Cancer Biology & Therapy

Papers
(The TQCC of Cancer Biology & Therapy is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Correction93
Phase I double-blind, placebo-controlled trial of dolcanatide (SP-333) 27 mg to explore colorectal bioactivity in healthy volunteers60
DDX24 regulates the chemosensitivity of hepatocellular carcinoma to sorafenib via mediating the expression of SNORA1851
Loss of ubiquitin-specific peptidase 18 destabilizes 14-3-3ζ protein and represses lung cancer metastasis42
CPT1A mediates the succinylation of SP5 which activates transcription of PDPK1 to promote the viability and glycolysis of prostate cancer cells41
Correction39
Molecular profiles of different PD-L1 expression in patients with esophageal squamous cell carcinoma39
Tripartite motif-containing protein 50 suppresses triple-negative breast cancer progression by regulating the epithelial–mesenchymal transition34
Evaluating massage therapy for radiation-induced fibrosis in rats: preliminary findings and palpation results32
miRNA-660-3p inhibits malignancy in glioblastoma via negative regulation of APOC1-TGFβ2 signaling pathway31
Immunotherapy resistance in solid tumors: mechanisms and potential solutions30
Clinical application of molecular residual disease detection by circulation tumor DNA in solid cancers and a comparison of technologies: review article30
Clinical and biological determinants of circulating tumor DNA detection and prognostication using a next-generation sequencing panel assay30
Partial treatment response to capmatinib in MET-amplified metastatic intrahepatic cholangiocarcinoma: case report & review of literature28
Targeting gastrointestinal cancers with chimeric antigen receptor (CAR)-T cell therapy27
Silencing ZIC5 suppresses glycolysis and promotes disulfidptosis in lung adenocarcinoma cells25
Linoleic acid exhibits anti-proliferative and anti-invasive activities in endometrial cancer cells and a transgenic model of endometrial cancer24
GdX inhibits the occurrence and progression of breast cancer by negatively modulating the activity of STAT324
MiR-128-1-5p inhibits cell proliferation and induces cell apoptosis via targeting PRKCQ in colorectal cancer24
SATB1 mediated tumor colonization and β-catenin nuclear localization are associated with colorectal cancer progression23
Requirement for containing etoposide in the initial treatment of lymphoma associated hemophagocytic lymphohistiocytosis23
Small extracellular vesicle-mediated ITGB6 siRNA delivery downregulates the αVβ6 integrin and inhibits adhesion and migration of recipient prostate cancer cells23
Bibliometric analysis of autophagy in the diagnosis and treatment of osteosarcoma: a bibliometric analysis (2007–2023)22
LINC01060 knockdown inhibits osteosarcoma cell malignant behaviors in vitro and tumor growth and metastasis in vivo through the PI3K/Akt s22
Nucleo-cytoplasmic shuttling of 14-3-3 epsilon carrying hnRNP C promotes autophagy21
Isolated pulmonary metastases in pancreatic ductal adenocarcinoma: a review of current evidence21
Antibody dependent cell-mediated cytotoxicity selection pressure induces diverse mechanisms of resistance20
Mutant PIK3CA as a negative predictive biomarker for treatment with a highly selective PIM1 inhibitor in human colon cancer20
Aldolase A promotes cervical cancer cell radioresistance by regulating the glycolysis and DNA damage after irradiation19
CRC-derived exosomes containing the RNA binding protein HuR promote lung cell proliferation by stabilizing c-Myc mRNA19
Clock in radiation oncology clinics: cost-free modality to alleviate treatment-related toxicity19
NDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma19
PCBP1 regulates LIFR through FAM3C to maintain breast cancer stem cell self-renewal and invasiveness18
CDH2 and CDH13 as potential prognostic and therapeutic targets for adrenocortical carcinoma18
Autophagic degradation of CDK4 is responsible for G0/G1 cell cycle arrest in NVP-BEZ235-treated neuroblastoma18
The impact of drug-eluting bead (vs. conventional) transarterial chemoembolization on hepatic fibrosis in treating intermediate or advanced hepatocellular carcinoma17
Liu-Shen-Wan inhibits PI3K/Akt and TRPV1 signaling alleviating bone cancer pain in rats17
A positive feedback loop of SRSF9/USP22/ZEB1 promotes the progression of ovarian cancer17
NRSN2 promotes the malignant behavior of HPV-transfected laryngeal carcinoma cells through AMPK/ULK1 pathway mediated autophagy activation17
Long-term effects of neoadjuvant chemotherapy in variant histology locally advanced colon cancer: a propensity score-matched analysis17
Navigating precision: the crucial role of next-generation sequencing recurrence risk assessment in tailoring adjuvant therapy for hormone receptor-positive, human epidermal growth factor Receptor2-neg17
Plasma KRAS mutations predict the early recurrence after surgical resection of pancreatic cancer16
Correction16
Robust prediction of glioma prognosis by hypoxia-induced ferroptosis genes: VEGFA-XBP1 co-expression for salvage therapy16
HSF1 is involved in immunotherapeutic response through regulating APOJ/STAT3-mediated PD-L1 expression in hepatocellular carcinoma16
The critical role of tumor microbiome in cancer immunotherapy16
SOX2 inhibits LLGL2 polarity protein in esophageal squamous cell carcinoma via miRNA-142-3p16
DLAT promotes triple-negative breast cancer progression via YAP1 activation15
High tumor amplification burden is associated with TP53 mutations in the pan-cancer setting15
Acquired resistance to crizotinib in novel CDK14-ALK and CLTC-ALK fusions of ALK-positive large B-cell lymphoma identified by next-generation sequencing15
Lenvatinib promotes hepatocellular carcinoma pyroptosis by regulating GSDME palmitoylation15
CDK2 inhibition disorders centrosome stoichiometry and alters cellular outcomes in aneuploid cancer cells15
The anticancer mechanisms of Toxoplasma gondii rhoptry protein 16 on lung adenocarcinoma cells15
Novel specific activity-based probes validate KLK proteases as druggable targets15
Prognostic value of pretreatment procalcitonin and neutrophil–lymphocyte ratio in extensive-stage small-cell lung cancer14
Cyclin-dependent kinase 7/9 inhibitor SNS-032 induces apoptosis in diffuse large B-cell lymphoma cells14
CD8α Structural Domains Enhance GUCY2C CAR-T Cell Efficacy14
Flotillin-1 enhances radioresistance through reducing radiation-induced DNA damage and promoting immune escape via STING signaling pathway in non-small cell lung cancer14
Single whole genome sequencing analysis blazes the trail for precision medicine14
MiR-378a-5p exerts a radiosensitizing effect on CRC through LRP8/β-catenin axis14
Targeting mitochondrial tyrosyl-tRNA synthetase YARS2 suppresses colorectal cancer progression14
Highly enriched exosomal lncRNA OIP5-AS1 regulates gastrointestinal stromal tumor (GIST) resistance to sunitinib through miR-145 and SOX914
Effect of extracellular vesicle ZNF280B derived from lung cancer stem cells on lung cancer progression13
WYC-209 inhibited GC malignant progression by down-regulating WNT4 through RARα13
Agent-based modeling in cancer biomedicine: applications and tools for calibration and validation13
Correction13
CX43 down-regulation promotes cell aggressiveness and 5-fluorouracil-resistance by attenuating cell stiffness in colorectal carcinoma13
Correction13
CircSETD2 inhibits YAP1 by interaction with HuR during breast cancer progression13
The human microbiome and cancer: a diagnostic and therapeutic perspective13
β-amino acid substitution in the SIINFEKL antigen alters immunological recognition13
Fusobacterium nucleatum in tumors: from tumorigenesis to tumor metastasis and tumor resistance13
Cancer-associated fibroblasts derived extracellular vesicles promote angiogenesis of colorectal adenocarcinoma cells through miR-135b-5p/FOXO1 axis13
Angiotensin receptor blockade and stereotactic body radiation therapy for early stage lung cancer ARB & SBRT for early stage lung cancer12
MiR-18a-5p attenuates HER2-positive breast cancer development by regulating PI3K/AKT pathway12
Feasibility and safety of targeting mitochondria for cancer therapy – preclinical characterization of gamitrinib, a first-in-class, mitochondriaL-targeted small molecule Hsp90 inhibitor12
Salidroside inhibited the proliferation of gastric cancer cells through up-regulating tumor suppressor miR-1343-3p and down-regulating MAP3K6/MMP24 signal molecules12
Real-time luminescence enables continuous drug–response analysis in adherent and suspension cell lines12
Repression of the SUMO-conjugating enzyme UBC9 is associated with lowered double minutes and reduced tumor progression12
Establishment of a visualized mouse orthotopic xenograft model of nasopharyngeal carcinoma12
Repeated treatments of Capan-1 cells with PARP1 and Chk1 inhibitors promote drug resistance, migration and invasion11
CircATP5C1 promotes triple-negative breast cancer progression by binding IGF2BP2 to modulate CSF-1 secretion11
Correction11
Association between the IL1B-511 C>T polymorphism and the risk of hematologic malignancies: data from a meta-analysis11
Dead or alive? Pitfall of survival analysis with TCGA datasets11
MGAT4EP promotes tumor progression and serves as a prognostic marker for breast cancer11
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