Cell Metabolism

(The TQCC of Cell Metabolism is 121. The table below lists those papers that are above that threshold based on CrossRef citation counts. The publications cover those that have been published in the past four years, i.e., from 2019-03-01 to 2023-03-01.)
Macrophages and Metabolism in the Tumor Microenvironment597
Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake572
Improvement of Insulin Sensitivity after Lean Donor Feces in Metabolic Syndrome Is Driven by Baseline Intestinal Microbiota Composition531
Autophagy and Tumor Metabolism492
Epigenetics in Human Obesity and Type 2 Diabetes354
Extracellular miRNAs: From Biomarkers to Mediators of Physiology and Disease327
New Advances in Adaptive Thermogenesis: UCP1 and Beyond325
Time-Restricted Feeding Prevents Obesity and Metabolic Syndrome in Mice Lacking a Circadian Clock311
Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential302
Cholesterol Induces CD8+ T Cell Exhaustion in the Tumor Microenvironment287
Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis282
NAD+ in Brain Aging and Neurodegenerative Disorders279
A Breakdown in Metabolic Reprogramming Causes Microglia Dysfunction in Alzheimer's Disease249
Intermittent Fasting Confers Protection in CNS Autoimmunity by Altering the Gut Microbiota245
The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D245
Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility241
Mechanisms and Implications of Metabolic Heterogeneity in Cancer235
Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids218
Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer216
LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation214
GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans213
Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids210
Bacterial Metabolism and Antibiotic Efficacy208
Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis208
SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion204
Etomoxir Actions on Regulatory and Memory T Cells Are Independent of Cpt1a-Mediated Fatty Acid Oxidation204
Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis203
Anatomical, Physiological, and Functional Diversity of Adipose Tissue199
Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway198
Acceleration of β Cell Aging Determines Diabetes and Senolysis Improves Disease Outcomes193
Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring191
Medicine in the Fourth Dimension190
Fatty Liver Disease Caused by High-Alcohol-Producing Klebsiella pneumoniae184
Lipolysis in Brown Adipocytes Is Not Essential for Cold-Induced Thermogenesis in Mice182
The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity182
Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans182
Hallmarks of Endothelial Cell Metabolism in Health and Disease180
Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes176
Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice176
Peripheral ghrelin transmits orexigenic signals through the noradrenergic pathway from the hindbrain to the hypothalamus173
Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression171
Profound Perturbation of the Metabolome in Obesity Is Associated with Health Risk168
Exercise-Induced Changes in Visceral Adipose Tissue Mass Are Regulated by IL-6 Signaling: A Randomized Controlled Trial165
Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma161
Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration159
A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation159
Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair158
Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy158
A Map of Human Type 1 Diabetes Progression by Imaging Mass Cytometry155
Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation155
Daily Fasting Improves Health and Survival in Male Mice Independent of Diet Composition and Calories153
Watch What You (Self-) Eat: Autophagic Mechanisms that Modulate Metabolism150
CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress148
Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction147
A PDGFRα-Mediated Switch toward CD9high Adipocyte Progenitors Controls Obesity-Induced Adipose Tissue Fibrosis145
Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells143
Partial Leptin Reduction as an Insulin Sensitization and Weight Loss Strategy140
Serine Metabolism Supports Macrophage IL-1β Production138
Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis138
Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis136
Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development135
The Mouse Microbiome Is Required for Sex-Specific Diurnal Rhythms of Gene Expression and Metabolism134
A Dozen Years of Discovery: Insights into the Physiology and Pharmacology of FGF21131
Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A130
An Adipose Tissue Atlas: An Image-Guided Identification of Human-like BAT and Beige Depots in Rodents129
Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity128
Increased Serine Synthesis Provides an Advantage for Tumors Arising in Tissues Where Serine Levels Are Limiting127
Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis126
Time of Exercise Specifies the Impact on Muscle Metabolic Pathways and Systemic Energy Homeostasis125
Multiplexed In Situ Imaging Mass Cytometry Analysis of the Human Endocrine Pancreas and Immune System in Type 1 Diabetes125
Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions124
Conventional and Neo-antigenic Peptides Presented by β Cells Are Targeted by Circulating Naïve CD8+ T Cells in Type 1 Diabetic and Healthy Donors123
Mitochondria Bound to Lipid Droplets: Where Mitochondrial Dynamics Regulate Lipid Storage and Utilization121