-appearing white matter in Multiple Sclerosis patients	14

Epigenome-wide scan identifies differentially methylated regions for lung cancer using pre-diagnostic peripheral blood	14
Exposure to extracellular vesicles from Pseudomonas aeruginosa result in loss of DNA methylation at enhancer and DNase hypersensitive site regions in lung macrophages	14
Overlapping functions of RBBP4 and RBBP7 in regulating cell proliferation and histone H3.3 deposition during mouse preimplantation development	14
NAT10 mediated mRNA acetylation modification patterns associated with colon cancer progression and microsatellite status	13
Hypermethylation of PI3K-AKT signalling pathway genes is associated with human neural tube defects	13
Cell type-specific chromatin accessibility analysis in the mouse and human brain	13
m ⁶ A-modification regulated circ-CCT3 acts as the sponge of miR-378a-3p to promote hepatocellular carcinoma progression	13
Identification and comparison of m6A modifications in glioblastoma non-coding RNAs with MeRIP-seq and Nanopore dRNA-seq	13
Validation of a DNA methylation microarray for 285,000 CpG sites in the mouse genome	13
DNA methylation as a mediator of associations between the environment and chronic diseases: A scoping review on application of mediation analysis	13
LncRNA TUG1 promotes pulmonary fibrosis progression via up-regulating CDC27 and activating PI3K/Akt/mTOR pathway	12
Methylation of FKBP5 is associated with accelerated DNA methylation ageing and cardiometabolic risk: replication in young-adult and middle-aged Black Americans	12
Effects of substrate modifications on the arginine dimethylation activities of PRMT1 and PRMT5	12
Adiposity associated DNA methylation signatures in adolescents are related to leptin and perinatal factors	11
DNA methylome in visceral adipose tissue can discriminate patients with and without colorectal cancer	11
Dynamic changes in DNA methylation occur in TE regions and affect cell proliferation during leaf-to-callus transition in Arabidopsis	11
Urinary metals and maternal circulating extracellular vesicle microRNA in the MADRES pregnancy cohort	11
Maternal Mediterranean diet in pregnancy and newborn DNA methylation: a meta-analysis in the PACE Consortium	11
Identifying cortical specific long noncoding RNAs modified by m⁶A RNA methylation in mouse brains	11
RNA modification m ⁶ Am: the role in cardiac biology	10
Perinatal stress and methylation of the NR3C1 gene in newborns: systematic review	10
Weight loss reduces circulating micro-RNA related to obesity and breast cancer in postmenopausal women	10
The effect of experimental lead pollution on DNA methylation in a wild bird population	10
Repurposing epigenetic inhibitors to target the Clostridioides difficile-specific DNA adenine methyltransferase and sporulation regulator CamA	10
NSUN2-mediated RNA m⁵C modification modulates uveal melanoma cell proliferation and migration	10
Upregulation of polycistronic microRNA-143 and microRNA-145 in colonocytes suppresses colitis and inflammation-associated colon cancer	10
Functional study and epigenetic targets analyses of SIRT1 in intramuscular preadipocytes via ChIP-seq and mRNA-seq	10
Birth weight and maternal energy status during pregnancy as predictors of epigenetic age acceleration in young adults from metropolitan Cebu, Philippines	10
Human non-CpG methylation patterns display both tissue-specific and inter-individual differences suggestive of underlying function	10
Occupational characteristics and epigenetic aging among older adults in the United States	9
Prenatal medication exposure and epigenetic outcomes: a systematic literature review and recommendations for prenatal pharmacoepigenetic studies	9
A methodological pipeline to generate an epigenetic marker of prenatal exposure to air pollution indicators	9
Epigenetic Aging Mediates the Association between Pain Impact and Brain Aging in Middle to Older Age Individuals with Knee Pain	9
Oleic acid-related anti-inflammatory effects in force-stressed PdL fibroblasts are mediated by H3 lysine acetylation associated with altered IL10 expression	9
Tumour suppressor TET2 safeguards enhancers from aberrant DNA methylation and epigenetic reprogramming in ERα-positive breast cancer cells	9
Prenatal and birth associations of epigenetic gestational age acceleration in the Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS) cohort	9
Sex-based differences in placental DNA methylation profiles related to gestational age: an NIH ECHO meta-analysis	9
Prenatal maternal stress is associated with site-specific and age acceleration changes in maternal and newborn DNA methylation	9
Histone deacetylase 3 regulates microglial function through histone deacetylation	9
A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation	9
DNA methylation ageing clocks and pancreatic cancer risk: pooled analysis of three prospective nested case-control studies	9
Up-regulation of LINC00619 promotes apoptosis and inhibits proliferation, migration and invasion while promoting apoptosis of osteosarcoma cells through inactivation of the HGF-mediated PI3K-Akt signa	8
Biological stability of DNA methylation measurements over varying intervals of time and in the presence of acute stress	8
DNA-methylation for the detection and distinction of 19 human malignancies	8
Spatiotemporal specificity of correlated DNA methylation and gene expression pairs across different human tissues and stages of brain development	8
CircDHRS3 inhibits prostate cancer cell proliferation and metastasis through the circDHRS3/miR-421/MEIS2 axis	8
Identification and characterization of extrachromosomal circular DNA in patients with high myopia and cataract	8
CircRNF111 Contributes to Adipocyte Differentiation by Elevating PPARγ Expression via miR-27a-3p	8
Epigenome-wide association studies of occupational exposure to benzene and formaldehyde	8
Placental DNA methylation in pregnancies complicated by maternal diabetes and/or obesity: State of the art and research gaps	8

Reproducibility of the Infinium methylationEPIC BeadChip assay using low DNA amounts	8
Long non-coding RNA Gm10561 promotes myogenesis by sponging miR-432	8
Potential functions of histone H3.3 lysine 56 acetylation in mammals	8
Placental epigenetic gestational aging in relation to maternal sociodemographic factors and smoking among infants born extremely preterm: a descriptive study	8
Feminization of channel catfish with 17β-oestradiol involves methylation and expression of a specific set of genes independent of the sex determination region	8
Uncertainty quantification of reference-based cellular deconvolution algorithms	8
Epigenetic control of the imprinted growth regulator Cdkn1c in cadmium-induced placental dysfunction	8
DNA methylation profiles in pneumonia patients reflect changes in cell types and pneumonia severity	8
Epigenetic mechanisms underlying the association between maternal climate stress and child growth: characterizing severe drought and its impact on a Kenyan community engaging in a climate change-sensi	8
Association between dietary patterns reflecting one-carbon metabolism nutrients intake before pregnancy and placental DNA methylation	8
Circulating miRNAs in the first trimester and pregnancy complications: a systematic review	8
Radiation-induced cardiovascular disease: an overlooked role for DNA methylation?	8
ABCA1, TCF7, NFATC1, PRKCZ, and PDGFA DNA methylation as potential epigenetic-sensitive targets in acute coronary syndrome via network analysis	8
Pharmacoepigenetics of hypertension: genome-wide methylation analysis of responsiveness to four classes of antihypertensive drugs using a double-blind crossover study design	8
Targeted disruption of the histone lysine 79 methyltransferase Dot1L in nephron progenitors causes congenital renal dysplasia	7
Novel DNA methylation loci and genes showing pleiotropic association with Alzheimer’s dementia: a network Mendelian randomization analysis	7
Impact of tobacco, alcohol, and marijuana on genome-wide DNA methylation and its relationship with hypertension	7
Loss of KMT2C reprograms the epigenomic landscape in hPSCs resulting in NODAL overexpression and a failure of hemogenic endothelium specification	7
Epigenome-wide association study and network analysis for IgA Nephropathy from CD19⁺B-cell in Chinese Population	7
CD4⁺T-cell DNA methylation changes during pregnancy significantly correlate with disease-associated methylation changes in autoimmune diseases	7
Roles of adenine methylation and genetic mutations in adaptation to different temperatures in Serratia marcescens	7
Fusaric acid induces hepatic global m6A RNA methylation and differential expression of m6A regulatory genes in vivo - a pilot study	7
Circ_0078607 increases platinum drug sensitivity via miR-196b-5p/GAS7 axis in ovarian cancer	7
Exploring the impact of night shift work on methylation of circadian genes	7
Cumulative stress, PTSD, and emotion dysregulation during pregnancy and epigenetic age acceleration in Hispanic mothers and their newborn infants	7
Key changes in chromatin mark mammalian epidermal differentiation and ageing	7
Updates to data versions and analytic methods influence the reproducibility of results from epigenome-wide association studies	7
Digital methylation assessments of alcohol and cigarette consumption account for common variance in accelerated epigenetic ageing	7
A comprehensive atlas of epigenetic regulators reveals tissue-specific epigenetic regulation patterns	7
Differentially methylated regions (DMRs) in PON3 gene between responders and non-responders to a weight loss dietary intervention: a new tool for precision management of obesity	7
Genome-wide DNA methylation of the liver reveals delayed effects of early-life exposure to 17-α-ethinylestradiol in the self-fertilizing mangrove rivulus	7