Clinical Proteomics

Papers
(The TQCC of Clinical Proteomics is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Circulating proteins as predictive and prognostic biomarkers in breast cancer33
Mass spectrometry-based proteomics as an emerging tool in clinical laboratories30
Clinical proteomics for prostate cancer: understanding prostate cancer pathology and protein biomarkers for improved disease management25
The plasma peptides of Alzheimer’s disease23
Proteomic analysis of decidua in patients with recurrent pregnancy loss (RPL) reveals mitochondrial oxidative stress dysfunction20
Tear proteomic profile in three distinct ocular surface diseases: keratoconus, pterygium, and dry eye related to graft-versus-host disease20
Urine proteomics identifies biomarkers for diabetic kidney disease at different stages19
Quantitative proteomics-based analyses performed on pre-eclampsia samples in the 2004–2020 period: a systematic review17
Label-free proteomic analysis of serum exosomes from paroxysmal atrial fibrillation patients17
Mass spectrometry-based proteomics in basic and translational research of SARS-CoV-2 coronavirus and its emerging mutants16
Optimized data-independent acquisition approach for proteomic analysis at single-cell level16
Optimized sample preparation and data analysis for TMT proteomic analysis of cerebrospinal fluid applied to the identification of Alzheimer’s disease biomarkers16
Circulating microvesicles and exosomes in small cell lung cancer by quantitative proteomics16
Variable blood processing procedures contribute to plasma proteomic variability16
Proteomic analysis identifies a signature of disease severity in the plasma of COVID-19 pneumonia patients associated to neutrophil, platelet and complement activation15
Secreted protein markers in oral squamous cell carcinoma (OSCC)14
Rational selection of a biomarker panel targeting unmet clinical needs in kidney injury13
Proteomic and phosphoproteomic measurements enhance ability to predict ex vivo drug response in AML13
Quantitative proteomic analysis of serum-purified exosomes identifies putative pre-eclampsia-associated biomarkers13
A SISCAPA-based approach for detection of SARS-CoV-2 viral antigens from clinical samples12
Evaluation of the potential of Pap test fluid and cervical swabs to serve as clinical diagnostic biospecimens for the detection of ovarian cancer by mass spectrometry-based proteomics12
Data-independent acquisition mass spectrometry in severe rheumatic heart disease (RHD) identifies a proteomic signature showing ongoing inflammation and effectively classifying RHD cases12
Quantitative proteomics analysis of lysine 2-hydroxyisobutyrylation in IgA nephropathy11
Mitochondria and cytochrome components released into the plasma of severe COVID-19 and ICU acute respiratory distress syndrome patients11
Discovery of novel glioma serum biomarkers by proximity extension assay11
Novel plasma protein biomarkers from critically ill sepsis patients10
Proteome profiling of human placenta reveals developmental stage-dependent alterations in protein signature10
Identification of circular RNA BTBD7_hsa_circ_0000563 as a novel biomarker for coronary artery disease and the functional discovery of BTBD7_hsa_circ_0000563 based on peripheral blood mononuclear cell10
Combined proteomic/transcriptomic signature of recurrence post-liver transplantation for hepatocellular carcinoma beyond Milan10
LC-MS/MS based metabolomics and proteomics reveal candidate biomarkers and molecular mechanism of early IgA nephropathy10
Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response10
Integration of transcriptome and proteome profiles in placenta accreta reveals trophoblast over-migration as the underlying pathogenesis9
Global proteome profiling of human livers upon ischemia/reperfusion treatment9
Systematic evaluation and optimization of protein extraction parameters in diagnostic FFPE specimens9
A rigorous evaluation of optimal peptide targets for MS-based clinical diagnostics of Coronavirus Disease 2019 (COVID-19)8
Subclinical effects of remote ischaemic conditioning in human kidney transplants revealed by quantitative proteomics8
An optimized workflow for MS-based quantitative proteomics of challenging clinical bronchoalveolar lavage fluid (BALF) samples7
Recent progress in mass spectrometry-based urinary proteomics7
Analytical validation of a multi-biomarker algorithmic test for prediction of progressive kidney function decline in patients with early-stage kidney disease7
A proteomic profile of the healthy human placenta7
Quantitative proteomics reveals protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls7
A validated analysis pipeline for mass spectrometry-based vitreous proteomics: new insights into proliferative diabetic retinopathy6
Moving translational mass spectrometry imaging towards transparent and reproducible data analyses: a case study of an urothelial cancer cohort analyzed in the Galaxy framework6
Changes of serum IgG glycosylation patterns in rheumatoid arthritis6
Serum proteomics unveil characteristic protein diagnostic biomarkers and signaling pathways in patients with esophageal squamous cell carcinoma6
A novel non-invasive method allowing for discovery of pathologically relevant proteins from small airways6
Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection6
Association between cardiovascular disease- and inflammation-related serum biomarkers and poor lung function in elderly6
Circulating proteins associated with allergy development in infants—an exploratory analysis6
Development of a rapid and specific MALDI-TOF mass spectrometric assay for SARS-CoV-2 detection6
Identification of differentially expressed proteins and clinicopathological significance of HMGB2 in cervical cancer5
Determination of temporal reproducibility and variability of cancer biomarkers in serum and EDTA plasma samples using a proximity extension assay5
Use of MS-GUIDE for identification of protein biomarkers for risk stratification of patients with prostate cancer5
The use of proteomics for blood biomarker research in premature infants: a scoping review5
Neat plasma proteomics: getting the best out of the worst5
Label-free quantitative proteomics reveals aberrant expression levels of LRG, C9, FN, A1AT and AGP1 in the plasma of patients with colorectal cancer5
Quantitative proteomics reveals the effect of Yigu decoction (YGD) on protein expression in bone tissue5
Label-free quantitative proteomic analysis of serum exosomes from patients of renal anemia: The Good and the Bad of Roxadustat5
Redefining serological diagnostics with immunoaffinity proteomics5
O-GlcNAcylation protein disruption by Thiamet G promotes changes on the GBM U87-MG cells secretome molecular signature5
Identification of biomarkers of chronic kidney disease among kidney-derived proteins5
Decreased histidine-rich glycoprotein and increased complement C4-B protein levels in follicular fluid predict the IVF outcomes of recurrent spontaneous abortion5
The novel biomarkers for assessing clinical benefits of continuous renal replacement therapy in pediatric sepsis: a pilot study5
Proteomic analysis identifies dysregulated proteins and associated molecular pathways in a cohort of gallbladder cancer patients of African ancestry5
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