Experimental Biology and Medicine

Article	Citations
Influence of glutamate and GABA transport on brain excitatory/inhibitory balance	102
Cancer and stem cells	65
Going with the grain: Fiber, cognition, and the microbiota-gut-brain-axis	55
Detection of severe acute respiratory syndrome coronavirus 2 and influenza viruses based on CRISPR-Cas12a	55
Nitric oxide modulation in neuroinflammation and the role of mesenchymal stem cells	50
A mini-review on the effects of COVID-19 on younger individuals	40
Breast cancer in sub-Saharan Africa: The current state and uncertain future	39
Nicorandil inhibits TLR4/MyD88/NF-κB/NLRP3 signaling pathway to reduce pyroptosis in rats with myocardial infarction	39
Dysregulation of brain dopamine systems in major depressive disorder	38
CD9, a tetraspanin target for cancer therapy?	36
Role of sex hormones in lung cancer	32
The effect of ultrasound cavitation on endothelial cells	29
Emerging technologies and their impact on regulatory science	29
Imaging and artificial intelligence for progression of age-related macular degeneration	26
The multifunctionality of expression systems in Bacillus subtilis: Emerging devices for the production of recombinant proteins	26
Overcoming physiological barriers by nanoparticles for intravenous drug delivery to the lymph nodes	26
Transcriptomic profiles in Parkinson’s disease	25
Silicon: A neglected micronutrient essential for bone health	24
Photoacoustic imaging systems based on clinical ultrasound platform	24
Oral microbiota in human health and disease: A perspective	24
Role of myokines and osteokines in cancer cachexia	24
The “ideal protein” concept is not ideal in animal nutrition	24
Resveratrol alleviates alveolar epithelial cell injury induced by hyperoxia by reducing apoptosis and mitochondrial dysfunction	23
Protease-activated receptor 1 as a potential therapeutic target for COVID-19	22
12 Survival-related differentially expressed genes based on the TARGET-osteosarcoma database	22

Bacterial microbiota in upper respiratory tract of COVID-19 and influenza patients	22
Machine learning in optical coherence tomography angiography	21
Metformin and retinal diseases in preclinical and clinical studies: Insights and review of literature	21
Therapeutically leveraging GABAA receptors in cancer	20
CCNB1 promotes the development of hepatocellular carcinoma by mediating DNA replication in the cell cycle	20
Innovative approaches for treatment of osteosarcoma	19
Secretory phospholipase A2 in SARS-CoV-2 infection and multisystem inflammatory syndrome in children (MIS-C)	19
Regulation of Th1/Th2 and Th17/Treg by pDC/mDC imbalance in primary immune thrombocytopenia	19
Carbon “quantum” dots for bioapplications	19
SARS-CoV-2 variants: A double-edged sword?	18
Lipocalin-2, S100A8/A9, and cystatin C: Potential predictive biomarkers of cardiovascular complications in COVID-19	18
Whole-genome sequencing as a first-tier diagnostic framework for rare genetic diseases	18
A GM1 gangliosidosis mutant mouse model exhibits activated microglia and disturbed autophagy	18
Genomic analysis of SARS-CoV-2 reveals local viral evolution in Ghana	18
Adipose-derived stem cells in ovarian cancer progression, metastasis, and chemoresistance	18
Importance of extracellular vesicles in hypertension	17
Biological evidence to define a vitamin A deficiency cutoff using total liver vitamin A reserves	17
Interpretation of anatomic correlates of outer retinal bands in optical coherence tomography	17
Rapid and ultrasensitive detection of circulating human papillomavirus E7 cell-free DNA as a cervical cancer biomarker	17
FOXM1 activates JAK1/STAT3 pathway in human osteoarthritis cartilage cell inflammatory reaction	17
The use of DNA methylation clock in aging research	17
WNT signaling in atrial fibrillation	17
Single-cell RNA sequencing reveals differential expression of EGFL7 and VEGF in giant-cell tumor of bone and osteosarcoma	17
Sickle cell disease as an accelerated aging syndrome	16
The molecular mechanisms of acetaminophen-induced hepatotoxicity and its potential therapeutic targets	16
Hypoxic colorectal cancer-secreted exosomes deliver miR-210-3p to normoxic tumor cells to elicit a protumoral effect	16
Ligustilide counteracts carcinogenesis and hepatocellular carcinoma cell-evoked macrophage M2 polarization by regulating yes-associated protein-mediated interleukin-6 secretion	16
KDM1A and KDM3A promote tumor growth by upregulating cell cycle-associated genes in pancreatic cancer	15
Variable number tandem repeats – Their emerging role in sickness and health	15
Survival stratification for colorectal cancer via multi-omics integration using an autoencoder-based model	15
Effect of vitamin D3 supplementation on hepatic lipid dysregulation associated with autophagy regulatory AMPK/Akt-mTOR signaling in type 2 diabetic mice	15
YAP activation in melanoma contributes to anoikis resistance and metastasis	15
Mechanisms of disease-associated SINE-VNTR-Alus	15
Mitophagy promotes the stemness of bone marrow-derived mesenchymal stem cells	15
Circulating LIPCAR is a potential biomarker of heart failure in patients post-acute myocardial infarction	15
Intranasal administration of mitochondria improves spatial memory in olfactory bulbectomized mice	15
Microphysiological systems: What it takes for community adoption	15
Long non-coding RNA IGF2-AS represses breast cancer tumorigenesis by epigenetically regulating IGF2	15
Arbutin ameliorates glucocorticoid-induced osteoporosis through activating autophagy in osteoblasts	15
Functional intrinsic optical signal imaging for objective optoretinography of human photoreceptors	15
E2F3 drives the epithelial-to-mesenchymal transition, cell invasion, and metastasis in breast cancer	14
Regulation of 1 and 24 hydroxylation of vitamin D metabolites in the proximal tubule	14
Identification of potential lipid biomarkers for active pulmonary tuberculosis using ultra-high-performance liquid chromatography-tandem mass spectrometry	14
Exploring machine learning for audio-based respiratory condition screening: A concise review of databases, methods, and open issues	14
Irisin induces white adipose tissue browning in mice as assessed by magnetic resonance imaging	14
Osteopontin as a biomarker for COVID-19 severity and multisystem inflammatory syndrome in children: A pilot study	14
Telmisartan ameliorates cardiac fibrosis and diastolic function in cardiorenal heart failure with preserved ejection fraction	14
Simultaneous visible light optical coherence tomography and near infrared OCT angiography in retinal pathologies: A case study	14
Developing portable widefield fundus camera for teleophthalmology: Technical challenges and potential solutions	14
Iron overload cardiomyopathy: Using the latest evidence to inform future applications	14

Store-operated calcium entry: Pivotal roles in renal physiology and pathophysiology	14
Minireview: Insights into anti-interferon-γ autoantibodies	14
Clinical applications of 3D normal and breast cancer organoids: A review of concepts and methods	14
Convalescent serum-derived exosomes: Attractive niche as COVID-19 diagnostic tool and vehicle for mRNA delivery	14
Antiviral activity of medicinal plant-derived products against SARS-CoV-2	14
Hyperinflammation after anti-SARS-CoV-2 mRNA/DNA vaccines successfully treated with anakinra: Case series and literature review	13
Delivery of microRNA-21-sponge and pre-microRNA-122 by MS2 virus-like particles to therapeutically target hepatocellular carcinoma cells	13
Hyperinflammation, apoptosis, and organ damage	13
Atherosclerotic lesion-specific copper delivery suppresses atherosclerosis in high-cholesterol-fed rabbits	13
Pulmonary gene delivery—Realities and possibilities	13
The antifibrotic role of natural killer cells in liver fibrosis	13
Management of altered metabolic activity in Drosophila model of Huntington’s disease by curcumin	13
Inflammatory response and matrix metalloproteinases in chronic kidney failure: Modulation by adropin and spexin	13
Inhibitory effect of hydnocarpin D on T-cell acute lymphoblastic leukemia via induction of autophagy-dependent ferroptosis	13
OCT imaging of rod mitochondrial respiration in vivo	12
Epigallocatechin-3-gallate attenuates myocardial fibrosis in diabetic rats by activating autophagy	12
Treatment and mechanism of fecal microbiota transplantation in mice with experimentally induced ulcerative colitis	12
Relationship between hyperglycemia, waist circumference, and the course of COVID-19: Mortality risk assessment	12
Wogonin, as a potent anticancer compound: From chemistry to cellular interactions	12
Pre-diabetes and COVID-19, could we be missing the silent killer?	12
Elevated RUNX1 is a prognostic biomarker for human head and neck squamous cell carcinoma	12
Sounding out the hidden data: A concise review of deep learning in photoacoustic imaging	11
Fetuin-A exerts a protective effect against experimentally induced intestinal ischemia/reperfusion by suppressing autophagic cell death	11
TFPI and FXIII negatively and S100A8/A9 and Cystatin C positively correlate with D-dimer in COVID-19	11
Sickle cell vaso-occlusion: The dialectic between red cells and white cells	11
Impact of spexin on metabolic diseases and inflammation: An updated minireview	11
Islet cell encapsulation – Application in diabetes treatment	11
Bacteriophages immunomodulate the response of monocytes	11
Macrophage polarization in hypoxia and ischemia/reperfusion: Insights into the role of energetic metabolism	11
Deep learning prediction of attention-deficit hyperactivity disorder in African Americans by copy number variation	11
Animal models of regenerative medicine for biological treatment approaches of degenerative disc diseases	11
COVID-19 global pandemic planning: Performance and electret charge of N95 respirators after recommended decontamination methods	11
Redox treatment ameliorates diabetes mellitus-induced skin flap necrosis via inhibiting apoptosis and promoting neoangiogenesis	11
Treatment of osteoporosis with a modified zeolite shows beneficial effects in an osteoporotic rat model and a human clinical trial	11
Increased alpha and beta cell mass during mouse pregnancy is not dependent on transdifferentiation	11
Apigeninidin-enriched Sorghum bicolor (L. Moench) extracts alleviate Aflatoxin B1-induced dysregulation of male rat hypothalamic-reproductive axis	11
Predictive values of sST2 and IL-33 for heart failure in patients with acute myocardial infarction	11
Emerging role of N6-methyladenosine RNA methylation in lung diseases	11
Indigenous Nigeria medicinal herbal remedies: A potential source for therapeutic against rheumatoid arthritis	11
Modern approaches on stem cells and scaffolding technology for osteogenic differentiation and regeneration	11
Protective antioxidative and anti-inflammatory actions of β-caryophyllene against sulfasalazine-induced nephrotoxicity in rat	10
Tumor cell anabolism and host tissue catabolism-energetic inefficiency during cancer cachexia	10
Recent insights into atherosclerotic plaque cell autophagy	10
COMMD1 upregulation is involved in copper efflux from ischemic hearts	10
Inter-proteomic posttranslational modifications of the SARS-CoV-2 and the host proteins ‒ A new frontier	10
Galangin: A metabolite that suppresses anti-neoplastic activities through modulation of oncogenic targets	10
Transcellular routes of blood–brain barrier disruption	10
hsa-miR-607, lncRNA TUG1 and hsa_circ_0071106 can be combined as biomarkers in type 2 diabetes mellitus	10
Recent developments in autophagy-targeted therapies in cancer	10
Is COVID-19-associated cytokine storm distinct from non-COVID-19 secondary hemophagocytic lymphohistiocytosis?	10
Analyses of short-chain fatty acids and exhaled breath volatiles in dietary intervention trials for metabolic diseases	10
Systemic analysis of the expression levels and prognosis of breast cancer-related cadherins	10
Metabolomic profiling of anaerobic and aerobic energy metabolic pathways in chronic obstructive pulmonary disease	10
The neurovascular extracellular matrix in health and disease	10
Combining contrast-enhanced ultrasound and blood cell analysis to improve diagnostic accuracy of plasma cell mastitis	9
Three-dimensional segmentation and depth-encoded visualization of choroidal vasculature using swept-source optical coherence tomography	9
Inhibition of phospholipases suppresses progression of psoriasis through modulation of inflammation	9
Blockade of OGFr delays the onset and reduces the severity of diabetic ocular surface complications	9
Zoledronic acid modulates osteoclast apoptosis through activation of the NF-κB signaling pathway in ovariectomized rats	9
White matter abnormalities in fetal alcohol spectrum disorders: Focus on axon growth and guidance	9
Cell cycle disturbances in mucopolysaccharidoses: Transcriptomic and experimental studies on cellular models	9
Preclinical and clinical studies of bintrafusp alfa, a novel bifunctional anti-PD-L1/TGFβRII agent: Current status	9
COVID-19 and diabetes: What do we know so far?	9
Isoorientin ameliorates OVA-induced asthma in a murine model of asthma	9
Pathogenesis and brain functional imaging in nocturnal enuresis: A review	9
Identification of histone acetylation in a murine model of allergic asthma by proteomic analysis	9
Shear type and magnitude affect aortic valve endothelial cell morphology, orientation, and differentiation	9
Therapeutic potentials of stem cell–derived exosomes in cardiovascular diseases	9
The role of calcium-sensing receptor signaling in regulating transepithelial calcium transport	9
Cytosolic protein quality control machinery: Interactions of Hsp70 with a network of co-chaperones and substrates	9
Bile acids as carcinogens in the colon and at other sites in the gastrointestinal system	9
Ethical and regulatory oversight of clinical research: The role of the Institutional Review Board	9
Cellular senescence and the blood–brain barrier: Implications for aging and age-related diseases	9
Review of machine learning and deep learning models for toxicity prediction	8
Curcumin attenuates vascular calcification via the exosomal miR-92b-3p/KLF4 axis	8
Particulate matter inhalation and the exacerbation of cardiopulmonary toxicity due to metabolic disease	8
Epigallocatechin-3-gallate ameliorates renal endoplasmic reticulum stress-mediated inflammation in type 2 diabetic rats	8
Shortened derivatives from native antimicrobial peptide LyeTx I: In vitro and in vivo biological activity assessment	8
A novel variant in DMXL2 gene is associated with autosomal dominant non-syndromic hearing impairment (DFNA71) in a Cameroonian family	8
Altered gene expression in glycolysis–cholesterol synthesis axis correlates with outcome of triple-negative breast cancer	8

Quantifying the progression of non-alcoholic fatty liver disease in human biomimetic liver microphysiology systems with fluorescent protein biosensors	8
A new insight of immunosuppressive microenvironment in osteosarcoma lung metastasis	8
Quantification of biomechanical properties of human corneal scar using acoustic radiation force optical coherence elastography	8
Quercetin suppresses ovariectomy-induced osteoporosis in rat mandibles by regulating autophagy and the NLRP3 pathway	8
Exploring epigenetic and microRNA approaches for γ-globin gene regulation	8
Synthesis of glycine from 4-hydroxyproline in tissues of neonatal pigs	8
Classification of salivary bacteriome in asymptomatic COVID-19 cases based on long-read nanopore sequencing	8
MiR-296-5p ameliorates deep venous thrombosis by inactivating S100A4	8
Eugenol alleviates neuronal damage via inhibiting inflammatory process against pilocarpine-induced status epilepticus	7
Smad7 attenuates TGF-β-mediated aging-related hypofunction of submandibular glands	7
Overexpression of HOXA10 promotes the growth and metastasis of nasopharyngeal carcinoma	7
COVID-19 global pandemic planning: Presence of SARS-CoV-2 fomites in a university hospital setting	7
MiR-22-3p and miR-29a-3p synergistically inhibit hepatic stellate cell activation by targeting AKT3	7
GDF15plays a critical role in insulin secretion in INS-1 cells and human pancreatic islets	7
Pancreatic acinar cells utilize tyrosine to synthesize L-dihydroxyphenylalanine	7
Implications of fibrotic extracellular matrix in diabetic retinopathy	7
Stopping the COVID-19 pandemic in dental offices: A review of SARS-CoV-2 transmission and cross-infection prevention	7
Protective effects of molecular hydrogen on lung injury from lung transplantation	7
Natural antioxidants attenuate mycolactone toxicity to RAW 264.7 macrophages	7
Weakly supervised learning and interpretability for endometrial whole slide image diagnosis	7
Overall and cancer-specific survival in patients with breast Paget disease: A population-based study	7
Intermittent hypoxia promotes the recovery of motor function in rats with cerebral ischemia by regulating mitochondrial function	7
Recent advances in nanotechnology-enabled biosensors for detection of exosomes as new cancer liquid biopsy	7
Regulation of lymphangiogenesis by extracellular vesicles in cancer metastasis	7
Machine learning and deep learning for brain tumor MRI image segmentation	7
l-Arginine supplementation regulates energy-substrate metabolism in skeletal muscle and adipose tissue of diet-induced obese rats	7
Assessment of the influence on left ventricle by potassium oxonate and hypoxanthine–induced chronic hyperuricemia	7
Specialized pro-resolution mediators in the bladder: Receptor expression and recovery of bladder function from cystitis	7
Non-thermal plasma application enhances the recovery of transected sciatic nerves in rats	7
Ultrasound in ocular oncology: Technical advances, clinical applications, and limitations	7
Single-cell RNA-seq identification of four differentially expressed survival-related genes by a TARGET: Osteosarcoma database analysis	7
JAK inhibitors for the treatment of VEXAS syndrome	7
Emerging roles for lymphatics in acute kidney injury: Beneficial or maleficent?	7
Role of long interspersed nuclear element-1 in the regulation of chromatin landscapes and genome dynamics	7
ISGylation is increased in the peripheral blood mononuclear cells derived from symptomatic COVID-19 patients	6
Impacts of microgravity on amino acid metabolism during spaceflight	6
Integrating photoacoustic microscopy with other imaging technologies for multimodal imaging	6
Modeling adaptive drug resistance of colorectal cancer and therapeutic interventions with tumor spheroids	6
Tastin promotes non-small-cell lung cancer progression through the ErbB4, PI3K/AKT, and ERK1/2 pathways	6
The contribution of the immune system to genitourinary fibrosis	6
Prenatal indole-3-carbinol administration activates aryl hydrocarbon receptor-responsive genes and attenuates lung injury in a bronchopulmonary dysplasia model	6
Proteinase 3 contributes to endothelial dysfunction in an experimental model of sepsis	6
Convergence of human pluripotent stem cell, organoid, and genome editing technologies	6
Inhibition of glioma by adenovirus KGHV500 encoding anti-p21Ras scFv and carried by cytokine-induced killer cells	6
In vitro comparative evaluation of Tamarix gallica extracts for antioxidant and antidiabetic activity	6
Human-derived osteoblast-like cells and pericyte-like cells induce distinct metastatic phenotypes in primary breast cancer cells	6
Manipulation of genes could inhibit SARS-CoV-2 infection that causes COVID-19 pandemics	6
Effects of hydrogen as adjuvant treatment for unstable angina	6
Qualification of translational safety biomarkers	6
Construction of enzalutamide-resistant cell model of prostate cancer and preliminary screening of potential drug-resistant genes	6
The clinical phenotype of bronchiectasis and its clinical guiding implications	6
Cyclin D1b induces changes in the macrophage phenotype resulting in promotion of tumor metastasis	6
Bee venom ameliorates cardiac dysfunction in diabetic hyperlipidemic rats	6
Association of plasma acylcarnitines with insulin sensitivity, insulin secretion, and prediabetes in a biracial cohort	6
Hypothermia preconditioning improves cardiac contractility after cardiopulmonary resuscitation through AMPK-activated mitophagy	6
Renal cystic disease in tuberous sclerosis complex	6
A comprehensive overview of PPM1A: From structure to disease	6
Diagnostic applications of microsphere-based flow cytometry: A review	6
CTRP3 protects against uric acid-induced endothelial injury by inhibiting inflammation and oxidase stress in rats	6
Analyses of lung cancer-derived volatiles in exhaled breath and in vitro models	6
PGM3 regulates beta-catenin activity to promote colorectal cancer cell progression	6
Longitudinal intronic RNA-Seq analysis of Parkinson’s disease patients reveals disease-specific nascent transcription	6
Characterizing disease progression of nonalcoholic steatohepatitis in Leptin-deficient rats by integrated transcriptome analysis	6
Nuclear translocation of β-catenin induced by E-cadherin endocytosis causes recurrent erosion of diabetic cornea	6
Association of genetic variants rs641153 (CFB), rs2230199 (C3), and rs1410996 (CFH) with age-related macular degeneration in a Brazilian population	6
Nitric oxide and sickle cell disease—Is there a painful connection?	6
Identification of SARS-CoV-2 on the ocular surface in a cohort of COVID-19 patients from Brazil	6
Epstein-Barr virus microRNA BART10-3p promotes dedifferentiation and proliferation of nasopharyngeal carcinoma by targeting ALK7	6
Store-operated Ca2+ channel signaling: Novel mechanism for podocyte injury in kidney disease	6
Succinate dehydrogenase complex subunit C: Role in cellular physiology and disease	6
Hypoxia–CXCL6 axis affects arteriolar niche remodeling in acute myeloid leukemia	6
Mitotic kinases as drivers of the epithelial-to-mesenchymal transition and as therapeutic targets against breast cancers	6
Is graphene the rock upon which new era continuous glucose monitors could be built?	6
Delayed tezampanel and caramiphen treatment but not midazolam protects against long-term neuropathology after soman exposure	6
Deep learning for artery–vein classification in optical coherence tomography angiography	6
Nomograms-based prediction of overall and cancer-specific survivals for patients with chromophobe renal cell carcinoma	6
Alginate microfibers as therapeutic delivery scaffolds and tissue mimics	6
Melatonin pretreatment modulates anti-inflammatory, antioxidant, YKL-40, and matrix metalloproteinases in endotoxemic rat lung tissue	6
Cytokinesis regulators as potential diagnostic and therapeutic biomarkers for human hepatocellular carcinoma	6
Indoxyl sulfate impairs in vitro erythropoiesis by triggering apoptosis and senescence	6
Comparative study of optical coherence tomography angiography algorithms for rodent retinal imaging	6
ONECUT2 which is targeted by hsa-miR-15a-5p enhances stemness maintenance of gastric cancer stem cells	6
Asthma, atopy, and exercise: Sex differences in exercise-induced bronchoconstriction	6
Comprehensive analysis of INHBA: A biomarker for anti-TGFβ treatment in head and neck cancer	6
Ginkgolide B promotes oligodendrocyte precursor cell differentiation and survival via Akt/CREB/bcl-2 signaling pathway after white matter lesion	5
Regenerative and stem cell-based techniques for facial rejuvenation	5
Fatty acid ethyl esters in meconium: A biomarker of fetal alcohol exposure and effect	5
Mutant U2AF1-induced differential alternative splicing causes an oxidative stress in bone marrow stromal cells	5
Barley microgreen incorporation in diet-controlled diabetes and counteracted aflatoxicosis in rats	5
Identification in synovial fluid of a new potential pathogenic player in arthropathies	5
Engineering microenvironments for manufacturing therapeutic cells	5
miR-31 promotes neural stem cell proliferation and restores motor function after spinal cord injury	5
WISP1 aggravates cell metastatic potential by abrogating TGF-β-Smad2/3-dependent epithelial-to-mesenchymal transition in laryngeal squamous cell carcinoma	5
Revisiting the role of lysophosphatidic acid in stem cell biology	5
Stattic alleviates pulmonary fibrosis in a mouse model of rheumatoid arthritis–relevant interstitial lung disease	5