Nature Structural & Molecular Biology

Papers
(The H4-Index of Nature Structural & Molecular Biology is 56. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Celebrating Nature Structural & Molecular Biology’s 30th anniversary586
30 years of structural and molecular biology and counting241
Structural basis of branching during RNA splicing164
Structures of aberrant spliceosome intermediates on their way to disassembly139
Reduction of DHHC5-mediated beclin 1 S-palmitoylation underlies autophagy decline in aging122
Structural basis of tRNA recognition by the m3C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase117
Exploration of novel αβ-protein folds through de novo design115
The Ruminococcus bromii amylosome protein Sas6 binds single and double helical α-glucan structures in starch108
Alternative splicing of CARM1 regulated by LincGET-guided paraspeckles biases the first cell fate in mammalian early embryos104
Surviving under stress conditions101
TRIM37 prevents ectopic spindle pole assembly by peptide motif recognition and substrate-dependent oligomerization98
Author Correction: Polλ promotes microhomology-mediated end-joining97
Publisher Correction: Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane94
P-type ATPase magnesium transporter MgtA acts as a dimer92
Author Correction: Structure of the human K2P13.1 channel reveals a hydrophilic pore restriction and lipid cofactor site92
Shifting our perspective on orphan G protein-coupled receptors91
Dissecting the mechanism of CRISPR–Cas technologies to design efficient biotechnologies91
Transcription directionality is licensed by Integrator at active human promoters90
Structural insights into translocation and tailored synthesis of hyaluronan81
Isoform-resolved mRNA profiling of ribosome load defines interplay of HIF and mTOR dysregulation in kidney cancer79
A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens77
ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism77
Charting the 3D regulatory landscape of sex determination with geostatistics76
Author Correction: Structure and mechanism of antiphage retron Eco276
Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex75
Endocrine resistance and breast cancer plasticity are controlled by CoREST71
A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction70
PARylated PDHE1α generates acetyl-CoA for local chromatin acetylation and DNA damage repair69
Uncovering protein glycosylation dynamics and heterogeneity using deep quantitative glycoprofiling (DQGlyco)69
Structure of the HCV glycoprotein68
Towards a molecular and structural definition of cell death68
Protein import into mitochondria — a new path through the membranes68
Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transport68
A heterotrimeric protein complex assembles the metazoan V-ATPase upon dissipation of proton gradients68
Constitutive activation mechanism of a class C GPCR67
Current challenges in understanding the role of enhancers in disease67
Gene regulation through exon junction complex modularity67
Cryo-EM analysis of complement C3 reveals a reversible major opening of the macroglobulin ring64
Accessible technology for diploid high-order 3D human genome analysis63
Binding NEMO: Liquid–liquid phase separation captures immune regulator63
Studying the impact of the nuclear topography on gene function62
Cohesin closes the door on coexpression61
Cryo-EM structure of an active central apparatus61
A personal perspective of the voltage-gated potassium channel studies60
Addendum: Retinoic acid signaling is critical during the totipotency window in early mammalian development60
Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM60
Transcription start site choice diversifies mRNA isoforms and defines cancer cell behavior60
Author Correction: Cryo-EM structure of an active central apparatus59
Better SIFI than sorry59
Chemical modifications, ions and water molecules in the sub-2 Å resolution structure of the human 80S ribosome59
Author Correction: Structural basis of the histone ubiquitination read–write mechanism of RYBP–PRC158
Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex57
Cryo-EM structure of the NDH–PSI–LHCI supercomplex from Spinacia oleracea57
Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport57
Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia56
Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening56
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