OOIR: Observatory of International Research

Papers

(The TQCC of Clinical Proteomics is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
From blood drops to biomarkers: a scoping review of microsampling in mass spectrometry-based proteomics	132
Recent progress in mass spectrometry-based urinary proteomics	44
Changes of serum IgG glycosylation patterns in rheumatoid arthritis	40
Comparative proteomic analysis of glomerular proteins in primary and bucillamine-induced membranous nephropathy	28
Proteome profiling of cutaneous leishmaniasis lesions due to dermotropic Leishmania donovani in Sri Lanka	26
The relationship between serum astroglial and neuronal markers and AQP4 and MOG autoantibodies	26
CSF levels of brain-derived proteins correlate with brain ventricular volume in cognitively healthy 70-year-olds	26
Quantitative proteomics analysis based on data-independent acquisition reveals the effect of Shenling Baizhu powder (SLP) on protein expression in MAFLD rat liver tissue	26
Quantification of putative ovarian cancer serum protein biomarkers using a multiplexed targeted mass spectrometry assay	25
Correction: Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients	24
Integrative omics reveals subtle molecular perturbations following ischemic conditioning in a porcine kidney transplant model	24
Data-independent acquisition mass spectrometry in severe rheumatic heart disease (RHD) identifies a proteomic signature showing ongoing inflammation and effectively classifying RHD cases	23
Proteomic alteration of endometrial tissues during secretion in polycystic ovary syndrome may affect endometrial receptivity	20
Serum proteomics for the identification of biomarkers to flag predilection of COVID19 patients to various organ morbidities	20
Plasma exosome proteomics reveals upregulation of CILP-1 in concave side of paraspinal muscle in adolescent idiopathic scoliosis	19
Optimized sample preparation and data analysis for TMT proteomic analysis of cerebrospinal fluid applied to the identification of Alzheimer’s disease biomarkers	19
Mass spectrometry quantifies target engagement for a KRASG12C inhibitor in FFPE tumor tissue	18
An ALS assembly modulator signature in peripheral blood mononuclear cells: implications for ALS pathophysiology, therapeutics, and diagnostics	18
Elevated level of multibranched complex glycan reveals an allergic tolerance status	16
Quantitative site-specific N-glycosylation analysis reveals IgG glyco-signatures for pancreatic cancer diagnosis	16
Discovery of novel glioma serum biomarkers by proximity extension assay	14
Proteomic characteristics and diagnostic potential of exhaled breath particles in patients with COVID-19	14
Alterations in the pH of pancreatic juice are associated with chymotrypsin C inactivation and lithostathine precipitation in chronic pancreatitis patients: a proteomic approach	14
Potential biomarker proteins for aspiration pneumonia detected by shotgun proteomics using buccal mucosa samples: a cross-sectional case–control study	13
Proteomic profiles screening identified novel exosomal protein biomarkers for diagnosis of lung cancer	13

Correction: A SISCAPA-based approach for detection of SARS-CoV-2 viral antigens from clinical samples	12
Plasma proteomics in pediatric patients with sepsis– hopes and challenges	11
Proteomic analyses reveal cystatin c is a promising biomarker for evaluation of systemic lupus erythematosus	11
Neat plasma proteomics: getting the best out of the worst	11
Longitudinal serum proteomics identifies inflammatory and metabolic pathways in hypertensive nephrosclerosis progression	10
Proteomics study of primary and recurrent adamantinomatous craniopharyngiomas	10
Many kinds of oxidized proteins are present more in the urine of the elderly	10
Plasma proteomic characterization of colorectal cancer patients with FOLFOX chemotherapy by integrated proteomics technology	10
Proteomic insights into the pathophysiology of hypertension-associated albuminuria: Pilot study in a South African cohort	10
Glial fibrillary acidic protein, neurofilament light, matrix metalloprotease 3 and fatty acid binding protein 4 as non-invasive brain tumor biomarkers	9
Label-free LC–MS/MS proteomics analyses reveal proteomic changes in oxidative stress and the SOD antioxidant strategy in TM cells	9
Characterizing age-related changes in intact mitochondrial proteoforms in murine hearts using quantitative top-down proteomics	9
The novel biomarkers for assessing clinical benefits of continuous renal replacement therapy in pediatric sepsis: a pilot study	9
Quantitative proteomics analysis in small cell carcinoma of cervix reveals novel therapeutic targets	9
Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response	9
Causal effects and mediation pathways of circulating plasma proteins on osteoporosis: a two-sample and two-step Mendelian randomization study	9
Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection	9
Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients	9
sBioSITe enables sensitive identification of the cell surface proteome through direct enrichment of biotinylated peptides	9
Recent developments in mass-spectrometry-based targeted proteomics of clinical cancer biomarkers	9
Integrating multimodal data to predict the progression of hormone-sensitive prostate cancer	8
Integrating functional proteomics and next generation sequencing reveals potential therapeutic targets for Taiwanese breast cancer	8
SPOT: spatial proteomics through on-site tissue-protein-labeling	8
Quantitative proteomic analysis of HER2 protein expression in PDAC tumors	8
Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization	8
ARTN and CCL23 predicted chemosensitivity in acute myeloid leukemia: an Olink® proteomics approach	8
Validation of the novel GLAS algorithm as an aid in the detection of liver fibrosis and cirrhosis based on GP73, LG2m, age, and sex	8
Decreased histidine-rich glycoprotein and increased complement C4-B protein levels in follicular fluid predict the IVF outcomes of recurrent spontaneous abortion	8
Plasma proteomics in septic shock and alcohol-related pancreatitis: a hyaluronan-centered approach	8
Urinary exosomal RAB11A serves as a novel non-invasive biomarker for diagnosis, treatment response monitoring, and prognosis in small cell lung cancer	7
A novel non-invasive method allowing for discovery of pathologically relevant proteins from small airways	7
Development of a rapid and specific MALDI-TOF mass spectrometric assay for SARS-CoV-2 detection	7
Airway fibrin formation cascade in allergic asthma exacerbation: implications for inflammation and remodeling	7
Novel plasma protein biomarkers from critically ill sepsis patients	7
Glial cell proteome using targeted quantitative methods for potential multi-diagnostic biomarkers	7
Proteomic profiling of extracellular vesicles derived from human serum for the discovery of biomarkers in Avascular necrosis	7
Proteomic analysis of plasma exosomes in patients with metastatic colorectal cancer	7
Human tear film protein sampling using soft contact lenses	7
Quantitative proteomics reveals protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls	7
Quantitative proteomic analysis of serum-purified exosomes identifies putative pre-eclampsia-associated biomarkers	7
Identification of adrenocorticotropic hormone–specific therapeutic biomarkers in infantile epileptic spasm syndrome using data-independent acquisition mass spectrometry	7
Identification of biomarkers of chronic kidney disease among kidney-derived proteins	7
Medwakh smoking induces alterations in salivary proteins and cytokine expression: a clinical exploratory proteomics investigation	7