Epilepsy Currents

Article	Citations
Intracranial EEG in the 21st Century	65
Treatment of Refractory Convulsive Status Epilepticus: A Comprehensive Review by the American Epilepsy Society Treatments Committee	59
A 2020 View on the Genetics of Developmental and Epileptic Encephalopathies	40
The Impact of COVID-19 on Epilepsy Care: A Survey of the American Epilepsy Society Membership	36
HFO to Measure Seizure Propensity and Improve Prognostication in Patients With Epilepsy	28
Perineuronal Net Dynamics in the Pathophysiology of Epilepsy	23
The Role of the Persistent Sodium Current in Epilepsy	22
Network Dysfunction in Comorbid Psychiatric Illnesses and Epilepsy	21
Brain Inflammation and Seizures: Evolving Concepts and New Findings in the Last 2 Decades	20
Neuromodulation for Refractory Epilepsy	19
Integrating Network Neuroscience Into Epilepsy Care: Progress, Barriers, and Next Steps	19
Human Brain Organoid Models of Developmental Epilepsies	17
Treatment of Super-Refractory Status Epilepticus: A Review	17
Wheels Within Wheels: Theory and Practice of Epileptic Networks	17
Arousal and Consciousness in Focal Seizures	16
COVID-19 in Patients With Seizures and Epilepsy: Interpretation of Relevant Knowledge of Presenting Signs and Symptoms	15
mTORopathies: A Road Well-Traveled	14
Emerging Trends in Neuroimaging of Epilepsy	13
FDA Safety Warning on the Cardiac Effects of Lamotrigine: An Advisory From the Ad Hoc ILAE/AES Task Force	11
Low Intensity Focused Ultrasound for Epilepsy— A New Approach to Neuromodulation	10
Genetic Contributions to Acquired Epilepsies	10
Night Watch on the Titanic: Detecting Early Signs of Epileptogenesis in Alzheimer Disease	10
Toward Understanding the Diverse Roles of Perisomatic Interneurons in Epilepsy	9
PaxlovidTM Information From FDA and Guidance for AES Members	9
Untangling a Web: Basic Mechanisms of the Complex Interactions Between Sleep, Circadian Rhythms, and Epilepsy	8

Teratogenicity and Antiseizure Medications	7
Proceedings of the Sleep and Epilepsy Workshop: Section 2 Comorbidities: Sleep Related Comorbidities of Epilepsy	7
Is fMRI Ready to Replace IAP? Wait, Wait,…We Are Not There Yet!	7
Stimulating Solutions for Intractable Epilepsy	6
Loss of GABAergic Interneurons in Seizure-Induced Epileptogenesis—Two Decades Later and in a More Complex World	6
Current Review in Basic Science: Animal Models of Focal Cortical Dysplasia and Epilepsy	6
When the Brakes Fail: Basal Ganglia and Seizure Generalization	6
Artificial Intelligence Applications in the Imaging of Epilepsy and Its Comorbidities: Present and Future	5
Dravet Syndrome as an Example of Precision Medicine in Epilepsy	5
Surface or Depth: A Paradigm Shift in Invasive Epilepsy Monitoring	5
Proceedings of the Sleep and Epilepsy Workshop: Section 3 Mortality: Sleep, Night, and SUDEP	5
Machine Learning for Precision Epilepsy Surgery	4
The 2021 Epilepsy Research Benchmarks—Respecting Core Principles, Reflecting Evolving Community Priorities	4
Rodent EEG: Expanding the Spectrum of Analysis	4
Promoting CRISPRa for Targeted Treatment of Epilepsy	4
Synergistic Positive Feedback Mechanisms Underlying Seizure Initiation	4
Rise of the Machines? Predicting Brivaracetam Response Using Machine Learning	4
Responsive Neurostimulation in Epilepsy: Wall to Block Seizures or Bridge to Resection?	4
Are Genetic Therapies for Epilepsy Ready for the Clinic?	4
How Deep Learning Solved My Seizure Detection Problems	4
TANGO With SCN1A: Can This Molecular Dance Defeat Dravet Syndrome?	4
Forecasting Seizure Storms Using Epilepsy Wristband Sensors	4
Seizing Control of Neuronal Activity: Chemogenetic Applications in Epilepsy	4
Gene Therapy in Models of Severe Epilepsy due to Sodium Channelopathy	4
Closing the Diagnostic Gap in Epilepsy: Recognizing More Than Just Motor Seizures	3
Solving the Molecular Basis of the Developmental and Epileptic Encephalopathies: Are We there Yet?	3
Epilepsy and COVID 2021	3
Epilepsy Genetics: What Once Was Rare, Is Now Common	3
The Molecular Dichotomy Between Epileptic and Functional Seizures	3
Can Treating Patients With PNES Lower the Risk of Sudden Unexpected Death?	3
Proceedings of the Sleep and Epilepsy Workshop: Section 1 Decreasing Seizures: Improving Sleep and Seizures, Themes for Future Research	3
Further Evidence Breastfeeding by Women With Epilepsy Is Safe: Are Mothers Getting the Message?	3
COVID-19 Incidence and Death Rate in Epilepsy: Too Early to Tell?	3
Epilepsy With Myoclonic Atonic Seizures: Why Is the Yield of Genetic Testing for a “Presumed Genetic” Epilepsy Low?	3
Perspective: Is Cortical Hyperexcitability the Only Path to Generalized Absence Epilepsy?	3
The (Extracellular) Matrix Reloaded: Imaging Matrix Metalloproteinase Activity	3
SUDEP: Advances and Challenges	3
Accreditation of Epilepsy Centers	3
A Tisket a Tasket: Chandelier ≠ Basket (Cell Bouton Density in Sclerotic DG)	3
Epilepsy and Neurodegeneration: A Bidirectional Relationship	3
Inflammation Unleashed in Viral-Induced Epileptogenesis	3
COVID-19 EEG Studies: The Other Coronavirus Spikes We Need to Worry About	3
TRAPing Seizures in the Striatum	3
Epilepsy Community at an Inflection Point: Translating Research Toward Curing the Epilepsies and Improving Patient Outcomes	3
Stroke and Ischemic Heart Disease With Enzyme-inducing Antiseizure Medications: Time to Change Prescribing Habits	3
KCa3.1 Impairment Is Not Just a Slow Afterthought in Epilepsy	3
Ganaxolone: A New Treatment for CDKL5 Deficiency Disorder	2
Chronic DREADD Isn’t As Bad As It Sounds	2
Don’t Get BUM’d Out: Bumetanide May yet Prove Beneficial for Neonatal Seizures	2
Functional Hemispherectomy in Adults: All We Have to Sphere Is Sphere Itself	2

Too Much of a Good Thing? High-Dose Folic Acid in Pregnancy and Childhood Cancer	2
Pregnancy Effects on Seizure Frequency: To Seize or Not to Seize	2
Can EEG Abnormalities be a Biomarker of Epileptogenesis?	2
Does SARS-CoV-2 Cause Seizures and Epilepsy in COVID-19 via Inflammation or by Direct Infection?	2
Super K for Super-R(efractory) Status Epilepticus: Bringing Down Seizures While Keeping Up Blood Pressure With Ketamine	2
First Randomized Study of Epilepsy Surgery: 20 Years Later What Has Changed?	2
Treating Seizures With Low-Frequency Electrical Stimulation	2
What Causes Seizures in Neurocysticercosis?	2
Hit by a Smooth CD8: T-Cell Attack on Hippocampal Neurons Triggers Limbic Encephalitis and Epilepsy	2
A Cry for Survival? Rhythmic and Periodic EEG Discharges as Treatment Targets Following Cardiac Arrest	2
Do You Believe in Magic (Bullets)?	2
Flattening the Curve: Slowing Age-Accelerated Brain Atrophy With Epilepsy Surgery	2
Using the TTX Model to Better Understand the Pathophysiology of a DREADDed Epilepsy—Infantile (Epileptic) Spasms	2
The BEST Conceivable Way to Talk About Epilepsy Biomarkers	2
Mechanism-Based Treatment for Neonatal Seizures: Still on the Horizon	2
Modifiable Risk Factors of Dementia in Older Adults With Epilepsy: An Opportunity to Flatten the Curve?	2
Neuro2D Lies at the Nexus of Autism, Epilepsy, and Intellectual Disabilities	2
How to Help Your Patients Enroll in the New-Onset Refractory Status Epilepticus (NORSE) and Febrile Infection-Related Epilepsy Syndrome (FIRES) Family Registry, and Other Rare Epilepsy Registries	2
Epilepsy-Specific Anxiety: A Potential Clue to the Seizure Onset Zone	2
How Much GAD65 Do You Have? High Levels of GAD65 Antibodies in Autoimmune Encephalitis	2
Continuous EEG in ICU: Not a Luxury After All	2
The Search for Autoimmune-Associated Epilepsy Continues—Are We Getting Closer to Our Target?	2
Breaking Down the Wall: The Strategic Plan of Cancer to Conquer the Brain	2
Progressive Neuronal Loss in Epilepsy – A Long-Standing Conundrum Finally Resolved?	2
Sometimes, More Is More: Antiseizure Medication polytherapy Is Associated With Decreased SUDEP Risk	2
Epilepsy as a Disease of White Matter	2
Connectivity and Excitability Shape Seizure Circuits	2
Harnessing Metabolomics to Advance Epilepsy Research	2
Light, Kindling, Action! Brain-Wide Circuit Changes After Optogenetic Hippocampal Kindling Revealed by Functional Magnetic Resonance Imaging	2
Cheers for SANTĖ: Long Term Safety and Efficacy of Anterior Nucleus of the Thalamus DBS	2
SANAD II: Dear Levetiracetam, the Honeymoon Is Over	1
Mechanisms of Subiculum Hyperexcitability in Temporal Lobe Epilepsy	1
Does Deep Brain Stimulation Work in Lennox-Gastaut Syndrome? Well…it Depends	1
The State of Specialized Epilepsy Care in the States: Increased Access, New Tools, but the Same Dismal Underutilization of Epilepsy Surgery	1
Same Channel, Different Tune	1
Disrupted Spatial Maps in Epilepsy Highlight the Importance of Timing in Neural Codes	1
Balancing Safety and Independence for People With Epilepsy Under Threat of SUDEP	1
You Snooze You Seize: GABAergic Potentiation of Genetic Generalized Seizures During NREM	1
Breaking the Seizure Randomness Myth: Evidence for a Recurring Ebb and Flow of Seizure Risk on the Continuum of Time	1
Of Blobs and Buzzes: Does SISCOM Imaging Actually Help SEEG Planning?	1
Suicidality: Once Again, Don’t Blame the Drug Class	1
Seizing the Alzheimer’s Brain: A Role for Sirtuin 3 in Hyperexcitability	1
Don’t Hesitate to Vaccinate—The Safety of Covid-19 Vaccination and Epilepsy	1
Epilepsy Surgery in Childhood Versus Adulthood: What Are We Waiting for?	1
Optokindling, GABA Dwindling	1
Dendritic and Spine Loss in Epilepsy: What Seizures Got to Do With It?	1
Dynamic Fluorescence Imaging in Experimental Epilepsy	1
Should We Be Going With Our Patient’s Gut (Bacteria)? The Intestinal Microbiota and Epilepsy Treatments	1
Neuronal Superhubs: Elite Networks that Rule Synchrony	1
Parental Counseling About Sudden Unexpected Death in Epilepsy: Why, When, Where, What, Who, and How?	1
Transforming Glia to Neurons Effectively Treats Temporal Lobe Seizures	1
Deep Thoughts—Predicting Initial Treatment Response in Newly Diagnosed Epilepsy	1
Free as a BRD4: Bromodomain Inhibition Ameliorates Disease Phenotypes in a Model ofMECP2Deficiency and Is a Potential Therapy for Rett Syndrome	1
Lesional Epilepsy in Children: Removing Doubt to Cut It Out	1
Measure for Measure: Measuring the Usefulness of Measuring Antiseizure Medication Levels	1
Reoperations for Epilepsy: How Many Times Should We Bat?	1
Machine Learning to Address the Enigma of Temporal Lobe Epilepsy Lateralization	1
The Deep Breath Before the Plunge: Ictal Apnea and the Amygdala	1
Assessin’ the Vexin’ Connexin Between Severity of Epilepsy and Hippocampal Gliosis	1
Tuning the Wave: Controlling Spreading Depolarization with Activation/Inactivation of Kv7.2	1
Septal Signaling Suppresses Seizures Through Stimulating Somatostatin Cells	1
Will There Be a Seizure? Predicting Seizures in Children (and Adults) with Familial Cerebral Cavernous Malformations	1
Neuromodulation: The Search Is On for the Most Effective Parameters	1
Benzodiazepines for Out-of-Hospital Status Epilepticus: Do or Do Not! There Is No Try!	1
When Apnea Turns Terminal: When, How, Why?	1
2P or not 2P: The Question of Seizure Initiation	1
Neonatal Seizures: Providing Care With Evidence, Not Just Experience	1
Guardians of the Frequency: Neuronal Regulation by Microglia	1
Highlights From AES2020, a Virtual American Epilepsy Society Experience	1
Who Dunnit? Angiotensin, Inflammation, or Complement: Unresolved	1
More Than Reels: Cajal-Retzius Cells Become Active	1
You Can Teach an Old Drug New Tricks	1
Stopped At the Border: Cortical Spreading Depolarization Blocks Seizure Propagation	1
Breastfeeding and the Neurologist: An Important Role for Us	1
Epilepsy, Cardiovascular Risks, and Dementia: A Ménage à Trois	1
Treating Post-Traumatic Seizures to Limit Tau Accumulation in Larval Zebrafish	1
Adolescence and Epilepsy: The Perfect Storm for Suicidal Behavior	1
From the Subiculum to the Anterior Nuclei of the Thalamus: The Key to Hippocampal Seizure Generalization?	1
Leaky Blood–Brain Barrier: A Double Whammy for the Brain	1
Is STN Neuromodulation of Focal Motor Seizures Ready for Prime Time?	1

Keeping up with KCNQ2: A New Model of Epileptic Encephalopathy	1
That’s a Wrap: Could Controlling Activity-Regulated Myelination Prevent Absence Seizures?	1
Dollars and Sense: Cost-Effectiveness of Epilepsy Surgery	1
Is On-Demand Dynorphin Destined to Be in Demand to Decrease Seizures?	1
No Time to Die – Avoidable Death in Epilepsy	1
An Eye for an Eye: A Randomized Placebo-Controlled Trial of IVIG in Antibody-Mediated Encephalitis	1
Risky Business: Traumatic Brain Injury and Epilepsy	1
The Nose Knows: Intranasal Midazolam To Treat Acute Seizures During Inpatient Epilepsy Monitoring	1
Tele-Mental Connectivity: Pseudo-Therapy or The New Reality?	1
Seizure-Induced Neurogenesis: 1 Out of 3 Ain’t Bad	1
Stop the Lights—Turning Off the Electricity in Tuberous Sclerosis	1
Relationship Status Update on Astrocytic VEGFR-3 and mTOR Signaling: It’s Complicated	1
Entering the Era of Personalized Medicine in Epilepsy Through Neuroimaging Machine Learning	1
Epilepsy Research Now in 3D: Harnessing the Power of Brain Organoids in Epilepsy	1
To Not Sleep, Perchance to Seize	1
Targeting Epileptogenesis: A Conceptual Black Hole or Light at the End of the Tunnel?	1
Psychogenic Non-Epileptic Seizures 2020: The Enhanced Role of the Neurologist…	1
Reconsidering Network Mechanisms in Absence Seizures: Unhitching the Wave Cart From the Spike Horse	1
Slow Down and Seize: Seizures Triggered by Slow Wave Oscillations in a GABAergic Model of Dravet Syndrome	1
Sage Against the Machine: Promise and Challenge of Artificial Intelligence in Epilepsy	1
Microglial Cells in Epilepsy: Not That Bad After All?	1
Analysis of Blood DNA Methylation in Early-Life Seizures	1
ThalaMS: New Evidence Linking Epilepsy, Multiple Sclerosis, and the Thalamus	0
Catch the Rhythm!	0
Deep-Seated Interictal Epileptiform Activity: Another Reason to Lose Sleep	0
Slower, Fewer Hippocampal Ripples in Loss-of-Function Model of Dravet Syndrome	0
Erratum to Oops!…Glutamate Did it Again	0
Go Ahead! Use that Reperfusion Treatment, don’t Worry About Subsequent Seizures!	0
TLR4 Signaling Contributes to Post-Traumatic Epileptogenesis Through Insertion of Inwardly Rectifying AMPA Receptors: Not a Happy CP-AMPAR	0
The Temporal Lobe Club: Newer Approaches to Treat Temporal Lobe Epilepsy	0
The Value of Localizing Subclinical Seizures	0
One for All—Can We Have and Do We Want a First-Line Monotherapy for Epilepsy?	0
Seizing Off This Mortal Coil: A Matter of Epilepsy and Death	0
What Are the Chances That Epilepsy Surgery Will Allow My Child to Come Off Meds? Assessing Pediatric Epilepsy Surgery Outcomes: Data on ASM Freedom	0
Anti-Seizure Medications on Trial Again: Accused of Parkinson’s Disease!	0
Task-Specific Interictal Spiking: Adding to the Complexity	0
Structure-Function Properties in Sodium Channelopathies: Considerations for Targeted Therapy	0
Adult Gene Therapy for Epilepsy in a Model of Angelman Syndrome: Hope or Hype?	0
Choose Your Own Adventure: Expert Advice at Your Fingertips	0
Ictogenesis? That’s Random…..	0
Electroencephalographic Seizure or Electroencephalographic Status Epilepticus in the ICU? Is it Time to Focus Just on Electroencephalographic Status Epilepticus?	0
Registry-Based Phenotyping to Improve the Diagnosis of Autoimmune Encephalitis	0
What Matters to You? Looking Beyond Seizure Freedom Following Epilepsy Surgery	0
Family Ties: Reproductive Decision Making Among Members of Multiplex Epilepsy Families	0
Start Low and Go Slow: The General Principle of Managing Older Adults With Epilepsy Finds Robust Support From Frailty	0
Magnetic Resonance Imaging in Status Epilepticus: Useful Scrying Board or Expensive Stopwatch?	0
Open the Window for the Cure of Dravet	0
Unblock the Block! Preventing Inhibitory Failure to Maintain Inhibitory Restraint	0
Epilepsy Is Associated With Increased Long-Term Risk of Cardiac Arrhythmias: Did Your Heart Skip a Beat?	0
Erratum 22(1), 22(2), 22(3) and 22(4)	0
Illuminating Seizures: Combined Optical and Electrophysiological Recording Techniques Provide Novel Insights Into Seizure Dynamics	0
No Gain, Less Pain: GABRB3 Mutations in Epileptic Encephalopathy	0
The Double-Edged Sword: Are Endocannabinoids Doing More Harm than Good in Epilepsy?	0
Astrocytes Keep It Under Wraps: Reconstructing Synapses in the Latent Phase of Epileptogenesis	0
MicroRNA 335-5p: The Sodium Channel Silencer	0
Ictal Inhibition: Sync Globally, Slack Locally	0
Caution: Benzodiazepines in Pregnancy and Risk of Adverse Perinatal Outcomes	0
AI-nalyzing Mouse Behavior to Combat Epilepsy	0
Let’s Talk About Sex and Juvenile Myoclonic Epilepsy	0
Cannabidiol Keeps Hippocampal Hyperactivity in Check	0
Temporal Encephaloceles and Epileptogenicity: Does Size Matter?	0
In Epilepsy Surgery, Pathology Matters, and Lesions Need to Go	0
Is Node Disconnection the Key for Improving LITT Outcome?	0
What’s in Your Nomogram? Personalized Prognostication of Verbal Memory Decline after Temporal Lobe Resection in Adults With Epilepsy	0
A REST Paradox: Does it Control or Enhance Neural Activity?	0
Merging Art with Science: A Detection Score for Autoimmune Epilepsy	0
Raptor Preys on mTOR Imbalance in Tuberous Sclerosis	0
Threaded Structure of a Pathological Oblivion	0
Glutamate’s Secret Interictal Life	0
Watch Out for GATORs: Fasting, Seizures, and Nutrient Sensing	0
Anti-Epileptogenesis: Some Roads Lead to Losartan	0
Molecular Layer Heterotopia: Harmless Brain Warts or Ictal Main Force?	0
E-I E-I Woe: Mossy Cell Regulation of Granule Cell Activity in Temporal Lobe Epilepsy	0
Highlights From the Annual Meeting of the American Epilepsy Society 2022	0
Seizures and Cardiac Dysrhythmias: And the Beat (Sometimes) Goes On	0
Not a Slam-Dunk: Assessing the Role of EEG/fMRI in the Presurgical Evaluation	0
Ticktock—What Is the Seizure Driving Clock?	0
Closing the Loop for Precise Seizure Control	0
Adjunctive Use of Cannabidiol: A Joint Action to Patch Up Drug-Resistant Epilepsy	0
Unspooling the Thread: VIP Interneurons Linked With Autism Spectrum Disorder Behaviors but Not Seizures in Dravet Syndrome	0
Do Not Sleep on It! Prognosis of First-Ever Unprovoked Seizure From Sleep	0
Can a Mouse Help Us Unravel the Mysteries of CDKL5-Related Epilepsy?	0
The ECHO Was Heard Throughout the School	0
Communication Breakdown? The Perils and Opportunities of ASM Self-Discontinuation	0
SUDEP: A Local Low Pressure [pO2] System Makes It Hard to Breathe	0
Late-Onset Epilepsy: A Distinct Entity that Begins and Ends With the Associated Comorbidities	0
Pick Your Poison but Pick It Wisely: Choosing a Second-Line Medication for the Management of Status Epilepticus	0
Adult-Generated Dentate Granule Cells in Epilepsy: Loyal Gatekeepers or Evil Changelings?	0
Exploring the Cognitive Outcomes of Children Prenatally Exposed to Antiseizure Medications: Mind the Lab	0
Empowering With Rescue Therapy: A Rescue for More than Just Seizures	0
Bringing Statistics to the Clinic to Predict the Future: Nomograms for Psychiatric Outcomes of Epilepsy Surgery	0
Waiting to Inhale: Preventing Fatality From Seizure-Induced Apnea	0
Old Diagnostic Meets Newer Therapy; ECoG During LiTT	0
A Disciplined Approach to Treatment of Psychogenic Nonepileptic Seizures	0
Making Up Missed Anti-Seizure Medication Doses: Double or Nothing?	0