Experimental Biology and Medicine

Article	Citations
Three-dimensional segmentation and depth-encoded visualization of choroidal vasculature using swept-source optical coherence tomography	61
Dual detection of COVID-19 antigens and antibodies using nanoscale fluorescent plasmonic substrates	52
Paraoxonase 1 rs662 polymorphism, its related variables, and COVID-19 intensity: Considering gender and post-COVID complications	48
Circulating exosomal microRNA-4497 as a potential biomarker for metastasis and prognosis in non-small-cell lung cancer	43
Roles of IL-33 in the Pathogenesis of Cardiac Disorders	40
Participation of ASK-1 in the cardiomyocyte-protective role of mechanical ventilation in a rat model of myocardial infarction	34
Wogonin, as a potent anticancer compound: From chemistry to cellular interactions	34
Green synthesized silver nanoparticles for the treatment of diabetes and the related complications of hyperlipidemia and oxidative stress in diabetic rats	33
Bioinformatics analysis of the genes associated with co-occurrence of heart failure and lung cancer	33
Regulation of lymphangiogenesis by extracellular vesicles in cancer metastasis	30
Classification of salivary bacteriome in asymptomatic COVID-19 cases based on long-read nanopore sequencing	30
Comprehensive analysis of dysregulated genes associated with atherosclerotic plaque destabilization	30
The continuing evolution of barcode applications: Functional toxicology to cell lineage	27
Mild hypobaric hypoxia influences splenic proliferation during the later phase of stress erythropoiesis	26
The influence of multidisciplinary team clinic on the prognosis of patients with chronic kidney disease	25
Indoxyl sulfate impairs in vitro erythropoiesis by triggering apoptosis and senescence	25
Autotaxin–lysophosphatidic acid receptor 5 axis evokes endothelial dysfunction via reactive oxygen species signaling	24
Shear type and magnitude affect aortic valve endothelial cell morphology, orientation, and differentiation	24
S-allylmercapto-N-acetylcysteine protects bone cells from oxidation and improves femur microarchitecture in healthy and diabetic mice	23
Serum homocysteine is a valuable marker for predicting aggravation of infection in intestinal obstruction patients	23
Data science in drug discovery safety: Challenges and opportunities	22
Combining tissue clearing and Fluoro-Jade C labeling for neurotoxicity assessments	21
A primordial target: Mitochondria mediate both primary and collateral anesthetic effects of volatile anesthetics	21
Beclin1- and Atg13-dependent autophagy activation and morroniside have synergistic effect on osteoblastogenesis	21
Gentiopicroside alleviates acute myocardial infarction injury in rats by disrupting Nrf2/NLRP3 signaling	21

Dysregulation of multiple signaling pathways: A possible cause of cerebral palsy	20
CTRP3 protects against uric acid-induced endothelial injury by inhibiting inflammation and oxidase stress in rats	20
Interleukin-10 regulates starvation-induced autophagy through the STAT3-mTOR-p70s6k axis in hepatic stellate cells	20
In-ovo imaging using ostrich eggs: Biomagnetism for detection of cardiac signals and embryonal motion	20
The role of IL-33/ST2 signaling in the tumor microenvironment and Treg immunotherapy	20
Statistical considerations for outcomes in clinical research: A review of common data types and methodology	20
Assessments of tumor mutational burden estimation by targeted panel sequencing: A comprehensive simulation analysis	19
Ubiquinol-cytochrome c reductase core protein 1 contributes to cardiac tolerance to acute exhaustive exercise	19
Thermo- and pH-sensitive nanoparticles of poly (N-isopropylacrylamide-decenoic acid-1-vinylimidazole) for ultrasound switchable fluorescence imaging	19
Phenotyping in clinical text with unsupervised numerical reasoning for patient stratification	19
Evaluation of the mechanisms of heme-induced tissue factor activation: Contribution of innate immune pathways	19
Inferences of carboplatin response-related signature by integrating multiomics data in ovarian serous cystadenocarcinoma	19
Retraction Notice	19
Fluoride induces osteoblast autophagy by inhibiting the PI3K/AKT/mTOR signaling pathway in vivo and in vitro	18
Arbovirus surveillance in mosquitoes: Historical methods, emerging technologies, and challenges ahead	18
Structural and molecular biology of Sabiá virus	18
Classifying and evaluating fetuses with multicystic dysplastic kidney in etiologic studies	18
Exogenous surfactant reduces inflammation and redox imbalance in rats under prone or supine mechanical ventilation	18
OCT imaging of rod mitochondrial respiration in vivo	17
Gene expression profile suggests different mechanisms underlying sporadic and familial mesial temporal lobe epilepsy	17
Macrophage polarization in hypoxia and ischemia/reperfusion: Insights into the role of energetic metabolism	17
Explainable hierarchical clustering for patient subtyping and risk prediction	17
Tastin promotes non-small-cell lung cancer progression through the ErbB4, PI3K/AKT, and ERK1/2 pathways	17
TBX1 regulates myogenic differentiation by activating the TGFβ-Smad2/3 pathway in myoblasts	17
Corrigendum	16
A novel fluorescent traceable carbon quantum dots with selective antibacterial activity against Porphyromonas gingivalis	16
Rhubarb extract rebuilding the mucus homeostasis and regulating mucin-associated flora to relieve constipation	16
Effect of smoking on the redox status of knee osteoarthritis: A preliminary study	16
Interspecies chimeras as a platform for exogenic organ production and transplantation	16
Expression of cytoskeleton-associated protein 4 is associated with poor prognosis and metastasis in nasopharyngeal carcinoma	16
Dapagliflozin-entresto protected kidney from renal hypertension via downregulating cell-stress signaling and upregulating SIRT1/PGC-1α/Mfn2-medicated mitochondrial homeostasis	16
Hydroxytyrosol produced by engineered Escherichia coli strains activates Nrf2/HO-1 pathway: An in vitro and in vivo study	16
Manipulation of unfolded protein response by zoonotic vaccinia virus strains Guarani P1 and Passatempo	16
Review on ultrasound-guided photoacoustic imaging for complementary analyses of biological systems in vivo	16
Maternal serum-derived exosomal lactoferrin as a marker in detecting and predicting ventricular septal defect in fetuses	15
The inducible prostaglandin E synthase (mPGES-1) in neuroinflammatory disorders	15
LOXL2 reduces 5-FU sensitivity through the Hedgehog/BCL2 signaling pathway in colorectal cancer	15
The contribution of the immune system to genitourinary fibrosis	15
Artificial neural network–based diagnostic models for lung cancer combining conventional indicators with tumor markers	15
GDF15plays a critical role in insulin secretion in INS-1 cells and human pancreatic islets	15
Mechanisms of disease-associated SINE-VNTR-Alus	14
Alpha-linolenic acid enhances the facilitation of GABAergic neurotransmission in the BLA and CA1	14
Visceral fat sympathectomy ameliorates systemic and local stress response related to chronic sleep restriction	14
Repurposing medications for treatment of age-related macular degeneration: Insights from novel approaches to data mining	14
JAK inhibitors for the treatment of VEXAS syndrome	14
Soluble form of suppression of tumorigenicity-2 predicts clinical stability of inpatients with community-acquired pneumonia	14
Plasma Galectin-3 and H-FABP correlate with poor physical performance in patients with congestive heart failure	14
Synthesis of glycine from 4-hydroxyproline in tissues of neonatal pigs	14
The dengue virus 4 component of NIAID’s tetravalent TV003 vaccine drives its innate immune signature	14
Metformin inhibits mitochondrial dysfunction and apoptosis in cardiomyocytes induced by high glucose via upregulating AMPK activity	14

Epstein-Barr virus genotype-1 and Mediterranean + strain in gastric cancer biopsies of Ghanaian patients	13
Deep learning diagnostic performance and visual insights in differentiating benign and malignant thyroid nodules on ultrasound images	13
COVID-19 active case findings based on self-collected saliva samples with CRISPR-Cas12a detection	13
Seasonal variation and disease distribution of cytophagocytic mononuclear cells in synovial fluid: A medical record study	13
Methyl mercury triggers endothelial leukocyte adhesion and increases expression of cell adhesion molecules and chemokines	13
An increase in polyadenylation of histone isoforms, Hist1h2ah and Hist2h3c2, is governed by 3′-UTR in de-differentiated and undifferentiated hepatocyte	13
Revolutionized virome research using systems microbiology approaches	12
Analyses of lung cancer-derived volatiles in exhaled breath and in vitro models	12
Clinicopathological significance and underlying molecular mechanism of downregulation of basonuclin 1 expression in ovarian carcinoma	12
Applied artificial intelligence in healthcare: Listening to the winds of change in a post-COVID-19 world	12
Respiratory viral infection and resolution of inflammation: Roles for specialized pro-resolving mediators	12
Telmisartan ameliorates cardiac fibrosis and diastolic function in cardiorenal heart failure with preserved ejection fraction	12
RxBERT: Enhancing drug labeling text mining and analysis with AI language modeling	12
How S100B crosses brain barriers and why it is considered a peripheral marker of brain injury	11
Elevated SARS-CoV-2 in peripheral blood and increased COVID-19 severity in American Indians/Alaska Natives	11
Apelin-13 prevents the effects of oxygen–glucose deprivation/reperfusion on bEnd.3 cells by inhibiting AKT–mTOR signaling	11
Comparative transcriptome analysis of endothelial progenitor cells of HbSS patients with and without proliferative retinopathy	11
Therapeutic effects of kartogenin on temporomandibular joint injury by activating the TGF-β/SMAD pathway in rats	11
Identification of SARS-CoV-2 on the ocular surface in a cohort of COVID-19 patients from Brazil	11
A quantum-based oversampling method for classification of highly imbalanced and overlapped data	11
Aedes-borne orthoflavivirus infections in neotropical primates – Ecology, susceptibility, and pathogenesis	11
Allele-specific silencing by RNAi of R92Q and R173W mutations in cardiac troponin T	11
Osteopontin as a biomarker for COVID-19 severity and multisystem inflammatory syndrome in children: A pilot study	11
The β-catenin/CBP signaling axis participates in sepsis-induced inflammatory lung injury	11
Identifying a cervical cancer survival signature based on mRNA expression and genome-wide copy number variations	10
Changes in gene expression and neuroinflammation in the hippocampus of rats with poststroke cognitive impairment	10
Proteomics analysis of carotid body tumor revealed potential mechanisms and molecular differences among Shamblin classifications	10
Nucleated red blood cells participate in myocardial regeneration in the toad Bufo Gargarizan Gargarizan	10
Focused ultrasound stimulation on meibomian glands for the treatment of evaporative dry eye	10
ONECUT2 which is targeted by hsa-miR-15a-5p enhances stemness maintenance of gastric cancer stem cells	10
Eugenol alleviates neuronal damage via inhibiting inflammatory process against pilocarpine-induced status epilepticus	10
Resistin stimulates PC-3 prostate cancer cell growth through stimulation of SOCS3 and SOCS5 genes	10
Diagnostic and prognostic nomograms for newly diagnosed intrahepatic cholangiocarcinoma with brain metastasis: A population-based analysis	10
New and effective method to develop primary hepatocytes from liver cancer patients	10
Vagal milieu or electrophysiologic substrate? The link between atrial fibrillation and obstructive sleep apnea	10
Antibiotic impregnation and nanocoating of external ventricular drainage catheters for antibacterial applications: Evaluation of in vitro studies and molecular docking	10
Single-cell RNA sequencing reveals differential expression of EGFL7 and VEGF in giant-cell tumor of bone and osteosarcoma	10
Penicillin-binding protein (PBP) inhibitor development: A 10-year chemical perspective	10
Overexpression of HOXA10 promotes the growth and metastasis of nasopharyngeal carcinoma	10
Influence of polymorphic variations of IFNL, HLA, and IL-6 genes in severe cases of COVID-19	10
Quantification of biomechanical properties of human corneal scar using acoustic radiation force optical coherence elastography	10
Improved protocol for Bst polymerase and reverse transcriptase production and application to a point-of-care diagnostics system	10
Molecular and environmental contributors to neurological complications in sickle cell disease	10
Complement factor H deficiency combined with smoking promotes retinal degeneration in a novel mouse model	9
2-Bromopalmitate inhibits malignant behaviors of HPSCC cells by hindering the membrane location of Ras protein	9
Progress in the contrary effects of glucagon-like peptide-1 and chemerin on obesity development	9
Leonurine pretreatment protects the heart from myocardial ischemia-reperfusion injury	9
Association between serum placental growth factor and vascular endothelial function in hyprtensive disorders complicating pregnancy	9
TRIM28 suppresses cancer stem-like characteristics in gastric cancer cells through Wnt/β-catenin signaling pathways	9
GP5 regulates epithelial–mesenchymal transition in breast cancer via the PI3K/AKT signaling pathway	9
Delayed tezampanel and caramiphen treatment but not midazolam protects against long-term neuropathology after soman exposure	9
Surface fibrils on the particles of nucleocytoviruses: A review	9
Comparison of circulating bacterial profiles between mild and severe COVID-19 patients	9
Effect of the ratio of vessel-specific volume to fractional myocardial mass on fractional flow reserve	9
Enhancing the sensitivity of ovarian cancer cells to olaparib via microRNA-20b-mediated cyclin D1 targeting	9
Data-driven approach to quantify trust in medical devices using Bayesian networks	9
Developing a SARS-CoV-2 main protease binding prediction random forest model for drug repurposing for COVID-19 treatment	9
Recombinant antigen delivery to dendritic cells as a way to improve vaccine design	9
Ultrasonographic assessment of skeletal muscles after experimentally induced neurogenic inflammation (facet injury) in rats	9
MicroRNA 205-5p and COVID-19 adverse outcomes: Potential molecular biomarker and regulator of the immune response	9
Systematic analysis of molecular characterization and clinical relevance of m6A regulators in digestive system pan-cancers	9
Prospective evaluation of optical coherence tomography for disease detection in the Casey mobile eye clinic	8
CRISPR/SaCas9-based gene editing rescues photoreceptor degeneration throughout a rhodopsin-associated autosomal dominant retinitis pigmentosa mouse model	8
Role of sex hormones in lung cancer	8
TXNIP activates NLRP3/IL-1β and participate in inflammatory response and oxidative stress to promote deep venous thrombosis	8
TRIM29 promotes the progression of colorectal cancer by suppressing EZH2 degradation	8
Construction and predictive value of risk models of maternal serum alpha-fetoprotein variants and fetal open neural tube defects	8
Plasmodium vivax transcriptomics: What is new?	8
Febuxostat ameliorates APAP-induced acute liver injury by activating Keap1/Nrf2 and inhibiting TLR4/NF-κB p65 pathways	8
Intermittent hypoxia promotes the recovery of motor function in rats with cerebral ischemia by regulating mitochondrial function	8
Wnt signaling in biliary development, proliferation, and fibrosis	8
A comprehensive overview of PPM1A: From structure to disease	8
Role of follistatin-like protein 1 in liver diseases	8
Human stem cell–derived neurons and neural circuitry therapeutics: Next frontier in spinal cord injury repair	8
Testing lncRNAs signature as clinical stage–related prognostic markers in gastric cancer progression using TCGA database	8
Circulating lncRNAs NONHSAT054669.2 and ENST00000525337 can be used as early biomarkers of gestational diabetes mellitus	8
Perinatal methadone exposure attenuates myelination and induces oligodendrocyte apoptosis in neonatal rat brain	8
Whole-genome sequencing as a first-tier diagnostic framework for rare genetic diseases	8
Isotyping and quantitation of the humoral immune response to SARS-CoV-2	8
Na+/K+-ATPase DR region antibody ameliorated cardiac hypertrophy and fibrosis in rats with 5/6 nephrectomy	8

Monitoring and modulation of the tumor microenvironment for enhanced cancer modeling	8
Delivery of microRNA-21-sponge and pre-microRNA-122 by MS2 virus-like particles to therapeutically target hepatocellular carcinoma cells	8
The role of ketamine in major depressive disorders: Effects on parvalbumin-positive interneurons in hippocampus	8
Analysis of dengue fever disease in West Africa	8
Ceramides and other sphingolipids as predictors of incident dysglycemia (CASPID): Design, methods, and baseline characteristics	7
The skeleton in a physical world	7
Succinate dehydrogenase complex subunit C: Role in cellular physiology and disease	7
Non-reference genome transposable elements (TEs) have a significant impact on the progression of the Parkinson’s disease	7
Synergetic enrichment of aggrecan in nucleus pulposus cells by scAAV6-shRNA-mediated knockdown of aggrecanase-1 and aggrecanase-2	7
Imbalance of follicular regulatory T (Tfr) cells/follicular helper T (Tfh) cells in adult patients with primary immune thrombocytopenia	7
Comparative study of optical coherence tomography angiography algorithms for rodent retinal imaging	7
Hypoxic colorectal cancer-secreted exosomes deliver miR-210-3p to normoxic tumor cells to elicit a protumoral effect	7
Nanocarrier-mediated curcumin delivery: An adjuvant strategy for CNS disease treatment	7
X-linked hypophosphatemia, fibroblast growth factor 23 signaling, and craniosynostosis	7
Deletion of ghrelin alters tryptophan metabolism and exacerbates experimental ulcerative colitis in aged mice	7
Nicotinamide mononucleotide ameliorates acute lung injury by inducing mitonuclear protein imbalance and activating the UPRmt	7
Transcellular routes of blood–brain barrier disruption	7
Comorbidities involving parasitic diseases: A look at the benefits and complications	7
Absence of antibody responses to SARS-CoV-2 N protein in COVID-19 vaccine breakthrough cases	7
Effects of bone morphogenetic proteins on epithelial repair	7
Interpretation of anatomic correlates of outer retinal bands in optical coherence tomography	7
Link between m6A modification and infiltration characterization of tumor microenvironment in lung adenocarcinoma	7
Bio-hybrid electronic and photonic devices	7
Protective effect of dexmedetomidine on intestinal mucosal barrier function in rats after cardiopulmonary bypass	7
Modeling adaptive drug resistance of colorectal cancer and therapeutic interventions with tumor spheroids	7
The multifunctionality of expression systems in Bacillus subtilis: Emerging devices for the production of recombinant proteins	7
Bioactive, full-length parathyroid hormone delivered using an adeno-associated viral vector	7
Curcumin attenuates vascular calcification via the exosomal miR-92b-3p/KLF4 axis	7
Lipocalin-2, S100A8/A9, and cystatin C: Potential predictive biomarkers of cardiovascular complications in COVID-19	7
Developing portable widefield fundus camera for teleophthalmology: Technical challenges and potential solutions	7
Heterogeneity of humoral response patterns in mildly symptomatic, non-hospitalized COVID-19 patients: A one-year longitudinal study	6
Bee venom ameliorates cardiac dysfunction in diabetic hyperlipidemic rats	6
Effects of moderate-continuous and high-intensity interval aerobic training on cardiac function of spontaneously hypertensive rats	6
Complement component 3 mutations alter the longitudinal risk of pediatric malaria and severe malarial anemia	6
Inflammation and mitochondria in the pathogenesis of chronic Chagas disease cardiomyopathy	6
Triterpenoid CDDO-EA inhibits lipopolysaccharide-induced inflammatory responses in skeletal muscle cells through suppression of NF-κB	6
Topology and redescriptions detect multiple alternative biological pathways from clinical phenotypes	6
Decision rules for personalized statin treatment prescriptions over multi-objectives	6
Transcriptomic profiling of cerebrospinal fluid identifies ALS pathway enrichment and RNA biomarkers in MND individuals	6
Evolving techniques for reducing phantom limb pain	6
Effects of autoimmune abnormalities on skeletal muscle regeneration after needle puncture in mice	6
Identifying immune subtypes of uterine corpus endometrial carcinoma and a four-paired-lncRNA signature with immune-related lncRNAs	6
Mouse embryonic stem cells require multiple amino acids	6
Normative intercapillary distance and vessel density data in the temporal retina assessed by wide-field spectral-domain optical coherence tomography angiography	6
Intranasal administration of mitochondria improves spatial memory in olfactory bulbectomized mice	6
Preface: 2022 International Conference on Neuroprotective Agents	6
A metabolism-relevant signature as a predictor for prognosis and therapeutic response in pancreatic cancer	6
A novel multiple subdivision-based algorithm for quantitative assessment of retinal vascular tortuosity	6
Corrigendum to “CTRP3 protects against uric acid-induced endothelial injury by inhibiting inflammation and oxidase stress in rats”	6
Therapeutically leveraging GABAA receptors in cancer	6
The role of mediator complex subunit 19 in human diseases	6
EXPRESSION OF CONCERN: Chondroitin-4-Sulphate Reduced Oxidative Injury in Caerulein-Induced Pancreatitis in Mice: The Involvement of NF-κB Translocation and Apoptosis Activation	6
Revisiting the role of lysophosphatidic acid in stem cell biology	6
MiR-296-5p ameliorates deep venous thrombosis by inactivating S100A4	6
Protective antioxidative and anti-inflammatory actions of β-caryophyllene against sulfasalazine-induced nephrotoxicity in rat	6
Whole-genome analysis and evolutionary characterization of cervical and oral human papillomavirus 16	6
Decreased PPP1R3G in pre-eclampsia impairs human trophoblast invasion and migration via Akt/MMP-9 signaling pathway	6
Role of autophagy and its regulation by noncoding RNAs in ovarian cancer	6
Clinical applications of 3D normal and breast cancer organoids: A review of concepts and methods	6
TFPI and FXIII negatively and S100A8/A9 and Cystatin C positively correlate with D-dimer in COVID-19	6
Contusion concomitant with ischemia injury aggravates skeletal muscle necrosis and hinders muscle functional recovery	6
Single-nucleotide polymorphisms of TLR4 and GAS7 linked to primary open-angle glaucoma among patients of Shenyang, China	6
Imaging and artificial intelligence for progression of age-related macular degeneration	5
Everolimus-induced hyperpermeability of endothelial cells causes lung injury	5
Neonatal sevoflurane exposure induces long-term changes in dendritic morphology in juvenile rats and mice	5
Enriched environment as a nonpharmacological neuroprotective strategy	5
Physical activity and exercise as an essential medical strategy for the COVID-19 pandemic and beyond	5
Dietary supplementation with L-leucine reduces nitric oxide synthesis by endothelial cells of rats	5
Neutrophil extracellular traps contributing to atherosclerosis: From pathophysiology to clinical implications	5
Is graphene the rock upon which new era continuous glucose monitors could be built?	5
Is type 2 diabetes mellitus another intercellular junction-related disorder?	5
Secretory phospholipase A2 in SARS-CoV-2 infection and multisystem inflammatory syndrome in children (MIS-C)	5
Weighted gene co-expression network analysis reveals the hub genes associated with pulmonary hypertension	5
4-Octyl itaconate alleviates renal ischemia reperfusion injury by ameliorating endoplasmic reticulum stress via Nrf2 pathway	5
Alteration of endothelial permeability ensures cardiomyocyte survival from ischemic insult in the subendocardium of the heart	5
Decellularization of the human urethra for tissue engineering applications	5
Dietary supplementation with L-citrulline improves placental angiogenesis and embryonic survival in gilts	5
Sex differences in muscle SIRT1 and SIRT3 and exercise + weight loss effects on muscle sirtuins	5
Epigallocatechin-3-gallate attenuates myocardial fibrosis in diabetic rats by activating autophagy	5
Corrigendum	5
Islet cell encapsulation – Application in diabetes treatment	5
CCNB1 promotes the development of hepatocellular carcinoma by mediating DNA replication in the cell cycle	5
Quantifying the progression of non-alcoholic fatty liver disease in human biomimetic liver microphysiology systems with fluorescent protein biosensors	5
Reduced expression of transmembrane protein 43 during cardiac hypertrophy leads to worsening heart failure in mice	5
Ultrasound in ocular oncology: Technical advances, clinical applications, and limitations	5
Mechanisms maintaining cerebral perfusion during systemic hypotension are impaired in elderly adults	5
The U.S. Food and Drug Administration, the mechanism of action, and other considerations for cell-based therapy candidates	5
Mesenchymal stem cells with p38 mitogen-activated protein kinase interference ameliorate mouse ischemic stroke	5
Role of long interspersed nuclear element-1 in the regulation of chromatin landscapes and genome dynamics	5
N-acetylcysteine improves autism-like behavior by recovering autophagic deficiency and decreasing Notch-1/Hes-1 pathway activity	5
A review on photo-mediated ultrasound therapy	5
Protective effect of astaxanthin on tuberculosis-associated inflammatory lung injury	5
Bacterial microbiota in upper respiratory tract of COVID-19 and influenza patients	5
Renal cystic disease in tuberous sclerosis complex	5
Convalescent serum-derived exosomes: Attractive niche as COVID-19 diagnostic tool and vehicle for mRNA delivery	5