OOIR: Observatory of International Research

Papers

(The TQCC of Vascular Pharmacology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
The transfer of gut microbiota/metabolites from children to mice affects cardiometabolic development and induces sex-dimorphism in recipients	86
Prevalence of antiphospholipid antibodies in COVID-19 patients: A meta-analysis	52
Graphical abstract TOC	43
Graphical abstract TOC	35
Therapy and guideline adherence at a multidisciplinary hypertension clinic: A prospective, observational study	34
Corrigendum to “Elucidating the crosstalk between endothelial-to-mesenchymal transition (EndoMT) and endothelial autophagy in the pathogenesis of atherosclerosis” [Vascular Pharmacology 155 (2024) 107	31
Patterns of medication use and potential drug-drug interactions in post-PCI patients: A study from Iran	31
The MEK-ERK-Egr-1 axis and its regulation in cardiovascular disease	28
Molecular mechanisms of flavonoids in myocardial ischemia reperfusion injury: Evidence from in-vitro and in-vivo studies	25
ASPYRE-1 study: An Italian multicenter prospective study on pulmonary hypertension modality of death and validation of REVEAL risk score	25
Biobanks: The unmet need in heart failure management	24
Animal experimental models of ischemic limbs – A systematic review	24
Prevention of cardiovascular complications in elderly cancer patients	23
Editorial Board	21
Editorial Board	21
Diabetes and vascular disease: New therapeutic avenues	20
Doxorubicin-induced cardiotoxicity enhance SARS-CoV-2 infection susceptibility in human cardiomyocytes	20
A random shuffle method to expand a narrow dataset: A heart failure cohort example	20
Optical stimulation of endothelial colony forming cells plated on light-sensitive conjugated polymers induces a TRPV1-mediated increase in intracellular Ca2+ concentration	19
Exploiting endothelial functions in bone regenerative medicine	19
Interaction of FOXO1 and SUMOylated PPARγ1 induced by hyperlipidemia and hyperglycemia favors vascular endothelial insulin resistance and dysfunction	18
MicroRNAs and their regulators: Potential therapeutic targets in pulmonary arterial hypertension	18
Changes in arterial myocyte excitability induced by subarachnoid hemorrhage in a rat model	18
Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease	18
The future of group 2 pulmonary hypertension: Exploring clinical trials and therapeutic targets	17

Lisosan G attenuates doxorubicin-induced injury in HUVEC cells: Antioxidant and sex-dependent autophagic responses	17
Short term action potential memory under heart failure conditions: An in silico study	17
Adipsin in the pathogenesis of cardiovascular diseases	16
Global and endothelial G-protein coupled receptor 75 (GPR75) knockout relaxes pulmonary artery and mitigates hypoxia-induced pulmonary hypertension	16
Hemodynamic markers: CFD-based prediction of cerebral aneurysm rupture risk	15
Nebivolol in the therapeutic landscape of heart failure: Mechanisms and clinical outcomes	15
A novel multidisciplinary approach in an LMNA-mutated patient: the importance of considering the overall clinical picture for the early diagnosis	14
Indobufen versus aspirin in patients with indication for antiplatelet therapy: A systematic review and meta-analysis	14
Circulating osteonectin predicts postural imbalance and cardiac dysfunction in heart failure	14
Graphical abstract TOC	14
Β-blockers activate autophagy on infantile hemangioma-derived endothelial cells in vitro	14
Graphical abstract TOC	14
Targeting the Ca2+ signaling toolkit as an alternative strategy to mitigate SARS-CoV-2-induced cardiovascular adverse events	14
The choice of the computational model impacts on the effects of the HCM-related MYBPc3 c772G->A mutation	13
Contents continued	13
Real-world observational study on pulmonary arterial hypertension: Italian cohort treated with macitentan and/or selexipag as a part of a combination treatment (INSPECTIO)	13
Novel NLRP3 inflammasome inhibitors INF150 and INF195 attenuate isoproterenol-induced hypertrophy in H9c2 rat cardiac myoblast	13
Graphical abstract TOC	12
Angina pectoris 2023: With and without obstructive coronary artery disease: Epidemiology, diagnosis, prognosis, and treatment	12
Dynamic co-culture of endothelial and smooth muscle cells as a platform for pathophysiological investigations of vascular calcifications	12
Sodium nitroprusside: A comprehensive systematic review of its role across various clinical settings	12
Trimethylamine N-oxide (TMAO) impact on endothelial dysfunction: An in vitro study using bovine aortic endothelial cells	12
Myocardial energy balance and metabolism as causes of myocardial ischemia	12
Therapeutic perspective on cardiomyopathy and heart failure in older adults through the lens of chronic inflammation	12
Brain natriuretic peptide as a potential predictor of hemorrhagic transformation in acute ischemic stroke patients with successful endovascular recanalization: A two-center retrospective cohort study	12
The use of specific antihypertensive medication and skin cancer risk: A systematic review of the literature and meta-analysis	12
Corrigendum to “Non-coding RNAs regulate angiogenic processes” [Vascular pharmacology 133–134 (2020) 106778]	12
The diverging roles of insulin-like growth factor binding proteins in pulmonary arterial hypertension	12
Additional therapeutic benefits of H2S-Donor combined with Dapagliflozin in a model of heart failure with preserved ejection fraction (HFpEF)	12
Interplay between CD28 and PD-1 in T cell immunotherapy	12
Editorial Board	11
Sexual dimorphism in aortic aneurysm: A review of the contributions of sex hormones and sex chromosomes	11
Bruton's Tyrosine Kinase inhibition by Acalabrutinib does not affect early or advanced atherosclerotic plaque size and morphology in Ldlr mice	11
Inflammation and the pathogenesis of atherosclerosis	11
Clinical characteristics and five-year outcomes in a prospective Russian real-world heart failure cohort	11
3-methoxycatechol causes vasodilation likely via KV channels: ex vivo, in silico docking and in vivo study	11
Clinical outcomes and safety of sotatercept in pulmonary arterial hypertension: A systematic review and meta-analysis of randomized controlled trials	11
A treatment algorithm for ischemic cardiomyopathy	10
Long-term dietary n3 fatty acid prevents aging-related cardiac diastolic and vascular dysfunction	10
Roles of endothelial and smooth muscle cell dysfunction and vasa vasorum in vasomotor disorders in ischemia with no obstructive coronary artery disease	10
The influence of environmental hypoxia on the goldfish (Carassius auratus) heart: From functional responses to mitochondrial molecular mechanisms	10
Istaroxime follow-on compounds: A new class of selective SERCA2a activators for chronic heart failure treatment	10
Resolvin D2 limits senescent cell accumulation in atherosclerotic plaques	10
Effects of simvastatin treatment on leptomeningeal collateral vessels: resistance, number and diameter	10
Zinc alpha 2-glycoprotein associates with features of plaque stability in patients with carotid atherosclerosis	10
The role of histone modifications in pulmonary hypertension: From mechanisms to therapeutic targets	10
Relevance of real-time analyzers to determine mitochondrial quality in endothelial cells and oxidative stress in preeclampsia	10
Comparative analysis of antiproliferative and vasodilator effects of drugs for pulmonary hypertension: Extensive in vitro study in rats and human	10
Cardiolipins dynamics during h-iPSC cardiomyocytes differentiation and end-stage failing heart condition	9
Empagliflozin protects H9c2 cardiomyoblasts from lipid-induced stress	9

Vascular diameter determines sensitivity to soluble guanylate cyclase activation in human mesenteric and renal arteries	9
Immune response following transcatheter aortic valve procedure	9
GYY4137, a hydrogen sulfide donor, protects against endothelial dysfunction in porcine coronary arteries exposed to myeloperoxidase and hypochlorous acid	9
Association of MMP9 with adverse features of plaque progression and residual inflammatory risk in patients with chronic coronary syndrome (CCS)	9
The chemokine receptor CXCR4 and its ligand CXCL12 (SDF-1) localize to ependymal cilia in brain ventricles	9
Advancements in non-invasive hyperspectral imaging: Mapping blood oxygen levels and vascular health for clinical and research applications	8
Bioactive lipids improve serum HDL and PON1 activities in coronary artery disease patients: Ex-vivo study	8
The selective deletion of tyrosyne hydroxylase gene in the endothelium affects cardiovascular function	8
N6-methyladenosine (m6A) post-transcriptional modification regulation of mRNA, an overlooked therapeutic opportunity to leverage mRNA processing in vascular smooth muscle cells	8
PI3KC2α: A novel key player in cardiac contractility and DOX-induced cardiotoxicity?	8
Amyloid-β: A potential mediator of aging-related vascular pathologies	8
Secondary multifactorial thrombotic microangiopathy revealing advanced HIV infection: A case report on endothelial dysfunction and estrogen therapy	8
Empagliflozin decreases ageing-associated arterial stiffening and vascular fibrosis under normoglycemic conditions	8
CaMKIIδ splice variants differentially regulate vascular smooth muscle cell motility	8
Catestatin as a key attenuator of cardiac inflammation in hypertension: Role of macrophage immunosuppression	8
Optimal medical therapy vs revascularization in chronic coronary syndromes: Does ISCHEMIA move the needle toward or away from revascularization??	8
MELAS syndrome: Insights into cardiac mechanics	8
Graphical abstract TOC	8
Plasma exosomes after PCI in non-diabetic STEMI patients fed barley beta-D-glucan-enriched pasta reduce oxidative stress-induced endothelial cell senescence	8
Multi-omics identification of quantitative trait loci associated with vascular pathogenesis and diagnostic potential in chronic venous disease	8
Editorial Board	8
The role of the endothelium in long COVID	8
Endothelial leptin receptor is dispensable for leptin-induced sympatho-activation and hypertension in male mice	8
Matrix metalloproteinases in aortic dissection	7
Sodium nitroprusside for advanced heart failure. A metanalysis of literature data	7
Effects of mavacamten in human myocardium from hypertrophic obstructive cardiomyopathy (HOCM) patients: A comparison with disopyramide	7
Is remote conditioning cardioprotection temperature dependent?	7
Stay connected: The myoendothelial junction proteins in vascular function and dysfunction	7
The life cycle of a capillary: Mechanisms of angiogenesis and rarefaction in microvascular physiology and pathologies	7
Graphical abstract TOC	7
Graphical abstract TOC	7
Editorial Board	7
A new perspective on lipid metabolism regulation to promote cardiac resilience to stress	7
Risk stratification of patients with SARS-CoV-2 by tissue factor expression in circulating extracellular vesicles	7
Untargeted metabolomic profiling reveals mTORC1-dependent regulation of amino acid utilization in lymphatic endothelial cells	7
From cine-MRI to computational models of blood flow within the heart	7
Extracellular stiffness as a determinant of cardiac dysfunction in Duchenne's muscular dystrophy: A study on human iPSC-derived cardiomyocytes	7
Exploring bradykinin: A common mediator in the pathophysiology of sepsis and atherosclerotic cardiovascular disease	7
iPSC-derived cardiac models for exploring MLIP function in LMNA cardiomyopathy	7
Emerging therapies in dyslipidaemias	6
Takotsubo: Profiling extracellular vesicles to reveal pathophysiology	6
Wavelet spectral analysis of microvascular blood flow during nociceptive and cognitive stimuli	6
Statin-mediated regulation of miRNA expression in circulating endothelial progenitor cells in hypertensive patients: A translational mechanism of vascular protection	6
The short-chain fatty acid butyrate accelerates vascular calcification via regulation of histone deacetylases and NF-κB signaling	6
Empagliflozin restores autophagy and attenuates ponatinib-induced cardiomyocyte senescence and death	6
Macrophage-mediated downregulation of lncRNA Carmn in mouse abdominal aortic aneurysm	6
Emerging role of the adaptive immunity in aortic aneurysm and dissection	6
Graphical abstract TOC	6
Optogenetic manipulation of cardiac electrical dynamics using sub-threshold illumination: Dissecting the role of cardiac alternans in terminating rapid rhythms	6
Development of an AI-based algorithm designed to model and predict temporal dynamics of heart rate variability (HRV)	6
Elucidating emerging signaling pathways driving endothelial dysfunction in cardiovascular aging	6
Apoptosis signal-regulating kinase-1 regulates thrombin-induced endothelial permeability	5
Frataxin deficiency disrupts mitochondrial respiration and pulmonary endothelial cell function	5
Different gene expression patterns between mouse and human brain pericytes revealed by single-cell/nucleus RNA sequencing	5
Contents continued	5
Platelet modulation in cardiac ischemia/reperfusion injury: Functional impact of ADP, high glucose and NLRP3 inhibition	5
Graphical abstract TOC	5
An intrinsic mechanism of metabolic resilience influences the cardiac response to stress	5
Telomere dysfunction, vascular aging, and acute coronary syndrome: Clinical insights and the role of PM10 exposure	5
An AI and Statistical Shape Analysis combined framework to extract features in complex cardiovascular structures	5