OOIR: Observatory of International Research

Papers

(The H4-Index of ACS Chemical Biology is 32. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
A Useful Guide to Lectin Binding: Machine-Learning Directed Annotation of 57 Unique Lectin Specificities	140
m⁶A-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells	109
A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells	81
LPCAT3 Inhibitors Remodel the Polyunsaturated Phospholipid Content of Human Cells and Protect from Ferroptosis	75
Deorphanizing Caspase-3 and Caspase-9 Substrates In and Out of Apoptosis with Deep Substrate Profiling	74
SARS-CoV-2 RBD-Tetanus Toxoid Conjugate Vaccine Induces a Strong Neutralizing Immunity in Preclinical Studies	63
Modulation of Phosphoprotein Activity by Phosphorylation Targeting Chimeras (PhosTACs)	63
Brightening up Biology: Advances in Luciferase Systems for in Vivo Imaging	57
Near-Infrared Fluorescent Probes for the Detection of Cancer-Associated Proteases	55
The SARS-CoV-2 Programmed −1 Ribosomal Frameshifting Element Crystal Structure Solved to 2.09 Å Using Chaperone-Assisted RNA Crystallography	50
CH−π Interactions in Glycan Recognition	47
Genetic Encoding of Three Distinct Noncanonical Amino Acids Using Reprogrammed Initiator and Nonsense Codons	45
NanoClick: A High Throughput, Target-Agnostic Peptide Cell Permeability Assay	43
Roadmap for Optimizing and Broadening Antibody-Based PROTACs for Degradation of Cell Surface Proteins	43
Chalcogen Bonds Involving Selenium in Protein Structures	42
Plasmalogen Biosynthesis by Anaerobic Bacteria: Identification of a Two-Gene Operon Responsible for Plasmalogen Production in Clostridium perfringens	42
Selective Transformations of Carbohydrates Inspired by Radical-Based Enzymatic Mechanisms	40
Carbohydrate Sulfation As a Mechanism for Fine-Tuning Siglec Ligands	39
Nitrogen–Nitrogen Bond Formation Reactions Involved in Natural Product Biosynthesis	39
Spatiotemporal Control of Biology: Synthetic Photochemistry Toolbox with Far-Red and Near-Infrared Light	37
Attenuation of NLRP3 Inflammasome Activation by Indirubin-Derived PROTAC Targeting HDAC6	37
l-Threonine Transaldolase Activity Is Enabled by a Persistent Catalytic Intermediate	36
Structural Characterization of Degrader-Induced Ternary Complexes Using Hydrogen–Deuterium Exchange Mass Spectrometry and Computational Modeling: Implications for Structure-Based Design	36
Machine Learning Classifies Ferroptosis and Apoptosis Cell Death Modalities with TfR1 Immunostaining	35
CRISPR Screen Reveals BRD2/4 Molecular Glue-like Degrader via Recruitment of DCAF16	35

Development of a Red-Light-Controllable Nitric Oxide Releaser to Control Smooth Muscle Relaxation in Vivo	35
High-Throughput Activity Assay for Screening Inhibitors of the SARS-CoV-2 Mac1 Macrodomain	34
R-BIND 2.0: An Updated Database of Bioactive RNA-Targeting Small Molecules and Associated RNA Secondary Structures	33
Bioinformatics-Guided Expansion and Discovery of Graspetides	33
Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein–Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production	32
Chemical Screen for Vancomycin Antagonism Uncovers Probes of the Gram-Negative Outer Membrane	32
Identification of a Small Molecule That Enhances Ferroptosis via Inhibition of Ferroptosis Suppressor Protein 1 (FSP1)	32
A Probe for NLRP3 Inflammasome Inhibitor MCC950 Identifies Carbonic Anhydrase 2 as a Novel Target	32
Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome	32