RNA Biology

Article	Citations
Secondary structure of the SARS-CoV-2 5’-UTR	94
Recent advances in the regulation of plant miRNA biogenesis	64
FTO demethylates m6A modifications in HOXB13 mRNA and promotes endometrial cancer metastasis by activating the WNT signalling pathway	61
Off-target effects of RNAi correlate with the mismatch rate between dsRNA and non-target mRNA	53
Single-cell RNA-seq clustering: datasets, models, and algorithms	49
The stress specific impact of ALKBH1 on tRNA cleavage and tiRNA generation	49
3D RNA-seq: a powerful and flexible tool for rapid and accurate differential expression and alternative splicing analysis of RNA-seq data for biologists	47
Controversies around the function of LARP1	46
Computational methods for RNA modification detection from nanopore direct RNA sequencing data	45
GR-mediated FTO transactivation induces lipid accumulation in hepatocytes via demethylation of m6A on lipogenic mRNAs	45
RNA-binding proteins in neurological development and disease	41
Transfer RNAs: diversity in form and function	40
OncotRF: an online resource for exploration of tRNA-derived fragments in human cancers	39
Isolation and initial structure-functional characterization of endogenous tRNA-derived stress-induced RNAs	38
Novel insights into the emerging roles of tRNA-derived fragments in mammalian development	38
The emerging role and significance of circular RNAs in viral infections and antiviral immune responses: possible implication as theranostic agents	37
Adenosine-to-inosine RNA editing in neurological development and disease	37
Human umbilical cord mesenchymal stem cells-derived exosomal microRNA-451a represses epithelial–mesenchymal transition of hepatocellular carcinoma cells by inhibiting ADAM10	36
The diversity, plasticity, and adaptability of cap-dependent translation initiation and the associated machinery	34
Small molecule inhibitor of Igf2bp1 represses Kras and a pro-oncogenic phenotype in cancer cells	34
RNA-based therapeutics for neurological diseases	32
Cellular miR-150-5p may have a crucial role to play in the biology of SARS-CoV-2 infection by regulating nsp10 gene	32
The role of lncRNAs in innate immunity and inflammation	31
New progresses of circular RNA biology: from nuclear export to degradation	31
Linking the association between circRNAs and Alzheimer’s disease progression by multi-tissue circular RNA characterization	30

Insights into lncRNAs in Alzheimer’s disease mechanisms	30
Site-directed RNA editing: recent advances and open challenges	29
Differential roles of YTHDF1 and YTHDF3 in embryonic stem cell-derived cardiomyocyte differentiation	28
Modulation of mammalian translation by a ribosome-associated tRNA half	28
Mapping rRNA 2’-O-methylations and identification of C/D snoRNAs in Arabidopsis thaliana plants	27
LncRNAs in adaptive immunity: role in physiological and pathological conditions	26
Circular RNA circ-LDLRAD3 serves as an oncogene to promote non-small cell lung cancer progression by upregulating SLC1A5 through sponging miR-137	26
Advances in siRNA therapeutics and synergistic effect on siRNA activity using emerging dual ribose modifications	26
Long non-coding RNA NEAT1_1 ameliorates TDP-43 toxicity in in vivo models of TDP-43 proteinopathy	26
Production and purification of endogenously modified tRNA-derived small RNAs	26
MIR210HG regulates glycolysis, cell proliferation, and metastasis of pancreatic cancer cells through miR-125b-5p/HK2/PKM2 axis	24
Reprogramming of m6A epitranscriptome is crucial for shaping of transcriptome and proteome in response to hypoxia	24
Functions and mechanisms of circular RNAs in regulating stem cell differentiation	24
Role of the RNA-binding protein La in cancer pathobiology	24
The role of long non-coding RNAs in mediating chemoresistance by modulating autophagy in cancer	24
The distinct roles of zinc finger CCHC-type (ZCCHC) superfamily proteins in the regulation of RNA metabolism	23
Emerging roles of novel small non-coding regulatory RNAs in immunity and cancer	23
ncRPheno: a comprehensive database platform for identification and validation of disease related noncoding RNAs	23
Novel insights into the roles of tRNA-derived small RNAs	23
Molecular correction of Duchenne muscular dystrophy by splice modulation and gene editing	22
Molecular mechanism of microRNA-21 promoting Schwann cell proliferation and axon regeneration during injured nerve repair	22
Non-coding RNAs: the extensive and interactive regulators of the blood-brain barrier permeability	22
LncRNA MAGI2-AS3 inhibits the self-renewal of leukaemic stem cells by promoting TET2-dependent DNA demethylation of the LRIG1 promoter in acute myeloid leukaemia	21
The large repertoire of 2’-O-methylation guided by C/D snoRNAs on Trypanosoma brucei rRNA	21
Using RNA sequencing to identify a putative lncRNA-associated ceRNA network in laryngeal squamous cell carcinoma	21
Clinical advances of RNA therapeutics for treatment of neurological and neuromuscular diseases	21
Axonal mRNA translation in neurological disorders	21
Distribution, organization an evolutionary history of La and LARPs in eukaryotes	20
IGF2BP2 stabilized FBXL19-AS1 regulates the blood-tumour barrier permeability by negatively regulating ZNF765 by STAU1-mediated mRNA decay	20
miR-34 regulates larval growth and wing morphogenesis by directly modulating ecdysone signalling and cuticle protein inBombyx mori	20
Combining tRNA sequencing methods to characterize plant tRNA expression and post-transcriptional modification	20
G2-quadruplex in the 3’UTR of IE180 regulates Pseudorabies virus replication by enhancing gene expression	20
The role of OncoSnoRNAs and Ribosomal RNA 2’-O-methylation in Cancer	20
Unique features of the m6A methylome and its response to drought stress in sea buckthorn (Hippophae rhamnoides Linn.)	19
Silencing long non-coding RNA NEAT1 attenuates rheumatoid arthritis via the MAPK/ERK signalling pathway by downregulating microRNA-129 and microRNA-204	19
Splice variants of lncRNA RNA ANRIL exert opposing effects on endothelial cell activities associated with coronary artery disease	19
Introducing differential RNA-seq mapping to track the early infection phase forPseudomonasphage ɸKZ	19
mRNA m5C controls adipogenesis by promoting CDKN1A mRNA export and translation	19
Enterotoxigenic Escherichia coli infection promotes enteric defensin expression via FOXO6-METTL3-m6A-GPR161 signalling axis	19
TRA2A-induced upregulation of LINC00662 regulates blood-brain barrier permeability by affecting ELK4 mRNA stability in Alzheimer’s microenvironment	19
Innovative developments and emerging technologies in RNA therapeutics	19
Constitutive and variable 2’-O-methylation (Nm) in human ribosomal RNA	19
Demystifying mRNA vaccines: an emerging platform at the forefront of cryptic diseases	19
RNA folding and functions of RNA helicases in ribosome biogenesis	19
MHC Class III RNA Binding Proteins and Immunity	18
Small RNAs OmrA and OmrB promote class III flagellar gene expression by inhibiting the synthesis of anti-Sigma factor FlgM	18
2lpiRNApred: a two-layered integrated algorithm for identifying piRNAs and their functions based on LFE-GM feature selection	18
On the functional relevance of spatiotemporally-specific patterns of experience-dependent long noncoding RNA expression in the brain	18
NEDD4 triggers FOXA1 ubiquitination and promotes colon cancer progression under microRNA-340-5p suppression and ATF1 upregulation	18
20-Hydroxyecdysone-responsive microRNAs of insects	18

Peripheral blood microRNAs and the COVID-19 patient: methodological considerations, technical challenges and practice points	18
Identification of spliceosome components pivotal to breast cancer survival	17
Circular ANRIL isoforms switch from repressors to activators of p15/CDKN2B expression during RAF1 oncogene-induced senescence	17
Evidence for selection on SARS-CoV-2 RNA translation revealed by the evolutionary dynamics of mutations in UTRs and CDSs	17
Mechanisms of non-coding RNA-modulated alternative splicing in cancer	17
The isolated La-module of LARP1 mediates 3’ poly(A) protection and mRNA stabilization, dependent on its intrinsic PAM2 binding to PABPC1	17
Large-scale transcriptome-wide profiling of microRNAs in human placenta and maternal plasma at early to mid gestation	16
Regulation of the p53 expression profile by hnRNP K under stress conditions	16
Role of PIWI-like 4 in modulating neuronal differentiation from human embryonal carcinoma cells	16
CBRPP: a new RNA-centric method to study RNA–protein interactions	16
HSM6AP: a high-precision predictor for the HomosapiensN6-methyladenosine (m^6 A) based on multiple weights and feature stitching	16
Oxidative stress enhances the expression of 2′,3′-cyclic phosphate-containing RNAs	16
LARP1 and LARP4: up close with PABP for mRNA 3’ poly(A) protection and stabilization	15
Identification of NOVA family proteins as novel β-catenin RNA-binding proteins that promote epithelial-mesenchymal transition	15
A comprehensive coverage insurance for cells: revealing links between ribosome collisions, stress responses and mRNA surveillance	15
Emerging roles of long non-coding RNAs in the p53 network	15
The regulatory world of tRNA fragments beyond canonical tRNA biology	15
RNA 5-methylcytosine modification and its emerging role as an epitranscriptomic mark	15
Bulges control pri-miRNA processing in a position and strand-dependent manner	15
IGF2BP1 is a targetable SRC/MAPK-dependent driver of invasive growth in ovarian cancer	15
Highly dynamic transcriptional reprogramming and shorter isoform shifts under acute stresses during biological invasions	14
Long non-coding RNA HOTAIR regulates myeloid differentiation through the upregulation of p21 via miR-17-5p in acute myeloid leukaemia	14
Structural and functional insights into human tRNA guanine transglycosylase	14
The multifaceted functions of the Fat mass and Obesity-associated protein (FTO) in normal and cancer cells	14
Interrogating lncRNA functions via CRISPR/Cas systems	14
Differential transcription profiling of the phage LUZ19 infection process in different growth media	14
New substrates and determinants for tRNA recognition of RNA methyltransferase DNMT2/TRDMT1	14
LncRBase V.2: an updated resource for multispecies lncRNAs and ClinicLSNP hosting genetic variants in lncRNAs for cancer patients	14
Elucidating the cellular dynamics of the brain with single-cell RNA sequencing	14
The DExD box ATPase DDX55 is recruited to domain IV of the 28S ribosomal RNA by its C-terminal region	14
RNA transport from transcription to localized translation: a single molecule perspective	14
Dissecting protein domain variability in the core RNA interference machinery of five insect orders	14
LncRNAs in molluscan and mammalian stages of parasitic schistosomes are developmentally-regulated and coordinately expressed with protein-coding genes	14
Insights into circular RNAs: their biogenesis, detection, and emerging role in cardiovascular disease	13
The diversity of Shine-Dalgarno sequences sheds light on the evolution of translation initiation	13
The effects of RNA editing in cancer tissue at different stages in carcinogenesis	13
Discovery of new group I-D introns leads to creation of subtypes and link to an adaptive response of the mitochondrial genome in fungi	13
rG4-seeker enables high-confidence identification of novel and non-canonical rG4 motifs from rG4-seq experiments	13
Xrn1 influence on gene transcription results from the combination of general effects on elongating RNA pol II and gene-specific chromatin configuration	13
Mitochondrial noncoding RNAs: new wine in an old bottle	13
Comprehensive analysis of the pre-ribosomal RNA maturation pathway in a methanoarchaeon exposes the conserved circularization and linearization mode in archaea	13
tRNA-modifying enzyme mutations induce codon-specific mistranslation and protein aggregation in yeast	13
Utilization of microRNAs and their regulatory functions for improving biotic stress tolerance in tea plant [Camellia sinensis (L.) O. Kuntze]	13
Psychrophilic phage VSW-3 RNA polymerase reduces both terminal and full-length dsRNA byproducts in in vitro transcription	13
Alternative splicing and MicroRNA: epigenetic mystique in male reproduction	12
In silico identification of pseudo-exon activation events in personal genome and transcriptome data	12
LncRNAs as tumor cell intrinsic factors that affect cancer immunotherapy	12
Long non-coding RNA RP11-283G6.5 confines breast cancer development through modulating miR-188-3p/TMED3/Wnt/β-catenin signalling	12
Identification of alternatively spliced gene isoforms and novel noncoding RNAs by single-molecule long-read sequencing in Camellia	12
Alternative splicing diversifies the transcriptome and proteome of the rice blast fungus during host infection	12
Inhibition of CDK9 activity compromises global splicing in prostate cancer cells	12
Accurate identification of RNA D modification using multiple features	12
Stabilize and connect: the role of LARP7 in nuclear non-coding RNA metabolism	12
Comprehensive discovery of novel structured noncoding RNAs in 26 bacterial genomes	12
LncRNA CASC21 induces HGH1 to mediate colorectal cancer cell proliferation, migration, EMT and stemness	12
Gene co-expression and alternative splicing analysis of key metabolic tissues to unravel the regulatory signatures of fatty acid composition in cattle	12
Comparative analysis of circular RNA enrichment methods	12
In lysate RNA digestion provides insights into the angiogenin’s specificity towards transfer RNAs	12
RNA methylation in chloroplasts or mitochondria in plants	12
Tricks and threats of RNA viruses – towards understanding the fate of viral RNA	12
Selective packaged circular RNAs in milk extracellular vesicles during Staphylococcus aureus infection may have potential against bacterial infection	12
LARP1 isoform expression in human cancer cell lines	11
Deciphering nucleotide modification-induced structure and stability changes	11
Might exogenous circular RNAs act as protein-coding transcripts in plants?	11
Identification of RNAs bound by Hfq reveals widespread RNA partners and a sporulation regulator in the human pathogen Clostridioides difficile	11
Alu RNA and their roles in human disease states	11
Comprehensive analysis of the translatome reveals the relationship between the translational and transcriptional control in high fat diet-induced liver steatosis	11
Caenorhabditis eleganssystemic RNA interference defective protein 1 enhances RNAi efficiency in a lepidopteran insect, the fall armyworm, in a tissue-specific manner	11
SR7 – a dual-function antisense RNA from Bacillus subtilis	11
In vivo discovery of RNA proximal proteins via proximity-dependent biotinylation	11
DARS-AS1 recruits METTL3/METTL14 to bind and enhance DARS mRNA m 6 A modification and translation for cytoprotective autophagy in cervical cancer	11
Thrombosis-related circulating miR-16-5p is associated with disease severity in patients hospitalised for COVID-19	11
Human cytomegalovirus (HCMV)-encoded microRNAs: potential biomarkers and clinical applications	11
Broad-range RNA modification analysis of complex biological samples using rapid C18-UPLC-MS	11
ncRNAs and polyphenols: new therapeutic strategies for hypertension	11
The mRNA derived MalH sRNA contributes to alternative carbon source utilization by tuning maltoporin expression in E. coli	11
Ctcf haploinsufficiency mediates intron retention in a tissue-specific manner	11
Read-through circular RNAs reveal the plasticity of RNA processing mechanisms in human cells	11
Epigenomics-based identification of oestrogen-regulated long noncoding RNAs in ER+ breast cancer	11
Guanine Nucleotide-Binding Protein-Like 1 (GNL1) binds RNA G-quadruplex structures in genes associated with Parkinson’s disease	11

Rbm24 regulates inner-ear-specific alternative splicing and is essential for maintaining auditory and motor coordination	10
M6A-BiNP: predicting N6-methyladenosine sites based on bidirectional position-specific propensities of polynucleotides and pointwise joint mutual information	10
Bacterial RNA chaperones and chaperone-like riboregulators: behind the scenes of RNA-mediated regulation of cellular metabolism	10
Structure of S. pombe telomerase protein Pof8 C-terminal domain is an xRRM conserved among LARP7 proteins	10
RNA-protein coevolution study of Gemin5 uncovers the role of the PXSS motif of RBS1 domain for RNA binding	10
Bisulphite miRNA-seq reveals widespread CpG and non-CpG 5-(hydroxy)methyl-Cytosine in human microRNAs	10
NCBP3/SNHG6 inhibits GBX2 transcription in a histone modification manner to facilitate the malignant biological behaviour of glioma cells	10
SUVA: splicing site usage variation analysis from RNA-seq data reveals highly conserved complex splicing biomarkers in liver cancer	10
MicroRNA-140-3p alleviates intervertebral disc degeneration via KLF5/N-cadherin/MDM2/Slug axis	10
Upon heat stress processing of ribosomal RNA precursors into mature rRNAs is compromised after cleavage at primary P site in Arabidopsis thalian a	10
Regulation of human telomerase RNA biogenesis and localization	10
Characterization of synthetic riboswitch in cell-free protein expression systems	10
A conserved motif in human BTG1 and BTG2 proteins mediates interaction with the poly(A) binding protein PABPC1 to stimulate mRNA deadenylation	10
Accurate characterization of Escherichia coli tRNA modifications with a simple method of deep-sequencing library preparation	10
Hairpin sequence and structure is associated with features of isomiR biogenesis	10
Structural dynamics in the La-module of La-related proteins	10
Genomic amplification of long noncoding RNA HOTAIRM1 drives anaplastic thyroid cancer progression via repressing miR-144 biogenesis	10
Rpb4 and Puf3 imprint and post-transcriptionally control the stability of a common set of mRNAs in yeast	9
CITEMO XMBD : A flexible single-cell multimodal omics analysis framework to reveal the heterogeneity of immune cells	9
Genomically Hardwired Regulation of Gene Activity Orchestrates Cellular Iron Homeostasis in Arabidopsis	9
miRNA: local guardians of presynaptic function in plasticity and disease	9
Interplays of different types of epitranscriptomic mRNA modifications	9
Intron-assisted, viroid-based production of insecticidal circular double-stranded RNA in Escherichia coli	9
Nuclear SR-protein mediated mRNA quality control is continued in cytoplasmic nonsense-mediated decay	9
Hypoxia activated long non-coding RNA HABON regulates the growth and proliferation of hepatocarcinoma cells by binding to and antagonizing HIF-1 alpha	9
Maintaining mitochondrial ribosome function: The role of ribosome rescue and recycling factors	9
Regulation of mRNA stability by RBPs and noncoding RNAs contributing to the pathogenicity of Th17 cells	9
Antisense RNA asPcrL regulates expression of photosynthesis genes in Rhodobacter sphaeroides by promoting RNase III-dependent turn-over of puf mRNA	9
Comprehensive characterization of mRNAs associated with yeast cytosolic aminoacyl-tRNA synthetases	9
hnRNPH1-MTR4 complex-mediated regulation of NEAT1v2 stability is critical for IL8 expression	9
Targeted RNA sequencing enhances gene expression profiling of ultra-low input samples	9
Architectures and complex functions of tandem riboswitches	9
Subcellular relocalization and nuclear redistribution of the RNA methyltransferases TRMT1 and TRMT1L upon neuronal activation	9
Comparative CRISPR type III-based knockdown of essential genes in hyperthermophilic Sulfolobales and the evasion of lethal gene silencing	9
PresRAT: a server for identification of bacterial small-RNA sequences and their targets with probable binding region	9
Integrated multi-omics reveals common properties underlying stress granule and P-body formation	9
6S-2 RNA deletion in the undomesticated B. subtilis strain NCIB 3610 causes a biofilm derepression phenotype	9
Synergistic regulation of Rgs4 mRNA by HuR and miR-26/RISC in neurons	9
mRNAs sequestered in stress granules recover nearly completely for translation	9
sRNARFTarget: a fast machine-learning-based approach for transcriptome-wide sRNA target prediction	9
U1 snRNP telescripting: molecular mechanisms and beyond	9
Spatiotemporal expression of long noncoding RNA Moshe modulates heart cell lineage commitment	9
Ribosome profiling analysis of human skeletal muscle identifies reduced translation of mitochondrial proteins with age	9
Evolution of complexity in non-viral oligonucleotide delivery systems: from gymnotic delivery through bioconjugates to biomimetic nanoparticles	9
A genetic variant alters the secondary structure of the lncRNA H19 and is associated with dilated cardiomyopathy	9
Position of Deltaproteobacteria Cas12e nuclease cleavage sites depends on spacer length of guide RNA	9
Interplay between host non-coding RNAs and influenza viruses	9
Structural insights into dpCoA-RNA decapping by NudC	9
Synergistic roles for human U1 snRNA stem-loops in pre-mRNA splicing	9
Variations in transfer and ribosomal RNA epitranscriptomic status can adapt eukaryote translation to changing physiological and environmental conditions	8
A chromatin-associated splicing isoform of OIP5-AS1 acts in cis to regulate the OIP5 oncogene	8
LINC00857 regulated by ZNF460 enhances the expression of CLDN12 by sponging miR-150-5p and recruiting SRSF1 for alternative splicing to promote epithelial-mesenchymal transformation of pancreatic aden	8
Systematics for types and effects of RNA variations	8
Role of the 40S beak ribosomal protein eS12 in ribosome biogenesis and function inSaccharomyces cerevisiae	8
Principles and correction of 5’-splice site selection	8
Leader RNA regulates snakehead vesiculovirus replication via interacting with viral nucleoprotein	8
Comparative analysis of long noncoding RNAs in long-lived mammals provides insights into natural cancer-resistance	8
Burkitt lymphoma-related TCF3 mutations alter TCF3 alternative splicing by disrupting hnRNPH1 binding	8
Multiple dengue virus serotypes resistant transgenicAedes aegyptifitness evaluated under laboratory conditions	8
Biochemical analysis of cleavage and ligation activities of the pistol ribozyme from Paenibacillus polymyxa	8
Long non-coding RNATUG1and its molecular mechanisms in polycystic ovary syndrome	8
Alternatively spliced isoforms of AUF1 regulate a miRNA–mRNA interaction differentially through their YGG motif	8
Structural model of the M7G46 Methyltransferase TrmB in complex with tRNA	8
M6ADD: a comprehensive database of m6A modifications in diseases	8
EMP32 is required for the cis-splicing of nad7 intron 2 and seed development in maize	8
Direct RNA–RNA interaction between Neat1 and RNA targets, as a mechanism for RNAs paraspeckle retention	8
Optimal RNA binding by Egalitarian, a Dynein cargo adaptor, is critical for maintaining oocyte fate in Drosophila	8
RNA nanotechnology to build a dodecahedral genome of single-stranded RNA virus	8
Synthetase of the methyl donor S-adenosylmethionine from nitrogen-fixing α-rhizobia can bind functionally diverse RNA species	8
Optimization and characterization of position-selective labelling of RNA (PLOR) for diverse RNA and DNA sequences	8
Localization of RNAs in the nucleus: cis- and trans- regulation	8
The large family of PC4-like domains – similar folds and functions throughout all kingdoms of life	8
Diversification of piRNAs expressed in PGCs and somatic cells during embryonic gonadal development	8
ncRNA BC1 influences translation in the oocyte	8
microRNA-21: a key modulator in oncogenic viral infections	8
piRNAQuest V.2: an updated resource for searching through the piRNAome of multiple species	8
The zinc finger domains in U2AF26 and U2AF35 have diverse functionalities including a role in controlling translation	8
Identification of host factors binding to dengue and Zika virus subgenomic RNA by efficient yeast three-hybrid screens of the human ORFeome	7
F/YGG-motif is an intrinsically disordered nucleic-acid binding motif	7
RNA modifications act as regulators of cell death	7
N6-methyladenosine RNA modification and its interaction with regulatory non-coding RNAs in colorectal cancer	7
An overview of RNA splicing and functioning of splicing factors in land plant chloroplasts	7
An epigenetic ‘extreme makeover’: the methylation of flaviviral RNA (and beyond)	7
RGG-motif containing mRNA export factor Gbp2 acts as a translation repressor	7
Towards the mechanism(s) of YB-3 synthesis regulation by YB-1	7
Substrate recognition mechanism of tRNA-targeting ribonuclease, colicin D, and an insight into tRNA cleavage-mediated translation impairment	7
Target-capture full-length double-strand cDNA sequencing for alternative splicing analysis	7
Competitive learning suggests circulating miRNA profiles for cancers decades prior to diagnosis	7
An introduction to PIWI-interacting RNAs (piRNAs) in the context of metazoan small RNA silencing pathways	7
A novel lncRNA derived from an ultraconserved region: lnc-uc.147, a potential biomarker in luminal A breast cancer	7
Exosomes provide unappreciated carrier effects that assist transfers of their miRNAs to targeted cells; I. They are ‘The Elephant in the Room’	7
Type II anti-CRISPR proteins as a new tool for synthetic biology	7
PhasiRNAnalyzer: an integrated analyser for plant phased siRNAs	7
Transposon clusters as substrates for aberrant splice-site activation	7
Annexin A2 binds the internal ribosomal entry site of c-myc mRNA and regulates its translation	7