Cell Metabolism

Papers
(The H4-Index of Cell Metabolism is 98. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-02-01 to 2024-02-01.)
ArticleCitations
Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes1090
The Metabolic Underpinnings of Ferroptosis547
Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis444
AMPK and TOR: The Yin and Yang of Cellular Nutrient Sensing and Growth Control407
In-Hospital Use of Statins Is Associated with a Reduced Risk of Mortality among Individuals with COVID-19373
Benefits of Metformin in Attenuating the Hallmarks of Aging357
Omics-Driven Systems Interrogation of Metabolic Dysregulation in COVID-19 Pathogenesis355
The hallmarks of cancer metabolism: Still emerging329
CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability318
Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation302
Mitochondrial Metabolism as a Target for Cancer Therapy297
The Role of HIF in Immunity and Inflammation281
The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation268
Effects of 4- and 6-h Time-Restricted Feeding on Weight and Cardiometabolic Health: A Randomized Controlled Trial in Adults with Obesity265
Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells265
Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity244
Amino Assets: How Amino Acids Support Immunity238
Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury221
Exosomes as mediators of intercellular crosstalk in metabolism221
The Gut Microbiota in Prediabetes and Diabetes: A Population-Based Cross-Sectional Study217
Defined p16High Senescent Cell Types Are Indispensable for Mouse Healthspan217
SARS-CoV-2 infects human pancreatic β cells and elicits β cell impairment211
Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function206
Endothelial Lactate Controls Muscle Regeneration from Ischemia by Inducing M2-like Macrophage Polarization205
A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells204
An Acetylation Switch of the NLRP3 Inflammasome Regulates Aging-Associated Chronic Inflammation and Insulin Resistance201
Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets198
Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming192
Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice186
Ultrasensitive Genetically Encoded Indicator for Hydrogen Peroxide Identifies Roles for the Oxidant in Cell Migration and Mitochondrial Function184
SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition184
Human Brown Adipocyte Thermogenesis Is Driven by β2-AR Stimulation173
Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism172
SCENITH: A Flow Cytometry-Based Method to Functionally Profile Energy Metabolism with Single-Cell Resolution171
Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming171
Diabetes, obesity, metabolism, and SARS-CoV-2 infection: the end of the beginning170
Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes170
Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects168
Why does obesity cause diabetes?165
The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine163
Microbiota-derived acetate enables the metabolic fitness of the brain innate immune system during health and disease158
Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis158
Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity156
FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption156
The Power of Plasticity—Metabolic Regulation of Hepatic Stellate Cells153
Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes153
Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress150
Gut-Resident Lactobacilli Activate Hepatic Nrf2 and Protect Against Oxidative Liver Injury149
Impairment of Glycolysis-Derived l-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer’s Disease149
Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity148
Changing global epidemiology of liver cancer from 2010 to 2019: NASH is the fastest growing cause of liver cancer145
Plasticity of Epididymal Adipose Tissue in Response to Diet-Induced Obesity at Single-Nucleus Resolution145
A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis142
The Gut Microbiota at the Service of Immunometabolism141
Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy140
Quantitative Fluxomics of Circulating Metabolites138
Positive feedback regulation of microglial glucose metabolism by histone H4 lysine 12 lactylation in Alzheimer’s disease134
Non-canonical Glutamate-Cysteine Ligase Activity Protects against Ferroptosis132
Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis130
SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells130
MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice128
GDF15 Induces Anorexia through Nausea and Emesis128
Astrocyte-neuron metabolic cooperation shapes brain activity127
Expression of SARS-CoV-2 Entry Factors in the Pancreas of Normal Organ Donors and Individuals with COVID-19126
The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure124
Glutamine Links Obesity to Inflammation in Human White Adipose Tissue123
Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance122
NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion122
Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway121
Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy120
The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling119
A High-Density Human Mitochondrial Proximity Interaction Network117
Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth116
Mechanoresponsive metabolism in cancer cell migration and metastasis116
Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis116
The many actions of insulin in skeletal muscle, the paramount tissue determining glycemia114
Serine Catabolism Feeds NADH when Respiration Is Impaired113
Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2113
Excessive exercise training causes mitochondrial functional impairment and decreases glucose tolerance in healthy volunteers112
SARS-CoV-2 infection induces beta cell transdifferentiation112
Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis109
Metformin Is Associated with Higher Incidence of Acidosis, but Not Mortality, in Individuals with COVID-19 and Pre-existing Type 2 Diabetes108
Immunometabolism in the Single-Cell Era107
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context106
Pseudomonas aeruginosa Utilizes Host-Derived Itaconate to Redirect Its Metabolism to Promote Biofilm Formation105
Insulin Treatment Is Associated with Increased Mortality in Patients with COVID-19 and Type 2 Diabetes103
Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function102
Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process102
The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson’s disease102
Mitochondrial signal transduction102
Gut-liver axis: Pathophysiological concepts and clinical implications101
Hypothalamic detection of macronutrients via multiple gut-brain pathways99
Sphingolipids in metabolic disease: The good, the bad, and the unknown99
Evolving concepts in NAD+ metabolism99
Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier99
Current Concepts, Opportunities, and Challenges of Gut Microbiome-Based Personalized Medicine in Nonalcoholic Fatty Liver Disease98
Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa198
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages98
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