Ocular Surface

Papers
(The median citation count of Ocular Surface is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Editorial Board127
In vivo calcium imaging of corneal sensory nerves with fluorescent stereoscopic microscopy107
Reassessing interdisciplinary approaches to belantamab mafodotin-induced ocular toxicity: Towards a standardized collaborative model104
Biology and medicine on ocular surface restoration: Advancements and limits of limbal stem cell deficiency treatments74
Long term study of topical interferon α-2b eye drops as primary treatment of ocular surface squamous neoplasia72
Atypical microbial keratitis69
Monkeypox and ocular implications in humans66
Safety of subconjunctival injection of mesenchymal stromal cells in persistent corneal epithelial disease – A phase 1b clinical trial61
Endogenous TSG-6 modulates corneal inflammation following chemical injury56
Corrigendum to “New insights into lacrimal gland anatomy using 7T MRI and electron microscopy: Relevance for lacrimal gland targeted therapies and bioengineering” [Ocul. Surf. 30 (October 2023) 204–2155
Economic burden of keratitis patients with inpatient care: a nationwide, multicenter registry study53
Development and validation of a method to generate phenol red thread tests52
Readership awareness series – Paper 10: Open Access Publishing49
Mechanistic insights into conjunctivalization in limbal stem cell deficiency using a lineage tracing approach48
A pilot randomized controlled trial of topical androgen treatment in dry eye46
Metabolic reprogramming in lacrimal gland GVHD: Stage-specific shifts in acinar cells as drivers of disease progression46
Editorial Board44
The clinical outcomes of minor salivary gland transplantation for severe dry eye disease secondary to chronic Stevens-Johnson syndrome44
Organotypic culture model of mouse meibomian gland as a screening platform for risk factors related to meibomian gland dysfunction43
A prospective self-controlled study on the alterations of the ocular surface and conjunctival transcriptomic profile associated with prolonged exposure to video display terminals43
Modulating the tachykinin: Role of substance P and neurokinin receptor expression in ocular surface disorders42
Predatory bacteria can reduce Pseudomonas aeruginosa induced corneal perforation and proliferation in a rabbit keratitis model39
New disposable esthesiometer (KeraSenseⓇ) to improve diagnosis and management of neurotrophic keratitis38
Diagnostic performance and optimal cut-off values for tear film lipid layer grading and thickness in dry eye disease: An investigator-masked, randomised crossover study36
Tear film changes in symptomatic versus asymptomatic video display terminal users following computer challenge test35
Epidemiology and risk factors for the development of cicatrizing conjunctivitis in chronic ocular graft-versus-host disease35
Chronic inflammation as a proposed risk factor for ocular surface squamous neoplasia34
Effects of age on lacrimal gland bioactive lipids31
Corneal gene therapy: Structural and mechanistic understanding31
Allogeneic mesenchymal stem cell therapy for dry eye disease in patients with Sjögren's syndrome: A randomized clinical trial31
A loss of inter-α-inhibitor Heavy Chain 5 (ITIH5) leads to corneal thinning and increased corneal inflammation following injury and early onset geriatric decline30
Herpes simplex virus, varicella-zoster virus and cytomegalovirus keratitis: Facts for the clinician30
Cytokine levels and clinical characteristics in the tear fluid of patients with atopic dermatitis and atopic keratoconjunctivitis30
5-Fluorouracil in primary, impending recurrent and recurrent pterygium: Systematic review of the efficacy and safety of a surgical adjuvant and intralesional antimetabolite29
TFOS Lifestyle Report: Impact of environmental conditions on the ocular surface29
Investigating the diagnostic utility of non-invasive tear film stability and breakup parameters: A prospective diagnostic accuracy study28
Cyclosporine A 1mg/ml in pediatric blepharokeratoconjunctivitis: Case series of 145 children and young people28
Toxicity and efficacy of type I interferons on the ocular surface: in vitro, animal, and clinical studies28
Interdisciplinary management of belantamab mafodotin-associated ocular toxicity in clinical practice28
Alteration in meibum lipid composition and subjective symptoms due to aging and meibomian gland dysfunction26
TFOS Lifestyle: Impact of nutrition on the ocular surface26
Topical low-dose heparin in ocular Stevens Johnson Syndrome and associated molecular correlations: A randomized controlled pilot study26
Profile of tear lipid mediator as a biomarker of inflammation for meibomian gland dysfunction and ocular surface diseases: Standard operating procedures25
Limiting plastic waste in dry eye practice for environmental sustainability25
Trustworthy research presentations24
Keratoneuropathy23
Host-microbe interactions in cornea22
Effect of cosmetics on the measurement of the tear lipid layer thickness by LipiView®22
Rational design and synthesis of lumican stapled peptides for promoting corneal wound healing21
Expert consensus on pediatric dry eye: Insights from a European Delphi study21
Subconjunctival triamcinolone injection for infectious necrotizing scleritis21
Lacrimal gland regeneration: The unmet challenges and promise for dry eye therapy21
Readership awareness series – Paper 3: Paper mills21
1,5-Dicaffeoylquinic acid from Pseudognaphalium affine ameliorates dry eye disease via suppression of inflammation and protection of the ocular surface20
Investigating conjunctival immune pathways in Sjögren and non-Sjögren disease associated dry eye20
Label-free quantitative imaging of conjunctival goblet cells20
Redefining ocular drug delivery20
Insights into the clinical development of regenerative medical products through a comparison of three cell-based products recently approved for limbal stem cell deficiency20
Ocular pain in ocular graft-versus-host disease patients with neurotrophic keratopathy20
Corneal nerve regeneration is affected by scar location in herpes simplex keratitis: A longitudinal in vivo confocal microscopy study20
Exposure keratopathy in patients undergoing invasive ventilation: Prevalence, severity, and the role of surface lubrication20
A novel artificial intelligence model for diagnosing Acanthamoeba keratitis through confocal microscopy19
Re: Significant errors in the paper by Ballesteros-Sánchez A, Rocha-de-Lossada C and Sánchez-González J. Efficacy of eyelid warming devices as first-step treatment in meibomian gland dysfunction: A sy19
Readership awareness series - Paper 6: How to write a good peer review report?19
Intralesional triamcinolone injection as an adjuvant therapy for refractory cicatrizing conjunctivitis19
Identifying patient-valued outcomes for use in early phase trials of ocular surface disease interventions18
Visual outcomes of children undergoing penetrating keratoplasty in the US18
Conjunctival vessel density analysis as a marker of inflammation in dry eye disease18
Transglutaminase-2 is critical for corneal epithelial barrier function via positive regulation of Claudin-118
Use of a transgenic mouse model for in vivo monitoring of corneal pathologies following Sulfur Mustard Exposure18
Two models of the structures of the lamellae in human meibum and the tear film lipid layer, TFLL18
Changes in conjunctival mononuclear phagocytes and suppressive activity of regulatory macrophages in desiccation induced dry eye18
Deep learning-based classification of fungal and Acanthamoeba keratitis using confocal microscopy17
Corrigendum to “Models for Meibomian gland dysfunction: In vivo and in vitro”, Review article [Ocul. Surf. 32 (2024) 154–165]17
Phenotypic characterization of patients developing chronic dry eye and pain after refractive surgery: A cross-sectional study17
Corneal complications of Sjögren's disease: Insights from a large tertiary ophthalmological care center17
Evaluation of ocular neuropathic pain17
Corneal sensory nerve regulation of tear production through stimulation of transient receptor potential melastatin 8 (TRPM8) channel: A potential new approach for treating dry eye disease17
High-resolution high-contrast in vivo phase imaging of corneal nerves and immune cells in mice17
Optimising the method for visualising mouse meibomian gland using eyelid whole-mount lipid staining17
Fenofibrate ameliorates ocular surface inflammation in diabetic keratopathy17
Readership awareness series – Paper 11: Copyright licensing for scientific publications16
Pipeline: Ocular biostatistics: Proper use of proportions16
Autologous serum tears improve corneal nerve density and sensitivity in patients with ocular graft-versus-host disease-associated dry eye disease16
Smad4 deficiency ameliorates the progressive corneal stroma thinning caused by the loss of Tbr116
Readership awareness series - Paper 1: Ghost authorship16
A randomized, vehicle-controlled, Phase 2b study of two concentrations of the TRPM8 receptor agonist AR-15512 in the treatment of dry eye disease (COMET-1)16
Corrigendum to “TFOS lifestyle: Impact of lifestyle challenges on the ocular surface” [Ocul Surf 28 (2023) 262–303]16
Report on the 2021 Aniridia North America symposium on PAX6, aniridia, and beyond16
Modified technique for sutureless amniotic membrane transplantation in acute Stevens-Johnson syndrome using fibrin sealant16
Benzalkonium chloride, a common ophthalmic preservative, compromises rat corneal cold sensitive nerve activity15
Novel characterization of CXCR4 expressing cells in uninfected and herpes simplex virus-1 infected corneas15
Essential roles of sensory nerve in maintenance of cornea-phenotype in mice15
Exploration of imaging and molecular biomarkers for differentiation of neuropathic corneal pain from dry eye syndrome15
Ocular surface squamous neoplasia: Update on genetics, epigenetics and opportunities for targeted therapy15
Ocular graft-versus-host disease: Experience, incidence, and treatment outcomes at a university-based tertiary care ophthalmology center15
Impact of particulate matter and air pollution on ocular surface disease: A systematic review of preclinical and clinical evidence15
Downregulation of the core circadian gene Nr1d2 in the lacrimal gland contributes to postoperative dry eye disease by impairing lipid metabolism15
The effect of botulinum neurotoxin A injections on meibomian glands and dry eye15
Hyperosmotic stress-induced NLRP3 inflammasome activation via the mechanosensitive PIEZO1 channel in dry eye corneal epithelium14
Response to “Methodological considerations regarding 'Ranking the efficacy of topical treatments for ocular allergy: A network meta-analysis of current evidence'”14
BMAL1 deficiency provokes dry mouth and eyes by down-regulating ITPR2/314
In vivo confocal microscopic study of corneal innervation in Sjögren's Syndrome with or without small fiber neuropathy13
Development and optimization of an ex vivo model of corneal epithelium damage with 1-heptanol: Investigating the influence of donor clinical parameters and MSC-sEV treatment on healing capacity13
Association between systemic medication use and severity of dry eye signs and symptoms in the DRy eye assessment and management (DREAM) study13
IVCM image analysis for limbal stem cell deficiency: quantitative diagnostics of the corneal epithelium post-transplant recovery13
Spontaneous acinar and ductal regrowth after meibomian gland atrophy induced by deletion of FGFR2 in a mouse model13
Pipeline: US FDA efficacy requirements for treatment of ocular surface disease: Drugs vs. medical devices13
Pipeline: Therapeutics – Two views of off-label use13
Tetraspanin CD9-derived peptides inhibit Pseudomonas aeruginosa corneal infection and aid in wound healing of corneal epithelial cells13
Intelligent interferometric analysis of lipid layer thickness for clinical evaluation of dry eye disease13
Letter to the editor regarding “TFOS Lifestyle: Impact of the digital environment on the ocular surface”13
Preservatives and ocular surface disease: A review13
A novel Schirmer strip-based tear matrix metalloproteinase measurement in dry eye evaluation12
Duloxetine enhances PAX6 expression and suppresses innate immune responses in murine LPS-induced corneal inflammation12
Restoration of corneal epithelial barrier function: A possible target for corneal neovascularization12
Cellular senescence promotes meibomian gland dysfunction in a chronic graft-versus-host disease mouse model12
Readership awareness series – Paper 7: An overview of impact factor and other scientometrics12
Letter to Editor: Prospective consecutive case series of patients with neurotrophic keratopathy associated with unilateral total limbal stem cell deficiency caused by severe ocular surface burns12
Pard3 promotes corneal epithelial stratification and homeostasis by regulating apical-basal polarity, cytoskeletal organization and tight junction-mediated barrier function12
Adipose-derived mesenchymal stromal cells: A study on safety and efficacy in ocular inflammation12
Editorial Board12
Delphi panel on neuromodulation as a treatment strategy for dry eye disease: Unlocking the potential of natural tear production12
Epithelial-mesenchymal transition in the lacrimal gland morphogenesis, damage and repair12
Endoplasmic reticulum stress contributes to the development of ocular graft-vs-host disease in the eyelids and the ocular surface11
Editorial Board11
Impact of botulinum toxin type A on ocular pain with neuropathic features11
Umbilical cord-derived mesenchymal stem cell therapy for acute Stevens-Johnson syndrome/Toxic Epidermal Necrolysis with severe ocular involvement11
Mechanoreceptor Piezo1 channel-mediated interleukin expression in conjunctival epithelial cells: Linking mechanical stress to ocular inflammation11
Remission of corneal and peripheral neuropathy after bariatric surgery in people with diabetes11
Topical formulations of Aprepitant are safe and effective in relieving pain and inflammation, and drive neural regeneration11
Multicenter prospective validation study for international chronic ocular graft-versus-host disease consensus diagnostic criteria11
Glycoprotein 340 expression in hyperosmolar stress and infection of corneal epithelial cells11
Editorial Board11
Global burden, risk factors, causative organisms and antibiotic susceptibility patterns in bacterial keratitis11
Effectiveness of adult zoster vaccination in preventing a first episode of zoster keratitis: A large-scale database study11
Density and distribution of dendritiform cells in the peripheral cornea of healthy subjects using in vivo confocal microscopy10
Anti-inflammatory and wound healing potential of medicinal maggot excretions/secretions at the ocular surface10
Decoding the corneal immune microenvironment in healthy and diabetic mice during corneal wound healing10
The multifaceted aspects of ocular allergies: Phenotypes and endotypes10
Alleviative effect of probiotics and prebiotics on dry eye in type 2 diabetic mice through the gut-eye axis10
Ocular involvement in Mycoplasma induced rash and mucositis: A systematic review of the literature10
Lacrimal gland spheroids in tissue specific hydrogel for dry eye modelling10
Readership awareness series – paper 14: The submission Dilemma - How to choose a journal?10
Outcomes of keratolimbal allograft from ABO compatible donors for severe bilateral limbal stem cell deficiency10
The genus decision: Potential impact on ophthalmic pharmaceuticals10
A prospective, longitudinal study to assess progression of ocular surface signs, tear cytokines and protein profiles in young adults10
TFOS Lifestyle Report Executive Summary: A Lifestyle Epidemic - Ocular Surface Disease10
Topical glaucoma medications – Clinical implications for the ocular surface10
Cytarabine chemotherapy induces meibomian gland dysfunction10
Pediatric vs adult Stevens Johnson syndrome/toxic epidermal necrolysis: Ocular outcomes and the role of amniotic membrane10
Tear lymphotoxin-alpha deficiency is associated with conjunctival epitheliopathy in patients with dry eye disease10
Conditional deletion of CD25 in the corneal epithelium reveals sex differences in barrier disruption9
Clinical and genetic profiling of fibromyalgia-associated dry eye: A multifactorial approach9
The conjunctival extracellular matrix, related disorders and development of substrates for conjunctival restoration9
Salivary gland transplantation for dry eye disease: Indications, techniques, and outcomes9
Letter to the Editor regarding “Corneal sensory nerve regulation of tear production through stimulation of transient receptor potential melastatin 8 (TRPM8) channel: A potential new approach for treat9
Readership awareness series – Paper 8: Research ethics and ‘editorial expressions of concern’9
The effect of a biweekly novel selenium sulfide-containing topical treatment in symptomatic contact lens wearers: An exploratory study9
Editorial Board9
Relationships between ocular surface sphingomyelinases, Meibum and Tear Sphingolipids, and clinical parameters of meibomian gland dysfunction8
Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction: A vehicle-controlled, randomized clinical trial8
Differences in pre-surgical baseline tear proteome are associated with persistent post-refractive surgery pain8
Unique cytokine signature in ocular Stevens-Johnson syndrome non-responders8
Blinded by smoke: Wildfire smoke exposure and eye irritation in australian wildland firefighters8
Patients with neurotrophic keratitis demonstrate alterations in ocular surface expression of transient receptor potential (TRP) channels8
Ectoine protects corneal epithelial survival and barrier from hyperosmotic stress by promoting anti-inflammatory cytokine IL-378
Destructive and protective effects and therapeutic targets of IL-36 family cytokines in dry eye disease8
Imbalanced IL-37/TNF-α/CTSS signaling disrupts corneal epithelial barrier in a dry eye model in vitro8
Dry eye disease sustainability8
Self-complementary AAV vector therapy for treating corneal cloudiness of mucopolysaccharidosis type VII (MPS VII)8
Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction over six months of treatment: A Phase 2, vehicle-controlled, randomized extension tria8
Editorial Board8
Electroencephalogram-detected stress levels in the frontal lobe region of patients with dry eye8
Prolonged stability of 1% 5-FU eye drops as topical chemotherapy for ocular surface squamous neoplasia8
Lacrimal gland duct obstruction and dacryops: Unravelling its pathogenesis with proteomics and cellular profiling8
Herpes simplex virus-1 conjunctival dendrite in an immunosuppressed patient8
Fluorescein CorneoGraphy (FCG): Use of a repurposed fluorescein imaging technique to objectively standardize corneal staining8
Identification of a translatable animal model for dry eye disease using comparative analysis of tear proteins across species8
Readership awareness series - Paper 5: The peer review process8
The corneal fibroblast: The Dr. Jekyll underappreciated overseer of the responses to stromal injury8
Diagnostic capacity for fungal keratitis in Africa – Survey in 50 African countries8
MicroRNAs in corneal Diseases: Emerging roles as biomarkers, regulators, and therapeutics7
Impact of glaucoma medications on the ocular surface and how ocular surface disease can influence glaucoma treatment7
Prospective consecutive case series of patients with neurotrophic keratopathy associated with unilateral total limbal stem cell deficiency caused by severe ocular surface burns7
TFOS Lifestyle: Impact of the digital environment on the ocular surface7
Readership awareness series – Paper 9: Retraction of a publication7
The miR-183/96/182 cluster is a checkpoint for resident immune cells and shapes the cellular landscape of the cornea7
A large hypothesis-free proteomics study investigating serum inflammatory markers as biomarkers of dry eye disease7
Comparable meibomian gland changes in patients with and without ocular graft-versus-host disease after hematopoietic stem cell transplantation7
Comprehensive profiling of the human tear fluid miRNome using small RNA sequencing7
A tribute to Gary N. Foulks, M.D. (1944–2025) and his contributions to the ocular surface7
Antibiotic resistance of Pseudomonas aeruginosa from ocular samples in Canada: a 25-year analysis7
A multicenter report of the use of plasma rich in growth factors (PRGF) for the treatment of patients with ocular surface diseases in North America7
A novel severity scoring system for murine ocular graft versus host disease and its correlation with CD3+ T cells in the cornea7
Effects of meibomian gland dysfunction and aqueous deficiency on friction-related disease7
A masked study to differentiate in vivo confocal microscopic features of Pythium insidiosum and fungal filaments7
Detection of SARS-CoV-2 binding receptors and miscellaneous targets as well as mucosal surface area of the human lacrimal drainage system7
Topical pharmacologic treatments for dry eye disease: A systematic review6
Prevalence and antimicrobial susceptibility pattern of coagulase-negative Staphylococci isolated from ocular infections: A systematic review and meta-analysis6
Near complete corneal regeneration after lamellar keratoplasty in rabbits enabled by an in situ photo-crosslinkable dendrimer-hyaluronic acid hydrogel6
Pipeline: The next generation of therapy for ocular surface disease6
Epidemiological insights into Childhood vernal keratoconjunctivitis in India: Unravelling clinical presentation and environmental influences – The EPIC VKC study – Fourth report of the ICMR EYE SEE st6
Readership awareness series – Paper 4: Chatbots and ChatGPT - Ethical considerations in scientific publications6
Delayed diagnosis of ocular graft-versus-host disease after allogeneic hematopoietic stem cell transplantation6
Dry eye disease in the young: A narrative review6
Moxifloxacin-resistant and moxifloxacin-susceptible Staphylococcus aureus Keratitis: Outcomes from a 10-year retrospective study6
Meibomian gland stem/progenitor cells: The hunt for gland renewal6
Recurrent retroprosthetic membranes in Boston Keratoprosthesis Type I: Incidence, risk factors, and complications6
Pipeline: Patient, physician and developer view of drugs vs. devices6
Management of scleral melt6
The cumulative impact of air pollution on dry eye disease: Evidence from the Korea national health and nutrition examination survey (2017-2020)6
Clinical trials submissions to The Ocular Surface6
Preclinical confirmation of UVC efficacy in treating infectious keratitis6
A review of the epithelial and stromal effects of corneal collagen crosslinking6
Metabolic signatures of tear extracellular vesicles caused by herpes simplex keratitis6
Omega-3 polyunsaturated fatty acids and corneal nerve health: Current evidence and future directions6
TFOS Lifestyle Report Introduction: A Lifestyle Epidemic - Ocular Surface Disease6
Progranulin restores diabetic corneal healing by modulating NF-κB–Driven inflammation and neuro-regenerative pathways6
The Yin and Yang of non-immune and immune responses in meibomian gland dysfunction5
Editorial Board5
Matrix glycosaminoglycans and proteoglycans in human cornea organoids and similarities with fetal corneal stages5
Topical 1% 5-fluorouracil eye drops as primary treatment for ocular surface squamous neoplasia: Long-term follow-up study5
Pipeline: Pharmacotherapy of dry eye disease in vertebrates5
Tissue-targeted and localized AAV5-DCN and AAV5-PEDF combination gene therapy abrogates corneal fibrosis and concurrent neovascularization in rabbit eyes in vivo5
The power of the adverb5
Neurotrophic Keratitis: A rare disease that requires proactive screening and orphan drug treatments5
Culture- and non-culture-based approaches reveal unique features of the ocular microbiome in dry eye patients5
Heightened visual light sensitivity discomfort measured by the ocular photosensitivity analyzer is associated with chronic ocular pain5
Calcium-sensing receptor (CaSR) modulates ocular surface chloride transport and its inhibition promotes ocular surface hydration5
Gene expression signatures in conjunctival fornix aspirates of patients with dry eye disease associated with Meibomian gland dysfunction. A proof-of-concept study5
Detecting dry eye from ocular surface videos based on deep learning5
Ultrasonography assessments of meibomian gland as a noninvasive method of detecting changes in morphology5
Transitory alkali exposure on meibomian gland orifices induces meibomian gland dysfunction5
Novel discovery of a lymphatic bridge connecting Schlemm's canal to limbal and conjunctival lymphatic pathway5
Cicatricial entropion in eyes with lid margin mucous membrane grafting5
The ocular surface tear film as a biomarker for systemic health5
Short chain fatty acids inhibit corneal inflammatory responses to TLR ligands via the ocular G-protein coupled receptor 435
Meibomian gland tortuosity, truncation, and dilation in paediatric dry eye disease: A multi-centre, investigator-masked, cross-sectional study4
Editorial Board4
Acanthamoeba keratitis treatment outcomes compared for drug delivery by protocol versus physician's individualised treatment4
Association of tobacco smoking with aqueous deficient and evaporative dry eye disease subtypes: a prospective registry-based case-control study4
Pipeline: Pricing for drugs treating dry eye disease4
Glycosaminoglycans: Roles in wound healing, formation of corneal constructs and synthetic corneas4
Corneal acetylcholine regulates sensory nerve activity via nicotinic receptors4
The roles of neural adaptation and sensitization in contact lens discomfort4
Deciphering S1P downregulation and sphingolipid homeostasis disruption in fungal keratitis via multi-omics and MALDI-MSI analysis4
Tear fluid derived extracellular vesicles for new biomarker discovery4
Past, present, and prospects in microsporidial keratoconjunctivitis- A review4
Was Marilyn Monroe myopic and an early adopter of colored contact lenses? A review of the evidence and the early history of colored contact lenses4
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