OOIR: Observatory of International Research

Papers

(The median citation count of Clinical Gastroenterology and Hepatology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Reply	442
Look for a Physical Health Status Surrogate in Hepatocellular Carcinoma: Have we Found the Holy Grail?	334
Simplifying ADR Reporting: A Worthy Goal, but the Devil is in the Details	271
An Unexpected Subepithelial Lesion: Catching the Diagnosis Earlier!	239
Reply	231
Gastric Emphysema With Hepatic Portal Venous Gas Secondary to Acute Gastric Mucosal Lesion	218
Editorial Board	178
Attribution of Colonoscopy Risk Does Not FIT!	174
Exam 1: Treat to Target: The Role of Histologic Healing in Inflammatory Bowel Diseases: A Systematic Review and Meta-analysis	169
Table of Contents	167
Effects of Tenofovir vs Entecavir on Risk of Hepatocellular Carcinoma in Patients With CHB: A Comment for Moving Forward	165
Issue Highlights	164
Elsewhere in the AGA Journals	158
Correction	153
FODMAPs in IBS: Revisiting Restriction	149
Blue Notes	148
Fecal Microbiota Transplantation (FMT) in Ulcerative Colitis: Holding Out for a Superdonor?	146
Ambulatory Acute Kidney Injury in Patients With Cirrhosis Is Common and Burdensome	142
Development of an MRI-Based Prediction Model for Anti-TNF Treatment Failure in Perianal Crohn’s Disease: A Multicenter Study	130
Modified-Release Phosphatidylcholine (LT-02) for Ulcerative Colitis: Two Double-Blind, Randomized, Placebo-Controlled Trials	126
Drug-Related Pneumonitis in Patients Receiving Vedolizumab Therapy for Inflammatory Bowel Disease	125
Low Daily Step Count Is Associated With a High Risk of Hospital Admission and Death in Community-Dwelling Patients With Cirrhosis	124
High Hospitalization Rates and Risk Factors Among Frail Patients With Cirrhosis: A 10-year Population-based Cohort Study	121
Front Cover	118
PErsistence and Safety of Subcutaneous Infliximab 1 Year After Switch From Intravenous Route in IBD Patients in REMission	116

Endoscopic Sleeve Gastroplasty Plus Lifestyle Intervention in Patients With Metabolic Dysfunction-associated Steatohepatitis: A Multicenter, Sham-controlled, Randomized Trial	116
Editorial Board	116
Hepatic Artery Pseudoaneurysm After Whipple Procedure	109
Gut Microbiome Modulation by Antibiotics in Adult Asthma: A Human Proof-of-Concept Intervention Trial	109
Fecal Immunochemical Tests: The Right Colorectal Cancer Screening Test for the Average-Risk Population?	108
An International Multicenter Comparison of IBD-Related Disability and Validation of the IBDDI	108
HBV RNA, Hepatitis B Core-Related Antigen, and Quantitative Hepatitis B Surface Antigen Biomarkers to Predict Outcome of Antiviral Therapy	107
A Case of Pedunculated Esophageal Neuroendocrine Tumor G1	103
Reply	102
Frequent Abnormal Pancreas Imaging in Patients With Pathogenic ATM, BRCA1, BRCA2, and PALB2 Breast Cancer Susceptibility Variants	101
Assessment and Significance of Histologic Activity in Crohn’s Disease	101
Relative Cost-effectiveness of Management Strategies for Uninvestigated Dyspepsia	99
The Evolving Landscape of Colorectal Cancer Screening and Colonoscopy Practice: Insights From the Japan Polyp Study	97
Ileal Pouch Anal Anastomosis for the Management of Ulcerative Colitis Is Associated With Significant Disability	96
Natural History of Patients Lost to Follow-up After Esophageal Food Impaction	95
Disaggregating Racial and Ethnic Data: A Step Toward Diversity, Equity, and Inclusion	93
Health Disparities in Inflammatory Bowel Disease Care Driven by Rural Versus Urban Residence: Challenges and Potential Solutions	93
Barrett’s Esophagus Risk Factors in Patients Without Gastroesophageal Reflux: A Large Population-Based Study	92
A Novel, Noninvasive Method to Diagnose Active Eosinophilic Esophagitis, Combining Clinical Data and Oral Cavity RNA Levels	92
Australasian Insights and Perspectives on the Burden of Chronic Liver Disease	91
Association of Statin Usage and the Development of Diabetes Mellitus after Acute Pancreatitis	89
Editorial Board	89
Endoscopic Polypectomy: How Should We Determine Complete Resection Status?	89
The Diagnostic Performance of Fecal Immunochemical Tests for Detecting Advanced Neoplasia at Surveillance Colonoscopy	88
Overall and Annual Postcolonoscopy Colorectal Cancer Rates in a Large Integrated Healthcare Setting: A Cross-Sectional Study	88
Genetic Diagnosis Guides Treatment of Autoimmune Enteropathy	87
Predictors of Placebo Induction Response and Remission in Ulcerative Colitis	86
Update in the Treatment of the Complications of Cirrhosis	86
AGA Clinical Practice Update on Management of Inflammatory Bowel Disease in Patients With Malignancy: Commentary	85
Sex-Related Differences in the Phenotype and Course of Inflammatory Bowel Disease: SEXEII Study of ENEIDA	85
Elsewhere in the AGA Journals	84
Reply	84
The Impact of the Social Determinants of Health on Disparities in Inflammatory Bowel Disease	84
Long-term Effectiveness and Safety of Risankizumab in Patients With Crohn’s Disease	84
Daily or Twice Daily Treatment With Topical Steroids Results in Similar Responses in Eosinophilic Esophagitis	81
Development of a Simple, Point-of-Care Device to Test Anorectal Function in Patients with Constipation: Randomized Clinical Trial	81
Sugar-Sweetened Beverage, Diet Soda, and Nonalcoholic Fatty Liver Disease Over 6 Years: The Framingham Heart Study	80
Comparative Efficacy of Biologics and Small Molecule in Ulcerative Colitis: A Systematic Review and Network Meta-analysis	75
Effect of five dietary emulsifiers on inflammation, permeability, and the gut microbiome: a placebo-controlled randomized trial.	74
Aseptic Abscess Syndrome With Ulcerative Colitis and Pyoderma Gangrenosum	73
Functional Gastrointestinal Disorders and Associated Health Impairment in Individuals with Celiac Disease	73
Benefits and Harms of Hepatocellular Carcinoma Surveillance in a Prospective Cohort of Patients With Cirrhosis	73
In the Era of Direct-Acting Antivirals, Liver Transplant Delisting Due to Clinical Improvement for Hepatitis C Remains Infrequent	72
Nonalcoholic Fatty Liver Disease Natural History: Role of Mathematical Modeling	72
AGA Clinical Practice Update on New Technology and Innovation for Surveillance and Screening in Barrett’s Esophagus: Expert Review	72
Perianal Disease in Pediatric-onset Crohn’s Disease: Incidence, Disease Course, and Long-term Outcomes	72
Metabolic Signatures of Healthy Lifestyle Patterns and Colorectal Cancer Risk in a European Cohort	71
Characterization of Prevalent, Post-Endoscopy, and Incident Esophageal Cancer in the United States: A Large Retrospective Cohort Study	70
Trends in Etiology-based Mortality From Chronic Liver Disease Before and During COVID-19 Pandemic in the United States	69
Prevalence of Gastric Precursor Lesions in Countries With Differential Gastric Cancer Burden: A Systematic Review and Meta-analysis	68

Low Incidence of Pulmonary Aspiration During Upper Endoscopy in Patients Prescribed a Glucagon-Like Peptide 1 Receptor Agonist	68
Fibrosis-4 Index Predicts Long-Term All-Cause, Cardiovascular and Liver-Related Mortality in the Adult Korean Population	67
Prevalence and Factors Associated With Statin Use Among Patients With Nonalcoholic Fatty Liver Disease in the TARGET-NASH Study	67
Relationship Between Gastric Emptying Rate and Simultaneously Assessed Symptoms in Functional Dyspepsia	66
AGA Clinical Practice Update on Endoscopic Management of Perforations in Gastrointestinal Tract: Expert Review	66
Familial Risk of Inflammatory Bowel Disease: A Population-Based Cohort Study in South Korea	66
National Trends and Waitlist Outcomes of Locoregional Therapy Among Liver Transplant Candidates With Hepatocellular Carcinoma in the United States	66
Effectiveness of Reinduction and/or Dose Escalation of Ustekinumab in Crohn’s Disease: A Systematic Review and Meta-analysis	65
Reply	64
Blue Notes	64
An Approach to the Primary and Secondary Prevention of Gastric Cancer in the United States	64
Extended Risankizumab Treatment in Patients With Crohn’s Disease Who Did Not Achieve Clinical Response to Induction Treatment	64
Information for Authors and Readers	63
Reply	63
Editorial Board	63
Reply	63
Cover	63
Transient Uterine Prolapse: A Rare Complication of Endoscopic Polypectomy	62
Editorial Board	62
Table of Contents	62
Reply	62
Information for Authors and Readers	62
Direct Oral Anticoagulants in Budd-Chiari Syndrome: Need a Closer Look!	62
Editorial Board	61
Von Willebrand Factor Level Indicate Response to β-Blockers in Cirrhosis: Need a Closer Look!	61
Editorial Board	61
Health Policy Priorities for the Biden Administration	61
Cover	61
Multiple Negative Fecal Immunochemical Tests: Is Testing Really Better?	60
Unusual Presentation of a Crohn’s Disease Patient: Not Your Typical Flare	60
Table of Contents	60
Hurdles in ERCP Trials: Do We Need to Change the Diagnostic Criteria for Post-ERCP Pancreatitis?	59
Close Observation of the Lateral Walls of the Oropharynx During Esophagogastroduodenoscopy	58
Environmental Toxins in Breast Milk and Risk of Early Onset Colorectal Cancer	58
Reply	58
Reply	58
Reply	57
Statins for Chronic Liver Disease and the Need for Randomized Controlled Trials	57
Long-Term Proton Pump Inhibitor Use: Review of Indications and Special Considerations	56
Gastroparesis and Chronic Pancreatitis: Are They Truly Related?	56
Foaming at the Varix: Sclerotherapy of Esophageal Varices via Intrahepatic Portal Vein Access	56
Assessing Diagnostic Performance of Modifications to the Rome IV Criteria for Irritable Bowel Syndrome	56
Distinct Clinical Physiologic Phenotypes of Patients With Laryngeal Symptoms Referred for Reflux Evaluation	55
Adenoma Detection Rate (ADR) Irrespective of Indication Is Comparable to Screening ADR: Implications for Quality Monitoring	55
An Unusual Complication of Endoscopic Ultrasound-guided Transgastric Liver Biopsy	55
Population-based Screening for Hereditary Colorectal Cancer Variants in Japan	55
A Randomized, Controlled Trial of Efficacy and Safety of Cannabidiol in Idiopathic and Diabetic Gastroparesis	55
Real-World Surgical and Endoscopic Recurrence Based on Risk Profiles and Prophylaxis Utilization in Postoperative Crohn’s Disease	54
Two vs One Forward View Examination of Right Colon on Adenoma Detection: An International Multicenter Randomized Trial	54
Adenoma Detection Rate and Clinical Characteristics Influence Advanced Neoplasia Risk After Colorectal Polypectomy	53
Prior Authorizations Delay Therapy, Impact Decision-making, and Lead to Adverse Events in Inflammatory Bowel Disease: 2022 Provider Survey	53
Antibody Response Six Months after SARS-CoV-2 mRNA Vaccination in Patients with Inflammatory Bowel Disease	53
The Severity of Reduced Esophageal Distensibility Parallels Eosinophilic Esophagitis Disease Duration	53
The Affordable Care Act Improves Access, Survival, and Racial Disparities of Patients With Liver Disease: A Systematic Review	52
Continuous Risk Score Predicts Waitlist and Post-transplant Outcomes in Hepatocellular Carcinoma Despite Exception Changes	52
Real-world Comparison of Steatosis-Associated Fibrosis Estimator and Fibrosis-4 Scores for Assessing Metabolic Dysfunction-associated Steatotic Liver Disease-related Fibrosis in a Highly Diverse Urban	52
Primary Sclerosing Cholangitis–Associated Pouchitis: A Distinct Clinical Phenotype	52
Deficits in Geriatric Assessment Associate With Disease Activity and Burden in Older Patients With Inflammatory Bowel Disease	52
Needle Track Seeding After Trans-gastric EUS-guided Tissue Sampling: Maybe Not as Rare as You Think	52
Reply	51
A Framework for Creating a FOAMed Organization in Gastroenterology: Lessons Learned from the Liver Fellow Network	51
Extraintestinal Dymptoms in Irritable Bowel Syndrome Are Associated With Stress Reactivity and the Gut Microbiome in a Sex-dependent Manner	51
Comparative Risk of Serious Infections With Biologic Agents and Oral Small Molecules in Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis	50
Birth Cohort Colorectal Cancer (CRC): Implications for Research and Practice	50
Risk of Advanced Colorectal Neoplasia at Follow-up Colonoscopy After Synchronous Adenoma and Clinically Significant Serrated Polyp	50
Colon Volume by Computed Tomography and Scintigraphic Colonic Transit in Constipated Patients With or Without Redundant Colon	50
Continuing the Commitment to Diversity, Equity, and Inclusion Within AGA Journals	50
Correction	49
Front Cover	48
Exploring the Early Phase of Crohn’s Disease	48
Prediction of Relapse After Anti–Tumor Necrosis Factor Cessation in Crohn’s Disease: Individual Participant Data Meta-analysis of 1317 Patients From 14 Studies	47
Distinctive Clinical Correlates of Small Intestinal Bacterial Overgrowth with Methanogens	47
Value of Ammonia Testing in Clinical Practice	47
Development of a Practical Guide to Implement and Monitor Diet Therapy for Eosinophilic Esophagitis	47
Reply	47
The New Kids on the Block: Emerging Complementary Colonoscopy Quality Metrics	47
North American Expert Consensus on the Post-procedural Care of Patients After Per-oral Endoscopic Myotomy Using a Delphi Process	47
Diverticulosis Is Associated With Internal Hemorrhoids on Colonoscopy: Possible Clues to Etiology	47
Perianal Fistulizing Crohn’s Disease–Associated Anorectal and Fistula Cancers: Systematic Review and Expert Consensus	46
Development and Validation of a Noninvasive Model for the Detection of High-Risk Varices in Patients With Unresectable Hepatocellular Carcinoma	46

Upadacitinib in Mothers With Inflammatory Bowel Disease: Placental Transfer and Breast Milk Excretion	45
Weight Change and the Development of Nonalcoholic Fatty Liver Disease in Metabolically Healthy Overweight Individuals	45
Uptake of Colorectal Cancer Screening in 45 to 49 Year Olds: An Early-Inning View from the Endoscopy Suite	45
Response to “Recent Advancements and Future Perspectives of Per Oral Endoscopic Myotomy”	45
Drug-induced Liver Injury in Latin America: 10-year Experience of the Latin American DILI (LATINDILI) Network	45
All-cause and Cause-specific Mortality in Achalasia: A Nationwide Matched Cohort Study	45
Prolonged Gastrointestinal Manifestations After Recovery From COVID-19	45
Significance of Crypt Atypia in Barrett’s Esophagus: A Clinical, Molecular, and Outcome Study	45
Personalized (N-of-1) Clinical Trials for Inflammatory Bowel Disease: Opportunities and Challenges	45
Acute-onset Type 1 Diabetes Mellitus and Pancreatic Atrophy Caused by an Immune Checkpoint Inhibitor	45
Low Colorectal Cancer Risk After Resection of High-Risk Pedunculated Polyps	45
Bouveret Syndrome Treated With Endoscopic Lithotripsy and Gallbladder Access via Cholecysto-duodenal Fistula	45
Harm-to-Benefit Ratio of Fecal Immunochemical Test–Based Screening for Colorectal Cancer Given Prior Fecal Hemoglobin Concentrations	45
Risk of Cancer in Biopsy-Proven Alcohol-Related Liver Disease: A Population-Based Cohort Study of 3410 Persons	44
Diet and Microbiome-Directed Therapy 2.0 for IBD	44
Skills or Pills: Randomized Trial Comparing Hypnotherapy to Medical Treatment in Children With Functional Nausea	44
Constrictive and Hypertrophic Strictures in Ileal Crohn’s Disease	44
Longitudinal Fecal Calprotectin Profiles Characterize Disease Course Heterogeneity in Crohn’s Disease	44
The Role of Resilience in Irritable Bowel Syndrome, Other Chronic Gastrointestinal Conditions, and the General Population	44
The EXTENT Study: Results From an International Expert Delphi Consensus to Define Ultrasonographic Parameters for Measuring Bowel Damage in Crohn’s Disease	43
Genetics of Metabolic Dysfunction-associated Steatotic Liver Disease: The State of the Art Update	43
Metabolic Dysfunction-Associated Steatotic Liver Disease Facilitates Hepatitis B Surface Antigen Seroclearance and Seroconversion	43
Safety and Efficacy of Novel Incretin Co-agonist Cotadutide in Biopsy-proven Noncirrhotic MASH With Fibrosis	43
Preoperative Hepatology and Primary Care Visits Improve Postoperative Outcomes in Patients With Cirrhosis Undergoing Surgery	43
Nonrecurrence Rate of Underwater EMR for ≤20-mm Nonampullary Duodenal Adenomas: A Multicenter Prospective Study (D-UEMR Study)	43
Avoidant Restrictive Food Intake Disorder Prevalent Among Patients With Inflammatory Bowel Disease	43
Clinical Outcomes of Intraductal Papillary Mucinous Neoplasms With Dilatation of the Main Pancreatic Duct	43
Reply	42
Elsewhere in the AGA Journals	42
Biologics for Inflammatory Bowel Disease and Their Safety in Pregnancy: A Systematic Review and Meta-analysis	42
Incidence of and Risk Factors for Colorectal Strictures in Ulcerative Colitis: A Multicenter Study	42
Anti-TL1A Antibody PF-06480605 Safety and Efficacy for Ulcerative Colitis: A Phase 2a Single-Arm Study	42
Estimating Global Prevalence of Metabolic Dysfunction-Associated Fatty Liver Disease in Overweight or Obese Adults	42
Dietary Fiber is Associated With Decreased Risk of Gastroesophageal Reflux Symptoms	41
Reply	41
Reply	41
Table of Contents	41
Stratifying Risks of Ileal Pouch Outcomes	40
Prediction of Postoperative Recurrence in Crohn’s Disease: Where Do We Go From Here?	40
Porcelain Gallbladder	40
Reply	40
Reply	40
To Stop or Not to Stop? Predicting Relapse After Anti-TNF Cessation in Patients With Crohn’s Disease	40
Adult-Onset Fontan Circuit Failure: A Rare Cause of Protein-Losing Enteropathy	40
Bleeding Gastric Teratoma on Adult Patient	40
Reply	40
Lymphangioma in a Child Managed With Debulking Surgery	40
Underestimation of Cirrhosis-Related Mortality in the Medicare Eligible Population, 1999–2018	39
Editorial Board	39
Front Cover	39
Blue Notes	39
Reduction in Racial and Ethnic Disparity in Survival Following Liver Transplant for Hepatocellular Carcinoma in the Direct-acting Antiviral Era	39
Upadacitinib Was Efficacious and Well-tolerated Over 30 Months in Patients With Crohn’s Disease in the CELEST Extension Study	39
Reply	39
Disparities in Colorectal Cancer Screening Among Asian American Populations and Strategies to Address These Disparities	39
Defining Radiological Healing in Perianal Fistulizing Crohn’s Disease: a TOpClass Global Expert Delphi Consensus	39
Information for Authors and Readers	39
Editorial Board	39
Diffuse Large B-Cell Duodenal Lymphoma Presenting With Obstruction and Pneumatosis	38
Ustekinumab and Vedolizumab Safety and Clearance in Pregnancy With Inflammatory Bowel Disease: Stop the Disease, Not the Drug!	38
Preparing the Next Generation of Gastroenterologists to Tackle Climate Change	38
Elsewhere in the AGA Journals	38
Blue Notes	38
Decreasing Case Fatality Rates for Patients With Cirrhosis Infected With SARS-CoV-2: A National COVID Cohort Collaborative Study	38
Editorial Board	38
Reply	37
Real-World Effectiveness of Lenvatinib in Hepatocellular Carcinoma Patients with Nonalcoholic Steatohepatitis	37
Immunomodulator Withdrawal From Anti-TNF Therapy Is Not Associated With Loss of Response in Inflammatory Bowel Disease	37
Nature and Nurture in Familial Aggregation of Steatotic Liver Disease	37
Prevalence of Liver Steatosis and Fibrosis in Adults With Primary Hypobetaliproteinemia: Results From the HYPOCHOL Study	37
Symptom Classes in Decompensated Liver Disease	37
Approach to Dietary Restriction in Irritable Bowel Syndrome	37
Hepatitis B RNA and Core-Related Antigen Provide Value Beyond DNA in Evaluating e But Not Surface Antigen Clearance	37
Endoscopic Submucosal Dissection for Esophageal Squamous Cell Carcinoma With Varices Using Red Dichromatic Imaging	37
Reply	37
Reply	36
A Randomized Phase II Study of Efmarodocokin Alfa, an interleukin-22 Agonist, Versus Vedolizumab in Patients With Ulcerative Colitis	36
Declines in Colorectal Cancer Incidence and Mortality Rates Slow Among Older Adults	36
AGA Clinical Practice Update on Endoscopic Lifting Agents: Commentary	36
Baseline Hepatitis B Virus Surface Antigen Titers in Childhood Predict the Risk of Advanced Liver Fibrosis in Adulthood	36
An Expert Consensus Delphi Panel in Metabolic Dysfunction- and Alcohol-associated Liver Disease: Opportunities and Challenges in Clinical Practice	36
Contemporary Changes in Etiology for Hepatocellular Carcinoma in Liver Transplantation	36
Crafting a Therapeutic Pyramid for Eosinophilic Esophagitis in the Age of Biologics	36
Patterns of Alcohol Use After Early Liver Transplantation for Alcoholic Hepatitis	35
Repeating Ultrasound for Hepatocellular Carcinoma Detection in Case of Inadequate Liver Visualization: A Matter of Expertise	35
Dynamics of Liver Stiffness Measurement and Clinical Course of Primary Biliary Cholangitis	35
Lubiprostone for Pediatric Functional Constipation: Randomized, Controlled, Double-Blind Study With Long-term Extension	35
Depression and Anxiety Are Common Among Patients With Cirrhosis	35
Effect of Exclusion Diets on Symptom Severity and the Gut Microbiota in Patients With Irritable Bowel Syndrome	35
Risk Difference of Liver-Related and Cardiovascular Events by Liver Fibrosis Status in Nonalcoholic Fatty Liver Disease	35
Patient Navigation Increases Linkage to Care and Receipt of Direct-acting Antiviral Therapy in Patients with Hepatitis C	35
Definition and Management of Patients With Primary Biliary Cholangitis and an Incomplete Response to Therapy	35
Letter Response to: Hernandez-Rocha C et al, Clin Gastroenterol Hepatol 2024	35
Efficacy and Acceptability of Dietary Therapies in Non-Constipated Irritable Bowel Syndrome: A Randomized Trial of Traditional Dietary Advice, the Low FODMAP Diet, and the Gluten-Free Diet	35
Comparative Efficacy and Rapidity of Action for Infliximab vs Ustekinumab in Biologic Naïve Crohn’s Disease	34