Nature Structural & Molecular Biology

Papers
(The H4-Index of Nature Structural & Molecular Biology is 53. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Publisher Correction: Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane490
Author Correction: Polλ promotes microhomology-mediated end-joining290
Author Correction: Structure of the human K2P13.1 channel reveals a hydrophilic pore restriction and lipid cofactor site243
Shifting our perspective on orphan G protein-coupled receptors210
Celebrating Nature Structural & Molecular Biology’s 30th anniversary140
Tau modification by the norepinephrine metabolite DOPEGAL stimulates its pathology and propagation139
Constitutive activation mechanism of a class C GPCR136
30 years of structural and molecular biology and counting132
Structural basis of tRNA recognition by the m3C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase114
Exploration of novel αβ-protein folds through de novo design100
A heterotrimeric protein complex assembles the metazoan V-ATPase upon dissipation of proton gradients98
Towards a molecular and structural definition of cell death96
Isoform-resolved mRNA profiling of ribosome load defines interplay of HIF and mTOR dysregulation in kidney cancer94
Endocrine resistance and breast cancer plasticity are controlled by CoREST90
Transcription directionality is licensed by Integrator at active human promoters86
Uncovering protein glycosylation dynamics and heterogeneity using deep quantitative glycoprofiling (DQGlyco)86
A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction85
Dissecting the mechanism of CRISPR–Cas technologies to design efficient biotechnologies83
Structural insights into metazoan pretargeting GET complexes81
Snapshots of actin and tubulin folding inside the TRiC chaperonin81
Accessible technology for diploid high-order 3D human genome analysis79
Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex78
Surviving under stress conditions75
TRIM37 prevents ectopic spindle pole assembly by peptide motif recognition and substrate-dependent oligomerization73
Alternative splicing of CARM1 regulated by LincGET-guided paraspeckles biases the first cell fate in mammalian early embryos69
Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transport69
Structure of the HCV glycoprotein69
A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens69
The Ruminococcus bromii amylosome protein Sas6 binds single and double helical α-glucan structures in starch68
Protein import into mitochondria — a new path through the membranes67
ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism67
Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication–transcription complex63
Structures of aberrant spliceosome intermediates on their way to disassembly62
Structural insights into translocation and tailored synthesis of hyaluronan62
Structural basis of branching during RNA splicing60
P-type ATPase magnesium transporter MgtA acts as a dimer60
Cryo-EM analysis of complement C3 reveals a reversible major opening of the macroglobulin ring59
Reduction of DHHC5-mediated beclin 1 S-palmitoylation underlies autophagy decline in aging59
Current challenges in understanding the role of enhancers in disease59
PARylated PDHE1α generates acetyl-CoA for local chromatin acetylation and DNA damage repair59
Studying the impact of the nuclear topography on gene function58
Binding NEMO: Liquid–liquid phase separation captures immune regulator58
Author Correction: Cryo-EM structure of an active central apparatus56
Cohesin closes the door on coexpression56
Author Correction: Structural basis of the histone ubiquitination read–write mechanism of RYBP–PRC156
Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM56
Comprehensive analysis of Saccharomyces cerevisiae intron structures in vivo55
Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport54
Transcription start site choice diversifies mRNA isoforms and defines cancer cell behavior54
A personal perspective of the voltage-gated potassium channel studies54
Rhodopsin-bestrophin fusion proteins from unicellular algae form gigantic pentameric ion channels53
Chemical modifications, ions and water molecules in the sub-2 Å resolution structure of the human 80S ribosome53
Better SIFI than sorry53
EGOC inhibits TOROID polymerization by structurally activating TORC153
cBAF generates subnucleosomes that expand OCT4 binding and function beyond DNA motifs at enhancers53
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