Ocular Surface

Papers
(The median citation count of Ocular Surface is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Corrigendum to “New insights into lacrimal gland anatomy using 7T MRI and electron microscopy: Relevance for lacrimal gland targeted therapies and bioengineering” [Ocul. Surf. 30 (October 2023) 204–21149
Editorial Board100
Long term study of topical interferon α-2b eye drops as primary treatment of ocular surface squamous neoplasia80
Biology and medicine on ocular surface restoration: Advancements and limits of limbal stem cell deficiency treatments77
Atypical microbial keratitis63
Effects of Panretinal photocoagulation on the ocular surface and tear film61
Endogenous TSG-6 modulates corneal inflammation following chemical injury58
Economic burden of keratitis patients with inpatient care: a nationwide, multicenter registry study56
Safety of subconjunctival injection of mesenchymal stromal cells in persistent corneal epithelial disease – A phase 1b clinical trial53
Development and validation of a method to generate phenol red thread tests51
Monkeypox and ocular implications in humans47
Dry eye disease and proteomics44
Epidemiology and risk factors for the development of cicatrizing conjunctivitis in chronic ocular graft-versus-host disease43
Readership awareness series – Paper 10: Open Access Publishing43
A prospective self-controlled study on the alterations of the ocular surface and conjunctival transcriptomic profile associated with prolonged exposure to video display terminals43
Effects of age on lacrimal gland bioactive lipids42
Predatory bacteria can reduce Pseudomonas aeruginosa induced corneal perforation and proliferation in a rabbit keratitis model42
Tear film changes in symptomatic versus asymptomatic video display terminal users following computer challenge test40
Impact of digital screen use and lifestyle factors on dry eye disease in the paediatric population40
Chronic inflammation as a proposed risk factor for ocular surface squamous neoplasia40
Organotypic culture model of mouse meibomian gland as a screening platform for risk factors related to meibomian gland dysfunction38
Editorial Board38
Herpes simplex virus, varicella-zoster virus and cytomegalovirus keratitis: Facts for the clinician37
A pilot randomized controlled trial of topical androgen treatment in dry eye36
Allogeneic mesenchymal stem cell therapy for dry eye disease in patients with Sjögren's syndrome: A randomized clinical trial36
New disposable esthesiometer (KeraSenseⓇ) to improve diagnosis and management of neurotrophic keratitis34
The clinical outcomes of minor salivary gland transplantation for severe dry eye disease secondary to chronic Stevens-Johnson syndrome33
Diagnostic performance and optimal cut-off values for tear film lipid layer grading and thickness in dry eye disease: An investigator-masked, randomised crossover study32
Corneal gene therapy: Structural and mechanistic understanding31
Modulating the tachykinin: Role of substance P and neurokinin receptor expression in ocular surface disorders31
Interdisciplinary management of belantamab mafodotin-associated ocular toxicity in clinical practice30
Topical low-dose heparin in ocular Stevens Johnson Syndrome and associated molecular correlations: A randomized controlled pilot study29
Profile of tear lipid mediator as a biomarker of inflammation for meibomian gland dysfunction and ocular surface diseases: Standard operating procedures26
Limiting plastic waste in dry eye practice for environmental sustainability26
Toxicity and efficacy of type I interferons on the ocular surface: in vitro, animal, and clinical studies26
Alteration in meibum lipid composition and subjective symptoms due to aging and meibomian gland dysfunction26
TFOS Lifestyle: Impact of nutrition on the ocular surface25
Cyclosporine A 1mg/ml in pediatric blepharokeratoconjunctivitis: Case series of 145 children and young people25
Reconsidering the pathogenesis of chalazion25
5-Fluorouracil in primary, impending recurrent and recurrent pterygium: Systematic review of the efficacy and safety of a surgical adjuvant and intralesional antimetabolite24
A practical framework for telemedicine in dry eye disease24
Investigating the diagnostic utility of non-invasive tear film stability and breakup parameters: A prospective diagnostic accuracy study24
TFOS Lifestyle Report: Impact of environmental conditions on the ocular surface23
Trustworthy research presentations23
Effect of cosmetics on the measurement of the tear lipid layer thickness by LipiView®22
Readership awareness series – Paper 3: Paper mills22
Keratoneuropathy22
Host-microbe interactions in cornea22
Insights into the clinical development of regenerative medical products through a comparison of three cell-based products recently approved for limbal stem cell deficiency21
Corneal nerve regeneration is affected by scar location in herpes simplex keratitis: A longitudinal in vivo confocal microscopy study21
Expert consensus on pediatric dry eye: Insights from a European Delphi study21
Subconjunctival triamcinolone injection for infectious necrotizing scleritis21
1,5-Dicaffeoylquinic acid from Pseudognaphalium affine ameliorates dry eye disease via suppression of inflammation and protection of the ocular surface21
Redefining ocular drug delivery20
Rational design and synthesis of lumican stapled peptides for promoting corneal wound healing20
Exposure keratopathy in patients undergoing invasive ventilation: Prevalence, severity, and the role of surface lubrication19
Lacrimal gland regeneration: The unmet challenges and promise for dry eye therapy19
Label-free quantitative imaging of conjunctival goblet cells19
The evolution of the modified osteo-odonto-keratoprosthesis, its reliability, and long-term visual rehabilitation prognosis: An analytical review18
Conjunctival vessel density analysis as a marker of inflammation in dry eye disease18
Re: Significant errors in the paper by Ballesteros-Sánchez A, Rocha-de-Lossada C and Sánchez-González J. Efficacy of eyelid warming devices as first-step treatment in meibomian gland dysfunction: A sy18
Ocular pain in ocular graft-versus-host disease patients with neurotrophic keratopathy18
Intralesional triamcinolone injection as an adjuvant therapy for refractory cicatrizing conjunctivitis18
Evaluating the clinical translational relevance of animal models for limbal stem cell deficiency: A systematic review18
A novel artificial intelligence model for diagnosing Acanthamoeba keratitis through confocal microscopy18
Readership awareness series - Paper 6: How to write a good peer review report?18
Drug induced cicatrizing conjunctivitis: A case series with review of etiopathogenesis, diagnosis and management17
Smad4 deficiency ameliorates the progressive corneal stroma thinning caused by the loss of Tbr117
Transglutaminase-2 is critical for corneal epithelial barrier function via positive regulation of Claudin-117
Identifying patient-valued outcomes for use in early phase trials of ocular surface disease interventions17
Two models of the structures of the lamellae in human meibum and the tear film lipid layer, TFLL17
Use of a transgenic mouse model for in vivo monitoring of corneal pathologies following Sulfur Mustard Exposure17
Changes in conjunctival mononuclear phagocytes and suppressive activity of regulatory macrophages in desiccation induced dry eye17
Corneal sensory nerve regulation of tear production through stimulation of transient receptor potential melastatin 8 (TRPM8) channel: A potential new approach for treating dry eye disease16
Corrigendum to “Models for Meibomian gland dysfunction: In vivo and in vitro”, Review article [Ocul. Surf. 32 (2024) 154–165]16
Deep learning-based classification of fungal and Acanthamoeba keratitis using confocal microscopy16
Non-invasive high-contrast imaging of conjunctival goblet cells for the precision diagnosis of ocular surface diseases15
Evaluation of ocular neuropathic pain15
Report on the 2021 Aniridia North America symposium on PAX6, aniridia, and beyond15
Optimising the method for visualising mouse meibomian gland using eyelid whole-mount lipid staining15
Autologous serum tears improve corneal nerve density and sensitivity in patients with ocular graft-versus-host disease-associated dry eye disease15
Fenofibrate ameliorates ocular surface inflammation in diabetic keratopathy15
Phenotypic characterization of patients developing chronic dry eye and pain after refractive surgery: A cross-sectional study15
Visual outcomes of children undergoing penetrating keratoplasty in the US15
Morphological characteristics of Meibomian Glands and their Influence on Dry Eye disease in contact lens wearers15
Ocular surface squamous neoplasia: Update on genetics, epigenetics and opportunities for targeted therapy14
Readership awareness series – Paper 11: Copyright licensing for scientific publications14
Downregulation of the core circadian gene Nr1d2 in the lacrimal gland contributes to postoperative dry eye disease by impairing lipid metabolism14
Essential roles of sensory nerve in maintenance of cornea-phenotype in mice14
Ocular graft-versus-host disease: Experience, incidence, and treatment outcomes at a university-based tertiary care ophthalmology center14
High expression of SARS-CoV2 viral entry-related proteins in human limbal stem cells14
Hyperosmotic stress-induced NLRP3 inflammasome activation via the mechanosensitive PIEZO1 channel in dry eye corneal epithelium13
Benzalkonium chloride, a common ophthalmic preservative, compromises rat corneal cold sensitive nerve activity13
Corrigendum to “TFOS lifestyle: Impact of lifestyle challenges on the ocular surface” [Ocul Surf 28 (2023) 262–303]13
A randomized, vehicle-controlled, Phase 2b study of two concentrations of the TRPM8 receptor agonist AR-15512 in the treatment of dry eye disease (COMET-1)13
Pipeline: Ocular biostatistics: Proper use of proportions13
Readership awareness series - Paper 1: Ghost authorship13
BMAL1 deficiency provokes dry mouth and eyes by down-regulating ITPR2/313
The effect of botulinum neurotoxin A injections on meibomian glands and dry eye13
Modified technique for sutureless amniotic membrane transplantation in acute Stevens-Johnson syndrome using fibrin sealant13
Impact of particulate matter and air pollution on ocular surface disease: A systematic review of preclinical and clinical evidence13
Exploration of imaging and molecular biomarkers for differentiation of neuropathic corneal pain from dry eye syndrome13
Novel characterization of CXCR4 expressing cells in uninfected and herpes simplex virus-1 infected corneas12
IVCM image analysis for limbal stem cell deficiency: quantitative diagnostics of the corneal epithelium post-transplant recovery12
Spontaneous acinar and ductal regrowth after meibomian gland atrophy induced by deletion of FGFR2 in a mouse model12
Cellular senescence promotes meibomian gland dysfunction in a chronic graft-versus-host disease mouse model12
Response to “Methodological considerations regarding 'Ranking the efficacy of topical treatments for ocular allergy: A network meta-analysis of current evidence'”12
Pipeline: US FDA efficacy requirements for treatment of ocular surface disease: Drugs vs. medical devices12
In vivo confocal microscopic study of corneal innervation in Sjögren's Syndrome with or without small fiber neuropathy12
Association between systemic medication use and severity of dry eye signs and symptoms in the DRy eye assessment and management (DREAM) study12
Pipeline: Therapeutics – Two views of off-label use12
Tetraspanin CD9-derived peptides inhibit Pseudomonas aeruginosa corneal infection and aid in wound healing of corneal epithelial cells12
Development and optimization of an ex vivo model of corneal epithelium damage with 1-heptanol: Investigating the influence of donor clinical parameters and MSC-sEV treatment on healing capacity12
Preservatives and ocular surface disease: A review12
Mechanoreceptor Piezo1 channel-mediated interleukin expression in conjunctival epithelial cells: Linking mechanical stress to ocular inflammation11
Epithelial-mesenchymal transition in the lacrimal gland morphogenesis, damage and repair11
Duloxetine enhances PAX6 expression and suppresses innate immune responses in murine LPS-induced corneal inflammation11
Adipose-derived mesenchymal stromal cells: A study on safety and efficacy in ocular inflammation11
Pard3 promotes corneal epithelial stratification and homeostasis by regulating apical-basal polarity, cytoskeletal organization and tight junction-mediated barrier function11
Secreted Ly-6/uPAR-related protein-1 (SLURP1) is a pro-differentiation factor that stalls G1-S transition during corneal epithelial cell cycle progression10
Editorial Board10
Glycoprotein 340 expression in hyperosmolar stress and infection of corneal epithelial cells10
Topical steroids to the superior bulbar conjunctiva for the treatment of superior limbic keratoconjunctivitis (SLK)10
Endoplasmic reticulum stress contributes to the development of ocular graft-vs-host disease in the eyelids and the ocular surface10
Readership awareness series – Paper 7: An overview of impact factor and other scientometrics10
Remission of corneal and peripheral neuropathy after bariatric surgery in people with diabetes10
Impact of botulinum toxin type A on ocular pain with neuropathic features10
Characterization of the thickness of the Tear Film Lipid Layer in Meibomian Gland Dysfunction using high resolution optical microscopy10
Restoration of corneal epithelial barrier function: A possible target for corneal neovascularization10
A novel Schirmer strip-based tear matrix metalloproteinase measurement in dry eye evaluation10
Editorial Board10
A prospective, longitudinal study to assess progression of ocular surface signs, tear cytokines and protein profiles in young adults10
Multicenter prospective validation study for international chronic ocular graft-versus-host disease consensus diagnostic criteria10
Editorial Board10
Letter to the editor regarding “TFOS Lifestyle: Impact of the digital environment on the ocular surface”10
The genus decision: Potential impact on ophthalmic pharmaceuticals9
Cytarabine chemotherapy induces meibomian gland dysfunction9
Readership awareness series – paper 14: The submission Dilemma - How to choose a journal?9
Alleviative effect of probiotics and prebiotics on dry eye in type 2 diabetic mice through the gut-eye axis9
The multifaceted aspects of ocular allergies: Phenotypes and endotypes9
Decoding the corneal immune microenvironment in healthy and diabetic mice during corneal wound healing9
Pediatric vs Adult Stevens Johnson Syndrome/Toxic Epidermal Necrolysis: Ocular Outcomes and the Role of Amniotic Membrane9
Topical glaucoma medications – Clinical implications for the ocular surface9
Outcomes of keratolimbal allograft from ABO compatible donors for severe bilateral limbal stem cell deficiency9
Tear lymphotoxin-alpha deficiency is associated with conjunctival epitheliopathy in patients with dry eye disease9
Topical formulations of Aprepitant are safe and effective in relieving pain and inflammation, and drive neural regeneration9
TFOS Lifestyle Report Executive Summary: A Lifestyle Epidemic - Ocular Surface Disease9
High fat diet induced gut dysbiosis alters corneal epithelial injury response in mice8
Anti-inflammatory and wound healing potential of medicinal maggot excretions/secretions at the ocular surface8
Ocular involvement in Mycoplasma induced rash and mucositis: A systematic review of the literature8
Ectoine protects corneal epithelial survival and barrier from hyperosmotic stress by promoting anti-inflammatory cytokine IL-378
Editorial Board8
The conjunctival extracellular matrix, related disorders and development of substrates for conjunctival restoration8
Salivary gland transplantation for dry eye disease: Indications, techniques, and outcomes8
Conditional deletion of CD25 in the corneal epithelium reveals sex differences in barrier disruption8
The corneal fibroblast: The Dr. Jekyll underappreciated overseer of the responses to stromal injury8
Diagnostic armamentarium of infectious keratitis: A comprehensive review8
Density and distribution of dendritiform cells in the peripheral cornea of healthy subjects using in vivo confocal microscopy8
Readership awareness series – Paper 8: Research ethics and ‘editorial expressions of concern’8
Ocular surface disease in thyroid eye disease: A narrative review8
Relationships between ocular surface sphingomyelinases, Meibum and Tear Sphingolipids, and clinical parameters of meibomian gland dysfunction8
Letter to the Editor regarding “Corneal sensory nerve regulation of tear production through stimulation of transient receptor potential melastatin 8 (TRPM8) channel: A potential new approach for treat8
Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction: A vehicle-controlled, randomized clinical trial7
Electroencephalogram-detected stress levels in the frontal lobe region of patients with dry eye7
Blinded by smoke: Wildfire smoke exposure and eye irritation in australian wildland firefighters7
Dry eye disease sustainability7
The antipsychotropic drug Duloxetine rescues PAX6 haploinsufficiency of mutant limbal stem cells through inhibition of the MEK/ERK signaling pathway7
Readership awareness series - Paper 5: The peer review process7
Diagnostic capacity for fungal keratitis in Africa – Survey in 50 African countries7
Destructive and protective effects and therapeutic targets of IL-36 family cytokines in dry eye disease7
Unique cytokine signature in ocular Stevens-Johnson syndrome non-responders7
The impact of contact lenses on meibomian gland morphology7
Herpes simplex virus-1 conjunctival dendrite in an immunosuppressed patient7
The effect of a biweekly novel selenium sulfide-containing topical treatment in symptomatic contact lens wearers: An exploratory study7
Clinical and Genetic Profiling of Fibromyalgia-Associated Dry Eye: A Multifactorial Approach7
Editorial Board7
Patients with neurotrophic keratitis demonstrate alterations in ocular surface expression of transient receptor potential (TRP) channels7
Imbalanced IL-37/TNF-α/CTSS signaling disrupts corneal epithelial barrier in a dry eye model in vitro7
Impact of glaucoma medications on the ocular surface and how ocular surface disease can influence glaucoma treatment6
A multicenter report of the use of plasma rich in growth factors (PRGF) for the treatment of patients with ocular surface diseases in North America6
Epidemiological insights into Childhood vernal keratoconjunctivitis in India: Unravelling clinical presentation and environmental influences – The EPIC VKC study – Fourth report of the ICMR EYE SEE st6
A tribute to Gary N. Foulks, M.D. (1944–2025) and his contributions to the ocular surface6
Delayed diagnosis of ocular graft-versus-host disease after allogeneic hematopoietic stem cell transplantation6
Comparable meibomian gland changes in patients with and without ocular graft-versus-host disease after hematopoietic stem cell transplantation6
A large hypothesis-free proteomics study investigating serum inflammatory markers as biomarkers of dry eye disease6
Prospective consecutive case series of patients with neurotrophic keratopathy associated with unilateral total limbal stem cell deficiency caused by severe ocular surface burns6
Effects of meibomian gland dysfunction and aqueous deficiency on friction-related disease6
The miR-183/96/182 cluster is a checkpoint for resident immune cells and shapes the cellular landscape of the cornea6
Omega-3 polyunsaturated fatty acids and corneal nerve health: Current evidence and future directions6
Detection of SARS-CoV-2 binding receptors and miscellaneous targets as well as mucosal surface area of the human lacrimal drainage system6
Small fiber neuropathy in the cornea of Covid-19 patients associated with the generation of ocular surface disease6
MicroRNAs in corneal Diseases: Emerging roles as biomarkers, regulators, and therapeutics6
A novel severity scoring system for murine ocular graft versus host disease and its correlation with CD3+ T cells in the cornea6
Fluorescein CorneoGraphy (FCG): Use of a repurposed fluorescein imaging technique to objectively standardize corneal staining6
Differences in pre-surgical baseline tear proteome are associated with persistent post-refractive surgery pain6
Self-complementary AAV vector therapy for treating corneal cloudiness of mucopolysaccharidosis type VII (MPS VII)6
Management of scleral melt6
Clinical trials submissions to The Ocular Surface6
TFOS Lifestyle: Impact of the digital environment on the ocular surface6
Identification of a translatable animal model for dry eye disease using comparative analysis of tear proteins across species6
Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction over six months of treatment: A Phase 2, vehicle-controlled, randomized extension tria6
A masked study to differentiate in vivo confocal microscopic features of Pythium insidiosum and fungal filaments6
Readership awareness series – Paper 4: Chatbots and ChatGPT - Ethical considerations in scientific publications5
Antibiotic resistance of Pseudomonas aeruginosa from ocular samples in Canada: a 25-year analysis5
Topical pharmacologic treatments for dry eye disease: A systematic review5
The Yin and Yang of non-immune and immune responses in meibomian gland dysfunction5
A single institute validation study comparing the international chronic ocular graft-versus-host disease consensus group diagnostic criteria with clinical parameters5
Neurotrophic Keratitis: A rare disease that requires proactive screening and orphan drug treatments5
Matrix glycosaminoglycans and proteoglycans in human cornea organoids and similarities with fetal corneal stages5
Novel discovery of a lymphatic bridge connecting Schlemm's canal to limbal and conjunctival lymphatic pathway5
Metabolic signatures of tear extracellular vesicles caused by herpes simplex keratitis5
TFOS Lifestyle Report Introduction: A Lifestyle Epidemic - Ocular Surface Disease5
A review of the epithelial and stromal effects of corneal collagen crosslinking5
Prevalence and antimicrobial susceptibility pattern of coagulase-negative Staphylococci isolated from ocular infections: A systematic review and meta-analysis5
Short chain fatty acids inhibit corneal inflammatory responses to TLR ligands via the ocular G-protein coupled receptor 435
Transitory alkali exposure on meibomian gland orifices induces meibomian gland dysfunction5
The power of the adverb5
Meibomian gland stem/progenitor cells: The hunt for gland renewal5
Dry eye disease in the young: A narrative review5
Pipeline: Patient, physician and developer view of drugs vs. devices5
Preclinical confirmation of UVC efficacy in treating infectious keratitis5
Readership awareness series – Paper 9: Retraction of a publication5
Editorial Board5
Culture- and non-culture-based approaches reveal unique features of the ocular microbiome in dry eye patients5
Detecting dry eye from ocular surface videos based on deep learning5
Ultrasonography assessments of meibomian gland as a noninvasive method of detecting changes in morphology5
Moxifloxacin-resistant and moxifloxacin-susceptible Staphylococcus aureus Keratitis: Outcomes from a 10-year retrospective study5
Trends in using mesenchymal stromal/stem cells (MSCs) in treating corneal diseases4
Tissue-targeted and localized AAV5-DCN and AAV5-PEDF combination gene therapy abrogates corneal fibrosis and concurrent neovascularization in rabbit eyes in vivo4
The use of in vivo confocal microscopy in fungal keratitis – Progress and challenges4
Cicatricial entropion in eyes with lid margin mucous membrane grafting4
Differential homing of monocytes and neutrophils in the epithelial layer of HSV-1 infected cornea regulates viral dissemination and wound healing4
The prevalence and recurrence risk of bare sclera pterygium surgery in the United States4
Human meibomian gland epithelial cell culture models: Current progress, challenges, and future directions4
Methodological considerations regarding "Ranking the efficacy of topical treatments for ocular allergy: A network meta-analysis of current evidence" [Letter]4
Calcium-sensing receptor (CaSR) modulates ocular surface chloride transport and its inhibition promotes ocular surface hydration4
The ocular surface tear film as a biomarker for systemic health4
Topical 1% 5-fluorouracil eye drops as primary treatment for ocular surface squamous neoplasia: Long-term follow-up study4
Combined therapy of ocular surface disease with plasma rich in growth factors and scleral contact lenses4
Pipeline: Pricing for drugs treating dry eye disease4
Seeing the unseen: Use of a modified OSDI questionnaire to accurately detect chronic ocular GVHD in a hematology clinic4
The Link module of human TSG-6 (Link_TSG6) promotes wound healing, suppresses inflammation and improves glandular function in mouse models of Dry Eye Disease4
Heightened visual light sensitivity discomfort measured by the ocular photosensitivity analyzer is associated with chronic ocular pain4
Gene expression signatures in conjunctival fornix aspirates of patients with dry eye disease associated with Meibomian gland dysfunction. A proof-of-concept study4
Peripheral hypertrophic subepithelial corneal degeneration versus Salzmann's nodular degeneration: A clinical and surgical comparison4
New insights into lacrimal gland anatomy using 7T MRI and electron microscopy: Relevance for lacrimal gland targeted therapies and bioengineering4
Managing chronic inflammation in ocular sequelae of Stevens Johnson Syndrome to restore vision4
Antibiotic treatment for dry eye disease related to meibomian gland dysfunction and blepharitis – A review4
Glycosaminoglycans: Roles in wound healing, formation of corneal constructs and synthetic corneas4
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