Epigenetics

Article	Citations
Methylation profiles of global LINE-1 DNA and the GSTP1 promoter region in children exposed to lead (Pb)	69
Digital methylation assessments of alcohol and cigarette consumption account for common variance in accelerated epigenetic ageing	62
Multi-tissue DNA methylation microarray signature is predictive of gene function	37
Cell type-specific chromatin accessibility analysis in the mouse and human brain	31
Placental DNA methylation in pregnancies complicated by maternal diabetes and/or obesity: State of the art and research gaps	31
DNA methylome and transcriptome profiling reveal key electrophysiology and immune dysregulation in hypertrophic cardiomyopathy	24
Impact of testicular cancer on sperm small non-coding RNA signature: a pilot study	19
Leukocyte DNA methylation in Alzheimer´s disease associated genes: replication of findings from neuronal cells	19
Pharmacoepigenetics of hypertension: genome-wide methylation analysis of responsiveness to four classes of antihypertensive drugs using a double-blind crossover study design	19
Disentangling tumorigenesis-associated DNA methylation changes in colorectal tissues from those associated with ageing	18
Dynamics of methylated cell-free DNA in the urine of non-small cell lung cancer patients	18
A key regulatory loop AK4P1/miR-375/SP1 in pancreatic adenocarcinoma	18
Epigenetic control of the imprinted growth regulator Cdkn1c in cadmium-induced placental dysfunction	16
Urinary metals and maternal circulating extracellular vesicle microRNA in the MADRES pregnancy cohort	16
DNA methylome-based validation of induced sputum as an effective protocol to study lung immunity: construction of a classifier of pulmonary cell types	15
Sex-specific DNA methylation and transcription of zbtb38 and effects of gene–environment interactions on its natural antisense transcript in zebrafish	15
Overlapping functions of RBBP4 and RBBP7 in regulating cell proliferation and histone H3.3 deposition during mouse preimplantation development	15
GPX8 deficiency–induced oxidative stress reprogrammed m6A epitranscriptome of oral cancer cells	15
Coordinated alternation of DNA methylation and alternative splicing of PBRM1 affect bovine sperm structure and motility	14
Dominant effects of the histone mutant H3-L61R on Spt16-gene interactions in budding yeast	14
Using Cg05575921 methylation to predict lung cancer risk: a potentially bias-free precision epigenetics approach	14
Epigenetic age acceleration, neonatal morbidities, and neurobehavioral profiles in infants born very preterm	14
Maternal plasma fatty acid patterns in mid-pregnancy and offspring epigenetic gestational age at birth	14
NSUN2-mediated RNA m5C modification modulates uveal melanoma cell proliferation and migration	13
Gestational diabetes mellitus placentas exhibit epimutations at placental development genes	13

Histone deacetylase 3 regulates microglial function through histone deacetylation	13
Tumour suppressor TET2 safeguards enhancers from aberrant DNA methylation and epigenetic reprogramming in ERα-positive breast cancer cells	13
Prenatal medication exposure and epigenetic outcomes: a systematic literature review and recommendations for prenatal pharmacoepigenetic studies	13
Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the livers of Collaborative Cross mice fed an obesogenic high-fat and high-sucrose diet	13
Epigenome-wide association studies of occupational exposure to benzene and formaldehyde	12
Differential regulation of LRRC37A2 in gastric cancer by DNA methylation	12
Co-occurrence of injection drug use and hepatitis C increases epigenetic age acceleration that contributes to all-cause mortality among people living with HIV	11
Human non-CpG methylation patterns display both tissue-specific and inter-individual differences suggestive of underlying function	11
Whole human genome 5’-mC methylation analysis using long read nanopore sequencing	11
Epigenome wide association study in peripheral blood of pregnant women identifies potential metabolic pathways related to gestational diabetes	11
In silico identification and in vitro expression analysis of breast cancer-related m6A-SNPs	10
IL-18 serves as a main effector of CAF-derived METTL3 against immunosuppression of NSCLC via driving NF-κB pathway	10
Genome-wide CpG density and DNA methylation analysis method (MeDIP, RRBS, and WGBS) comparisons	10
Chimpanzee Extraversion scores vary with epigenetic modification of dopamine receptor gene D2 (DRD2) and early rearing conditions	10
In vivo DNA methylation editing in zebrafish	10
Fusaric acid induces hepatic global m6A RNA methylation and differential expression of m6A regulatory genes in vivo - a pilot study	10
Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice	10
Clinical significance of peripheral blood DDR1 and CtBP gene methylation detection in patients with acute pancreatitis	10
Using methylation data to improve transcription factor binding prediction	9
IL21R hypomethylation as a biomarker for distinguishing benign and malignant breast tumours	9
Role of N6-methyladenosine-related lncRnas in pseudoexfoliation glaucoma	9
Epigenetic landscape of 5-hydroxymethylcytosine and associations with gene expression in placenta	9
DNA methylation markers for risk of metastasis in a cohort of men with localized prostate cancer	9
N6-methyladenosine methylation analysis of long noncoding RNAs and mRNAs in 5-FU-resistant colon cancer cells	9
Letter to the editor: critical evaluation of the reliability of DNA methylation probes on the illumina MethylationEPIC v1.0 BeadChip microarrays	9
Correction	9
m6A reader YTHDC2 mediates NCOA4 mRNA stability affecting ferritinophagy to alleviate secondary injury after intracerebral haemorrhage	9
Identification and functional characterisation of DNA methylation differences between East- and West-originating Finns	8
GGNBP2 regulates histone ubiquitination and methylation in spermatogenesis	8
Epigenetic ageing of the prefrontal cortex and cerebellum in humans and chimpanzees	8
Long-range chromosomal interactions increase and mark repressed gene expression during adipogenesis	8
Hypermethylation of the oxytocin receptor gene (OXTR) in obsessive-compulsive disorder: further evidence for a biomarker of disease and treatment response	8
Novel DNA methylation loci and genes showing pleiotropic association with Alzheimer’s dementia: a network Mendelian randomization analysis	8
Sirtuin1 in vascular endothelial function, an overview	8
A newly identified lncRNA lnc000100 regulates proliferation and differentiation of cattle skeletal muscle cells	8
Vitamin C enhances co-localization of novel TET1 nuclear bodies with both Cajal and PML bodies in colorectal cancer cells	8
An epigenome-wide analysis of sex hormone levels and DNA methylation in male blood samples	8
TET1 inhibits the migration and invasion of cervical cancer cells by regulating autophagy	8
Epigenome-wide association study of long-term psychosocial stress in older adults	8
Weight loss reduces circulating micro-RNA related to obesity and breast cancer in postmenopausal women	8
Association of DNA methylation signatures with premature ageing and cardiovascular death in patients with end-stage kidney disease: a pilot epigenome-wide association study	8
ABCA1, TCF7, NFATC1, PRKCZ, and PDGFA DNA methylation as potential epigenetic-sensitive targets in acute coronary syndrome via network analysis	8
Comparative genomic analyses reveal evidence for adaptive A-to-I RNA editing in insect Adar gene	8
Epigenetic aging of semen is associated with inflammation	8
Animal and plant protein intake during infancy and childhood DNA methylation: a meta-analysis in the NutriPROGRAM consortium	8
Genetic architecture of epigenetic cortical clock age in brain tissue from older individuals: alterations in CD46 and other loci	8
Evaluating DNA recovery efficiency following bisulphite modification from plasma samples submitted for cell-free DNA methylation analysis	8
The influence of intergenerational trauma on epigenetics and obesity in Indigenous populations - a scoping review	8
Crosstalk between m6A mRNAs and m6A circRNAs and the time-specific biogenesis of m6A circRNAs after OGD/R in primary neurons	8
Occupational characteristics and epigenetic aging among older adults in the United States	8

Methylome profile of medaka eggs and sperm	7
An epigenetic human cytomegalovirus infection score predicts viremia risk in seropositive lung transplant recipients	7
Resistance and aerobic training increases genome-wide DNA methylation in women with polycystic ovary syndrome	7
Genetic confounds of transgenerational epigenetic inheritance in mice	7
Generational stability of epigenetic transgenerational inheritance facilitates adaptation and evolution	7
Transgenerational epigenetic self-memory of Dio3 dosage is associated with Meg3 methylation and altered growth trajectories and neonatal h	7
ANRIL upregulates TGFBR1 to promote idiopathic pulmonary fibrosis in TGF-β1-treated lung fibroblasts via sequestering let-7d-5p	7
MicroRNA-185-5p: a marker of brain-sparing in foetuses with late-onset growth restriction	7
Nitric oxide-related gene and microRNA expression in peripheral blood in pregnancy vary by self-reported race	7
A promising application of kidney-specific cell-free DNA methylation markers in real-time monitoring sepsis-induced acute kidney injury	7
Detailed immune profiling in pediatric Crohn’s disease using methylation cytometry	7
Prenatal Socioeconomic Disadvantage and Epigenetic Alterations at Birth Among Children Born to White British and Pakistani Mothers in the Born in Bradford Study	7
Homocysteine affects macrophage polarization by altering m6A methylation of scavenger receptors CD209 and CD163L1	7
Evaluation of methylated DCR1 as a biomarker for response to adjuvant irinotecan-based therapy in stage III colon cancer: cancer and leukaemia Group B 89803 (Alliance)	7
One-carbon metabolism nutrients impact the interplay between DNA methylation and gene expression in liver, enhancing protein synthesis in Atlantic salmon	7
YY1/circCTNNB1/miR-186-5p/YY1 positive loop aggravates lung cancer progression through the Wnt pathway	7
Detection of DNA methylation from buccal swabs using nanopore sequencing to study stunting	7
Evaluating the utility of ZNF331 promoter methylation as a prognostic and predictive marker in stage III colon cancer: results from CALGB 89803 (Alliance)	7
Birth weight and maternal energy status during pregnancy as predictors of epigenetic age acceleration in young adults from metropolitan Cebu, Philippines	6
Pruning and thresholding approach for methylation risk scores in multi-ancestry populations	6
Histone demethylase KDM4B contributes to advanced clear cell renal carcinoma and association with copy number variations and cell cycle progression	6
Uncertainty quantification of reference-based cellular deconvolution algorithms	6
Differential methylation pattern in pubertal girls associated with biochemical premature adrenarche	6
Prenatal maternal stress is associated with site-specific and age acceleration changes in maternal and newborn DNA methylation	6
ZNF143 inhibits hepatocyte mitophagy and promotes non-alcoholic fatty liver disease by targeting increased lncRNA NEAT1 expression to activate ROCK2 pathway	6
Roles of adenine methylation and genetic mutations in adaptation to different temperatures in Serratia marcescens	6
Epigenome-wide analysis of long-term air pollution exposure and DNA methylation in monocytes: results from the Multi-Ethnic Study of Atherosclerosis	6
Proposal of a bioinformatics approach to predict molecular mechanisms involved in inflammatory response: case of ATRA and 1,25(OH) 2 D in adipocytes	6
m 6 A RNA methylation regulators predict prognosis and indicate characteristics of tumour microenvironment infiltration in acute myeloid leukaemia	6
Suppressing circIDE/miR-19b-3p/RBMS1 axis exhibits promoting-tumour activity through upregulating GPX4 to diminish ferroptosis in hepatocellular carcinoma	6
Updates to data versions and analytic methods influence the reproducibility of results from epigenome-wide association studies	6
Domain architecture and protein–protein interactions regulate KDM5A recruitment to the chromatin	6
Arabidopsis thaliana: a powerful model organism to explore histone modifications and their upstream regulations	6
Saliva cell type DNA methylation reference panel for epidemiological studies in children	6
The Socioeconomic Gradient in Epigenetic Ageing Clocks: Evidence from the Multi-Ethnic Study of Atherosclerosis and the Health and Retirement Study	6
Deciphering the interplay between SETD2 mediated H3K36me3 and RNA N6-methyladenosine in clear cell renal cell carcinoma (ccRCC)	6
A comparison of epithelial cell content of oral samples estimated using cytology and DNA methylation	6
Maternal blood metal concentrations and whole blood DNA methylation during pregnancy in the Early Autism Risk Longitudinal Investigation (EARLI)	6
Multiomics analysis of adaptation to repeated DNA damage in prostate cancer cells	6
Epigenetic aging in cows is accelerated by milk production	6
Aberrant regulation of CXCR4 in cancer via deviant microRNA-targeted interactions	6
Targeted epigenetic silencing of UCHL1 expression suppresses collagen-1 production in human lung epithelial cells	6
A novel principal component based method for identifying differentially methylated regions in Illumina Infinium MethylationEPIC BeadChip data	6
CircRNF111 Contributes to Adipocyte Differentiation by Elevating PPARγ Expression via miR-27a-3p	6
A plant-based diet differentially affects the global hepatic methylome in rainbow trout depending on genetic background	6
Oleic acid-related anti-inflammatory effects in force-stressed PdL fibroblasts are mediated by H3 lysine acetylation associated with altered IL10 expression	6
An investigation into DNA methylation patterns associated with risk preference in older individuals	6
Contribution of miR-124 rs531564 polymorphism to the occurrence of congenital Zika syndrome	6
Methylation of tumour suppressor genes in benign and malignant salivary gland tumours: a systematic review and meta-analysis	5
Identification cloning and functional analysis of novel natural antisense lncRNA CFL1-AS1 in cattle	5
Repurposing epigenetic inhibitors to target the Clostridioides difficile-specific DNA adenine methyltransferase and sporulation regulator CamA	5
Circulating miRNAs in the first trimester and pregnancy complications: a systematic review	5
Genetic and epigenetic analysis of the serotonin 2A receptor in the context of cocaine abuse	5
Precise epigenomic editing with a SunTag-based modular epigenetic toolkit	5
DNA methylation signatures in cord blood associated with birthweight are enriched for dmCpGs previously associated with maternal hypertension or pre-eclampsia, smoking and folic acid intake	5
Exercise effects on DNA methylation in EVL, CDKN2A (p14, ARF), and ESR1 in colon tissue from healthy men and women	5
Does genetic predisposition modify the effect of lifestyle-related factors on DNA methylation?	5
Comparison of EM-seq and PBAT methylome library methods for low-input DNA	5
Analysis of genome-wide 5-hydroxymethylation of blood samples stored in different anticoagulants: opportunities for the expansion of clinical resources for epigenetic research	5
DNA methylome in visceral adipose tissue can discriminate patients with and without colorectal cancer	5
Examination of newborn DNA methylation among women with polycystic ovary syndrome/hirsutism	5
CircCLTH promotes skeletal muscle development and regeneration	5
The chromatin remodelling protein LSH/HELLS regulates the amount and distribution of DNA hydroxymethylation in the genome	5
Brain Tumors: Development, Drug Resistance, and Sensitization – An Epigenetic Approach	5
DNA methylation biomarkers to identify epigenetically abnormal spermatozoa in male partners from couples experiencing recurrent pregnancy loss	5
Time-course full profiling of circulating miRNAs in neurologically deceased organ donors: a proof of concept study to understand the onset of the cytokine storm	5
An evaluation of the genome-wide false positive rates of common methods for identifying differentially methylated regions using illumina methylation arrays	5
Methylation patterns associated with C-reactive protein in racially and ethnically diverse populations	4
Epigenome-wide association study of perceived discrimination in the Multi-Ethnic Study of Atherosclerosis (MESA)	4
Exploring fatty acids from royal jelly as a source of histone deacetylase inhibitors: from the hive to applications in human well-being and health	4
Circ-0006332 stimulates cardiomyocyte pyroptosis via the miR-143/TLR2 axis to promote doxorubicin-induced cardiac damage	4
Biogenesis of circRBM33 mediated by N6-methyladenosine and its function in abdominal aortic aneurysm	4
Memory B-cell like chronic lymphocytic leukaemia is associated with specific methylation profile of WNT5A promoter and undetectable expression of WNT5A gene	4
Feminization of channel catfish with 17β-oestradiol involves methylation and expression of a specific set of genes independent of the sex determination region	4
Accelerated epigenetic age at birth and child emotional and behavioural development in early childhood: a meta-analysis of four prospective cohort studies in ECHO	4
MYCN and HIF-1 directly regulate TET1 expression to control 5-hmC gains and enhance neuroblastoma cell migration in hypoxia	4
A consistent pattern of slide effects in Illumina DNA methylation BeadChip array data	4
Genomic context determines the effect of DNA methylation on gene expression in the gut epithelium of Atlantic salmon ( Salmo salar )	4
Transmission of reduced levels of miR-34/449 from sperm to preimplantation embryos is a key step in the transgenerational epigenetic inheritance of the effects of paternal chronic social instability s	4
Widespread genomic de novo DNA methylation occurs following CD8 + T cell activation and proliferation	4

Non-coding 886 ( nc886 / vtRNA2-1 ), the epigenetic odd duck – implications for future studies	4
History of exposure to copper influences transgenerational gene expression responses in Daphnia magna	4
Circ_0003747 promotes thyroid cancer progression by sponging miR-338-3p to upregulate PLCD3 expression	4
Sprouty4 is epigenetically upregulated in human colorectal cancer	4
Epigenetic Aging Mediates the Association between Pain Impact and Brain Aging in Middle to Older Age Individuals with Knee Pain	4
Ribosomal DNA Copy Number Variation is Coupled with DNA Methylation Changes at the 45S rDNA Locus	4
Identification and characterization of extrachromosomal circular DNA in patients with high myopia and cataract	4
Stress-induced epigenetic effects driven by maternal lactation in dairy cattle: a comethylation network approach	4
PRKCB methylation: a potential biomarker of MDD with childhood chronic stress, a cross-sectional study in drug-naive, first-episode adolescent MDD	4
METTL3-mediated m 6 A modification of lnc KCNQ1OT1 promotes doxorubicin resistance in breast cancer by regulating miR-103a-3p/MDR1 axis	4
Correction	4
Epigenome-wide association study of loneliness in a sample of U.S. middle-aged twins	4
The UHRF1 protein is a key regulator of retrotransposable elements and innate immune response to viral RNA in human cells	4
Prenatal lead (Pb) exposure is associated with differential placental DNA methylation and hydroxymethylation in a human population	4
Extracellular vesicle microRNA in early versus late pregnancy with birth outcomes in the MADRES study	4
Epigenetic changes in pyloric caeca of Atlantic salmon fed diets containing increasing levels of lipids and choline	4
Pleiotropic influence of DNA methylation QTLs on physiological and ageing traits	3
Exploration of genome-wide DNA methylation profiles in night shift workers	3
Epigenetic aberrations of gene expression in a rat model of hepatocellular carcinoma	3
Non-pathogenic microbiota accelerate age-related CpG Island methylation in colonic mucosa	3
DNA methylation differentiates smoking from vaping and non-combustible tobacco use	3
Differentially methylated regions within lung cancer risk loci are enriched in deregulated enhancers	3
Pan-precancer and cancer DNA methylation profiles revealed significant tissue specificity of interrupted biological processes in tumorigenesis	3
Placental epigenetic gestational aging in relation to maternal sociodemographic factors and smoking among infants born extremely preterm: a descriptive study	3
Chromatin and transcriptomic profiling uncover dysregulation of the Tip60 HAT/HDAC2 epigenomic landscape in the neurodegenerative brain	3
LncRNA NEAT1 promotes IL-6 secretion in monocyte-derived dendritic cells via sponging miR-365a-3p in systemic lupus erythematosus	3
DNA methylation and gene expression changes in mouse mammary tissue during successive lactations: part II – the impact of lactation rank	3
Phenotypic and transcriptomic impact of expressing mammalian TET2 in theDrosophila melanogastermodel	3
ELOVL2-AS1 suppresses tamoxifen resistance by sponging miR-1233-3p in breast cancer	3
Comparison of global DNA methylation analysis by whole genome bisulfite sequencing and the Infinium Mouse Methylation BeadChip using fresh and fresh-frozen mouse epidermis	3
Catalytic domain-dependent and -independent transcriptional activities of the tumour suppressor histone H3K27 demethylase UTX/KDM6A in specific cancer types	3
Association of mammographic density with blood DNA methylation	3
Intergenerational effects of early life-stage temperature modulation on gene expression and DNA methylation in Atlantic cod ( Gadus morhua )	3
Prenatal exposure to endocrine disrupting chemicals is associated with altered DNA methylation in cord blood	3
Regulatory networks of circRNA- centred ceRNAs in sepsis-induced acute kidney injury	3
Epimutation detection in the clinical context: guidelines and a use case from a new Bioconductor package	3
MYOD induced lnc-MEG3 promotes porcine satellite cell differentiation via interacting with DLST	3
Improving Infinium MethylationEPIC data processing: re-annotation of enhancers and long noncoding RNA genes and benchmarking of normalization methods	3
Epigenetic Editing in Prostate Cancer: Challenges and Opportunities	3
Sex-based differences in placental DNA methylation profiles related to gestational age: an NIH ECHO meta-analysis	3
DNA methylation as a mediator of associations between the environment and chronic diseases: A scoping review on application of mediation analysis	3
An IDH-independent mechanism of DNA hypermethylation upon VHL inactivation in cancer	3
Multiple tissue-specific epigenetic alterations regulate persistent gene expression changes following developmental DES exposure in mouse reproductive tissues	3