Cell Metabolism

(The H4-Index of Cell Metabolism is 95. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes1107
The Metabolic Underpinnings of Ferroptosis586
Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis460
The hallmarks of cancer metabolism: Still emerging386
Benefits of Metformin in Attenuating the Hallmarks of Aging379
In-Hospital Use of Statins Is Associated with a Reduced Risk of Mortality among Individuals with COVID-19375
Omics-Driven Systems Interrogation of Metabolic Dysregulation in COVID-19 Pathogenesis374
CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability344
Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation320
Mitochondrial Metabolism as a Target for Cancer Therapy318
The Role of HIF in Immunity and Inflammation305
Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells285
The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation284
Effects of 4- and 6-h Time-Restricted Feeding on Weight and Cardiometabolic Health: A Randomized Controlled Trial in Adults with Obesity277
Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity269
Exosomes as mediators of intercellular crosstalk in metabolism256
Amino Assets: How Amino Acids Support Immunity252
Defined p16High Senescent Cell Types Are Indispensable for Mouse Healthspan229
The Gut Microbiota in Prediabetes and Diabetes: A Population-Based Cross-Sectional Study229
Endothelial Lactate Controls Muscle Regeneration from Ischemia by Inducing M2-like Macrophage Polarization221
SARS-CoV-2 infects human pancreatic β cells and elicits β cell impairment219
Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets210
Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice199
Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming198
SCENITH: A Flow Cytometry-Based Method to Functionally Profile Energy Metabolism with Single-Cell Resolution194
SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition192
Why does obesity cause diabetes?189
Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects188
The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine182
Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism182
Human Brown Adipocyte Thermogenesis Is Driven by β2-AR Stimulation180
Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes177
Diabetes, obesity, metabolism, and SARS-CoV-2 infection: the end of the beginning176
Microbiota-derived acetate enables the metabolic fitness of the brain innate immune system during health and disease175
The Power of Plasticity—Metabolic Regulation of Hepatic Stellate Cells172
Changing global epidemiology of liver cancer from 2010 to 2019: NASH is the fastest growing cause of liver cancer167
FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption166
Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes164
Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis164
Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress161
Plasticity of Epididymal Adipose Tissue in Response to Diet-Induced Obesity at Single-Nucleus Resolution159
Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity157
Gut-Resident Lactobacilli Activate Hepatic Nrf2 and Protect Against Oxidative Liver Injury157
Positive feedback regulation of microglial glucose metabolism by histone H4 lysine 12 lactylation in Alzheimer’s disease155
The Gut Microbiota at the Service of Immunometabolism153
Quantitative Fluxomics of Circulating Metabolites150
A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis149
Non-canonical Glutamate-Cysteine Ligase Activity Protects against Ferroptosis146
Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy143
Astrocyte-neuron metabolic cooperation shapes brain activity139
Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance137
MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice136
NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion135
The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure133
SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells132
The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling129
Expression of SARS-CoV-2 Entry Factors in the Pancreas of Normal Organ Donors and Individuals with COVID-19128
Mechanoresponsive metabolism in cancer cell migration and metastasis125
Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2123
The many actions of insulin in skeletal muscle, the paramount tissue determining glycemia123
Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy122
Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth122
A High-Density Human Mitochondrial Proximity Interaction Network121
Gut-liver axis: Pathophysiological concepts and clinical implications120
Mitochondrial signal transduction120
Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis118
Immunometabolism in the Single-Cell Era117
Serine Catabolism Feeds NADH when Respiration Is Impaired117
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context116
SARS-CoV-2 infection induces beta cell transdifferentiation116
The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson’s disease115
Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis114
Excessive exercise training causes mitochondrial functional impairment and decreases glucose tolerance in healthy volunteers114
Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function110
Evolving concepts in NAD+ metabolism109
Sphingolipids in metabolic disease: The good, the bad, and the unknown109
Pseudomonas aeruginosa Utilizes Host-Derived Itaconate to Redirect Its Metabolism to Promote Biofilm Formation109
Metformin Is Associated with Higher Incidence of Acidosis, but Not Mortality, in Individuals with COVID-19 and Pre-existing Type 2 Diabetes109
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages109
High-fiber diet mitigates maternal obesity-induced cognitive and social dysfunction in the offspring via gut-brain axis108
The global burden of metabolic disease: Data from 2000 to 2019107
Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process107
Insulin Treatment Is Associated with Increased Mortality in Patients with COVID-19 and Type 2 Diabetes105
Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment104
Molecular aspects of fructose metabolism and metabolic disease103
The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer103
Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1102
Efferocytosis induces macrophage proliferation to help resolve tissue injury101
KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease101
Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage101
Hypothalamic detection of macronutrients via multiple gut-brain pathways100
Current Concepts, Opportunities, and Challenges of Gut Microbiome-Based Personalized Medicine in Nonalcoholic Fatty Liver Disease99
Metabolic orchestration of the wound healing response98
Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy96
Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain95