Cancer Cell

Papers
(The H4-Index of Cancer Cell is 111. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
TAMing immunity through an unexpected source3442
Olfactory neuroblastoma mimics molecular heterogeneity and lineage trajectories of small-cell lung cancer633
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression572
Hand in hand to successful immunotherapy: CD8+ T cells and M1-like macrophages swap the baton547
Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer527
Bnip3L is induced by p53 under hypoxia, and its knockdown promotes tumor growth503
EGFR-activated myofibroblasts promote metastasis of pancreatic cancer480
A snapshot of the earliest stages of hepatocellular carcinoma476
Characterization of the generic mutant p53-rescue compounds in a broad range of assays466
Accelerated approvals: Early-phase success or premature authorization?445
KIT as a therapeutic target in neuroendocrine prostate cancer411
Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas410
Dendritic cell redundancy enables priming of anti-tumor CD4+ T cells in pancreatic cancer379
Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling360
A stratification system for breast cancer based on basoluminal tumor cells and spatial tumor architecture349
Multimodal spatial-omics reveal co-evolution of alveolar progenitors and proinflammatory niches in progression of lung precursor lesions329
IL-36γ armored CAR T cells reprogram neutrophils to induce endogenous antitumor immunity319
Lymphoma accelerates T cell and tissue aging318
KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition308
Long-range cholinergic input promotes glioblastoma progression297
Dynamic circulating tumor DNA during chemoradiotherapy predicts clinical outcomes for locally advanced non-small cell lung cancer patients296
Diet-microbiome interactions in cancer294
Spatial profiling technologies illuminate the tumor microenvironment291
The aging lung microenvironment awakens melanoma metastases285
Impaired humoral immunity is associated with prolonged COVID-19 despite robust CD8 T cell responses269
T cell dynamism and immune-related adverse events257
A Lymphotoxin-Driven Pathway to Hepatocellular Carcinoma249
Challenges in neoantigen-directed therapeutics245
Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target239
Targeting P4HA1 promotes CD8+ T cell progenitor expansion toward immune memory and systemic anti-tumor immunity237
Elucidating acquired PARP inhibitor resistance in advanced prostate cancer236
Multiomic analysis reveals conservation of cancer-associated fibroblast phenotypes across species and tissue of origin235
B cell heterogeneity in cancer comes of age235
Cancer vaccines226
Bacteria in metastatic sites: Unveiling hidden players in cancer progression221
T-Lymphoblastic Lymphoma Cells Express High Levels of BCL2, S1P1, and ICAM1, Leading to a Blockade of Tumor Cell Intravasation218
When the methylome becomes the microscope218
Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS215
Immune biomarkers of response to immunotherapy in patients with high-risk smoldering myeloma214
Intratumoral immune triads are required for immunotherapy-mediated elimination of solid tumors214
Sensory neurons drive pancreatic cancer progression through glutamatergic neuron-cancer pseudo-synapses211
Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer208
Fusobacterium nucleatum facilitates anti-PD-1 therapy in microsatellite stable colorectal cancer208
Identification of cycling regulatory T cell precursors as conductors of immune escape during breast carcinoma progression204
High endothelial venules in cancer: Regulation, function, and therapeutic implication202
Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer201
A holistic view of cancer201
Spatiotemporal single-cell analysis decodes cellular dynamics underlying different responses to immunotherapy in colorectal cancer199
Prior anti-CTLA-4 therapy impacts molecular characteristics associated with anti-PD-1 response in advanced melanoma194
Targeting STING to generate therapeutic anti-tumor immunity194
Gut microbes promote chemoradiotherapy resistance via metabolic cross-feeding193
Are we ready to look beyond plasma cells in assessing high-risk smoldering myeloma?193
A genetic portrait of metastatic seeds in lung adenocarcinoma193
Tumor-directed dysregulation of erythroid progenitors drives immunosuppressive myeloid cells190
Distinct T cell functions enable efficient immunoediting and prevent tumor emergence of developing sarcomas188
Revisiting TNM staging for EBV-related nasopharyngeal carcinoma185
The one-two punch: TIM-3 blockade targets immune and tumor cells to knock out pediatric brain tumors182
Challenges and opportunities for modeling aging and cancer181
Immunosensitivity cuts across mismatch repair status in colorectal cancer181
Spatial proteo-transcriptomic profiling reveals the molecular landscape of borderline ovarian tumors and their invasive progression180
Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts180
Evolutionary landscape of clonal hematopoiesis in 3,359 individuals from the general population175
Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma175
Neutralizing IL-8 potentiates immune checkpoint blockade efficacy for glioma174
Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer170
Immunotherapy-activated T cells recruit and skew late-stage activated M1-like macrophages that are critical for therapeutic efficacy168
Temporal evolution reveals bifurcated lineages in aggressive neuroendocrine small cell prostate cancer trans-differentiation168
Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation166
Clinical significance and biology of circulating tumor DNA in high-risk early-stage HER2-negative breast cancer receiving neoadjuvant chemotherapy165
Conserved spatial subtypes and cellular neighborhoods of cancer-associated fibroblasts revealed by single-cell spatial multi-omics163
Multi-omic profiling of follicular lymphoma reveals changes in tissue architecture and enhanced stromal remodeling in high-risk patients163
Integrated single-cell and spatial transcriptomics uncover distinct cellular subtypes involved in neural invasion in pancreatic cancer163
Hypoxia inducible factor-1α drives cancer resistance to cuproptosis159
A conserved, terminal, pro-tumor neutrophil population158
Ubiquitin control of cytosolic DNA sets immune responses to DNA damage158
Response-based molecular subtyping—emergence of the third generation of breast cancer subtypes158
Framework for cancer evolution profiling and interception in colorectal cancer: ASCEND-CRC program157
Tumor sequencing of African ancestry reveals differences in clinically relevant alterations across common cancers156
Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1151
Tumor-intrinsic SIRPA promotes sensitivity to checkpoint inhibition immunotherapy in melanoma151
T cell extracellular vesicles go nuclear to turn cold tumors hot150
Interleukin-21 engineering enhances NK cell activity against glioblastoma via CEBPD150
Circulating tumor DNA as a biomarker in early phase clinical trials150
Knowledge-enhanced pretraining for vision-language pathology foundation model on cancer diagnosis148
Tumor-infiltrating lymphocytes: A new hope148
Immune determinants of the pre-metastatic niche148
Tumor-resident Lactobacillus iners confer chemoradiation resistance through lactate-induced metabolic rewiring147
Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment146
Midkine as a driver of age-related changes and increase in mammary tumorigenesis142
Characterization of a pathogenic subpopulation of human glioma associated macrophages linked to glioma progression137
Integrated proteogenomic characterization of glioblastoma evolution136
Single-cell multi-stage spatial evolutional map of esophageal carcinogenesis135
A path to translation: How 3D patient tumor avatars enable next generation precision oncology134
A circular RNA in neuroendocrine carcinomas133
Precise patient stratification in esophageal cancer: Biomarkers for immunochemotherapy133
Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness133
GDF15 research from bench to bedside132
Taxanes directly induce T cell cytotoxic extracellular vesicles to eradicate tumor cells129
Firing up neutrophil anti-tumor immunity with cocktails126
T cell immune deficiency rather than chromosome instability predisposes patients with short telomere syndromes to squamous cancers125
Risk factors for poor humoral response to primary and booster SARS-CoV-2 vaccination in hematologic and oncological outpatients—COVIDOUT study125
JYP0322, a highly selective and brain-penetrant ROS1 inhibitor, overcomes ROS1G2032R resistance mutation in NSCLC: The first-in-human phase 1 trial124
Tumors on different wavelengths124
New horizons at the interface of artificial intelligence and translational cancer research124
Effect of neoadjuvant chemoradiotherapy with or without PD-1 antibody sintilimab in pMMR locally advanced rectal cancer: A randomized clinical trial123
The winner takes it all: Competition drives clonal selection in gliomagenesis122
IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma119
Distinct spatiotemporal dynamics of CD8+ T cell-derived cytokines in the tumor microenvironment118
A tumor-associated photoreceptor signature unifies distinct central nervous system malignancies117
CSF1R+ myeloid-monocytic cells drive CAR-T cell resistance in aggressive B cell lymphoma117
Exercise-induced engagement of the IL-15/IL-15Rα axis promotes anti-tumor immunity in pancreatic cancer116
Progenitor-like exhausted SPRY1+CD8+ T cells potentiate responsiveness to neoadjuvant PD-1 blockade in esophageal squamous cell carcinoma111
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