Ocular Surface

Papers
(The median citation count of Ocular Surface is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Effects of Panretinal photocoagulation on the ocular surface and tear film135
Development and validation of a method to generate phenol red thread tests88
Editorial Board71
Corrigendum to “New insights into lacrimal gland anatomy using 7T MRI and electron microscopy: Relevance for lacrimal gland targeted therapies and bioengineering” [Ocul. Surf. 30 (October 2023) 204–2170
Atypical microbial keratitis58
Monkeypox and ocular implications in humans55
Long term study of topical interferon α-2b eye drops as primary treatment of ocular surface squamous neoplasia52
Endogenous TSG-6 modulates corneal inflammation following chemical injury52
Dry eye disease and proteomics50
Biology and medicine on ocular surface restoration: Advancements and limits of limbal stem cell deficiency treatments47
Editorial Board44
Effects of age on lacrimal gland bioactive lipids43
Impact of digital screen use and lifestyle factors on dry eye disease in the paediatric population42
Corneal gene therapy: Structural and mechanistic understanding42
Epidemiology and risk factors for the development of cicatrizing conjunctivitis in chronic ocular graft-versus-host disease41
A prospective self-controlled study on the alterations of the ocular surface and conjunctival transcriptomic profile associated with prolonged exposure to video display terminals40
Predatory bacteria can reduce Pseudomonas aeruginosa induced corneal perforation and proliferation in a rabbit keratitis model39
Diagnostic performance and optimal cut-off values for tear film lipid layer grading and thickness in dry eye disease: An investigator-masked, randomised crossover study39
New disposable esthesiometer (KeraSenseⓇ) to improve diagnosis and management of neurotrophic keratitis38
Organotypic culture model of mouse meibomian gland as a screening platform for risk factors related to meibomian gland dysfunction37
Herpes simplex virus, varicella-zoster virus and cytomegalovirus keratitis: Facts for the clinician36
Readership awareness series – Paper 10: Open Access Publishing36
The clinical outcomes of minor salivary gland transplantation for severe dry eye disease secondary to chronic Stevens-Johnson syndrome34
Tear film changes in symptomatic versus asymptomatic video display terminal users following computer challenge test34
Chronic inflammation as a proposed risk factor for ocular surface squamous neoplasia33
Allogeneic mesenchymal stem cell therapy for dry eye disease in patients with Sjögren's syndrome: A randomized clinical trial33
Modulating the tachykinin: Role of substance P and neurokinin receptor expression in ocular surface disorders32
A practical framework for telemedicine in dry eye disease31
Cyclosporine A 1mg/ml in pediatric blepharokeratoconjunctivitis: Case series of 145 children and young people31
Investigating the diagnostic utility of non-invasive tear film stability and breakup parameters: A prospective diagnostic accuracy study30
Limiting plastic waste in dry eye practice for environmental sustainability29
Reconsidering the pathogenesis of chalazion29
Profile of tear lipid mediator as a biomarker of inflammation for meibomian gland dysfunction and ocular surface diseases: Standard operating procedures29
Toxicity and efficacy of type I interferons on the ocular surface: in vitro, animal, and clinical studies29
TFOS: Unique challenges and unmet needs for the management of ocular surface diseases throughout the world29
Alteration in meibum lipid composition and subjective symptoms due to aging and meibomian gland dysfunction28
Topical low-dose heparin in ocular Stevens Johnson Syndrome and associated molecular correlations: A randomized controlled pilot study26
TFOS Lifestyle Report: Impact of environmental conditions on the ocular surface26
5-Fluorouracil in primary, impending recurrent and recurrent pterygium: Systematic review of the efficacy and safety of a surgical adjuvant and intralesional antimetabolite26
Effect of cosmetics on the measurement of the tear lipid layer thickness by LipiView®24
The pattern of the inferocentral whorl region of the corneal subbasal nerve plexus is altered with age24
Subconjunctival triamcinolone injection for infectious necrotizing scleritis24
TFOS Lifestyle: Impact of nutrition on the ocular surface24
Exposure keratopathy in patients undergoing invasive ventilation: Prevalence, severity, and the role of surface lubrication23
Keratoneuropathy23
Trustworthy research presentations23
Expert consensus on pediatric dry eye: Insights from a European Delphi study22
Compounded medications for ocular surface disease22
Evaluating the clinical translational relevance of animal models for limbal stem cell deficiency: A systematic review22
Lacrimal gland regeneration: The unmet challenges and promise for dry eye therapy22
Host-microbe interactions in cornea21
Label-free quantitative imaging of conjunctival goblet cells20
Corneal nerve regeneration is affected by scar location in herpes simplex keratitis: A longitudinal in vivo confocal microscopy study20
1,5-Dicaffeoylquinic acid from Pseudognaphalium affine ameliorates dry eye disease via suppression of inflammation and protection of the ocular surface20
Rational design and synthesis of lumican stapled peptides for promoting corneal wound healing20
Clinical study of laminar resorption: Part 2- outcomes, review and proposal for classification20
Readership awareness series – Paper 3: Paper mills20
Redefining ocular drug delivery20
Relationship between screen time and dry eye symptoms in pediatric population during the COVID-19 pandemic19
Re: Significant errors in the paper by Ballesteros-Sánchez A, Rocha-de-Lossada C and Sánchez-González J. Efficacy of eyelid warming devices as first-step treatment in meibomian gland dysfunction: A sy19
The evolution of the modified osteo-odonto-keratoprosthesis, its reliability, and long-term visual rehabilitation prognosis: An analytical review19
Readership awareness series - Paper 6: How to write a good peer review report?19
Insights into the clinical development of regenerative medical products through a comparison of three cell-based products recently approved for limbal stem cell deficiency19
A novel artificial intelligence model for diagnosing Acanthamoeba keratitis through confocal microscopy19
Changes in conjunctival mononuclear phagocytes and suppressive activity of regulatory macrophages in desiccation induced dry eye18
Conjunctival vessel density analysis as a marker of inflammation in dry eye disease18
Ocular pain in ocular graft-versus-host disease patients with neurotrophic keratopathy18
Intralesional triamcinolone injection as an adjuvant therapy for refractory cicatrizing conjunctivitis18
Autologous serum tears improve corneal nerve density and sensitivity in patients with ocular graft-versus-host disease-associated dry eye disease17
Morphological characteristics of Meibomian Glands and their Influence on Dry Eye disease in contact lens wearers17
Report on the 2021 Aniridia North America symposium on PAX6, aniridia, and beyond17
Use of a transgenic mouse model for in vivo monitoring of corneal pathologies following Sulfur Mustard Exposure17
Optimising the method for isolating ocular surface microRNA using impression cytology17
Visual outcomes of children undergoing penetrating keratoplasty in the US17
High expression of SARS-CoV2 viral entry-related proteins in human limbal stem cells16
Transglutaminase-2 is critical for corneal epithelial barrier function via positive regulation of Claudin-116
Non-invasive high-contrast imaging of conjunctival goblet cells for the precision diagnosis of ocular surface diseases16
Smad4 deficiency ameliorates the progressive corneal stroma thinning caused by the loss of Tbr116
Evaluation of ocular neuropathic pain16
Optimising the method for visualising mouse meibomian gland using eyelid whole-mount lipid staining15
Essential roles of sensory nerve in maintenance of cornea-phenotype in mice15
Identifying patient-valued outcomes for use in early phase trials of ocular surface disease interventions15
IL-36α/IL-36RA/IL-38 signaling mediates inflammation and barrier disruption in human corneal epithelial cells under hyperosmotic stress15
Pipeline: Ocular biostatistics: Proper use of proportions15
Phenotypic characterization of patients developing chronic dry eye and pain after refractive surgery: A cross-sectional study15
Ocular graft-versus-host disease: Experience, incidence, and treatment outcomes at a university-based tertiary care ophthalmology center15
Drug induced cicatrizing conjunctivitis: A case series with review of etiopathogenesis, diagnosis and management15
Readership awareness series – Paper 11: Copyright licensing for scientific publications14
Modified technique for sutureless amniotic membrane transplantation in acute Stevens-Johnson syndrome using fibrin sealant14
A randomized, vehicle-controlled, Phase 2b study of two concentrations of the TRPM8 receptor agonist AR-15512 in the treatment of dry eye disease (COMET-1)14
Corrigendum to “TFOS lifestyle: Impact of lifestyle challenges on the ocular surface” [Ocul Surf 28 (2023) 262–303]14
The effect of botulinum neurotoxin A injections on meibomian glands and dry eye14
Impact of particulate matter and air pollution on ocular surface disease: A systematic review of preclinical and clinical evidence14
Novel characterization of CXCR4 expressing cells in uninfected and herpes simplex virus-1 infected corneas14
Readership awareness series - Paper 1: Ghost authorship14
Ocular surface squamous neoplasia: Update on genetics, epigenetics and opportunities for targeted therapy14
BMAL1 deficiency provokes dry mouth and eyes by down-regulating ITPR2/313
Benzalkonium chloride, a common ophthalmic preservative, compromises rat corneal cold sensitive nerve activity13
Development and optimization of an ex vivo model of corneal epithelium damage with 1-heptanol: Investigating the influence of donor clinical parameters and MSC-sEV treatment on healing capacity13
Downregulation of the Core Circadian Gene Nr1d2 in the Lacrimal Gland Contributes to Postoperative Dry Eye Disease by Impairing Lipid Metabolism13
Safety and feasibility of subconjunctival injection of mesenchymal stem cells for acute severe ocular burns: A single-arm study13
Hyperosmotic stress-induced NLRP3 inflammasome activation via the mechanosensitive PIEZO1 channel in dry eye corneal epithelium13
Anterior segment optical coherence tomography angiography in the assessment of ocular surface lesions13
Tetraspanin CD9-derived peptides inhibit Pseudomonas aeruginosa corneal infection and aid in wound healing of corneal epithelial cells12
Pipeline: Therapeutics – Two views of off-label use12
Association between systemic medication use and severity of dry eye signs and symptoms in the DRy eye assessment and management (DREAM) study12
Secreted Ly-6/uPAR-related protein-1 (SLURP1) is a pro-differentiation factor that stalls G1-S transition during corneal epithelial cell cycle progression12
Spontaneous acinar and ductal regrowth after meibomian gland atrophy induced by deletion of FGFR2 in a mouse model12
Biological tissues and components, and synthetic substrates for conjunctival cell transplantation12
Tear metabolomics highlights new potential biomarkers for differentiating between Sjögren's syndrome and other causes of dry eye12
Letter to the editor regarding “TFOS Lifestyle: Impact of the digital environment on the ocular surface”12
In vivo confocal microscopic study of corneal innervation in Sjögren's Syndrome with or without small fiber neuropathy12
Pipeline: US FDA efficacy requirements for treatment of ocular surface disease: Drugs vs. medical devices12
Editorial Board12
Preservatives and ocular surface disease: A review12
Mechanoreceptor Piezo1 channel-mediated interleukin expression in conjunctival epithelial cells: Linking mechanical stress to ocular inflammation11
Endoplasmic reticulum stress contributes to the development of ocular graft-vs-host disease in the eyelids and the ocular surface11
Pard3 promotes corneal epithelial stratification and homeostasis by regulating apical-basal polarity, cytoskeletal organization and tight junction-mediated barrier function11
A novel Schirmer strip-based tear matrix metalloproteinase measurement in dry eye evaluation11
Readership awareness series – Paper 7: An overview of impact factor and other scientometrics11
Adipose-derived mesenchymal stromal cells: A study on safety and efficacy in ocular inflammation11
Restoration of corneal epithelial barrier function: A possible target for corneal neovascularization11
Immune signaling in rosacea11
Epithelial-mesenchymal transition in the lacrimal gland morphogenesis, damage and repair11
Cellular senescence promotes meibomian gland dysfunction in a chronic graft-versus-host disease mouse model11
Duloxetine enhances PAX6 expression and suppresses innate immune responses in murine LPS-induced corneal inflammation11
Remission of corneal and peripheral neuropathy after bariatric surgery in people with diabetes10
Impact of botulinum toxin type A on ocular pain with neuropathic features10
Glycoprotein 340 expression in hyperosmolar stress and infection of corneal epithelial cells10
Cytarabine chemotherapy induces meibomian gland dysfunction10
Alleviative effect of probiotics and prebiotics on dry eye in type 2 diabetic mice through the gut-eye axis10
Characterization of the thickness of the Tear Film Lipid Layer in Meibomian Gland Dysfunction using high resolution optical microscopy10
Decoding the corneal immune microenvironment in healthy and diabetic mice during corneal wound healing10
Editorial Board10
The genus decision: Potential impact on ophthalmic pharmaceuticals10
Topical steroids to the superior bulbar conjunctiva for the treatment of superior limbic keratoconjunctivitis (SLK)10
Topical formulations of Aprepitant are safe and effective in relieving pain and inflammation, and drive neural regeneration10
Editorial Board10
Outcomes of keratolimbal allograft from ABO compatible donors for severe bilateral limbal stem cell deficiency10
The multifaceted aspects of ocular allergies: Phenotypes and endotypes9
Pollen shells and soluble factors play non-redundant roles in the development of allergic conjunctivitis in mice9
Topical glaucoma medications – Clinical implications for the ocular surface9
High fat diet induced gut dysbiosis alters corneal epithelial injury response in mice9
Medication use and dry eye symptoms: A large, hypothesis-free, population-based study in the Netherlands9
Readership awareness series – paper 14: The submission Dilemma - How to choose a journal?9
Readership awareness series – Paper 8: Research ethics and ‘editorial expressions of concern’9
TFOS Lifestyle Report Executive Summary: A Lifestyle Epidemic - Ocular Surface Disease9
Ocular surface disease in thyroid eye disease: A narrative review9
Multicenter prospective validation study for international chronic ocular graft-versus-host disease consensus diagnostic criteria9
A prospective, longitudinal study to assess progression of ocular surface signs, tear cytokines and protein profiles in young adults9
Conditional deletion of CD25 in the corneal epithelium reveals sex differences in barrier disruption9
Density and distribution of dendritiform cells in the peripheral cornea of healthy subjects using in vivo confocal microscopy9
Review, analysis, and education of antiseptic related ocular injury in the surgical settings8
Electroencephalogram-detected stress levels in the frontal lobe region of patients with dry eye8
Ectoine protects corneal epithelial survival and barrier from hyperosmotic stress by promoting anti-inflammatory cytokine IL-378
The corneal fibroblast: The Dr. Jekyll underappreciated overseer of the responses to stromal injury8
Dry eye disease sustainability8
Salivary gland transplantation for dry eye disease: Indications, techniques, and outcomes8
Ocular involvement in Mycoplasma induced rash and mucositis: A systematic review of the literature8
Relationships between ocular surface sphingomyelinases, Meibum and Tear Sphingolipids, and clinical parameters of meibomian gland dysfunction8
Diagnostic armamentarium of infectious keratitis: A comprehensive review8
Editorial Board8
Anti-inflammatory and wound healing potential of medicinal maggot excretions/secretions at the ocular surface8
Editorial Board8
Diagnostic capacity for fungal keratitis in Africa – Survey in 50 African countries8
The effect of a biweekly novel selenium sulfide-containing topical treatment in symptomatic contact lens wearers: An exploratory study8
Destructive and protective effects and therapeutic targets of IL-36 family cytokines in dry eye disease8
The conjunctival extracellular matrix, related disorders and development of substrates for conjunctival restoration8
Patients with neurotrophic keratitis demonstrate alterations in ocular surface expression of transient receptor potential (TRP) channels7
Blinded by smoke: Wildfire smoke exposure and eye irritation in australian wildland firefighters7
Self-complementary AAV vector therapy for treating corneal cloudiness of mucopolysaccharidosis type VII (MPS VII)7
A novel severity scoring system for murine ocular graft versus host disease and its correlation with CD3+ T cells in the cornea7
Readership awareness series - Paper 5: The peer review process7
Imbalanced IL-37/TNF-α/CTSS signaling disrupts corneal epithelial barrier in a dry eye model in vitro7
The impact of contact lenses on meibomian gland morphology7
The miR-183/96/182 cluster is a checkpoint for resident immune cells and shapes the cellular landscape of the cornea7
Herpes simplex virus-1 conjunctival dendrite in an immunosuppressed patient7
The antipsychotropic drug Duloxetine rescues PAX6 haploinsufficiency of mutant limbal stem cells through inhibition of the MEK/ERK signaling pathway7
Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction: A vehicle-controlled, randomized clinical trial7
Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction over six months of treatment: A Phase 2, vehicle-controlled, randomized extension tria7
Identification of a translatable animal model for dry eye disease using comparative analysis of tear proteins across species7
Comparable meibomian gland changes in patients with and without ocular graft-versus-host disease after hematopoietic stem cell transplantation6
Unique cytokine signature in ocular Stevens-Johnson syndrome non-responders6
Fluorescein CorneoGraphy (FCG): Use of a repurposed fluorescein imaging technique to objectively standardize corneal staining6
Readership awareness series – Paper 9: Retraction of a publication6
Delayed diagnosis of ocular graft-versus-host disease after allogeneic hematopoietic stem cell transplantation6
Detection of SARS-CoV-2 binding receptors and miscellaneous targets as well as mucosal surface area of the human lacrimal drainage system6
Impact of glaucoma medications on the ocular surface and how ocular surface disease can influence glaucoma treatment6
A large hypothesis-free proteomics study investigating serum inflammatory markers as biomarkers of dry eye disease6
A masked study to differentiate in vivo confocal microscopic features of Pythium insidiosum and fungal filaments6
TFOS Lifestyle: Impact of the digital environment on the ocular surface6
Human tear fluid modulates the Pseudomonas aeruginosa transcriptome to alter antibiotic susceptibility6
Management of scleral melt6
Metabolic signatures of tear extracellular vesicles caused by herpes simplex keratitis6
Effects of meibomian gland dysfunction and aqueous deficiency on friction-related disease6
Small fiber neuropathy in the cornea of Covid-19 patients associated with the generation of ocular surface disease6
A multicenter report of the use of plasma rich in growth factors (PRGF) for the treatment of patients with ocular surface diseases in North America6
A tribute to Gary N. Foulks, M.D. (1944–2025) and his contributions to the ocular surface6
Epidemiological insights into Childhood vernal keratoconjunctivitis in India: Unravelling clinical presentation and environmental influences – The EPIC VKC study – Fourth report of the ICMR EYE SEE st6
TFOS Lifestyle Report Introduction: A Lifestyle Epidemic - Ocular Surface Disease6
Clinical trials submissions to The Ocular Surface6
Editorial Board5
The use of in vivo confocal microscopy in fungal keratitis – Progress and challenges5
Short chain fatty acids inhibit corneal inflammatory responses to TLR ligands via the ocular G-protein coupled receptor 435
Peripheral hypertrophic subepithelial corneal degeneration versus Salzmann's nodular degeneration: A clinical and surgical comparison5
The Yin and Yang of non-immune and immune responses in meibomian gland dysfunction5
Omega-3 polyunsaturated fatty acids and corneal nerve health: Current evidence and future directions5
Prevalence and antimicrobial susceptibility pattern of coagulase-negative Staphylococci isolated from ocular infections: A systematic review and meta-analysis5
Preclinical confirmation of UVC efficacy in treating infectious keratitis5
A single institute validation study comparing the international chronic ocular graft-versus-host disease consensus group diagnostic criteria with clinical parameters5
Culture- and non-culture-based approaches reveal unique features of the ocular microbiome in dry eye patients5
Neurotrophic Keratitis: A rare disease that requires proactive screening and orphan drug treatments5
Novel discovery of a lymphatic bridge connecting Schlemm's canal to limbal and conjunctival lymphatic pathway5
A review of the epithelial and stromal effects of corneal collagen crosslinking5
Topical Pharmacologic Treatments for Dry Eye Disease: A Systematic Review5
Readership awareness series – Paper 4: Chatbots and ChatGPT - Ethical considerations in scientific publications5
Matrix glycosaminoglycans and proteoglycans in human cornea organoids and similarities with fetal corneal stages5
Detecting dry eye from ocular surface videos based on deep learning5
Topical 1% 5-fluorouracil eye drops as primary treatment for ocular surface squamous neoplasia: Long-term follow-up study5
Transitory alkali exposure on meibomian gland orifices induces meibomian gland dysfunction5
Meibomian gland stem/progenitor cells: The hunt for gland renewal5
Dry eye disease in the young: A narrative review5
A new option for treatment of severe cicatricial entropion in patients with Stevens-Johnson syndrome5
The power of the adverb5
Concurrent ocular pain in patients with neurotrophic keratopathy4
The prevalence and recurrence risk of bare sclera pterygium surgery in the United States4
Deciphering S1P downregulation and sphingolipid homeostasis disruption in fungal keratitis via multi-omics and MALDI-MSI analysis4
Modified Boston Type-II Keratoprosthesis Implantation with Autologous Auricular Cartilage Reinforcement4
Was Marilyn Monroe myopic and an early adopter of colored contact lenses? A review of the evidence and the early history of colored contact lenses4
Antibiotic treatment for dry eye disease related to meibomian gland dysfunction and blepharitis – A review4
Meibomian gland tortuosity, truncation, and dilation in paediatric dry eye disease: A multi-centre, investigator-masked, cross-sectional study4
Inhibition of ceramide de novo synthesis ameliorates meibomian gland dysfunction induced by SCD1 deficiency4
Gene expression signatures in conjunctival fornix aspirates of patients with dry eye disease associated with Meibomian gland dysfunction. A proof-of-concept study4
Combined therapy of ocular surface disease with plasma rich in growth factors and scleral contact lenses4
The Link module of human TSG-6 (Link_TSG6) promotes wound healing, suppresses inflammation and improves glandular function in mouse models of Dry Eye Disease4
Impaired GSH biosynthesis disrupts eye development, lens morphogenesis and PAX6 function4
Editorial Board4
Pathophysiology of aniridia-associated keratopathy: Developmental aspects and unanswered questions4
Big-bubble DALK: A technique in evolution4
Seeing the unseen: Use of a modified OSDI questionnaire to accurately detect chronic ocular GVHD in a hematology clinic4
New insights into lacrimal gland anatomy using 7T MRI and electron microscopy: Relevance for lacrimal gland targeted therapies and bioengineering4
Cicatricial entropion in eyes with lid margin mucous membrane grafting4
Trends in using mesenchymal stromal/stem cells (MSCs) in treating corneal diseases4
Glycosaminoglycans: Roles in wound healing, formation of corneal constructs and synthetic corneas4
Corneal acetylcholine regulates sensory nerve activity via nicotinic receptors4
Editorial Board4
Human meibomian gland epithelial cell culture models: Current progress, challenges, and future directions4
Managing chronic inflammation in ocular sequelae of Stevens Johnson Syndrome to restore vision4
Tissue-targeted and localized AAV5-DCN and AAV5-PEDF combination gene therapy abrogates corneal fibrosis and concurrent neovascularization in rabbit eyes in vivo4
Calcium-sensing receptor (CaSR) modulates ocular surface chloride transport and its inhibition promotes ocular surface hydration4
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