OOIR: Observatory of International Research

Papers

(The TQCC of Epilepsy Currents is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Making Up Missed Anti-Seizure Medication Doses: Double or Nothing?	37
Registry-Based Phenotyping to Improve the Diagnosis of Autoimmune Encephalitis	31
SUDEP: A Local Low Pressure [pO₂] System Makes It Hard to Breathe	28
Unblock the Block! Preventing Inhibitory Failure to Maintain Inhibitory Restraint	23
Artificial Intelligence Applications in the Imaging of Epilepsy and Its Comorbidities: Present and Future	19
Let’s Talk About Sex and Juvenile Myoclonic Epilepsy	17
Portrait of Epilepsy on the Canvas of Global Health	15
From Stumbling Blocks to Stepping Stones: Progress in Treating Temporal Lobe Epilepsy With Stem Cell Transplantation	15
Deep Brain, Deep Impact: Rethinking Pediatric Epilepsy Treatment With Deep Brain Stimulation of the Centromedian Nucleus	13
Psychosocial Burden and Suicidality in Epilepsy: A Public Health Concern	12
Efficient diagnosis leads to better care: streamlining epilepsy diagnosis pathways	11
Magnetic Resonance Imaging in Status Epilepticus: Useful Scrying Board or Expensive Stopwatch?	10
Some (Syn)Gaps are Worse than Others: Deciphering The Role of Syngap Isoforms in Excitatory Synaptic Function	10
Deep Thoughts—Predicting Initial Treatment Response in Newly Diagnosed Epilepsy	10
Ripples of Hyperexcitability in Epilepsy, Autism, and Inattention	9
Money Matters: Measuring the Economic Impact of Epilepsy	8
Drinking from the fountain of youth for mTOR-related epilepsy	8
Salty Battle to Sudden Death: Young vs. Old, Brain vs. Heart	6
Shifting Focus: The “Other” GABAR	6
A Human Touch: Hominid-Specific LRRC37B Regulates Axon Initial Segment Excitability	6
To Not Sleep, Perchance to Seize	5
More Than Reels: Cajal-Retzius Cells Become Active	5
Get Out the Door: Ambulatory EEG Trumps Routine EEG in the Detection of Interictal Epileptiform Abnormalities After a First Unprovoked Seizure	5
A Cry for Survival? Rhythmic and Periodic EEG Discharges as Treatment Targets Following Cardiac Arrest	5
Shifting Gears in Clinical Trials- Time to Event Analysis: Music to Some Ears	4

Quiet, Please—The Brain is Buzzing: Levetiracetam and the Paradox of (Fast) Ripples in Alzheimer's Disease	4
Surviving the Storm—Surviving Status Epilepticus	4
Gaining Awareness of Increasingly Persistent SCN1A Mutations	4
Over the Limit; Long-Term Seizure and Mortality Risk in Alcohol Withdrawal Seizures	4
Open Sesame: Door to Enriched Somatic Variants Underlying Sporadic mTLE	4
Frontal Lobe Epilepsy: Bermuda's Triangle	4
Midazolam, Ketamine, and Propofol: While We Slept, Others Worked on Anesthetizing Infusions for Refractory Status Epilepticus	4
Debunking the Myth: The Null Effect of Antiseizure Medications on the Functional Outcomes of Acute Symptomatic Seizures	3
Unlocking the Mysteries of Slumber: Unveiling the Intricate Ties Between Sleep, Epilepsy, and Cognition	3
Attentional Deficits and Absence Epilepsy: A Tale of 2 Interneuronopathies	3
New Neurons, Fewer Seizures: Environmental Enrichment Strengthens Brain Circuits	3
Double, Double Toil and Trouble: Recurrent Episodes of Status Epilepticus Are Associated With Increasingly Worse Outcomes	3
One to Rule Them All: A Unique TAU Therapy for Neurodevelopmental Encephalopathies	3
Women With Epilepsy: Causes for Concern	3
Genetic Networks of Drug Resistance in Epilepsy: Outputs of a Computational and Translational Disease Framework	3
No More Tears: Surgical Options and Outcomes in Hypothalamic Hamartomas	3
WITHDRAWN–How to Help Your Patients Enroll in the New-Onset Refractory Status Epilepticus (NORSE) and Febrile Infection-Related Epilepsy Syndrome (FIRES) Family Registry, and Other Rare Epilepsy Regis	3
Seizure Detection Devices in Children: One Step Closer	3
Light, Kindling, Action! Brain-Wide Circuit Changes After Optogenetic Hippocampal Kindling Revealed by Functional Magnetic Resonance Imaging	3
The Unconventional Effects of the Ketogenic Diet (KD) in Preclinical Epilepsy	3
Only Hit the Bad Guys: A Gene Therapy Approach to Selectively Silence Highly Active Neurons Reduces Chronic Seizures in Epileptic Mice	3
Two Halves Make a Whole SCN1A	3
Try, Try Again: Success Rates After Continued Treatment Attempts in Refractory Status Epilepticus	3
SEEG Radiofrequency Thermocoagulation and Memory: For Now, Avoid the Trap of Overpromising and Underdelivering	3
Channeling Seizure Control: Optogenetics in Human Brain Slices	3
Dissecting the Fatal Seizure: The Importance of Forebrain Neurons in SUDEP	3
Illuminating LGI1 Seizure Mechanisms Using Novel Optical Techniques	3
Mitigating Risk, Optimizing Care: Antiseizure Medications, Pregnancy, and Autism Spectrum Disorder Risk	3
Genetic Mechanisms Behind Severe Psychotic Reactions to Levetiracetam	2
Comprehensive Epilepsy Care: The Key to Cutting Costs and Seizing Better Outcomes	2
Not So Innocent Bystanders in Focal Cortical Dysplasia	2
Determining the Spread: Potential Biomarkers and Treatment for Seizure-Induced-Spreading Depolarization in a Mouse Model of Genetic Epilepsy	2
Depression and Epilepsy: The Bidirectional Relation Goes On and On…	2
Epilepsy After Traumatic Brain Injury: A Triple Threat to the Brain—Carpe Diem or Carpe Dementia?	2
ENVISIONing a critical period to preserve development: communication delays in SCN1A+ dravet syndrome	2
Inflammation Emerges as a Sensitizer of a Heat-Responsive Cation Channel	2
Diagnostic Yield and Treatment Changes After Genetic Testing of Adults With Epilepsy	2
iDISCO Inferno: Mapping Connectivity Changes Following TBI	2
Mechanisms of Neurostimulation for Epilepsy	2
Epilepsy Surgery: A Story of Diminishing Returns Over Time? Think Differently and Think Again	2
Sage Against the Machine: Promise and Challenge of Artificial Intelligence in Epilepsy	2
Cannabidiol Keeps Hippocampal Hyperactivity in Check	2
A Case of the “Spinnies”: Vestibular Epilepsy	2
Aurea Mediocritas: mTOR Abides the Golden Mean	2
Blame it on the Inputs: Overexcited Entorhinal Inputs Drive Dentate Gyrus Hyperexcitability in a Mouse Model of Dravet Syndrome	2
When Encephalitis Burns Out, Are You Left With a Spark?	2
Detection is Key: Automated Tonic Seizure Detection With a Wearable Device	2
The Interplay Between Epilepsy and Alzheimer’s Disease: A Pas De Deux	2
Epilepsy Care in the Real World of Multiple Medical Considerations	2
Running Out of Breath: The Diminishing Role of Gabapentinoids in Epilepsy	2

Harnessing Metabolomics to Advance Epilepsy Research	2
Seizures and Cardiac Dysrhythmias: And the Beat (Sometimes) Goes On	2
Decomposing SV2A Function and Dysfunction one Neuron at a Time	2
Navigating Transition to Adulthood in Epilepsy Patients: A Multidisciplinary Approach	1
Teratogenesis, Perinatal, and Neurodevelopmental Outcomes After In Utero Exposure to Antiseizure Medication	1
Diving Deep for Sleep: How pH and Blood Volume in the Lateral Hypothalamus Impact REM	1
Is MORE better? Accumulating Evidence for ANT DBS in Epilepsy	1
Does Deep Brain Stimulation Work in Lennox-Gastaut Syndrome? Well…it Depends	1
Neuromodulation for Refractory Epilepsy	1
Resting But Not Idle: Insights Into Epilepsy Network Suppression From Intracranial EEG	1
Epileptic Neurons Know JAK/STAT3	1
From the Murky Depths to the Brain: A Tale of a Glowing Protein That Became the Core of a Seizure-Suppressing Molecular Machinery	1
Pregnancy in Epilepsy: Moms Have Risks too	1
Osteoporosis: The Brittle Reality of an Epilepsy Diagnosis	1
Rebuilding the Tower of Babel: The Current Landscape and Emerging Opportunities in DEE-SWAS	1
Focal Seizures Cruise the Callosal Highway	1
Open the Window for the Cure of Dravet	1
Under New Management: Transplanted GABAergic Progenitors Control Adult Neurogenesis	1
Hippocampal Inhibitory Neuron Loss Is Epileptogenic But Not Likely a Sole Cause of Mesial Temporal Lobe Epilepsy (MTLE)	1
Watch Out for GATORs: Fasting, Seizures, and Nutrient Sensing	1
Lighting the Way to Seizure Cessation: Transcranial Optogenetic Therapies to Stop Seizures in Mouse Models	1
Is Node Disconnection the Key for Improving LITT Outcome?	1
More is Different in mTORopathies	1
Brain Energy Oscillations–A Possible Explanation for Seizure Periodicity in Epilepsy?	1
Prepregnancy Education: A Gap in Care for All	1
Dravet Syndrome as an Example of Precision Medicine in Epilepsy	1
ABCDEF…SUDEP: Action Potential Barrage in (Superior) Colliculus Causes (Spreading) Depolarization Leading to Epilepsy Fatality	1
Predicting Pediatric Genetic Epilepsy Through Electronic Medical Records: A Data-Driven Biomarker Discovery Approach	1
Furthering the Evidence of Comorbid Psychiatric Disorders in Pediatric Patients With Psychogenic Nonepileptic Seizures	1
Emergency: Lack of Seizure Rescue Preparedness	1
What You Don’t Look for, You Won’t Find: Value of EEG After Clinical Resolution of Convulsive Status Epilepticus	1
Zeroing in on Phenotypes While Also Broadening Our Understanding of KCNT1-Related Epilepsy	1
Through the Lens: Insights Into Sudden Death	1
The ACTH Quandary: Balancing Efficacy and Affordability for Infantile Spasms Treatment	1
Masterminding Hippocampal Circuits by Transplanting Human GABAergic Interneurons to Treat Temporal Lobe Epilepsy	1
Breaking the Synaptic Vesicle Cycle: Mechanistic Insights into Presynaptic Dysfunctions in Epilepsy	1
The RNS Crystal Ball Sees Seizure Improvement in Your Future With This Medication	1
Implementing Clinical Practice Guidelines: Considerations for Epileptologists	1
Connectome the Dots for Presurgical Predictions	1
One for All—Can We Have and Do We Want a First-Line Monotherapy for Epilepsy?	1
That’s a Wrap: Could Controlling Activity-Regulated Myelination Prevent Absence Seizures?	1
No Time to Die – Avoidable Death in Epilepsy	1
Molecular Layer Heterotopia: Harmless Brain Warts or Ictal Main Force?	1
Brain on Fire: How Brain Infection and Neuroinflammation Drive Worldwide Epilepsy Burden	1
Newly Identified KCNA3 Gene Variants Put the “Excite”-ment Back in Kv1.3 Channelopathy	1
Spreading Depolarization and Seizures: End of the Beginning, or Beginning of the End?	1
Revoking the Seize Order: Preventing Spontaneous Seizures With AAV in a CLN2 Mouse Model	1
Mechanisms of Subiculum Hyperexcitability in Temporal Lobe Epilepsy	1
Memories in Persons with Epilepsy: They Are More Fragile Than You Think	1
ENIGMA in ACAPULCO: Machine Learning Localization of Cerebellar Anatomy in Epilepsy	1
REVing up the Brain: A Mechanism Driving Seizure Timing	1
Et tu, CA2: CA2 Is Hyperexcitable and Controls Seizures in a Mouse Model of Temporal Lobe Epilepsy	1
Persistent Underdosing of Benzodiazepines for Status Epilepticus: The Weight Is the Hardest Part	1
Ictogenesis? That’s Random…..	1
Leigh has no Brakes: Impaired Inhibition in a Mouse Model of Leigh Syndrome Leads to Enhanced Seizure Sensitivity	1
Can a Mouse Help Us Unravel the Mysteries of CDKL5-Related Epilepsy?	1
KCN Channels “Cue” Up GABA Release from Astrocytes	1
“Fasting? Not too Fast”; a Clinical Insight into the Impact of Fasting on Seizure Control in Patients with Epilepsy	1
Solving the Molecular Basis of the Developmental and Epileptic Encephalopathies: Are We there Yet?	1
The State of Specialized Epilepsy Care in the States: Increased Access, New Tools, but the Same Dismal Underutilization of Epilepsy Surgery	1
It Takes Two to Tango: Channel Interplay Leads to Paradoxical Hyperexcitability in a Loss-of-Function Epilepsy Variant	1
AI-nalyzing Mouse Behavior to Combat Epilepsy	1
Better Together: Building Bridges for Equity in Epilepsy Care	1
The BEST Conceivable Way to Talk About Epilepsy Biomarkers	1
The Stigmatizing Impact of Perceived Epilepsy Stigma	1
An EEG in Time Saves Nine: Predicting Cognitive Decline in Epilepsy	1
Do Seizures Damage the Brain ?—Cumulative Effects of Seizures and Epilepsy: A 2025 Perspective	1