OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Structural & Molecular Biology is 55. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Celebrating Nature Structural & Molecular Biology’s 30th anniversary	602
Surviving under stress conditions	242
Dissecting the mechanism of CRISPR–Cas technologies to design efficient biotechnologies	167
30 years of structural and molecular biology and counting	145
Structure of the HCV glycoprotein	122
Shifting our perspective on orphan G protein-coupled receptors	121
The Ruminococcus bromii amylosome protein Sas6 binds single and double helical α-glucan structures in starch	116
Gene regulation through exon junction complex modularity	110
Protein import into mitochondria — a new path through the membranes	107
Author Correction: Polλ promotes microhomology-mediated end-joining	104
Publisher Correction: Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane	98
Author Correction: Structure of the human K2P13.1 channel reveals a hydrophilic pore restriction and lipid cofactor site	97
Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex	95
Author Correction: Structure and mechanism of antiphage retron Eco2	93
ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism	93
Charting the 3D regulatory landscape of sex determination with geostatistics	92
Structural basis of branching during RNA splicing	85
Structures of aberrant spliceosome intermediates on their way to disassembly	79
PARylated PDHE1α generates acetyl-CoA for local chromatin acetylation and DNA damage repair	78
Alternative splicing of CARM1 regulated by LincGET-guided paraspeckles biases the first cell fate in mammalian early embryos	78
Constitutive activation mechanism of a class C GPCR	77
Uncovering protein glycosylation dynamics and heterogeneity using deep quantitative glycoprofiling (DQGlyco)	77
Cryo-EM analysis of complement C3 reveals a reversible major opening of the macroglobulin ring	74
Accessible technology for diploid high-order 3D human genome analysis	73
Towards a molecular and structural definition of cell death	72

A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction	69
Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transport	69
Current challenges in understanding the role of enhancers in disease	69
A heterotrimeric protein complex assembles the metazoan V-ATPase upon dissipation of proton gradients	69
TRIM37 prevents ectopic spindle pole assembly by peptide motif recognition and substrate-dependent oligomerization	69
Isoform-resolved mRNA profiling of ribosome load defines interplay of HIF and mTOR dysregulation in kidney cancer	69
Exploration of novel αβ-protein folds through de novo design	69
A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens	68
Endocrine resistance and breast cancer plasticity are controlled by CoREST	65
Reduction of DHHC5-mediated beclin 1 S-palmitoylation underlies autophagy decline in aging	65
Structural basis of tRNA recognition by the m3C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase	65
Yolk transports miRNAs to embryos and enhances progeny stress resilience	64
Transcription directionality is licensed by Integrator at active human promoters	64
Structural insights into translocation and tailored synthesis of hyaluronan	64
P-type ATPase magnesium transporter MgtA acts as a dimer	63
Binding NEMO: Liquid–liquid phase separation captures immune regulator	62
A personal perspective of the voltage-gated potassium channel studies	61
Cohesin closes the door on coexpression	61
Transcription start site choice diversifies mRNA isoforms and defines cancer cell behavior	61
Studying the impact of the nuclear topography on gene function	61
Transcriptional repression upon S phase entry protects genome integrity in pluripotent cells	60
MitoPerturb-Seq identifies gene-specific single-cell responses to mitochondrial DNA depletion and heteroplasmy	60
THEMIS is a substrate and allosteric activator of SHP1, playing dual roles during T cell development	59
Smc5/6 silences episomal transcription by a three-step function	58
Addendum: Retinoic acid signaling is critical during the totipotency window in early mammalian development	58
Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia	57
The conformational landscape of human transthyretin revealed by cryo-EM	57
Chemical modifications, ions and water molecules in the sub-2 Å resolution structure of the human 80S ribosome	56
Dynamic PRC1–CBX8 stabilizes a porous structure of chromatin condensates	55
EGOC inhibits TOROID polymerization by structurally activating TORC1	55
Better SIFI than sorry	55
Comprehensive analysis of Saccharomyces cerevisiae intron structures in vivo	55