Epigenetics

Article	Citations
Leukocyte DNA methylation in Alzheimer´s disease associated genes: replication of findings from neuronal cells	84
Disentangling tumorigenesis-associated DNA methylation changes in colorectal tissues from those associated with ageing	73
Epigenetic landscape of 5-hydroxymethylcytosine and associations with gene expression in placenta	60
Digital methylation assessments of alcohol and cigarette consumption account for common variance in accelerated epigenetic ageing	41
Placental DNA methylation in pregnancies complicated by maternal diabetes and/or obesity: State of the art and research gaps	31
Identification and functional characterisation of DNA methylation differences between East- and West-originating Finns	29
Role of N6-methyladenosine-related lncRnas in pseudoexfoliation glaucoma	26
Using methylation data to improve transcription factor binding prediction	23
GGNBP2 regulates histone ubiquitination and methylation in spermatogenesis	23
Co-occurrence of injection drug use and hepatitis C increases epigenetic age acceleration that contributes to all-cause mortality among people living with HIV	22
The influence of intergenerational trauma on epigenetics and obesity in Indigenous populations - a scoping review	21
N6-methyladenosine methylation analysis of long noncoding RNAs and mRNAs in 5-FU-resistant colon cancer cells	21
Generational stability of epigenetic transgenerational inheritance facilitates adaptation and evolution	20
Detailed immune profiling in pediatric Crohn’s disease using methylation cytometry	20
Differential methylation pattern in pubertal girls associated with biochemical premature adrenarche	19
Proposal of a bioinformatics approach to predict molecular mechanisms involved in inflammatory response: case of ATRA and 1,25(OH) 2 D in adipocytes	19
Multiomics analysis of adaptation to repeated DNA damage in prostate cancer cells	18
Roles of adenine methylation and genetic mutations in adaptation to different temperatures in Serratia marcescens	18
CircRNF111 Contributes to Adipocyte Differentiation by Elevating PPARγ Expression via miR-27a-3p	17
The Socioeconomic Gradient in Epigenetic Ageing Clocks: Evidence from the Multi-Ethnic Study of Atherosclerosis and the Health and Retirement Study	17
Placental malaria induces a unique methylation profile associated with fetal growth restriction	17
Identification cloning and functional analysis of novel natural antisense lncRNA CFL1-AS1 in cattle	17
DNA methylome in visceral adipose tissue can discriminate patients with and without colorectal cancer	16
The UHRF1 protein is a key regulator of retrotransposable elements and innate immune response to viral RNA in human cells	16
Identification and characterization of extrachromosomal circular DNA in patients with high myopia and cataract	16

MYCN and HIF-1 directly regulate TET1 expression to control 5-hmC gains and enhance neuroblastoma cell migration in hypoxia	15
Repurposing epigenetic inhibitors to target the Clostridioides difficile-specific DNA adenine methyltransferase and sporulation regulator CamA	15
Acetaldehyde-driven mRNA methylation and expression changes in ethanol-metabolizing enzyme genes	15
Accelerated epigenetic age at birth and child emotional and behavioural development in early childhood: a meta-analysis of four prospective cohort studies in ECHO	15
Genomic context determines the effect of DNA methylation on gene expression in the gut epithelium of Atlantic salmon ( Salmo salar )	14
Regulatory networks of circRNA- centred ceRNAs in sepsis-induced acute kidney injury	13
Placental and immune cell DNA methylation reference panel for bulk tissue cell composition estimation in epidemiological studies	13
Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome	13
Direction-aware functional class scoring enrichment analysis of infinium DNA methylation data	13
Pan-precancer and cancer DNA methylation profiles revealed significant tissue specificity of interrupted biological processes in tumorigenesis	13
ELOVL2-AS1 suppresses tamoxifen resistance by sponging miR-1233-3p in breast cancer	13
Selenium-associated differentially expressed microRNAs and their targeted mRNAs across the placental genome in two U.S. birth cohorts	13
Epigenome-wide association study of loneliness in a sample of U.S. middle-aged twins	13
Polymethylation scores for prenatal maternal smoke exposure persist until age 15 and are detected in saliva in the Fragile Families and Child Wellbeing cohort	13
The role of DNA methylation on gene expression in the vertebrae of ancestrally benzo[a]pyrene exposed F1 and F3 male medaka	12
Comprehensive analysis of m 6 A methylomes in idiopathic pulmonary arterial hypertension	12
Long non-coding RNA Gm10561 promotes myogenesis by sponging miR-432	12
Direct bisulphite conversion of cervical samples for DNA methylation analysis	12
Interrelationship between miRNA and splicing factors in pancreatic ductal adenocarcinoma	12
Integration of miRNA expression analysis of purified leukocytes and whole blood reveals blood-borne candidate biomarkers for lung cancer	12
CircRIMKLB promotes myoblast proliferation and inhibits differentiation by sponging miR-29c to release KCNJ12	11
Chemotherapy-induced acceleration of DNA methylation-based biological age in breast cancer	11
Large-scale integration of DNA methylation and gene expression array platforms identifies both cis and trans relationships	11
Cumulative stress, PTSD, and emotion dysregulation during pregnancy and epigenetic age acceleration in Hispanic mothers and their newborn infants	11
Associations between infant sex and DNA methylation across umbilical cord blood, artery, and placenta samples	11
Upregulation of KHDC1L promotes the proliferation and inhibits apoptosis in head and neck squamous cell carcinoma	11
Blood DNA methylation signatures are associated with social determinants of health among survivors of childhood cancer	11
Timing of dietary effects on the epigenome and their potential protective effects against toxins	11
The one-carbon metabolism as an underlying pathway for placental DNA methylation – a systematic review	11
Gaps in current methods to detect polymorphic CpGs from Illumina Infinium human methylation microarrays and exploring their potential impact in multi-EWAS analyses	10
mir152hypomethylation as a mechanism for non-syndromic cleft lip and palate	10
Hypomethylation at H19DMR in penile squamous cell carcinoma is not related to HPV infection	10
DNA methylation changes in glial cells of the normal-appearing white matter in Multiple Sclerosis patients	10
Biological stability of DNA methylation measurements over varying intervals of time and in the presence of acute stress	10
ΔNp63α-mediated epigenetic regulation in keratinocyte senescence	10
Upregulation of GPR133 expression impaired the phagocytosis of macrophages in recurrent spontaneous miscarriage	10
Heavy alcohol consumption but not smoking predicts mortality in patients with acute coronary syndrome	10
DNA-based cell typing in menstrual effluent identifies cell type variation by sample collection method: toward noninvasive biomarker development for women’s health	10
DNA methylation at birth and fine motor ability in childhood: an epigenome-wide association study with replication	10
Cut&tag: a powerful epigenetic tool for chromatin profiling	10
Detecting aberrant DNA methylation in Illumina DNA methylation arrays: a toolbox and recommendations for its use	10
Study on chromatin regulation patterns of expression vectors in the PhiC31 integration site	10
DNMT1 expression partially dictates 5-Azacytidine sensitivity and correlates with RAS/MEK/ERK activity in gastric cancer cells	10
Alterations in DNA methylation associate with fatty liver and metabolic abnormalities in a multi-ethnic cohort of pre-teenage children	10
Dynamics of methylated cell-free DNA in the urine of non-small cell lung cancer patients	9
DNA methylation profiles in bovine sperm are associated with daughter fertility	9
Dietary and supplemental intake of vitamins C and E is associated with altered DNA methylation in an epigenome-wide association study meta-analysis	9
Analysis of global DNA methylation and epigenetic modifiers (DNMTs and HDACs) in human foetal endothelium exposed to gestational and type 2 diabetes	9
Assessment of aberrant DNA methylation two years after paediatric critical illness: a pre-planned secondary analysis of the international PEPaNIC trial	9
Comparative genomic analyses reveal evidence for adaptive A-to-I RNA editing in insect Adar gene	9

RNA modification m 6 Am: the role in cardiac biology	9
Methylome profile of medaka eggs and sperm	8
Domain architecture and protein–protein interactions regulate KDM5A recruitment to the chromatin	8
m6A reader YTHDC2 mediates NCOA4 mRNA stability affecting ferritinophagy to alleviate secondary injury after intracerebral haemorrhage	8
NSUN2-mediated RNA m5C modification modulates uveal melanoma cell proliferation and migration	8
Higher sperm H3K4me3 levels are associated with idiopathic recurrent pregnancy loss	8
Time-course full profiling of circulating miRNAs in neurologically deceased organ donors: a proof of concept study to understand the onset of the cytokine storm	8
Memory B-cell like chronic lymphocytic leukaemia is associated with specific methylation profile of WNT5A promoter and undetectable expression of WNT5A gene	8
Prenatal Socioeconomic Disadvantage and Epigenetic Alterations at Birth Among Children Born to White British and Pakistani Mothers in the Born in Bradford Study	8
Detection of DNA methylation from buccal swabs using nanopore sequencing to study stunting	8
Epigenetic age acceleration, neonatal morbidities, and neurobehavioral profiles in infants born very preterm	8
A novel principal component based method for identifying differentially methylated regions in Illumina Infinium MethylationEPIC BeadChip data	8
Comparison of EM-seq and PBAT methylome library methods for low-input DNA	8
History of exposure to copper influences transgenerational gene expression responses in Daphnia magna	8
Uncertainty quantification of reference-based cellular deconvolution algorithms	8
Sirtuin1 in vascular endothelial function, an overview	8
Genome-wide CpG density and DNA methylation analysis method (MeDIP, RRBS, and WGBS) comparisons	8
Epigenome wide association study in peripheral blood of pregnant women identifies potential metabolic pathways related to gestational diabetes	8
Novel DNA methylation loci and genes showing pleiotropic association with Alzheimer’s dementia: a network Mendelian randomization analysis	8
Precise epigenomic editing with a SunTag-based modular epigenetic toolkit	8
Oleic acid-related anti-inflammatory effects in force-stressed PdL fibroblasts are mediated by H3 lysine acetylation associated with altered IL10 expression	8
Stress-induced epigenetic effects driven by maternal lactation in dairy cattle: a comethylation network approach	8
Spontaneous and ART-induced large offspring syndrome: similarities and differences in DNA methylome	7
Genome-wide DNA methylation of the liver reveals delayed effects of early-life exposure to 17-α-ethinylestradiol in the self-fertilizing mangrove rivulus	7
Methylation of FKBP5 is associated with accelerated DNA methylation ageing and cardiometabolic risk: replication in young-adult and middle-aged Black Americans	7
Comprehensive analysis of transcriptome‐wide M 6 A methylation for hepatic ischaemia reperfusion injury in mice	7
Catalytic domain-dependent and -independent transcriptional activities of the tumour suppressor histone H3K27 demethylase UTX/KDM6A in specific cancer types	7
Dose rate dependent reduction in chromatin accessibility at transcriptional start sites long time after exposure to gamma radiation	7
Epigenome-wide meta-analysis of prenatal vitamin D insufficiency and cord blood DNA methylation	7
Sex and tissue-specificity of piRNA regulation in adult mice following perinatal lead (Pb) exposure	7
Combined exercise training decreases blood pressure in OLDER women with NOS3 polymorphism providing changes in differentially methylated regions (DMRs)	7
Implementation of the Methyl-Seq platform to identify tissue- and sex-specific DNA methylation differences in the rat epigenome	7
m6A RNA demethylase FTO promotes the growth, migration and invasion of pancreatic cancer cells through inhibiting TFPI-2	7
Decoding epigenetic markers: implications of traits and genes through DNA methylation in resilience and susceptibility to mastitis in dairy cows	7
Glucocorticoid receptor epigenetic activity in the heart	7
Genome-wide methylation analysis in patients with proximal hypospadias – a pilot study and review of the literature	7
Sex-based differences in placental DNA methylation profiles related to gestational age: an NIH ECHO meta-analysis	7
Genetic and epigenetic analysis of the serotonin 2A receptor in the context of cocaine abuse	7
Circ_0003747 promotes thyroid cancer progression by sponging miR-338-3p to upregulate PLCD3 expression	7
Plasma methylated GNB4 and Riplet as a novel dual-marker panel for the detection of hepatocellular carcinoma	7
DNA hypermethylation of CADM1, PAX5, WT1, RARβ, and PAX6 genes in oropharyngeal cancer associated with human papillomavirus	7
Identification of differentially methylated genes for severe acne by genome-wide DNA methylation and gene expression analysis	7
Maternal adverse childhood experiences (ACEs) and offspring imprinted gene DMR methylation at birth	7
Genome wide exploration of the methylome in aggressive B-cell lymphoma in Golden Retrievers reveals a conserved hypermethylome	7
Epigenetic targeting of transposon relics: beating the dead horses of the genome?	7
Comparative and integrative analysis of transcriptomic and epigenomic-wide DNA methylation changes in African American prostate cancer	7
Anthropometric, biochemical, and haematological indicators associated with hyperhomocysteinemia and their relation to global DNA methylation in a young adult population	7
DNA methylation biomarkers to identify epigenetically abnormal spermatozoa in male partners from couples experiencing recurrent pregnancy loss	7
Parental arsenic exposure and tissue-specific DNA methylation in Bangladeshi infants with spina bifida	7
Imprinted gene alterations in the kidneys of growth restricted offspring may be mediated by a long non-coding RNA	7
MK-801-exposure induces increased translation efficiency and mRNA hyperacetylation of Grin2a in the mouse prefrontal cortex	7
Targeted epigenetic silencing of UCHL1 expression suppresses collagen-1 production in human lung epithelial cells	6
m 6 A RNA methylation regulators predict prognosis and indicate characteristics of tumour microenvironment infiltration in acute myeloid leukaemia	6
YY1/circCTNNB1/miR-186-5p/YY1 positive loop aggravates lung cancer progression through the Wnt pathway	6
IL21R hypomethylation as a biomarker for distinguishing benign and malignant breast tumours	6
Sex-specific DNA methylation and associations with in utero tobacco smoke exposure at nuclear-encoded mitochondrial genes	6
Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the livers of Collaborative Cross mice fed an obesogenic high-fat and high-sucrose diet	6
Letter to the editor: critical evaluation of the reliability of DNA methylation probes on the illumina MethylationEPIC v1.0 BeadChip microarrays	6
Epigenetic ageing of the prefrontal cortex and cerebellum in humans and chimpanzees	6
In silico identification and in vitro expression analysis of breast cancer-related m6A-SNPs	6
Epigenome-wide association study of long-term psychosocial stress in older adults	6
Correction	6
In vivo DNA methylation editing in zebrafish	6
Association of changes in expression of HDAC and SIRT genes after drug treatment with cancer cell line sensitivity to kinase inhibitors	6
Vitamin C enhances co-localization of novel TET1 nuclear bodies with both Cajal and PML bodies in colorectal cancer cells	6
Weight loss reduces circulating micro-RNA related to obesity and breast cancer in postmenopausal women	6
Homocysteine affects macrophage polarization by altering m6A methylation of scavenger receptors CD209 and CD163L1	6
Pruning and thresholding approach for methylation risk scores in multi-ancestry populations	6
Chimpanzee Extraversion scores vary with epigenetic modification of dopamine receptor gene D2 (DRD2) and early rearing conditions	6
Animal and plant protein intake during infancy and childhood DNA methylation: a meta-analysis in the NutriPROGRAM consortium	6
Epigenome-wide association study of global cortical volumes in generation Scotland: Scottish family health study	6
Epigenetic control of the imprinted growth regulator Cdkn1c in cadmium-induced placental dysfunction	6
A qualitative prognostic biomarker for melanoma based on the relative methylation orderings of CpG loci	5
Long-range chromosomal interactions increase and mark repressed gene expression during adipogenesis	5
ABCA1, TCF7, NFATC1, PRKCZ, and PDGFA DNA methylation as potential epigenetic-sensitive targets in acute coronary syndrome via network analysis	5
The chromatin remodelling protein LSH/HELLS regulates the amount and distribution of DNA hydroxymethylation in the genome	5
Transmission of reduced levels of miR-34/449 from sperm to preimplantation embryos is a key step in the transgenerational epigenetic inheritance of the effects of paternal chronic social instability s	5
CD4+T-cell DNA methylation changes during pregnancy significantly correlate with disease-associated methylation changes in autoimmune diseases	5
A promising application of kidney-specific cell-free DNA methylation markers in real-time monitoring sepsis-induced acute kidney injury	5
Evaluation of methylated DCR1 as a biomarker for response to adjuvant irinotecan-based therapy in stage III colon cancer: cancer and leukaemia Group B 89803 (Alliance)	5

Methylation patterns associated with C-reactive protein in racially and ethnically diverse populations	5
Circ-0006332 stimulates cardiomyocyte pyroptosis via the miR-143/TLR2 axis to promote doxorubicin-induced cardiac damage	5
Prenatal exposure to endocrine disrupting chemicals is associated with altered DNA methylation in cord blood	5
Non-pathogenic microbiota accelerate age-related CpG Island methylation in colonic mucosa	5
Aberrant regulation of CXCR4 in cancer via deviant microRNA-targeted interactions	5
Resistance and aerobic training increases genome-wide DNA methylation in women with polycystic ovary syndrome	5
Evaluating the utility of ZNF331 promoter methylation as a prognostic and predictive marker in stage III colon cancer: results from CALGB 89803 (Alliance)	5
Ribosomal DNA Copy Number Variation is Coupled with DNA Methylation Changes at the 45S rDNA Locus	5
Non-coding 886 ( nc886 / vtRNA2-1 ), the epigenetic odd duck – implications for future studies	5
Association of mammographic density with blood DNA methylation	5
Chromatin and transcriptomic profiling uncover dysregulation of the Tip60 HAT/HDAC2 epigenomic landscape in the neurodegenerative brain	4
Perinatal stress and methylation of the NR3C1 gene in newborns: systematic review	4
Associations of green and blue space exposure in pregnancy with epigenetic gestational age acceleration	4
Comparison between indicine and taurine cattle DNA methylation reveals epigenetic variation associated to differences in morphological adaptive traits	4
DNA methylation heterogeneity attributable to a complex tumor immune microenvironment prompts prognostic risk in glioma	4
Exploration of genome-wide DNA methylation profiles in night shift workers	4
DNA hypomethylation mediates immune response in pan-cancer	4
MIMOSA: a resource consisting of improved methylome prediction models increases power to identify DNA methylation-phenotype associations	4
DNA methylation and gene expression changes in mouse mammary tissue during successive lactations: part I – the impact of inflammation	4
The effect of experimental lead pollution on DNA methylation in a wild bird population	4
Epigenetic editing of BRCA1 promoter increases cisplatin and olaparib sensitivity of ovarian cancer cells	4
Multiple tissue-specific epigenetic alterations regulate persistent gene expression changes following developmental DES exposure in mouse reproductive tissues	4
A polyepigenetic glucocorticoid exposure score and HPA axis-related DNA methylation are associated with gestational epigenetic aging	4
Epigenome-wide scan identifies differentially methylated regions for lung cancer using pre-diagnostic peripheral blood	4
Early-pregnancy maternal body mass index is associated with common DNA methylation markers in cord blood and placenta: a paired-tissue epigenome-wide association study	4
Identification of novel susceptibility methylation loci for pancreatic cancer in a two-phase epigenome-wide association study	4
Sex-specific DNA methylation in saliva from the multi-ethnic Future of Families and Child Wellbeing Study	4
DNA methylation and gene expression changes in mouse mammary tissue during successive lactations: part II – the impact of lactation rank	4
Phenotypic and transcriptomic impact of expressing mammalian TET2 in theDrosophila melanogastermodel	4
Disease-related blood-based differential methylation in cystic fibrosis and its representation in lung cancer revealed a regulatory locus inPKP3in lung epithelial cells	4
FTO promotes proliferation and migration of bladder cancer via enhancing stability of STAT3 mRNA in an m6A-dependent manner	4
Epigenome-wide association study of systemic effects of obesity susceptibility in human twins	4
Astrocyte-derived exosomes regulate sperm miR-34c levels to mediate the transgenerational effects of paternal chronic social instability stress	4