OOIR: Observatory of International Research

Papers

(The TQCC of Epilepsy Currents is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Making Up Missed Anti-Seizure Medication Doses: Double or Nothing?	35
Registry-Based Phenotyping to Improve the Diagnosis of Autoimmune Encephalitis	33
SUDEP: A Local Low Pressure [pO₂] System Makes It Hard to Breathe	30
Unblock the Block! Preventing Inhibitory Failure to Maintain Inhibitory Restraint	27
Let’s Talk About Sex and Juvenile Myoclonic Epilepsy	22
Artificial Intelligence Applications in the Imaging of Epilepsy and Its Comorbidities: Present and Future	20
From Stumbling Blocks to Stepping Stones: Progress in Treating Temporal Lobe Epilepsy With Stem Cell Transplantation	15
Epilepsy Community at an Inflection Point: Translating Research Toward Curing the Epilepsies and Improving Patient Outcomes	15
Psychosocial Burden and Suicidality in Epilepsy: A Public Health Concern	14
Some (Syn)Gaps are Worse than Others: Deciphering The Role of Syngap Isoforms in Excitatory Synaptic Function	12
A Human Touch: Hominid-Specific LRRC37B Regulates Axon Initial Segment Excitability	11
Magnetic Resonance Imaging in Status Epilepticus: Useful Scrying Board or Expensive Stopwatch?	11
Efficient diagnosis leads to better care: streamlining epilepsy diagnosis pathways	10
Deep Thoughts—Predicting Initial Treatment Response in Newly Diagnosed Epilepsy	10
Ripples of Hyperexcitability in Epilepsy, Autism, and Inattention	9
Drinking from the fountain of youth for mTOR-related epilepsy	8
Money Matters: Measuring the Economic Impact of Epilepsy	7
Shifting Focus: The “Other” GABAR	7
Get Out the Door: Ambulatory EEG Trumps Routine EEG in the Detection of Interictal Epileptiform Abnormalities After a First Unprovoked Seizure	6
Open Sesame: Door to Enriched Somatic Variants Underlying Sporadic mTLE	5
A Cry for Survival? Rhythmic and Periodic EEG Discharges as Treatment Targets Following Cardiac Arrest	5
To Not Sleep, Perchance to Seize	5
More Than Reels: Cajal-Retzius Cells Become Active	5
Shifting Gears in Clinical Trials- Time to Event Analysis: Music to Some Ears	4
Frontal Lobe Epilepsy: Bermuda's Triangle	4

Disentangling the Gordian Knot of Drug-Resistant Epilepsy	4
Surviving the Storm—Surviving Status Epilepticus	4
Illuminating LGI1 Seizure Mechanisms Using Novel Optical Techniques	3
No More Tears: Surgical Options and Outcomes in Hypothalamic Hamartomas	3
Midazolam, Ketamine, and Propofol: While We Slept, Others Worked on Anesthetizing Infusions for Refractory Status Epilepticus	3
Unlocking the Mysteries of Slumber: Unveiling the Intricate Ties Between Sleep, Epilepsy, and Cognition	3
Genetic Networks of Drug Resistance in Epilepsy: Outputs of a Computational and Translational Disease Framework	3
Try, Try Again: Success Rates After Continued Treatment Attempts in Refractory Status Epilepticus	3
Over the Limit; Long-Term Seizure and Mortality Risk in Alcohol Withdrawal Seizures	3
Attentional Deficits and Absence Epilepsy: A Tale of 2 Interneuronopathies	3
One to Rule Them All: A Unique TAU Therapy for Neurodevelopmental Encephalopathies	3
Mitigating Risk, Optimizing Care: Antiseizure Medications, Pregnancy, and Autism Spectrum Disorder Risk	3
Debunking the Myth: The Null Effect of Antiseizure Medications on the Functional Outcomes of Acute Symptomatic Seizures	3
Light, Kindling, Action! Brain-Wide Circuit Changes After Optogenetic Hippocampal Kindling Revealed by Functional Magnetic Resonance Imaging	3
Like Mother, Like Child. Keeping Control of Seizures During Pregnancy	3
Gaining Awareness of Increasingly Persistent SCN1A Mutations	3
Double, Double Toil and Trouble: Recurrent Episodes of Status Epilepticus Are Associated With Increasingly Worse Outcomes	3
The Unconventional Effects of the Ketogenic Diet (KD) in Preclinical Epilepsy	3
Channeling Seizure Control: Optogenetics in Human Brain Slices	3
Only Hit the Bad Guys: A Gene Therapy Approach to Selectively Silence Highly Active Neurons Reduces Chronic Seizures in Epileptic Mice	3
Women With Epilepsy: Causes for Concern	3
Salty Battle to Sudden Death: Young vs. Old, Brain vs. Heart	3
The Interplay Between Epilepsy and Alzheimer’s Disease: A Pas De Deux	2
Mechanisms of Neurostimulation for Epilepsy	2
Not So Innocent Bystanders in Focal Cortical Dysplasia	2
When Encephalitis Burns Out, Are You Left With a Spark?	2
WITHDRAWN–How to Help Your Patients Enroll in the New-Onset Refractory Status Epilepticus (NORSE) and Febrile Infection-Related Epilepsy Syndrome (FIRES) Family Registry, and Other Rare Epilepsy Regis	2
Cannabidiol Keeps Hippocampal Hyperactivity in Check	2
Epilepsy After Traumatic Brain Injury: A Triple Threat to the Brain—Carpe Diem or Carpe Dementia?	2
Depression and Epilepsy: The Bidirectional Relation Goes On and On…	2
Inflammation Emerges as a Sensitizer of a Heat-Responsive Cation Channel	2
Genetic Mechanisms Behind Severe Psychotic Reactions to Levetiracetam	2
Detection is Key: Automated Tonic Seizure Detection With a Wearable Device	2
Seizure Detection Devices in Children: One Step Closer	2
Sage Against the Machine: Promise and Challenge of Artificial Intelligence in Epilepsy	2
Blame it on the Inputs: Overexcited Entorhinal Inputs Drive Dentate Gyrus Hyperexcitability in a Mouse Model of Dravet Syndrome	2
Implementing Clinical Practice Guidelines: Considerations for Epileptologists	2
Seizures and Cardiac Dysrhythmias: And the Beat (Sometimes) Goes On	2
Determining the Spread: Potential Biomarkers and Treatment for Seizure-Induced-Spreading Depolarization in a Mouse Model of Genetic Epilepsy	2
iDISCO Inferno: Mapping Connectivity Changes Following TBI	2
Comprehensive Epilepsy Care: The Key to Cutting Costs and Seizing Better Outcomes	2
SEEG Radiofrequency Thermocoagulation and Memory: For Now, Avoid the Trap of Overpromising and Underdelivering	2
Diagnostic Yield and Treatment Changes After Genetic Testing of Adults With Epilepsy	2
Epilepsy Surgery: A Story of Diminishing Returns Over Time? Think Differently and Think Again	2
Harnessing Metabolomics to Advance Epilepsy Research	2
ENVISIONing a critical period to preserve development: communication delays in SCN1A+ dravet syndrome	2
Running Out of Breath: The Diminishing Role of Gabapentinoids in Epilepsy	2
Brain on Fire: How Brain Infection and Neuroinflammation Drive Worldwide Epilepsy Burden	1
Progressive Neuronal Loss in Epilepsy – A Long-Standing Conundrum Finally Resolved?	1
Masterminding Hippocampal Circuits by Transplanting Human GABAergic Interneurons to Treat Temporal Lobe Epilepsy	1

Navigating Transition to Adulthood in Epilepsy Patients: A Multidisciplinary Approach	1
The 2021 Epilepsy Research Benchmarks—Respecting Core Principles, Reflecting Evolving Community Priorities	1
ABCDEF…SUDEP: Action Potential Barrage in (Superior) Colliculus Causes (Spreading) Depolarization Leading to Epilepsy Fatality	1
Leigh has no Brakes: Impaired Inhibition in a Mouse Model of Leigh Syndrome Leads to Enhanced Seizure Sensitivity	1
Diving Deep for Sleep: How pH and Blood Volume in the Lateral Hypothalamus Impact REM	1
Breaking the Synaptic Vesicle Cycle: Mechanistic Insights into Presynaptic Dysfunctions in Epilepsy	1
Family Ties: Reproductive Decision Making Among Members of Multiplex Epilepsy Families	1
That’s a Wrap: Could Controlling Activity-Regulated Myelination Prevent Absence Seizures?	1
Is Node Disconnection the Key for Improving LITT Outcome?	1
Connectome the Dots for Presurgical Predictions	1
Open the Window for the Cure of Dravet	1
Spreading Depolarization and Seizures: End of the Beginning, or Beginning of the End?	1
Lighting the Way to Seizure Cessation: Transcranial Optogenetic Therapies to Stop Seizures in Mouse Models	1
Under New Management: Transplanted GABAergic Progenitors Control Adult Neurogenesis	1
Teratogenesis, Perinatal, and Neurodevelopmental Outcomes After In Utero Exposure to Antiseizure Medication	1
ENIGMA in ACAPULCO: Machine Learning Localization of Cerebellar Anatomy in Epilepsy	1
Persistent Underdosing of Benzodiazepines for Status Epilepticus: The Weight Is the Hardest Part	1
Is MORE better? Accumulating Evidence for ANT DBS in Epilepsy	1
Focal Seizures Cruise the Callosal Highway	1
Do Seizures Damage the Brain ?—Cumulative Effects of Seizures and Epilepsy: A 2025 Perspective	1
Revoking the Seize Order: Preventing Spontaneous Seizures With AAV in a CLN2 Mouse Model	1
The RNS Crystal Ball Sees Seizure Improvement in Your Future With This Medication	1
Zeroing in on Phenotypes While Also Broadening Our Understanding of KCNT1-Related Epilepsy	1
Solving the Molecular Basis of the Developmental and Epileptic Encephalopathies: Are We there Yet?	1
AI-nalyzing Mouse Behavior to Combat Epilepsy	1
Can a Mouse Help Us Unravel the Mysteries of CDKL5-Related Epilepsy?	1
The State of Specialized Epilepsy Care in the States: Increased Access, New Tools, but the Same Dismal Underutilization of Epilepsy Surgery	1
The BEST Conceivable Way to Talk About Epilepsy Biomarkers	1
Osteoporosis: The Brittle Reality of an Epilepsy Diagnosis	1
Molecular Layer Heterotopia: Harmless Brain Warts or Ictal Main Force?	1
The Stigmatizing Impact of Perceived Epilepsy Stigma	1
Ictogenesis? That’s Random…..	1
It Takes Two to Tango: Channel Interplay Leads to Paradoxical Hyperexcitability in a Loss-of-Function Epilepsy Variant	1
Stop the Lights—Turning Off the Electricity in Tuberous Sclerosis	1
Pregnancy in Epilepsy: Moms Have Risks too	1
Newly Identified KCNA3 Gene Variants Put the “Excite”-ment Back in Kv1.3 Channelopathy	1
KCN Channels “Cue” Up GABA Release from Astrocytes	1
Predicting Pediatric Genetic Epilepsy Through Electronic Medical Records: A Data-Driven Biomarker Discovery Approach	1
From the Murky Depths to the Brain: A Tale of a Glowing Protein That Became the Core of a Seizure-Suppressing Molecular Machinery	1
Et tu, CA2: CA2 Is Hyperexcitable and Controls Seizures in a Mouse Model of Temporal Lobe Epilepsy	1
Through the Lens: Insights Into Sudden Death	1
No Time to Die – Avoidable Death in Epilepsy	1
Epileptic Neurons Know JAK/STAT3	1
To Stop the Seizure, You Must Become the Seizure: Closed-Loop Stimulation Phase Locked to Seizure Waves Disrupts Kindled Seizures While Open-Loop Stimulation Fails	1
Neuromodulation for Refractory Epilepsy	1
You Snooze You Seize: GABAergic Potentiation of Genetic Generalized Seizures During NREM	1
The ACTH Quandary: Balancing Efficacy and Affordability for Infantile Spasms Treatment	1
One for All—Can We Have and Do We Want a First-Line Monotherapy for Epilepsy?	1
Watch Out for GATORs: Fasting, Seizures, and Nutrient Sensing	1
Hippocampal Inhibitory Neuron Loss Is Epileptogenic But Not Likely a Sole Cause of Mesial Temporal Lobe Epilepsy (MTLE)	1
The Decline of Screening: Psychiatry is Just Not that Simple	1
A “Sodium Drug” for Generalized Epilepsy? A Mystery That Still Needs to be Solved	1
Hit by a Smooth CD8: T-Cell Attack on Hippocampal Neurons Triggers Limbic Encephalitis and Epilepsy	1
More is Different in mTORopathies	1
Brain Energy Oscillations–A Possible Explanation for Seizure Periodicity in Epilepsy?	1
Dravet Syndrome as an Example of Precision Medicine in Epilepsy	1
Mechanisms of Subiculum Hyperexcitability in Temporal Lobe Epilepsy	1
Don’t Get BUM’d Out: Bumetanide May yet Prove Beneficial for Neonatal Seizures	1