OOIR: Observatory of International Research

Papers

(The TQCC of Clinical Toxicology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
2019 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 37th Annual Report	261
2020 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 38th Annual Report	215
2021 Annual Report of the National Poison Data System ^© (NPDS) from America’s Poison Centers: 39th Annual Report	109
North American Congress of Clinical Toxicology (NACCT) 2022	92
North American Congress of Clinical Toxicology (NACCT) 2023	84
43rd International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT), 23–26 May 2023, Palma de Mallorca, Spain	60
2022 Annual Report of the National Poison Data System ^® (NPDS) from America’s Poison Centers ^® : 40th Annual Report	39
Opioid overdoses involving xylazine in emergency department patients: a multicenter study	36
42nd International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT) 24-27 May 2022, Tallinn, Estonia	34
Reddit discussions about buprenorphine associated precipitated withdrawal in the era of fentanyl	34
Xylazine poisoning: a systematic review	32
Pediatric cannabis intoxication trends in the pre and post-legalization era	32
The serotonin toxidrome: shortfalls of current diagnostic criteria for related syndromes	30
Nine prohibited stimulants found in sports and weight loss supplements: deterenol, phenpromethamine (Vonedrine), oxilofrine, octodrine, beta-methylphenylethylamine (BMPEA), 1,3-dimethylamylamine (1,3-	28
Rising incidence and high mortality in intentional sodium nitrite exposures reported to US poison centers	27
Acute diquat poisoning resulting in toxic encephalopathy: a report of three cases	26
Poisoning during the COVID-19 outbreak and lockdown: retrospective analysis of exposures reported to French poison control centres	25
Fatal serotonin syndrome: a systematic review of 56 cases in the literature	25
Ivermectin: a mini-review	25
Sodium azide poisoning: a narrative review	25
A randomized trial comparing physostigmine vs lorazepam for treatment of antimuscarinic (anticholinergic) toxidrome	24
41st International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT) 25-28 May 2021, Virtual Meeting	24
Extracorporeal membrane oxygenation use in poisoning: a narrative review with clinical recommendations	23
Fomepizole as an adjunct in acetylcysteine treated acetaminophen overdose patients: a case series	22
Amanitin intoxication: effects of therapies on clinical outcomes – a review of 40 years of reported cases	22

Extracorporeal treatment for calcium channel blocker poisoning: systematic review and recommendations from the EXTRIP workgroup	21
Systematic review on the use of activated charcoal for gastrointestinal decontamination following acute oral overdose	21
The early impact of paraquat ban on suicide in Taiwan	18
Snakebite-associated thrombotic microangiopathy: an Australian prospective cohort study [ASP30]	17
Blood concentrations of synthetic cathinones	17
Variation of drugs involved in acute drug toxicity presentations based on age and sex: an epidemiological approach based on European emergency departments	17
Dose-response relationships in aluminium toxicity in humans	17
Methadone and suboxone^® mentions on twitter: thematic and sentiment analysis	16
Nitrous oxide abuse induced subacute combined degeneration despite patient initiated B12 supplementation	16
Wastewater analysis for psychoactive substances at music festivals across New South Wales, Australia in 2019–2020	16
Methamphetamine exposures reported to United States poison control centers, 2000–2019	15
Respiratory failure in confirmed synthetic cannabinoid overdose	15
Evaluation of N-acetylcysteine dose for the treatment of massive acetaminophen ingestion	15
Intentional pesticide poisoning and pesticide suicides in Nepal	14
Does vitamin B12 deficiency explain psychiatric symptoms in recreational nitrous oxide users? A narrative review	14
Death associated with brorphine, an emerging novel synthetic opioid	13
Identification of a novel opioid, N-piperidinyl etonitazene (etonitazepipne), in patients with suspected opioid overdose	13
Letter in response to Rivastigmine for the treatment of anticholinergic delirium following severe procyclidine intoxication	12
Changes in California cannabis exposures following recreational legalization and the COVID-19 pandemic	12
Sentanyl: a comparison of blood fentanyl concentrations and naloxone dosing after non-fatal overdose	12
The clinical toxicology of ketamine	12
New psychoactive substance cocktail in an intensive care intoxication case elucidated by molecular networking	12
Increased rates of diphenhydramine overdose, abuse, and misuse in the United States, 2005–2016	12
Death by hand sanitizer: syndemic methanol poisoning in the age of COVID-19	11
Vasodilation in patients with calcium channel blocker poisoning treated with high-dose insulin: a comparison of amlodipine versus non-dihydropyridines	11
Bowel obstruction following ingestion of superabsorbent polymers beads: literature review	11
Bites by the noble false widow spider Steatoda nobilis can induce Latrodectus-like symptoms and vector-borne bacterial infections with implications for public health: a case series	11
Treating ethylene glycol poisoning with alcohol dehydrogenase inhibition, but without extracorporeal treatments: a systematic review	11
Moderate-to-severe Vipera berus envenoming requiring ViperaTAb antivenom therapy in the UK	11
Emergency department visits due to new psychoactive substances and other illicit drugs in Taiwan: preliminary results of the Taiwan Emergency Department Drug Abuse Surveillance (TEDAS) project	11
Alterations in cerebral and cardiac mitochondrial function in a porcine model of acute carbon monoxide poisoning	10
Lipid emulsion for the treatment of acute organophosphate poisoning: an Open-Label randomized trial	10
Clinical symptoms and blood concentration of new psychoactive substances (NPS) in intoxicated and hospitalized patients in the Budapest region of Hungary (2018-19)	10
Pesticide use, agricultural outputs, and pesticide poisoning deaths in Japan	10
Clinical outcome of massive acetaminophen overdose treated with standard-dose N-acetylcysteine	10
Synthetic cannabis: adverse events reported to the New Zealand Pharmacovigilance Centre	10
Ivermectin associated adverse events in the treatment and prevention of COVID-19 reported to the FACT pharmacovigilance project	10
Clinical experience with titrating doses of digoxin antibodies in acute digoxin poisoning. (ATOM-6)	10
Australian snakebite myotoxicity (ASP-23)	9
Distinguishing between toxic alcohol ingestion vs alcoholic ketoacidosis: how can we tell the difference?	9
Bites by exotic snakes reported to the UK National Poisons Information Service 2009–2020	9
Novel psychoactive substances-related presentations to the emergency departments of the European drug emergencies network plus (Euro-DEN plus) over the six-year period 2014–2019	9
Retained bullets and lead toxicity: a systematic review	9
An examination of fatal child poisonings in the United States using the National Violent Death Reporting System (NVDRS), 2012–2017	9
A cluster of tetrodotoxin poisoning in Oman	9
Clinical and pathophysiological characteristics of valproate-induced pleural effusion	9
Transdermal buprenorphine for in-hospital transition from full agonist opioids to sublingual buprenorphine: a retrospective observational cohort study	9
Diquat poisoning in a pregnant woman resulting in a miscarriage and maternal death	9
Analytically confirmed eutylone (bk-EBDB) exposure in emergency department patients	8
Trends in intentional abuse and misuse ingestions in school-aged children and adolescents reported to US poison centers from 2000-2020	8

Clinical and patient characteristics associated with severe outcome in diphenhydramine toxicity	8
Pediatric suicides reported to U.S. poison centers	8
Trends of prescription psychotropic medication exposures in pediatric patients, 2009–2018	8
Efficacy of lipid emulsion therapy in treating cardiotoxicity from diphenhydramine ingestion: a review and analysis of case reports	8
Does the ICU Requirement Score allow the poisoned patient to be safely managed without admission to the intensive care unit? – a validation cohort study	8
The role of a point-of-care ultrasound protocol in facilitating clinical decisions for snakebite envenomation in Taiwan: a pilot study	8
Quantity of phenibut in dietary supplements before and after FDA warnings	8
Characteristics of ivermectin toxicity in patients taking veterinary and human formulations for the prevention and treatment of COVID-19	8
Differences in clinical features associated with cannabis intoxication in presentations to European emergency departments according to patient age and sex	8
Critical care interventions in children aged 6 months to 12 years admitted to the pediatric intensive care unit after unintentional cannabis exposures	8
Safety and effectiveness concerns of lopinavir/ritonavir in COVID-19 affected patients: a retrospective series	8
Evaluating the impact of home quarantine during the coronavirus pandemic on pediatric exploratory ingestions	7
Poisoning in older adults: characterization of exposures reported to the Dutch Poisons Information Center	7
Synthetic cannabinoid poisonings and access to the legal cannabis market: findings from US national poison centre data 2016–2019	7
Descriptive epidemiology of clinically significant occupational poisonings, United States, 2008–2018	7
A cluster of lysergic acid diethylamide (LSD) poisonings following insufflation of a white powder sold as cocaine	7
Clinical and pathological characteristics of acute kidney injury caused by diquat poisoning	7
Factors associated with seizure development after bupropion overdose: a review of the toxicology investigators consortium	7
Severe intentional sodium nitrite poisoning is also being seen in France	7
Effect of the first wave of COVID-19 on Poison Control Centre activities in 21 European countries: an EAPCCT initiative	7
Fomepizole as an adjunctive therapy for acetaminophen poisoning: cases reported to the toxicology investigators consortium (ToxIC) database 2015–2020	7
Impact of marijuana legalization on cannabis-related visits to the emergency department	7
Severe Heloderma spp. envenomation: a review of the literature	7
Suspected Fanconi syndrome from cadmium toxicity exacerbated by heavy kratom use. A rare occurrence	7
Clinical features associated with ADB-BUTINACA exposure in patients attending emergency departments in England	6
Predicting serotonin toxicity in serotonin reuptake inhibitor overdose	6
Single bag high dose intravenous N-acetylcysteine associated with decreased hepatotoxicity compared to triple bag intravenous N-acetylcysteine in high-risk acetaminophen ingestions	6
Genetic variants associated with ALT elevation from therapeutic acetaminophen	6
Hyperammonemia in acetaminophen toxicity	6
Silibinin: a toxicologist’s herbal medicine?	6
Performance of the paracetamol-aminotransferase multiplication product in risk stratification after paracetamol (acetaminophen) poisoning: a systematic review and meta-analysis	6
Acute toxicity from the synthetic cathinone N-ethylpentylone (ephylone) in the United Kingdom	6
International trends in systemic human exposures to 2,4 dinitrophenol reported to poisons centres	6
Changes in unintentional cannabis exposures in children 6 months to 5 years reported to United States poison centers during the first nine months of the coronavirus-19 pandemic	6
A cluster of 25B-NBOH poisonings following exposure to powder sold as lysergic acid diethylamide (LSD)	6
Detection of flubromazolam in patients with suspected non-medical drug use attending emergency departments in the United Kingdom	6
Hospital encounters for pediatric ingestions before and during the COVID-19 pandemic	6
Poison center consultation reduces hospital length of stay	6
Suspected suicides and suicide attempts involving antipsychotic or sedative-hypnotic medications reported to America’s Poison Centers, 2000–2021	6
Relative safety and quality of various dietary supplement products U.S. Service Members ask about	6
Is secondary chemical exposure of hospital personnel of clinical importance?	6
The unapproved drug centrophenoxine (meclofenoxate) in cognitive enhancement dietary supplements	6
Lead poisoning due to incense burning: an outbreak in a family	6
Internet-assisted suicide by nitrite poisoning – a case report and increase in reported intentional nitrite/nitrate exposures in U.S. Poison Center data	6
Opioid exposure associated with poppy consumption reported to poison control centers and the U.S. Food and Drug Administration	6
N-desethyl isotonitazene detected in polydrug users admitted to hospital in Birmingham, United Kingdom	6
Thiocyanate toxicity: a teaching case	6
Coagulopathy after snake envenomation in South Korea	6
Increase in pregabalin recreational use in adolescents in France	6
The clinical course and treatment of black mamba (Dendroaspis polylepis) envenomations: a narrative review	6
Comparison of clinical characteristics between meth/amphetamine and synthetic cathinone users presented to the emergency department	6
Suspected suicides and nonfatal suicide attempts involving antidepressants reported to United States poison control centers, 2000–2020	6
Epidemiology of scorpionism in France: nationwide scorpion exposure	6
Characteristics of fatal gabapentinoid-related poisoning in Australia, 2000–2020	6
Dose-related hypoglycemia in venlafaxine poisoning: a retrospective cohort study	5
Disposition of toxic drugs and chemicals in man	5
Clinical effects and factors associated with adverse clinical outcomes of hymenopteran stings treated in a Thai Poison Centre: a retrospective cross-sectional study	5
Unintentional buprenorphine and methadone poisoning in children: a matched observational study	5
Accuracy of substance exposure history in patients attending emergency departments after substance misuse; a comparison with biological sample analysis	5
Epidemiology of poisoning in Syria (1999 through 2020)	5
Clinical presentation of type 1 and type 2 pyrethroid poisoning in humans	5
Neurotoxic effects of nephrotoxic compound diethylene glycol	5
A two-bag acetylcysteine regimen is associated with shorter delays and interruptions in the treatment of paracetamol overdose	5
Cannabidiol exposures in the United States, National Poison Data System, July 2014–June 2021	5
Cocaine exposures reported to United States poison control centers, 2000–2020	5
Involuntary MDMB-4en-PINACA intoxications following cannabis consumption: clinical and analytical findings	5
Dexamethasone therapy prevents delayed neuropsychiatric sequelae after carbon monoxide poisoning: a prospective registry-based study	5
Management of caustic ingestion: the time has come for consensus guidelines	5
Metformin-associated lactic acidosis reported to the United Kingdom National Poisons Information Service (NPIS) between 2010 and 2019: a ten-year retrospective analysis	5
Continuation of outpatient buprenorphine therapy after dispensing Buprenorphine-Naloxone from the emergency department	5
Effect of plasma exchange on colchicine elimination in overdose – a case report	5
Manganese concentration in patients with encephalopathy following ephedrone use: a narrative review and analysis of case reports	5
Rates and types of urine drug screen false negative results compared with confirmatory toxicology testing in major trauma patients	5
CAR-T and checkpoint inhibitors: toxicities and antidotes in the emergency department	5
Intentional avermectin pesticide ingestion: a retrospective multicenter study	5
Metabolomic markers predictive of hepatic adaptation to therapeutic dosing of acetaminophen	5
Early recovery of botulism: one decade of experience	5
Severe toxicity involving N-pyrrolidino etonitazene in the United Kingdom—a case report	5
Impaired neuromuscular function by conjoint actions of organophosphorus insecticide metabolites omethoate and cyclohexanol with implications for treatment of respiratory failure	5
Oral potassium overdose: a case series	4

Closing the xylazine knowledge gap	4
Qualitative and quantitative characteristics of xylazine-associated deaths detected using a post-mortem toxicology testing program	4
Delayed cardiotoxicity in venlafaxine and quetiapine overdose	4
Role of age-sex as underlying risk factors for death in acute pesticide self-poisoning: a prospective cohort study	4
Effectiveness of multiple-dose activated charcoal in lamotrigine poisoning: a case series	4
Validation of a nomogram used to predict lithium concentration in overdose	4
The acute paraquat poisoning mortality (APPM) score to predict the risk of death in paraquat-poisoned patients	4
Methyl mercaptan gas: mechanisms of toxicity and demonstration of the effectiveness of cobinamide as an antidote in mice and rabbits	4
Haff disease associated with consumption of buffalofish (Ictiobusspp.) in the United States, 2010–2020, with confirmation of the causative species	4
A case of fatal paralytic shellfish poisoning in Alaska	4
Population pharmacokinetics of Pseudechis porphyriacus (red-bellied black snake) venom in snakebite patients	4
A cluster of acute thebaine poisonings from non-food grade poppy seeds in the Australian food supply	4
E-cigarette or vaping-associated lung injury (EVALI): a review of international case reports from outside the United States of America	4
American College of Medical Toxicology and the American Academy of Clinical Toxicology position statement: nalmefene should not replace naloxone as the primary opioid antidote at this time	4
Major component causing neurological toxicity in acute glufosinate ammonium poisoning: determination of glufosinate, 1-methoxy-2-propanol, and ammonia in serum and cerebrospinal fluid	4
Independent validation of the Tanta University Risk Model for intensive care requirement in acutely poisoned adults	4
Population pharmacokinetic analysis of acetaminophen overdose with immediate release, extended release and modified release formulations	4
Continuous extracorporeal clearance in metformin-associated lactic acidosis and metformin-induced lactic acidosis: a systematic review	4
Are antimuscarinic effects common in hydroxyzine overdose? A cohort analysis of antimuscarinic effects in hydroxyzine and diphenhydramine-poisoned patients	4
Beverage ethanol exposures among infants reported to United States poison control centers	4
Predictors of FabAV use in copperhead envenomation	4
Successful treatment of potentially lethal dose thallium sulfate poisoning with sequential use of Prussian blue and multiple-dose activated charcoal	4
A systematic review of second line therapies in toxic seizures	4
Lipid emulsion facilitates reversal from volatile anesthetics in a rodent model	4
Evaluation of the relationship of xylazine and fentanyl blood concentrations among fentanyl-associated fatalities	4
Development of sodium tetrathionate as a cyanide and methanethiol antidote	4
Acquired methemoglobinemia in children presenting to Italian pediatric emergency departments: a multicenter report	4
Intravenous rifampicin use in the management of amanita phalloides toxicity	4
Mercury-associated neural epidermal growth factor-like 1 protein (NELL-1) positive membranous nephropathy after use of skin lightening creams	4
Human poisonings by neurotoxic phycotoxins related to the consumption of shellfish: study of cases registered by the French Poison Control Centres from 2012 to 2019	4
Accidental poisoning with autumn crocus ( Colchicum autumnale ): a case series	4
Massive tramadol ingestion resulting in fatal brain injury – a pharmacokinetic study with discussion on the involved mechanisms of toxicity	4
Birth outcomes in women exposed to diagnostic radiology procedures during first trimester of pregnancy: a prospective cohort study	4
Lipid emulsion therapy during management of the critically-ill poisoned patient: a prospective cohort study	4
Acute coronary syndrome from scombroid poisoning: a narrative review of case reports	4
Relationship between acute kidney injury and mortality in poisoning – a systematic review and metanalysis	4
Sodium bicarbonate treatment for QRS widening in bupropion overdoses	4