Molecular & Cellular Proteomics

Papers
(The TQCC of Molecular & Cellular Proteomics is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
In-Cell Chemical Crosslinking Identifies Hotspots for SQSTM-1/p62-IκBα Interaction That Underscore a Critical Role of p62 in Limiting NF-κB Activation Through IκBα Stabilization155
Proteomic Characterization of Acute Myeloid Leukemia for Precision Medicine131
LC-SRM Combined With Machine Learning Enables Fast Identification and Quantification of Bacterial Pathogens in Urinary Tract Infections112
CREB-Regulated Transcriptional Coactivator 2 Proteome Landscape is Modulated by SREBF177
Clinical Proteomics for Solid Organ Tissues69
Integrative Proteogenomics for Differential Expression and Splicing Variation in a DM1 Mouse Model66
Exploring the Early Molecular Pathogenesis of Osteoarthritis Using Differential Network Analysis of Human Synovial Fluid56
Metabolic Enzyme Alterations and Astrocyte Dysfunction in a Murine Model of Alexander Disease With Severe Reactive Gliosis53
A Multipathway Phosphopeptide Standard for Rapid Phosphoproteomics Assay Development53
Quantitative Proteomic Analysis Reveals Functional Alterations of the Peripheral Immune System in Colorectal Cancer52
Region and cell-type resolved multi-omic altas of the heart48
Nuclear Factor I Family Members are Key Transcription Factors Regulating Gene Expression48
Differential Proteome and Interactome Analysis Reveal the Basis of Pleiotropy Associated With the Histidine Methyltransferase Hpm1p44
Table of Contents43
PROTEOMIC CHANGES TO THE ANTERIOR CEREBRAL ARTERY IN ALZHEIMER’S DISEASE43
Easier, More Robust, and Faster Low-flow Quantitative Proteomics Approach40
Prenylated PALM2 Promotes the Migration of Esophageal Squamous Cell Carcinoma Cells Through Activating Ezrin37
Immunopeptidomic Analyses of Colorectal Cancers With and Without Microsatellite Instability37
CellEKT: a robust chemical proteomics workflow to profile cellular target engagement of kinase inhibitors36
Discovery Proteomics Analysis Determines That Driver Oncogenes Suppress Antiviral Defense Pathways Through Reduction in Interferon-β Autocrine Stimulation35
Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides34
The rise of molecular glues and bifunctional compounds33
Developing Cross-linking Mass Spectrometry to Define Protein Interaction Landscapes33
WITHDRAWN32
High-throughput subcellular proteomics reveals phospho-signaling dynamics31
PRM-LIVE Accelerates Target Class-based Selectivity Profiling of Small Molecule Inhibitors30
Toward Comprehensive, Single-molecule Proteomics: Protein Identification by Shortepitope Mapping29
Proteogenomic analyses of CRISPR inhibited expression of a panel genes associated with Alzheimer's disease and related dementias in iPSC-derived neurons using a fully automated workflow29
In Situ Cell-Surface Proteomics: Method Development and Applications in Neurobiology28
Recent Advances in Mass Spectrometry-Based Protein Interactome Studies28
Proteomics, Transcriptomics, and Phosphoproteomics Reveal the Mechanism of Talaroconvolutin-A Suppressing Bladder Cancer via Blocking Cell Cycle and Triggering Ferroptosis27
A Peptidisc-Based Survey of the Plasma Membrane Proteome of a Mammalian Cell27
A Proteomic Approach Identifies Isoform-Specific and Nucleotide-Dependent RAS Interactions26
Bridging the Gap From Proteomics Technology to Clinical Application: Highlights From the 68th Benzon Foundation Symposium26
Proteomic Diversity in Bacteria: Insights and Implications for Bacterial Identification26
DIA-Based Phosphoproteomics Identifies Early Phosphorylation Events in Response to EGTA and Mannitol in Arabidopsis25
HEXB Drives Raised Paucimannosylation in Colorectal Cancer and Stratifies Patient Risk25
Deep Learning Prediction Boosts Phosphoproteomics-Based Discoveries Through Improved Phosphopeptide Identification24
Degradomic Identification of Membrane Type 1-Matrix Metalloproteinase as an ADAMTS9 and ADAMTS20 Substrate24
Development of a Fit-For-Purpose Multi-Marker Panel for Early Diagnosis of Pancreatic Ductal Adenocarcinoma24
Proteomics Profiling of Human Synovial Fluid Suggests Increased Protein Interplay in Early-Osteoarthritis (OA) That Is Lost in Late-Stage OA24
The Acyl-Proteome of Syntrophus aciditrophicus Reveals Metabolic Relationships in Benzoate Degradation24
Phosphoproteome Analysis Identifies a Synaptotagmin-1-Associated Complex Involved in Ischemic Neuron Injury23
Integrative Proteomics and N-Glycoproteomics Analyses of Rheumatoid Arthritis Synovium Reveal Immune-Associated Glycopeptides22
Filter-Aided Extracellular Vesicle Enrichment (FAEVEr) for Proteomics22
Cerebrospinal Fluid Protein Markers Indicate Neuro-Damage in SARS-CoV-2-Infected Nonhuman Primates21
Proteins in Tumor-Derived Plasma Extracellular Vesicles Indicate Tumor Origin21
Dynamic Proteomic Changes in Tumor and Immune Organs Reveal Systemic Immune Response to Tumor Development21
Assessment of Kinome-Wide Activity Remodeling upon Picornavirus Infection20
Phosphoproteome Profiling of the Receptor Tyrosine Kinase MuSK Identifies Tyrosine Phosphorylation of Rab GTPases20
The in vivo Interaction Landscape of Histones H3.1 and H3.320
Improved Mass Spectrometry–Based Methods Reveal Abundant Propionylation and Tissue-Specific Histone Propionylation Profiles20
Real-Time Search-Assisted Acquisition on a Tribrid Mass Spectrometer Improves Coverage in Multiplexed Single-Cell Proteomics20
Enhanced In Situ Spatial Proteomics by Effective Combination of MALDI Imaging and LC-MS/MS19
Relative Quantification of Proteins in Formalin-Fixed Paraffin-Embedded Breast Cancer Tissue Using Multiplexed Mass Spectrometry Assays19
(Sialyl)Lewis Antigen Expression on Glycosphingolipids, N-, and O-Glycans in Colorectal Cancer Cell Lines is Linked to a Colon-Like Differentiation Program19
TIMAHAC: Streamlined Tandem IMAC-HILIC Workflow for Simultaneous and High-Throughput Plant Phosphoproteomics and N-glycoproteomics19
Multi-Omics Analysis Unveils Nsun5-Mediated Molecular Alterations in the Somatosensory Cortex and Its Impact on Pain Sensation18
Multi-nanoparticle Workflow Enables Deep Plasma Proteomics at Scale, with Enhanced Precision, and Depths of Coverage18
Proteomic Identification of Autophagy Cargo Using Novel Tools in Combination with Quantitative Proteomics.18
Highly multiplexed proteome-wide quantitation of functional residues enabled by a novel 11plex-AzidoTMT reagent18
Mapping diverse proteome responses with intelligent mass spectrometry18
Prospective on Imaging Mass Spectrometry in Clinical Diagnostics18
Highly multiplexed label-free imaging of tissue proteoforms using individual ion mass spectrometry18
The One Hour Human Proteome18
Mass spectrometry and SomaScan technologies to detect a plasma copper proteome in two human populations18
Automated workflows for DIA data using DIA-NN on the PaSER platform18
The Role of Clinical Glyco(proteo)mics in Precision Medicine18
In-Depth Analysis of miRNA Binding Sites Reveals the Complex Response of Uterine Epithelium to miR-26a-5p and miR-125b-5p During Early Pregnancy17
Back Cover17
A Time Point Proteomic Analysis Reveals Protein Dynamics of Plasmodium Oocysts17
Computational challenges of identification and quantification algorithms in single-cell proteomic data.17
Generation of a Deep Mouse Brain Spectral Library for Transmembrane Proteome Profiling in Mental Disease Models16
Three-dimensional feature matching improves the sensitivity of single-cell and spatial proteomics16
Clinical Proteomics: A Promise Becoming Reality16
Cover16
Deciphering the highly complex cancer immunopeptidome16
pXg: Comprehensive Identification of Noncanonical MHC-I–Associated Peptides From De Novo Peptide Sequencing Using RNA-Seq Reads16
Mapping the Degradable Kinome: A Resource for Expedited Degrader Development16
Yellow Fever Blood Proteomics Study by Trapped Ion Mobility Mass Spectrometry16
Improving the Depth and Reliability of Glycopeptide Identification Using Protein Prospector15
11th Asia Oceania Human Proteome Organization Congress Report15
Probing the sORF-Encoded Peptides of Deinococcus radiodurans in Response to Extreme Stress15
Cover14
Multiomic Metabolic Enrichment Network Analysis Reveals Metabolite–Protein Physical Interaction Subnetworks Altered in Cancer14
Integrated Immunopeptidomics and Proteomics Study of SARS-CoV-2–Infected Calu-3 Cells Reveals Dynamic Changes in Allele-specific HLA Abundance and Antigen Presentation14
TEAD Proteins Associate With DNA Repair Proteins to Facilitate Cellular Recovery From DNA Damage14
Chemical Proteomics Reveals Nε-Fatty-Acylation of Septins by Rho Inactivation Domain (RID) of the Vibrio MARTX Toxin to Alter Septin Localization and Organization14
MhcVizPipe: A Quality Control Software for Rapid Assessment of Small- to Large-Scale Immunopeptidome Datasets14
Deciphering Spatial Protein–Protein Interactions in Brain Using Proximity Labeling14
Protein Kinase Signaling Networks Driven by Oncogenic Gq/11 in Uveal Melanoma Identified by Phosphoproteomic and Bioinformatic Analyses14
Elucidating Fibroblast Growth Factor–Induced Kinome Dynamics Using Targeted Mass Spectrometry and Dynamic Modeling14
Causal Inference and Annotation of Phosphoproteomics Data in Multiomics Cancer Studies13
Cover13
SIRT3 functions as an eraser of histone H3K9 lactylation to modulate transcription for inhibiting the progression of esophageal cancer13
A New Monoclonal Antibody Enables BAR Analysis of Subcellular Importin β1 Interactomes13
Deep Learning Enhances Precision of Citrullination Identification in Human and Plant Tissue Proteomes13
Combining Data Independent Acquisition With Spike-In SILAC (DIA-SiS) Improves Proteome Coverage and Quantification13
Phosphorylation Dynamics in a flg22-Induced, G Protein–Dependent Network Reveals the AtRGS1 Phosphatase12
Uncommon N-Glycan Structures in Anhydrobiotic Tardigrades12
Application of stable isotope labelingbased quantitative PTM proteomics and interactomics in study of Arabidopsis cell signaling12
Complexome profiling of mitochondrial oxidative phosphorylation knockout models.12
Landscape of steroid dynamics in pregnancy - insights from the maternal-placental-fetal unit and placental models12
Phosphoproteomic Analysis of FLCN Inactivation Highlights Differential Kinase Pathways and Regulatory TFEB Phosphoserines12
Localized K63 Ubiquitin Signaling Is Regulated by VCP/p97 During Oxidative Stress12
Early Life Exposure to Deltamethrin Impairs Synaptic Function by Altering the Brain-Derived Extracellular Vesicle Proteome12
Tracking drug action at the cell surface and the secreted proteome12
msqrob2PTM: Differential Abundance and Differential Usage Analysis of MS-Based Proteomics Data at the Posttranslational Modification and Peptidoform Level12
Quantification and Proteomic Characterization of β-Hydroxybutyrylation Modification in the Hearts of AMPKα2 Knockout Mice12
Large-Scale Plasma Proteome Epitome Profiling is an Efficient Tool for the Discovery of Cancer Biomarkers12
WITHDRAWN12
Trypanosoma cruzi cardiomyocyte infection promotes innate immune response and metabolic rewiring12
Proteogenomic Analysis of Breast Cancer Transcriptomic and Proteomic Data, Using De Novo Transcript Assembly: Genome-Wide Identification of Novel Peptides and Clinical Implications12
Robust and accurate redox metabolomics and proteomics of clinical samples by in situ derivatization of free thiols11
WITHDRAWN11
Evaluating timsTOF Pro 2 for the analysis of histone PTMs measured in Global Chromatin Profiling using dia-PASEF and prm-PASEF11
Sulconazole Induces PANoptosis by Triggering Oxidative Stress and Inhibiting Glycolysis to Increase Radiosensitivity in Esophageal Cancer11
WITHDRAWN11
Antibody-based enrichment of phosphotyrosine peptides using magnetic beads simplifies and outperforms results obtained using Protein A agarose beads11
An Automated Nanowell-Array Workflow for Quantitative Multiplexed Single-Cell Proteomics Sample Preparation at High Sensitivity11
Analyzing N-Glycosylation Biosynthetic Networks Using Mass Spectrometry11
Experience-Induced Remodeling of the Hippocampal Post-synaptic Proteome and Phosphoproteome11
Serum Exosomes From Epithelial Ovarian Cancer Patients Contain LRP1, Which Promotes the Migration of Epithelial Ovarian Cancer Cell10
Cover10
Single Cell Proteomics Reveals Specific Cellular Subtypes in Cardiomyocytes Derived from Human iPSCs and Adult Hearts10
Exploration of Nitrotyrosine-Containing Proteins and Peptides by Antibody-Based Enrichment Strategies10
Application of Liquid-Liquid Extraction for N-terminal Myristoylation Proteomics10
Antibody Profiling of Pan-Cancer Viral Proteome Reveals Biomarkers for Nasopharyngeal Carcinoma Diagnosis and Prognosis10
Comparative Proteome and Cis-Regulatory Element Analysis Reveals Specific Molecular Pathways Conserved in Dog and Human Brains10
GRable Version 1.0: A Software Tool for Site-Specific Glycoform Analysis With Improved MS1-Based Glycopeptide Detection With Parallel Clustering and Confidence Evaluation With MS2 Information10
Integrated Proteomics to Understand the Role of Neuritin (NRN1) as a Mediator of Cognitive Resilience to Alzheimer’s Disease10
Exploring the Spatial Landscape of the Estrogen Receptor Proximal Proteome With Antibody-Based Proximity Labeling10
Bioinertization of NanoLC/MS/MS Systems by Depleting Metal Ions From the Mobile Phases for Phosphoproteomics10
Insight Into the Dynamics of the Ixodes ricinus Nymphal Midgut Proteome10
Galectin-4 Antimicrobial Activity Primarily Occurs Through its C-Terminal Domain10
Challenges and Opportunities for Single-cell Computational Proteomics10
Mass Spectrometry–Driven Discovery of Neuropeptides Mediating Nictation Behavior of Nematodes10
A Proteogenomic Pipeline for the Analysis of Protein Biosynthesis Errors in the Human Pathogen Candida albicans10
inSPIRE: An Open-Source Tool for Increased Mass Spectrometry Identification Rates Using Prosit Spectral Prediction10
Cover10
The Proteome of Large or Small Extracellular Vesicles in Pig Seminal Plasma Differs, Defining Sources and Biological Functions10
Predicting Protein Pathways Associated to Tumor Heterogeneity by Correlating Spatial Lipidomics and Proteomics: The Dry Proteomic Concept10
Proteome Mapping of the Human Pancreatic Islet Microenvironment Reveals Endocrine–Exocrine Signaling Sphere of Influence10
The Proteome and Phosphoproteome Uncovers Candidate Proteins Associated With Vacuolar Phosphate Signal Multipled by Vacuolar Phosphate Transporter 1 (VPT1) in Arabidopsis9
Cover9
Post-translational Modifications and Their Effects on the Conformation and Function of Hsp90 in Embryonic Stem Cells9
Integrated Multiomics Reveals Alterations in Paucimannose and Complex Type N-Glycans in Cardiac Tissue of Patients with COVID-199
Ciliopathy-Associated Missense Mutations in IFT140 are Tolerated by the Inherent Resilience of the IFT Machinery9
Super Enhanced Purification of Denatured-Refolded Ubiquitinated Proteins by ThUBD Revealed Ubiquitinome Dysfunction in Liver Fibrosis9
Unified Workflow for the Rapid and In-Depth Characterization of Bacterial Proteomes9
Editorial Board9
WITHDRAWN9
Early Proteomic Characteristics and Changes in the Optic Nerve Head, Optic Nerve, and Retina in a Rat Model of Ocular Hypertension9
Innovations Toward Immunopeptidomics9
Profiling Proteins and Phosphorylation Sites During T Cell Activation Using an Integrated Thermal Shift Assay9
Immunopeptidomics Mapping of Listeria monocytogenes T Cell Epitopes in Mice9
An AI-driven leap forward in peptide identification through deconvolution of chimeric spectra9
Cover9
Insights Into Glycobiology and the Protein-Glycan Interactome Using Glycan Microarray Technologies9
Spatial Proteomics Reveals Differences in the Cellular Architecture of Antibody-Producing CHO and Plasma Cell–Derived Cells9
Harmonizing Labeling and Analytical Strategies to Obtain Protein Turnover Rates in Intact Adult Animals9
Proteomic Characterization of Renal Cell Carcinoma Using MALDI-MS Imaging8
Proteogenomic analysis of multiple myeloma reveals therapeutic opportunities and predictive signatures8
MSFragger-Labile: A Flexible Method to Improve Labile PTM Analysis in Proteomics8
Impact of Bmal1 Rescue and Time-Restricted Feeding on Liver and Muscle Proteomes During the Active Phase in Mice8
Proteomics and β-hydroxybutyrylation Modification Characterization in the Hearts of Naturally Senescent Mice8
ZASP: A Highly Compatible and Sensitive ZnCl2 Precipitation-Assisted Sample Preparation Method for Proteomic Analysis8
Proteomic Analysis Reveals Trilaciclib-Induced Senescence8
Intelligent Data Acquisition Approaches for Single Cell Proteomics8
WITHDRAWN8
An improved method for sampling and quantitative protein analytics of cerebrospinal fluid of individual mice8
iProPhos: A Web-Based Interactive Platform for Integrated Proteome and Phosphoproteome Analysis8
Inducible Protein Degradation as a Strategy to Identify Phosphoprotein Phosphatase 6 Substrates in RAS-Mutant Colorectal Cancer Cells8
Corrigendum for “Mass Spectrometry-Based Proteomics Analysis of Human Substantia Nigra From Parkinson's Disease Patients Identifies Multiple Pathways Potentially Involved in the Disease”8
BAMS: A Robust Analytical Platform for Quantifying Histone Modifications and Various Proteoforms by IP MALDI MS8
Early Days in the Hunt Laboratory at UVA, 1969 to 19808
Proteome imaging of human pancreas with a novel microPOTS platform8
An Introduction to Analytical Challenges, Approaches, and Applications in Mass Spectrometry–Based Secretomics8
Correction: Dynamic Changes to the Skeletal Muscle Proteome and Ubiquitinome Induced by the E3 Ligase, ASB2β8
Change in Publication Schedule8
Immune Checkpoint Blockade Augments Changes Within Oncolytic Virus-induced Cancer MHC-I Peptidome, Creating Novel Antitumor CD8 T Cell Reactivities8
eEF2K Activity Determines Synergy to Cotreatment of Cancer Cells With PI3K and MEK Inhibitors8
MSstatsPTM: Statistical Relative Quantification of Posttranslational Modifications in Bottom-Up Mass Spectrometry-Based Proteomics7
Identification of State-Specific Proteomic and Transcriptomic Signatures of Microglia-Derived Extracellular Vesicles7
From Patient Skin to Brain: Understanding Neurodegeneration with Fibroblast-iPSCNeuron Proteomics7
Single-Cell Proteomic Characterization of Drug-Resistant Prostate Cancer Cells Reveals Molecular Signatures Associated with Morphological Changes7
Native Size-Exclusion Chromatography–Based Mass Spectrometry Reveals New Components of the Early Heat Shock Protein 90 Inhibition Response Among Limited Global Changes7
Characterization of Glycoproteoforms of Integrins α2 and β1 in Megakaryocytes in the Occurrence of JAK2V617F Mutation-Induced Primary Myelofibrosis7
Development of a Spectral Library for the Discovery of Altered Genomic Events in Mycobacterium avium Associated With Virulence Using Mass Spectrometry–Based Proteogenomic Analysis7
diaPASEF Analysis for HLA-I Peptides Enables Quantification of Common Cancer Neoantigens7
Multiomic Analysis Reveals Disruption of Cholesterol Homeostasis by Cannabidiol in Human Cell Lines7
Cover7
Biomarkers Found in the Tumor Interstitial Fluid may Help Explain the Differential Behavior Among Keratinocyte Carcinomas7
SpotLight Proteomics Identifies Variable Sequences of Blood Antibodies Specific Against Deamidated Human Serum Albumin7
Proteomic and Cellular Characterization of Omicron Breakthrough Infections and a Third Homologous or Heterologous Boosting Vaccination in a Longitudinal Cohort7
Proteomic Profiling of Muscular Adaptations to Short-Term Concentric Versus Eccentric Exercise Training in Humans7
STK33 Phosphorylates Fibrous Sheath Protein AKAP3/4 to Regulate Sperm Flagella Assembly in Spermiogenesis7
An Expanding Repertoire of Protein Acylations7
PI3Kα Translocation Mediates Nuclear PtdIns(3,4,5)P3 Effector Signaling in Colorectal Cancer7
Quantification Quality Control Emerges as a Crucial Factor to Enhance Single-Cell Proteomics Data Analysis7
Identification of Proteome-Based Immune Subtypes of Early Hepatocellular Carcinoma and Analysis of Potential Metabolic Drivers7
Navigating proteomics techniques for molecular profiling of clinical cancer cohorts7
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