OOIR: Observatory of International Research

Papers

(The TQCC of Clinical Proteomics is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Comparative proteomic analysis of glomerular proteins in primary and bucillamine-induced membranous nephropathy	196
From blood drops to biomarkers: a scoping review of microsampling in mass spectrometry-based proteomics	74
Distinct proteomic profiles of clinical isolates show diversity of Pseudomonas aeruginosa colistin-resistance	54
Changes of serum IgG glycosylation patterns in rheumatoid arthritis	42
Proteome profiling of cutaneous leishmaniasis lesions due to dermotropic Leishmania donovani in Sri Lanka	32
Recent progress in mass spectrometry-based urinary proteomics	32
The relationship between serum astroglial and neuronal markers and AQP4 and MOG autoantibodies	29
CSF levels of brain-derived proteins correlate with brain ventricular volume in cognitively healthy 70-year-olds	27
Quantitative proteomics analysis based on data-independent acquisition reveals the effect of Shenling Baizhu powder (SLP) on protein expression in MAFLD rat liver tissue	27
Quantification of putative ovarian cancer serum protein biomarkers using a multiplexed targeted mass spectrometry assay	26
Correction: Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients	25
Serum proteomics for the identification of biomarkers to flag predilection of COVID19 patients to various organ morbidities	24
Alterations in the pH of pancreatic juice are associated with chymotrypsin C inactivation and lithostathine precipitation in chronic pancreatitis patients: a proteomic approach	22
Mass spectrometry quantifies target engagement for a KRASG12C inhibitor in FFPE tumor tissue	22
Elevated level of multibranched complex glycan reveals an allergic tolerance status	18
An ALS assembly modulator signature in peripheral blood mononuclear cells: implications for ALS pathophysiology, therapeutics, and diagnostics	17
Proteomic profiles screening identified novel exosomal protein biomarkers for diagnosis of lung cancer	17
Plasma exosome proteomics reveals upregulation of CILP-1 in concave side of paraspinal muscle in adolescent idiopathic scoliosis	16
Integrated serum proteomics and metabolomics reveal an INR-associated multi-omics signature in hepatocellular carcinoma	15
Quantitative site-specific N-glycosylation analysis reveals IgG glyco-signatures for pancreatic cancer diagnosis	14
Proteomic characteristics and diagnostic potential of exhaled breath particles in patients with COVID-19	14
Discovery of novel glioma serum biomarkers by proximity extension assay	13
Integrating human plasma proteomes with genome-wide association data implicates novel proteins and drug targets for rheumatoid arthritis	13
Potential biomarker proteins for aspiration pneumonia detected by shotgun proteomics using buccal mucosa samples: a cross-sectional case–control study	13
Nipple aspirate fluid as a proximal breast liquid biopsy platform: advancing precision risk management in breast cancer	13

Proteomic analyses reveal cystatin c is a promising biomarker for evaluation of systemic lupus erythematosus	12
Proteomics study of primary and recurrent adamantinomatous craniopharyngiomas	12
Plasma proteomic characterization of colorectal cancer patients with FOLFOX chemotherapy by integrated proteomics technology	12
Neat plasma proteomics: getting the best out of the worst	12
Plasma proteomic profiling reveals distinct protein signatures associated with hepatocellular carcinoma in chronic hepatitis B infection	12
Plasma proteomics in pediatric patients with sepsis– hopes and challenges	12
Longitudinal serum proteomics identifies inflammatory and metabolic pathways in hypertensive nephrosclerosis progression	12
Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection	11
Proteomic insights into the pathophysiology of hypertension-associated albuminuria: Pilot study in a South African cohort	11
Causal effects and mediation pathways of circulating plasma proteins on osteoporosis: a two-sample and two-step Mendelian randomization study	11
Plasma proteomics of extracellular vesicles identifies key proteins correlating to postoperative atrial fibrillation after coronary artery bypass surgery	11
Characterizing age-related changes in intact mitochondrial proteoforms in murine hearts using quantitative top-down proteomics	10
Recent developments in mass-spectrometry-based targeted proteomics of clinical cancer biomarkers	10
sBioSITe enables sensitive identification of the cell surface proteome through direct enrichment of biotinylated peptides	10
Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response	10
Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients	10
Glial fibrillary acidic protein, neurofilament light, matrix metalloprotease 3 and fatty acid binding protein 4 as non-invasive brain tumor biomarkers	10
Many kinds of oxidized proteins are present more in the urine of the elderly	10
Comparative evaluation of analytical methods for CSF proteomics	10
Quantitative proteomics analysis in small cell carcinoma of cervix reveals novel therapeutic targets	10
The novel biomarkers for assessing clinical benefits of continuous renal replacement therapy in pediatric sepsis: a pilot study	10
Clinic-first sepsis recognition in the ICU: a proteomics-guided, parsimonious model with independent validation	9
Decreased histidine-rich glycoprotein and increased complement C4-B protein levels in follicular fluid predict the IVF outcomes of recurrent spontaneous abortion	9
ARTN and CCL23 predicted chemosensitivity in acute myeloid leukemia: an Olink® proteomics approach	9
Integrating multimodal data to predict the progression of hormone-sensitive prostate cancer	9
Integrating functional proteomics and next generation sequencing reveals potential therapeutic targets for Taiwanese breast cancer	9
Plasma proteomics in septic shock and alcohol-related pancreatitis: a hyaluronan-centered approach	9
Proteome profiling of cerebrospinal fluid-derived extracellular vesicles reveals potential biomarkers for drug-resistant epilepsy	9
Quantitative proteomic analysis of HER2 protein expression in PDAC tumors	9
Validation of the novel GLAS algorithm as an aid in the detection of liver fibrosis and cirrhosis based on GP73, LG2m, age, and sex	9
Calcium-related genes predict prognosis, immune characteristics, and response to immunotherapy in LUAD patients	9
Proteomic and phosphoproteomic signatures of disease progression in unmutated IGHV chronic lymphocytic leukemia	8
SPOT: spatial proteomics through on-site tissue-protein-labeling	8
Medwakh smoking induces alterations in salivary proteins and cytokine expression: a clinical exploratory proteomics investigation	8
Identification of adrenocorticotropic hormone–specific therapeutic biomarkers in infantile epileptic spasm syndrome using data-independent acquisition mass spectrometry	8
Development of a rapid and specific MALDI-TOF mass spectrometric assay for SARS-CoV-2 detection	8
Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization	8
Human tear film protein sampling using soft contact lenses	8
Proteomic analysis of plasma exosomes in patients with metastatic colorectal cancer	8
Novel plasma protein biomarkers from critically ill sepsis patients	8