OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Structural & Molecular Biology is 55. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Celebrating Nature Structural & Molecular Biology’s 30th anniversary	635
Surviving under stress conditions	256
Dissecting the mechanism of CRISPR–Cas technologies to design efficient biotechnologies	151
30 years of structural and molecular biology and counting	128
Structure of the HCV glycoprotein	125
Author Correction: Polλ promotes microhomology-mediated end-joining	122
Publisher Correction: Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane	115
Author Correction: Structure of the human K2P13.1 channel reveals a hydrophilic pore restriction and lipid cofactor site	109
Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex	104
ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism	101
Author Correction: Structure and mechanism of antiphage retron Eco2	99
Charting the 3D regulatory landscape of sex determination with geostatistics	98
Structural basis of branching during RNA splicing	97
Cryo-EM analysis of complement C3 reveals a reversible major opening of the macroglobulin ring	84
Constitutive activation mechanism of a class C GPCR	84
Accessible technology for diploid high-order 3D human genome analysis	83
Isoform-resolved mRNA profiling of ribosome load defines interplay of HIF and mTOR dysregulation in kidney cancer	81
Endocrine resistance and breast cancer plasticity are controlled by CoREST	78
Protein import into mitochondria — a new path through the membranes	77
A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens	76
Gene regulation through exon junction complex modularity	74
Shifting our perspective on orphan G protein-coupled receptors	73
Yolk transports miRNAs to embryos and enhances progeny stress resilience	73
Towards a molecular and structural definition of cell death	73
Structural basis of tRNA recognition by the m3C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase	72

P-type ATPase magnesium transporter MgtA acts as a dimer	72
A heterotrimeric protein complex assembles the metazoan V-ATPase upon dissipation of proton gradients	70
A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction	70
Structural insights into translocation and tailored synthesis of hyaluronan	70
Current challenges in understanding the role of enhancers in disease	68
Alternative splicing of CARM1 regulated by LincGET-guided paraspeckles biases the first cell fate in mammalian early embryos	68
Exploration of novel αβ-protein folds through de novo design	68
Uncovering protein glycosylation dynamics and heterogeneity using deep quantitative glycoprofiling (DQGlyco)	66
Reduction of DHHC5-mediated beclin 1 S-palmitoylation underlies autophagy decline in aging	66
PARylated PDHE1α generates acetyl-CoA for local chromatin acetylation and DNA damage repair	66
The Ruminococcus bromii amylosome protein Sas6 binds single and double helical α-glucan structures in starch	65
Transcription directionality is licensed by Integrator at active human promoters	65
TRIM37 prevents ectopic spindle pole assembly by peptide motif recognition and substrate-dependent oligomerization	64
Structures of aberrant spliceosome intermediates on their way to disassembly	64
Studying the impact of the nuclear topography on gene function	63
Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transport	63
A personal perspective of the voltage-gated potassium channel studies	61
Cohesin closes the door on coexpression	61
Transcription start site choice diversifies mRNA isoforms and defines cancer cell behavior	60
Addendum: Retinoic acid signaling is critical during the totipotency window in early mammalian development	60
Author Correction: Cryo-EM structure of an active central apparatus	57
EGOC inhibits TOROID polymerization by structurally activating TORC1	57
Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM	57
Chemical modifications, ions and water molecules in the sub-2 Å resolution structure of the human 80S ribosome	57
Checking in on proteostasis	57
Better SIFI than sorry	57
Author Correction: Structural basis of the histone ubiquitination read–write mechanism of RYBP–PRC1	56
MitoPerturb-Seq identifies gene-specific single-cell responses to mitochondrial DNA depletion and heteroplasmy	55
Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport	55
Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia	55