OOIR: Observatory of International Research

Papers

(The H4-Index of IEEE-ACM Transactions on Computational Biology and Bioinformatics is 41. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Gene Co-Expression Networks Offer New Perspectives on Sepsis Pathophysiology	528
Row and Column Structure-Based Biclustering for Gene Expression Data	271
Inference of a Dynamic Aging-related Biological Subnetwork via Network Propagation	146
Data-Driven and Knowledge-Based Algorithms for Gene Network Reconstruction on High-Dimensional Data	113
POPBic: Pathway-Based Order Preserving Biclustering Algorithm Towards the Analysis of Gene Expression Data	96
New Labeling Methods for Deep Learning Real-Valued Inter-Residue Distance Prediction	96
Prediction of Transcription Factor Binding Sites With an Attention Augmented Convolutional Neural Network	85
RNASeqR: An R Package for Automated Two-Group RNA-Seq Analysis Workflow	84
Contrasting Multi-Source Temporal Knowledge Graphs for Biomedical Hypothesis Generation	75
Protein-Protein Interaction Sites Prediction Using Batch Normalization Based CNNs and Oversampling Method Borderline-SMOTE	68
Seq-BEL: Sequence-Based Ensemble Learning for Predicting Virus-Human Protein-Protein Interaction	67
An Ensemble Tf-Idf Based Approach to Protein Function Prediction via Sequence Segmentation	66
IPP: An Intelligent Privacy-Preserving Scheme for Detecting Interactions in Genome Association Studies	66
Graph Convolutional Auto-Encoders for Predicting Novel lncRNA-Disease Associations	65
GraphPlas: Refined Classification of Plasmid Sequences Using Assembly Graphs	64
Higher-Order Proximity-Based MiRNA-Disease Associations Prediction	63
Protein Fold Recognition by Combining Support Vector Machines and Pairwise Sequence Similarity Scores	59
scBKAP: A Clustering Model for Single-Cell RNA-Seq Data Based on Bisecting K-Means	58
An Effective Swarm Intelligence Optimization Algorithm for Flexible Ligand Docking	56
Compressed Sparse FM-Index: Fast Sequence Alignment Using Large K-Steps	54
An Automated Cell Tracking Approach With Multi-Bernoulli Filtering and Ant Colony Labor Division	54
ELMo4m6A: A Contextual Language Embedding-Based Predictor for Detecting RNA N6-Methyladenosine Sites	53
Analysis of Cancer-Associated Mutations of POLB Using Machine Learning and Bioinformatics	53
VMF-SSD: A Novel V-Space Based Multi-Scale Feature Fusion SSD for Apple Leaf Disease Detection	51
IGNSCDA: Predicting CircRNA-Disease Associations Based on Improved Graph Convolutional Network and Negative Sampling	51

Hybrid Projective Synchronization via PI Controller Based on DNA Strand Displacement	51
The Determination of Distinctive Single Nucleotide Polymorphism Sets for the Diagnosis of Behçet's Disease	50
Predicting Drug-Drug Interactions Based on Integrated Similarity and Semi-Supervised Learning	49
Modality-DTA: Multimodality Fusion Strategy for Drug–Target Affinity Prediction	49
Improving Biomedical Question Answering by Data Augmentation and Model Weighting	48
State Observer Design of Coupled Genetic Regulatory Networks With Reaction-Diffusion Terms via Time-Space Sampled-Data Communications	48
Prediction of circRNA-MiRNA Association Using Singular Value Decomposition and Graph Neural Networks	48
An Approach of Epistasis Detection Using Integer Linear Programming Optimizing Bayesian Network	46
Local R-Symmetry Co-Occurrence: Characterising Leaf Image Patterns for Identifying Cultivars	46
Spatial Stochastic Model of the Pre-B Cell Receptor	45
Minimum Functional Length Analysis of K-Mer Based on BPNN	45
Analyzing Effect of Multi-Modality in Predicting Protein-Protein Interactions	45
Optimized Elastic Network Models With Direct Characterization of Inter-Residue Cooperativity for Protein Dynamics	44
SGNet: Sequence-Based Convolution and Ligand Graph Network for Protein Binding Affinity Prediction	42
PseU-KeMRF: A Novel Method for Identifying RNA Pseudouridine Sites	42
Blockchain-Based Data Access Security Solutions for Medical Wearables	42
Subgroup Identification Using Virtual Twins for Human Microbiome Studies	41
Fine-Grained Lesion Classification Framework for Early Auxiliary Diagnosis	41
Automated Spot Counting in Microbiology	41
Feature Fusion GAN Based Virtual Staining on Plant Microscopy Images	41
A Multi-Task Deep Feature Selection Method for Brain Imaging Genetics	41