Cancer Biology & Therapy

Article	Citations
A comparison of cell death pathways in three different kinds of human lung cancer cell lines following hematoporphyrin derivative-mediated photodynamic therapy	101
Advancements in exosome-based cancer diagnosis: from chipsets to nano vaccine	61
Evaluating massage therapy for radiation-induced fibrosis in rats: preliminary findings and palpation results	61
Clinical application of molecular residual disease detection by circulation tumor DNA in solid cancers and a comparison of technologies: review article	52
Immunotherapy resistance in solid tumors: mechanisms and potential solutions	48
DDX24 regulates the chemosensitivity of hepatocellular carcinoma to sorafenib via mediating the expression of SNORA18	46
miRNA-660-3p inhibits malignancy in glioblastoma via negative regulation of APOC1-TGFβ2 signaling pathway	45
Molecular profiles of different PD-L1 expression in patients with esophageal squamous cell carcinoma	42
Correction	41
Dual role of CXCL10 in cancer progression: implications for immunotherapy and targeted treatment‎	35
Tripartite motif-containing protein 50 suppresses triple-negative breast cancer progression by regulating the epithelial–mesenchymal transition	35
Loss of ubiquitin-specific peptidase 18 destabilizes 14-3-3ζ protein and represses lung cancer metastasis	34
MiR-128-1-5p inhibits cell proliferation and induces cell apoptosis via targeting PRKCQ in colorectal cancer	33
CPT1A mediates the succinylation of SP5 which activates transcription of PDPK1 to promote the viability and glycolysis of prostate cancer cells	33
GdX inhibits the occurrence and progression of breast cancer by negatively modulating the activity of STAT3	31
Silencing ZIC5 suppresses glycolysis and promotes disulfidptosis in lung adenocarcinoma cells	30
Partial treatment response to capmatinib in MET-amplified metastatic intrahepatic cholangiocarcinoma: case report & review of literature	29
Small extracellular vesicle-mediated ITGB6 siRNA delivery downregulates the αVβ6 integrin and inhibits adhesion and migration of recipient prostate cancer cells	28
Linoleic acid exhibits anti-proliferative and anti-invasive activities in endometrial cancer cells and a transgenic model of endometrial cancer	27
SATB1 mediated tumor colonization and β-catenin nuclear localization are associated with colorectal cancer progression	27
Targeting gastrointestinal cancers with chimeric antigen receptor (CAR)-T cell therapy	27
Nucleo-cytoplasmic shuttling of 14-3-3 epsilon carrying hnRNP C promotes autophagy	25
Antibody dependent cell-mediated cytotoxicity selection pressure induces diverse mechanisms of resistance	25
USP7 overexpression prevents the progression of clear cell renal cell carcinoma by enhancing pyroptosis via TRIP12 deubiquitination	24
Isolated pulmonary metastases in pancreatic ductal adenocarcinoma: a review of current evidence	23

Aldolase A promotes cervical cancer cell radioresistance by regulating the glycolysis and DNA damage after irradiation	23
Bibliometric analysis of autophagy in the diagnosis and treatment of osteosarcoma: a bibliometric analysis (2007–2023)	23
Mutant PIK3CA as a negative predictive biomarker for treatment with a highly selective PIM1 inhibitor in human colon cancer	23
Requirement for containing etoposide in the initial treatment of lymphoma associated hemophagocytic lymphohistiocytosis	22
LINC01060 knockdown inhibits osteosarcoma cell malignant behaviors in vitro and tumor growth and metastasis in vivo through the PI3K/Akt s	22
A positive feedback loop of SRSF9/USP22/ZEB1 promotes the progression of ovarian cancer	21
NRSN2 promotes the malignant behavior of HPV-transfected laryngeal carcinoma cells through AMPK/ULK1 pathway mediated autophagy activation	20
Liu-Shen-Wan inhibits PI3K/Akt and TRPV1 signaling alleviating bone cancer pain in rats	20
NDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma	20
Autophagic degradation of CDK4 is responsible for G0/G1 cell cycle arrest in NVP-BEZ235-treated neuroblastoma	19
CDH2 and CDH13 as potential prognostic and therapeutic targets for adrenocortical carcinoma	19
Navigating precision: the crucial role of next-generation sequencing recurrence risk assessment in tailoring adjuvant therapy for hormone receptor-positive, human epidermal growth factor Receptor2-neg	19
CRC-derived exosomes containing the RNA binding protein HuR promote lung cell proliferation by stabilizing c-Myc mRNA	19
PCBP1 regulates LIFR through FAM3C to maintain breast cancer stem cell self-renewal and invasiveness	18
Correction	18
SOX2 inhibits LLGL2 polarity protein in esophageal squamous cell carcinoma via miRNA-142-3p	18
Long-term effects of neoadjuvant chemotherapy in variant histology locally advanced colon cancer: a propensity score-matched analysis	18
The impact of drug-eluting bead (vs. conventional) transarterial chemoembolization on hepatic fibrosis in treating intermediate or advanced hepatocellular carcinoma	18
The critical role of tumor microbiome in cancer immunotherapy	18
Clock in radiation oncology clinics: cost-free modality to alleviate treatment-related toxicity	18
Loss of ACSL1 fuels ferroptosis resistance in clear cell renal carcinoma	18
Robust prediction of glioma prognosis by hypoxia-induced ferroptosis genes: VEGFA-XBP1 co-expression for salvage therapy	18
DLAT promotes triple-negative breast cancer progression via YAP1 activation	17
Acquired resistance to crizotinib in novel CDK14-ALK and CLTC-ALK fusions of ALK-positive large B-cell lymphoma identified by next-generation sequencing	17
Lenvatinib promotes hepatocellular carcinoma pyroptosis by regulating GSDME palmitoylation	17
CD8α Structural Domains Enhance GUCY2C CAR-T Cell Efficacy	17
The anticancer mechanisms of Toxoplasma gondii rhoptry protein 16 on lung adenocarcinoma cells	17
MiR-378a-5p exerts a radiosensitizing effect on CRC through LRP8/β-catenin axis	17
Prognostic value of pretreatment procalcitonin and neutrophil–lymphocyte ratio in extensive-stage small-cell lung cancer	17
Highly enriched exosomal lncRNA OIP5-AS1 regulates gastrointestinal stromal tumor (GIST) resistance to sunitinib through miR-145 and SOX9	17
HSF1 is involved in immunotherapeutic response through regulating APOJ/STAT3-mediated PD-L1 expression in hepatocellular carcinoma	17
Novel specific activity-based probes validate KLK proteases as druggable targets	17
Flotillin-1 enhances radioresistance through reducing radiation-induced DNA damage and promoting immune escape via STING signaling pathway in non-small cell lung cancer	16
Single whole genome sequencing analysis blazes the trail for precision medicine	16
WYC-209 inhibited GC malignant progression by down-regulating WNT4 through RARα	16
High tumor amplification burden is associated with TP53 mutations in the pan-cancer setting	16
Correction	16
β-amino acid substitution in the SIINFEKL antigen alters immunological recognition	16
CDK2 inhibition disorders centrosome stoichiometry and alters cellular outcomes in aneuploid cancer cells	16
Effect of extracellular vesicle ZNF280B derived from lung cancer stem cells on lung cancer progression	16
The human microbiome and cancer: a diagnostic and therapeutic perspective	15
Cyclin-dependent kinase 7/9 inhibitor SNS-032 induces apoptosis in diffuse large B-cell lymphoma cells	14
CircSETD2 inhibits YAP1 by interaction with HuR during breast cancer progression	14
Targeting mitochondrial tyrosyl-tRNA synthetase YARS2 suppresses colorectal cancer progression	14
Cancer-associated fibroblasts derived extracellular vesicles promote angiogenesis of colorectal adenocarcinoma cells through miR-135b-5p/FOXO1 axis	14
Agent-based modeling in cancer biomedicine: applications and tools for calibration and validation	14
MGAT4EP promotes tumor progression and serves as a prognostic marker for breast cancer	13
Fusobacterium nucleatum in tumors: from tumorigenesis to tumor metastasis and tumor resistance	13
Salidroside inhibited the proliferation of gastric cancer cells through up-regulating tumor suppressor miR-1343-3p and down-regulating MAP3K6/MMP24 signal molecules	13
CX43 down-regulation promotes cell aggressiveness and 5-fluorouracil-resistance by attenuating cell stiffness in colorectal carcinoma	13

Correction	13
Real-time luminescence enables continuous drug–response analysis in adherent and suspension cell lines	13
Association between the IL1B-511 C>T polymorphism and the risk of hematologic malignancies: data from a meta-analysis	12
CircATP5C1 promotes triple-negative breast cancer progression by binding IGF2BP2 to modulate CSF-1 secretion	12
Repression of the SUMO-conjugating enzyme UBC9 is associated with lowered double minutes and reduced tumor progression	12
Establishment of a visualized mouse orthotopic xenograft model of nasopharyngeal carcinoma	12
Angiotensin receptor blockade and stereotactic body radiation therapy for early stage lung cancer ARB & SBRT for early stage lung cancer	12
Influence of genetic polymorphisms in vascular endothelial-related genes on the clinical outcome of axitinib in patients with metastatic renal cell carcinoma	11
First-line treatments for KRAS-mutant non-small cell lung cancer: current state and future perspectives	11
Roles of TRPM channels in glioma	11
MiR-18a-5p attenuates HER2-positive breast cancer development by regulating PI3K/AKT pathway	11
Repeated treatments of Capan-1 cells with PARP1 and Chk1 inhibitors promote drug resistance, migration and invasion	11
Feasibility and safety of targeting mitochondria for cancer therapy – preclinical characterization of gamitrinib, a first-in-class, mitochondriaL-targeted small molecule Hsp90 inhibitor	11
Amino-truncated NOV expression and its correlation with clinicopathologic features, prognosis, metastasis, and chemoresistance in bladder cancer	10
Clinical significance of WT1 in the evaluation of therapeutic effect and prognosis of non-M3 acute myeloid leukemia	10
Tumor-derived exosomal miR-1247-3p promotes angiogenesis in bladder cancer by targeting FOXO1	10
M6A-mediated molecular patterns and tumor microenvironment infiltration characterization in nasopharyngeal carcinoma	10
CD46 and CD59 inhibitors enhance complement-dependent cytotoxicity of anti-CD38 monoclonal antibodies daratumumab and isatuximab in multiple myeloma and other B-cell malignancy cells	10
Knockdown of NDUFAF6 inhibits breast cancer progression via promoting mitophagy and apoptosis	10
SLX1 silencing overcomes Olaparib resistance in metastatic castration-resistant prostate cancer by disrupting SLX4-mediated DNA repair complexes	10
TP53AIP1 induce autophagy via the AKT/mTOR signaling pathway in the breast cancer cells	10
Integrating DOI in T classification improves the predictive performance of laryngeal cancer staging	10
Chaperonin containing TCP1 subunit 6A may activate Notch and Wnt pathways to facilitate the malignant behaviors and cancer stemness in oral squamous cell carcinoma	10
BRG1 promotes liver cancer cell proliferation and metastasis by enhancing mitochondrial function and ATP5A1 synthesis through TOMM40	9
Exosomal miR-122-5p for regulation of secretory functions of fibroblasts and promotion of breast cancer metastasis by targeting MKP-2: an experimental study	9
S-1-based concurrent chemoradiotherapy plus nimotuzumab in patients with locally advanced esophageal squamous cell carcinoma who failed neoadjuvant therapy: a real-world prospective study	9
Netrin-1 inducing antiapoptotic effect of acute myeloid leukemia cells in a concentration-dependent manner through the Unc-5 netrin receptor B-focal adhesion kinase axis	9
The antipsychotic drug pimozide promotes apoptosis through the RAF/ERK pathway and enhances autophagy in breast cancer cells	9
VAMP8 suppresses the metastasis via DDX5/β-catenin signal pathway in osteosarcoma	9
Effects of combined radiotherapy with immune checkpoint blockade on immunological memory in luminal-like subtype murine bladder cancer model	9
Cyclophilin A: promising target in cancer therapy	9
Targeting CDK9 with selective inhibitors or degraders in tumor therapy: an overview of recent developments	8
Targeting long non-coding RNA PVT1/TGF-β/Smad by p53 prevents glioma progression	8
Combination of metformin/efavirenz/fluoxetine exhibits profound anticancer activity via a cancer cell-specific ROS amplification	8
Drug repurposing based on differentially expressed genes suggests drug combinations with possible synergistic effects in treatment of lung adenocarcinoma	8
Knockdown of LINC00511 enhances radiosensitivity of lung adenocarcinoma via regulating miR-497-5p/SMAD3	8
Neuroendocrine gene subsets are uniquely dysregulated in prostate adenocarcinoma	8
RSK4 promotes the metastasis of clear cell renal cell carcinoma by activating RUNX1-mediated angiogenesis	8
Extracellular vesicle-packaged miR-4253 secreted by cancer-associated fibroblasts facilitates cell proliferation in gastric cancer by inducing macrophage M2 polarization	8
The prognostic marker KRT81 is involved in suppressing CD8 + T cells and predicts immunotherapy response for triple-negative breast cancer	8
IFN-γ downregulates miR-4319 to enhance NLRC5 and MHC-I expression in MHC-I-deficient breast cancer cells	8
USP44 promotes chemotherapeutic drug resistance of triple negative breast cancer through EZH2 protein stability	8
PSMD12 promotes the activation of the MEK-ERK pathway by upregulating KIF15 to promote the malignant progression of liver cancer	8
Obesity reduced survival with 5-fluorouracil and did not protect against chemotherapy-induced cachexia or immune cell cytotoxicity in mice	8
The correlation between serum bone metabolism indexes and bone disease and survival in newly diagnosed multiple myeloma patients	7
P4HA2 promotes tumor progression and is transcriptionally regulated by SP1 in colorectal cancer	7
METTL14 decreases FTH1 mRNA stability via m6A methylation to promote sorafenib-induced ferroptosis of cervical cancer	7
Personalized functional profiling using ex-vivo patient-derived spheroids points out the potential of an antiangiogenic treatment in a patient with a metastatic lung atypical carcinoid	7
Role of glutaminyl-peptide cyclotransferase in breast cancer doxorubicin sensitivity	7
Fractionated radiotherapy initiated at the early stage of bone metastasis is effective to prolong survival in mouse model	7
Analysis of neuroglia and immune cells in the tumor microenvironment of breast cancer brain metastasis	7
Epigenetic drugs induce the potency of classic chemotherapy, suppress post-treatment re-growth of breast cancer, but preserve the wound healing ability of stem cells	7
RND1 inhibits epithelial-mesenchymal transition and temozolomide resistance of glioblastoma via AKT/GSK3-β pathway	7
MiR-135a-3p inhibits the progression of prostate cancer by targeting TLR4	7
The polymeric fluoropyrimidine CF10 overcomes limitations of 5-FU in pancreatic ductal adenocarcinoma cells through increased replication stress	7
BMSC-derived exosomal lncRNA PTENP1 suppresses the malignant phenotypes of bladder cancer by upregulating SCARA5 expression	7
Electrochemical biosensing in oncology: a review advancements and prospects for cancer diagnosis	7
NAALADL2-AS2 functions as a competing endogenous RNA to regulate apoptosis and drug resistance in DLBCL	7
The efficacy of induction chemotherapy or adjuvant chemotherapy added to concurrent chemoradiotherapy in T3-4N0-1M0 nasopharyngeal carcinoma: a propensity score-matched analysis	7
Deep and lasting response and acquired resistance to BRAFV600E targeting in a low-grade ovarian cancer patient	7
Targeting the IKZF1/BCL-2 axis as a novel therapeutic strategy for treating acute T-cell lymphoblastic leukemia	6
PLK4 inhibitor exhibits antitumor effect and synergizes sorafenib via arresting cell cycle and inactivating Wnt/β-catenin pathway in anaplastic thyroid cancer	6
Mutually exclusive teams-like patterns of gene regulation characterize phenotypic heterogeneity along the noradrenergic-mesenchymal axis in neuroblastoma	6
Upregulation of TTYH3 by lncRNA LUCAT1 through interacting with ALYREF facilitates the metastasis in non-small cell lung cancer	6
Lipopolysaccharide (LPS) stimulation of Pancreatic Ductal Adenocarcinoma (PDAC) and macrophages activates the NLRP3 inflammasome that influences the levels of pro-inflammatory cytokines in a co-cultur	6
Caspase 3-specific cleavage of ubiquitin-specific peptidase 48 enhances drug-induced apoptosis in AML	6
N6-methyladenosine-regulated ADIRF impairs lung adenocarcinoma metastasis and serves as a potential prognostic biomarker	6
NAT10 promotes the tumorigenesis and progression of laryngeal squamous cell carcinoma through ac4C modification of FOXM1 mRNA	6
hsa_circ_0020378 regulating miR-339-3p/COL1A1 promotes osteosarcoma progression	6
EGR1/ LINC00839 /SOX5 axis modulates migration, invasion and Gemcitabine resistance of bladder cancer cells	6
Targeted FGFR/VEGFR/PDGFR inhibition with dovitinib enhances the effects of nab-paclitaxel in preclinical gastric cancer models	6
Patient-derived organoids (PDOs) as a promising platform for personalized treatment of colorectal cancer: current applications and future challenges	6
POLE2 silencing inhibits the progression of colorectal carcinoma cells via wnt signaling axis	6
Ras interacting protein 1 facilitated proliferation and invasion of diffuse large B-cell lymphoma cells	6
Carcinoma-associated fibroblasts release microRNA-331-3p containing extracellular vesicles to exacerbate the development of pancreatic cancer via the SCARA5-FAK axis	6
Ruangan Lidan decoction inhibits the growth and metastasis of liver cancer by downregulating miR-9-5p and upregulating PDK4	6
CAFs-derived small extracellular vesicles circN4BP2L2 promotes proliferation and metastasis of colorectal cancer via miR-664b-3p/HMGB3 pathway	6
NVP-2, in combination with Orlistat, represents a promising therapeutic strategy for acute myeloid leukemia	6
Correction	5
The predictors of lymphopenia and its effects on survival in locally advanced esophageal squamous cell carcinoma	5

PINCH-1 promotes tumor growth and metastasis by enhancing DRP1-mediated mitochondrial fission in head and neck squamous cell carcinoma	5
MOICS, a novel classier deciphering immune heterogeneity and aid precise management of clear cell renal cell carcinoma at multiomics level	5
Arntl-induced upregulation of DUSP1 inhibits tumor progression in esophageal squamous cell carcinoma by inactivating ERK signaling	5
BTF3 promotes proliferation and glycolysis in hepatocellular carcinoma by regulating GLUT1	5
Epigenetic silencing ZSCAN23 promotes pancreatic cancer growth by activating Wnt signaling	5
Graphene quantum dots mediated magnetic chitosan drug delivery nanosystems for targeting synergistic photothermal-chemotherapy of hepatocellular carcinoma	5
KLF4 targets RAB26 and decreases 5-FU resistance through inhibiting autophagy in colon cancer	5
Sinapine thiocyanate exhibited anti-colorectal cancer effects by inhibiting KRT6A/S100A2 axis	5
PCK2 promotes invasion and epithelial-to-mesenchymal transition in triple-negative breast cancer by promoting TGF-β/SMAD3 signaling through inhibiting TRIM67-mediated SMAD3 ubiquiti	5
Molecular features, biological behaviors and clinical implications of m 5 C RNA methylation modification regulators in gastrointestinal cancers	5
Exosome-transmitted hsa_circ_0012634 suppresses pancreatic ductal adenocarcinoma progression through regulating miR-147b/HIPK2 axis	5
A study on metabolic characteristics and metabolic markers of gastrointestinal tumors	5
LncRNA DUXAP8 induces breast cancer radioresistance by modulating the PI3K/AKT/mTOR pathway and the EZH2-E-cadherin/RHOB pathway	5
Pan-cancer analysis of ARID family members as novel biomarkers for immune checkpoint inhibitor therapy	5
STEAP2 promotes osteosarcoma progression by inducing epithelial–mesenchymal transition via the PI3K/AKT/mTOR signaling pathway and is regulated by EFEMP2	5