Physiology

Article	Citations
Pathophysiology of COVID-19: Mechanisms Underlying Disease Severity and Progression	144
The SLC25 Carrier Family: Important Transport Proteins in Mitochondrial Physiology and Pathology	85
Force Steadiness: From Motor Units to Voluntary Actions	71
Gut Microbial Metabolites and Blood Pressure Regulation: Focus on SCFAs and TMAO	44
Physiological Mechanisms of Acute Upper Thermal Tolerance in Fish	36
Bile Acids, Their Receptors, and the Gut Microbiota	31
Polyamines in Gut Epithelial Renewal and Barrier Function	31
Adiponectin Synthesis, Secretion and Extravasation from Circulation to Interstitial Space	30
The Pathophysiology of Rett Syndrome With a Focus on Breathing Dysfunctions	29
Intratumoral Hypoxia and Mechanisms of Immune Evasion Mediated by Hypoxia-Inducible Factors	26
High-Altitude Erythrocytosis: Mechanisms of Adaptive and Maladaptive Responses	23
Vascular Endothelial Protein Tyrosine Phosphatase Regulates Endothelial Function	22
Gut Microbiota in Liver Disease: What Do We Know and What Do We Not Know?	22
Time of Day and Muscle Strength: A Circadian Output?	21
Cellular Pathways Promoting Pulmonary Vascular Remodeling by Hypoxia	21
Multi-Level Regulation of Opioid-Induced Respiratory Depression	21
Mechanisms of Lung Injury Induced by SARS-CoV-2 Infection	20
Is It Good to Have a Stiff Aorta with Aging? Causes and Consequences	20
From “Hunger Hormone” to “It’s Complicated”: Ghrelin Beyond Feeding Control	20
Immune Response to the Enteric ParasiteEntamoeba histolytica	20
What Can an Organ-on-a-Chip Teach Us About Human Lung Pathophysiology?	18
Physiology of Glymphatic Solute Transport and Waste Clearance from the Brain	17
Precision Nutrition: Recent Advances in Obesity	17
Physiological Impact of Hypothermia: The Good, the Bad, and the Ugly	16
COVID-19 and Inborn Errors of Immunity	16

Optogenetics: The Art of Illuminating Complex Signaling Pathways	15
Insulin, Muscle Glucose Uptake, and Hexokinase: Revisiting the Road Not Taken	15
Surviving in a Frozen Forest: the Physiology of Eastern Spruce Budworm Overwintering	14
Carotid Body Inflammation: Role in Hypoxia and in the Anti-inflammatory Reflex	14
More than Breathing Air: Evolutionary Drivers and Physiological Implications of an Amphibious Lifestyle in Fishes	13
Exercise-Pharmacology Interactions: Metformin, Statins, and Healthspan	13
Ion Transporter Gene Families as Physiological Targets of Natural Selection During Salinity Transitions in a Copepod	12
Physics and Physiology of Cell Spreading in Two and Three Dimensions	12
Deglutition and the Regulation of the Swallow Motor Pattern	12
Halogen-Induced Chemical Injury to the Mammalian Cardiopulmonary Systems	12
NAFLD: An Emerging Causal Factor for Cardiovascular Disease	11
Multiple Facets and Roles of Na+-K+-Cl−Cotransport: Mechanisms and Therapeutic Implications	11
Precision Medicine Approaches to Mental Health Care	11
Angiotensin Receptor Blockers Are Not Just for Hypertension Anymore	11
Phenotypic Frailty Assessment in Mice: Development, Discoveries, and Experimental Considerations	11
Mitochondrial Metabolism in Hibernation: Regulation and Implications	11
Air Pollution-Induced Autonomic Modulation	11
Novel Protein Therapeutics Created Using the Elastin-Like Polypeptide Platform	11
Uterine Fibroids: Hiding in Plain Sight	11
CatSper Calcium Channels: 20 Years On	10
Cryptochromes in Mammals and Birds: Clock or Magnetic Compass?	10
Interplay of the Circadian Clock and Endothelin System	10
Cannabinoid Receptors in Metabolic Regulation and Diabetes	10
Essential Role of Hemoglobin βCys93 in Cardiovascular Physiology	10
Sympathetic Innervation of White Adipose Tissue: to Beige or Not to Beige?	10
The Opto-Respiratory Compromise: Balancing Oxygen Supply and Light Transmittance in the Retina	9
Cold Exposure and the Metabolism of Mice, Men, and Other Wonderful Creatures	9
Myosin Heavy Chain as a Novel Key Modulator of Striated Muscle Resting State	9
The Mechanobiology of Vascular Remodeling in the Aging Lung	9
Promoting Nerve Regeneration: Electrical Stimulation, Gene Therapy, and Beyond	9
Kv1.3 K+Channel Physiology Assessed by Genetic and Pharmacological Modulation	9
Nondipping Blood Pressure: Predictive or Reactive Failure of Renal Sodium Handling?	8
Fetal Growth Restriction and Asthma: Is the Damage Done?	8
Remote Work During the COVID-19 Pandemic: Making the Best of It	8
The Stress of Lung Aging: Endoplasmic Reticulum and Senescence Tête-à-Tête	7
Biological Significance of the Coupling Delay in Synchronized Oscillations	7
The Guts of the Opioid Crisis	7
Minimally Invasive Ways of Determining Circadian Rhythms in Humans	7
Endothelium-Derived Dopamine and 6-Nitrodopamine in the Cardiovascular System	7
Pathophysiology of Hemorrhage as It Relates to the Warfighter	7
Pulsatile Basal Insulin Secretion Is Driven by Glycolytic Oscillations	6
Kv Channel Ancillary Subunits: Where Do We Go from Here?	6
Effects of Developmental Hypoxia on the Vertebrate Cardiovascular System	6
Systemic Reprogramming of Endothelial Cell Signaling in Metastasis and Cachexia	6
Noncytotoxic Roles of Granzymes in Health and Disease	6
Staying Hydrated in Seawater	5
What Evolutionary Evidence Implies About the Identity of the Mechanoelectrical Couplers in Vascular Smooth Muscle Cells	5
Role of mTOR Signaling for Tubular Function and Disease	5
Therapeutic Targeting of Hypoxia-A2-Adenosinergic Pathway in COVID-19 Patients	5
Recent Advances in Senolysis for Age-Related Diseases	5

Advanced Modeling of Peripheral Neuro-Effector Communication and -Plasticity	5
How and Why Does Metabolism Scale with Body Mass?	4
Sex based differences in muscle regeneration	4
Pharmacological Advances in Incretin-Based Polyagonism: What We Know and What We Don’t	4
Getting Fit to Counteract Cognitive Aging: Evidence and Future Directions	4
Prefrontal Cortex Metabolome Is Modified by Opioids, Anesthesia, and Sleep	4
Membrane Dynamics and Cation Handling in Ferroptosis	4
Circulating Cell-Free Mitochondrial DNA in Pregnancy	4
COVID-19 in Early Life: Infants and Children Are Affected Too	4
Microglia in Central Control of Metabolism	3
Targeting Parasympathetic Activity to Improve Autonomic Tone and Clinical Outcomes	3
Physiological responses of adults with coronary artery disease during extreme heat exposure	3
Physiological Needs: Sensations and Predictions in the Insular Cortex	3
Bifidobacterium bifidum prevents the IL-1B induced increase in intestinal permeability by a novel mechanism: TLR-2 dependent activation of PPAR-gamma and inhibition of NF-kB signaling pathway	3
Signaling through Free Fatty Acid Receptor 4 Attenuates Cardiometabolic Disease	3
Oral Supplementation with the Short-Chain Fatty Acid Acetate Ameliorates Age-Related Aortic Stiffening in Mice	3
Pathophysiological Roles of the cGAS-STING Inflammatory Pathway	3
All Light, Everywhere? Photoreceptors at Nonconventional Sites	3
Organelle Communication: Joined in Sickness and in Health	3
Surviving in an Acidifying Ocean: Acid-Base Physiology and Energetics of the Sea Urchin Larva	3
Circadian Rhythm Regulation by Pacemaker Neuron Chloride Oscillation in Flies	2
The nigro-vagal modulation of the proximal colon is compromised in a model of environmental Parkinson's Disease	2
RANKL and RANK in Cancer Therapy	2
Preimmune Recognition and Response to Microbial Metabolites	2
Complementing Cell Taxonomies with a Multicellular Analysis of Tissues	2
Physiological Functions of the Ubiquitin Ligases Nedd4-1 and Nedd4-2	2
CysLT1R is essential for optimal TLR4 responses and associated macrophage polarization and sepsis in response to LPS	2
Kidney Development: Recent Insights from Technological Advances	2
Tracers and Imaging of Fatty Acid and Energy Metabolism of Human Adipose Tissues	2
Looking Forward to a Bright Future at APS	2
The Emerging Concept of Transportome: State of the Art	2
Synergism Between Hypothalamic Astrocytes and Neurons in Metabolic Control	2
Inflammatory Mechanisms in Heart Failure with Preserved Ejection Fraction	2
Immune Sexual Dimorphism: Connecting the Dots	2
From Beats to Metabolism: the Heart at the Core of Interorgan Metabolic Cross Talk	2
Tissue Specificity of DNA Damage and Repair	2
A Year of Challenge and Change	2
The Elusive Hypertrophy of the Python Heart	2
Targeting adrenergic receptors to activate brown fat without cardiovascular effects	2
Glucocorticoid Receptor-beta (GRb) is a driver of adiposity via PPARgamma in adipose tissue: Lessons learned from the first CRISPR GRb KO animals	2
Physiology in Perspective: A Key Role of Physiology in Understanding COVID-19	2
4-octyl itaconate ameliorate cognitive impairment in 3xTg mouse model of Alzheimer's Disease	1
A reduction in Homeodomain Interacting Protein Kinase-2 in lung fibroblasts ameliorates lung fibrosis	1
Adhering to occupational heat stress recommendations attenuates kidney injury risk	1
Xanthine oxidase mediates stress-induced Alzheimer's Disease progression in triple transgenic mice	1
Physiological Societies Across the Globe Unite in an Effort to Handle the COVID-19 Pandemic	1
Pulmonary Vascular Dysfunctions in Cystic Fibrosis	1
Brief Smell Identification Test-1, An odor impairment Test in Patients of Depression	1
Erythropoiesis-related RNAs biomarkers are sensitive and specific to low-dose erythropoietin treatment at sea level and altitude	1
Logic of the Temporal Compartmentalization of the Hepatic Metabolic Cycle	1
Acute and reversible modulation of kidney proximal tubule endocytic capacity by fluid shear stress	1
The role of Cola nitida on gastric acid secretion and its mechanism of action in male Wistar rats	1
Bacillus subtilis 67989 improves endothelial-mediated dilation in male mice fed a western diet	1
Premenopausal women with PTSD display blunted vagal control of the heart and elevated central hemodynamics	1
A Population Health Approach to Promote Significant Learning in an Undergraduate Pathophysiology Course	1
Senolytics reduce endothelial cell DNA damage and telomere dysfunction in old age	1
Emerging Pathophysiological Roles of Ketone Bodies	1
Homocysteine-induced Barrier Dysfunction and Hyperpermeability in the Blood-Brain and Blood-Retinal Barrier: Role of NLRP3 Inflammasome Pathway	1
The Effects of Dietary Salt on Blood Pressure Variability, Cerebral Perfusion and Cognitive Function in Young-Adult Male Rats	1
The Gut Microbiota and Metabolome and Brown Adipose Tissue Regulate the Enhanced Exercise Capacity in Mice with Disruption of the Regulator of G protein Signaling 14 (RGS14)	1
Dietary intake of macro and micronutrients correspond with sleep behaviors in collegiate female soccer players	1
Promotion of hair growth by Lactobacillus and fermented traditional Korean berry in C57BL/6 mice	1
Bifidobacterium bifidum causes an enhancement of the intestinal epithelial tight junction barrier is mediated by TLR-2 dependent increases of Toll-interacting protein (TOLLIP) expression in a MYD88 in	1
Burning Question: How Does Our Brain Process Positive and Negative Cues Associated with Thermosensation?	1
Impact of total parenteral nutrition and antibiotics on hepatic and intestinal homeostasis in pediatric murine model	1
Cell Membrane Tension Gradients, Membrane Flows, and Cellular Processes	1
25-Hydroxycholesterol reduces aortic cellular senescence and stiffness in old mice	1
The role of RPTPz in neuronal intracellular pH homeostasis and in crosstalk to adjacent astrocytes	1
Lysine acetylation regulates mitochondrial pyruvate carrier activity and cardiac pyruvate oxidation	1
Physiology in Perspective: Eat, Sleep, Survive—Natural Cycle of Life	1
An animal physiology Pressbook (OER) creation process, a synergistic collaboration with undergraduates and faculty	1
Tau Hyperphosphorylation in Brain Microvasculature: Relevance to Vascular Cognitive Impairment & Dementia (VCID)	1
Electrophysiological characteristics of Panx1 channel and its purinergic regulation by P2X7 receptor	1
Regulatory Effect of L-Cysteine on Testosterone Biosynthesis Genes in Leydig Cells and THP-1 Monocytes	1
Perivascular adipose and perivascular nerve dysfunction in inflammatory bowel disease is reversed after macrophage depletion	1
Elucidating the role of Acinetobacter calcoaceticus in promoting intestinal inflammation	1
Neonatal Alveolar Type 1 Cells Produce a Pro-inflammatory Response to LPS and TNF-alpha	1
Two distinct calcium signaling behaviors are present in interstitial cells of Cajal of the gastroesophageal junction	1
The impact of skipping a meal on perceived stress and mental distress	1
Physiological effects of Plaat1 deficiency in mice	1

Dendritic cell-specific SMAD3, downstream of JAK2, contributes to inflammation and salt-sensitivity of blood pressure in humans and mice	1
Electronic cigarettes exposures modulate Heart Rate and Heart Rate Variability	1
Unraveling the role of estrogen signaling in the breast cancer-bone connection	1
Salt-dependent Role of Human Gut Commensal Coprococcus comes in Blood Pressure and Inflammation	1
MMP-13 Regulates Matrix Binding and Internalization of NG2/CSGP4 in Mandibular Fibrochondrocytes	1
Early life stress in mice leads to impaired colonic corticosterone production and prolonged inflammation following induction of colitis	1
Adiponectin receptor activation with AdipoRon prevents Truvada-induced microvascular oxidative stress and dysfunction in mice	1
Increased asprosin in epididymal adipose tissue as a potential contributor to impaired vascular function in obese mice.	1
Fibroadipogenic progenitor-derived Gdf10 regulates neuromuscular junction and fat content in tongue muscles	1
Mixed Matrix Thermoset Casting with Thermoplastic Fused Filament Fabrication 3D Printing	1
Physiology in Perspective: The New Normal—Life in a Pandemic	1
Genetic inhibition of KV7/M-channels increases the excitability of bronchopulmonary vagal nociceptive nerves	1
Role of the Circadian Clock System in Trans-sulfuration Pathway and Tissue Remodeling	1
Hemodynamic predictors for the onset of ischemic stroke due to carotid artery stenosis using a computational fluid dynamics analysis	1
Appetite control and feed intake- Can AgRP serve as a biomarker for appetite in the teleost Atlantic salmon, Salmo salar?	1
Cardiorespiratory Capacity and Body Composition are Improved with Concomitant Moderate Intensity or High-intensity Interval Training During Doxorubicin Treatment	1
Optogenetic therapy on cardiac vagal dysfunction-related ventricular arrhythmia in type 2 diabetes	1
Altered colonocyte differentiation may lead to decreased electrolyte and fluid absorption in the ileocolon of IBD patients by affecting the expression pattern of the responsible ion transporters	1
Mitochondria and renal microvascular dysfunction following ischemia-reperfusion in rats	1
Nutrition as Fuel for Human Spaceflight	1
Effect of Sex on Sympatho-inhibitors and Non-inhibitor Phenotypes during Acute Hyperoxia	1
Selective Breeding for High Intrinsic Exercise Capacity Slows Pan-Tissue Epigenetic Aging in Rats	1
Pathophysiology of Acute Kidney Frailty	1
IUPS: Physiology on a Global Scale	1
Effects of an exoskeleton-assisted walking program on bone strength in wheelchair individuals with spinal cord injury: A preliminary study using imaging and serum biomarkers	1
Identification of HMOX2 promoter variants linked to adaptation in Tibetans	1
Mosaic Loss of Y Chromosome in White Blood Cells: Its Impact on Men’s Health	1
Sex differences in swallowing response to Gaussian stochastic surface electrical stimulation	1
Anticholinesterase and Antioxidant Potential of Aqueous Leave Extract of Phyllantus Amarus in Aluminium Chloride-Induced Alzheimer's Disease in Drosophila Melanogaster	1
TRPV4 functional status in cystic cells regulates cystogenesis in autosomal recessive polycystic kidney disease (ARPKD) during variations in dietary potassium	1
Mechanisms of Pathogen and Pesticide Resistance in Honey Bees	1
The short-chain fatty acid acetate improves age-associated vascular endothelial dysfunction	1
OMICmAge: An integrative multi-omics approach to quantify biological age with electronic medical records	1
Targeting LRP1 in a rodent cervical injury model to promote functional recovery	0
Assessment of Functional Characteristics of Small Arterioles and Capillaries Using an Intact Dura Mater Preparation	0
Improving White Blood Cell Morphology Education Through Standardized Questions	0
Mild hypoxia as therapy for post-ischemic mitochondrial injury	0
Enteral protease inhibition mitigates impaired Windkessel function in experimental trauma/hemorrhagic shock	0
Role of preeclampsia on insulin-induced vasorelaxation	0
In utero Morphine Exposure Increases Blood Pressure in Association with Increased Markers of Sympathetic Activation in the Adult Offspring	0
Endothelial expression of iron transporters is dependent on contact with smooth muscle	0
Assessment of Mitochondrial Function and Vascular Permeability in Lungs of Rats Susceptible to Hyperoxia-induced Acute Respiratory Distress Syndrome (ARDS)	0
Ovarian-derived sex hormones do not mediate the sex-specific mechanism of hypertension in obese mice	0
Succinate dehydrogenase inhibition decreases mitochondrial respiratory capacity in human airway smooth muscle cells	0
Inflammation modulates the activation of autophagy in C2C12 myotubes	0
G Protein-coupled Estrogen Receptor 1 Signaling Downregulates Epithelial Na Channel Activity in the Collecting Duct	0
Mediators of steatosis in HepG2 cells	0
Caloric Restriction and Cardiovascular Health: the Good, the Bad, and the Renin-Angiotensin System	0
Airway luminal area in long COVID patients compared to acute COVID-19 patients	0
AKAP150 and Caveolin 1 underlie the formation of distinct TRPV4 signaling microdomains in vascular smooth muscle cells	0
Glucocorticoid excess and insulin resistance in aged spontaneously hypertensive rats/stroke-prone	0
Centrally derived gasotransmitter modulation of hypoglossal motoneuron activity	0
The effect of Akt-induced skeletal muscle hypertrophy on the UBR family of E3 ubiquitin ligases	0
Reactive hyperemia acutely decreases peripheral arterial stiffness	0
Human skeletal muscle possesses an epigenetic memory of high intensity interval training affecting mitochondrial function	0
The influence of early menopause on the hemodynamic responses to isometric exercise	0
The pedunculopontine tegmental nucleus is not important for breathing impairments observed in a Parkinson's disease model	0
Biological sex influences aortic hemodynamic responses to maximal exercise in healthy older adults	0
Bronchial thermoplasty attenuates bronchodilator responsiveness	0
Discovering mechanisms of altered kidney development using snRNA-seq in young HSRA rats, a model of low nephron number associated with CKD	0
Gastric Bypass reprograms hepatic clock machinery and improves glucose flux independent of weight	0
Sorbs2 is required for VSMC phenotype plasticity	0
Swallowing disrupts tongue-jaw coordination during chewing in a rat model of Parkinson's disease	0
Impact of aging on the response to mechanical ventilation in mice	0
Thyroid hormone maintains cardiac dyadic structures by regulating junctophilin-2 localization to ryanodine clusters	0
Greater renal interstitial expansion and inflammation in older male versus older female rats following a four-day simulated heatwave	0
Dietary fructose and sodium are associated with increased systolic and diastolic blood pressure in young black and white adults: the CARDIA study	0
Chronic Intermittent Hypoxia Facilitates Action Potential Firing in PVN-projecting MnPO Neurons	0
Renal denervation modulates neurohormonal activity and inflammation in heart failure with preserved ejection fraction	0
Estrogen-independent regulation of myocardial autophagy by the G protein-coupled estrogen receptor 1	0
A novel RSK3/mAKAPß signalosome-focused gene therapy inhibits developing heart failure in aortic-banded, Western diet-fed female Ossabaw swine	0
Loss of tissue inhibitor of proteinase 3 (TIMP3), but not TIMP4, worsens abdominal and thoracic aortic aneurysm	0
Chronic intermittent hypoxia induces remodeling of sympathetic innervation in mouse heart (atria and ventricles)	0
Site-specific activity of mTORC2 in regulating renal K+ secretion to maintain ion homeostasis	0
The urothelium drives changes to urinary bladder smooth muscle contractility that mimic neurogenic inflammatory signaling	0
Compliance and Elasticity in Medical Physiology: Confusion and Clarification	0
Exertional heart stroke causes long-term obesity and cardiac hypertrophy in mice	0
TNF-alpha stimulated immune response: are there sex differences?	0
Topographical Distribution and Morphology of Calcitonin Gene-Related Peptide (CGRP) Nociceptive Afferent Axons in the Flat-Mounts of the Whole Stomach in Male and Female Mice: Tracing, Digitization, a	0
Pancreatic islet cell reprogramming into insulin producers: a multi-omics approach	0
T-cell mitochondria exhibit a functional decline with obesity that is aggravated with weight loss	0
Scleraxis Alters Arterial Smooth Muscle Phenotypic Switching and Exacerbates Arterial Stiffness	0
Drosophila Clc-c as a model of human CLC-5 and Dent Disease type 1	0
Sex-specific differences in arterial stiffness and endothelial function in untreated hyperlipidemia	0
Prenatal Dexamethasone Programs Female-Biased Autonomic Dysregulation	0
T cell pro-inflammatory cytokine production in young adults with major depressive disorder	0
The Proliferative and Functional Roles of CEBP/A in Ins-1 832/13 Cells and Primary Rat Islets	0
[18F-FDG] PET/CT monitoring of tissue-specific changes in cancer patients at risk for cachexia	0
Nrf2-Keap1 in Cardiovascular Disease: Which is the Cart and Which the Horse?	0
Impact of high fat diet and krill oil supplementation on spatial memory, microglia migration and neurogenesis in aged rats	0
Bifidobacterium supplementation attenuates hypercholesterolemia induced gut-brain-testis dysfunction in a rat model	0
Plasma exosome derived MiR221 as a driver of long term hypoxia induced aberrations in pulmonary arterial phenotype in fetal sheep	0
Direct measurement of human skeletal muscle specific tension and fiber length	0
LIM kinase inhibition reduces endothelial cell cortical stiffness in diabetic arteries	0
Redistribution of blood flow during exercise is impaired in heart failure with preserved ejection fraction	0