OOIR: Observatory of International Research

Papers

(The median citation count of Molecular Pharmaceutics is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Novel 5-Fluorouracil Carbonate-Loaded Liposome: Preparation, In Vitro, and In Vivo Evaluation as an Antitumor Agent	316
Correlating Surface Activity with Interface-Induced Aggregation in a High-Concentration mAb Solution	102
Radiosynthesis and Preliminary Evaluation of [¹¹C]SSI-4 for the Positron Emission Tomography Imaging of Stearoyl CoA Desaturase 1	85
Issue Editorial Masthead	83
Multifunctional Nanotheranostics for Dual-Modal Imaging-Guided Precision Therapy of Nasopharyngeal Carcinoma	68
Mathematical Modeling and Experimental Validation of Extracellular Vesicle-Mediated Tumor Suppressor MicroRNA Delivery and Propagation in Ovarian Cancer Cells	64
PEGylation Improves the Therapeutic Index of Dexamethasone To Treat Acute Respiratory Distress Syndrome with Obesity Background in Mouse	64
Exploring the Potent Combination of Quercetin–Boronic Acid, Epalrestat, and Urea Containing Nanoethosomal Keratolytic Gel for the Treatment of Diabetic Neuropathic Pain: In Vitro and In Vivo Studies	64
Atomic Insights into pH-Dependent and Water Permeation of mRNA-Lipid Nanoparticles	63
Surface-Engineered Polygonatum Sibiricum Polysaccharide CaCO₃ Microparticles as Novel Vaccine Adjuvants to Enhance Immune Response	56
Construction of [⁸⁹Zr]Zr-Labeled HuL13 for ImmunoPET Imaging of LAG-3 Checkpoint Expression on Tumor-Infiltrating T Cells	55
Evaluation of a Positron Emission Tomography Tracer Targeting Colony-Stimulating Factor 1 Receptor for Detecting Pulmonary Inflammation	54
Development and Validation of Novel Z-360-Based Macromolecules for the Active Targeting of CCK2-R	51
Development of Broad-Spectrum Nanobodies for the Therapy and Diagnosis of SARS-CoV-2 and Its Multiple Variants	50
A Biopharmaceutical Perspective on Higher-Order Structure and Thermal Stability of mRNA Vaccines	49
The Relationship between Protein–Protein Interactions and Liquid–Liquid Phase Separation for Monoclonal Antibodies	49
Head-to-Head Comparison of Caco-2 Transwell and Gut-on-a-Chip Models for Assessing Oral Peptide Formulations	49
Correction to “Dissolution Mechanisms of Amorphous Solid Dispersions: A Close Look at the Dissolution Interface”	48
Quabodepistat (OPC-167832), a Novel Antituberculosis Drug Candidate: Enhancing Oral Bioavailability via Cocrystallization and Mechanistic Analysis of Bioavailability in Two Cocrystals	46
Messenger RNA Therapy for Female Reproductive Health	45
Ocular Pharmacokinetics of Intravitreally Injected Protein Therapeutics: Comparison among Standard-of-Care Formats	45
Introducing the Molecular Pharmaceutics Special Issue on Industrial Drug Delivery─In Silico to Bedside	44
Impact of Drug–Polymer Intermolecular Interactions on Dissolution Performance of Copovidone-Based Amorphous Solid Dispersions	44
Issue Editorial Masthead	42
Two-Chain Mature Hepatocyte Growth Factor-Specific Positron Emission Tomography Imaging in Tumors Using ⁶⁴Cu-Labeled HiP-8, a Nonstandard Macrocyclic Peptide Probe	41

The Transition from Academia to Industry as an Early Career Scientist: The Why, the How, and the What	40
Issue Publication Information	40
Transforming a Toxic Non-Ionizable Drug into an Efficacious Liposome via Ionizable Prodrug and Remote Loading Strategies against Malignant Breast Tumors	39
PD-L1 Blockade Peptide-Modified Polymeric Nanoparticles for Oxygen-Independent-Based Hypoxic Tumor Photo/Thermodynamic Immunotherapy	38
Mesoporous Matrices as a Promising New Generation of Carriers for Multipolymorphic Active Pharmaceutical Ingredient Aripiprazole	37
Pretargeted PET of Osteodestructive Lesions in Dogs	37
Functionalization of Radiolabeled Antibodies to Enhance Peripheral Clearance for High Contrast Brain Imaging	37
Tit for Tat: An Unacknowledged Institutional Response to Targets of Academic Bullying and Harassment	36
The Potency of Cowpea Mosaic Virus Particles for Cancer In Situ Vaccination Is Unaffected by the Specific Encapsidated Viral RNA	35
Pharmacokinetics in Penguins Compared to Other Avian Species: A Review of Enrofloxacin and Voriconazole	35
Exploration of Verticillins in High-Grade Serous Ovarian Cancer and Evaluation of Multiple Formulations in Preclinical In Vitro and In Vivo Models	34
Molecular Dynamics Study of Protein Aggregation at Moving Interfaces	33
Strategic Assessment of Boron-Enriched Carbon Dots/Naproxen: Diagnostic, Toxicity, and In Vivo Therapeutic Evaluation	33
Immunotherapy Study on Non-small-Cell Lung Cancer (NSCLC) Combined with Cytotoxic T Cells and miRNA34a	33
In Vivo Mechanism of Action of Sodium Caprate for Improving the Intestinal Absorption of a GLP1/GIP Coagonist Peptide	33
Development of a Cytosolic DNA Sensor Agonist Using GALA Peptide-Conjugated DNA and Long Single-Stranded DNA	33
Predicting Experimental B₂₂ Values and the Effects of Histidine Charge States for Monoclonal Antibodies Using Coarse-Grained Molecular Simulations	33
In Situ Monitoring of Competitive Coformer Exchange Reaction by ¹H MAS Solid-State NMR	32
PDGFRβ-Antagonistic Affibody-Mediated Tumor-Targeted Tumor Necrosis Factor-Alpha for Enhanced Radiotherapy in Lung Cancer	32
A Modular Albumin-Oligonucleotide Biomolecular Assembly for Delivery of Antisense Therapeutics	31
Controlled Sublimation Rate of Guest Drug from Polymorphic Forms of a Cyclodextrin-Based Polypseudorotaxane Complex and Its Correlation with Molecular Dynamics as Probed by Solid-State NMR	31
Reviving Intervertebral Discs: Treating Degeneration Using Advanced Delivery Systems	31
Design, Synthesis, and Biological Evaluation of Novel Nonsteroidal ¹⁸F-Labeled PET Probes Specifically Targeting Estrogen Receptor α	30
Chemically Driven Clearance of Amyloid Aggregates by Polyfunctionalized Furo[2,3-b:4,5-b′]dipyridine–Chalcone Hybrids to Ameliorate Memory in an Alzheimer Mouse Model	30
Protecting Lyophilized Escherichia coli Adenylate Kinase	30
Molecular SPECT/CT Profiling of Claudin18.2 Expression In Vivo: Implication for Patients with Gastric Cancer	30
Issue Editorial Masthead	29
PET Imaging of Bromodomain and Extra-Terminal Domain Inhibitors for the Noninvasive Assessment of Metabolic Changes in the Liver and Brain of Early-Stage Alcoholic Liver Disease	29
Understanding the Roles of Excipients in Moisture Management in Solid Dosage Forms	28
[¹⁸F]F-ET-OTSSP167 Targets Maternal Embryo Leucine Zipper Kinase for PET Imaging of Triple-Negative Breast Cancer	28
A Polyplex in a Shell: The Effect of Poly(aspartic acid)-Mediated Calcium Carbonate Mineralization on Polyplexes Properties and Transfection Efficiency	28
TNF-α and IL-1β Exposure Modulates the Expression and Functionality of P-Glycoprotein in Intestinal and Renal Barriers	28
Novel Radiolabeled TMTP1 for Long-Acting Hepatocellular Carcinoma Therapeutics	28
Issue Publication Information	28
The Influence of PVP Polymer Topology on the Liquid Crystalline Order of Itraconazole in Binary Systems	27
In Vitro Release from Polymeric Core/Shell Nanoparticles through the Lens of Multiscale Modeling	27
Nanotheranostics: Molecular Diagnostics and Nanotherapeutic Evaluation by Photoacoustic/Ultrasound Imaging in Small Animals	27
Radiosynthesis and Preclinical Evaluation of m-[¹⁸F]FET and [¹⁸F]FET-OMe as Novel [¹⁸F]FET Analogs for Brain Tumor Imaging	27
Issue Editorial Masthead	26
Saponin and Ribosome-Inactivating Protein Synergistically Trigger Lysosome-Dependent Apoptosis by Inhibiting Lysophagy: Potential to Become a New Antitumor Strategy	26
Exploring Bimetallic Nanoparticles in Alzheimer’s Therapy: A Novel Bio-Assisted Synthesis with Multitarget Potential	26
Simultaneous Water Sorption and Crystallization in ASDs 1: Stability Studies Lasting for Two Years	25
Preclinical Evaluation of a Fibroblast Activation Protein and a Prostate-Specific Membrane Antigen Dual-Targeted Probe for Noninvasive Prostate Cancer Imaging	25
Photolytic Removal of Red Blood Cell Membranes Camouflaged on Nanoparticles for Enhanced Cellular Uptake and Combined Chemo-Photodynamic Inhibition of Cancer Cells	25
Nanomedicine for Drug Delivery throughout the Alimentary Canal	25
Influence of Water on Amorphous Lidocaine	25
Preclinical Evaluation and a Pilot Clinical Positron Emission Tomography Imaging Study of [⁶⁸Ga]Ga-FAPI-FUSCC-II	25
Photoactivated Gallium Porphyrin Reduces Staphylococcus aureus Colonization on the Skin and Suppresses Its Ability to Produce Enterotoxin C and TSST-1	25
Co-administration of Intravenous Drugs: Rapidly Troubleshooting the Solid Form Composition of a Precipitate in a Multi-drug Mixture Using On-Site Raman Spectroscopy	24
Synthesis and Evaluation of [¹¹C]MCC950 for Imaging NLRP3-Mediated Inflammation in Atherosclerosis	24

Enhancing the Endocytosis of Phosphatidylserine-Containing Liposomes through Tim4 by Modulation of Membrane Fluidity	24
Mouse Bone Marrow Mesenchymal Stem Cells Inhibit Sepsis-Induced Lung Injury in Mice via Exosomal SAA1	24
Design of Redispersible High-Drug-Load Amorphous Formulations: Impact of Ionic vs Nonionic Surfactants on Processing and Performance	24
Studying Drug Release through Polymeric Controlled Release Formulations in United States Pharmacopoeia 2 Apparatus Using Multiphysics Simulation and Experiments	24
An In Vitro Model for Cocrystal Dissolution with Simultaneous Surface and Bulk Precipitation	24
Effect of Extracellular Matrix Coating on Cancer Cell Membrane-Encapsulated Polyethyleneimine/DNA Complexes for Efficient and Targeted DNA Delivery In Vitro	24
Mapping of Translocator Protein (18 kDa) in Peripheral Sterile Inflammatory Disease and Cancer through PET Imaging	24
Issue Publication Information	23
Defining the Intravital Renal Disposition of Fluorescence-Quenched Exenatide	23
Penetration of Vancomycin into Noninfected Bone in Patients Undergoing Total Joint Arthroplasty Evaluated by a Minimal Physiologically Based Population Pharmacokinetic Modeling Approach	23
Effect of ‘pH’ on the Rate of Pyroglutamate Formation in Solution and Lyophilized Solids	22
Voices in Molecular Pharmaceutics: Meet Dr. Yongchao Su, Innovating at the Molecular Level	22
Improved Photodynamic Activity of Phthalocyanine by Adjusting the Chirality of Modified Amino Acids	22
Introducing the Molecular Pharmaceutics Special Issue on “Tiny Things, Big Impact: Nanomedicine in Canada”	22
Surface-Functionalized Stem Cell-Derived Extracellular Vesicles for Vascular Elastic Matrix Regenerative Repair	22
Preparation of a Self-Assembled Rhein–Doxorubicin Nanogel Targeting Mitochondria and Investigation on Its Antihepatoma Activity	22
Correction to Altered Expression of Small Intestinal Drug Transporters and Hepatic Metabolic Enzymes in a Mouse Model of Familial Alzheimer’s Disease	22
Recrystallization of Adenosine for Localized Drug Delivery	21
Introducing the Molecular Pharmaceutics Virtual Special Issue on “Advances in Molecular Pharmaceutical Research from Asia”	21
Introducing the Molecular Pharmaceutics Special Issue on “Interdisciplinary Integration of Biomaterials for Drug and Gene Therapy”	21
Voices in Molecular Pharmaceutics: Meet Dr. Dana Moseson, Tackling the Next Generation of Amorphous Solid Dispersion Formulation and Manufacturing Challenges	21
Issue Publication Information	21
Issue Editorial Masthead	21
A Model Study to Assess Fibrillation and Product Stability to Support Peptide Drug Design	20
Tinagl1 Gene Therapy Suppresses Growth and Remodels the Microenvironment of Triple Negative Breast Cancer	20
Distribution of Female and Male First and Last Authorship across Drug Delivery Related Journals with Respect to Year and Journal Impact Factor	20
Combination Nano-Delivery Systems Remodel the Immunosuppressive Tumor Microenvironment for Metastatic Triple-Negative Breast Cancer Therapy	20
Deciphering the Lexicon of Protein Targets: A Review on Multifaceted Drug Discovery in the Era of Artificial Intelligence	20
A Potential Boron Neutron Capture Therapy Agent Selectively Suppresses High-Grade Glioma: In Vitro and in Vivo Exploration	20
Issue Publication Information	20
Combination of Molecule-Targeted Therapy and Photodynamic Therapy Using Nanoformulated Verteporfin for Effective Uveal Melanoma Treatment	20
Crystallization Propensity of Amorphous Pharmaceuticals: Kinetics and Thermodynamics	20
Highlighting the Contributions of the Editorial Advisory Board to Molecular Pharmaceutics	20
Gallium-68-Labeled Z_PDGFRβ Affibody: A Potential PET Probe for Platelet-Derived Growth Factor Receptor β-Expressing Carcinomas	19
Transporter Protein Expression of Corneal Epithelium in Rabbit and Porcine: Evaluation of Models for Ocular Drug Transport Study	19
Biological Fate Tracking of Nitric Oxide-Propelled Microneedle Delivery System Using an Aggregation-Caused Quenching Probe	19
High Molecular Weight Poly(glutamic acid) to Improve BMP2-Induced Osteogenic Differentiation	19
Lactoferrin-Modified Gambogic Acid Liposomes for Colorectal Cancer Treatment	19
Unraveling the Potential of Vitamin B₃-Derived Salts with a Salicylate Anion as Dermal Active Agents for Acne Treatment	19
Multicomponent Chiral Quantification with Ultraviolet Circular Dichroism Spectroscopy: Ternary and Quaternary Phase Diagrams of Levetiracetam	19
Gold Nanoparticle-Decorated Drug Nanocrystals for Enhancing Anticancer Efficacy and Reversing Drug Resistance Through Chemo-/Photothermal Therapy	19
Issue Publication Information	19
Impact of an Adenosine A_2A Receptor Agonist and Antagonist on Binding of the Dopamine D₂ Receptor Ligand [¹¹C]raclopride in the Rodent Striatum	18
Characterizing Protein–Protein Interactions and Viscosity of a Monoclonal Antibody from Low to High Concentration Using Small-Angle X-ray Scattering and Molecular Dynamics Simulations	18
Pharmacokinetic Bioequivalence between Generic and Originator Orally Inhaled Drug Products: Validity of Administration of Doses above the Approved Single Maximum Dose	18
Differential Surface Adsorption Phenomena for Conventional and Novel Surfactants Correlates with Changes in Interfacial mAb Stabilization	18
Investigation of Poor Solubility of a Salt-Cocrystal Hydrate: A Case Study of the Common-Ion Effect in Betrixaban, an Anticoagulant Drug	18
Influence of Hydrophobic and Hydrophilic Chain Length of C_iE_j Surfactants on the Solubilization of Active Pharmaceutical Ingredients	18
Characterization of Pediatric Rectal Absorption, Drug Disposition, and Sedation Level for Midazolam Gel Using Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling	18
Application of Mechanistic Multiparameter Optimization and Large-Scale In Vitro to In Vivo Pharmacokinetics Correlations to Small-Molecule Therapeutic Projects	18
Investigating the Impact of Crohn’s Disease on the Bioaccessibility of a Lipid-Based Formulation with an In Vitro Dynamic Gastrointestinal Model	18
Use of Gastrointestinal Simulator, Mass Transport Analysis, and Absorption Simulation to Investigate the Impact of pH Modifiers in Mitigating Weakly Basic Drugs’ Performance Issues Related to Gastric	18
Comparative Study of Latanoprost Drug Delivery Systems for Glaucoma Treatment and Their Interaction with the Tear Film Lipid Layer Models	18
Voices in Molecular Pharmaceutics: Meet Dr. Eloy Pena-Rodríguez, Nanoparticle Engineer for Transdermal Delivery	18
Monoclonal Antibody Delivery Using 3D Printed Biobased Hollow μNe3dle Arrays for the Treatment of Osteoporosis	18
Molecular Mechanism of Antimicrobial Excipient-Induced Aggregation in Parenteral Formulations of Peptide Therapeutics	18
Near UV and Visible Light Photodegradation in Solid Formulations: Generation of Carbon Dioxide Radical Anions from Citrate Buffer and Fe(III)	18
Versatile Nanoparticulate Systems as a Prosperous Platform for Targeted Nose–Brain Drug Delivery	18
Delivery and Expression of mRNA in the Secondary Lymphoid Organs Drive Immune Responses to Lipid Nanoparticle-mRNA Vaccines after Intramuscular Injection	18
pH-Responsive Liposomes Loaded with Targeting Procoagulant Proteins as Potential Embolic Agents for Solid Tumor-Targeted Therapy	18
Reversible Self-Association in Lactate Dehydrogenase during Freeze–Thaw in Buffered Solutions Using Neutron Scattering	18
Issue Editorial Masthead	17
Evaluation of a First PET Tracer Suitable for Imaging the Sigma-2 Receptor in the Brain of Nonhuman Primates	17
How Yoga Makes Me a Better Leader	17
Placental Therapeutic Targets and Nanodelivery Systems	17
Enhancement of Anti-inflammatory Effects of Synthetic High-Density Lipoproteins by Incorporation of Anionic Lipids	17
Fluorophore-Conjugated Anti-ICOS Antibody Enables Precise Prediction of Therapeutic Response of the STING Agonist in Colorectal Cancer via NIRF Imaging	17
Use of Peptide Microarrays for Fast and Informative Profiling of Therapeutic Antibody Formulation Conditions	17
Correction to “Targeted Theranostic ¹¹¹In/Lu-Nanotexaphyrin for SPECT Imaging and Photodynamic Therapy”	17
Emerging Process Modeling Capabilities for Dry Powder Operations for Inhaled Formulations	17
Digestion of Lipid-Based Formulations Not Only Mediates Changes to Absorption of Poorly Soluble Drugs Due to Differences in Solubilization But Also Reflects Changes to Thermodynamic Activity and Perme	17
Issue Editorial Masthead	17
Latanoprost-Loaded Nanotransfersomes Designed for Scalp Administration Enhance Keratinocytes Proliferation	17
Immuno-PET Imaging of TNF-α in Colitis Using ⁸⁹Zr-DFO-infliximab	17
Porphyrin-Based Brain Tumor-Targeting Agents: [⁶⁴Cu]Cu-porphyrin and [⁶⁴Cu]Cu-TDAP	17
Coupling Chlorin-Based Photosensitizers and Histone Deacetylase Inhibitors for Photodynamic Chemotherapy	17
ICG-Dimeric Her2-Specific Affibody Conjugates for Tumor Imaging and Photothermal Therapy for Her2-Positive Tumors	16
Metformin-Loaded Hyaluronic Acid-Derived Carbon Dots for Targeted Therapy against Hepatocellular Carcinoma by Glutamine Metabolic Reprogramming	16
A Facile Way To Improve the Bioavailability of Nanomedicine Based on the Threshold Theory	16
Structured Sponsorship: An Option for Improved Workplace Inclusion in the Pharmaceutical Sciences	16

Kinetics of Flavonoid Degradation and Controlled Release from Functionalized Magnetic Nanoparticles	16
Specific Binding of Leptin to Red Blood Cells Delivers a Pancreatic Hormone and Stimulates ATP Release	16
Issue Publication Information	16
Bile Is a Selective Elevator for Mucosal Mechanics and Transport	16
Interface-Engineered Paclitaxel-Based Hollow Mesoporous Organosilica Nanoplatforms for Photothermal-Enhanced Chemotherapy of Tumor	16
Enhanced Therapeutic Efficacy Against Melanoma through Exosomal Delivery of Hesperidin	16
Efficacy of Temozolomide-Conjugated Gold Nanoparticle Photothermal Therapy of Drug-Resistant Glioblastoma and Its Mechanism Study	16
Contribution of the Dynamic Intestinal Absorption Model (Diamod) to the Development of a Patient-Centric Drug Formulation	16
Micelles-in-Liposome Systems Obtained by Proliposomal Approach for Cannabidiol Delivery: Structural Features and Skin Penetration	16
Nebulization and In Vitro Upper Airway Deposition of Liposomal Carrier Systems	16
Restoring Endogenous Repair Mechanisms to Heal Chronic Wounds with a Multifunctional Wound Dressing	16
Zinc Carnosine Metal–Organic Coordination Polymer as a Potent Broadly Active Influenza Vaccine Platform with In Vitro Shelf-Stability	15
Tuning Mesoporous Silica Nanoparticles in Novel Avenues of Cancer Therapy	15
Novel ¹⁸F-Labeled PET Tracers Specific to Aromatase: Design, Synthesis, and Biological Evaluation	15
Stem Cell-Derived Extracellular Vesicles for Cancer Therapy and Tissue Engineering Applications	15
Importance of Gastric Secretion and the Rapid Gastric Emptying of Ingested Water along the Lesser Curvature (“Magenstraße”) in Predicting the In Vivo Performance of Liquid Oral Dosage Forms in the Fed	15
Mechanistic Investigation of Drug Supersaturation in the Presence of Polysorbates as Solubilizing Additives by Solution Nuclear Magnetic Resonance Spectroscopy	15
Development and Preclinical Evaluation of Radiolabeled Covalent G12C-Specific Inhibitors for Direct Imaging of the Oncogenic KRAS Mutant	15
Effect of pH on the Surface Layer of Molecular Crystals at the Solid–Liquid Interface	15
Bridging the Gap between Food Effects under Clinical Trial Conditions and Real Life: Modeling Delayed Gastric Emptying of Drug Substances and Gastric Content Volume Based on Meal Characteristics	15
Predicting Colloidal Stability of High-Concentration Monoclonal Antibody Formulations in Common Pharmaceutical Buffers Using Improved Polyethylene Glycol Induced Protein Precipitation Assay	15
Targeting Tn-Antigen-Positive Human Tumors with a Recombinant Human Macrophage Galactose C-Type Lectin	15
Stability Convergence in Antibody Coformulations	15
Phase-Field Model for Drug Release of Water-Swellable Filaments for Fused Filament Fabrication	15
A Review of Brain-Targeted Nonviral Gene-Based Therapies for the Treatment of Alzheimer’s Disease	15
Interaction of Phytocompounds of Echinacea purpurea with ABCB1 and ABCG2 Efflux Transporters	14
Relative Humidity Cycling: Implications on the Stability of Moisture-Sensitive Drugs in Solid Pharmaceutical Products	14
Studies on the Vitrified and Cryomilled Bosentan	14
Positron Emission Tomography Imaging of Autotaxin in Thyroid and Breast Cancer Models Using [¹⁸F]PRIMATX	14
Role for Carboxylic Acid Moiety in NSAIDs: Favoring the Binding at Site II of Bovine Serum Albumin	14
Photoimmunotherapy Retains Its Anti-Tumor Efficacy with Increasing Stromal Content in Heterotypic Pancreatic Cancer Spheroids	14
pH/Hyal-Responsive Surface-Charge Switchable Electrostatic Complexation for Efficient Elimination of MRSA Infection	14
Administration Routes of Polyethylenimine-Coated PLGA Nanoparticles Encapsulating Angelica Sinensis Polysaccharide Vaccine Delivery System Affect Immune Responses	14
Molecular Dynamics Simulations of Self-Assembling Colloids in Fed-State Human Intestinal Fluids and Their Solubilization of Lipophilic Drugs	14
Impact of Intestinal Concentration and Colloidal Structure on the Permeation-Enhancing Efficiency of Sodium Caprate in the Rat	14
Targeted Nanodrugs to Destroy the Tumor Extracellular Matrix Barrier for Improving Drug Delivery and Cancer Therapeutic Efficacy	14
Understanding the Impact of Protein–Excipient Interactions on Physical Stability of Spray-Dried Protein Solids	14
Conjugation to PEG as a Strategy to Limit the Uptake of Drugs by the Placenta: Potential Applications for Drug Administration in Pregnancy	14
Analysis of Cimetidine Crystal Polymorphs by X-ray Absorption Near-Edge Spectroscopy	14
Options of Therapeutics and Novel Delivery Systems of Drugs for the Treatment of Melanoma	14
Development of a Biomaterial Scaffold Integrated with Osteoinductive Oxysterol Liposomes to Enhance Hedgehog Signaling and Bone Repair	14
Experiences and Translatability of In Vitro and In Vivo Models to Evaluate Caprate as a Permeation Enhancer	14
Targeting Claudin 18.2 Using a Highly Specific Antibody Enables Cancer Diagnosis and Guided Surgery	14
Biodistribution Analysis of Peptide-Coated Magnetic Iron Nanoparticles: A Simple and Quantitative Method	14
Investigating Crystalline Protein Suspension Formulations of Pembrolizumab from MAS NMR Spectroscopy	14
Toward Understanding the Binding Synergy of Trastuzumab and Pertuzumab to Human Epidermal Growth Factor Receptor 2	14
Kinetic Modeling of API Oxidation: (2) Imipramine Stress Testing	13
First-in-Patient Dose Prediction for Adeno-Associated Virus-Mediated Hemophilia Gene Therapy Using Allometric Scaling	13
Influence of Nucleation on Relaxation, Molecular Cooperativity, and Physical Stability of Celecoxib Glass	13
Live Cells versus Fixated Cells: Kinetic Measurements of Biomolecular Interactions with the LigandTracer Method and Surface Plasmon Resonance Microscopy	13
Fluorine-18 Labeling of the MDM2 Inhibitor RG7388 for PET Imaging: Chemistry and Preliminary Evaluation	13
Transfer of ANS-Like Drugs from Micellar Drug Delivery Systems to Albumin Is Highly Favorable and Protected from Competition with Surfactant by “Reserved” Binding Sites	13
Preclinical Evaluation of a Companion Diagnostic Radiopharmaceutical, [¹⁸F]PSMA-1007, in a Subcutaneous Prostate Cancer Xenograft Mouse Model	13
Molecular Dynamics Simulation Studies of Bile, Bile Salts, Lipid-Based Drug Formulations, and mRNA–Lipid Nanoparticles: A Review	13
Influence of PLGA End Groups on the Release Profile of Dexamethasone from Ocular Implants	13
Dual-Drug-Loaded Topical Delivery of Photodynamically Active Lipid-Based Formulation for Combination Therapy of Cutaneous Melanoma	13
hucMSC-Derived Exosomes Alleviate the Deterioration of Colitis via the miR-146a/SUMO1 Axis	13
Head-to-Head Comparison of ⁶⁸Ga-PSMA-11 with ⁶⁸Ga-P137 in Patients with Suspected Prostate Cancer	13
Folic Acid-Decorated Nanocrystals as Highly Loaded Trojan Horses to Target Cancer Cells	13
Human Natural Killer Cells Cryopreserved without DMSO Sustain Robust Effector Responses	13
Microemulsion for Prolonged Release of Fenretinide in the Mammary Tissue and Prevention of Breast Cancer Development	13
Pharmaceutical Development Challenges in a Beyond Rule of Five Prodrug: Case Study of ABBV-167, Phosphate Prodrug of Venetoclax	13
Combination of Targeted Therapies for Colorectal Cancer Treatment	13
Machine Learning Models for Mycobacterium tuberculosis In Vitro Activity: Prediction and Target Visualization	13
Polyaspartic Acid-Stabilized CaCO₃-Containing In Situ Hydrogel for Protection and Treatment of Gastric Ulcer	13
Multifunctional Probe Based on “Chemical Antibody–Aptamer” for Noninvasive Detection of PD-L1 Expression in Cancer	13
Biomaterials-Enabled Antithrombotics: Recent Advances and Emerging Strategies	13
Therapeutic Potential of Quercetin-Loaded Nanoemulsion against Experimental Visceral Leishmaniasis: In Vitro/Ex Vivo Studies and Mechanistic Insights	13
In Vitro Predictive Dissolution Test Should Be Developed and Recommended as a Bioequivalence Standard for the Immediate-Release Solid Oral Dosage Forms of the Highly Variable Mycophenolate Mofetil	13
Influence of Pore Size and Surface Functionalization of Mesoporous Silica Nanoparticles on the Solubility and Antioxidant Activity of Confined Coenzyme Q10	13
Modular Platform for the Development of Recombinant Hemoglobin Scavenger Biotherapeutics	13
A Multifunctional Liposome for Synergistic Chemotherapy with Ferroptosis Activation of Triple-Negative Breast Cancer	13
Quantitative Characterization of Clinically Relevant Drug-Metabolizing Enzymes and Transporters in Rat Liver and Intestinal Segments for Applications in PBPK Modeling	13
Issue Publication Information	12
Coupled Discrete Phase and Eulerian Wall Film Models for Drug Deposition Efficacy Analysis in Human Respiratory Airways	12
Issue Editorial Masthead	12
Highly Soluble Dacarbazine Multicomponent Crystals Less Prone to Photodegradation	12
Effective Combination of Targeted Therapies with Sonodynamic Treatment for Use in Exploring Differences in Therapeutic Efficacy across Organelle Targets	12
Concomitant Effect of Quercetin and Its Copper Complex in the Development of Sustained-Release Nanoparticles of Polycaprolactone, Used for the Treatment of Skin Infection	12
Pterostilbene-Loaded Soluplus/Poloxamer 188 Mixed Micelles for Protection against Acetaminophen-Induced Acute Liver Injury	12
A Silk-Based Platform to Stabilize Phenylalanine Ammonia-lyase for Orally Administered Enzyme Replacement Therapy	12
Correlating Differences in the Surface Activity to Interface-Induced Particle Formation in Different Protein Modalities: IgG mAb Versus Fc-Fusion Protein	12
Development and Preclinical Evaluation of ¹⁸F-Labeled PEGylated Sansalvamide A Decapeptide for Noninvasive Evaluation of Hsp90 Status in Pancreas Cancer	12
Self-Interactions of Two Monoclonal Antibodies: Small-Angle X-ray Scattering, Light Scattering, and Coarse-Grained Modeling	12
A Biodistribution Study of the Radiolabeled Kv1.3-Blocking Peptide DOTA-HsTX1[R14A] Demonstrates Brain Uptake in a Mouse Model of Neuroinflammation	12
Optimization of Lipid Nanoparticles for saRNA Expression and Cellular Activation Using a Design-of-Experiment Approach	12
H₂O₂ Self-Supplying and GSH-Depleting Nanocatalyst for Copper Metabolism-Based Synergistic Chemodynamic Therapy and Chemotherapy	12
Minimization of Acid-Catalyzed Degradation in KinetiSol Processing through HPMCAS Neutralization	12
Effect of Data Quality and Data Quantity on the Estimation of Intrinsic Solubility: Analysis Based on a Single-Source Data Set	12
miR-194-Loaded Gelatin Nanospheres Target MEF2C to Suppress Muscle Atrophy in a Mechanical Unloading Model	12
Macrolide and Ketolide Antibiotics Inhibit the Cytotoxic Effect of Trastuzumab Emtansine in HER2-Positive Breast Cancer Cells: Implication of a Potential Drug–ADC Interaction in Cancer Chemotherapy	12
Prof. Raj Suryanarayanan: Honoring His Many Contributions to Molecular Pharmaceutics	12
Difference in Endocytosis Pathways Used by Differentiated Versus Nondifferentiated Epithelial Caco-2 Cells to Internalize Nanosized Particles	12
Solid-State Study of the Structure, Dynamics, and Thermal Processes of Safinamide Mesylate─A New Generation Drug for the Treatment of Neurodegenerative Diseases	12
Linoleic Acid–Glucosamine Hybrid for Endogenous Iron-Activated Ferroptosis Therapy in High-Grade Serous Ovarian Cancer	12