OOIR: Observatory of International Research

Papers

(The TQCC of Epilepsy Currents is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
The Role of the Persistent Sodium Current in Epilepsy	32
Perineuronal Net Dynamics in the Pathophysiology of Epilepsy	30
Integrating Network Neuroscience Into Epilepsy Care: Progress, Barriers, and Next Steps	24
Neuromodulation for Refractory Epilepsy	23
Treatment of Super-Refractory Status Epilepticus: A Review	21
Arousal and Consciousness in Focal Seizures	19
Wheels Within Wheels: Theory and Practice of Epileptic Networks	19
Untangling a Web: Basic Mechanisms of the Complex Interactions Between Sleep, Circadian Rhythms, and Epilepsy	14
Toward Understanding the Diverse Roles of Perisomatic Interneurons in Epilepsy	14
Low Intensity Focused Ultrasound for Epilepsy— A New Approach to Neuromodulation	13
Emerging Trends in Neuroimaging of Epilepsy	13
FDA Safety Warning on the Cardiac Effects of Lamotrigine: An Advisory From the Ad Hoc ILAE/AES Task Force	13
Paxlovid^TM Information From FDA and Guidance for AES Members	10
Current Review in Basic Science: Animal Models of Focal Cortical Dysplasia and Epilepsy	10
Synergistic Positive Feedback Mechanisms Underlying Seizure Initiation	10
Are Genetic Therapies for Epilepsy Ready for the Clinic?	9
Machine Learning for Precision Epilepsy Surgery	7
What Causes Seizures in Neurocysticercosis?	7
Proceedings of the Sleep and Epilepsy Workshop: Section 2 Comorbidities: Sleep Related Comorbidities of Epilepsy	7
Inflammation Unleashed in Viral-Induced Epileptogenesis	7
Seizing Control of Neuronal Activity: Chemogenetic Applications in Epilepsy	7
Dravet Syndrome as an Example of Precision Medicine in Epilepsy	7
Artificial Intelligence Applications in the Imaging of Epilepsy and Its Comorbidities: Present and Future	7
Stimulating Solutions for Intractable Epilepsy	6
Proceedings of the Sleep and Epilepsy Workshop: Section 1 Decreasing Seizures: Improving Sleep and Seizures, Themes for Future Research	5

Epilepsy-Specific Anxiety: A Potential Clue to the Seizure Onset Zone	5
TANGO With SCN1A: Can This Molecular Dance Defeat Dravet Syndrome?	5
Ganaxolone: A New Treatment for CDKL5 Deficiency Disorder	5
Proceedings of the Sleep and Epilepsy Workshop: Section 3 Mortality: Sleep, Night, and SUDEP	5
Epilepsy and Neurodegeneration: A Bidirectional Relationship	4
Forecasting Seizure Storms Using Epilepsy Wristband Sensors	4
Epilepsy and COVID 2021	4
Too Much of a Good Thing? High-Dose Folic Acid in Pregnancy and Childhood Cancer	4
The 2021 Epilepsy Research Benchmarks—Respecting Core Principles, Reflecting Evolving Community Priorities	4
The BEST Conceivable Way to Talk About Epilepsy Biomarkers	4
Rise of the Machines? Predicting Brivaracetam Response Using Machine Learning	4
Epilepsy, Cardiovascular Risks, and Dementia: A Ménage à Trois	4
Stroke and Ischemic Heart Disease With Enzyme-inducing Antiseizure Medications: Time to Change Prescribing Habits	3
Dynamic Fluorescence Imaging in Experimental Epilepsy	3
Cheers for SANTĖ: Long Term Safety and Efficacy of Anterior Nucleus of the Thalamus DBS	3
Harnessing Metabolomics to Advance Epilepsy Research	3
How to Help Your Patients Enroll in the New-Onset Refractory Status Epilepticus (NORSE) and Febrile Infection-Related Epilepsy Syndrome (FIRES) Family Registry, and Other Rare Epilepsy Registries	3
Accreditation of Epilepsy Centers	3
Closing the Diagnostic Gap in Epilepsy: Recognizing More Than Just Motor Seizures	3
A Cry for Survival? Rhythmic and Periodic EEG Discharges as Treatment Targets Following Cardiac Arrest	3
Can Treating Patients With PNES Lower the Risk of Sudden Unexpected Death?	3
Epilepsy Community at an Inflection Point: Translating Research Toward Curing the Epilepsies and Improving Patient Outcomes	3
COVID-19 Incidence and Death Rate in Epilepsy: Too Early to Tell?	3
Solving the Molecular Basis of the Developmental and Epileptic Encephalopathies: Are We there Yet?	3
The (Extracellular) Matrix Reloaded: Imaging Matrix Metalloproteinase Activity	3
TRAPing Seizures in the Striatum	3
Does SARS-CoV-2 Cause Seizures and Epilepsy in COVID-19 via Inflammation or by Direct Infection?	3
Progressive Neuronal Loss in Epilepsy – A Long-Standing Conundrum Finally Resolved?	2
Start Low and Go Slow: The General Principle of Managing Older Adults With Epilepsy Finds Robust Support From Frailty	2
Late-Onset Epilepsy: A Distinct Entity that Begins and Ends With the Associated Comorbidities	2
Depression and Epilepsy: The Bidirectional Relation Goes On and On…	2
Does Deep Brain Stimulation Work in Lennox-Gastaut Syndrome? Well…it Depends	2
Breastfeeding and the Neurologist: An Important Role for Us	2
Super K for Super-R(efractory) Status Epilepticus: Bringing Down Seizures While Keeping Up Blood Pressure With Ketamine	2
Light, Kindling, Action! Brain-Wide Circuit Changes After Optogenetic Hippocampal Kindling Revealed by Functional Magnetic Resonance Imaging	2
Hit by a Smooth CD8: T-Cell Attack on Hippocampal Neurons Triggers Limbic Encephalitis and Epilepsy	2
Epilepsy and Anti-Seizure Medications: Secret Agents for Endocrine Disruption	2
Money Matters: Measuring the Economic Impact of Epilepsy	2
Pregnancy Effects on Seizure Frequency: To Seize or Not to Seize	2
The Molecular Dichotomy Between Epileptic and Functional Seizures	2
Neuronal Physiology of Generalized Seizures: The 4 Horsemen of Absence Epilepsy	2
Modifiable Risk Factors of Dementia in Older Adults With Epilepsy: An Opportunity to Flatten the Curve?	2
Using the TTX Model to Better Understand the Pathophysiology of a DREADDed Epilepsy—Infantile (Epileptic) Spasms	2
SANAD II: Dear Levetiracetam, the Honeymoon Is Over	2
Epilepsy Research Now in 3D: Harnessing the Power of Brain Organoids in Epilepsy	2
Neuro2D Lies at the Nexus of Autism, Epilepsy, and Intellectual Disabilities	2
Treating Seizures With Low-Frequency Electrical Stimulation	2
Don’t Get BUM’d Out: Bumetanide May yet Prove Beneficial for Neonatal Seizures	2
Continuous EEG in ICU: Not a Luxury After All	2
Nomograms Should Not Be Used by General Neurologists When Considering Referral for Epilepsy Surgery	2

Epilepsy as a Disease of White Matter	2
Will There Be a Seizure? Predicting Seizures in Children (and Adults) with Familial Cerebral Cavernous Malformations	2
Epilepsy Surgery: A Story of Diminishing Returns Over Time? Think Differently and Think Again	2
Guardians of the Frequency: Neuronal Regulation by Microglia	2
Sometimes, More Is More: Antiseizure Medication polytherapy Is Associated With Decreased SUDEP Risk	2
Exploring CITEs of Inflammation in the Human Epilepsy Brain	2
Can EEG Abnormalities be a Biomarker of Epileptogenesis?	2
Connectivity and Excitability Shape Seizure Circuits	2
Entering the Era of Personalized Medicine in Epilepsy Through Neuroimaging Machine Learning	2
The Search for Autoimmune-Associated Epilepsy Continues—Are We Getting Closer to Our Target?	2
Flattening the Curve: Slowing Age-Accelerated Brain Atrophy With Epilepsy Surgery	2
Stop Being So Negative: Favorable Outcome and Response to Immune Therapies in Antibody-Negative Probable Autoimmune Encephalitis	1
The Deep Breath Before the Plunge: Ictal Apnea and the Amygdala	1
Quelling the Area Tempesta: Removal of the Piriform Cortex Improves the Outcomes of Surgery for Temporal Lobe Epilepsy	1
The State of Specialized Epilepsy Care in the States: Increased Access, New Tools, but the Same Dismal Underutilization of Epilepsy Surgery	1
When Apnea Turns Terminal: When, How, Why?	1
Same Channel, Different Tune	1
Caution: Benzodiazepines in Pregnancy and Risk of Adverse Perinatal Outcomes	1
Stop the Lights—Turning Off the Electricity in Tuberous Sclerosis	1
Breaking the Seizure Randomness Myth: Evidence for a Recurring Ebb and Flow of Seizure Risk on the Continuum of Time	1
Dollars and Sense: Cost-Effectiveness of Epilepsy Surgery	1
Optokindling, GABA Dwindling	1
Lesional Epilepsy in Children: Removing Doubt to Cut It Out	1
To Not Sleep, Perchance to Seize	1
Risky Business: Traumatic Brain Injury and Epilepsy	1
More Than Reels: Cajal-Retzius Cells Become Active	1
Exploring Dendritic and Spine Structural Profiles in Epilepsy: Insights From Human Studies and Experimental Animal Models	1
Treating Post-Traumatic Seizures to Limit Tau Accumulation in Larval Zebrafish	1
Not a Slam-Dunk: Assessing the Role of EEG/fMRI in the Presurgical Evaluation	1
Mechanisms of Neurostimulation for Epilepsy	1
Adolescence and Epilepsy: The Perfect Storm for Suicidal Behavior	1
RNS—It Never Gets Old	1
Parental Counseling About Sudden Unexpected Death in Epilepsy: Why, When, Where, What, Who, and How?	1
Machine Learning to Address the Enigma of Temporal Lobe Epilepsy Lateralization	1
Brain on Fire: How Brain Infection and Neuroinflammation Drive Worldwide Epilepsy Burden	1
Mechanisms of Subiculum Hyperexcitability in Temporal Lobe Epilepsy	1
Pump-Opathies: Mutations in Na⁺–K⁺-ATPase Genes Produce Severe Developmental Epileptic Encephalopathies	1
That’s a Wrap: Could Controlling Activity-Regulated Myelination Prevent Absence Seizures?	1
Benzodiazepines for Out-of-Hospital Status Epilepticus: Do or Do Not! There Is No Try!	1
The Temporal Lobe Club: Newer Approaches to Treat Temporal Lobe Epilepsy	1
Persistent Underdosing of Benzodiazepines for Status Epilepticus: The Weight Is the Hardest Part	1
Seizing Off This Mortal Coil: A Matter of Epilepsy and Death	1
You Snooze You Seize: GABAergic Potentiation of Genetic Generalized Seizures During NREM	1
Don’t Hesitate to Vaccinate—The Safety of Covid-19 Vaccination and Epilepsy	1
Neurons Are GIRKed in GNB1 Encephalopathy: Unraveling Pathogenic Mechanisms in a Complex Neurodevelopmental Disorder	1
Should We Be Going With Our Patient’s Gut (Bacteria)? The Intestinal Microbiota and Epilepsy Treatments	1
Highlights From AES2020, a Virtual American Epilepsy Society Experience	1
Slow Down and Seize: Seizures Triggered by Slow Wave Oscillations in a GABAergic Model of Dravet Syndrome	1
Neuronal Superhubs: Elite Networks that Rule Synchrony	1
Genetic Testing in Epilepsy: Improving Outcomes and Informing Gaps in Research	1
Transforming Glia to Neurons Effectively Treats Temporal Lobe Seizures	1
Is STN Neuromodulation of Focal Motor Seizures Ready for Prime Time?	1
Keeping up with KCNQ2: A New Model of Epileptic Encephalopathy	1
Anti-Epileptogenesis: Some Roads Lead to Losartan	1
Targeting Epileptogenesis: A Conceptual Black Hole or Light at the End of the Tunnel?	1
Suicidality: Once Again, Don’t Blame the Drug Class	1
Is MORE better? Accumulating Evidence for ANT DBS in Epilepsy	1
Tuning the Wave: Controlling Spreading Depolarization with Activation/Inactivation of Kv7.2	1
Cutting-Edge Classification of Focal Cortical Dysplasia for Epilepsy Surgery	1
Open the Window for the Cure of Dravet	1
No Time to Die – Avoidable Death in Epilepsy	1
Relationship Status Update on Astrocytic VEGFR-3 and mTOR Signaling: It’s Complicated	1
Neonatal Seizures: Providing Care With Evidence, Not Just Experience	1
Registry-Based Phenotyping to Improve the Diagnosis of Autoimmune Encephalitis	1
Of Blobs and Buzzes: Does SISCOM Imaging Actually Help SEEG Planning?	1
Dendritic and Spine Loss in Epilepsy: What Seizures Got to Do With It?	1
Blame it on the Inputs: Overexcited Entorhinal Inputs Drive Dentate Gyrus Hyperexcitability in a Mouse Model of Dravet Syndrome	1
Networks Inhibited and Networks Excited: Loss of Consciousness in Epilepsy	1
Who Dunnit? Angiotensin, Inflammation, or Complement: Unresolved	1
Reconsidering Network Mechanisms in Absence Seizures: Unhitching the Wave Cart From the Spike Horse	1
Deep Thoughts—Predicting Initial Treatment Response in Newly Diagnosed Epilepsy	1
From the Subiculum to the Anterior Nuclei of the Thalamus: The Key to Hippocampal Seizure Generalization?	1
Microglial Cells in Epilepsy: Not That Bad After All?	1
Time Is Brain: The Importance of an Accurate SCN1A Prediction Score in the Era of Precision Medicine	1
Magnetic Resonance Imaging in Status Epilepticus: Useful Scrying Board or Expensive Stopwatch?	1
Sage Against the Machine: Promise and Challenge of Artificial Intelligence in Epilepsy	1