Experimental Biology and Medicine

Article	Citations
Whole-genome analysis and evolutionary characterization of cervical and oral human papillomavirus 16	976500490
Decision rules for personalized statin treatment prescriptions over multi-objectives	154613513
Corrigendum to “CTRP3 protects against uric acid-induced endothelial injury by inhibiting inflammation and oxidase stress in rats”	154284082
Influence of glutamate and GABA transport on brain excitatory/inhibitory balance	68
A generative adversarial network for artifact removal in photoacoustic computed tomography with a linear-array transducer	59
Detection of severe acute respiratory syndrome coronavirus 2 and influenza viruses based on CRISPR-Cas12a	52
Hypoxic tumor microenvironment: Implications for cancer therapy	46
Going with the grain: Fiber, cognition, and the microbiota-gut-brain-axis	46
Current perspectives on the cellular and molecular features of epigenetic ageing	43
Cancer and stem cells	39
A mini-review on the effects of COVID-19 on younger individuals	37
The role of extracellular matrix in normal and pathological pregnancy: Future applications of microphysiological systems in reproductive medicine	35
The impact of the COVID-19 infection in dentistry	34
Epigallocatechin gallate decreases plasma triglyceride, blood pressure, and serum kisspeptin in obese human subjects	33
Gallic acid enhances reproductive function by modulating oxido-inflammatory and apoptosis mediators in rats exposed to aflatoxin-B1	33
Nitric oxide modulation in neuroinflammation and the role of mesenchymal stem cells	33
Prevalence of class I–III BRAF mutations among 114,662 cancer patients in a large genomic database	32
Is periodontal disease a risk factor for developing severe Covid-19 infection? The potential role of Galectin-3	32
Gallic acid and omega-3 fatty acids decrease inflammatory and oxidative stress in manganese-treated rats	31
Nicorandil inhibits TLR4/MyD88/NF-κB/NLRP3 signaling pathway to reduce pyroptosis in rats with myocardial infarction	30
CD9, a tetraspanin target for cancer therapy?	30
Regression from prediabetes to normal glucose regulation: State of the science	29
Circular RNA circ-CDYL sponges miR-1180 to elevate yes-associated protein in multiple myeloma	29
The amount of cytokine-release defines different shades of Sars-Cov2 infection	28
Breast cancer in sub-Saharan Africa: The current state and uncertain future	27

COVID-19 global pandemic planning: Decontamination and reuse processes for N95 respirators	27
Direct on-the-spot detection of SARS-CoV-2 in patients	27
An overview of neuroblastoma cell lineage phenotypes andin vitromodels	27
Copper promotion of myocardial regeneration	25
Overdosing on iron: Elevated iron and degenerative brain disorders	25
Role of the mitochondrial stress response in human cancer progression	25
Dysregulation of brain dopamine systems in major depressive disorder	25
Exosomes derived from synovial fibroblasts under hypoxia aggravate rheumatoid arthritis by regulating Treg/Th17 balance	25
Role of inflammatory markers in corona virus disease (COVID-19) patients: A review	23
Liquiritigenin decreases tumorigenesis by inhibiting DNMT activity and increasing BRCA1 transcriptional activity in triple-negative breast cancer	23
Suppression of HDAC by sodium acetate rectifies cardiac metabolic disturbance in streptozotocin–nicotinamide-induced diabetic rats	23
The effect of ultrasound cavitation on endothelial cells	22
Transcriptomic profiles in Parkinson’s disease	21
Role of sex hormones in lung cancer	21
Endothelin-1 in portal hypertension: The intricate role of hepatic stellate cells	21
Resveratrol alleviates alveolar epithelial cell injury induced by hyperoxia by reducing apoptosis and mitochondrial dysfunction	21
Novel 2019 coronavirus: Genome structure, clinical trials, and outstanding questions	20
Emerging technologies and their impact on regulatory science	20
Role of myokines and osteokines in cancer cachexia	20
The multifunctionality of expression systems in Bacillus subtilis: Emerging devices for the production of recombinant proteins	19
Secretory phospholipase A2 in SARS-CoV-2 infection and multisystem inflammatory syndrome in children (MIS-C)	19
Protease-activated receptor 1 as a potential therapeutic target for COVID-19	19
Secondary hemophagocytic lymphohistiocytosis versus cytokine release syndrome in severe COVID-19 patients	19
Photoacoustic imaging systems based on clinical ultrasound platform	19
Machine learning in optical coherence tomography angiography	18
Imaging and artificial intelligence for progression of age-related macular degeneration	18
Silicon: A neglected micronutrient essential for bone health	18
12 Survival-related differentially expressed genes based on the TARGET-osteosarcoma database	18
Bacterial microbiota in upper respiratory tract of COVID-19 and influenza patients	18
Mesenchymal stem cells maintain the stemness of colon cancer stem cells via interleukin-8/mitogen-activated protein kinase signaling pathway	18
Overcoming physiological barriers by nanoparticles for intravenous drug delivery to the lymph nodes	18
COVID-19: Time for precision epidemiology	18
Circulating serum exosomal miR-20b-5p and miR-3187-5p as efficient diagnostic biomarkers for early-stage non-small cell lung cancer	17
Angiogenic and anti-inflammatory properties of azadirachtin A improve random skin flap survival in rats	17
Innovative approaches for treatment of osteosarcoma	17
Genomic analysis of SARS-CoV-2 reveals local viral evolution in Ghana	16
Pathology and pathogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)	16
NAD metabolism in aging and cancer	16
Therapeutically leveraging GABAA receptors in cancer	16
IL-17A is involved in diabetic inflammatory pathogenesis by its receptor IL-17RA	16
SARS-CoV-2 variants: A double-edged sword?	16
Metformin and retinal diseases in preclinical and clinical studies: Insights and review of literature	16
Chemokine-like factor 1: A promising therapeutic target in human diseases	15
Fast intrinsic optical signal correlates with activation phase of phototransduction in retinal photoreceptors	15
Circulating LIPCAR is a potential biomarker of heart failure in patients post-acute myocardial infarction	15
Calliandra portoricensisameliorates ovarian and uterine oxido-inflammatory responses inN-methyl-N-nitrosourea and benzo[a]pyrene-treated rats	15
Rapid and ultrasensitive detection of circulating human papillomavirus E7 cell-free DNA as a cervical cancer biomarker	15
Regulation of Th1/Th2 and Th17/Treg by pDC/mDC imbalance in primary immune thrombocytopenia	15
A GM1 gangliosidosis mutant mouse model exhibits activated microglia and disturbed autophagy	15
Long non-coding RNA IGF2-AS represses breast cancer tumorigenesis by epigenetically regulating IGF2	15

FOXM1 activates JAK1/STAT3 pathway in human osteoarthritis cartilage cell inflammatory reaction	15
The WWOX gene in brain development and pathology	14
The “ideal protein” concept is not ideal in animal nutrition	14
Tackling rare diseases: Clinical trials on chips	14
Hypoxic colorectal cancer-secreted exosomes deliver miR-210-3p to normoxic tumor cells to elicit a protumoral effect	14
Functional intrinsic optical signal imaging for objective optoretinography of human photoreceptors	14
CircFADS2: A potential prognostic biomarker of colorectal cancer	14
Single-cell RNA sequencing reveals differential expression of EGFL7 and VEGF in giant-cell tumor of bone and osteosarcoma	14
KDM1A and KDM3A promote tumor growth by upregulating cell cycle-associated genes in pancreatic cancer	13
CCNB1 promotes the development of hepatocellular carcinoma by mediating DNA replication in the cell cycle	13
SNHG1 represses the anti-cancer roles of baicalein in cervical cancer through regulating miR-3127-5p/FZD4/Wnt/β-catenin signaling	13
Adipose-derived stem cells in ovarian cancer progression, metastasis, and chemoresistance	13
Carbon “quantum” dots for bioapplications	13
Inflammatory response and matrix metalloproteinases in chronic kidney failure: Modulation by adropin and spexin	13
Importance of extracellular vesicles in hypertension	13
Arbutin ameliorates glucocorticoid-induced osteoporosis through activating autophagy in osteoblasts	13
Interpretation of anatomic correlates of outer retinal bands in optical coherence tomography	13
Hyperinflammation after anti-SARS-CoV-2 mRNA/DNA vaccines successfully treated with anakinra: Case series and literature review	12
The use of DNA methylation clock in aging research	12
Convalescent serum-derived exosomes: Attractive niche as COVID-19 diagnostic tool and vehicle for mRNA delivery	12
WNT signaling in atrial fibrillation	12
Role of hyperoxic treatment in cancer	12
Fungal infection risks associated with the use of cytokine antagonists and immune checkpoint inhibitors	12
Minireview: Insights into anti-interferon-γ autoantibodies	12
Identification of potential lipid biomarkers for active pulmonary tuberculosis using ultra-high-performance liquid chromatography-tandem mass spectrometry	12
Biological evidence to define a vitamin A deficiency cutoff using total liver vitamin A reserves	12
Pulmonary gene delivery—Realities and possibilities	12
Gene signature and prognostic merit of M6a regulators in colorectal cancer	12
E2F3 drives the epithelial-to-mesenchymal transition, cell invasion, and metastasis in breast cancer	12
The antifibrotic role of natural killer cells in liver fibrosis	12
Sigh maneuver protects healthy lungs during mechanical ventilation in adult Wistar rats	12
Whole-genome sequencing as a first-tier diagnostic framework for rare genetic diseases	12
Survival stratification for colorectal cancer via multi-omics integration using an autoencoder-based model	12
Mitophagy promotes the stemness of bone marrow-derived mesenchymal stem cells	12
Irisin induces white adipose tissue browning in mice as assessed by magnetic resonance imaging	12
Simultaneous visible light optical coherence tomography and near infrared OCT angiography in retinal pathologies: A case study	11
The role of inflammation in driving left ventricular remodeling in a pre-HFpEF model	11
Acupuncture reduces pain in rats with osteoarthritis by inhibiting MCP2/CCR2 signaling pathway	11
Osteopontin as a biomarker for COVID-19 severity and multisystem inflammatory syndrome in children: A pilot study	11
The implications of neutrophil extracellular traps in the pathophysiology of atherosclerosis and atherothrombosis	11
Microengineered systems with iPSC-derived cardiac and hepatic cells to evaluate drug adverse effects	11
Telomere length in different metabolic categories: Clinical associations and modification potential	11
Inhibitory effect of hydnocarpin D on T-cell acute lymphoblastic leukemia via induction of autophagy-dependent ferroptosis	11
Prediction of ovarian aging using ovarian expression of BMP15, GDF9, and C-KIT	11
Neferine induces mitochondrial dysfunction to exert anti-proliferative and anti-invasive activities on retinoblastoma	11
Variable number tandem repeats – Their emerging role in sickness and health	11
IL-25/IL-33/TSLP contributes to idiopathic pulmonary fibrosis: Do alveolar epithelial cells and (myo)fibroblasts matter?	11
Effect of vitamin D3 supplementation on hepatic lipid dysregulation associated with autophagy regulatory AMPK/Akt-mTOR signaling in type 2 diabetic mice	11
Lipocalin-2, S100A8/A9, and cystatin C: Potential predictive biomarkers of cardiovascular complications in COVID-19	11
Are insulin-resistance and oxidative stress cause or consequence of aging	10
Sickle cell disease as an accelerated aging syndrome	10
H2S attenuates oxidative stress via Nrf2/NF-κB signaling to regulate restenosis after percutaneous transluminal angioplasty	10
Modern approaches on stem cells and scaffolding technology for osteogenic differentiation and regeneration	10
Alternative splicing of leptin receptor overlapping transcript in osteosarcoma	10
Treatment of osteoporosis with a modified zeolite shows beneficial effects in an osteoporotic rat model and a human clinical trial	10
The role of chest computed tomography in the management of COVID-19: A review of results and recommendations	10
Cucurbitacin B and cisplatin induce the cell death pathways in MB49 mouse bladder cancer model	10
Clinical applications of 3D normal and breast cancer organoids: A review of concepts and methods	10
Treatment and mechanism of fecal microbiota transplantation in mice with experimentally induced ulcerative colitis	10
Silencing p53 inhibits interleukin 10-induced activated hepatic stellate cell senescence and fibrotic degradation in vivo	10
Microphysiological systems: What it takes for community adoption	10
Islet cell encapsulation – Application in diabetes treatment	10
COVID-19 global pandemic planning: Performance and electret charge of N95 respirators after recommended decontamination methods	10
COMMD1 upregulation is involved in copper efflux from ischemic hearts	10
Inter-proteomic posttranslational modifications of the SARS-CoV-2 and the host proteins ‒ A new frontier	10
Hyperinflammation, apoptosis, and organ damage	10
Pre-diabetes and COVID-19, could we be missing the silent killer?	10
Ultrasound cavitation enhanced chemotherapy: In vivo research and clinical application	10
YAP activation in melanoma contributes to anoikis resistance and metastasis	10
Ligustilide counteracts carcinogenesis and hepatocellular carcinoma cell-evoked macrophage M2 polarization by regulating yes-associated protein-mediated interleukin-6 secretion	10
Bacteriophages immunomodulate the response of monocytes	10
Influence of exercise training on diabetic kidney disease: A brief physiological approach	10
Relationship between hyperglycemia, waist circumference, and the course of COVID-19: Mortality risk assessment	10
Elevated RUNX1 is a prognostic biomarker for human head and neck squamous cell carcinoma	10
Recent developments in autophagy-targeted therapies in cancer	9
Fetuin-A exerts a protective effect against experimentally induced intestinal ischemia/reperfusion by suppressing autophagic cell death	9
Intranasal administration of mitochondria improves spatial memory in olfactory bulbectomized mice	9
Regulation of 1 and 24 hydroxylation of vitamin D metabolites in the proximal tubule	9
Three-dimensional models of breast cancer–fibroblasts interactions	9
Exploring machine learning for audio-based respiratory condition screening: A concise review of databases, methods, and open issues	9

OCT imaging of rod mitochondrial respiration in vivo	9
Sounding out the hidden data: A concise review of deep learning in photoacoustic imaging	9
Contrast effects of autophagy in the treatment of bladder cancer	9
The neurovascular extracellular matrix in health and disease	9
Histone deacetylases in modulating cardiac disease and their clinical translational and therapeutic implications	9
Telmisartan ameliorates cardiac fibrosis and diastolic function in cardiorenal heart failure with preserved ejection fraction	9
RASL11B gene enhances hyaluronic acid-mediated chondrogenic differentiation in human amniotic mesenchymal stem cells via the activation of Sox9/ERK/smad signals	9
Hydrogen sulfide attenuates diabetic neuropathic pain through NO/cGMP/PKG pathway and μ-opioid receptor	9
Macrophage polarization in hypoxia and ischemia/reperfusion: Insights into the role of energetic metabolism	9
Label-free characterization of collagen fibers in cancerous esophagus tissues using ratiometric nonlinear optical microscopy	9
White matter abnormalities in fetal alcohol spectrum disorders: Focus on axon growth and guidance	9
Cell cycle disturbances in mucopolysaccharidoses: Transcriptomic and experimental studies on cellular models	9
Predictive values of sST2 and IL-33 for heart failure in patients with acute myocardial infarction	9
Developing portable widefield fundus camera for teleophthalmology: Technical challenges and potential solutions	9
Redox treatment ameliorates diabetes mellitus-induced skin flap necrosis via inhibiting apoptosis and promoting neoangiogenesis	9
Delivery of microRNA-21-sponge and pre-microRNA-122 by MS2 virus-like particles to therapeutically target hepatocellular carcinoma cells	9
Antiviral activity of medicinal plant-derived products against SARS-CoV-2	9
Protective effect of exogenous hydrogen sulfide on diaphragm muscle fibrosis in streptozotocin-induced diabetic rats	9
Serum-derived exosomes from neurofibromatosis type 1 congenital tibial pseudarthrosis impaired bone by promoting osteoclastogenesis and inhibiting osteogenesis	8
Three-dimensional segmentation and depth-encoded visualization of choroidal vasculature using swept-source optical coherence tomography	8
Cytosolic protein quality control machinery: Interactions of Hsp70 with a network of co-chaperones and substrates	8
Systemic analysis of the expression levels and prognosis of breast cancer-related cadherins	8
Quantification of biomechanical properties of human corneal scar using acoustic radiation force optical coherence elastography	8
TFPI and FXIII negatively and S100A8/A9 and Cystatin C positively correlate with D-dimer in COVID-19	8
Deep learning prediction of attention-deficit hyperactivity disorder in African Americans by copy number variation	8
A novel variant in DMXL2 gene is associated with autosomal dominant non-syndromic hearing impairment (DFNA71) in a Cameroonian family	8
Histone deacetylase-3: Friend and foe of the brain	8
Impact of spexin on metabolic diseases and inflammation: An updated minireview	8
Potential biomarkers in septic shock besides lactate	8
Shear type and magnitude affect aortic valve endothelial cell morphology, orientation, and differentiation	8
Combining contrast-enhanced ultrasound and blood cell analysis to improve diagnostic accuracy of plasma cell mastitis	8
Store-operated calcium entry: Pivotal roles in renal physiology and pathophysiology	8
Sickle cell vaso-occlusion: The dialectic between red cells and white cells	8
Is sweat a possible route of transmission of SARS-CoV-2?	8
Apigeninidin-enriched Sorghum bicolor (L. Moench) extracts alleviate Aflatoxin B1-induced dysregulation of male rat hypothalamic-reproductive axis	8
Iron overload cardiomyopathy: Using the latest evidence to inform future applications	8
Pathogenesis and brain functional imaging in nocturnal enuresis: A review	8
Epigallocatechin-3-gallate ameliorates renal endoplasmic reticulum stress-mediated inflammation in type 2 diabetic rats	8
Shortened derivatives from native antimicrobial peptide LyeTx I: In vitro and in vivo biological activity assessment	8
Classification of salivary bacteriome in asymptomatic COVID-19 cases based on long-read nanopore sequencing	7
Is COVID-19-associated cytokine storm distinct from non-COVID-19 secondary hemophagocytic lymphohistiocytosis?	7
Protective antioxidative and anti-inflammatory actions of β-caryophyllene against sulfasalazine-induced nephrotoxicity in rat	7
Stem cell-based treatment of kidney diseases	7
Curcumin attenuates vascular calcification via the exosomal miR-92b-3p/KLF4 axis	7
Transcellular routes of blood–brain barrier disruption	7
Analyses of short-chain fatty acids and exhaled breath volatiles in dietary intervention trials for metabolic diseases	7
Identification of histone acetylation in a murine model of allergic asthma by proteomic analysis	7
Regulation of lymphangiogenesis by extracellular vesicles in cancer metastasis	7
The role of calcium-sensing receptor signaling in regulating transepithelial calcium transport	7
COVID-19 global pandemic planning: Presence of SARS-CoV-2 fomites in a university hospital setting	7
Blockade of OGFr delays the onset and reduces the severity of diabetic ocular surface complications	7
Animal models of regenerative medicine for biological treatment approaches of degenerative disc diseases	7
Management of altered metabolic activity in Drosophila model of Huntington’s disease by curcumin	7
A novel microRNA-based signature predicts prognosis among nasopharyngeal cancer patients	7
Recent insights into atherosclerotic plaque cell autophagy	7
Electronic nicotine delivery system-induced alterations in oral health via saliva assessment	7
Inhibition of phospholipases suppresses progression of psoriasis through modulation of inflammation	7
Inhibition of protein kinase C beta phosphorylation activates nuclear factor-kappa B and improves postischemic recovery in type 1 diabetes	7
Altered gene expression in glycolysis–cholesterol synthesis axis correlates with outcome of triple-negative breast cancer	7
Atherosclerotic lesion-specific copper delivery suppresses atherosclerosis in high-cholesterol-fed rabbits	7
At the dawn of the transcriptomic medicine	7
Pancreatic acinar cells utilize tyrosine to synthesize L-dihydroxyphenylalanine	6
Nomograms-based prediction of overall and cancer-specific survivals for patients with chromophobe renal cell carcinoma	6
Microbial extracellular RNAs and their roles in human diseases	6
Increased alpha and beta cell mass during mouse pregnancy is not dependent on transdifferentiation	6
Preclinical and clinical studies of bintrafusp alfa, a novel bifunctional anti-PD-L1/TGFβRII agent: Current status	6
Analysis of epigenetic aging in vivo and in vitro: Factors controlling the speed and direction	6
Screening a chemically defined extracellular matrix mimetic substrate library to identify substrates that enhance substrate-mediated transfection	6
Galangin: A metabolite that suppresses anti-neoplastic activities through modulation of oncogenic targets	6
Particulate matter inhalation and the exacerbation of cardiopulmonary toxicity due to metabolic disease	6
Cytoplasmic mislocalization and mitochondrial colocalization of TDP-43 are common features between normal aged and young mice	6
Fluid shear stress modulates endothelial inflammation by targeting LIMS2	6
Retinoid analogs and polyphenols as potential therapeutics for age-related macular degeneration	6
Genetic interaction between two VNTRs in the MAOA gene is associated with the nicotine dependence	6
Overexpression of p53 accelerates puberty in high-fat diet–fed mice through Lin28/let-7 system	6
Overexpression of HOXA10 promotes the growth and metastasis of nasopharyngeal carcinoma	6
COVID-19 and diabetes: What do we know so far?	6
Construction of enzalutamide-resistant cell model of prostate cancer and preliminary screening of potential drug-resistant genes	6
The contribution of the immune system to genitourinary fibrosis	6
WGCNA analysis of the subcutaneous fat transcriptome in a novel tree shrew model	6
Respiratory mechanics evaluation of mice submitted to intravenous methacholine: Bolus vs. continuous infusion	6
Zoledronic acid modulates osteoclast apoptosis through activation of the NF-κB signaling pathway in ovariectomized rats	6
Role of age and neuroinflammation in the mechanism of cognitive deficits in sickle cell disease	6
Stopping the COVID-19 pandemic in dental offices: A review of SARS-CoV-2 transmission and cross-infection prevention	6
Wogonin, as a potent anticancer compound: From chemistry to cellular interactions	6
MiR-296-5p ameliorates deep venous thrombosis by inactivating S100A4	6
Dysregulation of the OGF–OGFr pathway correlates with elevated serum OGF and ocular surface complications in the diabetic rat	6
Lnc-ATG9B-4 aggravates progress of hepatocellular carcinoma through cell proliferation and migration by upregulating CDK5	6
Mechanisms of disease-associated SINE-VNTR-Alus	6
Intermittent hypoxia promotes the recovery of motor function in rats with cerebral ischemia by regulating mitochondrial function	6
Comprehensive analysis of INHBA: A biomarker for anti-TGFβ treatment in head and neck cancer	5
Whole exome sequencing identifies rare coding variants in novel human-mouse ortholog genes in African individuals diagnosed with non-syndromic hearing impairment	5
Protective effects of molecular hydrogen on lung injury from lung transplantation	5
Identification of SARS-CoV-2 on the ocular surface in a cohort of COVID-19 patients from Brazil	5
The clinical phenotype of bronchiectasis and its clinical guiding implications	5