OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Structural & Molecular Biology is 59. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-06-01 to 2024-06-01.)

Article	Citations
SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects	470
Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis	466
SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation	440
Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2	419
Controlling the SARS-CoV-2 spike glycoprotein conformation	371
Structure and drug binding of the SARS-CoV-2 envelope protein transmembrane domain in lipid bilayers	285
A structural biology community assessment of AlphaFold2 applications	270
Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion	266
A thermostable, closed SARS-CoV-2 spike protein trimer	260
Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient	258
Enhancer RNAs are an important regulatory layer of the epigenome	218
AlphaFold2 and the future of structural biology	210
Structure, lipid scrambling activity and role in autophagosome formation of ATG9A	201
Can AlphaFold2 predict the impact of missense mutations on structure?	186
Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation	175
Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs	172
Structure-guided covalent stabilization of coronavirus spike glycoprotein trimers in the closed conformation	154
Structural basis for broad coronavirus neutralization	149
Cryo-EM structure of the entire mammalian F-type ATP synthase	127
Effect of SARS-CoV-2 B.1.1.7 mutations on spike protein structure and function	121
Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-β fibrils	119
The molecular structure of mammalian primary cilia revealed by cryo-electron tomography	119
Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies	118
Molnupiravir: coding for catastrophe	115
GPCR activation mechanisms across classes and macro/microscales	112

Targeted protein degradation as a powerful research tool in basic biology and drug target discovery	112
Cryo-EM structure of an amyloid fibril formed by full-length human prion protein	110
Decoding mRNA translatability and stability from the 5′ UTR	110
A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent	107
Structural basis for inhibition of the SARS-CoV-2 RNA polymerase by suramin	105
TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS	104
Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation	104
Heat-dependent opening of TRPV1 in the presence of capsaicin	104
It’s not just a phase: function and characteristics of RNA-binding proteins in phase separation	101
Cryo-EM structure and inhibitor design of human IAPP (amylin) fibrils	100
Structures of radial spokes and associated complexes important for ciliary motility	97
Towards a structurally resolved human protein interaction network	96
Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism	94
Mitochondrial complex I structure reveals ordered water molecules for catalysis and proton translocation	91
Dnmt1 has de novo activity targeted to transposable elements	89
The SARS-CoV-2 spike reversibly samples an open-trimer conformation exposing novel epitopes	86
Molecular mechanism for rotational switching of the bacterial flagellar motor	85
Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads	82
Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome	81
Single-gene imaging links genome topology, promoter–enhancer communication and transcription control	80
Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel	80
Cryo-EM structure of an activated GPCR–G protein complex in lipid nanodiscs	79
Structural basis of nucleosome transcription mediated by Chd1 and FACT	76
Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly	71
PARP inhibition impedes the maturation of nascent DNA strands during DNA replication	71
Structural insights into the regulation of human serine palmitoyltransferase complexes	69
Dimers of DNA-PK create a stage for DNA double-strand break repair	64
Cold sensitivity of the SARS-CoV-2 spike ectodomain	64
Multi-contact 3C reveals that the human genome during interphase is largely not entangled	64
Endogenous retroviruses drive species-specific germline transcriptomes in mammals	63
Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression	62
PRC1 drives Polycomb-mediated gene repression by controlling transcription initiation and burst frequency	60
Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism	60
Structural insights into the assembly and substrate selectivity of human SPT–ORMDL3 complex	59