Molecular & Cellular Proteomics

Papers
(The TQCC of Molecular & Cellular Proteomics is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)
ArticleCitations
Cover102
Isolation of proteins on chromatin (iPOC) reveals signaling pathway-dependent alterations in the DNA-bound proteome92
Quantitative Proteomic Analysis Reveals Functional Alterations of the Peripheral Immune System in Colorectal Cancer83
Multi-Omic Analysis of Esophageal Adenocarcinoma Uncovers Candidate Therapeutic Targets and Cancer-Selective Posttranscriptional Regulation61
Nuclear Factor I Family Members are Key Transcription Factors Regulating Gene Expression56
Global Proteomics Indicates Subcellular-Specific Anti-Ferroptotic Responses to Ionizing Radiation47
Quantitative chromatin protein dynamics during replication origin firing in human cells45
Cover43
Rapid and In-Depth Coverage of the (Phospho-)Proteome With Deep Libraries and Optimal Window Design for dia-PASEF36
Personalized Drug Therapy: Innovative Concept Guided With Proteoformics35
Molecular Signatures of Neurodegenerative Diseases Identified by Proteomic and Phosphoproteomic Analyses in Aging Mouse Brain34
Cover31
Unified Workflow for the Rapid and In-Depth Characterization of Bacterial Proteomes30
Cover29
The Urinary Proteomic Profile Implicates Key Regulators for Urologic Chronic Pelvic Pain Syndrome (UCPPS): A MAPP Research Network Study28
Increasing the coverage, throughput and accessibility of single-cell proteomics27
Identification of tumor antigens for cancer immunotherapy27
Table of Contents27
MS-based Detection of Pathogen Antigen Through Immunoprecipitation of Its Proteolytic Peptides26
Targeted LC/MRM-MS analysis of 60 biomarkers on the Health Surveillance Panel (HSP) and DIA analysis of matched venous whole blood, plasma and capillary whole blood collected on remote sampling device25
Proteomics of spatially identified tissues in whole organs24
A streamlined tandem tip-based workflow for sensitive nanoscale phosphoproteomics24
Increasing the Throughput of Activity-Based Proteome Profiling Studies with Real-Time Search and Sample Hyperplexing23
Easier, More Robust, and Faster Low-flow Quantitative Proteomics Approach22
Computational challenges of identification and quantification algorithms in single-cell proteomic data.22
Discovery of GSTZ1 as a novel target by using fully functionalized fragment-like probes and chemical proteomics22
PROTEOMIC CHANGES TO THE ANTERIOR CEREBRAL ARTERY IN ALZHEIMER’S DISEASE22
Distribution analysis of small metabolites on lens using sand-rose-like ZnO for imaging mass spectrometry21
Simultaneous quantification of GDF15 and IGFBP7 by LC-MS/MS for studies on hyperemesis gravidarum21
Defining the molecular basis of immune heterogeneity between individuals using immunoproteomics20
Chemoproteomic capture of RNA binding activity in living cells20
ETV6-NTRK3 oncofusion variant interactomes20
Post-Deconvolution MS/MS Spectra Extraction with Data-Independent Acquisition for Comprehensive Profiling of Urinary Conjugated Metabolome20
An Atlas of the Knee Joint Proteins and Their Role in Osteoarthritis Defined by Literature Mining19
The social architecture of an in-depth cellular protein interactome19
Proteomics Profiling Reveals the Molecular Signatures and Potential Therapeutic Targets of Human Nasopharyngeal Carcinoma18
Phosphorothioate RNA Analysis by NETD Tandem Mass Spectrometry18
New Global Insights on the Regulation of the Biphasic Life Cycle and Virulence Via ClpP-Dependent Proteolysis in Legionella pneumophila18
Comprehensive Glycomic and Proteomic Analysis of Mouse Striatum and Lateral Hypothalamus Following Repeated Exposures to Cocaine or Methamphetamine17
Cover17
High-Throughput Human Complement C3 N-Glycoprofiling Identifies Markers of Early Onset Type 1 Diabetes Mellitus in Children16
ProMetheusDB: An In-Depth Analysis of the High-Quality Human Methyl-proteome16
MHC Class I Immunopeptidome: Past, Present, and Future16
Deciphering Nucleic Acid Binding Proteome of Mouse Immune Organs Reveals Hub Proteins for Aging16
Functional Impact of Protein–RNA Variation in Clinical Cancer Analyses16
DIA-Based Proteomics Identifies IDH2 as a Targetable Regulator of Acquired Drug Resistance in Chronic Myeloid Leukemia15
FMRP Long-Range Transport and Degradation Are Mediated by Dynlrb1 in Sensory Neurons15
EGFR-T790M Mutation–Derived Interactome Rerouted EGFR Translocation Contributing to Gefitinib Resistance in Non-Small Cell Lung Cancer15
Analysis of the Healthy Platelet Proteome Identifies a New Form of Domain-Specific O-Fucosylation15
Hypoxia Is a Dominant Remodeler of the Effector T Cell Surface Proteome Relative to Activation and Regulatory T Cell Suppression15
High-Resolution Structural Proteomics of Mitochondria Using the ‘Build and Retrieve’ Methodology15
Integrative Proteomic Analysis Reveals the Cytoskeleton Regulation and Mitophagy Difference Between Ischemic Cardiomyopathy and Dilated Cardiomyopathy14
A Causal Model of Ion Interference Enables Assessment and Correction of Ratio Compression in Multiplex Proteomics14
Insight Into the Dynamics of the Ixodes ricinus Nymphal Midgut Proteome14
Tissue-Characteristic Expression of Mouse Proteome14
inSPIRE: An Open-Source Tool for Increased Mass Spectrometry Identification Rates Using Prosit Spectral Prediction13
Normics: Proteomic Normalization by Variance and Data-Inherent Correlation Structure13
Discovery Proteomics Analysis Determines That Driver Oncogenes Suppress Antiviral Defense Pathways Through Reduction in Interferon-β Autocrine Stimulation13
Targeted Dynamic Phospho-Proteogenomic Analysis of Gastric Cancer Cells Suggests Host Immunity Provides Survival Benefit13
The Hyperproliferation Mechanism of Cholesteatoma Based on Proteomics: SNCA Promotes Autophagy-Mediated Cell Proliferation Through the PI3K/AKT/CyclinD1 Signaling Pathway13
Biochemical Deconstruction and Reconstruction of Nuclear Matrix Reveals the Layers of Nuclear Organization13
In-Cell Chemical Crosslinking Identifies Hotspots for SQSTM-1/p62-IκBα Interaction That Underscore a Critical Role of p62 in Limiting NF-κB Activation Through IκBα Stabilization12
Glutamine-Fructose-6-Phosphate Transaminase 2 (GFPT2) Is Upregulated in Breast Epithelial–Mesenchymal Transition and Responds to Oxidative Stress12
Differential Proteome and Interactome Analysis Reveal the Basis of Pleiotropy Associated With the Histidine Methyltransferase Hpm1p12
Bioinertization of NanoLC/MS/MS Systems by Depleting Metal Ions From the Mobile Phases for Phosphoproteomics12
Integrative Proteogenomics for Differential Expression and Splicing Variation in a DM1 Mouse Model12
Application of Liquid-Liquid Extraction for N-terminal Myristoylation Proteomics11
The Role of Serine/Threonine-Specific Protein Kinases in Cyanobacteria - SpkB Is Involved in Acclimation to Fluctuating Conditions in Synechocystis sp. PCC 680311
An Integrated Approach to Protein Discovery and Detection From Complex Biofluids11
Exploration of Nitrotyrosine-Containing Proteins and Peptides by Antibody-Based Enrichment Strategies11
CREB-Regulated Transcriptional Coactivator 2 Proteome Landscape is Modulated by SREBF111
Metabolic Enzyme Alterations and Astrocyte Dysfunction in a Murine Model of Alexander Disease With Severe Reactive Gliosis11
Global Analysis of Post-Translational Side-Chain Arginylation Using Pan-Arginylation Antibodies11
The Quantitative Biotinylproteomics Studies Reveal a WInd-Related Kinase 1 (Raf-Like Kinase 36) Functioning as an Early Signaling Component in Wind-Induced Thigmomorphogenesis and Gravitropism11
An Automated and Fast Sample Preparation Workflow for Laser Microdissection Guided Ultrasensitive Proteomics10
Immunopeptidomic Analyses of Colorectal Cancers With and Without Microsatellite Instability10
A Multipathway Phosphopeptide Standard for Rapid Phosphoproteomics Assay Development10
metaExpertPro: A Computational Workflow for Metaproteomics Spectral Library Construction and Data-Independent Acquisition Mass Spectrometry Data Analysis10
Cellular Proteomic Profiling Using Proximity Labeling by TurboID-NES in Microglial and Neuronal Cell Lines10
Immunopeptidomics Mapping of Listeria monocytogenes T Cell Epitopes in Mice10
Cover10
Proteomic Analysis Reveals the Composition of Glutamatergic Organelles of Auditory Inner Hair Cells10
Integrated Liver and Plasma Proteomics in Obese Mice Reveals Complex Metabolic Regulation9
Integrated Application of Multiomics Strategies Provides Insights Into the Environmental Hypoxia Response in Pelteobagrus vachelli Muscle9
Methods to Discover and Validate Biofluid-Based Biomarkers in Neurodegenerative Dementias9
Clinical Proteomics for Solid Organ Tissues9
The Proteome of Large or Small Extracellular Vesicles in Pig Seminal Plasma Differs, Defining Sources and Biological Functions9
A Comparative Analysis of Data Analysis Tools for Data-Independent Acquisition Mass Spectrometry9
CySP3-96 enables scalable, streamlined, and low-cost sample preparation for cysteine chemoproteomic applications9
Proteomic Characterization of Acute Myeloid Leukemia for Precision Medicine9
Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides9
Prenylated PALM2 Promotes the Migration of Esophageal Squamous Cell Carcinoma Cells Through Activating Ezrin9
MS-Based Proteomics of Body Fluids: The End of the Beginning9
Secretome Analysis: Reading Cellular Sign Language to Understand Intercellular Communication9
An Inflection Point in Cancer Protein Biomarkers: What was and What's Next9
Facioscapulohumeral Muscular Dystrophy is Associated With Altered Myoblast Proteome Dynamics9
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Cover8
Proteomics, Transcriptomics, and Phosphoproteomics Reveal the Mechanism of Talaroconvolutin-A Suppressing Bladder Cancer via Blocking Cell Cycle and Triggering Ferroptosis8
Exploring the Early Molecular Pathogenesis of Osteoarthritis Using Differential Network Analysis of Human Synovial Fluid8
LC-SRM Combined With Machine Learning Enables Fast Identification and Quantification of Bacterial Pathogens in Urinary Tract Infections8
Red Blood Cells Protein Profile Is Modified in Breast Cancer Patients8
DIA-Based Phosphoproteomics Identifies Early Phosphorylation Events in Response to EGTA and Mannitol in Arabidopsis8
Profiling Proteins and Phosphorylation Sites During T Cell Activation Using an Integrated Thermal Shift Assay8
Differential Analysis of Cereblon Neosubstrates in Rabbit Embryos Using Targeted Proteomics8
Rescoring Peptide Spectrum Matches: Boosting Proteomics Performance by Integrating Peptide Property Predictors Into Peptide Identification8
Dichotomous Responses to Chronic Fetal Hypoxia Lead to a Predetermined Aging Phenotype8
Single Cell Proteomics Reveals Specific Cellular Subtypes in Cardiomyocytes Derived from Human iPSCs and Adult Hearts8
The Plastidial Protein Acetyltransferase GNAT1 Forms a Complex With GNAT2, yet Their Interaction Is Dispensable for State Transitions8
Serum Proteomics Identifies Biomarkers Associated With the Pathogenesis of Idiopathic Pulmonary Fibrosis8
High-throughput and high-sensitivity biomarker monitoring in body fluid by FAIMS-enhanced fast LC SureQuant™ IS targeted quantitation8
Ion Mobility–Based Enrichment-Free N-Terminomics Analysis Reveals Novel Legumain Substrates in Murine Spleen8
Interval-Based Secretomics Unravels Acute-Phase Response in Hepatocyte Model Systems8
An Introduction to Analytical Challenges, Approaches, and Applications in Mass Spectrometry–Based Secretomics8
Cover8
Mass Spectrometry–Based Proteomics Analysis of Human Substantia Nigra From Parkinson's Disease Patients Identifies Multiple Pathways Potentially Involved in the Disease8
Detection of Pancreatic Ductal Adenocarcinoma-Associated Proteins in Serum8
Acquisition and Analysis of DIA-Based Proteomic Data: A Comprehensive Survey in 20238
Multi–Cell Line Analysis of Lysosomal Proteomes Reveals Unique Features and Novel Lysosomal Proteins8
Cerebrospinal Fluid Protein Markers Indicate Neuro-Damage in SARS-CoV-2-Infected Nonhuman Primates7
Epitope Mapping of Human Polyclonal Antibodies to the fHbp Antigen of a Neisseria Meningitidis Vaccine by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS)7
MCP’s New Editorial Posture Moving Forward7
The Acyl-Proteome of Syntrophus aciditrophicus Reveals Metabolic Relationships in Benzoate Degradation7
Early Proteomic Characteristics and Changes in the Optic Nerve Head, Optic Nerve, and Retina in a Rat Model of Ocular Hypertension7
Identification and Analysis of Six Phosphorylation Sites Within the Xenopus laevis Linker Histone H1.0 C-Terminal Domain Indicate Distinct Effects on Nucleosome Structure7
Universal Pretreatment Development for Low-input Proteomics Using Lauryl Maltose Neopentyl Glycol7
Quantitative Proteomic Analysis Reveals apoE4-Dependent Phosphorylation of the Actin-Regulating Protein VASP7
Global Phosphoproteomics Unveils Kinase-Regulated Networks in Systemic Lupus Erythematosus7
Characterization of p38α Signaling Networks in Cancer Cells Using Quantitative Proteomics and Phosphoproteomics7
A Massive Proteogenomic Screen Identifies Thousands of Novel Peptides From the Human “Dark” Proteome7
Into the Dark Serum Proteome: Personalized Features of IgG1 and IgA1 Repertoires in Severe COVID-19 Patients7
A Novel Spectral Annotation Strategy Streamlines Reporting of Mono-ADP-ribosylated Peptides Derived from Mouse Liver and Spleen in Response to IFN-γ7
Proteomic Dynamics of Breast Cancer Cell Lines Identifies Potential Therapeutic Protein Targets7
Cover7
Enhanced Proteomic Coverage in Tissue Microenvironment by Immune Cell Subtype Library-Assisted DIA-MS7
Spatial Proteomics Reveals Differences in the Cellular Architecture of Antibody-Producing CHO and Plasma Cell–Derived Cells7
Deep Learning Prediction Boosts Phosphoproteomics-Based Discoveries Through Improved Phosphopeptide Identification7
Widespread Arginine Phosphorylation in Staphylococcus aureus7
Integrative Proteomics and N-Glycoproteomics Analyses of Rheumatoid Arthritis Synovium Reveal Immune-Associated Glycopeptides7
The Proteome and Phosphoproteome Uncovers Candidate Proteins Associated With Vacuolar Phosphate Signal Multipled by Vacuolar Phosphate Transporter 1 (VPT1) in Arabidopsis7
Comparative Proteomic Analysis Identifies Key Metabolic Regulators of Gemcitabine Resistance in Pancreatic Cancer7
The in vivo Interaction Landscape of Histones H3.1 and H3.37
The Second Asia-Oceania Human Proteome Organization (AOHUPO) Online Education Series on the Renaissance of Clinical Proteomics: Biomarkers, Imaging and Therapeutics7
From AI-driven synthetic biology to prediction of molecular phenotypes6
Histone Chaperone Deficiency in Arabidopsis Plants Triggers Adaptive Epigenetic Changes in Histone Variants and Modifications6
Filter-aided extracellular vesicle enrichment (FAEVEr) for proteomics6
Improved Mass Spectrometry–Based Methods Reveal Abundant Propionylation and Tissue-Specific Histone Propionylation Profiles6
Integrative Structural Biology to Understand Biological Complexity6
An AI-driven leap forward in peptide identification through deconvolution of chimeric spectra6
Validation of Predicted Neoantigens in Patient Derived Material by Targeted Mass Spectrometry6
Activity-based proteomic profiling reveals reduction of lipid hydrolase activity levels in non-small cell lung cancer tumors6
In-Depth Mass Spectrometry Analysis Reveals the Plasma Proteomic and N-Glycoproteomic Impact of an Amish-Enriched Cardioprotective Variant in B4GALT16
Developing Cross-linking Mass Spectrometry to Define Protein Interaction Landscapes6
Assessing Target Specificity of the Small Molecule Inhibitor MARIMASTAT to Snake Venom Toxins: A Novel Application of Thermal Proteome Profiling6
WITHDRAWN6
High-throughput subcellular proteomics reveals phospho-signaling dynamics6
Direct DIA database search with PEAKS Online XPro increases HLA-I peptide identification and bypasses the requirement for large spectral libraries6
Post-translational Modifications and Their Effects on the Conformation and Function of Hsp90 in Embryonic Stem Cells6
The rise of molecular glues and bifunctional compounds6
Limited Evidence for Protein Products of Noncoding Transcripts in the HEK293T Cellular Cytosol6
Identifying Patients With Rapid Progression From Hormone-Sensitive to Castration-Resistant Prostate Cancer: A Retrospective Study6
Larval Exposure to Parasitic Varroa destructor Mites Triggers Specific Immune Responses in Different Honey Bee Castes and Species6
Proteome, Lysine Acetylome, and Succinylome Identify Posttranslational Modification of STAT1 as a Novel Drug Target in Silicosis6
Identification of novel viral class I-restricted peptides in Merkel cell carcinoma6
Toward Comprehensive, Single-molecule Proteomics: Protein Identification by Shortepitope Mapping6
WITHDRAWN6
WITHDRAWN6
Functional Diversity and Evolution of the Drosophila Sperm Proteome5
Higher-Order Structural Organization of the Mitochondrial Proteome Charted by In Situ Cross-Linking Mass Spectrometry5
Cover5
Dynamic Proteomic Changes in Tumor and Immune Organs Reveal Systemic Immune Response to Tumor Development5
WITHDRAWN5
Proteome Dynamics in iPSC-Derived Human Dopaminergic Neurons5
Proteogenomic analyses of CRISPR inhibited expression of a panel genes associated with Alzheimer's disease and related dementias in iPSC-derived neurons using a fully automated workflow5
A Proteomic Approach Identifies Isoform-Specific and Nucleotide-Dependent RAS Interactions5
In Situ Cell-Surface Proteomics: Method Development and Applications in Neurobiology5
Data-Independent Acquisition: A Milestone and Prospect in Clinical Mass Spectrometry–Based Proteomics5
Direct determination of oligomeric organization of integral membrane proteins and lipids from intact customizable bilayer5
Harmonizing Labeling and Analytical Strategies to Obtain Protein Turnover Rates in Intact Adult Animals5
A BioID-derived proximity interactome for Protein Phosphatase PP2A5
Profiling the cellular signalling state by targeted phoshoproteomics5
Proteome Remodeling of the Eye Lens at 50 Years Identified With Data-Independent Acquisition5
Replisome Proximal Protein Associations and Dynamic Proteomic Changes at Stalled Replication Forks5
WITHDRAWN5
Phosphoproteome Profiling of the Receptor Tyrosine Kinase MuSK Identifies Tyrosine Phosphorylation of Rab GTPases5
Discovery of shared cancer neoantigen epitopes through mass spectrometry analysis of engineered monoallelic cell lines5
The Lysine Acetylation Modification in the Porin Aha1 of Aeromonas hydrophila Regulates the Uptake of Multidrug Antibiotics5
Proteomics-Derived Biomarker Panel Facilitates Distinguishing Primary Lung Adenocarcinomas With Intestinal or Mucinous Differentiation From Lung Metastatic Colorectal Cancer5
The Cancer Cell Mapping Initiative5
Editorial Board5
Fast and Accurate Disulfide Bridge Detection5
A Carrier-Based Quantitative Proteomics Method Applied to Biomarker Discovery in Pericardial Fluid5
PRM-LIVE Accelerates Target Class-based Selectivity Profiling of Small Molecule Inhibitors5
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