Ocular Surface

Article	Citations
Human meibomian gland epithelial cell culture models: Current progress, challenges, and future directions	131
Glycosaminoglycans: Roles in wound healing, formation of corneal constructs and synthetic corneas	95
A randomized, vehicle-controlled, Phase 2b study of two concentrations of the TRPM8 receptor agonist AR-15512 in the treatment of dry eye disease (COMET-1)	68
Effects of Panretinal photocoagulation on the ocular surface and tear film	62
Atypical microbial keratitis	54
A phase 2a, double-masked, randomized, vehicle-controlled trial of VVN001 in subjects with dry eye disease	53
Readership awareness series - Paper 5: The peer review process	51
Modified technique for sutureless amniotic membrane transplantation in acute Stevens-Johnson syndrome using fibrin sealant	49
Reply to the letter-to-the-editor: Morphological retinal changes in keratoconus	49
Alleviating experimental allergic eye disease by inhibiting pro-lymphangiogenic VEGFR3 signal	42
Genetic predisposition to ocular surface disorders and opportunities for gene-based therapies	40
Readership awareness series - Paper 1: Ghost authorship	40
Pipeline: Ocular biostatistics: Proper use of proportions	39
Safety and feasibility of subconjunctival injection of mesenchymal stem cells for acute severe ocular burns: A single-arm study	38
The micronucleus cytome assay – A fast tool for DNA damage screening in human conjunctival epithelial cells	38
The prevalence and recurrence risk of bare sclera pterygium surgery in the United States	37
Patients with neurotrophic keratitis demonstrate alterations in ocular surface expression of transient receptor potential (TRP) channels	37
Anterior segment optical coherence tomography angiography in the assessment of ocular surface lesions	37
Artificial intelligence in dry eye disease	35
Managing chronic inflammation in ocular sequelae of Stevens Johnson Syndrome to restore vision	35
Therapeutic efficacy of topical blockade of substance P in experimental allergic red eye	33
Human meibum and tear film derived (O-acyl)-omega-hydroxy fatty acids in meibomian gland dysfunction	32
Saturation of cholesteryl esters produced by human meibomian gland epithelial cells after treatment with rosiglitazone	32
New-onset keratitis associated with epidermal growth factor receptor-based targeted therapies in Han Chinese patients with lung cancer: A multi-center cohort study	31
Comparative analysis of human tear fluid and aqueous humor proteomes	31

TNF is a critical cytokine in age-related dry eye disease	30
Effect of therapeutic UVC on corneal DNA: Safety assessment for potential keratitis treatment	29
Dysfunction of the limbal epithelial stem cell niche in aniridia-associated keratopathy	28
The physical and mental burden of dry eye disease: A large population-based study investigating the relationship with health-related quality of life and its determinants	28
Readership awareness series – Paper 11: Copyright licensing for scientific publications	27
Benzalkonium chloride, a common ophthalmic preservative, compromises rat corneal cold sensitive nerve activity	27
Relationship between unhealthy sleep status and dry eye symptoms in a Japanese population: The JPHC-NEXT study	26
Chemical and thermal ocular burns in the United States: An IRIS registry analysis	26
Dry eye disease and proteomics	25
Dry eye disease sustainability	25
Novel characterization of CXCR4 expressing cells in uninfected and herpes simplex virus-1 infected corneas	25
Aggregated neutrophil extracellular traps occlude Meibomian glands during ocular surface inflammation	25
Pathophysiology of aniridia-associated keratopathy: Developmental aspects and unanswered questions	25
Endogenous TSG-6 modulates corneal inflammation following chemical injury	25
The impact of contact lenses on meibomian gland morphology	24
Anomaly of cornea and ocular adnexa in spinster homolog 2 (Spns2) knockout mice	24
Long term study of topical interferon α-2b eye drops as primary treatment of ocular surface squamous neoplasia	24
Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction: A vehicle-controlled, randomized clinical trial	22
Altered ocular surface immune cell profile in patients with dry eye disease	22
The antipsychotropic drug Duloxetine rescues PAX6 haploinsufficiency of mutant limbal stem cells through inhibition of the MEK/ERK signaling pathway	22
Molecular nature of ocular surface barrier function, diseases that affect it, and its relevance for ocular drug delivery	22
Seeing the unseen: Use of a modified OSDI questionnaire to accurately detect chronic ocular GVHD in a hematology clinic	21
Imbalanced IL-37/TNF-α/CTSS signaling disrupts corneal epithelial barrier in a dry eye model in vitro	21
Induction of meibocyte differentiation by three-dimensional, matrigel culture of immortalized human meibomian gland epithelial cells to form acinar organoids	21
The Link module of human TSG-6 (Link_TSG6) promotes wound healing, suppresses inflammation and improves glandular function in mouse models of Dry Eye Disease	21
Monkeypox and ocular implications in humans	20
Ocular surface disease associated with immune checkpoint inhibitor therapy	20
New trends towards glaucoma treatment: Topical osmoprotective microemulsions loaded with latanoprost	19
Antibiotic treatment for dry eye disease related to meibomian gland dysfunction and blepharitis – A review	19
Automated quantification of meibomian gland dropout in infrared meibography using deep learning	18
Corrigendum to “TFOS lifestyle: Impact of lifestyle challenges on the ocular surface” [Ocul Surf 28 (2023) 262–303]	18
Corrigendum to ‟Non-invasive high-contrast imaging of conjunctival goblet cells for the precision diagnosis of ocular surface diseasesˮ [Ocul Surf 24 (2022) 100–102]	18
Molecular identity of human limbal heterogeneity involved in corneal homeostasis and privilege	18
Corrigendum to “Human precorneal tear film and lipid layer dynamics in meibomian gland dysfunction” [Ocul Surf 21 (2021) 250–256]	18
Impact of aging on the pathophysiology of dry eye disease: A systematic review and meta-analysis	18
The relationship between dry eye and sleep quality	18
Corrigendum to “New insights into lacrimal gland anatomy using 7T MRI and electron microscopy: Relevance for lacrimal gland targeted therapies and bioengineering” [Ocul. Surf. 30 (October 2023) 204–21	18
β-Catenin gain of function mutant in mouse periocular neural crest-derived mesenchymal cells impairs embryonic eyelid morphogenesis and leads to blepharophimosis syndrome in mice	17
Scrambler therapy as a novel treatment for unilateral ocular neuropathic pain	17
New insights into lacrimal gland anatomy using 7T MRI and electron microscopy: Relevance for lacrimal gland targeted therapies and bioengineering	17
Big-bubble DALK: A technique in evolution	17
Blinded by smoke: Wildfire smoke exposure and eye irritation in australian wildland firefighters	16
Development and validation of a method to generate phenol red thread tests	15
Ocular surface squamous neoplasia: Update on genetics, epigenetics and opportunities for targeted therapy	15
BMAL1 deficiency provokes dry mouth and eyes by down-regulating ITPR2/3	15
Pipeline: Pricing for drugs treating dry eye disease	15
Mpox Virus and its ocular surface manifestations	15
Editorial Board	15
Biology and medicine on ocular surface restoration: Advancements and limits of limbal stem cell deficiency treatments	14
A systematic review assessing the quality of patient reported outcome measures in ocular surface disease	14

The effect of botulinum neurotoxin A injections on meibomian glands and dry eye	14
Impact of particulate matter and air pollution on ocular surface disease: A systematic review of preclinical and clinical evidence	14
Unapproved drugs – A fix to an unintended consequence of an FDA policy	13
Editorial Board	13
Editorial Board	13
Editorial Board	13
Editorial Board	13
Immuno Tomography (IT) and Imaging Mass Cytometry (IMC) for constructing spatially resolved, multiplexed 3D IMC data sets	13
Eyelid blood vessel and meibomian gland changes in a sclerodermatous chronic GVHD mouse model	13
Modified Boston Type-II Keratoprosthesis Implantation with Autologous Auricular Cartilage Reinforcement	13
Was Marilyn Monroe myopic and an early adopter of colored contact lenses? A review of the evidence and the early history of colored contact lenses	13
Editorial Board	12
Pipeline: Ocular biostatistics: Which is better: One or two?	12
Fluorescein CorneoGraphy (FCG): Use of a repurposed fluorescein imaging technique to objectively standardize corneal staining	12
Maximal tear secretion evoked by controlled stimulation of corneal sensory nerves in healthy individuals and dry eye subjects	12
Predatory bacteria can reduce Pseudomonas aeruginosa induced corneal perforation and proliferation in a rabbit keratitis model	12
Association between systemic medication use and severity of dry eye signs and symptoms in the DRy eye assessment and management (DREAM) study	11
Corneal acetylcholine regulates sensory nerve activity via nicotinic receptors	11
Alterations in corneal nerves in different subtypes of dry eye disease: An in vivo confocal microscopy study	11
Organotypic culture model of mouse meibomian gland as a screening platform for risk factors related to meibomian gland dysfunction	11
Self-complementary AAV vector therapy for treating corneal cloudiness of mucopolysaccharidosis type VII (MPS VII)	11
Effects of age on lacrimal gland bioactive lipids	11
Herpes simplex virus-1 conjunctival dendrite in an immunosuppressed patient	11
Preliminary experience & rationale of primary allo Simple Limbal Epithelial Transplantation (SLET) following surgical excision of Ocular Surface Tumors	10
Intrastromal versus subconjunctival injection of mesenchymal stem/stromal cells for promoting corneal repair	10
A PEDF peptide mimetic effectively relieves dry eye in a diabetic murine model by restoring corneal nerve, barrier, and lacrimal gland function	10
Surgical management of infectious keratitis	10
Epidemiology, economic and humanistic burdens of Ocular Surface Chemical Injury: A narrative review	10
Fungal keratitis: A review of clinical presentations, treatment strategies and outcomes	10
MicroRNAs of extracellular vesicles derived from mesenchymal stromal cells alleviate inflammation in dry eye disease by targeting the IRAK1/TAB2/NF-κB pathway	10
Spontaneous acinar and ductal regrowth after meibomian gland atrophy induced by deletion of FGFR2 in a mouse model	10
Unique cytokine signature in ocular Stevens-Johnson syndrome non-responders	10
Corneal neurotization for neurotrophic keratopathy: Review of surgical techniques and outcomes	10
TFOS Lifestyle: Impact of the digital environment on the ocular surface	10
The relationship between alcohol consumption and dry eye	10
Allogeneic mesenchymal stem cell therapy for dry eye disease in patients with Sjögren's syndrome: A randomized clinical trial	10
Tear metabolomics highlights new potential biomarkers for differentiating between Sjögren's syndrome and other causes of dry eye	10
Tear film changes in symptomatic versus asymptomatic video display terminal users following computer challenge test	9
Modulating the tachykinin: Role of substance P and neurokinin receptor expression in ocular surface disorders	9
A novel severity scoring system for murine ocular graft versus host disease and its correlation with CD3+ T cells in the cornea	9
The effects of a steam warming eye mask on the ocular surface and mental health	9
Past, present, and prospects in microsporidial keratoconjunctivitis- A review	9
Biological tissues and components, and synthetic substrates for conjunctival cell transplantation	9
Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction over six months of treatment: A Phase 2, vehicle-controlled, randomized extension tria	9
Perfluorohexyloctane in dry eye disease: A systematic review of its efficacy and safety as a novel therapeutic agent	9
The relationship between sedentary behavior and dry eye disease	9
Experimental design considerations for studies of human tear proteins	9
The miR-183/96/182 cluster is a checkpoint for resident immune cells and shapes the cellular landscape of the cornea	9
Dry eye disease and blinking behaviors: A narrative review of methodologies for measuring blink dynamics and inducing blink response	9
Deciphering S1P downregulation and sphingolipid homeostasis disruption in fungal keratitis via multi-omics and MALDI-MSI analysis	9
Editorial Board	9
Impact of glaucoma medications on the ocular surface and how ocular surface disease can influence glaucoma treatment	9
Comparable meibomian gland changes in patients with and without ocular graft-versus-host disease after hematopoietic stem cell transplantation	9
Ocular redness – II: Progress in development of therapeutics for the management of conjunctival hyperemia	9
Preservatives and ocular surface disease: A review	8
Efficacy and outcome of simple limbal epithelial transplantation for limbal stem cell deficiency verified by epithelial phenotypes integrated with clinical evaluation	8
Impaired GSH biosynthesis disrupts eye development, lens morphogenesis and PAX6 function	8
Readership awareness series – Paper 10: Open Access Publishing	8
Tetraspanin CD9-derived peptides inhibit Pseudomonas aeruginosa corneal infection and aid in wound healing of corneal epithelial cells	8
Membrane-associated mucins of the human ocular surface in health and disease	8
New disposable esthesiometer (KeraSenseⓇ) to improve diagnosis and management of neurotrophic keratitis	8
Gene expression changes in conjunctival cells associated with contact lens wear and discomfort	8
Herpes simplex virus, varicella-zoster virus and cytomegalovirus keratitis: Facts for the clinician	8
Corneal gene therapy: Structural and mechanistic understanding	8
Dry eye disease flares: A rapid evidence assessment	8
Chronic inflammation as a proposed risk factor for ocular surface squamous neoplasia	8
In vivo confocal microscopic study of corneal innervation in Sjögren's Syndrome with or without small fiber neuropathy	8
Meibomian gland tortuosity, truncation, and dilation in paediatric dry eye disease: A multi-centre, investigator-masked, cross-sectional study	7
Diagnostic performance and optimal cut-off values for tear film lipid layer grading and thickness in dry eye disease: An investigator-masked, randomised crossover study	7
Pigment epithelium-derived factor (PEDF) plays anti-inflammatory roles in the pathogenesis of dry eye disease	7
Small fiber neuropathy in the cornea of Covid-19 patients associated with the generation of ocular surface disease	7
Effects of meibomian gland dysfunction and aqueous deficiency on friction-related disease	7
A large hypothesis-free proteomics study investigating serum inflammatory markers as biomarkers of dry eye disease	7
Simple limbal epithelial transplantation versus cultivated limbal epithelial transplantation in ocular burns	7
Epidemiology and risk factors for the development of cicatrizing conjunctivitis in chronic ocular graft-versus-host disease	7
Manufacturing of human corneal endothelial grafts	7
Impact of digital screen use and lifestyle factors on dry eye disease in the paediatric population	7
Understanding chronic ocular surface pain: An unmet need for targeted drug therapy	7
Letter to the editor regarding “TFOS Lifestyle: Impact of the digital environment on the ocular surface”	7
Meibomian gland lipid alterations and ocular surface sequela in Awat2 knockout murine model of meibomian gland dysfunction and evaporative dry eye disease	7

Topical anti-glaucoma medications effects on meibomian glands: Systematic review and meta-analysis	7
The clinical outcomes of minor salivary gland transplantation for severe dry eye disease secondary to chronic Stevens-Johnson syndrome	7
The roles of neural adaptation and sensitization in contact lens discomfort	7
A multicenter report of the use of plasma rich in growth factors (PRGF) for the treatment of patients with ocular surface diseases in North America	7
A closer look into the cellular and molecular biology of myoepithelial cells across various exocrine glands	7
The epidemiology of infectious keratitis	7
Single-cell RNA-sequencing reveals the transcriptional landscape of lacrimal gland in GVHD mouse model	6
Corneal nerve changes following treatment with neurotoxic anticancer drugs	6
Allergic contact dermatitis of the eyelids: An interdisciplinary review	6
Expression of Acyl-CoA wax-alcohol acyltransferase 2 (AWAT2) by human and rabbit meibomian glands and meibocytes	6
Readership awareness series – Paper 9: Retraction of a publication	6
TFOS Lifestyle Report: Impact of environmental conditions on the ocular surface	6
Lid margin keratinization in Stevens-Johnson syndrome: Review of pathophysiology and histopathology	6
Reconsidering the pathogenesis of chalazion	6
Optimising subjective grading of corneal staining in Sjögren's syndrome dry eye disease	6
Secreted Ly-6/uPAR-related protein-1 (SLURP1) is a pro-differentiation factor that stalls G1-S transition during corneal epithelial cell cycle progression	6
The pattern of the inferocentral whorl region of the corneal subbasal nerve plexus is altered with age	6
A systematic review of cellular therapies for the treatment of limbal stem cell deficiency affecting one or both eyes	6
Low-dose naltrexone is effective and well-tolerated for modulating symptoms in patients with neuropathic corneal pain	6
5-Fluorouracil in primary, impending recurrent and recurrent pterygium: Systematic review of the efficacy and safety of a surgical adjuvant and intralesional antimetabolite	6
Ultrastructural study of the lacrimal glands in severe dry eye disease following Stevens-Johnson syndrome	6
TFOS Lifestyle: Impact of nutrition on the ocular surface	6
A cocktail of small molecules maintains the stemness and differentiation potential of conjunctival epithelial cells	6
Ocular involvement in Clarkson Disease	5
A practical framework for telemedicine in dry eye disease	5
Topical application of cannabinoid-ligands ameliorates experimental dry-eye disease	5
Urgent unmet needs in the care of bacterial keratitis: An evidence-based synthesis	5
Urea and ocular surface: Synthesis, secretion and its role in tear film homeostasis	5
Clinical trials submissions to The Ocular Surface	5
Contact lens-induced corneal parainflammation involving Ly6G+ cell infiltration requires IL-17A and γδ T cells	5
Evaluation of the impact of intensive care support for COVID-19 on the ocular surface in a prospective cohort of 40 eyes	5
Longitudinal analysis of variation in status and diagnostic stability of untreated dry eye disease	5
Morphological retinal changes in keratoconus	5
Optical coherence tomography angiography in the evaluation of vascular patterns of ocular surface squamous neoplasia during topical medical treatment	5
Cyclosporine A 1mg/ml in pediatric blepharokeratoconjunctivitis: Case series of 145 children and young people	5
Automated identification and quantification of activated dendritic cells in central cornea using artificial intelligence	5
Neurotrophic keratopathy associated with cancer immunotherapy targeting programmed death 1	5
Human tear fluid modulates the Pseudomonas aeruginosa transcriptome to alter antibiotic susceptibility	5
TFOS: Unique challenges and unmet needs for the management of ocular surface diseases throughout the world	5
TFOS Lifestyle Report Introduction: A Lifestyle Epidemic - Ocular Surface Disease	5
Investigating the diagnostic utility of non-invasive tear film stability and breakup parameters: A prospective diagnostic accuracy study	5
Calculating efficacy of new ophthalmic treatments. The new calculus	5
Epithelial-mesenchymal transition in the lacrimal gland morphogenesis, damage and repair	5
The gene therapy for corneal pathology with novel nonsense cystinosis mouse lines created by CRISPR Gene Editing	5
Omega-3 polyunsaturated fatty acids and corneal nerve health: Current evidence and future directions	5
A new option for treatment of severe cicatricial entropion in patients with Stevens-Johnson syndrome	5
In situ metabolic profile and spatial distribution of ocular tissues: New insights into dry eye disease	4
Safety and efficacy of UV application for superficial infections in humans: A systematic review and meta-analysis	4
Cellular senescence promotes meibomian gland dysfunction in a chronic graft-versus-host disease mouse model	4
Editorial Board	4
Immune signaling in rosacea	4
Neuroanatomy and neurochemistry of rat cornea: Changes with age	4
Bibliometric analysis of the meibomian gland literature	4
Relationship between dry eye symptoms after cataract surgery and psychiatric status	4
Readership awareness series – Paper 7: An overview of impact factor and other scientometrics	4
The epidemiology of pediatric dry eye disease in the United States: An IRIS® registry (Intelligent Research in Sight) analysis	4
Management of scleral melt	4
Alteration in meibum lipid composition and subjective symptoms due to aging and meibomian gland dysfunction	4
Profile of tear lipid mediator as a biomarker of inflammation for meibomian gland dysfunction and ocular surface diseases: Standard operating procedures	4
Heritability of tear fluid cytokines in healthy twins	4
Metabolic signatures of tear extracellular vesicles caused by herpes simplex keratitis	4
Pipeline: Decoding the package insert: Adverse events revisited	4
Toxicity and efficacy of type I interferons on the ocular surface: in vitro, animal, and clinical studies	3
Corrigendum to “Topical formulations of aprepitant are safe and effective in relieving pain and inflammation, and drive neural regeneration” [Ocul Surf 30 (2023) 92–103]	3
Adipose-derived mesenchymal stromal cells: A study on safety and efficacy in ocular inflammation	3
Prevalence of dry eye disease among Hong Kong aquatic athletes before and after COVID-19: An exploratory study	3
Limiting plastic waste in dry eye practice for environmental sustainability	3
Restoration of corneal epithelial barrier function: A possible target for corneal neovascularization	3
Chronic ocular complications in lamotrigine vs. trimethoprim-sulfamethoxazole induced Stevens-Johnson syndrome/toxic epidermal necrolysis	3
Punctal cautery in dry eye disease: A systematic review	3
Readership awareness series – Paper 12: Clinician-scientist – Threats to the endangered species and preservation strategies	3
Filamentary keratitis: A review	3
Delayed diagnosis of ocular graft-versus-host disease after allogeneic hematopoietic stem cell transplantation	3
Dry eye disease in the young: A narrative review	3
Readership awareness series – Paper 4: Chatbots and ChatGPT - Ethical considerations in scientific publications	3
Detection of SARS-CoV-2 binding receptors and miscellaneous targets as well as mucosal surface area of the human lacrimal drainage system	3
Pipeline: Wiley Chambers, MD, FDA Ophthalmology regulator	3
Dry eye disease adverse reaction of pharmacological treatment for early-stage breast cancer	3
Duloxetine enhances PAX6 expression and suppresses innate immune responses in murine LPS-induced corneal inflammation	3
Demographic and lifestyle risk factors of dry eye disease subtypes: A cross-sectional study	3
Entry receptor bias in evolutionarily distant HSV-1 clinical strains drives divergent ocular and nervous system pathologies	3
The link between Keratoconus and posterior segment parameters: An updated, comprehensive review	3