Cancer Biology & Therapy

Article	Citations
Evaluating massage therapy for radiation-induced fibrosis in rats: preliminary findings and palpation results	86
CPT1A mediates the succinylation of SP5 which activates transcription of PDPK1 to promote the viability and glycolysis of prostate cancer cells	76
Clinical application of molecular residual disease detection by circulation tumor DNA in solid cancers and a comparison of technologies: review article	64
Correction	62
Tripartite motif-containing protein 50 suppresses triple-negative breast cancer progression by regulating the epithelial–mesenchymal transition	54
A novel biochip-based liquid biopsy for extracellular vesicle RNA detection in prostate cancer	47
Advances in natural killer cell immunotherapy for hematologic malignancies	43
Immunotherapy resistance in solid tumors: mechanisms and potential solutions	41
Dual role of CXCL10 in cancer progression: implications for immunotherapy and targeted treatment‎	40
A comparison of cell death pathways in three different kinds of human lung cancer cell lines following hematoporphyrin derivative-mediated photodynamic therapy	39
Epigenetic silencing L3MBTL4 sensitizes esophageal cancer to DNA-PKcs inhibitor	37
DDX24 regulates the chemosensitivity of hepatocellular carcinoma to sorafenib via mediating the expression of SNORA18	37
Molecular profiles of different PD-L1 expression in patients with esophageal squamous cell carcinoma	37
Advancements in exosome-based cancer diagnosis: from chipsets to nano vaccine	35
miRNA-660-3p inhibits malignancy in glioblastoma via negative regulation of APOC1-TGFβ2 signaling pathway	33
GdX inhibits the occurrence and progression of breast cancer by negatively modulating the activity of STAT3	32
MiR-128-1-5p inhibits cell proliferation and induces cell apoptosis via targeting PRKCQ in colorectal cancer	28
Protein lactylation: molecular mechanisms underlying lactate-driven tumorigenesis and cancer progression	28
Linoleic acid exhibits anti-proliferative and anti-invasive activities in endometrial cancer cells and a transgenic model of endometrial cancer	27
SATB1 mediated tumor colonization and β-catenin nuclear localization are associated with colorectal cancer progression	27
Silencing ZIC5 suppresses glycolysis and promotes disulfidptosis in lung adenocarcinoma cells	26
The MYBL2-GTSE1 axis promotes laryngeal squamous cell carcinoma progression by regulating PI3K/AKT-dependent glycolytic reprogramming	26
USP7 overexpression prevents the progression of clear cell renal cell carcinoma by enhancing pyroptosis via TRIP12 deubiquitination	26
Nucleo-cytoplasmic shuttling of 14-3-3 epsilon carrying hnRNP C promotes autophagy	24
Mutant PIK3CA as a negative predictive biomarker for treatment with a highly selective PIM1 inhibitor in human colon cancer	24

Evaluating carboplatin and PARP inhibitor combination efficacy using high-grade serous carcinoma spheroids and organoids	24
Aldolase A promotes cervical cancer cell radioresistance by regulating the glycolysis and DNA damage after irradiation	23
LINC01060 knockdown inhibits osteosarcoma cell malignant behaviors in vitro and tumor growth and metastasis in vivo through the PI3K/Akt s	23
Bibliometric analysis of autophagy in the diagnosis and treatment of osteosarcoma: a bibliometric analysis (2007–2023)	23
Antibody dependent cell-mediated cytotoxicity selection pressure induces diverse mechanisms of resistance	23
PCBP1 regulates LIFR through FAM3C to maintain breast cancer stem cell self-renewal and invasiveness	22
Isolated pulmonary metastases in pancreatic ductal adenocarcinoma: a review of current evidence	22
Parthenolide inhibits the progression of intrahepatic cholangiocarcinoma by promoting ferroptosis through inhibiting UBD	22
CDH2 and CDH13 as potential prognostic and therapeutic targets for adrenocortical carcinoma	21
Navigating precision: the crucial role of next-generation sequencing recurrence risk assessment in tailoring adjuvant therapy for hormone receptor-positive, human epidermal growth factor Receptor2-neg	21
A positive feedback loop of SRSF9/USP22/ZEB1 promotes the progression of ovarian cancer	20
The impact of drug-eluting bead (vs. conventional) transarterial chemoembolization on hepatic fibrosis in treating intermediate or advanced hepatocellular carcinoma	20
Autophagic degradation of CDK4 is responsible for G0/G1 cell cycle arrest in NVP-BEZ235-treated neuroblastoma	20
NRSN2 promotes the malignant behavior of HPV-transfected laryngeal carcinoma cells through AMPK/ULK1 pathway mediated autophagy activation	20
Long-term effects of neoadjuvant chemotherapy in variant histology locally advanced colon cancer: a propensity score-matched analysis	20
Lenvatinib potentiates the antitumor efficacy of combined radiotherapy and PD-L1 blockade in lung adenocarcinoma	19
NDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma	19
Liu-Shen-Wan inhibits PI3K/Akt and TRPV1 signaling alleviating bone cancer pain in rats	19
Correction	18
Downregulation of the lncRNA PGM5P4-AS1 predicts poor prognosis and drives breast cancer progression through miR-3664-5p/KLF9	18
The critical role of tumor microbiome in cancer immunotherapy	17
Loss of ACSL1 fuels ferroptosis resistance in clear cell renal carcinoma	17
Potential therapeutic GSK-3β inhibitor 9-ING-41 is active in combination with venetoclax in double-hit lymphoma (DHL)	17
SOX2 inhibits LLGL2 polarity protein in esophageal squamous cell carcinoma via miRNA-142-3p	17
Prognostic value of pretreatment procalcitonin and neutrophil–lymphocyte ratio in extensive-stage small-cell lung cancer	17
Robust prediction of glioma prognosis by hypoxia-induced ferroptosis genes: VEGFA-XBP1 co-expression for salvage therapy	17
DLAT promotes triple-negative breast cancer progression via YAP1 activation	17
Flotillin-1 enhances radioresistance through reducing radiation-induced DNA damage and promoting immune escape via STING signaling pathway in non-small cell lung cancer	17
Nuclear translocation of Cx43 promotes to CRC progression and associates with β-catenin accumulation	16
High tumor amplification burden is associated with TP53 mutations in the pan-cancer setting	16
CDK2 inhibition disorders centrosome stoichiometry and alters cellular outcomes in aneuploid cancer cells	15
Acquired resistance to crizotinib in novel CDK14-ALK and CLTC-ALK fusions of ALK-positive large B-cell lymphoma identified by next-generation sequencing	14
Novel specific activity-based probes validate KLK proteases as druggable targets	14
Lenvatinib promotes hepatocellular carcinoma pyroptosis by regulating GSDME palmitoylation	14
The anticancer mechanisms of Toxoplasma gondii rhoptry protein 16 on lung adenocarcinoma cells	14
MiR-378a-5p exerts a radiosensitizing effect on CRC through LRP8/β-catenin axis	14
Highly enriched exosomal lncRNA OIP5-AS1 regulates gastrointestinal stromal tumor (GIST) resistance to sunitinib through miR-145 and SOX9	13
Correction	13
CD8α Structural Domains Enhance GUCY2C CAR-T Cell Efficacy	13
CX43 down-regulation promotes cell aggressiveness and 5-fluorouracil-resistance by attenuating cell stiffness in colorectal carcinoma	13
HSF1 is involved in immunotherapeutic response through regulating APOJ/STAT3-mediated PD-L1 expression in hepatocellular carcinoma	13
PI3Kγ inhibition drives M1 macrophage differentiation and synergizes with PD-L1 blockade to improve survival in poorly immunogenic head and neck squamous cell carcinoma	13
Targeting mitochondrial tyrosyl-tRNA synthetase YARS2 suppresses colorectal cancer progression	12
Effect of extracellular vesicle ZNF280B derived from lung cancer stem cells on lung cancer progression	12
β-amino acid substitution in the SIINFEKL antigen alters immunological recognition	12
WYC-209 inhibited GC malignant progression by down-regulating WNT4 through RARα	12
CircSETD2 inhibits YAP1 by interaction with HuR during breast cancer progression	12
Agent-based modeling in cancer biomedicine: applications and tools for calibration and validation	11
Association between the IL1B-511 C>T polymorphism and the risk of hematologic malignancies: data from a meta-analysis	11
NCAPD2 promotes the progression of lung adenocarcinoma through an AKT/MDM2/E2F1 positive feedback loop	11

MGAT4EP promotes tumor progression and serves as a prognostic marker for breast cancer	11
The human microbiome and cancer: a diagnostic and therapeutic perspective	11
Repression of the SUMO-conjugating enzyme UBC9 is associated with lowered double minutes and reduced tumor progression	11
Salidroside inhibited the proliferation of gastric cancer cells through up-regulating tumor suppressor miR-1343-3p and down-regulating MAP3K6/MMP24 signal molecules	11
CircATP5C1 promotes triple-negative breast cancer progression by binding IGF2BP2 to modulate CSF-1 secretion	11
Fusobacterium nucleatum in tumors: from tumorigenesis to tumor metastasis and tumor resistance	11
Correction	11
MiR-18a-5p attenuates HER2-positive breast cancer development by regulating PI3K/AKT pathway	11
Establishment of a visualized mouse orthotopic xenograft model of nasopharyngeal carcinoma	11
Amino-truncated NOV expression and its correlation with clinicopathologic features, prognosis, metastasis, and chemoresistance in bladder cancer	10
Roles of TRPM channels in glioma	10
Identification of coilin in bone marrow as a potential neuroblastoma tumor progression marker transcriptionally regulated by MYCN	10
TP53AIP1 induce autophagy via the AKT/mTOR signaling pathway in the breast cancer cells	10
Angiotensin receptor blockade and stereotactic body radiation therapy for early stage lung cancer ARB & SBRT for early stage lung cancer	10
Influence of genetic polymorphisms in vascular endothelial-related genes on the clinical outcome of axitinib in patients with metastatic renal cell carcinoma	10
First-line treatments for KRAS-mutant non-small cell lung cancer: current state and future perspectives	10
M6A-mediated molecular patterns and tumor microenvironment infiltration characterization in nasopharyngeal carcinoma	10
Clinical significance of WT1 in the evaluation of therapeutic effect and prognosis of non-M3 acute myeloid leukemia	10
High-throughput screening identifies the activity of histone deacetylase inhibitors in patient-derived models of soft tissue sarcoma	10
Integrating DOI in T classification improves the predictive performance of laryngeal cancer staging	9
SLX1 silencing overcomes Olaparib resistance in metastatic castration-resistant prostate cancer by disrupting SLX4-mediated DNA repair complexes	9
Tumor-derived exosomal miR-1247-3p promotes angiogenesis in bladder cancer by targeting FOXO1	9
Knockdown of LINC00511 enhances radiosensitivity of lung adenocarcinoma via regulating miR-497-5p/SMAD3	9
Chaperonin containing TCP1 subunit 6A may activate Notch and Wnt pathways to facilitate the malignant behaviors and cancer stemness in oral squamous cell carcinoma	9
CD46 and CD59 inhibitors enhance complement-dependent cytotoxicity of anti-CD38 monoclonal antibodies daratumumab and isatuximab in multiple myeloma and other B-cell malignancy cells	9
Effects of combined radiotherapy with immune checkpoint blockade on immunological memory in luminal-like subtype murine bladder cancer model	9
Neuroendocrine gene subsets are uniquely dysregulated in prostate adenocarcinoma	9
Netrin-1 inducing antiapoptotic effect of acute myeloid leukemia cells in a concentration-dependent manner through the Unc-5 netrin receptor B-focal adhesion kinase axis	9
Knockdown of NDUFAF6 inhibits breast cancer progression via promoting mitophagy and apoptosis	9
Obesity reduced survival with 5-fluorouracil and did not protect against chemotherapy-induced cachexia or immune cell cytotoxicity in mice	9
BRG1 promotes liver cancer cell proliferation and metastasis by enhancing mitochondrial function and ATP5A1 synthesis through TOMM40	9
RSK4 promotes the metastasis of clear cell renal cell carcinoma by activating RUNX1-mediated angiogenesis	8
IFN-γ downregulates miR-4319 to enhance NLRC5 and MHC-I expression in MHC-I-deficient breast cancer cells	8
Extracellular vesicle-packaged miR-4253 secreted by cancer-associated fibroblasts facilitates cell proliferation in gastric cancer by inducing macrophage M2 polarization	8
The antipsychotic drug pimozide promotes apoptosis through the RAF/ERK pathway and enhances autophagy in breast cancer cells	8
VAMP8 suppresses the metastasis via DDX5/β-catenin signal pathway in osteosarcoma	8
Cyclophilin A: promising target in cancer therapy	8
USP44 promotes chemotherapeutic drug resistance of triple negative breast cancer through EZH2 protein stability	8
Combination of metformin/efavirenz/fluoxetine exhibits profound anticancer activity via a cancer cell-specific ROS amplification	8
Exosomal miR-122-5p for regulation of secretory functions of fibroblasts and promotion of breast cancer metastasis by targeting MKP-2: an experimental study	8
Real-world efficacy of Bruton tyrosine kinase inhibitor based maintenance therapy in diffuse large B-cell lymphoma: a multicenter retrospective cohort study with external historical control	8
S-1-based concurrent chemoradiotherapy plus nimotuzumab in patients with locally advanced esophageal squamous cell carcinoma who failed neoadjuvant therapy: a real-world prospective study	8
Targeting CDK9 with selective inhibitors or degraders in tumor therapy: an overview of recent developments	8
The correlation between serum bone metabolism indexes and bone disease and survival in newly diagnosed multiple myeloma patients	7
Statement of Retraction: Didox (A Novel Ribonucleotide Reductase Inhibitor) Overcomes bc.l-2 Mediated Radiation Resistance in Prostate Cancer Cell Line PC-3	7
P4HA2 promotes tumor progression and is transcriptionally regulated by SP1 in colorectal cancer	7
The polymeric fluoropyrimidine CF10 overcomes limitations of 5-FU in pancreatic ductal adenocarcinoma cells through increased replication stress	7
Deep and lasting response and acquired resistance to BRAFV600E targeting in a low-grade ovarian cancer patient	7
RVd and CyBorD therapies remodel B-cell maturation signaling and alter immune and clonal architecture in multiple myeloma	7
The prognostic marker KRT81 is involved in suppressing CD8 + T cells and predicts immunotherapy response for triple-negative breast cancer	7
PSMD12 promotes the activation of the MEK-ERK pathway by upregulating KIF15 to promote the malignant progression of liver cancer	7
Fractionated radiotherapy initiated at the early stage of bone metastasis is effective to prolong survival in mouse model	7
METTL14 decreases FTH1 mRNA stability via m6A methylation to promote sorafenib-induced ferroptosis of cervical cancer	7
NAALADL2-AS2 functions as a competing endogenous RNA to regulate apoptosis and drug resistance in DLBCL	7
The efficacy of induction chemotherapy or adjuvant chemotherapy added to concurrent chemoradiotherapy in T3-4N0-1M0 nasopharyngeal carcinoma: a propensity score-matched analysis	7
Analysis of neuroglia and immune cells in the tumor microenvironment of breast cancer brain metastasis	7
BMSC-derived exosomal lncRNA PTENP1 suppresses the malignant phenotypes of bladder cancer by upregulating SCARA5 expression	7
Role of glutaminyl-peptide cyclotransferase in breast cancer doxorubicin sensitivity	7
Drug repurposing based on differentially expressed genes suggests drug combinations with possible synergistic effects in treatment of lung adenocarcinoma	7
Electrochemical biosensing in oncology: a review advancements and prospects for cancer diagnosis	7
MiR-135a-3p inhibits the progression of prostate cancer by targeting TLR4	7
Mutually exclusive teams-like patterns of gene regulation characterize phenotypic heterogeneity along the noradrenergic-mesenchymal axis in neuroblastoma	7
Epigenetic silencing ZSCAN23 promotes pancreatic cancer growth by activating Wnt signaling	6
N6-methyladenosine-regulated ADIRF impairs lung adenocarcinoma metastasis and serves as a potential prognostic biomarker	6
Lipopolysaccharide (LPS) stimulation of Pancreatic Ductal Adenocarcinoma (PDAC) and macrophages activates the NLRP3 inflammasome that influences the levels of pro-inflammatory cytokines in a co-cultur	6
CAFs-derived small extracellular vesicles circN4BP2L2 promotes proliferation and metastasis of colorectal cancer via miR-664b-3p/HMGB3 pathway	6
Upregulation of TTYH3 by lncRNA LUCAT1 through interacting with ALYREF facilitates the metastasis in non-small cell lung cancer	6
NAT10 promotes the tumorigenesis and progression of laryngeal squamous cell carcinoma through ac4C modification of FOXM1 mRNA	6
Toll-like receptor 4 inhibition sensitizes non-small cell lung cancer to radiotherapy	6
A study on metabolic characteristics and metabolic markers of gastrointestinal tumors	6
Targeting the IKZF1/BCL-2 axis as a novel therapeutic strategy for treating acute T-cell lymphoblastic leukemia	6
Patient-derived organoids (PDOs) as a promising platform for personalized treatment of colorectal cancer: current applications and future challenges	6
Correction	6
Ruangan Lidan decoction inhibits the growth and metastasis of liver cancer by downregulating miR-9-5p and upregulating PDK4	6
Ras interacting protein 1 facilitated proliferation and invasion of diffuse large B-cell lymphoma cells	6
Carcinoma-associated fibroblasts release microRNA-331-3p containing extracellular vesicles to exacerbate the development of pancreatic cancer via the SCARA5-FAK axis	6
Caspase 3-specific cleavage of ubiquitin-specific peptidase 48 enhances drug-induced apoptosis in AML	6
NVP-2, in combination with Orlistat, represents a promising therapeutic strategy for acute myeloid leukemia	6
POLE2 silencing inhibits the progression of colorectal carcinoma cells via wnt signaling axis	6
Molecular features, biological behaviors and clinical implications of m 5 C RNA methylation modification regulators in gastrointestinal cancers	6

PLK4 inhibitor exhibits antitumor effect and synergizes sorafenib via arresting cell cycle and inactivating Wnt/β-catenin pathway in anaplastic thyroid cancer	6
hsa_circ_0020378 regulating miR-339-3p/COL1A1 promotes osteosarcoma progression	6
EGR1/ LINC00839 /SOX5 axis modulates migration, invasion and Gemcitabine resistance of bladder cancer cells	6
RND1 inhibits epithelial-mesenchymal transition and temozolomide resistance of glioblastoma via AKT/GSK3-β pathway	6
Assessing progesterone receptor modulation in glioblastoma: from in vitro and animal model to a human pilot protocol	5
PCK2 promotes invasion and epithelial-to-mesenchymal transition in triple-negative breast cancer by promoting TGF-β/SMAD3 signaling through inhibiting TRIM67-mediated SMAD3 ubiquiti	5
Unraveling the dual role of METTL3-mediated m 6 A RNA modification in bladder cancer: mechanisms, therapeutic vulnerabilities, and clinical implications	5
SHR-1806, a robust OX40 agonist to promote T cell-mediated antitumor immunity	5
UCHL5 suppresses thyroid carcinoma progression via ZRANB1 stabilization and ferroptosis regulation	5
Genomic profiling, prognosis, and potential interventional targets in young and old patients with cholangiocarcinoma	5
Sinapine thiocyanate exhibited anti-colorectal cancer effects by inhibiting KRT6A/S100A2 axis	5
SHOC2 mediates the drug-resistance of triple-negative breast cancer cells to everolimus	5
PINCH-1 promotes tumor growth and metastasis by enhancing DRP1-mediated mitochondrial fission in head and neck squamous cell carcinoma	5
Arntl-induced upregulation of DUSP1 inhibits tumor progression in esophageal squamous cell carcinoma by inactivating ERK signaling	5
LncRNA DUXAP8 induces breast cancer radioresistance by modulating the PI3K/AKT/mTOR pathway and the EZH2-E-cadherin/RHOB pathway	5
Association between the apoptotic effect of Cabazitaxel and its pro-oxidant efficacy on the redox adaptation mechanisms in prostate cancer cells with different resistance phenotypes	5
BTF3 promotes proliferation and glycolysis in hepatocellular carcinoma by regulating GLUT1	5
A novel dopamine receptor D2 antagonist (ONC206) potentiates the effects of olaparib in endometrial cancer	5
Exosome-transmitted hsa_circ_0012634 suppresses pancreatic ductal adenocarcinoma progression through regulating miR-147b/HIPK2 axis	5
A pan-cancer analysis of MARCH8: molecular characteristics, clinical relevance, and immuno-oncology features	5
STEAP2 promotes osteosarcoma progression by inducing epithelial–mesenchymal transition via the PI3K/AKT/mTOR signaling pathway and is regulated by EFEMP2	5
Correction	5
The predictors of lymphopenia and its effects on survival in locally advanced esophageal squamous cell carcinoma	5
HSPB8-BAG3 chaperone complex modulates cell invasion in intrahepatic cholangiocarcinoma by regulating CASA-mediated Filamin A degradation	5
Functional validation of somatic variability in TP53 and KRAS for prediction of platinum sensitivity and prognosis in epithelial ovarian c	5
Correction	5
KLF7 enhances the invasion and migration of colorectal cancer cells via the miR-139-5p/TPD52 axis	5
MOICS, a novel classier deciphering immune heterogeneity and aid precise management of clear cell renal cell carcinoma at multiomics level	5
Targeting endoplasmic reticulum associated degradation pathway combined with radiotherapy enhances the immunogenicity of esophageal cancer cells	5
KLF4 targets RAB26 and decreases 5-FU resistance through inhibiting autophagy in colon cancer	5