Autophagy

Article	Citations
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1	1612
Mitochondria ROS and mitophagy in acute kidney injury	229
Ferritinophagy is involved in the zinc oxide nanoparticles-induced ferroptosis of vascular endothelial cells	215
Inhibiting NLRP3 inflammasome attenuates apoptosis in contrast-induced acute kidney injury through the upregulation of HIF1A and BNIP3-mediated mitophagy	188
How autophagy controls the intestinal epithelial barrier	170
Copper-dependent autophagic degradation of GPX4 drives ferroptosis	165
Copper metabolism in cell death and autophagy	151
The ménage à trois of autophagy, lipid droplets and liver disease	150
Tumor heterogeneity in autophagy-dependent ferroptosis	137
Autophagy in ovary and polycystic ovary syndrome: role, dispute and future perspective	133
Long noncoding RNA (lncRNA) EIF3J-DT induces chemoresistance of gastric cancer via autophagy activation	125
Ischemia-induced upregulation of autophagy preludes dysfunctional lysosomal storage and associated synaptic impairments in neurons	119
GPX4 in cell death, autophagy, and disease	118
PRDX1 activates autophagy via the PTEN-AKT signaling pathway to protect against cisplatin-induced spiral ganglion neuron damage	114
Acetylation in the regulation of autophagy	112
Full-coverage regulations of autophagy by ROS: from induction to maturation	111
Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells	108
MAPK1/3 kinase-dependent ULK1 degradation attenuates mitophagy and promotes breast cancer bone metastasis	106
HIF1A Alleviates compression-induced apoptosis of nucleus pulposus derived stem cells via upregulating autophagy	104
Regulation of PRKN-independent mitophagy	103
AMPK-dependent phosphorylation is required for transcriptional activation of TFEB and TFE3	102
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4	98
TXNIP/VDUP1 attenuates steatohepatitis via autophagy and fatty acid oxidation	97
Targeting autophagy in disease: established and new strategies	96
Crocetin promotes clearance of amyloid-β by inducing autophagy via the STK11/LKB1-mediated AMPK pathway	92

CUL3 (cullin 3)-mediated ubiquitination and degradation of BECN1 (beclin 1) inhibit autophagy and promote tumor progression	89
m6A reader YTHDC1 modulates autophagy by targeting SQSTM1 in diabetic skin	88
Regulation and function of autophagy in pancreatic cancer	85
Autophagy and ALS: mechanistic insights and therapeutic implications	84
Autophagy in age-related macular degeneration	83
The multifaceted regulation of mitophagy by endogenous metabolites	81
Autophagy alleviates hypoxia-induced blood-brain barrier injury via regulation of CLDN5 (claudin 5)	81
CDK9 inhibition blocks the initiation of PINK1-PRKN-mediated mitophagy by regulating the SIRT1-FOXO3-BNIP3 axis and enhances the therapeutic effects involving mitochondrial dysfunction in hepatocellul	79
Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanism involving activation of TFEB (transcription factor EB)	78
Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3	76
The role of mitophagy in the regulation of mitochondrial energetic status in neurons	73
Manipulation of autophagy by SARS-CoV-2 proteins	72
DCN released from ferroptotic cells ignites AGER-dependent immune responses	71
Rapamycin prevents spontaneous abortion by triggering decidual stromal cell autophagy-mediated NK cell residence	71
Mitochondrial autophagy and cell survival is regulated by the circadian Clock gene in cardiac myocytes during ischemic stress	71
FOXG1 promotes aging inner ear hair cell survival through activation of the autophagy pathway	69
Hydrogen peroxide mediates spermidine-induced autophagy to alleviate salt stress in cucumber	69
Newcastle disease virus degrades SIRT3 via PINK1-PRKN-dependent mitophagy to reprogram energy metabolism in infected cells	68
TMEM164 is a new determinant of autophagy-dependent ferroptosis	66
Tubular cells produce FGF2 via autophagy after acute kidney injury leading to fibroblast activation and renal fibrosis	66
SIRT1 – a new mammalian substrate of nuclear autophagy	66
Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD	64
Vitamin D-VDR (vitamin D receptor) regulates defective autophagy in renal tubular epithelial cell in streptozotocin-induced diabetic mice via the AMPK pathway	63
Trehalose causes low-grade lysosomal stress to activate TFEB and the autophagy-lysosome biogenesis response	62
Alternative mitochondrial quality control mediated by extracellular release	62
C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels	61
The role of autophagy in bone metabolism and clinical significance	61
Autophagy inhibition mediated by MCOLN1/TRPML1 suppresses cancer metastasis via regulating a ROS-driven TP53/p53 pathway	60
Combination of autophagy and NFE2L2/NRF2 activation as a treatment approach for neuropathic pain	60
Autophagy regulates differentiation of ovarian granulosa cells through degradation of WT1	59
AMPK protects against alcohol-induced liver injury through UQCRC2 to up-regulate mitophagy	58
USP5 attenuates NLRP3 inflammasome activation by promoting autophagic degradation of NLRP3	58
The ORF7a protein of SARS-CoV-2 initiates autophagy and limits autophagosome-lysosome fusion via degradation of SNAP29 to promote virus replication	56
Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2R1441Gmice	55
Identification of HPCAL1 as a specific autophagy receptor involved in ferroptosis	55
The influence of circular RNAs on autophagy and disease progression	53
HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway	52
Antidepressant drug sertraline modulates AMPK-MTOR signaling-mediated autophagy via targeting mitochondrial VDAC1 protein	51
TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy	51
Selective autophagy receptor SQSTM1/ p62 inhibits Seneca Valley virus replication by targeting viral VP1 and VP3	50
RAB7 activity is required for the regulation of mitophagy in oocyte meiosis and oocyte quality control during ovarian aging	50
Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death	48
Enhanced viability and function of mesenchymal stromal cell spheroids is mediated via autophagy induction	47
M. tuberculosis PknG manipulates host autophagy flux to promote pathogen intracellular survival	47
Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders	47
Emerging views of OPTN (optineurin) function in the autophagic process associated with disease	47
Augmenting ATG14 alleviates atherosclerosis and inhibits inflammation via promotion of autophagosome-lysosome fusion in macrophages	45
PINK1-PRKN mediated mitophagy: differences between in vitro and in vivo models	44
CGAS is a micronucleophagy receptor for the clearance of micronuclei	44
BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes	44

Impaired lipophagy induced-microglial lipid droplets accumulation contributes to the buildup of TREM1 in diabetes-associated cognitive impairment	43
ATF3 -activated accelerating effect of LINC00941/lncIAPF on fibroblast-to-myofibroblast differentiation by blocking autophagy depending on ELAVL1/HuR in pulmonary fibrosis	42
LAMP3 inhibits autophagy and contributes to cell death by lysosomal membrane permeabilization	41
HBx induces hepatocellular carcinogenesis through ARRB1-mediated autophagy to drive the G1/S cycle	40
Phosphoregulation of the autophagy machinery by kinases and phosphatases	40
Muscle-generated BDNF (brain derived neurotrophic factor) maintains mitochondrial quality control in female mice	40
Rapamycin relieves the cataract caused by ablation of Gja8b through stimulating autophagy in zebrafish	40
Protective effect of the tunneling nanotube-TNFAIP2/M-sec system on podocyte autophagy in diabetic nephropathy	40
Spermidine-induced hypusination preserves mitochondrial and cognitive function during aging	40
Autophagy in metabolism and quality control: opposing, complementary or interlinked functions?	39
Negative pressure wound therapy improves bone regeneration by promoting osteogenic differentiation via the AMPK-ULK1-autophagy axis	39
The exploitation of host autophagy and ubiquitin machinery by Mycobacterium tuberculosis in shaping immune responses and host defense during infection	39
ESRRA (estrogen related receptor alpha) is a critical regulator of intestinal homeostasis through activation of autophagic flux via gut microbiota	39
Piperine promotes autophagy flux by P2RX4 activation in SNCA /α-synuclein-induced Parkinson disease model	39
Increased mitophagy protects cochlear hair cells from aminoglycoside-induced damage	39
Inhibition of PLA2G4E/cPLA2 promotes survival of random skin flaps by alleviating Lysosomal membrane permeabilization-Induced necroptosis	38
Degradation of the NOTCH intracellular domain by elevated autophagy in osteoblasts promotes osteoblast differentiation and alleviates osteoporosis	38
ATM orchestrates ferritinophagy and ferroptosis by phosphorylating NCOA4	38
Hydrogen sulfide-induced GAPDH sulfhydration disrupts the CCAR2-SIRT1 interaction to initiate autophagy	38
MCOLN1/TRPML1 finely controls oncogenic autophagy in cancer by mediating zinc influx	37
CAMK2/CaMKII activates MLKL in short-term starvation to facilitate autophagic flux	37
Defective autophagy contributes to endometrial epithelial-mesenchymal transition in intrauterine adhesions	37
Targeting glutamine metabolism and autophagy: the combination for prostate cancer radiosensitization	36
TET2 regulates osteoclastogenesis by modulating autophagy in OVX-induced bone loss	36
Autophagic lysosome reformation in health and disease	36
ATI1 (ATG8-interacting protein 1) and ATI2 define a plant starvation-induced reticulophagy pathway and serve as MSBP1/MAPR5 cargo receptors	36
Lipotoxicity-induced STING1 activation stimulates MTORC1 and restricts hepatic lipophagy	36
Exploring the role of non-coding RNAs in autophagy	36
AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability	36
Macrophage mitochondrial MFN2 (mitofusin 2) links immune stress and immune response through reactive oxygen species (ROS) production	36
A VASt-domain protein regulates autophagy, membrane tension, and sterol homeostasis in rice blast fungus	35
Mt-Keima detects PINK1-PRKN mitophagy in vivo with greater sensitivity than mito-QC	35
GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma via modulation of lysosomal functions	34
LC3 subfamily in cardiolipin-mediated mitophagy: a comparison of the LC3A, LC3B and LC3C homologs	34
BNIP3-dependent mitophagy promotes cytosolic localization of LC3B and metabolic homeostasis in the liver	34
The spectrum of neurodevelopmental, neuromuscular and neurodegenerative disorders due to defective autophagy	33
Autophagy restricts mitochondrial DNA damage-induced release of ENDOG (endonuclease G) to regulate genome stability	33
Inhibition of USP14 influences alphaherpesvirus proliferation by degrading viral VP16 protein via ER stress-triggered selective autophagy	32
Stress granule homeostasis is modulated by TRIM21-mediated ubiquitination of G3BP1 and autophagy-dependent elimination of stress granules	32
A defective lysophosphatidic acid-autophagy axis increases miscarriage risk by restricting decidual macrophage residence	32
PLK1 (polo like kinase 1)-dependent autophagy facilitates gefitinib-induced hepatotoxicity by degrading COX6A1 (cytochrome c oxidase subunit 6A1)	32
CD36 and LC3B initiated autophagy in B cells regulates the humoral immune response	32
AMBRA1 regulates mitophagy by interacting with ATAD3A and promoting PINK1 stability	31
Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels	31
Protein complexes and neighborhoods driving autophagy	31
Analysis of Drosophila Atg8 proteins reveals multiple lipidation-independent roles	31
Lipotoxicity reduces DDX58/Rig-1 expression and activity leading to impaired autophagy and cell death	30
FLT4/VEGFR3 activates AMPK to coordinate glycometabolic reprogramming with autophagy and inflammasome activation for bacterial elimination	30
LGALS3 (galectin 3) mediates an unconventional secretion of SNCA/α-synuclein in response to lysosomal membrane damage by the autophagic-lysosomal pathway in human midbrain dopamine neurons	30
Extracellular SQSTM1 exacerbates acute pancreatitis by activating autophagy-dependent ferroptosis	30
Glutamine, MTOR and autophagy: a multiconnection relationship	30
SARS-CoV-2 ORF3a induces RETREG1/FAM134B-dependent reticulophagy and triggers sequential ER stress and inflammatory responses during SARS-CoV-2 infection	30
PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery	30
The chaperone-assisted selective autophagy complex dynamics and dysfunctions	29
OTUD7B deubiquitinates SQSTM1/p62 and promotes IRF3 degradation to regulate antiviral immunity	29
Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiology	29
Genome-Scale CRISPR screen identifies LAPTM5 driving lenvatinib resistance in hepatocellular carcinoma	29
Outer membrane vesicles produced by pathogenic strains of Escherichia coli block autophagic flux and exacerbate inflammasome activation	28
WDR45, one gene associated with multiple neurodevelopmental disorders	28
Chaperone-mediated autophagy controls the turnover of E3 ubiquitin ligase MARCHF5 and regulates mitochondrial dynamics	28
TRAF6 autophagic degradation by avibirnavirus VP3 inhibits antiviral innate immunity via blocking NFKB/NF-κB activation	28
Autophagy loss impedes cancer-associated fibroblast activation via downregulating proline biosynthesis	28
Microglial phagocytosis dysfunction in stroke is driven by energy depletion and induction of autophagy	28
ALDOA maintains NLRP3 inflammasome activation by controlling AMPK activation	28
WIPI1 promotes fission of endosomal transport carriers and formation of autophagosomes through distinct mechanisms	28
Acetylation of SCFD1 regulates SNARE complex formation and autophagosome-lysosome fusion	28
Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1G93A astrocytes	28
Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine	27
HPV sensitizes OPSCC cells to cisplatin-induced apoptosis by inhibiting autophagy through E7-mediated degradation of AMBRA1	27
GLIPR2 is a negative regulator of autophagy and the BECN1-ATG14-containing phosphatidylinositol 3-kinase complex	27
Melatonin attenuates sepsis-induced acute kidney injury by promoting mitophagy through SIRT3-mediated TFAM deacetylation	27
Macrophages target Listeria monocytogenes by two discrete non-canonical autophagy pathways	27
Tumor-derived lactate promotes resistance to bevacizumab treatment by facilitating autophagy enhancer protein RUBCNL expression through histone H3 lysine 18 lactylation (H3K18la) in colorectal cancer	27
Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models	27
TOR and MAP kinase pathways synergistically regulate autophagy in response to nutrient depletion in fission yeast	27
C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy	26
Chaperone-mediated autophagy: a gatekeeper of neuronal proteostasis	26
BLOC1S1/GCN5L1/BORCS1 is a critical mediator for the initiation of autolysosomal tubulation	26
Vascular smooth muscle cell-derived hydrogen sulfide promotes atherosclerotic plaque stability via TFEB (transcription factor EB)-mediated autophagy	26
Mitophagy initiates retrograde mitochondrial-nuclear signaling to guide retinal pigment cell heterogeneity	26

Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease	26
The nucleoprotein of influenza A virus inhibits the innate immune response by inducing mitophagy	26
Extracellular SQSTM1 as an inflammatory mediator	25
Inhibition of autophagy in microglia and macrophages exacerbates innate immune responses and worsens brain injury outcomes	25
TRIM44 links the UPS to SQSTM1/p62-dependent aggrephagy and removing misfolded proteins	25
Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations	25
USP19 (ubiquitin specific peptidase 19) promotes TBK1 (TANK-binding kinase 1) degradation via chaperone-mediated autophagy	25
Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression	25
Autophagic degradation of CCN2 (cellular communication network factor 2) causes cardiotoxicity of sunitinib	25
C53 is a cross-kingdom conserved reticulophagy receptor that bridges the gap betweenselective autophagy and ribosome stalling at the endoplasmic reticulum	25
Measurement of autophagic flux in humans: an optimized method for blood samples	25
LAMP2A, LAMP2B and LAMP2C: similar structures, divergent roles	25
Highlights in the fight against COVID-19: does autophagy play a role in SARS-CoV-2 infection?	24
Exendin-4 stimulates autophagy in pancreatic β-cells via the RAPGEF/EPAC-Ca2+-PPP3/calcineurin-TFEB axis	24
STING1 is essential for an RNA-virus triggered autophagy	24
Upregulation of brain cholesterol levels inhibits mitophagy in Alzheimer disease	23
Coxsackievirus B3 targets TFEB to disrupt lysosomal function	23
Acetylation-dependent regulation of TPD52 isoform 1 modulates chaperone-mediated autophagy in prostate cancer	23
Interplay of energy metabolism and autophagy	23
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation	23
Regulation of oxidative stress-induced autophagy by ATG9A ubiquitination	23
Identification of an autoinhibitory, mitophagy-inducing peptide derived from the transmembrane domain of USP30	23
2AB protein of Senecavirus A antagonizes selective autophagy and type I interferon production by degrading LC3 and MARCHF8	23
Quantitative proteomic analysis of temporal lysosomal proteome and the impact of the KFERQ-like motif and LAMP2A in lysosomal targeting	22
UXT attenuates the CGAS-STING1 signaling by targeting STING1 for autophagic degradation	22
The Epstein-Barr virus deubiquitinase BPLF1 targets SQSTM1/p62 to inhibit selective autophagy	22
Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism	22
LRRK2 is required for CD38-mediated NAADP-Ca2+signaling and the downstream activation of TFEB (transcription factor EB) in immune cells	22
Targeting MCL1 to induce mitophagy is a potential therapeutic strategy for Alzheimer disease	22
Mycobacterium bovis induces mitophagy to suppress host xenophagy for its intracellular survival	22
Mitochondrial depolarization after acute ethanol treatment drives mitophagy in living mice	22
TOLLIP-mediated autophagic degradation pathway links the VCP-TMEM63A-DERL1 signaling axis to triple-negative breast cancer progression	22
The mitophagy receptor BNIP3 is critical for the regulation of metabolic homeostasis and mitochondrial function in the nucleus pulposus cells of the intervertebral disc	22
Tegument protein UL21 of alpha-herpesvirus inhibits the innate immunity by triggering CGAS degradation through TOLLIP-mediated selective autophagy	22
Epg5 deficiency leads to primary ovarian insufficiency due to WT1 accumulation in mouse granulosa cells	22
­­Atg9 interactions via its transmembrane domains are required for phagophore expansion during autophagy	21
The conformational and mutational landscape of the ubiquitin-like marker for autophagosome formation in cancer	21
Celastrol, a TFEB (transcription factor EB) agonist, is a promising drug candidate for Alzheimer disease	21
Neutrophil autophagy and NETosis in COVID-19: perspectives	21
RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis	21
Blockage of autophagosome-lysosome fusion through SNAP29 O-GlcNAcylation promotes apoptosis via ROS production	21
Chemical modulation of SQSTM1/p62-mediated xenophagy that targets a broad range of pathogenic bacteria	21
PEX13 prevents pexophagy by regulating ubiquitinated PEX5 and peroxisomal ROS	21
Microglial mitophagy integrates the microbiota-gut-brain axis to restrain neuroinflammation during neurotropic herpesvirus infection	21
Involvement of autophagy in exacerbation of eosinophilic airway inflammation in a murine model of obese asthma	21
Abnormal triaging of misfolded proteins by adult neuronal ceroid lipofuscinosis-associated DNAJC5/CSPα mutants causes lipofuscin accumulation	20
NPPA/atrial natriuretic peptide is an extracellular modulator of autophagy in the heart	20
TMEM41B and VMP1 are phospholipid scramblases	20
Vacuolar processing enzyme translocates to the vacuole through the autophagy pathway to induce programmed cell death	20
Targeting autophagy as a therapeutic strategy to prevent dopamine neuron loss in early stages of Alzheimer disease	20
Garcinia cambogia attenuates adipogenesis by affecting CEBPB and SQSTM1/p62-mediated selective autophagic degradation of KLF3 through RPS6KA1 and STAT3 suppression	20
Treatments targeting autophagy ameliorate the age-related macular degeneration phenotype in mice lacking APOE (apolipoprotein E)	20
Targeting lipophagy in macrophages improves repair in multiple sclerosis	20
SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes	20
Reduced secretion of LCN2 (lipocalin 2) from reactive astrocytes through autophagic and proteasomal regulation alleviates inflammatory stress and neuronal damage	20
Isoginkgetin, a potential CDK6 inhibitor, suppresses SLC2A1/GLUT1 enhancer activity to induce AMPK-ULK1-mediated cytotoxic autophagy in hepatocellular carcinoma	20
TDRD7 participates in lens development and spermiogenesis by mediating autophagosome maturation	20
Rice black-streaked dwarf virus P10 promotes phosphorylation of GAPDH (glyceraldehyde-3-phosphate dehydrogenase) to induce autophagy in Laodelphax striatellus	20
Endolysosome and autophagy dysfunction in Alzheimer disease	20
HIV-1 Vpr protein impairs lysosome clearance causing SNCA/alpha-synuclein accumulation in neurons	20
The polymorphism L412F in TLR3 inhibits autophagy and is a marker of severe COVID-19 in males	20
VCP/p97 cofactor UBXN1/SAKS1 regulates mitophagy by modulating MFN2 removal from mitochondria	20
Salicylic acid and the viral virulence factor 2b regulate the divergent roles of autophagy during cucumber mosaic virus infection	20
The Acid Gate in the Lysosome	20
Pathogen-induced autophagy regulates monolignol transport and lignin formation in plant immunity	19
The role of ATG16L2 in autophagy and disease	19
Vacuole fragmentation depends on a novel Atg18-containing retromer-complex	19
Tumor-derived CTF1 (cardiotrophin 1) is a critical mediator of stroma-assisted and autophagy-dependent breast cancer cell migration, invasion and metastasis	19
Enhanced autophagy in Becn1F121A/F121A knockin mice counteracts aging-related neural stem cell exhaustion and dysfunction	19
CREG1 improves the capacity of the skeletal muscle response to exercise endurance via modulation of mitophagy	19
The role of LC3B in autophagy as an RNA-binding protein	19
SQSTM1, lipid droplets and current state of their lipophagy affairs	19
International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis	19
TNK2/ACK1-mediated phosphorylation of ATP5F1A (ATP synthase F1 subunit alpha) selectively augments survival of prostate cancer while engendering mitochondrial vulnerability	19
MED1 mediator subunit is a key regulator of hepatic autophagy and lipid metabolism	19
Carbon starvation, senescence and specific mitochondrial stresses, but not nitrogen starvation and general stresses, are major triggers for mitophagy in Arabidopsis	18
Thrombolysis by PLAT/tPA increases serum free IGF1 leading to a decrease of deleterious autophagy following brain ischemia	18
Protein disulfide isomerases (PDIs) negatively regulate ebolavirus structural glycoprotein expression in the endoplasmic reticulum (ER) via the autophagy-lysosomal pathway	18
The Crohn Disease-associated ATG16L1T300A polymorphism regulates inflammatory responses by modulating TLR- and NLR-mediated signaling	18
Ion Channels and Transporters in Autophagy	18
USP22 suppresses the NLRP3 inflammasome by degrading NLRP3 via ATG5-dependent autophagy	18
Targeting lipid droplets for autophagic degradation by ATTEC	18
Selective autophagic degradation of ACLY (ATP citrate lyase) maintains citrate homeostasis and promotes oocyte maturation	18
The lipid basis of cell death and autophagy	18
Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress	18
RTN4/Nogo-A-S1PR2 negatively regulates angiogenesis and secondary neural repair through enhancing vascular autophagy in the thalamus after cerebral cortical infarction	18
Targeting mitophagy to promote apoptosis is a potential therapeutic strategy for cancer	18
WLS/wntless is essential in controlling dendritic cell homeostasis via a WNT signaling-independent mechanism	18
Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic lysosome reformation	18
Lysosomal targeting of autophagosomes by the TECPR domain of TECPR2	18
Phosphatidic acid suppresses autophagy through competitive inhibition by binding GAPC (glyceraldehyde-3-phosphate dehydrogenase) and PGK (phosphoglycerate kinase) proteins	18
AHCYL1 senses SAH to inhibit autophagy through interaction with PIK3C3 in an MTORC1-independent manner	17
A tecpr2 knockout mouse exhibits age-dependent neuroaxonal dystrophy associated with autophagosome accumulation	17
The human vault RNA enhances tumorigenesis and chemoresistance through the lysosome in hepatocellular carcinoma	17
Regulation of TFEB nuclear localization by HSP90AA1 promotes autophagy and longevity	17