OOIR: Observatory of International Research

Papers

(The H4-Index of ACS Chemical Biology is 35. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Simple Enzymatic Incorporation of 2′OMeU Nucleotide at the End of the Poly-A Tail for Enhancement of the mRNA Stability and Protein Expression	236
Introducing Our Authors	108
Introducing Our Authors	105
Molecular Targeted Engagement of DPP9 in Rat Tissue Using CETSA, SP3 Processing, and Absolute Quantitation Mass Spectrometry	98
Visualization of Ectopic Serine Protease Activity by Förster Resonance Energy Transfer-Based Reporters	84
Antimicrobial Lasso Peptide Cloacaenodin Utilizes a Unique TonB-Dependent Transporter to Access Susceptible Bacteria	72
Correction to “Characterization of the Iron–Sulfur Cluster in the NCOA4 Fragment (383–522) and Its Interaction with Ferritin”	68
Multi-TACs: Targeting Solid Tumors with Multiple Immune Cell Co-engagers	63
Ferroptosis Inhibitors Suppress Prostaglandin Synthesis in Lipopolysaccharide-Stimulated Macrophages	60
Structural and Biochemical Insights into Lignin-Oxidizing Activity of Bacterial Peroxidases against Soluble Substrates and Kraft Lignin	59
Robust Chemoenzymatic Synthesis of Keratinimicin Aglycone Analogues Facilitated by the Structure and Selectivity of OxyB	57
In Situ Labeling of Pathogenic Tau Using Photo-Affinity Chemical Probes	57
Dynamic Regulation of 5-Formylcytidine on tRNA	54
Reengineering of Circularly Permuted Caspase-2 to Enhance Enzyme Stability and Enable Crystallographic Studies	51
Dichlorophenylpyridine-Based Molecules Inhibit Furin through an Induced-Fit Mechanism	50
Enzymatic Macrolactamization of mRNA Display Libraries for Inhibitor Selection	47
Enzymatic Pathway for Kupyaphore Degradation in Mycobacterium tuberculosis: Mechanism of Metal Homeostasis and Turnover	45
Target-Responsive DNA Hydrogels with Encapsulation and Release Properties Using Programmable CRISPR-Cas12a	45
Discovery and Validation of a Novel Class of Necroptosis Inhibitors Targeting RIPK1	45
Issue Publication Information	44
Issue Editorial Masthead	42
Biosynthesis of Physcion and Identification of an O-Methyltransferase with C6–OH Selectivity in Aspergillus chevalieri BYST01	42
Chemical Synthetic Lethality Screens Identify Selective Drug Combinations against Pseudomonas aeruginosa	42
Spontaneous Cleavage at Glu and Gln Residues in Long-Lived Proteins	41
Structure and Function of the β-Asp-Arg Polymerase Cyanophycin Synthetase 2	41

Deposition Bias of Chromatin Proteins Inverts under DNA Replication Stress Conditions	40
A Nonfunctional Halogenase Masquerades as an Aromatizing Dehydratase in Biosynthesis of Pyrrolic Polyketides by Type I Polyketide Synthases	40
Targeting IRAK3 for Degradation to Enhance IL-12 Pro-inflammatory Cytokine Production	39
HiBiT-SpyTag: A Minimal Tag for Covalent Protein Capture and Degrader Development	38
Spatiotemporal Proximity Labeling Tools to Track GlcNAc Sugar-Modified Functional Protein Hubs during Cellular Signaling	37
Repurposing of the RIPK1-Selective Benzo[1,4]oxazepin-4-one Scaffold for the Development of a Type III LIMK1/2 Inhibitor	36
An Inherent Difference between Serine and Threonine Phosphorylation: Phosphothreonine Strongly Prefers a Highly Ordered, Compact, Cyclic Conformation	36
Mechanistic Studies on Dehydration in Class V Lanthipeptides	35
A Robust α-l-Fucosidase from Prevotella nigrescens for Glycoengineering Therapeutic Antibodies	35
Analysis of the Valgamicin Biosynthetic Pathway Reveals a General Mechanism for Cyclopropanol Formation across Diverse Natural Product Scaffolds	35
Discovery of Small-Molecule Inhibitors of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer	35