OOIR: Observatory of International Research

Papers

(The median citation count of Annual Review of Pathology-Mechanisms of Disease is 20. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Pathogenic Mechanisms Underlying Idiopathic Pulmonary Fibrosis	410
Reflections on a Career in Pediatric Neuropathology, with a Note of Gratitude	326
Apolipoprotein E and Alzheimer's Disease: Findings, Hypotheses, and Potential Mechanisms	204
B Cell Responses to the Placenta and Fetus	199
	197
RNA Damage Responses in Cellular Homeostasis, Genome Stability, and Disease	173
Cystic Fibrosis and the Cells of the Airway Epithelium: What Are Ionocytes and What Do They Do?	161
Recent Advances in Understanding of Pathogenesis of Alcohol-Associated Liver Disease	148
Circadian Clocks, Daily Stress, and Neurodegenerative Disease	140
Pathogenesis of Triple-Negative Breast Cancer	104
	103
Neuroepithelial Interactions in Cancer	93
Tuft Cells: Context- and Tissue-Specific Programming for a Conserved Cell Lineage	91
Pathogenesis of Germinal Matrix Hemorrhage: Insights from Single-Cell Transcriptomics	87
Neutrophils in Physiology and Pathology	86
Tumor-Derived Extracellular Vesicles: Multifunctional Entities in the Tumor Microenvironment	79
Engineering β Cell Replacement Therapies for Type 1 Diabetes: Biomaterial Advances and Considerations for Macroscale Constructs	78
Immune Dysregulation in Obesity	74
Pathogenesis of Focal Segmental Glomerulosclerosis and Related Disorders	67
The Immunobiology and Pathogenesis of Celiac Disease	62
The Immune Response in Multiple Sclerosis	61
After the Storm: Regeneration, Repair, and Reestablishment of Homeostasis Between the Alveolar Epithelium and Innate Immune System Following Viral Lung Injury	54
My Journey	54
Molecular Pathology of Laminopathies	52
Cancer as a Disease of Development Gone Awry	51

ENPP1 in Blood and Bone: Skeletal and Soft Tissue Diseases Induced by ENPP1 Deficiency	51
Genetics and Pathogenesis of Dystonia	49
	47
DNA Methylation Profiling: An Emerging Paradigm for Cancer Diagnosis	44
Role of Fungi in Tumorigenesis: Promises and Challenges	42
Somatic Mosaicism in Brain Disorders	42
Multiplexed Ion Beam Imaging: Insights into Pathobiology	41
Hypoxia-Induced Signaling in Gut and Liver Pathobiology	40
The Pathogenesis of African Trypanosomiasis	40
Inherited Predispositions to Myeloid Neoplasms: Pathogenesis and Clinical Implications	37
Polycystic Liver Disease: Advances in Understanding and Treatment	34
Within-Host Evolution of Bacterial Pathogens in Acute and Chronic Infection	34
Innate Immunity and Cancer Pathophysiology	31
Metabolism and Colorectal Cancer	31
Haploinsufficient Transcription Factors in Myeloid Neoplasms	26
Unraveling Mechanisms of Genetic Risks in Metabolic Dysfunction–Associated Steatotic Liver Diseases: A Pathway to Precision Medicine	26
Tumor Microenvironment in Pancreatic Cancer Pathogenesis and Therapeutic Resistance	24
Spatiotemporal Metabolic Liver Zonation and Consequences on Pathophysiology	24
Cutaneous Squamous Cell Carcinoma: The Frontier of Cancer Immunoprevention	23
Targeting Protein–Protein Interactions in Hematologic Malignancies	21
Choroid Plexus Pathophysiology	20