Cancer Cell

Papers
(The H4-Index of Cancer Cell is 101. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-02-01 to 2024-02-01.)
ArticleCitations
Oxidative Stress in Cancer1119
m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer618
A Probabilistic Classification Tool for Genetic Subtypes of Diffuse Large B Cell Lymphoma with Therapeutic Implications551
Conserved pan-cancer microenvironment subtypes predict response to immunotherapy450
Intratumor Heterogeneity: The Rosetta Stone of Therapy Resistance442
The Challenges of Tumor Mutational Burden as an Immunotherapy Biomarker438
Acquired Resistance to Immune Checkpoint Inhibitors409
Overcoming Endocrine Resistance in Breast Cancer379
Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities375
Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion358
Engineering CAR-T Cells for Next-Generation Cancer Therapy312
Proteogenomic and metabolomic characterization of human glioblastoma293
The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes279
Clinical Challenges of Immune Checkpoint Inhibitors270
Seroconversion rates following COVID-19 vaccination among patients with cancer264
Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer253
Challenges and Opportunities for Pancreatic Cancer Immunotherapy252
Molecular Subsets in Renal Cancer Determine Outcome to Checkpoint and Angiogenesis Blockade248
Single-cell analyses reveal key immune cell subsets associated with response to PD-L1 blockade in triple-negative breast cancer248
Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma244
MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate243
Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer240
Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments236
Targeting the MAPK Pathway in KRAS-Driven Tumors234
Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma232
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth229
Response and Resistance to BCR-ABL1-Targeted Therapies229
Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation226
Integrated Molecular and Clinical Analysis of 1,000 Pediatric Low-Grade Gliomas224
CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4222
Progressive immune dysfunction with advancing disease stage in renal cell carcinoma218
Antibody response to SARS-CoV-2 vaccines in patients with hematologic malignancies213
Emerging Roles for Branched-Chain Amino Acid Metabolism in Cancer212
Liquid Biopsy-Based Biomarkers of Treatment Response and Resistance209
Nivolumab Plus Ipilimumab for Metastatic Castration-Resistant Prostate Cancer: Preliminary Analysis of Patients in the CheckMate 650 Trial207
Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells197
Emergence of a High-Plasticity Cell State during Lung Cancer Evolution196
Targeting cell-cycle machinery in cancer188
YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis187
Mechanisms of Sensitivity and Resistance to CDK4/6 Inhibition185
Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma183
SARS-CoV-2 Viral Load Predicts Mortality in Patients with and without Cancer Who Are Hospitalized with COVID-19183
Microbiome and cancer182
Immunogenicity of SARS-CoV-2 messenger RNA vaccines in patients with cancer181
COVID-19 and Cancer: Current Challenges and Perspectives181
Identifying and Targeting Human Tumor Antigens for T Cell-Based Immunotherapy of Solid Tumors177
Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma174
Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer169
Advancing Cancer Research and Medicine with Single-Cell Genomics169
Immunometabolic Interplay in the Tumor Microenvironment167
Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy167
Highly variable SARS-CoV-2 spike antibody responses to two doses of COVID-19 RNA vaccination in patients with multiple myeloma165
Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver163
Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer156
Single-cell lineage tracing of metastatic cancer reveals selection of hybrid EMT states155
Toripalimab plus chemotherapy in treatment-naïve, advanced esophageal squamous cell carcinoma (JUPITER-06): A multi-center phase 3 trial154
Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma149
Biomolecular Condensates and Cancer148
Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity145
Single-cell dissection of cellular components and interactions shaping the tumor immune phenotypes in ovarian cancer145
Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade145
Comprehensive Analysis of Genetic Ancestry and Its Molecular Correlates in Cancer143
Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification143
The Glioma Stem Cell Model in the Era of Single-Cell Genomics142
Mutant p53 suppresses innate immune signaling to promote tumorigenesis141
DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity140
Effect of ibrutinib with R-CHOP chemotherapy in genetic subtypes of DLBCL140
Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer139
Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations138
Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma133
Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer133
IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis133
Single-Cell Multiomics Sequencing Reveals Prevalent Genomic Alterations in Tumor Stromal Cells of Human Colorectal Cancer132
KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer131
Genomic and Transcriptomic Characterization of Natural Killer T Cell Lymphoma129
Visualizing Synaptic Transfer of Tumor Antigens among Dendritic Cells129
Single-Cell Characterization of Malignant Phenotypes and Developmental Trajectories of Adrenal Neuroblastoma129
Intratumoral plasma cells predict outcomes to PD-L1 blockade in non-small cell lung cancer128
Integrated Omics of Metastatic Colorectal Cancer128
Immunomodulation by targeted anticancer agents125
An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence124
Artificial intelligence for clinical oncology124
Antibody and T cell immune responses following mRNA COVID-19 vaccination in patients with cancer122
Durvalumab with olaparib and paclitaxel for high-risk HER2-negative stage II/III breast cancer: Results from the adaptively randomized I-SPY2 trial120
ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis120
Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site119
Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer118
Commensal bacteria and fungi differentially regulate tumor responses to radiation therapy114
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma114
Immune phenotypic linkage between colorectal cancer and liver metastasis113
The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer113
Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer111
The loss of RNA N6-adenosine methyltransferase Mettl14 in tumor-associated macrophages promotes CD8+ T cell dysfunction and tumor growth111
Tumor organoids: Opportunities and challenges to guide precision medicine111
Activating a collaborative innate-adaptive immune response to control metastasis111
Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity107
The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells106
Proteogenomic characterization identifies clinically relevant subgroups of intrahepatic cholangiocarcinoma105
SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways103
Functional precision oncology: Testing tumors with drugs to identify vulnerabilities and novel combinations102
N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation101
Extensive Remodeling of the Immune Microenvironment in B Cell Acute Lymphoblastic Leukemia101
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