Physiology

Article	Citations
Force Steadiness: From Motor Units to Voluntary Actions	83
Physiological Mechanisms of Acute Upper Thermal Tolerance in Fish	49
Bile Acids, Their Receptors, and the Gut Microbiota	33
Adiponectin Synthesis, Secretion and Extravasation from Circulation to Interstitial Space	31
The Pathophysiology of Rett Syndrome With a Focus on Breathing Dysfunctions	30
Intratumoral Hypoxia and Mechanisms of Immune Evasion Mediated by Hypoxia-Inducible Factors	28
Time of Day and Muscle Strength: A Circadian Output?	26
High-Altitude Erythrocytosis: Mechanisms of Adaptive and Maladaptive Responses	25
Is It Good to Have a Stiff Aorta with Aging? Causes and Consequences	24
What Can an Organ-on-a-Chip Teach Us About Human Lung Pathophysiology?	24
Multi-Level Regulation of Opioid-Induced Respiratory Depression	23
Vascular Endothelial Protein Tyrosine Phosphatase Regulates Endothelial Function	23
Precision Nutrition: Recent Advances in Obesity	22
From “Hunger Hormone” to “It’s Complicated”: Ghrelin Beyond Feeding Control	22
Mechanisms of Lung Injury Induced by SARS-CoV-2 Infection	20
Physiology of Glymphatic Solute Transport and Waste Clearance from the Brain	18
COVID-19 and Inborn Errors of Immunity	17
Physiological Impact of Hypothermia: The Good, the Bad, and the Ugly	17
Insulin, Muscle Glucose Uptake, and Hexokinase: Revisiting the Road Not Taken	16
Optogenetics: The Art of Illuminating Complex Signaling Pathways	16
Surviving in a Frozen Forest: the Physiology of Eastern Spruce Budworm Overwintering	15
Carotid Body Inflammation: Role in Hypoxia and in the Anti-inflammatory Reflex	15
Physics and Physiology of Cell Spreading in Two and Three Dimensions	14
NAFLD: An Emerging Causal Factor for Cardiovascular Disease	13
Uterine Fibroids: Hiding in Plain Sight	13

Deglutition and the Regulation of the Swallow Motor Pattern	13
Phenotypic Frailty Assessment in Mice: Development, Discoveries, and Experimental Considerations	13
More than Breathing Air: Evolutionary Drivers and Physiological Implications of an Amphibious Lifestyle in Fishes	13
Promoting Nerve Regeneration: Electrical Stimulation, Gene Therapy, and Beyond	12
Angiotensin Receptor Blockers Are Not Just for Hypertension Anymore	12
Cryptochromes in Mammals and Birds: Clock or Magnetic Compass?	12
Halogen-Induced Chemical Injury to the Mammalian Cardiopulmonary Systems	12
Precision Medicine Approaches to Mental Health Care	12
Ion Transporter Gene Families as Physiological Targets of Natural Selection During Salinity Transitions in a Copepod	12
Interplay of the Circadian Clock and Endothelin System	11
Cannabinoid Receptors in Metabolic Regulation and Diabetes	11
Myosin Heavy Chain as a Novel Key Modulator of Striated Muscle Resting State	11
CatSper Calcium Channels: 20 Years On	11
Novel Protein Therapeutics Created Using the Elastin-Like Polypeptide Platform	11
Air Pollution-Induced Autonomic Modulation	11
Multiple Facets and Roles of Na+-K+-Cl−Cotransport: Mechanisms and Therapeutic Implications	11
Cold Exposure and the Metabolism of Mice, Men, and Other Wonderful Creatures	10
Mitochondrial Metabolism in Hibernation: Regulation and Implications	10
Sympathetic Innervation of White Adipose Tissue: to Beige or Not to Beige?	10
Kv1.3 K+Channel Physiology Assessed by Genetic and Pharmacological Modulation	10
Fetal Growth Restriction and Asthma: Is the Damage Done?	9
The Opto-Respiratory Compromise: Balancing Oxygen Supply and Light Transmittance in the Retina	9
The Mechanobiology of Vascular Remodeling in the Aging Lung	9
Effects of Developmental Hypoxia on the Vertebrate Cardiovascular System	9
Remote Work During the COVID-19 Pandemic: Making the Best of It	9
Nondipping Blood Pressure: Predictive or Reactive Failure of Renal Sodium Handling?	8
The Guts of the Opioid Crisis	7
Noncytotoxic Roles of Granzymes in Health and Disease	7
Kv Channel Ancillary Subunits: Where Do We Go from Here?	7
What Evolutionary Evidence Implies About the Identity of the Mechanoelectrical Couplers in Vascular Smooth Muscle Cells	7
Biological Significance of the Coupling Delay in Synchronized Oscillations	7
Inflammatory Mechanisms in Heart Failure with Preserved Ejection Fraction	7
Endothelium-Derived Dopamine and 6-Nitrodopamine in the Cardiovascular System	7
Pathophysiology of Hemorrhage as It Relates to the Warfighter	7
Minimally Invasive Ways of Determining Circadian Rhythms in Humans	7
Systemic Reprogramming of Endothelial Cell Signaling in Metastasis and Cachexia	7
Getting Fit to Counteract Cognitive Aging: Evidence and Future Directions	6
The Stress of Lung Aging: Endoplasmic Reticulum and Senescence Tête-à-Tête	6
Recent Advances in Senolysis for Age-Related Diseases	6
Circulating Cell-Free Mitochondrial DNA in Pregnancy	6
How and Why Does Metabolism Scale with Body Mass?	6
Therapeutic Targeting of Hypoxia-A2-Adenosinergic Pathway in COVID-19 Patients	6
Pulsatile Basal Insulin Secretion Is Driven by Glycolytic Oscillations	6
Role of mTOR Signaling for Tubular Function and Disease	5
Staying Hydrated in Seawater	5
Membrane Dynamics and Cation Handling in Ferroptosis	5
Tracers and Imaging of Fatty Acid and Energy Metabolism of Human Adipose Tissues	5
All Light, Everywhere? Photoreceptors at Nonconventional Sites	5
Surviving in an Acidifying Ocean: Acid-Base Physiology and Energetics of the Sea Urchin Larva	4
Sex based differences in muscle regeneration	4

COVID-19 in Early Life: Infants and Children Are Affected Too	4
Organelle Communication: Joined in Sickness and in Health	4
Targeting Parasympathetic Activity to Improve Autonomic Tone and Clinical Outcomes	4
Prefrontal Cortex Metabolome Is Modified by Opioids, Anesthesia, and Sleep	4
Pharmacological Advances in Incretin-Based Polyagonism: What We Know and What We Don’t	4
Microglia in Central Control of Metabolism	4
Immune Sexual Dimorphism: Connecting the Dots	4
Pathophysiological Roles of the cGAS-STING Inflammatory Pathway	3
Physiological responses of adults with coronary artery disease during extreme heat exposure	3
Physiological Needs: Sensations and Predictions in the Insular Cortex	3
Oral Supplementation with the Short-Chain Fatty Acid Acetate Ameliorates Age-Related Aortic Stiffening in Mice	3
Physiological Functions of the Ubiquitin Ligases Nedd4-1 and Nedd4-2	3
From Beats to Metabolism: the Heart at the Core of Interorgan Metabolic Cross Talk	3
A Year of Challenge and Change	3
Bifidobacterium bifidum prevents the IL-1B induced increase in intestinal permeability by a novel mechanism: TLR-2 dependent activation of PPAR-gamma and inhibition of NF-kB signaling pathway	3
Signaling through Free Fatty Acid Receptor 4 Attenuates Cardiometabolic Disease	3
Mitochondrial Calcium Regulation of Cardiac Metabolism in Health and Disease	3
Cell Membrane Tension Gradients, Membrane Flows, and Cellular Processes	2
A New Phase for WNK Kinase Signaling Complexes as Biomolecular Condensates	2
The nigro-vagal modulation of the proximal colon is compromised in a model of environmental Parkinson's Disease	2
Targeting adrenergic receptors to activate brown fat without cardiovascular effects	2
Looking Forward to a Bright Future at APS	2
Synergism Between Hypothalamic Astrocytes and Neurons in Metabolic Control	2
CysLT1R is essential for optimal TLR4 responses and associated macrophage polarization and sepsis in response to LPS	2
Kidney Development: Recent Insights from Technological Advances	2
IUPS: Physiology on a Global Scale	2
RANKL and RANK in Cancer Therapy	2
Complementing Cell Taxonomies with a Multicellular Analysis of Tissues	2
The Elusive Hypertrophy of the Python Heart	2
Glucocorticoid Receptor-beta (GRb) is a driver of adiposity via PPARgamma in adipose tissue: Lessons learned from the first CRISPR GRb KO animals	2
Circadian Rhythm Regulation by Pacemaker Neuron Chloride Oscillation in Flies	2
Tissue Specificity of DNA Damage and Repair	2
Hemodynamic Characteristics of Tortuous Microvessels Using High-Fidelity Red Blood Cell Resolved Simulations	2
The Emerging Concept of Transportome: State of the Art	2
Preimmune Recognition and Response to Microbial Metabolites	2
Pulmonary Vascular Dysfunctions in Cystic Fibrosis	2
Physiological Societies Across the Globe Unite in an Effort to Handle the COVID-19 Pandemic	2
Does hyperoxia stimulate breathing?	1
Appetite control and feed intake- Can AgRP serve as a biomarker for appetite in the teleost Atlantic salmon, Salmo salar?	1
Unraveling the role of estrogen signaling in the breast cancer-bone connection	1
Acute post-exercise internal carotid artery hemodynamics are intensity dependent in young adults	1
Early life stress in mice leads to impaired colonic corticosterone production and prolonged inflammation following induction of colitis	1
The Effects of Dietary Salt on Blood Pressure Variability, Cerebral Perfusion and Cognitive Function in Young-Adult Male Rats	1
Neonatal Alveolar Type 1 Cells Produce a Pro-inflammatory Response to LPS and TNF-alpha	1
Mechanisms of Pathogen and Pesticide Resistance in Honey Bees	1
Adiponectin receptor activation with AdipoRon prevents Truvada-induced microvascular oxidative stress and dysfunction in mice	1
Pathophysiology of Acute Kidney Frailty	1
Glutamine metabolism improves cardiac function after myocardial infarction independent of macrophage polarization	1
25-Hydroxycholesterol reduces aortic cellular senescence and stiffness in old mice	1
Mosaic Loss of Y Chromosome in White Blood Cells: Its Impact on Men’s Health	1
Physiology in Perspective	1
Salt-dependent Role of Human Gut Commensal Coprococcus comes in Blood Pressure and Inflammation	1
Bacillus subtilis 67989 improves endothelial-mediated dilation in male mice fed a western diet	1
Fibroadipogenic progenitor-derived Gdf10 regulates neuromuscular junction and fat content in tongue muscles	1
TRPV4 functional status in cystic cells regulates cystogenesis in autosomal recessive polycystic kidney disease (ARPKD) during variations in dietary potassium	1
Selective Breeding for High Intrinsic Exercise Capacity Slows Pan-Tissue Epigenetic Aging in Rats	1
Molecular mechanisms of the effects of mulberry (Morus Rubra) extracts on UV-radiation and oxidative stress-induced skin cell damage	1
Exercise-induced upregulation of APOE expression is attenuated by dietary supplementation with resveratrol	1
A Population Health Approach to Promote Significant Learning in an Undergraduate Pathophysiology Course	1
Neonatal gene therapy restores breathing in a rat model of Pompe disease	1
Impact of total parenteral nutrition and antibiotics on hepatic and intestinal homeostasis in pediatric murine model	1
Emodin protects lipopolysaccharide-induced myocardial injury and mitochondrial dysfunction via PI3K/AKT signaling pathway based on Network Pharmacology	1
Physical and functional interaction between NHE3 and SGLT2 in the renal proximal tubule of male and female rats	1
Elucidating the role of Acinetobacter calcoaceticus in promoting intestinal inflammation	1
Electrophysiological characteristics of Panx1 channel and its purinergic regulation by P2X7 receptor	1
Tools for studying enteroendocrine cell subtype development and physiology in zebrafish	1
Increased asprosin in epididymal adipose tissue as a potential contributor to impaired vascular function in obese mice.	1
Emerging Pathophysiological Roles of Ketone Bodies	1
Physiology in Perspective: Eat, Sleep, Survive—Natural Cycle of Life	1
Fecal Dysbiosis and Inflammation in Intestinal-Specific Cftr Knockout Mice	1
The role of RPTPz in neuronal intracellular pH homeostasis and in crosstalk to adjacent astrocytes	1
Regulatory Effect of L-Cysteine on Testosterone Biosynthesis Genes in Leydig Cells and THP-1 Monocytes	1
Brief Smell Identification Test-1, An odor impairment Test in Patients of Depression	1
Sex differences in swallowing response to Gaussian stochastic surface electrical stimulation	1
MYO5B levels are linked to microRNAs and UNC45A in colorectal cancer	1
Probiotic strains isolated from natural products alleviate gut inflammation in a human epithelial HT-29 in vitro model	1
Homocysteine-induced Barrier Dysfunction and Hyperpermeability in the Blood-Brain and Blood-Retinal Barrier: Role of NLRP3 Inflammasome Pathway	1
ECM Microenvironment in Vascular Homeostasis: New Targets for Atherosclerosis	1
Effect of Sex on Sympatho-inhibitors and Non-inhibitor Phenotypes during Acute Hyperoxia	1
Adhering to occupational heat stress recommendations attenuates kidney injury risk	1

Deletion of the Aryl Hydrocarbon Receptor in Endothelial Cells Improves Ischemic Angiogenesis in Chronic Kidney Disease	1
Senolytics reduce endothelial cell DNA damage and telomere dysfunction in old age	1
Role of glycocalyx in breast cancer cell adhesion and transmigration across an in vitro blood-brain barrier (BBB)	1
Burning Question: How Does Our Brain Process Positive and Negative Cues Associated with Thermosensation?	1
The Gut Microbiota and Metabolome and Brown Adipose Tissue Regulate the Enhanced Exercise Capacity in Mice with Disruption of the Regulator of G protein Signaling 14 (RGS14)	1
Targeting Melanocortin 4 Receptor to Treat Sleep-Disordered Breathing	1
4-octyl itaconate ameliorate cognitive impairment in 3xTg mouse model of Alzheimer's Disease	1
Hemodynamic predictors for the onset of ischemic stroke due to carotid artery stenosis using a computational fluid dynamics analysis	1
Anticholinesterase and Antioxidant Potential of Aqueous Leave Extract of Phyllantus Amarus in Aluminium Chloride-Induced Alzheimer's Disease in Drosophila Melanogaster	1
The impact of skipping a meal on perceived stress and mental distress	1
Unexpected hypertrophic, phenotypical, and oxidative metabolism transcriptional adaptations in response to resistance training following 10 days of muscle disuse	1
Cholesterol, not fat, is critical in atherogenesis induced by intermittent hypoxia and hypercapnia	1
An animal physiology Pressbook (OER) creation process, a synergistic collaboration with undergraduates and faculty	1
New Insights into IGF-1 Signaling in the Heart	1
Unraveling the Enigma of Organismal Death: Insights, Implications, and Unexplored Frontiers	1
Erythropoiesis-related RNAs biomarkers are sensitive and specific to low-dose erythropoietin treatment at sea level and altitude	1
Tau Hyperphosphorylation in Brain Microvasculature: Relevance to Vascular Cognitive Impairment & Dementia (VCID)	1
A reduction in Homeodomain Interacting Protein Kinase-2 in lung fibroblasts ameliorates lung fibrosis	1
Nutrition as Fuel for Human Spaceflight	1
The role of Cola nitida on gastric acid secretion and its mechanism of action in male Wistar rats	1
IL-1R mediated renal sensory nerve activity drives hypertension in the DOCA-Salt mouse	1
Mixed Matrix Thermoset Casting with Thermoplastic Fused Filament Fabrication 3D Printing	1
Dendritic cell-specific SMAD3, downstream of JAK2, contributes to inflammation and salt-sensitivity of blood pressure in humans and mice	1
Altered colonocyte differentiation may lead to decreased electrolyte and fluid absorption in the ileocolon of IBD patients by affecting the expression pattern of the responsible ion transporters	1
Cardiorespiratory Capacity and Body Composition are Improved with Concomitant Moderate Intensity or High-intensity Interval Training During Doxorubicin Treatment	1
Does acute heat stress alter lactation performance in postpartum mothers?	1
Optogenetic therapy on cardiac vagal dysfunction-related ventricular arrhythmia in type 2 diabetes	1
Dietary intake of macro and micronutrients correspond with sleep behaviors in collegiate female soccer players	1
Promotion of hair growth by Lactobacillus and fermented traditional Korean berry in C57BL/6 mice	1
The regulatory role of Sirtuin 6 in coronary endothelial dysfunction in HFpEF	1
Effects of an exoskeleton-assisted walking program on bone strength in wheelchair individuals with spinal cord injury: A preliminary study using imaging and serum biomarkers	1
Protective role of short chain fatty acids against Angiotensin II-induced mitochondrial dysfunction in brain endothelial cells: Potential role of Heme Oxygenase 2	1
Premenopausal women with PTSD display blunted vagal control of the heart and elevated central hemodynamics	1
Dietary pattern, body composition, metabolic markers, and skin physiology	1
Xanthine oxidase mediates stress-induced Alzheimer's Disease progression in triple transgenic mice	1
Electronic cigarettes exposures modulate Heart Rate and Heart Rate Variability	1
Predictors of Arterial Occlusion Pressure in the Lower-Body Across Commonly Used Cuff Widths	1
Deciphering the potential of a novel cytostatic autophagy modulator for the treatment of brain cancer along with reduction in brain inflammation	1
Lysine acetylation regulates mitochondrial pyruvate carrier activity and cardiac pyruvate oxidation	1
Genetic inhibition of KV7/M-channels increases the excitability of bronchopulmonary vagal nociceptive nerves	1
MMP-13 Regulates Matrix Binding and Internalization of NG2/CSGP4 in Mandibular Fibrochondrocytes	1
Two distinct calcium signaling behaviors are present in interstitial cells of Cajal of the gastroesophageal junction	1
The short-chain fatty acid acetate improves age-associated vascular endothelial dysfunction	1
Bifidobacterium bifidum causes an enhancement of the intestinal epithelial tight junction barrier is mediated by TLR-2 dependent increases of Toll-interacting protein (TOLLIP) expression in a MYD88 in	1
Physiological effects of Plaat1 deficiency in mice	1
Mitochondria and renal microvascular dysfunction following ischemia-reperfusion in rats	1
OMICmAge: An integrative multi-omics approach to quantify biological age with electronic medical records	1
Rational design and synthesis of angiotensin-converting enzyme 2 inhibitors targeting severe acute respiratory syndrome coronavirus 2	1
Nrf2-Keap1 in Cardiovascular Disease: Which Is the Cart and Which the Horse?	1
Acute and reversible modulation of kidney proximal tubule endocytic capacity by fluid shear stress	1
Perivascular adipose and perivascular nerve dysfunction in inflammatory bowel disease is reversed after macrophage depletion	1
A Novel mouse model derived from an uncharacterized MVID patient MYO5B mutation	1
Setmelanotide, a melanocortin-4-receptor agonist, increases the hypercapnic ventilatory response and relieves hypoventilation in obese mice	1
Pathophysiological role of NAMPT in endothelial function	1
Logic of the Temporal Compartmentalization of the Hepatic Metabolic Cycle	1
Acute fatigue induces paradoxical increases in velocity and power in a sex and myosin isoform dependent manner	1
Role of the Circadian Clock System in Trans-sulfuration Pathway and Tissue Remodeling	1
Identification of HMOX2 promoter variants linked to adaptation in Tibetans	1
Site-specific activity of mTORC2 in regulating renal K+ secretion to maintain ion homeostasis	0
Compliance and Elasticity in Medical Physiology: Confusion and Clarification	0
TNF-alpha stimulated immune response: are there sex differences?	0
Pancreatic islet cell reprogramming into insulin producers: a multi-omics approach	0
Scleraxis Alters Arterial Smooth Muscle Phenotypic Switching and Exacerbates Arterial Stiffness	0
Sex-specific differences in arterial stiffness and endothelial function in untreated hyperlipidemia	0
T cell pro-inflammatory cytokine production in young adults with major depressive disorder	0
[18F-FDG] PET/CT monitoring of tissue-specific changes in cancer patients at risk for cachexia	0
The Proliferative and Functional Roles of CEBP/A in Ins-1 832/13 Cells and Primary Rat Islets	0
Impact of high fat diet and krill oil supplementation on spatial memory, microglia migration and neurogenesis in aged rats	0
Caloric Restriction and Cardiovascular Health: the Good, the Bad, and the Renin-Angiotensin System	0
Bifidobacterium supplementation attenuates hypercholesterolemia induced gut-brain-testis dysfunction in a rat model	0
Direct measurement of human skeletal muscle specific tension and fiber length	0
Redistribution of blood flow during exercise is impaired in heart failure with preserved ejection fraction	0
Assessment of Functional Characteristics of Small Arterioles and Capillaries Using an Intact Dura Mater Preparation	0
Mild hypoxia as therapy for post-ischemic mitochondrial injury	0
Role of preeclampsia on insulin-induced vasorelaxation	0
Endothelial expression of iron transporters is dependent on contact with smooth muscle	0
Ovarian-derived sex hormones do not mediate the sex-specific mechanism of hypertension in obese mice	0
Inflammation modulates the activation of autophagy in C2C12 myotubes	0
Mediators of steatosis in HepG2 cells	0
G Protein-coupled Estrogen Receptor 1 Signaling Downregulates Epithelial Na Channel Activity in the Collecting Duct	0
Airway luminal area in long COVID patients compared to acute COVID-19 patients	0
Renal denervation modulates neurohormonal activity and inflammation in heart failure with preserved ejection fraction	0
AKAP150 and Caveolin 1 underlie the formation of distinct TRPV4 signaling microdomains in vascular smooth muscle cells	0
Centrally derived gasotransmitter modulation of hypoglossal motoneuron activity	0
Reactive hyperemia acutely decreases peripheral arterial stiffness	0
The influence of early menopause on the hemodynamic responses to isometric exercise	0
Biological sex influences aortic hemodynamic responses to maximal exercise in healthy older adults	0
Discovering mechanisms of altered kidney development using snRNA-seq in young HSRA rats, a model of low nephron number associated with CKD	0
Sorbs2 is required for VSMC phenotype plasticity	0
Impact of aging on the response to mechanical ventilation in mice	0
Greater renal interstitial expansion and inflammation in older male versus older female rats following a four-day simulated heatwave	0
Chronic Intermittent Hypoxia Facilitates Action Potential Firing in PVN-projecting MnPO Neurons	0
Dietary fructose and sodium are associated with increased systolic and diastolic blood pressure in young black and white adults: the CARDIA study	0
Estrogen-independent regulation of myocardial autophagy by the G protein-coupled estrogen receptor 1	0
Loss of tissue inhibitor of proteinase 3 (TIMP3), but not TIMP4, worsens abdominal and thoracic aortic aneurysm	0