OOIR: Observatory of International Research

Papers

(The TQCC of Experimental Biology and Medicine is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Participation of ASK-1 in the cardiomyocyte-protective role of mechanical ventilation in a rat model of myocardial infarction	104
Paraoxonase 1 rs662 polymorphism, its related variables, and COVID-19 intensity: Considering gender and post-COVID complications	44
Green synthesized silver nanoparticles for the treatment of diabetes and the related complications of hyperlipidemia and oxidative stress in diabetic rats	38
Roles of IL-33 in the Pathogenesis of Cardiac Disorders	38
Circulating exosomal microRNA-4497 as a potential biomarker for metastasis and prognosis in non-small-cell lung cancer	38
Wogonin, as a potent anticancer compound: From chemistry to cellular interactions	34
Bioinformatics analysis of the genes associated with co-occurrence of heart failure and lung cancer	33
Mild hypobaric hypoxia influences splenic proliferation during the later phase of stress erythropoiesis	32
Dual detection of COVID-19 antigens and antibodies using nanoscale fluorescent plasmonic substrates	32
The influence of multidisciplinary team clinic on the prognosis of patients with chronic kidney disease	31
The continuing evolution of barcode applications: Functional toxicology to cell lineage	31
Autotaxin–lysophosphatidic acid receptor 5 axis evokes endothelial dysfunction via reactive oxygen species signaling	29
Classification of salivary bacteriome in asymptomatic COVID-19 cases based on long-read nanopore sequencing	29
Combining tissue clearing and Fluoro-Jade C labeling for neurotoxicity assessments	29
Data science in drug discovery safety: Challenges and opportunities	28
Gentiopicroside alleviates acute myocardial infarction injury in rats by disrupting Nrf2/NLRP3 signaling	28
A primordial target: Mitochondria mediate both primary and collateral anesthetic effects of volatile anesthetics	26
Indoxyl sulfate impairs in vitro erythropoiesis by triggering apoptosis and senescence	26
S-allylmercapto-N-acetylcysteine protects bone cells from oxidation and improves femur microarchitecture in healthy and diabetic mice	26
Exogenous surfactant reduces inflammation and redox imbalance in rats under prone or supine mechanical ventilation	24
Retraction Notice	24
Structural and molecular biology of Sabiá virus	24
Phenotyping in clinical text with unsupervised numerical reasoning for patient stratification	24
Interleukin-10 regulates starvation-induced autophagy through the STAT3-mTOR-p70s6k axis in hepatic stellate cells	24
Assessments of tumor mutational burden estimation by targeted panel sequencing: A comprehensive simulation analysis	24

Serum homocysteine is a valuable marker for predicting aggravation of infection in intestinal obstruction patients	24
Explainable hierarchical clustering for patient subtyping and risk prediction	23
Classifying and evaluating fetuses with multicystic dysplastic kidney in etiologic studies	22
Fluoride induces osteoblast autophagy by inhibiting the PI3K/AKT/mTOR signaling pathway in vivo and in vitro	22
Gene expression profile suggests different mechanisms underlying sporadic and familial mesial temporal lobe epilepsy	22
TBX1 regulates myogenic differentiation by activating the TGFβ-Smad2/3 pathway in myoblasts	21
Inferences of carboplatin response-related signature by integrating multiomics data in ovarian serous cystadenocarcinoma	20
Statistical considerations for outcomes in clinical research: A review of common data types and methodology	20
Thermo- and pH-sensitive nanoparticles of poly (N-isopropylacrylamide-decenoic acid-1-vinylimidazole) for ultrasound switchable fluorescence imaging	20
Evaluation of the mechanisms of heme-induced tissue factor activation: Contribution of innate immune pathways	20
The role of IL-33/ST2 signaling in the tumor microenvironment and Treg immunotherapy	19
Arbovirus surveillance in mosquitoes: Historical methods, emerging technologies, and challenges ahead	19
Beclin1- and Atg13-dependent autophagy activation and morroniside have synergistic effect on osteoblastogenesis	19
Macrophage polarization in hypoxia and ischemia/reperfusion: Insights into the role of energetic metabolism	19
In-ovo imaging using ostrich eggs: Biomagnetism for detection of cardiac signals and embryonal motion	19
Dysregulation of multiple signaling pathways: A possible cause of cerebral palsy	19
Expression of cytoskeleton-associated protein 4 is associated with poor prognosis and metastasis in nasopharyngeal carcinoma	18
Mechanisms of disease-associated SINE-VNTR-Alus	18
Corrigendum	18
Review on ultrasound-guided photoacoustic imaging for complementary analyses of biological systems in vivo	18
A novel fluorescent traceable carbon quantum dots with selective antibacterial activity against Porphyromonas gingivalis	18
Rhubarb extract rebuilding the mucus homeostasis and regulating mucin-associated flora to relieve constipation	18
Artificial neural network–based diagnostic models for lung cancer combining conventional indicators with tumor markers	18
Manipulation of unfolded protein response by zoonotic vaccinia virus strains Guarani P1 and Passatempo	18
JAK inhibitors for the treatment of VEXAS syndrome	17
Hydroxytyrosol produced by engineered Escherichia coli strains activates Nrf2/HO-1 pathway: An in vitro and in vivo study	17
Tastin promotes non-small-cell lung cancer progression through the ErbB4, PI3K/AKT, and ERK1/2 pathways	17
Synthesis of glycine from 4-hydroxyproline in tissues of neonatal pigs	17
GDF15plays a critical role in insulin secretion in INS-1 cells and human pancreatic islets	17
The contribution of the immune system to genitourinary fibrosis	17
Maternal serum-derived exosomal lactoferrin as a marker in detecting and predicting ventricular septal defect in fetuses	17
Dapagliflozin-entresto protected kidney from renal hypertension via downregulating cell-stress signaling and upregulating SIRT1/PGC-1α/Mfn2-medicated mitochondrial homeostasis	17
LOXL2 reduces 5-FU sensitivity through the Hedgehog/BCL2 signaling pathway in colorectal cancer	17
The inducible prostaglandin E synthase (mPGES-1) in neuroinflammatory disorders	16
Effect of smoking on the redox status of knee osteoarthritis: A preliminary study	16
Repurposing medications for treatment of age-related macular degeneration: Insights from novel approaches to data mining	16
Visceral fat sympathectomy ameliorates systemic and local stress response related to chronic sleep restriction	15
Plasma Galectin-3 and H-FABP correlate with poor physical performance in patients with congestive heart failure	15
The dengue virus 4 component of NIAID’s tetravalent TV003 vaccine drives its innate immune signature	15
Alpha-linolenic acid enhances the facilitation of GABAergic neurotransmission in the BLA and CA1	15
Metformin inhibits mitochondrial dysfunction and apoptosis in cardiomyocytes induced by high glucose via upregulating AMPK activity	14
Respiratory viral infection and resolution of inflammation: Roles for specialized pro-resolving mediators	14
An increase in polyadenylation of histone isoforms, Hist1h2ah and Hist2h3c2, is governed by 3′-UTR in de-differentiated and undifferentiated hepatocyte	14
Analyses of lung cancer-derived volatiles in exhaled breath and in vitro models	13
Comparative transcriptome analysis of endothelial progenitor cells of HbSS patients with and without proliferative retinopathy	13
Seasonal variation and disease distribution of cytophagocytic mononuclear cells in synovial fluid: A medical record study	13
RxBERT: Enhancing drug labeling text mining and analysis with AI language modeling	13
Epstein-Barr virus genotype-1 and Mediterranean + strain in gastric cancer biopsies of Ghanaian patients	13
Revolutionized virome research using systems microbiology approaches	13
Elevated SARS-CoV-2 in peripheral blood and increased COVID-19 severity in American Indians/Alaska Natives	13

Aedes-borne orthoflavivirus infections in neotropical primates – Ecology, susceptibility, and pathogenesis	12
COVID-19 active case findings based on self-collected saliva samples with CRISPR-Cas12a detection	12
How S100B crosses brain barriers and why it is considered a peripheral marker of brain injury	12
Proteomics analysis of carotid body tumor revealed potential mechanisms and molecular differences among Shamblin classifications	12
Allele-specific silencing by RNAi of R92Q and R173W mutations in cardiac troponin T	12
Deep learning diagnostic performance and visual insights in differentiating benign and malignant thyroid nodules on ultrasound images	12
The β-catenin/CBP signaling axis participates in sepsis-induced inflammatory lung injury	12
Apelin-13 prevents the effects of oxygen–glucose deprivation/reperfusion on bEnd.3 cells by inhibiting AKT–mTOR signaling	12
Therapeutic effects of kartogenin on temporomandibular joint injury by activating the TGF-β/SMAD pathway in rats	12
Applied artificial intelligence in healthcare: Listening to the winds of change in a post-COVID-19 world	12
A quantum-based oversampling method for classification of highly imbalanced and overlapped data	12
New and effective method to develop primary hepatocytes from liver cancer patients	11
Resistin stimulates PC-3 prostate cancer cell growth through stimulation of SOCS3 and SOCS5 genes	11
Eugenol alleviates neuronal damage via inhibiting inflammatory process against pilocarpine-induced status epilepticus	11
Molecular and environmental contributors to neurological complications in sickle cell disease	11
Vagal milieu or electrophysiologic substrate? The link between atrial fibrillation and obstructive sleep apnea	11
Quantification of biomechanical properties of human corneal scar using acoustic radiation force optical coherence elastography	11
Diagnostic and prognostic nomograms for newly diagnosed intrahepatic cholangiocarcinoma with brain metastasis: A population-based analysis	11
Changes in gene expression and neuroinflammation in the hippocampus of rats with poststroke cognitive impairment	11
Single-cell RNA sequencing reveals differential expression of EGFL7 and VEGF in giant-cell tumor of bone and osteosarcoma	11
Antibiotic impregnation and nanocoating of external ventricular drainage catheters for antibacterial applications: Evaluation of in vitro studies and molecular docking	11
TRIM28 suppresses cancer stem-like characteristics in gastric cancer cells through Wnt/β-catenin signaling pathways	11
MicroRNA 205-5p and COVID-19 adverse outcomes: Potential molecular biomarker and regulator of the immune response	11
Influence of polymorphic variations of IFNL, HLA, and IL-6 genes in severe cases of COVID-19	11
Penicillin-binding protein (PBP) inhibitor development: A 10-year chemical perspective	11
Association between serum placental growth factor and vascular endothelial function in hyprtensive disorders complicating pregnancy	11
Improved protocol for Bst polymerase and reverse transcriptase production and application to a point-of-care diagnostics system	10
CRISPR/SaCas9-based gene editing rescues photoreceptor degeneration throughout a rhodopsin-associated autosomal dominant retinitis pigmentosa mouse model	10
GP5 regulates epithelial–mesenchymal transition in breast cancer via the PI3K/AKT signaling pathway	10
Na⁺/K⁺-ATPase DR region antibody ameliorated cardiac hypertrophy and fibrosis in rats with 5/6 nephrectomy	10
Recombinant antigen delivery to dendritic cells as a way to improve vaccine design	10
Comparison of circulating bacterial profiles between mild and severe COVID-19 patients	10
Role of follistatin-like protein 1 in liver diseases	10
Delayed tezampanel and caramiphen treatment but not midazolam protects against long-term neuropathology after soman exposure	10
Data-driven approach to quantify trust in medical devices using Bayesian networks	10
Isotyping and quantitation of the humoral immune response to SARS-CoV-2	10
Progress in the contrary effects of glucagon-like peptide-1 and chemerin on obesity development	10