Epigenetics

Article	Citations
Epigenetic mechanisms regulating COVID-19 infection	96
Comprehensive analysis of the transcriptome-wide m6A methylome in colorectal cancer by MeRIP sequencing	47
Genome-wide CpG density and DNA methylation analysis method (MeDIP, RRBS, and WGBS) comparisons	46
The Socioeconomic Gradient in Epigenetic Ageing Clocks: Evidence from the Multi-Ethnic Study of Atherosclerosis and the Health and Retirement Study	36
Saliva cell type DNA methylation reference panel for epidemiological studies in children	34
Cell-free DNA Methylation and Transcriptomic Signature Prediction of Pregnancies with Adverse Outcomes	32
The landscape of accessible chromatin in bovine oocytes and early embryos	32
Major gene expression changes and epigenetic remodelling in Nile tilapia muscle after just one generation of domestication	31
Estrogen-induced epigenetic silencing of FTH1 and TFRC genes reduces liver cancer cell growth and survival	31
Fusaric acid decreases p53 expression by altering promoter methylation and m6A RNA methylation in human hepatocellular carcinoma (HepG2) cells	28
SET1/MLL family of proteins: functions beyond histone methylation	27
The landscape of CD28, CD80, CD86, CTLA4, and ICOS DNA methylation in head and neck squamous cell carcinomas	27
Mitochondrial DNA methylation in placental tissue: a proof of concept study by means of prenatal environmental stressors	26
Epigenome-wide association study for glyphosate induced transgenerational sperm DNA methylation and histone retention epigenetic biomarkers for disease	26
The myonuclear DNA methylome in response to an acute hypertrophic stimulus	26
Prenatal gestational diabetes mellitus exposure and accelerated offspring DNA methylation age in early childhood	25
Genomic map of candidate human imprint control regions: the imprintome	23
DNA methylation profile of genes involved in inflammation and autoimmunity correlates with vascular function in morbidly obese adults	23
Music-listening regulates human microRNA expression	23
DNA methylation in promoter regions of genes involved in the reproductive and metabolic function of children born to women with PCOS	21
Recent insights intoHistone Acetyltransferase-1: biological function and involvement in pathogenesis	21
Micronutrient supplementation affects transcriptional and epigenetic regulation of lipid metabolism in a dose-dependent manner	21
Betaine restores epigenetic control and supports neuronal mitochondria in the cuprizone mouse model of multiple sclerosis	21
Minimally invasive classification of paediatric solid tumours using reduced representation bisulphite sequencing of cell-free DNA: a proof-of-principle study	20
Associations between maternal lifetime stressors and negative events in pregnancy and breast milk-derived extracellular vesicle microRNAs in the programming of intergenerational stress mechanisms (PRI	20

Test-statistic inflation in methylome-wide association studies	19
Identification of 20 novel loci associated with ischaemic stroke. Epigenome-wide association study	19
Sex-specific associations with DNA methylation in lung tissue demonstrate smoking interactions	18
Comparison of EM-seq and PBAT methylome library methods for low-input DNA	18
Reliability of DNA methylation measures using Illumina methylation BeadChip	18
Sources of variation of DNA methylation in rainbow trout: combined effects of temperature and genetic background	18
Hypermethylation and global remodelling of DNA methylation is associated with acquired cisplatin resistance in testicular germ cell tumours	18
Clinical epigenetics and multidrug-resistant bacterial infections: host remodelling in critical illness	18
The DNA methylation landscape of human cancer organoids available at the American type culture collection	18
Epigenetic alterations as therapeutic targets in Testicular Germ Cell Tumours : current and future application of ‘epidrugs’	18
The m6A epitranscriptome opens a new charter in immune system logic	17
Chromatin profiling reveals relocalization of lysine-specific demethylase 1 by an oncogenic fusion protein	17
Genome-wide study of the effect of blood collection tubes on the cell-free DNA methylome	17
The emerging role of epigenetics in the immune response to vaccination and infection: a systematic review	16
Dietary inclusion of plant ingredients induces epigenetic changes in the intestine of zebrafish	16
DNA demethylation is a driver for chick retina regeneration	16
Enrichment of CpG island shore region hypermethylation in epigenetic breast field cancerization	16
HIV-1 Tat and cocaine impact mitochondrial epigenetics: effects on DNA methylation	16
Neuronal Lhx1 expression is regulated by DNMT1-dependent modulation of histone marks	16
DNA methylation in the promoters of PD-L1, MMP9, ARG1, galectin-9, TIM-3, VISTA and TGF-β genes in HLA-DR– myeloid cells, compared with HLA-DR+ antigen-presenting cells	16
Promoter hypermethylation of PIWI/piRNA pathway genes associated with diminished pachytene piRNA production in bovine hybrid male sterility	15
Hypermethylation of the oxytocin receptor gene (OXTR) in obsessive-compulsive disorder: further evidence for a biomarker of disease and treatment response	15
Adolescent sleep timing and dietary patterns in relation to DNA methylation of core circadian genes: a pilot study of Mexican youth	15
Characterizing the dynamic and functional DNA methylation landscape in the developing human cortex	15
Effects of Maternal Vitamin D3 Supplementation on Offspring Epigenetic Clock of Gestational Age at Birth: A Post-hoc Analysis of a Randomized Controlled Trial	15
Chromatin structure regulates cancer-specific alternative splicing events in primary HPV-related oropharyngeal squamous cell carcinoma	15
Maternal prenatal depression and epigenetic age deceleration: testing potentially confounding effects of prenatal stress and SSRI use	15
Longitudinal data reveal strong genetic and weak non-genetic components of ethnicity-dependent blood DNA methylation levels	15
Birth weight associations with DNA methylation differences in an adult population	14
Epigenome-wide cross-tissue correlation of human bone and blood DNA methylation – can blood be used as a surrogate for bone?	14
Global epigenetic alterations of mesenchymal stem cells in obesity: the role of vitamin C reprogramming	14
TET family regulates the embryonic pluripotency of porcine preimplantation embryos by maintaining the DNA methylation level of NANOG	14
Salinomycin inhibits epigenetic modulator EZH2 to enhance death receptors in colon cancer stem cells	14
Tissue and sex-specific programming of DNA methylation by perinatal lead exposure: implications for environmental epigenetics studies	14
m6A RNA demethylase FTO promotes the growth, migration and invasion of pancreatic cancer cells through inhibiting TFPI-2	14
The epigenetics of breast cancer – Opportunities for diagnostics, risk stratification and therapy	13
DNA methylation profiling identifies a high effect genetic variant for lipoprotein(a) levels	13
DNA methylation as a mediator of associations between the environment and chronic diseases: A scoping review on application of mediation analysis	13
Comprehensive analysis of transcriptome-wide m6A methylome in the anterior capsule of the lens of high myopia patients	13
The DNA methylome of inflammatory bowel disease (IBD) reflects intrinsic and extrinsic factors in intestinal mucosal cells	13
Methylomic Signatures of High Grade Serous Ovarian Cancer	12
Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications	12
The epitranscriptomic writer ALKBH8 drives tolerance and protects mouse lungs from the environmental pollutant naphthalene	12
Global DNA (hydroxy)methylation is stable over time under several storage conditions and temperatures	12
Maternal blood metal concentrations and whole blood DNA methylation during pregnancy in the Early Autism Risk Longitudinal Investigation (EARLI)	12
Cell type-specific chromatin accessibility analysis in the mouse and human brain	12
Associations between infant sex and DNA methylation across umbilical cord blood, artery, and placenta samples	12
Suppressing circIDE/miR-19b-3p/RBMS1 axis exhibits promoting-tumour activity through upregulating GPX4 to diminish ferroptosis in hepatocellular carcinoma	12
microRNA27a-3p mediates reduction of the Wnt antagonist sFRP-1 in systemic sclerosis	12
DNA methylation signatures of adolescent victimization: analysis of a longitudinal monozygotic twin sample	11

DNA methylation differentiates smoking from vaping and non-combustible tobacco use	11
Extracellular vesicle microRNA in early versus late pregnancy with birth outcomes in the MADRES study	11
Genome-wide microRNA expression analysis in human placenta reveals sex-specific patterns: an ENVIRONAGE birth cohort study	11
DNA methylation and hydroxymethylation have distinct genome-wide profiles related to axonal regeneration	11
Exposure to extracellular vesicles from Pseudomonas aeruginosa result in loss of DNA methylation at enhancer and DNase hypersensitive site regions in lung macrophages	11
Association ofSOD3 promoter DNA methylation with its down-regulation in breast carcinomas	11
Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome	11
Molecular signatures identified by integrating gene expression and methylation in non-seminoma and seminoma of testicular germ cell tumours	11
Effects of substrate modifications on the arginine dimethylation activities of PRMT1 and PRMT5	11
Cell-free DNA methylome profiling by MBD-seq with ultra-low input	11
Early epigenetic changes of Alzheimer’s disease in the human hippocampus	11
Methylation of FKBP5 is associated with accelerated DNA methylation ageing and cardiometabolic risk: replication in young-adult and middle-aged Black Americans	11
A mathematical model exhibiting the effect of DNA methylation on the stability boundary in cell-fate networks	11
Epigenome-wide association study reveals a molecular signature of response to phylloquinone (vitamin K1) supplementation	11
Epigenome-wide analysis of long-term air pollution exposure and DNA methylation in monocytes: results from the Multi-Ethnic Study of Atherosclerosis	11
A genome-wide study of DNA methylation in white blood cells and asthma in Latino children and youth	10
Hypermethylation of PI3K-AKT signalling pathway genes is associated with human neural tube defects	10
DNA methylation ageing clocks and pancreatic cancer risk: pooled analysis of three prospective nested case-control studies	10
A comparison of epithelial cell content of oral samples estimated using cytology and DNA methylation	10
Urinary metals and maternal circulating extracellular vesicle microRNA in the MADRES pregnancy cohort	10
NAT10 mediated mRNA acetylation modification patterns associated with colon cancer progression and microsatellite status	10
Early fish domestication affects methylation of key genes involved in the rapid onset of the farmed phenotype	10
Genome-wide DNA methylation differences and polychlorinated biphenyl (PCB) exposure in a US population	10
Maternal atopy and offspring epigenome-wide methylation signature	10
Overlapping functions of RBBP4 and RBBP7 in regulating cell proliferation and histone H3.3 deposition during mouse preimplantation development	10
A novel CpG-methylation-based nomogram predicts survival in colorectal cancer	10
Epigenome-wide scan identifies differentially methylated regions for lung cancer using pre-diagnostic peripheral blood	10
Placental microRNA expression associates with birthweight through control of adipokines: results from two independent cohorts	10
Replicated umbilical cord blood DNA methylation loci associated with gestational age at birth	10
Aberrant hydroxymethylation of ANGPTL4 is associated with selective intrauterine growth restriction in monochorionic twin pregnancies	10
Identifying cortical specific long noncoding RNAs modified by m6A RNA methylation in mouse brains	10
Upregulation of polycistronic microRNA-143 and microRNA-145 in colonocytes suppresses colitis and inflammation-associated colon cancer	9
Prenatal smoke exposure induces persistent Cyp2a5 methylation and increases nicotine metabolism in the liver of neonatal and adult male offspring	9
Epigenetic Aging Mediates the Association between Pain Impact and Brain Aging in Middle to Older Age Individuals with Knee Pain	9
Epigenome-wide association study identifies DNA methylation sites associated with target organ damage in older African Americans	9
DNA methylation changes in glial cells of the normal-appearing white matter in Multiple Sclerosis patients	9
Adiposity associated DNA methylation signatures in adolescents are related to leptin and perinatal factors	9
Perinatal stress and methylation of the NR3C1 gene in newborns: systematic review	9
Germline DNMT3A mutation in familial acute myeloid leukaemia	9
Tumour suppressor TET2 safeguards enhancers from aberrant DNA methylation and epigenetic reprogramming in ERα-positive breast cancer cells	9
Validation of a DNA methylation microarray for 285,000 CpG sites in the mouse genome	9
“Epigenome-wide methylation profile of chronic kidney disease-derived arterial DNA uncovers novel pathways in disease-associated cardiovascular pathology.”	9
Epigenetic regulation of miR-518a-5p-CCR6 feedback loop promotes both proliferation and invasion in diffuse large B cell lymphoma	9
Comparative analysis of genome-wide DNA methylation in Neurospora	9
Dynamic changes in DNA methylation occur in TE regions and affect cell proliferation during leaf-to-callus transition in Arabidopsis	9
The hypomethylation of imprinted genes in IVF/ICSI placenta samples is associated with concomitant changes in histone modifications	8
A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation	8
A methodological pipeline to generate an epigenetic marker of prenatal exposure to air pollution indicators	8
DNA methylome in visceral adipose tissue can discriminate patients with and without colorectal cancer	8
ABCA1, TCF7, NFATC1, PRKCZ, and PDGFA DNA methylation as potential epigenetic-sensitive targets in acute coronary syndrome via network analysis	8
Ten-eleven translocation proteins and their role beyond DNA demethylation – what we can learn from the fly	8
The effect of experimental lead pollution on DNA methylation in a wild bird population	8
Maternal Mediterranean diet in pregnancy and newborn DNA methylation: a meta-analysis in the PACE Consortium	8
Dynamic chromatin accessibility landscape changes following interleukin-1 stimulation	8
Repurposing epigenetic inhibitors to target the Clostridioides difficile-specific DNA adenine methyltransferase and sporulation regulator CamA	8
A Comparison of the Predictive Power of DNA Methylation with Carbohydrate Deficient Transferrin for Heavy Alcohol Consumption	8
Prenatal medication exposure and epigenetic outcomes: a systematic literature review and recommendations for prenatal pharmacoepigenetic studies	8
m 6 A-modification regulated circ-CCT3 acts as the sponge of miR-378a-3p to promote hepatocellular carcinoma progression	8
Long non-coding RNA Gm10561 promotes myogenesis by sponging miR-432	8
DNA methylation biomarker selected by an ensemble machine learning approach predicts mortality risk in an HIV-positive veteran population	8
Age-related DNA methylation in paired normal and tumour breast tissue in Chinese breast cancer patients	8
Methylation of cysteinyl leukotriene receptor 1 genes associates with lung function in asthmatics exposed to traffic-related air pollution	8
Deacetylation of H4 lysine16 affects acetylation of lysine residues in histone H3 and H4 and promotes transcription of constitutive genes	8
Dynamic shifts in chromatin states differentially mark the proliferative basal cells and terminally differentiated cells of the developing epidermis	7
Updates to data versions and analytic methods influence the reproducibility of results from epigenome-wide association studies	7
Establishment of diagnostic criteria for upper urinary tract urothelial carcinoma based on genome-wide DNA methylation analysis	7
The curious case of Merkel cell carcinoma: epigenetic youth and lack of pluripotency	7
Reproducibility of the Infinium methylationEPIC BeadChip assay using low DNA amounts	7
Functional study and epigenetic targets analyses of SIRT1 in intramuscular preadipocytes via ChIP-seq and mRNA-seq	7
DNA-methylation for the detection and distinction of 19 human malignancies	7
CYP2S1 might regulate proliferation and immune response of keratinocyte in psoriasis	7
Novel DNA methylation loci and genes showing pleiotropic association with Alzheimer’s dementia: a network Mendelian randomization analysis	7
Genome-wide DNA methylation profiling in human breast tissue by Illumina TruSeq methyl capture EPIC sequencing and infinium methylationEPIC beadchip microarray	7
Human non-CpG methylation patterns display both tissue-specific and inter-individual differences suggestive of underlying function	7
Up-regulation of LINC00619 promotes apoptosis and inhibits proliferation, migration and invasion while promoting apoptosis of osteosarcoma cells through inactivation of the HGF-mediated PI3K-Akt signa	7
The landscape of accessible chromatin in quiescent cardiac fibroblasts and cardiac fibroblasts activated after myocardial infarction	7
Identification of the origin of brain metastases based on the relative methylation orderings of CpG sites	7
DNA methylation patterns respond to thermal stress in the viviparous cockroachDiploptera punctata	7
Radiation-induced cardiovascular disease: an overlooked role for DNA methylation?	7
Oleic acid-related anti-inflammatory effects in force-stressed PdL fibroblasts are mediated by H3 lysine acetylation associated with altered IL10 expression	7

Birth weight and maternal energy status during pregnancy as predictors of epigenetic age acceleration in young adults from metropolitan Cebu, Philippines	7
Prenatal and birth associations of epigenetic gestational age acceleration in the Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS) cohort	7
Loss of KMT2C reprograms the epigenomic landscape in hPSCs resulting in NODAL overexpression and a failure of hemogenic endothelium specification	7
Association between dietary patterns reflecting one-carbon metabolism nutrients intake before pregnancy and placental DNA methylation	7
Potential functions of histone H3.3 lysine 56 acetylation in mammals	6
Targeted disruption of the histone lysine 79 methyltransferase Dot1L in nephron progenitors causes congenital renal dysplasia	6
Cytosine methylation patterns suggest a role of methylation in plastic and adaptive responses to temperature in European grayling (Thymallus thymallus) populations	6
Epigenetic control of the imprinted growth regulator Cdkn1c in cadmium-induced placental dysfunction	6
Extracellular microRNA 3’ end modification across diverse body fluids	6
Genome-wide DNA methylation of the liver reveals delayed effects of early-life exposure to 17-α-ethinylestradiol in the self-fertilizing mangrove rivulus	6
Application of Recombination -Induced Tag Exchange (RITE) to study histone dynamics in human cells	6
Fusaric acid induces hepatic global m6A RNA methylation and differential expression of m6A regulatory genes in vivo - a pilot study	6
Epigenome-wide association study and network analysis for IgA Nephropathy from CD19+B-cell in Chinese Population	6
Prenatal exposure to endocrine disrupting chemicals is associated with altered DNA methylation in cord blood	6
Network modules linking expression and methylation in prefrontal cortex of schizophrenia	6
Pharmacoepigenetics of hypertension: genome-wide methylation analysis of responsiveness to four classes of antihypertensive drugs using a double-blind crossover study design	6
Identification and comparison of m6A modifications in glioblastoma non-coding RNAs with MeRIP-seq and Nanopore dRNA-seq	5
Sex-based differences in placental DNA methylation profiles related to gestational age: an NIH ECHO meta-analysis	5
Histone variants in skeletal myogenesis	5
NSUN2-mediated RNA m5C modification modulates uveal melanoma cell proliferation and migration	5
Epigenetic ageing of the prefrontal cortex and cerebellum in humans and chimpanzees	5
Using Cg05575921 methylation to predict lung cancer risk: a potentially bias-free precision epigenetics approach	5
A key regulatory loop AK4P1/miR-375/SP1 in pancreatic adenocarcinoma	5
Assessment of aberrant DNA methylation two years after paediatric critical illness: a pre-planned secondary analysis of the international PEPaNIC trial	5
DNA methylation profiles in pneumonia patients reflect changes in cell types and pneumonia severity	5
RNA modification m 6 Am: the role in cardiac biology	5
Direct bisulphite conversion of cervical samples for DNA methylation analysis	5
Epigenetic aberrations of gene expression in a rat model of hepatocellular carcinoma	5
Chromatin and transcriptomic profiling uncover dysregulation of the Tip60 HAT/HDAC2 epigenomic landscape in the neurodegenerative brain	5
Feminization of channel catfish with 17β-oestradiol involves methylation and expression of a specific set of genes independent of the sex determination region	5
Digital methylation assessments of alcohol and cigarette consumption account for common variance in accelerated epigenetic ageing	5
CircRNF111 Contributes to Adipocyte Differentiation by Elevating PPARγ Expression via miR-27a-3p	5
DNA hypermethylation/boundary control loss identified in retinoblastomas associated with genetic and epigenetic inactivation of the RB1 gene promoter	5
The influence of obesity on folate status, DNA methylation and cancer-related gene expression in normal breast tissues from premenopausal women	5
Spatiotemporal specificity of correlated DNA methylation and gene expression pairs across different human tissues and stages of brain development	5
Differentially methylated regions (DMRs) in PON3 gene between responders and non-responders to a weight loss dietary intervention: a new tool for precision management of obesity	5
Key changes in chromatin mark mammalian epidermal differentiation and ageing	5
Placental epigenetic gestational aging in relation to maternal sociodemographic factors and smoking among infants born extremely preterm: a descriptive study	5
Placental DNA methylation in pregnancies complicated by maternal diabetes and/or obesity: State of the art and research gaps	5
Weight loss reduces circulating micro-RNA related to obesity and breast cancer in postmenopausal women	5
Age-related epigenetic drift deregulates SIRT6 expression and affects its downstream genes in human peripheral blood mononuclear cells	5
Uncertainty quantification of reference-based cellular deconvolution algorithms	5
Spontaneous and ART-induced large offspring syndrome: similarities and differences in DNA methylome	5
Cross-tolerance: embryonic heat conditioning induces inflammatory resilience by affecting different layers of epigenetic mechanisms regulating IL6 expression later in life	5
LncRNA TUG1 promotes pulmonary fibrosis progression via up-regulating CDC27 and activating PI3K/Akt/mTOR pathway	5
Epigenetic mechanisms underlying the association between maternal climate stress and child growth: characterizing severe drought and its impact on a Kenyan community engaging in a climate change-sensi	4
Impact of glucocorticoids on systemic sirtuin 1 expression and activity in rats with adjuvant-induced arthritis	4
Identification and characterization of extrachromosomal circular DNA in patients with high myopia and cataract	4
Prenatal maternal stress is associated with site-specific and age acceleration changes in maternal and newborn DNA methylation	4
Nitric oxide-related gene and microRNA expression in peripheral blood in pregnancy vary by self-reported race	4
Epigenome-wide association studies of occupational exposure to benzene and formaldehyde	4
Chimpanzee Extraversion scores vary with epigenetic modification of dopamine receptor gene D2 (DRD2) and early rearing conditions	4
The impact of low input DNA on the reliability of DNA methylation as measured by the Illumina Infinium MethylationEPIC BeadChip	4
Ultra-deep whole genome bisulfite sequencing reveals a single methylation hotspot in human brain mitochondrial DNA	4
NMU DNA methylation in blood is associated with metabolic and inflammatory indices: results from the Moli-sani study	4
Exploring the impact of night shift work on methylation of circadian genes	4
Identification of novel susceptibility methylation loci for pancreatic cancer in a two-phase epigenome-wide association study	4
CD4+T-cell DNA methylation changes during pregnancy significantly correlate with disease-associated methylation changes in autoimmune diseases	4
Paradoxical whole genome DNA methylation dynamics of 5’aza-deoxycytidine in chronic low-dose exposure in mice	4
Occupational characteristics and epigenetic aging among older adults in the United States	4
Maternal plasma fatty acid patterns in mid-pregnancy and offspring epigenetic gestational age at birth	4
Histone deacetylase 3 regulates microglial function through histone deacetylation	4
Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the livers of Collaborative Cross mice fed an obesogenic high-fat and high-sucrose diet	4
Context-dependent CpG methylation directs cell-specific binding of transcription factor ZBTB38	4
A comprehensive atlas of epigenetic regulators reveals tissue-specific epigenetic regulation patterns	4
Placental DNA methylation changes in gestational diabetes mellitus	4
Interrelationship between miRNA and splicing factors in pancreatic ductal adenocarcinoma	4
Relationship between redox potential of glutathione and DNA methylation level in liver of newborn guinea pigs	4
Epigenetic Editing in Prostate Cancer: Challenges and Opportunities	4
Roles of adenine methylation and genetic mutations in adaptation to different temperatures in Serratia marcescens	4
Sirtuin1 in vascular endothelial function, an overview	4
Gestational diabetes mellitus placentas exhibit epimutations at placental development genes	4
Dynamics of methylated cell-free DNA in the urine of non-small cell lung cancer patients	4
Alterations in DNA methylation associate with fatty liver and metabolic abnormalities in a multi-ethnic cohort of pre-teenage children	4
Expression of UDP Glucuronosyltransferases 2B15 and 2B17 is associated with methylation status in prostate cancer cells	4
Epigenetic rewiring of pathways related to odour perception in immune cells exposed to SARS-CoV-2in vivoandin vitro	4
Comparing the whole genome methylation landscape of dairy calf blood cells revealed intergenerational inheritance of the maternal metabolism	4
Circ_0078607 increases platinum drug sensitivity via miR-196b-5p/GAS7 axis in ovarian cancer	4