Epigenetics

Article	Citations
Genome-wide CpG density and DNA methylation analysis method (MeDIP, RRBS, and WGBS) comparisons	66
The Socioeconomic Gradient in Epigenetic Ageing Clocks: Evidence from the Multi-Ethnic Study of Atherosclerosis and the Health and Retirement Study	55
Saliva cell type DNA methylation reference panel for epidemiological studies in children	37
Epigenome-wide association study for glyphosate induced transgenerational sperm DNA methylation and histone retention epigenetic biomarkers for disease	32
Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome	31
Genomic map of candidate human imprint control regions: the imprintome	31
DNA methylation profile of genes involved in inflammation and autoimmunity correlates with vascular function in morbidly obese adults	27
Micronutrient supplementation affects transcriptional and epigenetic regulation of lipid metabolism in a dose-dependent manner	26
Comparison of EM-seq and PBAT methylome library methods for low-input DNA	24
Hypermethylation of the oxytocin receptor gene (OXTR) in obsessive-compulsive disorder: further evidence for a biomarker of disease and treatment response	19
Suppressing circIDE/miR-19b-3p/RBMS1 axis exhibits promoting-tumour activity through upregulating GPX4 to diminish ferroptosis in hepatocellular carcinoma	18
m6A RNA demethylase FTO promotes the growth, migration and invasion of pancreatic cancer cells through inhibiting TFPI-2	18
DNA methylation differentiates smoking from vaping and non-combustible tobacco use	18
DNA methylation signatures of adolescent victimization: analysis of a longitudinal monozygotic twin sample	17
Associations between infant sex and DNA methylation across umbilical cord blood, artery, and placenta samples	16
The epigenetics of breast cancer – Opportunities for diagnostics, risk stratification and therapy	16
Early fish domestication affects methylation of key genes involved in the rapid onset of the farmed phenotype	16
Methylomic Signatures of High Grade Serous Ovarian Cancer	16
Tissue and sex-specific programming of DNA methylation by perinatal lead exposure: implications for environmental epigenetics studies	16
Cell-free DNA methylome profiling by MBD-seq with ultra-low input	16
A comparison of epithelial cell content of oral samples estimated using cytology and DNA methylation	15
Extracellular vesicle microRNA in early versus late pregnancy with birth outcomes in the MADRES study	15
Maternal blood metal concentrations and whole blood DNA methylation during pregnancy in the Early Autism Risk Longitudinal Investigation (EARLI)	15
Epigenome-wide analysis of long-term air pollution exposure and DNA methylation in monocytes: results from the Multi-Ethnic Study of Atherosclerosis	15
Exposure to extracellular vesicles from Pseudomonas aeruginosa result in loss of DNA methylation at enhancer and DNase hypersensitive site regions in lung macrophages	14

Overlapping functions of RBBP4 and RBBP7 in regulating cell proliferation and histone H3.3 deposition during mouse preimplantation development	14
DNA methylation changes in glial cells of the normal-appearing white matter in Multiple Sclerosis patients	14
Epigenome-wide scan identifies differentially methylated regions for lung cancer using pre-diagnostic peripheral blood	14
m 6 A-modification regulated circ-CCT3 acts as the sponge of miR-378a-3p to promote hepatocellular carcinoma progression	13
Identification and comparison of m6A modifications in glioblastoma non-coding RNAs with MeRIP-seq and Nanopore dRNA-seq	13
Validation of a DNA methylation microarray for 285,000 CpG sites in the mouse genome	13
DNA methylation as a mediator of associations between the environment and chronic diseases: A scoping review on application of mediation analysis	13
NAT10 mediated mRNA acetylation modification patterns associated with colon cancer progression and microsatellite status	13
Hypermethylation of PI3K-AKT signalling pathway genes is associated with human neural tube defects	13
Cell type-specific chromatin accessibility analysis in the mouse and human brain	13
Methylation of FKBP5 is associated with accelerated DNA methylation ageing and cardiometabolic risk: replication in young-adult and middle-aged Black Americans	12
Effects of substrate modifications on the arginine dimethylation activities of PRMT1 and PRMT5	12
LncRNA TUG1 promotes pulmonary fibrosis progression via up-regulating CDC27 and activating PI3K/Akt/mTOR pathway	12
Dynamic changes in DNA methylation occur in TE regions and affect cell proliferation during leaf-to-callus transition in Arabidopsis	11
Urinary metals and maternal circulating extracellular vesicle microRNA in the MADRES pregnancy cohort	11
Maternal Mediterranean diet in pregnancy and newborn DNA methylation: a meta-analysis in the PACE Consortium	11
Identifying cortical specific long noncoding RNAs modified by m6A RNA methylation in mouse brains	11
Adiposity associated DNA methylation signatures in adolescents are related to leptin and perinatal factors	11
DNA methylome in visceral adipose tissue can discriminate patients with and without colorectal cancer	11
Repurposing epigenetic inhibitors to target the Clostridioides difficile-specific DNA adenine methyltransferase and sporulation regulator CamA	10
NSUN2-mediated RNA m5C modification modulates uveal melanoma cell proliferation and migration	10
Upregulation of polycistronic microRNA-143 and microRNA-145 in colonocytes suppresses colitis and inflammation-associated colon cancer	10
Functional study and epigenetic targets analyses of SIRT1 in intramuscular preadipocytes via ChIP-seq and mRNA-seq	10
Birth weight and maternal energy status during pregnancy as predictors of epigenetic age acceleration in young adults from metropolitan Cebu, Philippines	10
Human non-CpG methylation patterns display both tissue-specific and inter-individual differences suggestive of underlying function	10
RNA modification m 6 Am: the role in cardiac biology	10
Perinatal stress and methylation of the NR3C1 gene in newborns: systematic review	10
Weight loss reduces circulating micro-RNA related to obesity and breast cancer in postmenopausal women	10
The effect of experimental lead pollution on DNA methylation in a wild bird population	10
Prenatal and birth associations of epigenetic gestational age acceleration in the Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS) cohort	9
Sex-based differences in placental DNA methylation profiles related to gestational age: an NIH ECHO meta-analysis	9
Prenatal maternal stress is associated with site-specific and age acceleration changes in maternal and newborn DNA methylation	9
Histone deacetylase 3 regulates microglial function through histone deacetylation	9
A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation	9
DNA methylation ageing clocks and pancreatic cancer risk: pooled analysis of three prospective nested case-control studies	9
Occupational characteristics and epigenetic aging among older adults in the United States	9
Prenatal medication exposure and epigenetic outcomes: a systematic literature review and recommendations for prenatal pharmacoepigenetic studies	9
A methodological pipeline to generate an epigenetic marker of prenatal exposure to air pollution indicators	9
Epigenetic Aging Mediates the Association between Pain Impact and Brain Aging in Middle to Older Age Individuals with Knee Pain	9
Oleic acid-related anti-inflammatory effects in force-stressed PdL fibroblasts are mediated by H3 lysine acetylation associated with altered IL10 expression	9
Tumour suppressor TET2 safeguards enhancers from aberrant DNA methylation and epigenetic reprogramming in ERα-positive breast cancer cells	9
Potential functions of histone H3.3 lysine 56 acetylation in mammals	8
Placental epigenetic gestational aging in relation to maternal sociodemographic factors and smoking among infants born extremely preterm: a descriptive study	8
Feminization of channel catfish with 17β-oestradiol involves methylation and expression of a specific set of genes independent of the sex determination region	8
Uncertainty quantification of reference-based cellular deconvolution algorithms	8
Epigenetic control of the imprinted growth regulator Cdkn1c in cadmium-induced placental dysfunction	8
DNA methylation profiles in pneumonia patients reflect changes in cell types and pneumonia severity	8
Epigenetic mechanisms underlying the association between maternal climate stress and child growth: characterizing severe drought and its impact on a Kenyan community engaging in a climate change-sensi	8
Association between dietary patterns reflecting one-carbon metabolism nutrients intake before pregnancy and placental DNA methylation	8
Circulating miRNAs in the first trimester and pregnancy complications: a systematic review	8

Radiation-induced cardiovascular disease: an overlooked role for DNA methylation?	8
ABCA1, TCF7, NFATC1, PRKCZ, and PDGFA DNA methylation as potential epigenetic-sensitive targets in acute coronary syndrome via network analysis	8
Pharmacoepigenetics of hypertension: genome-wide methylation analysis of responsiveness to four classes of antihypertensive drugs using a double-blind crossover study design	8
Up-regulation of LINC00619 promotes apoptosis and inhibits proliferation, migration and invasion while promoting apoptosis of osteosarcoma cells through inactivation of the HGF-mediated PI3K-Akt signa	8
DNA-methylation for the detection and distinction of 19 human malignancies	8
Spatiotemporal specificity of correlated DNA methylation and gene expression pairs across different human tissues and stages of brain development	8
CircDHRS3 inhibits prostate cancer cell proliferation and metastasis through the circDHRS3/miR-421/MEIS2 axis	8
Identification and characterization of extrachromosomal circular DNA in patients with high myopia and cataract	8
Biological stability of DNA methylation measurements over varying intervals of time and in the presence of acute stress	8
CircRNF111 Contributes to Adipocyte Differentiation by Elevating PPARγ Expression via miR-27a-3p	8
Epigenome-wide association studies of occupational exposure to benzene and formaldehyde	8
Placental DNA methylation in pregnancies complicated by maternal diabetes and/or obesity: State of the art and research gaps	8
Reproducibility of the Infinium methylationEPIC BeadChip assay using low DNA amounts	8
Long non-coding RNA Gm10561 promotes myogenesis by sponging miR-432	8
CD4+T-cell DNA methylation changes during pregnancy significantly correlate with disease-associated methylation changes in autoimmune diseases	7
Roles of adenine methylation and genetic mutations in adaptation to different temperatures in Serratia marcescens	7
Fusaric acid induces hepatic global m6A RNA methylation and differential expression of m6A regulatory genes in vivo - a pilot study	7
Circ_0078607 increases platinum drug sensitivity via miR-196b-5p/GAS7 axis in ovarian cancer	7
Exploring the impact of night shift work on methylation of circadian genes	7
Cumulative stress, PTSD, and emotion dysregulation during pregnancy and epigenetic age acceleration in Hispanic mothers and their newborn infants	7
Key changes in chromatin mark mammalian epidermal differentiation and ageing	7
Updates to data versions and analytic methods influence the reproducibility of results from epigenome-wide association studies	7
Digital methylation assessments of alcohol and cigarette consumption account for common variance in accelerated epigenetic ageing	7
A comprehensive atlas of epigenetic regulators reveals tissue-specific epigenetic regulation patterns	7
Differentially methylated regions (DMRs) in PON3 gene between responders and non-responders to a weight loss dietary intervention: a new tool for precision management of obesity	7
Genome-wide DNA methylation of the liver reveals delayed effects of early-life exposure to 17-α-ethinylestradiol in the self-fertilizing mangrove rivulus	7
Targeted disruption of the histone lysine 79 methyltransferase Dot1L in nephron progenitors causes congenital renal dysplasia	7
Novel DNA methylation loci and genes showing pleiotropic association with Alzheimer’s dementia: a network Mendelian randomization analysis	7
Impact of tobacco, alcohol, and marijuana on genome-wide DNA methylation and its relationship with hypertension	7
Loss of KMT2C reprograms the epigenomic landscape in hPSCs resulting in NODAL overexpression and a failure of hemogenic endothelium specification	7
Epigenome-wide association study and network analysis for IgA Nephropathy from CD19+B-cell in Chinese Population	7
Assessment of aberrant DNA methylation two years after paediatric critical illness: a pre-planned secondary analysis of the international PEPaNIC trial	6
DNA hypermethylation/boundary control loss identified in retinoblastomas associated with genetic and epigenetic inactivation of the RB1 gene promoter	6
Maternal depression and adverse neighbourhood conditions during pregnancy are associated with gestational epigenetic age deceleration	6
Chromatin and transcriptomic profiling uncover dysregulation of the Tip60 HAT/HDAC2 epigenomic landscape in the neurodegenerative brain	6
Epigenetic aberrations of gene expression in a rat model of hepatocellular carcinoma	6
Pruning and thresholding approach for methylation risk scores in multi-ancestry populations	6
Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the livers of Collaborative Cross mice fed an obesogenic high-fat and high-sucrose diet	6
A key regulatory loop AK4P1/miR-375/SP1 in pancreatic adenocarcinoma	6
The impact of low input DNA on the reliability of DNA methylation as measured by the Illumina Infinium MethylationEPIC BeadChip	6
Ultra-deep whole genome bisulfite sequencing reveals a single methylation hotspot in human brain mitochondrial DNA	6
Extracellular microRNA 3’ end modification across diverse body fluids	6
Placental DNA methylation changes in gestational diabetes mellitus	6
Plasma methylated GNB4 and Riplet as a novel dual-marker panel for the detection of hepatocellular carcinoma	6
Prenatal exposure to endocrine disrupting chemicals is associated with altered DNA methylation in cord blood	6
CircCLTH promotes skeletal muscle development and regeneration	6
Epigenetic ageing of the prefrontal cortex and cerebellum in humans and chimpanzees	6
Gestational diabetes mellitus placentas exhibit epimutations at placental development genes	6
Dynamics of methylated cell-free DNA in the urine of non-small cell lung cancer patients	6
Spontaneous and ART-induced large offspring syndrome: similarities and differences in DNA methylome	6
Dietary and supplemental intake of vitamins C and E is associated with altered DNA methylation in an epigenome-wide association study meta-analysis	6
Epigenetic rewiring of pathways related to odour perception in immune cells exposed to SARS-CoV-2in vivoandin vitro	6
Interrelationship between miRNA and splicing factors in pancreatic ductal adenocarcinoma	6
Associations of green and blue space exposure in pregnancy with epigenetic gestational age acceleration	6
Multiple tissue-specific epigenetic alterations regulate persistent gene expression changes following developmental DES exposure in mouse reproductive tissues	6
Proposal of a bioinformatics approach to predict molecular mechanisms involved in inflammatory response: case of ATRA and 1,25(OH) 2 D in adipocytes	6
Whole human genome 5’-mC methylation analysis using long read nanopore sequencing	6
Using Cg05575921 methylation to predict lung cancer risk: a potentially bias-free precision epigenetics approach	6
Context-dependent CpG methylation directs cell-specific binding of transcription factor ZBTB38	6
Alterations in DNA methylation associate with fatty liver and metabolic abnormalities in a multi-ethnic cohort of pre-teenage children	5
Impact of folic acid supplementation on the epigenetic profile in healthy unfortified individuals – a randomized intervention trial	5
Direct bisulphite conversion of cervical samples for DNA methylation analysis	5
Epigenetic targeting of transposon relics: beating the dead horses of the genome?	5
Permutation-based significance analysis reduces the type 1 error rate in bisulphite sequencing data analysis of human umbilical cord blood samples	5
METTL3-mediated m 6 A modification of lnc KCNQ1OT1 promotes doxorubicin resistance in breast cancer by regulating miR-103a-3p/MDR1 axis	5
Nitric oxide-related gene and microRNA expression in peripheral blood in pregnancy vary by self-reported race	5
Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice	5
The effects of age, sex, weight, and breed on canid methylomes	5
A meta-analysis of epigenome-wide association studies on pregnancy vitamin B12 concentrations and offspring DNA methylation	5
Comprehensive analysis of m 6 A methylomes in idiopathic pulmonary arterial hypertension	5
Early-pregnancy maternal body mass index is associated with common DNA methylation markers in cord blood and placenta: a paired-tissue epigenome-wide association study	5
Epigenetic Editing in Prostate Cancer: Challenges and Opportunities	5
Characterization of glucocorticoid-induced loss of DNA methylation of the stress-response gene Fkbp5 in neuronal cells	5
Sirtuin1 in vascular endothelial function, an overview	5
An epigenome-wide analysis of sex hormone levels and DNA methylation in male blood samples	5
The landscape of accessible chromatin in quiescent cardiac fibroblasts and cardiac fibroblasts activated after myocardial infarction	5
Identification of novel susceptibility methylation loci for pancreatic cancer in a two-phase epigenome-wide association study	5
Blood DNA methylation signatures are associated with social determinants of health among survivors of childhood cancer	5
Residential green space in association with the methylation status in a CpG site within the promoter region of the placental serotonin receptor HTR2A	5
DNA methylation signatures in cord blood associated with birthweight are enriched for dmCpGs previously associated with maternal hypertension or pre-eclampsia, smoking and folic acid intake	5

Circ_0003747 promotes thyroid cancer progression by sponging miR-338-3p to upregulate PLCD3 expression	5
Comparative genomic analyses reveal evidence for adaptive A-to-I RNA editing in insect Adar gene	5
Maternal plasma fatty acid patterns in mid-pregnancy and offspring epigenetic gestational age at birth	5
Chimpanzee Extraversion scores vary with epigenetic modification of dopamine receptor gene D2 (DRD2) and early rearing conditions	4
DNA hypermethylation of CADM1, PAX5, WT1, RARβ, and PAX6 genes in oropharyngeal cancer associated with human papillomavirus	4
Sex-specific DNA methylation and associations with in utero tobacco smoke exposure at nuclear-encoded mitochondrial genes	4
An enriched maternal environment and stereotypies of sows differentially affect the neuro-epigenome of brain regions related to emotionality in their piglets	4
To target or not to target? The role of DNA and histone methylation in bacterial infections	4
Comparative and integrative analysis of transcriptomic and epigenomic-wide DNA methylation changes in African American prostate cancer	4
Comparison between indicine and taurine cattle DNA methylation reveals epigenetic variation associated to differences in morphological adaptive traits	4
Comprehensive analysis of transcriptome‐wide M 6 A methylation for hepatic ischaemia reperfusion injury in mice	4
Prenatal lead (Pb) exposure is associated with differential placental DNA methylation and hydroxymethylation in a human population	4
The chromatin remodelling protein LSH/HELLS regulates the amount and distribution of DNA hydroxymethylation in the genome	4
Derivation and investigation of the first human cell-based model of Beckwith-Wiedemann syndrome	4
Temporal genome-wide DNA methylation signature of post-smolt Pacific salmon challenged withPiscirickettsia salmonis	4
Additive and non-additive epigenetic signatures of natural hybridization between fish species with different mating systems	4
Comparing the whole genome methylation landscape of dairy calf blood cells revealed intergenerational inheritance of the maternal metabolism	4
Disease-related blood-based differential methylation in cystic fibrosis and its representation in lung cancer revealed a regulatory locus inPKP3in lung epithelial cells	4
Longitudinal change in blood DNA epigenetic signature after smoking cessation	4
Selenium-associated differentially expressed microRNAs and their targeted mRNAs across the placental genome in two U.S. birth cohorts	4
Perinatal protein malnutrition results in genome-wide disruptions of 5-hydroxymethylcytosine at regions that can be restored to control levels by an enriched environment	4
Brain Tumors: Development, Drug Resistance, and Sensitization – An Epigenetic Approach	4
Ribosomal DNA Copy Number Variation is Coupled with DNA Methylation Changes at the 45S rDNA Locus	4
An evaluation of the genome-wide false positive rates of common methods for identifying differentially methylated regions using illumina methylation arrays	4
m 6 A RNA methylation regulators predict prognosis and indicate characteristics of tumour microenvironment infiltration in acute myeloid leukaemia	4
GPX8 deficiency–induced oxidative stress reprogrammed m6A epitranscriptome of oral cancer cells	4
N6-methyladenosine (m6A) modification in osteosarcoma: expression, function and interaction with noncoding RNAs – an updated review	4
Identification of differentially methylated genes for severe acne by genome-wide DNA methylation and gene expression analysis	4
Maternal haemoglobin levels in pregnancy and child DNA methylation: a study in the pregnancy and childhood epigenetics consortium	4
A region-based method for causal mediation analysis of DNA methylation data	4
FTO promotes proliferation and migration of bladder cancer via enhancing stability of STAT3 mRNA in an m6A-dependent manner	4
Polymethylation scores for prenatal maternal smoke exposure persist until age 15 and are detected in saliva in the Fragile Families and Child Wellbeing cohort	4
DNA hypomethylation mediates immune response in pan-cancer	4
Improving Infinium MethylationEPIC data processing: re-annotation of enhancers and long noncoding RNA genes and benchmarking of normalization methods	4
Sprouty4 is epigenetically upregulated in human colorectal cancer	4
The UHRF1 protein is a key regulator of retrotransposable elements and innate immune response to viral RNA in human cells	4
Arabidopsis thaliana: a powerful model organism to explore histone modifications and their upstream regulations	4
Epigenome wide association study in peripheral blood of pregnant women identifies potential metabolic pathways related to gestational diabetes	3
DNA methylome-based validation of induced sputum as an effective protocol to study lung immunity: construction of a classifier of pulmonary cell types	3
DNA hypermethylation of Kiss1r promoter and reduction of hepatic Kiss1r in female rats with type 2 diabetes	3
Oncogenic DNA methyltransferase 1 activates the PI3K/AKT/mTOR signalling by blocking the binding of HSPB8 and BAG3 in melanoma	3
Cut&tag: a powerful epigenetic tool for chromatin profiling	3
CircRIMKLB promotes myoblast proliferation and inhibits differentiation by sponging miR-29c to release KCNJ12	3
Identification of differential DNA methylation alterations of ovarian cancer in peripheral whole blood based on within-sample relative methylation orderings	3
Differentially methylated regions within lung cancer risk loci are enriched in deregulated enhancers	3
MYCN and HIF-1 directly regulate TET1 expression to control 5-hmC gains and enhance neuroblastoma cell migration in hypoxia	3
Contribution of miR-124 rs531564 polymorphism to the occurrence of congenital Zika syndrome	3
Differential regulation of LRRC37A2 in gastric cancer by DNA methylation	3
In vivo DNA methylation editing in zebrafish	3
NMU DNA methylation in blood is associated with metabolic and inflammatory indices: results from the Moli-sani study	3
Analysis of global DNA methylation and epigenetic modifiers (DNMTs and HDACs) in human foetal endothelium exposed to gestational and type 2 diabetes	3
The role of DNA methylation on gene expression in the vertebrae of ancestrally benzo[a]pyrene exposed F1 and F3 male medaka	3
Differential regulatory roles of microRNAs during intramuscular adipogenesis in Chinese Guizhou Congjiang Xiang pigs	3
ELOVL2-AS1 suppresses tamoxifen resistance by sponging miR-1233-3p in breast cancer	3
Epigenetic changes in pyloric caeca of Atlantic salmon fed diets containing increasing levels of lipids and choline	3
Methylation of tumour suppressor genes in benign and malignant salivary gland tumours: a systematic review and meta-analysis	3
Epigenetic aging in cows is accelerated by milk production	3
Coordinated alternation of DNA methylation and alternative splicing of PBRM1 affect bovine sperm structure and motility	3
mir152hypomethylation as a mechanism for non-syndromic cleft lip and palate	3
Epigenome-wide association study of global cortical volumes in generation Scotland: Scottish family health study	3
Age-associated DNA methylation changes in Xenopus frogs	3
A simple, rapid, interpretable, actionable and implementable digital PCR based mortality index	3
Association of mammographic density with blood DNA methylation	3
Precise epigenomic editing with a SunTag-based modular epigenetic toolkit	3
Memory B-cell like chronic lymphocytic leukaemia is associated with specific methylation profile of WNT5A promoter and undetectable expression of WNT5A gene	3