Ocular Surface

Papers
(The TQCC of Ocular Surface is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
ArticleCitations
ACE2 and TMPRSS2 are expressed on the human ocular surface, suggesting susceptibility to SARS-CoV-2 infection230
The evidence of SARS-CoV-2 infection on ocular surface201
A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells102
Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface100
Prevalence and risk factors of dry eye in 79,866 participants of the population-based Lifelines cohort study in the Netherlands90
Prevalence of SARS-CoV-2 in human post-mortem ocular tissues85
The keratoconus enigma: A review with emphasis on pathogenesis84
Corneal stromal wound healing: Major regulators and therapeutic targets68
Randomised double-masked placebo-controlled trial of the cumulative treatment efficacy profile of intense pulsed light therapy for meibomian gland dysfunction66
Fungal keratitis: A review of clinical presentations, treatment strategies and outcomes59
Assessing the ocular surface microbiome in severe ocular surface diseases58
Single-cell transcriptomics identifies limbal stem cell population and cell types mapping its differentiation trajectory in limbal basal epithelium of human cornea56
The gut-eye-lacrimal gland-microbiome axis in Sjögren Syndrome54
Neurotrophic keratitis: Frequency, etiologies, clinical management and outcomes53
Immune - Goblet cell interaction in the conjunctiva49
Use of digital displays and ocular surface alterations: A review49
Intense pulsed light treatment in meibomian gland dysfunction: A concise review47
Ocular surface microbiota in patients with aqueous tear-deficient dry eye46
The physical and mental burden of dry eye disease: A large population-based study investigating the relationship with health-related quality of life and its determinants46
NLRP12- and NLRC4-mediated corneal epithelial pyroptosis is driven by GSDMD cleavage accompanied by IL-33 processing in dry eye46
Association between dry eye and depressive symptoms: Large-scale crowdsourced research using the DryEyeRhythm iPhone application44
Organoids and organ chips in ophthalmology44
Molecular identity of human limbal heterogeneity involved in corneal homeostasis and privilege43
Long-term outcomes of amniotic membrane treatment in acute Stevens-Johnson syndrome/toxic epidermal necrolysis41
The eye as the discrete but defensible portal of coronavirus infection41
Pigment epithelium-derived factor (PEDF) plays anti-inflammatory roles in the pathogenesis of dry eye disease40
Safety and feasibility of mesenchymal stem cell therapy in patients with aqueous deficient dry eye disease39
Demographic and lifestyle risk factors of dry eye disease subtypes: A cross-sectional study39
Visualization of microneuromas by using in vivo confocal microscopy: An objective biomarker for the diagnosis of neuropathic corneal pain?39
The relationship between dry eye and sleep quality38
Predicting the likelihood of need for future keratoplasty intervention using artificial intelligence37
Tear cytokine levels in the diagnosis and severity assessment of ocular chronic graft-versus-host disease(GVHD)36
Aggregated neutrophil extracellular traps occlude Meibomian glands during ocular surface inflammation36
New insights into the lacrimal pump36
Ageing and the natural history of dry eye disease: A prospective registry-based cross-sectional study34
Ocular manifestations of anti-neoplastic immune checkpoint inhibitor-associated Stevens-Johnson syndrome/toxic epidermal necrolysis in cancer patients32
Impact of the COVID-19 pandemic on eye strain and dry eye symptoms32
Decellularized porcine cornea-derived hydrogels for the regeneration of epithelium and stroma in focal corneal defects31
High-fat diet induces dry eye-like ocular surface damages in murine31
The ocular surface immune system through the eyes of aging31
Correlation of corneal immune cell changes with clinical severity in dry eye disease: An in vivo confocal microscopy study30
Pathophysiology of aniridia-associated keratopathy: Developmental aspects and unanswered questions30
Ocular surface disease associated with dupilumab treatment for atopic diseases30
The molecular basis of neurotrophic keratopathy: Diagnostic and therapeutic implications. A review29
TFOS Lifestyle Report: Impact of environmental conditions on the ocular surface28
Latest evidences on meibomian gland dysfunction diagnosis and management28
Systemic risk factors of dry eye disease subtypes: A New Zealand cross-sectional study28
Interactions of polar lipids with cholesteryl ester multilayers elucidate tear film lipid layer structure27
Alterations in corneal nerves in different subtypes of dry eye disease: An in vivo confocal microscopy study27
Epithelium-derived IL-33 activates mast cells to initiate neutrophil recruitment following corneal injury27
The role of Th17 immunity in chronic ocular surface disorders27
Small fiber neuropathy in the cornea of Covid-19 patients associated with the generation of ocular surface disease27
Relationships between activated dendritic cells and dry eye symptoms and signs26
Management of corneal complications in vernal keratoconjunctivitis: A review26
Eicosapentaenoic acid (EPA) activates PPARγ signaling leading to cell cycle exit, lipid accumulation, and autophagy in human meibomian gland epithelial cells (hMGEC)26
Diagnostic armamentarium of infectious keratitis: A comprehensive review25
Giant papillary conjunctivitis: A review25
Supramolecular host-guest hyaluronic acid hydrogels enhance corneal wound healing through dynamic spatiotemporal effects25
Ocular pain response to treatment in dry eye patients25
Developing evidence-based guidance for the treatment of dry eye disease with artificial tear supplements: A six-month multicentre, double-masked randomised controlled trial25
Ocular surface diabetic disease: A neurogenic condition?24
A phase II randomized trial to evaluate the long-term (12-week) efficacy and safety of OC-01 (varenicline solution) nasal spray for dry eye disease: The MYSTIC study24
Ocular redness – I: Etiology, pathogenesis, and assessment of conjunctival hyperemia24
Melanocytes as emerging key players in niche regulation of limbal epithelial stem cells24
A systematic review of cellular therapies for the treatment of limbal stem cell deficiency affecting one or both eyes23
Dry eye disease in children and adolescents in India23
The vision-related burden of dry eye23
Transcriptomic profiling of human corneal epithelial cells exposed to airborne fine particulate matter (PM2.5)22
Altered ocular surface immune cell profile in patients with dry eye disease22
Dry anophthalmic socket syndrome – Standardized clinical evaluation of symptoms and signs22
Impact of aging on the pathophysiology of dry eye disease: A systematic review and meta-analysis22
Meibomian gland dysfunction is the primary determinant of dry eye symptoms: Analysis of 2346 patients22
Abnormal neovascular and proliferative conjunctival phenotype in limbal stem cell deficiency is associated with altered microRNA and gene expression modulated by PAX6 mutational status in congenital a22
Activation of ocular surface mast cells promotes corneal neovascularization21
Epidemiology, economic and humanistic burdens of Ocular Surface Chemical Injury: A narrative review21
Artificial intelligence in dry eye disease21
Low-dose naltrexone is effective and well-tolerated for modulating symptoms in patients with neuropathic corneal pain21
The epidemiology of infectious keratitis21
A randomized, sham-controlled trial of intraductal meibomian gland probing with or without topical antibiotic/steroid for obstructive meibomian gland dysfunction21
TFOS Lifestyle: Impact of the digital environment on the ocular surface21
Interleukin-4 stimulates lipogenesis in meibocytes by activating the STAT6/PPARγ signaling pathway21
Enhanced closed eye neutrophil degranulation in dry eye disease20
DryEyeRhythm: A reliable and valid smartphone application for the diagnosis assistance of dry eye20
Corneal neurotization for neurotrophic keratopathy: Review of surgical techniques and outcomes20
Comparison of clinical characteristics of post-refractive surgery-related and post-herpetic neuropathic corneal pain20
In-situ porcine corneal matrix hydrogel as ocular surface bandage20
The utility of anterior segment optical coherence tomography angiography for the assessment of limbal stem cell deficiency20
Tissue engineered corneal epithelium derived from clinical-grade human embryonic stem cells20
SARS-CoV-2 receptor ACE2 is expressed in human conjunctival tissue, especially in diseased conjunctival tissue20
Role of optical coherence tomography angiography in the characterization of vascular network patterns of ocular surface squamous neoplasia20
Sex and age differences in symptoms and signs of dry eye disease in a Norwegian cohort of patients19
Membrane-associated mucins of the human ocular surface in health and disease19
Conjunctival transcriptome analysis reveals the overexpression of multiple pattern recognition receptors in vernal keratoconjunctivitis19
Matrix metalloproteinase 9 positivity predicts long term decreased tear production19
Lid margin keratinization in Stevens-Johnson syndrome: Review of pathophysiology and histopathology19
Pigment Epithelium-derived Factor secreted by corneal epithelial cells regulates dendritic cell maturation in dry eye disease19
Relationship between screen time and dry eye symptoms in pediatric population during the COVID-19 pandemic18
Repurposing medications18
Decellularized porcine conjunctiva as an alternative substrate for tissue-engineered epithelialized conjunctiva18
TFOS Lifestyle: Impact of lifestyle challenges on the ocular surface18
Dysfunction of the limbal epithelial stem cell niche in aniridia-associated keratopathy18
Type 1 diabetes mellitus impairs diurnal oscillations in murine extraorbital lacrimal glands17
New insight into lacrimal gland function: Role of the duct epithelium in tear secretion17
The use of in vivo confocal microscopy in fungal keratitis – Progress and challenges17
SARS-CoV-2 and its beta variant of concern infect human conjunctival epithelial cells and induce differential antiviral innate immune response17
Advances in the management of Acanthamoeba keratitis: A review of the literature and synthesized algorithmic approach17
Topical glaucoma medications – Clinical implications for the ocular surface17
Efficacy and tolerability of nortriptyline in the management of neuropathic corneal pain17
Corneal lymphangiogenesis in dry eye disease is regulated by substance P/neurokinin-1 receptor system through controlling expression of vascular endothelial growth factor receptor 316
Alteration in meibum lipid composition and subjective symptoms due to aging and meibomian gland dysfunction16
Retroprosthetic membrane: A complication of keratoprosthesis with broad consequences16
Association of dry eye disease and sun exposure in geographically diverse adult (≥40 years) populations of India: The SEED (sun exposure, environment and dry eye disease) study - Second report of the 16
The role of meibography in ocular surface diagnostics: A review16
Clinical practice patterns in the management of dry eye disease: A TFOS international survey16
Prior inhibition of AKT phosphorylation by BX795 can define a safer strategy to prevent herpes simplex virus-1 infection of the eye16
The role of nitric oxide in ocular surface physiology and pathophysiology15
Human meibum and tear film derived (O-acyl)-omega-hydroxy fatty acids in meibomian gland dysfunction15
TFOS lifestyle: Impact of societal challenges on the ocular surface15
IL-36α/IL-36RA/IL-38 signaling mediates inflammation and barrier disruption in human corneal epithelial cells under hyperosmotic stress15
The link between Keratoconus and posterior segment parameters: An updated, comprehensive review15
Resident plasmacytoid dendritic cells patrol vessels in the naïve limbus and conjunctiva14
Long-term outcomes of cultivated cell sheet transplantation for treating total limbal stem cell deficiency14
Efficacy of cyanoacrylate tissue adhesive in the management of corneal thinning and perforation due to microbial keratitis14
TFOS Lifestyle: Impact of elective medications and procedures on the ocular surface14
TFOS Lifestyle: Impact of cosmetics on the ocular surface14
Safety and efficacy of UV application for superficial infections in humans: A systematic review and meta-analysis14
Relationship between unhealthy sleep status and dry eye symptoms in a Japanese population: The JPHC-NEXT study14
Ocular surface disease in thyroid eye disease: A narrative review14
TFOS Lifestyle: Impact of nutrition on the ocular surface14
The relationship between alcohol consumption and dry eye14
Automated quantification of meibomian gland dropout in infrared meibography using deep learning13
The potential of lipid mediator networks as ocular surface therapeutics and biomarkers13
The effects of systemic cyclosporine in acute Stevens-Johnson syndrome/toxic epidermal necrolysis on ocular disease13
Light cycle phase advance as a model for jet lag reprograms the circadian rhythms of murine extraorbital lacrimal glands13
The impact of anticancer drugs on the ocular surface13
Modulating the tachykinin: Role of substance P and neurokinin receptor expression in ocular surface disorders13
Drug induced cicatrizing conjunctivitis: A case series with review of etiopathogenesis, diagnosis and management13
A reliable animal model of corneal stromal opacity: Development and validation using in vivo imaging13
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