Epigenetics

Article	Citations
Co-occurrence of injection drug use and hepatitis C increases epigenetic age acceleration that contributes to all-cause mortality among people living with HIV	93
Transcriptional signature of cardiac myocyte recovery in mice and human reveals persistent upregulation of epigenetic factors	67
N6-methyladenosine methylation analysis of long noncoding RNAs and mRNAs in 5-FU-resistant colon cancer cells	41
Leukocyte DNA methylation in Alzheimer´s disease associated genes: replication of findings from neuronal cells	39
Identification and functional characterisation of DNA methylation differences between East- and West-originating Finns	35
Role of N6-methyladenosine-related lncRnas in pseudoexfoliation glaucoma	30
Early characterization of pregnancy glycemic traits in gestational diabetes mellitus by plasma cell-free mRNA and non-coding RNA	29
Epigenetic landscape of 5-hydroxymethylcytosine and associations with gene expression in placenta	27
Using methylation data to improve transcription factor binding prediction	27
Development and validation of a digital PCR assay targeting plasma FAR1 methylation for early detection of hepatocellular carcinoma	26
Differential methylation patterns in cord blood associated with prenatal exposure to neighborhood crime: an epigenome-wide association study and regional analysis	25
Placental DNA methylation in pregnancies complicated by maternal diabetes and/or obesity: State of the art and research gaps	25
Digital methylation assessments of alcohol and cigarette consumption account for common variance in accelerated epigenetic ageing	25
Differential methylation pattern in pubertal girls associated with biochemical premature adrenarche	23
GGNBP2 regulates histone ubiquitination and methylation in spermatogenesis	23
Immune pathways and prenatal/perinatal environmental exposures contribute to epigenetic gestational age prediction and acceleration	22
The influence of intergenerational trauma on epigenetics and obesity in Indigenous populations - a scoping review	22
Multiomics analysis of adaptation to repeated DNA damage in prostate cancer cells	22
Integrative DNA methylation and transcriptome analysis reveal cell-type specific patterns in response to elevated allostatic load	21
Detailed immune profiling in pediatric Crohn’s disease using methylation cytometry	21
Proposal of a bioinformatics approach to predict molecular mechanisms involved in inflammatory response: case of ATRA and 1,25(OH) 2 D in adipocytes	20
A novel lncRNA, Lnc21q22.11, suppresses gastric cancer growth by inhibiting MEK/ERK pathway	19
Mechanism of crosstalk between DNA methylation and histone acetylation and related advances in diagnosis and treatment of premature ovarian failure	19
CircRNF111 Contributes to Adipocyte Differentiation by Elevating PPARγ Expression via miR-27a-3p	19
Chromatin structural gene expression stratifies cardiac cell populations in health and disease	19

Placental malaria induces a unique methylation profile associated with fetal growth restriction	19
Generational stability of epigenetic transgenerational inheritance facilitates adaptation and evolution	19
ACMSD methylation in peripheral blood is associated with dynamic functional connectivity pattern in adolescent MDD patients	18
Identification and characterization of extrachromosomal circular DNA in patients with high myopia and cataract	18
The UHRF1 protein is a key regulator of retrotransposable elements and innate immune response to viral RNA in human cells	18
Identification cloning and functional analysis of novel natural antisense lncRNA CFL1-AS1 in cattle	18
Epigenome-wide association study of loneliness in a sample of U.S. middle-aged twins	17
Acetaldehyde-driven mRNA methylation and expression changes in ethanol-metabolizing enzyme genes	17
Accelerated epigenetic age at birth and child emotional and behavioural development in early childhood: a meta-analysis of four prospective cohort studies in ECHO	17
MYCN and HIF-1 directly regulate TET1 expression to control 5-hmC gains and enhance neuroblastoma cell migration in hypoxia	17
Placental and immune cell DNA methylation reference panel for bulk tissue cell composition estimation in epidemiological studies	17
Genomic context determines the effect of DNA methylation on gene expression in the gut epithelium of Atlantic salmon ( Salmo salar )	17
Mendelian randomization analysis of CpG methylation and immune phenotypes in epithelial ovarian cancer outcomes	17
PIK3R1 and G0S2 are human placenta-specific imprinted genes associated with germline-inherited maternal DNA methylation	16
Pan-precancer and cancer DNA methylation profiles revealed significant tissue specificity of interrupted biological processes in tumorigenesis	16
ELOVL2-AS1 suppresses tamoxifen resistance by sponging miR-1233-3p in breast cancer	16
Direction-aware functional class scoring enrichment analysis of infinium DNA methylation data	16
Evaluating ancestry adjustment in multi-ancestry epigenome-wide analysis	16
Polymethylation scores for prenatal maternal smoke exposure persist until age 15 and are detected in saliva in the Fragile Families and Child Wellbeing cohort	16
Regulatory networks of circRNA- centred ceRNAs in sepsis-induced acute kidney injury	16
Changes in nuclear and mitochondrial DNA methylation in cow blood associated with age and disease	15
Integration of miRNA expression analysis of purified leukocytes and whole blood reveals blood-borne candidate biomarkers for lung cancer	15
CpG island demethylation and recruitment of SP1 to the promoter region regulates human thymic stromal lymphopoietin expression	15
Upregulation of KHDC1L promotes the proliferation and inhibits apoptosis in head and neck squamous cell carcinoma	15
The role of histone methyltransferases in therapeutic resistance of NSCLC	15
Large-scale integration of DNA methylation and gene expression array platforms identifies both cis and trans relationships	15
Timing of dietary effects on the epigenome and their potential protective effects against toxins	15
Tributyltin chloride alters the structural, genomic, and epigenomic integrity of postejaculatory mammalian sperm	15
Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome	15
The role of DNA methylation on gene expression in the vertebrae of ancestrally benzo[a]pyrene exposed F1 and F3 male medaka	15
The one-carbon metabolism as an underlying pathway for placental DNA methylation – a systematic review	15
Chemotherapy-induced acceleration of DNA methylation-based biological age in breast cancer	15
Comprehensive analysis of m 6 A methylomes in idiopathic pulmonary arterial hypertension	15
Long non-coding RNA Gm10561 promotes myogenesis by sponging miR-432	14
Cut&tag: a powerful epigenetic tool for chromatin profiling	14
DNA-based cell typing in menstrual effluent identifies cell type variation by sample collection method: toward noninvasive biomarker development for women’s health	14
Cumulative stress, PTSD, and emotion dysregulation during pregnancy and epigenetic age acceleration in Hispanic mothers and their newborn infants	14
DNMT1 expression partially dictates 5-Azacytidine sensitivity and correlates with RAS/MEK/ERK activity in gastric cancer cells	13
Heavy alcohol consumption but not smoking predicts mortality in patients with acute coronary syndrome	13
Dietary and supplemental intake of vitamins C and E is associated with altered DNA methylation in an epigenome-wide association study meta-analysis	13
ΔNp63α-mediated epigenetic regulation in keratinocyte senescence	13
Gaps in current methods to detect polymorphic CpGs from Illumina Infinium human methylation microarrays and exploring their potential impact in multi-EWAS analyses	13
DNA methylation at birth and fine motor ability in childhood: an epigenome-wide association study with replication	13
Research progress on the mechanism of tumor cell ferroptosis regulation by epigenetics	13
Study on chromatin regulation patterns of expression vectors in the PhiC31 integration site	13
Hypomethylation at H19DMR in penile squamous cell carcinoma is not related to HPV infection	13
Detecting aberrant DNA methylation in Illumina DNA methylation arrays: a toolbox and recommendations for its use	12
Biological stability of DNA methylation measurements over varying intervals of time and in the presence of acute stress	12
NSUN2-mediated RNA m5C modification modulates uveal melanoma cell proliferation and migration	12
Associations of breast DNA methylation–based measures of biological ageing with obesity-related breast cancer risk markers	12

Assessment of aberrant DNA methylation two years after paediatric critical illness: a pre-planned secondary analysis of the international PEPaNIC trial	12
Analysis of global DNA methylation and epigenetic modifiers (DNMTs and HDACs) in human foetal endothelium exposed to gestational and type 2 diabetes	12
DNA methylation profiles in bovine sperm are associated with daughter fertility	12
Comparative genomic analyses reveal evidence for adaptive A-to-I RNA editing in insect Adar gene	12
mir152hypomethylation as a mechanism for non-syndromic cleft lip and palate	12
Upregulation of GPR133 expression impaired the phagocytosis of macrophages in recurrent spontaneous miscarriage	12
RNA modification m 6 Am: the role in cardiac biology	12
Epigenetic age acceleration, neonatal morbidities, and neurobehavioral profiles in infants born very preterm	12
Epigenome wide association study in peripheral blood of pregnant women identifies potential metabolic pathways related to gestational diabetes	12
Prenatal Socioeconomic Disadvantage and Epigenetic Alterations at Birth Among Children Born to White British and Pakistani Mothers in the Born in Bradford Study	11
Oleic acid-related anti-inflammatory effects in force-stressed PdL fibroblasts are mediated by H3 lysine acetylation associated with altered IL10 express	11
Genome-wide DNA methylation profiles and ribosomal DNA copy number at birth	11
Higher sperm H3K4me3 levels are associated with idiopathic recurrent pregnancy loss	11
A novel principal component based method for identifying differentially methylated regions in Illumina Infinium MethylationEPIC BeadChip data	11
Transient elevation in cellular glucose uptake exacerbates pressure overload-induced cardiac hypertrophy and dysfunction	11
Emerging roles of RNA N5-methylcytosine modification in reproductive physiology and gynecological diseases	11
DNA methylation and bronchiectasis: a Mendelian randomization analysis to investigate causal link and therapeutic target	11
Domain architecture and protein–protein interactions regulate KDM5A recruitment to the chromatin	11
Insight into the mechanisms and dysregulation of KMT5C-H4K20me3 in cancer	11
Detection of DNA methylation from buccal swabs using nanopore sequencing to study stunting	11
Uncertainty quantification of reference-based cellular deconvolution algorithms	11
m6A reader YTHDC2 mediates NCOA4 mRNA stability affecting ferritinophagy to alleviate secondary injury after intracerebral haemorrhage	11
Decitabine-induced DNA methylation remodeling reveals targetable biological processes in gilthead seabream pituitary and liver explants	11
Methylome profile of medaka eggs and sperm	11
Advancements in DNA methylation technologies and their application in cancer diagnosis	10
Time-course full profiling of circulating miRNAs in neurologically deceased organ donors: a proof of concept study to understand the onset of the cytokine storm	10
History of exposure to copper influences transgenerational gene expression responses in Daphnia magna	10
Comprehensive analysis of transcriptome‐wide M 6 A methylation for hepatic ischaemia reperfusion injury in mice	10
Precise epigenomic editing with a SunTag-based modular epigenetic toolkit	10
Circ_0003747 promotes thyroid cancer progression by sponging miR-338-3p to upregulate PLCD3 expression	10
Catalytic domain-dependent and -independent transcriptional activities of the tumour suppressor histone H3K27 demethylase UTX/KDM6A in specific cancer types	10
The multifaceted role of lactate in cardiovascular health: from metabolism to signaling and epigenetics	10
DNA methylation biomarkers to identify epigenetically abnormal spermatozoa in male partners from couples experiencing recurrent pregnancy loss	10
Stress-induced epigenetic effects driven by maternal lactation in dairy cattle: a comethylation network approach	10
Epigenome-wide meta-analysis of prenatal vitamin D insufficiency and cord blood DNA methylation	10
Sex-based differences in placental DNA methylation profiles related to gestational age: an NIH ECHO meta-analysis	9
Plasma methylated GNB4 and Riplet as a novel dual-marker panel for the detection of hepatocellular carcinoma	9
Dose rate dependent reduction in chromatin accessibility at transcriptional start sites long time after exposure to gamma radiation	9
Silencing of optogenetic and chemogenetic transgenes in human iPSCs involves promoter methylation and methylation-independent mechanisms	9
Identification of blood-derived DNA methylation biomarkers of glaucoma and intraocular pressure measurements in three European ancestry cohorts including the Canadian longitudinal study on aging	9
Parental arsenic exposure and tissue-specific DNA methylation in Bangladeshi infants with spina bifida	9
Decoding epigenetic markers: implications of traits and genes through DNA methylation in resilience and susceptibility to mastitis in dairy cows	9
Implementation of the Methyl-Seq platform to identify tissue- and sex-specific DNA methylation differences in the rat epigenome	9
Genome-wide methylation analysis in patients with proximal hypospadias – a pilot study and review of the literature	9
Glucocorticoid receptor epigenetic activity in the heart	9
Comparative and integrative analysis of transcriptomic and epigenomic-wide DNA methylation changes in African American prostate cancer	9
Maternal adverse childhood experiences (ACEs) and offspring imprinted gene DMR methylation at birth	9
Sex and tissue-specificity of piRNA regulation in adult mice following perinatal lead (Pb) exposure	9
Spontaneous and ART-induced large offspring syndrome: similarities and differences in DNA methylome	8
Fumonisin B 1 induces global DNA hypermethylation in human glioblastoma U87MG cells	8
Letter to the editor: critical evaluation of the reliability of DNA methylation probes on the illumina MethylationEPIC v1.0 BeadChip microarrays	8
Association of changes in expression of HDAC and SIRT genes after drug treatment with cancer cell line sensitivity to kinase inhibitors	8
Identification of differentially methylated genes for severe acne by genome-wide DNA methylation and gene expression analysis	8
MK-801-exposure induces increased translation efficiency and mRNA hyperacetylation of Grin2a in the mouse prefrontal cortex	8
Combined exercise training decreases blood pressure in OLDER women with NOS3 polymorphism providing changes in differentially methylated regions (DMRs)	8
Imprinted gene alterations in the kidneys of growth restricted offspring may be mediated by a long non-coding RNA	8
A cell type enrichment analysis tool for brain DNA methylation data (CEAM)	8
IL21R hypomethylation as a biomarker for distinguishing benign and malignant breast tumours	8
In silico identification and in vitro expression analysis of breast cancer-related m6A-SNPs	8
Genome wide exploration of the methylome in aggressive B-cell lymphoma in Golden Retrievers reveals a conserved hypermethylome	8
Epigenome-wide association study of long-term psychosocial stress in older adults	7
Long-range chromosomal interactions increase and mark repressed gene expression during adipogenesis	7
Epigenetic ageing of the prefrontal cortex and cerebellum in humans and chimpanzees	7
Homocysteine affects macrophage polarization by altering m6A methylation of scavenger receptors CD209 and CD163L1	7
In vivo DNA methylation editing in zebrafish	7
Correction	7
Animal and plant protein intake during infancy and childhood DNA methylation: a meta-analysis in the NutriPROGRAM consortium	7
YY1/circCTNNB1/miR-186-5p/YY1 positive loop aggravates lung cancer progression through the Wnt pathway	7
Epigenetic control of the imprinted growth regulator Cdkn1c in cadmium-induced placental dysfunction	7
Vitamin C enhances co-localization of novel TET1 nuclear bodies with both Cajal and PML bodies in colorectal cancer cells	7
Evaluating the utility of ZNF331 promoter methylation as a prognostic and predictive marker in stage III colon cancer: results from CALGB 89803 (Alliance)	7
Chromatin accessibility profiling of Treg cells in acute urticaria	7
Aberrant regulation of CXCR4 in cancer via deviant microRNA-targeted interactions	6
Resistance and aerobic training increases genome-wide DNA methylation in women with polycystic ovary syndrome	6
Non-coding 886 ( nc886 / vtRNA2-1 ), the epigenetic odd duck – implications for future studies	6
Transmission of reduced levels of miR-34/449 from sperm to preimplantation embryos is a key step in the transgenerational epigenetic inheritance of the effects of paternal chronic social instability s	6
Methylation patterns associated with C-reactive protein in racially and ethnically diverse populations	6
A qualitative prognostic biomarker for melanoma based on the relative methylation orderings of CpG loci	6
A promising application of kidney-specific cell-free DNA methylation markers in real-time monitoring sepsis-induced acute kidney injury	6
Pruning and thresholding approach for methylation risk scores in multi-ancestry populations	6

Circ-0006332 stimulates cardiomyocyte pyroptosis via the miR-143/TLR2 axis to promote doxorubicin-induced cardiac damage	6
Phenotypic and transcriptomic impact of expressing mammalian TET2 in theDrosophila melanogastermodel	6
Targeted epigenetic silencing of UCHL1 expression suppresses collagen-1 production in human lung epithelial cells	6
m 6 A RNA methylation regulators predict prognosis and indicate characteristics of tumour microenvironment infiltration in acute myeloid leukaemia	6
Weight loss reduces circulating micro-RNA related to obesity and breast cancer in postmenopausal women	6
Ribosomal DNA Copy Number Variation is Coupled with DNA Methylation Changes at the 45S rDNA Locus	6
Associations of green and blue space exposure in pregnancy with epigenetic gestational age acceleration	6
MIMOSA: a resource consisting of improved methylome prediction models increases power to identify DNA methylation-phenotype associations	5
Epigenetic editing of BRCA1 promoter increases cisplatin and olaparib sensitivity of ovarian cancer cells	5
Sex-specific DNA methylation in saliva from the multi-ethnic Future of Families and Child Wellbeing Study	5
Differential DNA methylation clock ages across buffy coat (BC), peripheral blood mononuclear cells (PBMC), and saliva in individuals in early-to-mid adulthood	5
SOX6 AU controls myogenesis by cis-modulation of SOX6 in cattle	5
Genome-wide methylation profile of mitochondrial DNA across bovine preimplantation development	5
Epigenome-wide association study of systemic effects of obesity susceptibility in human twins	5
Strength of evidence for paternal influence on offspring epigenome in observational human studies: a systematic review and risk-of-bias appraisal for non-randomized exposures	5
Dominant effects of the histone mutant H3-L61R on Spt16-gene interactions in budding yeast	5
Exploration of genome-wide DNA methylation profiles in night shift workers	5
Multiple tissue-specific epigenetic alterations regulate persistent gene expression changes following developmental DES exposure in mouse reproductive tissues	5
Non-pathogenic microbiota accelerate age-related CpG Island methylation in colonic mucosa	5
Comparison between indicine and taurine cattle DNA methylation reveals epigenetic variation associated to differences in morphological adaptive traits	5
DNA methylation heterogeneity attributable to a complex tumor immune microenvironment prompts prognostic risk in glioma	5
LncRNA NEAT1 aggravates human microvascular endothelial cell injury by inhibiting the Apelin/Nrf2/HO-1 signalling pathway in type 2 diabetes mellitus with obstructive sleep apnoea	5
Expression profiles of histone H4K20 methylation and its associated enzymes in mouse cardiac disease and human heart failure	5
DNA methylation and gene expression changes in mouse mammary tissue during successive lactations: part I – the impact of inflammation	5
Clinical significance of peripheral blood DDR1 and CtBP gene methylation detection in patients with acute pancreatitis	5
DNA methylation and gene expression changes in mouse mammary tissue during successive lactations: part II – the impact of lactation rank	5
LncRNA SCARNA8 promotes atherosclerotic plaque instability by inhibiting macrophage efferocytosis	5
Astrocyte-derived exosomes regulate sperm miR-34c levels to mediate the transgenerational effects of paternal chronic social instability stress	5
FTO promotes proliferation and migration of bladder cancer via enhancing stability of STAT3 mRNA in an m6A-dependent manner	5
The role of R-loops-mediated epigenetic regulation in genome stability maintenance and disease pathogenesis: a systematic review	5
Oncogenic DNA methyltransferase 1 activates the PI3K/AKT/mTOR signalling by blocking the binding of HSPB8 and BAG3 in melanoma	5
A polyepigenetic glucocorticoid exposure score and HPA axis-related DNA methylation are associated with gestational epigenetic aging	5
DNA hypomethylation mediates immune response in pan-cancer	5