Clinical Proteomics

Papers
(The median citation count of Clinical Proteomics is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Circulating proteins as predictive and prognostic biomarkers in breast cancer33
Mass spectrometry-based proteomics as an emerging tool in clinical laboratories30
Clinical proteomics for prostate cancer: understanding prostate cancer pathology and protein biomarkers for improved disease management25
The plasma peptides of Alzheimer’s disease23
Tear proteomic profile in three distinct ocular surface diseases: keratoconus, pterygium, and dry eye related to graft-versus-host disease20
Proteomic analysis of decidua in patients with recurrent pregnancy loss (RPL) reveals mitochondrial oxidative stress dysfunction20
Urine proteomics identifies biomarkers for diabetic kidney disease at different stages19
Label-free proteomic analysis of serum exosomes from paroxysmal atrial fibrillation patients17
Quantitative proteomics-based analyses performed on pre-eclampsia samples in the 2004–2020 period: a systematic review17
Optimized sample preparation and data analysis for TMT proteomic analysis of cerebrospinal fluid applied to the identification of Alzheimer’s disease biomarkers16
Circulating microvesicles and exosomes in small cell lung cancer by quantitative proteomics16
Variable blood processing procedures contribute to plasma proteomic variability16
Mass spectrometry-based proteomics in basic and translational research of SARS-CoV-2 coronavirus and its emerging mutants16
Optimized data-independent acquisition approach for proteomic analysis at single-cell level16
Proteomic analysis identifies a signature of disease severity in the plasma of COVID-19 pneumonia patients associated to neutrophil, platelet and complement activation15
Secreted protein markers in oral squamous cell carcinoma (OSCC)14
Quantitative proteomic analysis of serum-purified exosomes identifies putative pre-eclampsia-associated biomarkers13
Rational selection of a biomarker panel targeting unmet clinical needs in kidney injury13
Proteomic and phosphoproteomic measurements enhance ability to predict ex vivo drug response in AML13
Data-independent acquisition mass spectrometry in severe rheumatic heart disease (RHD) identifies a proteomic signature showing ongoing inflammation and effectively classifying RHD cases12
A SISCAPA-based approach for detection of SARS-CoV-2 viral antigens from clinical samples12
Evaluation of the potential of Pap test fluid and cervical swabs to serve as clinical diagnostic biospecimens for the detection of ovarian cancer by mass spectrometry-based proteomics12
Discovery of novel glioma serum biomarkers by proximity extension assay11
Quantitative proteomics analysis of lysine 2-hydroxyisobutyrylation in IgA nephropathy11
Mitochondria and cytochrome components released into the plasma of severe COVID-19 and ICU acute respiratory distress syndrome patients11
LC-MS/MS based metabolomics and proteomics reveal candidate biomarkers and molecular mechanism of early IgA nephropathy10
Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response10
Novel plasma protein biomarkers from critically ill sepsis patients10
Proteome profiling of human placenta reveals developmental stage-dependent alterations in protein signature10
Identification of circular RNA BTBD7_hsa_circ_0000563 as a novel biomarker for coronary artery disease and the functional discovery of BTBD7_hsa_circ_0000563 based on peripheral blood mononuclear cell10
Combined proteomic/transcriptomic signature of recurrence post-liver transplantation for hepatocellular carcinoma beyond Milan10
Global proteome profiling of human livers upon ischemia/reperfusion treatment9
Systematic evaluation and optimization of protein extraction parameters in diagnostic FFPE specimens9
Integration of transcriptome and proteome profiles in placenta accreta reveals trophoblast over-migration as the underlying pathogenesis9
A rigorous evaluation of optimal peptide targets for MS-based clinical diagnostics of Coronavirus Disease 2019 (COVID-19)8
Subclinical effects of remote ischaemic conditioning in human kidney transplants revealed by quantitative proteomics8
Analytical validation of a multi-biomarker algorithmic test for prediction of progressive kidney function decline in patients with early-stage kidney disease7
A proteomic profile of the healthy human placenta7
Quantitative proteomics reveals protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls7
An optimized workflow for MS-based quantitative proteomics of challenging clinical bronchoalveolar lavage fluid (BALF) samples7
Recent progress in mass spectrometry-based urinary proteomics7
A novel non-invasive method allowing for discovery of pathologically relevant proteins from small airways6
Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection6
Association between cardiovascular disease- and inflammation-related serum biomarkers and poor lung function in elderly6
Circulating proteins associated with allergy development in infants—an exploratory analysis6
Development of a rapid and specific MALDI-TOF mass spectrometric assay for SARS-CoV-2 detection6
A validated analysis pipeline for mass spectrometry-based vitreous proteomics: new insights into proliferative diabetic retinopathy6
Moving translational mass spectrometry imaging towards transparent and reproducible data analyses: a case study of an urothelial cancer cohort analyzed in the Galaxy framework6
Changes of serum IgG glycosylation patterns in rheumatoid arthritis6
Serum proteomics unveil characteristic protein diagnostic biomarkers and signaling pathways in patients with esophageal squamous cell carcinoma6
O-GlcNAcylation protein disruption by Thiamet G promotes changes on the GBM U87-MG cells secretome molecular signature5
Identification of biomarkers of chronic kidney disease among kidney-derived proteins5
Decreased histidine-rich glycoprotein and increased complement C4-B protein levels in follicular fluid predict the IVF outcomes of recurrent spontaneous abortion5
The novel biomarkers for assessing clinical benefits of continuous renal replacement therapy in pediatric sepsis: a pilot study5
Proteomic analysis identifies dysregulated proteins and associated molecular pathways in a cohort of gallbladder cancer patients of African ancestry5
Identification of differentially expressed proteins and clinicopathological significance of HMGB2 in cervical cancer5
Determination of temporal reproducibility and variability of cancer biomarkers in serum and EDTA plasma samples using a proximity extension assay5
Use of MS-GUIDE for identification of protein biomarkers for risk stratification of patients with prostate cancer5
The use of proteomics for blood biomarker research in premature infants: a scoping review5
Neat plasma proteomics: getting the best out of the worst5
Label-free quantitative proteomics reveals aberrant expression levels of LRG, C9, FN, A1AT and AGP1 in the plasma of patients with colorectal cancer5
Quantitative proteomics reveals the effect of Yigu decoction (YGD) on protein expression in bone tissue5
Label-free quantitative proteomic analysis of serum exosomes from patients of renal anemia: The Good and the Bad of Roxadustat5
Redefining serological diagnostics with immunoaffinity proteomics5
Integrating the serum proteomic and fecal metaproteomic to analyze the impacts of overweight/obesity on IBD: a pilot investigation4
Recent developments in mass-spectrometry-based targeted proteomics of clinical cancer biomarkers4
Proteomic signature associated with chronic kidney disease (CKD) progression identified by data-independent acquisition mass spectrometry4
Comparative proteomics analysis in different stages of urothelial bladder cancer for identification of potential biomarkers: highlighted role for antioxidant activity4
Airway fibrin formation cascade in allergic asthma exacerbation: implications for inflammation and remodeling4
Transcriptome profiling and proteomic validation reveals targets of the androgen receptor signaling in the BT-474 breast cancer cell line4
Uncomplicated Plasmodium vivax malaria: mapping the proteome from circulating platelets4
Combination of automated sample preparation and micro-flow LC–MS for high-throughput plasma proteomics4
Label-free LC–MS/MS proteomics analyses reveal proteomic changes in oxidative stress and the SOD antioxidant strategy in TM cells4
sBioSITe enables sensitive identification of the cell surface proteome through direct enrichment of biotinylated peptides3
Functional and quantitative evaluation of the 20S proteasome in serum and intracellular in145 moroccan patients with hematologic malignancies3
Quantitative proteomics identifies and validates urinary biomarkers of rhabdomyosarcoma in children3
Proteomic insights into the pathophysiology of hypertension-associated albuminuria: Pilot study in a South African cohort3
Potential biomarker proteins for aspiration pneumonia detected by shotgun proteomics using buccal mucosa samples: a cross-sectional case–control study3
Proteomics-based evaluation of the mechanism underlying vascular injury via DNA interstrand crosslinks, glutathione perturbation, mitogen-activated protein kinase, and Wnt and ErbB signaling pathways 3
Comparative analysis of differentially abundant proteins quantified by LC–MS/MS between flash frozen and laser microdissected OCT-embedded breast tumor samples3
Development of a predictive model to distinguish prostate cancer from benign prostatic hyperplasia by integrating serum glycoproteomics and clinical variables3
Robust optimization of SWATH-MS workflow for human blood serum proteome analysis using a quality by design approach3
Proteomic alterations associated with residual disease in neoadjuvant chemotherapy treated ovarian cancer tissues3
The rapid detection of procalcitonin in septic serum using immunoaffinity MALDI chips3
Quantitative proteomics analysis based on data-independent acquisition reveals the effect of Shenling Baizhu powder (SLP) on protein expression in MAFLD rat liver tissue3
Orthogonal proteomics methods warrant the development of Duchenne muscular dystrophy biomarkers3
Comparative proteomic analysis of glomerular proteins in primary and bucillamine-induced membranous nephropathy3
Comparison of in-gel and in-solution proteolysis in the proteome profiling of organ perfusion solutions3
A large-scale targeted proteomics of serum and tissue shows the utility of classifying high grade and low grade meningioma tumors3
Proteomic profiling of end-stage COVID-19 lung biopsies3
Proteomic characteristics and diagnostic potential of exhaled breath particles in patients with COVID-192
iTRAQ-based quantitative proteomic analysis of thoracic aortas from adult rats born to preeclamptic dams2
Proteomics of prostate cancer serum and plasma using low and high throughput approaches2
Validation and update of a multivariable prediction model for the identification and management of patients at risk for hepatocellular carcinoma2
Many kinds of oxidized proteins are present more in the urine of the elderly2
Proteomics-based diagnostic peptide discovery for severe fever with thrombocytopenia syndrome virus in patients2
OmicsOne: associate omics data with phenotypes in one-click2
Proteomic analysis identifies subgroups of patients with active systemic lupus erythematosus2
Cerebrospinal fluid camk2a levels at baseline predict long-term progression in multiple sclerosis2
Mapping three-dimensional intratumor proteomic heterogeneity in uterine serous carcinoma by multiregion microsampling2
Closing the gaps in patient management of dyslipidemia: stepping into cardiovascular precision diagnostics with apolipoprotein profiling2
Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization2
Maternal serum CFHR4 protein as a potential non-invasive marker of ventricular septal defects in offspring: evidence from a comparative proteomics study2
The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals2
Glycoproteomics revealed novel N-glycosylation biomarkers for early diagnosis of lung adenocarcinoma cancers2
Proteomic analyses reveal cystatin c is a promising biomarker for evaluation of systemic lupus erythematosus2
Identification of ORM1, vWF, SPARC, and PPBP as immune-related proteins involved in immune thrombocytopenia by quantitative LC-MS/MS2
Proteomics and functional study reveal kallikrein-6 enhances communicating hydrocephalus2
New mechanisms and biomarkers of lymph node metastasis in cervical cancer: reflections from plasma proteomics2
An LC–MS-based designated comparison method with similar performance to the Lp(a) reference measurement procedure to guide molar Lp(a) standardization2
Proteomics profiles of blood glucose-related proteins involved in a Chinese longevity cohort2
Time dependent effect of cold ischemia on the phosphoproteome and protein kinase activity in fresh-frozen colorectal cancer tissue obtained from patients2
Proteomic alteration of endometrial tissues during secretion in polycystic ovary syndrome may affect endometrial receptivity2
Serum proteomics of severe fever with thrombocytopenia syndrome patients2
13C15N: glucagon-based novel isotope dilution mass spectrometry method for measurement of glucagon metabolism in humans2
Proteome analysis of CD5-positive diffuse large B cell lymphoma FFPE tissue reveals downregulation of DDX3X, DNAJB1, and B cell receptor signaling pathway proteins including BTK and Immunoglobulins2
Proteomic analysis of low- and high-grade human colon adenocarcinoma tissues and tissue-derived primary cell lines reveals unique biological functions of tumours and new protein biomarker candidates2
The associations between red cell distribution width and plasma proteins in a general population2
Investigation on the mechanisms of human sperm DNA damage based on the proteomics analysis by SWATH-MS2
Integration of protein context improves protein-based COVID-19 patient stratification2
Proteomic analysis of sialoliths from calcified, lipid and mixed groups as a source of potential biomarkers of deposit formation in the salivary glands2
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