Nature Structural & Molecular Biology

Papers
(The H4-Index of Nature Structural & Molecular Biology is 53. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Publisher Correction: Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane595
Structural insights into metazoan pretargeting GET complexes448
Author Correction: Polλ promotes microhomology-mediated end-joining294
Celebrating Nature Structural & Molecular Biology’s 30th anniversary275
ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism215
P-type ATPase magnesium transporter MgtA acts as a dimer190
30 years of structural and molecular biology and counting138
Alternative splicing of CARM1 regulated by LincGET-guided paraspeckles biases the first cell fate in mammalian early embryos129
A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens129
The Ruminococcus bromii amylosome protein Sas6 binds single and double helical α-glucan structures in starch128
A heterotrimeric protein complex assembles the metazoan V-ATPase upon dissipation of proton gradients120
Accessible technology for diploid high-order 3D human genome analysis118
Isoform-resolved mRNA profiling of ribosome load defines interplay of HIF and mTOR dysregulation in kidney cancer118
Author Correction: Structure of the human K2P13.1 channel reveals a hydrophilic pore restriction and lipid cofactor site97
Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication–transcription complex94
A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction87
Structural basis of tRNA recognition by the m3C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase86
Structural insights into translocation and tailored synthesis of hyaluronan85
Protein import into mitochondria — a new path through the membranes82
Structure of the HCV glycoprotein82
Exploration of novel αβ-protein folds through de novo design81
Surviving under stress conditions80
TRIM37 prevents ectopic spindle pole assembly by peptide motif recognition and substrate-dependent oligomerization77
Shifting our perspective on orphan G protein-coupled receptors77
Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex76
Cryo-EM analysis of complement C3 reveals a reversible major opening of the macroglobulin ring75
Dissecting the mechanism of CRISPR–Cas technologies to design efficient biotechnologies74
Transcription directionality is licensed by Integrator at active human promoters73
Tau modification by the norepinephrine metabolite DOPEGAL stimulates its pathology and propagation73
PARylated PDHE1α generates acetyl-CoA for local chromatin acetylation and DNA damage repair72
Snapshots of actin and tubulin folding inside the TRiC chaperonin72
Structures of aberrant spliceosome intermediates on their way to disassembly71
Endocrine resistance and breast cancer plasticity are controlled by CoREST69
Structural basis of branching during RNA splicing68
Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transport68
Constitutive activation mechanism of a class C GPCR67
Uncovering protein glycosylation dynamics and heterogeneity using deep quantitative glycoprofiling (DQGlyco)63
Reduction of DHHC5-mediated beclin 1 S-palmitoylation underlies autophagy decline in aging62
Current challenges in understanding the role of enhancers in disease60
Studying the impact of the nuclear topography on gene function59
Nature, more than nurture, of epigenetic states58
Binding NEMO: Liquid–liquid phase separation captures immune regulator58
THEMIS is a substrate and allosteric activator of SHP1, playing dual roles during T cell development57
Transcription start site choice diversifies mRNA isoforms and defines cancer cell behavior57
Author Correction: Structural basis of tRNA recognition by the m3C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase57
Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism56
Comprehensive analysis of Saccharomyces cerevisiae intron structures in vivo55
The conformational landscape of human transthyretin revealed by cryo-EM55
Lineage regulators TFAP2C and NR5A2 function as bipotency activators in totipotent embryos54
Cryogenic electron microscopy structures reveal how ATP and DNA binding in MutS coordinates sequential steps of DNA mismatch repair54
DNA methylation restricts coordinated germline and neural fates in embryonic stem cell differentiation54
Author Correction: Cryo-EM structure of an active central apparatus53
Building insights into KRAS signaling complexes53
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