Ocular Surface

Papers
(The TQCC of Ocular Surface is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells121
Prevalence and risk factors of dry eye in 79,866 participants of the population-based Lifelines cohort study in the Netherlands107
Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface107
Prevalence of SARS-CoV-2 in human post-mortem ocular tissues94
Fungal keratitis: A review of clinical presentations, treatment strategies and outcomes85
Corneal stromal wound healing: Major regulators and therapeutic targets85
Single-cell transcriptomics identifies limbal stem cell population and cell types mapping its differentiation trajectory in limbal basal epithelium of human cornea68
The physical and mental burden of dry eye disease: A large population-based study investigating the relationship with health-related quality of life and its determinants58
Ocular surface microbiota in patients with aqueous tear-deficient dry eye53
Use of digital displays and ocular surface alterations: A review51
Molecular identity of human limbal heterogeneity involved in corneal homeostasis and privilege51
Organoids and organ chips in ophthalmology50
Demographic and lifestyle risk factors of dry eye disease subtypes: A cross-sectional study50
Pigment epithelium-derived factor (PEDF) plays anti-inflammatory roles in the pathogenesis of dry eye disease48
The relationship between dry eye and sleep quality45
Safety and feasibility of mesenchymal stem cell therapy in patients with aqueous deficient dry eye disease44
TFOS Lifestyle Report: Impact of environmental conditions on the ocular surface42
The eye as the discrete but defensible portal of coronavirus infection42
Impact of the COVID-19 pandemic on eye strain and dry eye symptoms38
The ocular surface immune system through the eyes of aging38
TFOS Lifestyle: Impact of the digital environment on the ocular surface38
The epidemiology of infectious keratitis37
Aggregated neutrophil extracellular traps occlude Meibomian glands during ocular surface inflammation37
Diagnostic armamentarium of infectious keratitis: A comprehensive review36
The molecular basis of neurotrophic keratopathy: Diagnostic and therapeutic implications. A review35
Pathophysiology of aniridia-associated keratopathy: Developmental aspects and unanswered questions34
Correlation of corneal immune cell changes with clinical severity in dry eye disease: An in vivo confocal microscopy study33
Ocular manifestations of anti-neoplastic immune checkpoint inhibitor-associated Stevens-Johnson syndrome/toxic epidermal necrolysis in cancer patients33
Developing evidence-based guidance for the treatment of dry eye disease with artificial tear supplements: A six-month multicentre, double-masked randomised controlled trial33
Alterations in corneal nerves in different subtypes of dry eye disease: An in vivo confocal microscopy study32
Ocular surface disease associated with dupilumab treatment for atopic diseases31
Supramolecular host-guest hyaluronic acid hydrogels enhance corneal wound healing through dynamic spatiotemporal effects31
Impact of aging on the pathophysiology of dry eye disease: A systematic review and meta-analysis31
Relationships between activated dendritic cells and dry eye symptoms and signs31
Management of corneal complications in vernal keratoconjunctivitis: A review30
The role of Th17 immunity in chronic ocular surface disorders30
Small fiber neuropathy in the cornea of Covid-19 patients associated with the generation of ocular surface disease30
A phase II randomized trial to evaluate the long-term (12-week) efficacy and safety of OC-01 (varenicline solution) nasal spray for dry eye disease: The MYSTIC study29
Ocular redness – I: Etiology, pathogenesis, and assessment of conjunctival hyperemia29
The use of in vivo confocal microscopy in fungal keratitis – Progress and challenges28
Advances in the management of Acanthamoeba keratitis: A review of the literature and synthesized algorithmic approach28
Melanocytes as emerging key players in niche regulation of limbal epithelial stem cells28
TFOS Lifestyle: Impact of lifestyle challenges on the ocular surface28
Altered ocular surface immune cell profile in patients with dry eye disease27
Ocular surface diabetic disease: A neurogenic condition?27
A systematic review of cellular therapies for the treatment of limbal stem cell deficiency affecting one or both eyes27
Membrane-associated mucins of the human ocular surface in health and disease26
The vision-related burden of dry eye26
Artificial intelligence in dry eye disease25
Conjunctival transcriptome analysis reveals the overexpression of multiple pattern recognition receptors in vernal keratoconjunctivitis25
Abnormal neovascular and proliferative conjunctival phenotype in limbal stem cell deficiency is associated with altered microRNA and gene expression modulated by PAX6 mutational status in congenital a25
Epidemiology, economic and humanistic burdens of Ocular Surface Chemical Injury: A narrative review25
Lid margin keratinization in Stevens-Johnson syndrome: Review of pathophysiology and histopathology24
The role of nitric oxide in ocular surface physiology and pathophysiology24
TFOS Lifestyle: Impact of contact lenses on the ocular surface24
Automated quantification of meibomian gland dropout in infrared meibography using deep learning23
In-situ porcine corneal matrix hydrogel as ocular surface bandage23
Clinical practice patterns in the management of dry eye disease: A TFOS international survey23
Corneal neurotization for neurotrophic keratopathy: Review of surgical techniques and outcomes22
TFOS Lifestyle: Impact of societal challenges on the ocular surface22
The utility of anterior segment optical coherence tomography angiography for the assessment of limbal stem cell deficiency22
TFOS Lifestyle: Impact of elective medications and procedures on the ocular surface22
Topical glaucoma medications – Clinical implications for the ocular surface21
Low-dose naltrexone is effective and well-tolerated for modulating symptoms in patients with neuropathic corneal pain21
Repurposing medications21
DryEyeRhythm: A reliable and valid smartphone application for the diagnosis assistance of dry eye21
Matrix metalloproteinase 9 positivity predicts long term decreased tear production21
Sex and age differences in symptoms and signs of dry eye disease in a Norwegian cohort of patients21
TFOS Lifestyle: Impact of nutrition on the ocular surface21
Relationship between screen time and dry eye symptoms in pediatric population during the COVID-19 pandemic20
Dysfunction of the limbal epithelial stem cell niche in aniridia-associated keratopathy20
SARS-CoV-2 and its beta variant of concern infect human conjunctival epithelial cells and induce differential antiviral innate immune response20
SARS-CoV-2 receptor ACE2 is expressed in human conjunctival tissue, especially in diseased conjunctival tissue20
Modulating the tachykinin: Role of substance P and neurokinin receptor expression in ocular surface disorders20
TFOS Lifestyle: Impact of cosmetics on the ocular surface19
Antibiotic treatment for dry eye disease related to meibomian gland dysfunction and blepharitis – A review19
Corneal lymphangiogenesis in dry eye disease is regulated by substance P/neurokinin-1 receptor system through controlling expression of vascular endothelial growth factor receptor 318
Alteration in meibum lipid composition and subjective symptoms due to aging and meibomian gland dysfunction18
Light cycle phase advance as a model for jet lag reprograms the circadian rhythms of murine extraorbital lacrimal glands18
Ocular surface disease associated with immune checkpoint inhibitor therapy18
The link between Keratoconus and posterior segment parameters: An updated, comprehensive review18
Human meibum and tear film derived (O-acyl)-omega-hydroxy fatty acids in meibomian gland dysfunction18
Ocular surface disease in thyroid eye disease: A narrative review17
The relationship between alcohol consumption and dry eye17
IL-36α/IL-36RA/IL-38 signaling mediates inflammation and barrier disruption in human corneal epithelial cells under hyperosmotic stress17
The role of meibography in ocular surface diagnostics: A review17
Biomarkers of in vivo limbal stem cell function15
The effects of systemic cyclosporine in acute Stevens-Johnson syndrome/toxic epidermal necrolysis on ocular disease15
Lacrimal gland regeneration: The unmet challenges and promise for dry eye therapy15
Latest developments in meibography: A review15
Relationship between unhealthy sleep status and dry eye symptoms in a Japanese population: The JPHC-NEXT study15
Meibum sphingolipid composition is altered in individuals with meibomian gland dysfunction-a side by side comparison of Meibum and Tear Sphingolipids15
Spontaneous face- and eye-touching: Infection risk versus potential microbiome gain15
Safety and efficacy of UV application for superficial infections in humans: A systematic review and meta-analysis15
Assessment of response to multimodal management of neurotrophic corneal disease14
The potential of lipid mediator networks as ocular surface therapeutics and biomarkers14
Relationship between eyelid margin irregularity and meibomian gland dropout14
Concurrent ocular pain in patients with neurotrophic keratopathy14
Neuroanatomy and neurochemistry of rat cornea: Changes with age14
A multicenter report of the use of plasma rich in growth factors (PRGF) for the treatment of patients with ocular surface diseases in North America14
Human meibum and tear film derived cholesteryl and wax esters in meibomian gland dysfunction and tear film structure14
Drug induced cicatrizing conjunctivitis: A case series with review of etiopathogenesis, diagnosis and management13
Regulatory role of miR-146a in corneal epithelial wound healing via its inflammatory targets in human diabetic cornea13
Readership awareness series – Paper 4: Chatbots and ChatGPT - Ethical considerations in scientific publications13
A randomized, vehicle-controlled, Phase 2b study of two concentrations of the TRPM8 receptor agonist AR-15512 in the treatment of dry eye disease (COMET-1)13
The conjunctival extracellular matrix, related disorders and development of substrates for conjunctival restoration13
Evaluating the clinical translational relevance of animal models for limbal stem cell deficiency: A systematic review13
Efficacy and outcome of simple limbal epithelial transplantation for limbal stem cell deficiency verified by epithelial phenotypes integrated with clinical evaluation13
Salivary gland transplantation for dry eye disease: Indications, techniques, and outcomes13
Neuronal-epithelial cell alignment: A determinant of health and disease status of the cornea13
Randomized trial of topical periocular castor oil treatment for blepharitis13
Toward electron-beam sterilization of a pre-assembled Boston keratoprosthesis12
MicroRNAs of extracellular vesicles derived from mesenchymal stromal cells alleviate inflammation in dry eye disease by targeting the IRAK1/TAB2/NF-κB pathway12
Medication use and dry eye symptoms: A large, hypothesis-free, population-based study in the Netherlands12
Eyelid blood vessel and meibomian gland changes in a sclerodermatous chronic GVHD mouse model12
The work-related burden of dry eye12
Understanding chronic ocular surface pain: An unmet need for targeted drug therapy12
Dry eye disease and proteomics12
Creation and grading of experimental corneal scars in mice models11
Mesenchymal stromal cells for corneal transplantation: Literature review and suggestions for successful clinical trials11
The Link module of human TSG-6 (Link_TSG6) promotes wound healing, suppresses inflammation and improves glandular function in mouse models of Dry Eye Disease11
TFOS Lifestyle - Evidence quality report: Advancing the evaluation and synthesis of research evidence11
Corneal gene therapy: Structural and mechanistic understanding11
Saturation of cholesteryl esters produced by human meibomian gland epithelial cells after treatment with rosiglitazone11
Meibomian gland dysfunction is suppressed via selective inhibition of immune responses by topical LFA-1/ICAM antagonism with lifitegrast in the allergic eye disease (AED) model11
Herpes simplex virus, varicella-zoster virus and cytomegalovirus keratitis: Facts for the clinician11
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