OOIR: Observatory of International Research

Papers

(The H4-Index of ACS Chemical Biology is 33. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Introducing Our Authors	276
Introducing Our Authors	121
Discovery and Validation of a Novel Class of Necroptosis Inhibitors Targeting RIPK1	79
Enzymatic Pathway for Kupyaphore Degradation in Mycobacterium tuberculosis: Mechanism of Metal Homeostasis and Turnover	73
Multi-TACs: Targeting Solid Tumors with Multiple Immune Cell Co-engagers	69
Correction to “Characterization of the Iron–Sulfur Cluster in the NCOA4 Fragment (383–522) and Its Interaction with Ferritin”	67
Structure and Function of the β-Asp-Arg Polymerase Cyanophycin Synthetase 2	56
Discovery of Small-Molecule Inhibitors of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer	51
Enzymatic Macrolactamization of mRNA Display Libraries for Inhibitor Selection	50
Antimicrobial Lasso Peptide Cloacaenodin Utilizes a Unique TonB-Dependent Transporter to Access Susceptible Bacteria	50
Issue Publication Information	50
Issue Editorial Masthead	47
In Situ Labeling of Pathogenic Tau Using Photo-Affinity Chemical Probes	46
A Nonfunctional Halogenase Masquerades as an Aromatizing Dehydratase in Biosynthesis of Pyrrolic Polyketides by Type I Polyketide Synthases	44
Reengineering of Circularly Permuted Caspase-2 to Enhance Enzyme Stability and Enable Crystallographic Studies	43
Chemical Synthetic Lethality Screens Identify Selective Drug Combinations against Pseudomonas aeruginosa	43
Dynamic Regulation of 5-Formylcytidine on tRNA	42
Robust Chemoenzymatic Synthesis of Keratinimicin Aglycone Analogues Facilitated by the Structure and Selectivity of OxyB	41
Structural and Biochemical Insights into Lignin-Oxidizing Activity of Bacterial Peroxidases against Soluble Substrates and Kraft Lignin	41
A Robust α-l-Fucosidase from Prevotella nigrescens for Glycoengineering Therapeutic Antibodies	37
Repurposing of the RIPK1-Selective Benzo[1,4]oxazepin-4-one Scaffold for the Development of a Type III LIMK1/2 Inhibitor	37
Exploring Metalloproteome Remodeling in Calprotectin-Stressed Acinetobacter baumannii Using Chemoproteomics	36
Mechanistic Studies on Dehydration in Class V Lanthipeptides	36
Biosynthesis of Physcion and Identification of an O-Methyltransferase with C6–OH Selectivity in Aspergillus chevalieri BYST01	35
Dichlorophenylpyridine-Based Molecules Inhibit Furin through an Induced-Fit Mechanism	35

Target-Responsive DNA Hydrogels with Encapsulation and Release Properties Using Programmable CRISPR-Cas12a	35
Molecular Targeted Engagement of DPP9 in Rat Tissue Using CETSA, SP3 Processing, and Absolute Quantitation Mass Spectrometry	35
Spatiotemporal Proximity Labeling Tools to Track GlcNAc Sugar-Modified Functional Protein Hubs during Cellular Signaling	35
Simple Enzymatic Incorporation of 2′OMeU Nucleotide at the End of the Poly-A Tail for Enhancement of the mRNA Stability and Protein Expression	35
An Inherent Difference between Serine and Threonine Phosphorylation: Phosphothreonine Strongly Prefers a Highly Ordered, Compact, Cyclic Conformation	34
Targeting IRAK3 for Degradation to Enhance IL-12 Pro-inflammatory Cytokine Production	34
Photoactivatable Plant Hormone-Based Chemical Inducers of Proximity for In Vivo Applications	33
Ferroptosis Inhibitors Suppress Prostaglandin Synthesis in Lipopolysaccharide-Stimulated Macrophages	33
Phage Display Selection against a Mixture of Protein Targets	33
HiBiT-SpyTag: A Minimal Tag for Covalent Protein Capture and Degrader Development	33