OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Chemical Biology is 64. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Making a 6mA demethylase	219
Chemical targeting of amyloids	199
To TnpB or not TnpB? Cas12 is the answer	192
Channeling kynurenine	182
Detecting features of antibody structure through their mediator-accessible redox activities	179
A sulfate amuse-bouche	174
Cyclic signature	169
Surviving salt stress	168
Development of cyclic peptides that can be administered orally to inhibit disease targets	149
A vicious cycle	146
Flipping the polarity switch	142
Sterol homeostasis in yeast	141
Altering the cap	135
Sensing the air	130
Seeing the retention	114
Assembly-activated aggregation	111
Publisher Correction: Accelerated RNA detection using tandem CRISPR nucleases	106
E2–Ub-R74G strategy reveals E2-specific ubiquitin conjugation profiles in live cells	106
Bacteria lose a pep in their step	104
Calcium-gated potassium channel blockade via membrane-facing fenestrations	101
Determining the role of peroxidation of subcellular lipid membranes in ferroptosis	101
Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms	100
Chemigenetic indicators based on synthetic chelators and green fluorescent protein	98
Chemical genomics with pyrvinium identifies C1orf115 as a regulator of drug efflux	96
A class of anti-inflammatory lipids decrease with aging in the central nervous system	95

Rationally seeded computational protein design of ɑ-helical barrels	93
An engineered trafficking biosensor reveals a role for DNAJC13 in DOR downregulation	92
Characterization of a patient-derived variant of GPX4 for precision therapy	90
Artificial intelligence foundation for therapeutic science	89
Ubiquitin-specific proximity labeling for the identification of E3 ligase substrates	89
The landscape of targets and lead molecules for remyelination	84
Author Correction: ML-enhanced peroxisome capacity enables compartmentalization of multienzyme pathway	83
Facile generation of drug-like conformational antibodies specific for amyloid fibrils	83
Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability	82
Lysosome-targeting chimeras evolve	81
Programmable living assembly of materials by bacterial adhesion	81
Lysine l-lactylation is the dominant lactylation isomer induced by glycolysis	80
Small-molecule trapping of an RNA-binding protein blocks cancer cell growth	79
Seismic shift	79
The core of the matter	79
Inter-kingdom electromechanical communication	79
Shape matching	78
Controlling sulfation	77
Brake disposal	77
Running through the blocks	75
Site-specific encoding of photoactivity and photoreactivity into antibody fragments	74
A high-throughput screening platform for enzymes active on mucin-type O-glycoproteins	73
An optimized bioluminescent substrate for non-invasive imaging in the brain	72
Peptides hit the catalysis walk	72
Small molecule targeting of chromatin writers in cancer	72
Badminton at nanoscale	72
Tuned out	70
M24B aminopeptidase inhibitors selectively activate the CARD8 inflammasome	69
Programmed RNA editing with an evolved bacterial adenosine deaminase	69
Engineering CAR-T cells to activate small-molecule drugs in situ	68
A wrench in the motor	67
Making transient complexes stick	67
Discovery and molecular basis of subtype-selective cyclophilin inhibitors	66
Visualizing drug effects over time in live animals using optical pharmacodynamics	66
Functional profiling of serine, threonine and tyrosine sites	66
Endogenous currents in HEK 293 cells are inhibited by memantine	66
Structure-based investigation of fluorogenic Pepper aptamer	65
Small molecule inhibits KCNQ channels with a non-blocking mechanism	65
Etoposide promotes DNA loop trapping and barrier formation by topoisomerase II	65
Open-ended molecular recording of sequential cellular events into DNA	64