Experimental Biology and Medicine

Article	Citations
Green synthesized silver nanoparticles for the treatment of diabetes and the related complications of hyperlipidemia and oxidative stress in diabetic rats	109
Dual detection of COVID-19 antigens and antibodies using nanoscale fluorescent plasmonic substrates	45
Circulating exosomal microRNA-4497 as a potential biomarker for metastasis and prognosis in non-small-cell lung cancer	40
Roles of IL-33 in the Pathogenesis of Cardiac Disorders	39
Participation of ASK-1 in the cardiomyocyte-protective role of mechanical ventilation in a rat model of myocardial infarction	38
Bioinformatics analysis of the genes associated with co-occurrence of heart failure and lung cancer	34
Wogonin, as a potent anticancer compound: From chemistry to cellular interactions	34
The continuing evolution of barcode applications: Functional toxicology to cell lineage	32
The influence of multidisciplinary team clinic on the prognosis of patients with chronic kidney disease	32
Paraoxonase 1 rs662 polymorphism, its related variables, and COVID-19 intensity: Considering gender and post-COVID complications	32
Autotaxin–lysophosphatidic acid receptor 5 axis evokes endothelial dysfunction via reactive oxygen species signaling	31
Combining tissue clearing and Fluoro-Jade C labeling for neurotoxicity assessments	31
S-allylmercapto-N-acetylcysteine protects bone cells from oxidation and improves femur microarchitecture in healthy and diabetic mice	29
Classification of salivary bacteriome in asymptomatic COVID-19 cases based on long-read nanopore sequencing	29
Gentiopicroside alleviates acute myocardial infarction injury in rats by disrupting Nrf2/NLRP3 signaling	28
Data science in drug discovery safety: Challenges and opportunities	28
Indoxyl sulfate impairs in vitro erythropoiesis by triggering apoptosis and senescence	26
Serum homocysteine is a valuable marker for predicting aggravation of infection in intestinal obstruction patients	26
Phenotyping in clinical text with unsupervised numerical reasoning for patient stratification	26
A primordial target: Mitochondria mediate both primary and collateral anesthetic effects of volatile anesthetics	26
Assessments of tumor mutational burden estimation by targeted panel sequencing: A comprehensive simulation analysis	25
Retraction Notice	25
Dysregulation of multiple signaling pathways: A possible cause of cerebral palsy	24
Structural and molecular biology of Sabiá virus	24
Inferences of carboplatin response-related signature by integrating multiomics data in ovarian serous cystadenocarcinoma	23

Thermo- and pH-sensitive nanoparticles of poly (N-isopropylacrylamide-decenoic acid-1-vinylimidazole) for ultrasound switchable fluorescence imaging	23
The role of IL-33/ST2 signaling in the tumor microenvironment and Treg immunotherapy	22
Interleukin-10 regulates starvation-induced autophagy through the STAT3-mTOR-p70s6k axis in hepatic stellate cells	22
Explainable hierarchical clustering for patient subtyping and risk prediction	22
Exogenous surfactant reduces inflammation and redox imbalance in rats under prone or supine mechanical ventilation	22
Classifying and evaluating fetuses with multicystic dysplastic kidney in etiologic studies	20
Fluoride induces osteoblast autophagy by inhibiting the PI3K/AKT/mTOR signaling pathway in vivo and in vitro	20
Beclin1- and Atg13-dependent autophagy activation and morroniside have synergistic effect on osteoblastogenesis	20
Macrophage polarization in hypoxia and ischemia/reperfusion: Insights into the role of energetic metabolism	20
TBX1 regulates myogenic differentiation by activating the TGFβ-Smad2/3 pathway in myoblasts	20
In-ovo imaging using ostrich eggs: Biomagnetism for detection of cardiac signals and embryonal motion	20
Gene expression profile suggests different mechanisms underlying sporadic and familial mesial temporal lobe epilepsy	20
Arbovirus surveillance in mosquitoes: Historical methods, emerging technologies, and challenges ahead	19
Manipulation of unfolded protein response by zoonotic vaccinia virus strains Guarani P1 and Passatempo	19
Evaluation of the mechanisms of heme-induced tissue factor activation: Contribution of innate immune pathways	19
Corrigendum	19
Statistical considerations for outcomes in clinical research: A review of common data types and methodology	19
Hydroxytyrosol produced by engineered Escherichia coli strains activates Nrf2/HO-1 pathway: An in vitro and in vivo study	18
Expression of cytoskeleton-associated protein 4 is associated with poor prognosis and metastasis in nasopharyngeal carcinoma	18
Dapagliflozin-entresto protected kidney from renal hypertension via downregulating cell-stress signaling and upregulating SIRT1/PGC-1α/Mfn2-medicated mitochondrial homeostasis	18
Mechanisms of disease-associated SINE-VNTR-Alus	18
The contribution of the immune system to genitourinary fibrosis	18
Artificial neural network–based diagnostic models for lung cancer combining conventional indicators with tumor markers	18
A novel fluorescent traceable carbon quantum dots with selective antibacterial activity against Porphyromonas gingivalis	18
LOXL2 reduces 5-FU sensitivity through the Hedgehog/BCL2 signaling pathway in colorectal cancer	17
JAK inhibitors for the treatment of VEXAS syndrome	17
Synthesis of glycine from 4-hydroxyproline in tissues of neonatal pigs	17
The inducible prostaglandin E synthase (mPGES-1) in neuroinflammatory disorders	17
Effect of smoking on the redox status of knee osteoarthritis: A preliminary study	17
Review on ultrasound-guided photoacoustic imaging for complementary analyses of biological systems in vivo	16
Rhubarb extract rebuilding the mucus homeostasis and regulating mucin-associated flora to relieve constipation	16
GDF15plays a critical role in insulin secretion in INS-1 cells and human pancreatic islets	16
Tastin promotes non-small-cell lung cancer progression through the ErbB4, PI3K/AKT, and ERK1/2 pathways	16
Repurposing medications for treatment of age-related macular degeneration: Insights from novel approaches to data mining	15
Visceral fat sympathectomy ameliorates systemic and local stress response related to chronic sleep restriction	15
The dengue virus 4 component of NIAID’s tetravalent TV003 vaccine drives its innate immune signature	15
Plasma Galectin-3 and H-FABP correlate with poor physical performance in patients with congestive heart failure	14
RxBERT: Enhancing drug labeling text mining and analysis with AI language modeling	14
Metformin inhibits mitochondrial dysfunction and apoptosis in cardiomyocytes induced by high glucose via upregulating AMPK activity	14
Alpha-linolenic acid enhances the facilitation of GABAergic neurotransmission in the BLA and CA1	14
Elevated SARS-CoV-2 in peripheral blood and increased COVID-19 severity in American Indians/Alaska Natives	14
COVID-19 active case findings based on self-collected saliva samples with CRISPR-Cas12a detection	13
Deep learning diagnostic performance and visual insights in differentiating benign and malignant thyroid nodules on ultrasound images	13
Seasonal variation and disease distribution of cytophagocytic mononuclear cells in synovial fluid: A medical record study	13
Epstein-Barr virus genotype-1 and Mediterranean + strain in gastric cancer biopsies of Ghanaian patients	13
Comparative transcriptome analysis of endothelial progenitor cells of HbSS patients with and without proliferative retinopathy	13
Allele-specific silencing by RNAi of R92Q and R173W mutations in cardiac troponin T	13
Revolutionized virome research using systems microbiology approaches	13
Applied artificial intelligence in healthcare: Listening to the winds of change in a post-COVID-19 world	12
How S100B crosses brain barriers and why it is considered a peripheral marker of brain injury	12

Proteomics analysis of carotid body tumor revealed potential mechanisms and molecular differences among Shamblin classifications	12
A quantum-based oversampling method for classification of highly imbalanced and overlapped data	12
An increase in polyadenylation of histone isoforms, Hist1h2ah and Hist2h3c2, is governed by 3′-UTR in de-differentiated and undifferentiated hepatocyte	12
Therapeutic effects of kartogenin on temporomandibular joint injury by activating the TGF-β/SMAD pathway in rats	12
Analyses of lung cancer-derived volatiles in exhaled breath and in vitro models	12
Apelin-13 prevents the effects of oxygen–glucose deprivation/reperfusion on bEnd.3 cells by inhibiting AKT–mTOR signaling	12
Aedes-borne orthoflavivirus infections in neotropical primates – Ecology, susceptibility, and pathogenesis	12
Respiratory viral infection and resolution of inflammation: Roles for specialized pro-resolving mediators	12
Diagnostic and prognostic nomograms for newly diagnosed intrahepatic cholangiocarcinoma with brain metastasis: A population-based analysis	12
Resistin stimulates PC-3 prostate cancer cell growth through stimulation of SOCS3 and SOCS5 genes	12
New and effective method to develop primary hepatocytes from liver cancer patients	11
Single-cell RNA sequencing reveals differential expression of EGFL7 and VEGF in giant-cell tumor of bone and osteosarcoma	11
Penicillin-binding protein (PBP) inhibitor development: A 10-year chemical perspective	11
Antibiotic impregnation and nanocoating of external ventricular drainage catheters for antibacterial applications: Evaluation of in vitro studies and molecular docking	11
TRIM28 suppresses cancer stem-like characteristics in gastric cancer cells through Wnt/β-catenin signaling pathways	11
Recombinant antigen delivery to dendritic cells as a way to improve vaccine design	11
Influence of polymorphic variations of IFNL, HLA, and IL-6 genes in severe cases of COVID-19	11
Changes in gene expression and neuroinflammation in the hippocampus of rats with poststroke cognitive impairment	11
Molecular and environmental contributors to neurological complications in sickle cell disease	11
MicroRNA 205-5p and COVID-19 adverse outcomes: Potential molecular biomarker and regulator of the immune response	11
Comparison of circulating bacterial profiles between mild and severe COVID-19 patients	11
The β-catenin/CBP signaling axis participates in sepsis-induced inflammatory lung injury	11
Eugenol alleviates neuronal damage via inhibiting inflammatory process against pilocarpine-induced status epilepticus	11
Vagal milieu or electrophysiologic substrate? The link between atrial fibrillation and obstructive sleep apnea	11
Improved protocol for Bst polymerase and reverse transcriptase production and application to a point-of-care diagnostics system	11
Na+/K+-ATPase DR region antibody ameliorated cardiac hypertrophy and fibrosis in rats with 5/6 nephrectomy	10
Role of follistatin-like protein 1 in liver diseases	10
Surface fibrils on the particles of nucleocytoviruses: A review	10
GP5 regulates epithelial–mesenchymal transition in breast cancer via the PI3K/AKT signaling pathway	10
CRISPR/SaCas9-based gene editing rescues photoreceptor degeneration throughout a rhodopsin-associated autosomal dominant retinitis pigmentosa mouse model	10
Ultrasonographic assessment of skeletal muscles after experimentally induced neurogenic inflammation (facet injury) in rats	10
Progress in the contrary effects of glucagon-like peptide-1 and chemerin on obesity development	10
Isotyping and quantitation of the humoral immune response to SARS-CoV-2	10
2-Bromopalmitate inhibits malignant behaviors of HPSCC cells by hindering the membrane location of Ras protein	10
Leonurine pretreatment protects the heart from myocardial ischemia-reperfusion injury	10
Monitoring and modulation of the tumor microenvironment for enhanced cancer modeling	9
Testing lncRNAs signature as clinical stage–related prognostic markers in gastric cancer progression using TCGA database	9
Perinatal methadone exposure attenuates myelination and induces oligodendrocyte apoptosis in neonatal rat brain	9
Human stem cell–derived neurons and neural circuitry therapeutics: Next frontier in spinal cord injury repair	9
Circulating lncRNAs NONHSAT054669.2 and ENST00000525337 can be used as early biomarkers of gestational diabetes mellitus	9
TXNIP activates NLRP3/IL-1β and participate in inflammatory response and oxidative stress to promote deep venous thrombosis	9
Non-reference genome transposable elements (TEs) have a significant impact on the progression of the Parkinson’s disease	9
The role of ketamine in major depressive disorders: Effects on parvalbumin-positive interneurons in hippocampus	9
Delayed tezampanel and caramiphen treatment but not midazolam protects against long-term neuropathology after soman exposure	9
Developing a SARS-CoV-2 main protease binding prediction random forest model for drug repurposing for COVID-19 treatment	9
TRIM29 promotes the progression of colorectal cancer by suppressing EZH2 degradation	9
Analysis of dengue fever disease in West Africa	9
Transcellular routes of blood–brain barrier disruption	9
Plasmodium vivax transcriptomics: What is new?	9
Data-driven approach to quantify trust in medical devices using Bayesian networks	9
Construction and predictive value of risk models of maternal serum alpha-fetoprotein variants and fetal open neural tube defects	9
Febuxostat ameliorates APAP-induced acute liver injury by activating Keap1/Nrf2 and inhibiting TLR4/NF-κB p65 pathways	9
Synergetic enrichment of aggrecan in nucleus pulposus cells by scAAV6-shRNA-mediated knockdown of aggrecanase-1 and aggrecanase-2	9
Intermittent hypoxia promotes the recovery of motor function in rats with cerebral ischemia by regulating mitochondrial function	9
Nicotinamide mononucleotide ameliorates acute lung injury by inducing mitonuclear protein imbalance and activating the UPRmt	8
Comorbidities involving parasitic diseases: A look at the benefits and complications	8
Inflammation and mitochondria in the pathogenesis of chronic Chagas disease cardiomyopathy	8
Preface: 2022 International Conference on Neuroprotective Agents	8
Ceramides and other sphingolipids as predictors of incident dysglycemia (CASPID): Design, methods, and baseline characteristics	8
Bioactive, full-length parathyroid hormone delivered using an adeno-associated viral vector	8
Nanocarrier-mediated curcumin delivery: An adjuvant strategy for CNS disease treatment	8
Deletion of ghrelin alters tryptophan metabolism and exacerbates experimental ulcerative colitis in aged mice	8
Bio-hybrid electronic and photonic devices	8
Triterpenoid CDDO-EA inhibits lipopolysaccharide-induced inflammatory responses in skeletal muscle cells through suppression of NF-κB	8
Topology and redescriptions detect multiple alternative biological pathways from clinical phenotypes	8
Succinate dehydrogenase complex subunit C: Role in cellular physiology and disease	8
Imbalance of follicular regulatory T (Tfr) cells/follicular helper T (Tfh) cells in adult patients with primary immune thrombocytopenia	8
X-linked hypophosphatemia, fibroblast growth factor 23 signaling, and craniosynostosis	8
The skeleton in a physical world	8
Whole-genome analysis and evolutionary characterization of cervical and oral human papillomavirus 16	8
Corrigendum to “CTRP3 protects against uric acid-induced endothelial injury by inhibiting inflammation and oxidase stress in rats”	8
Curcumin attenuates vascular calcification via the exosomal miR-92b-3p/KLF4 axis	8
Absence of antibody responses to SARS-CoV-2 N protein in COVID-19 vaccine breakthrough cases	8
Link between m6A modification and infiltration characterization of tumor microenvironment in lung adenocarcinoma	8
Single-nucleotide polymorphisms of TLR4 and GAS7 linked to primary open-angle glaucoma among patients of Shenyang, China	7
EXPRESSION OF CONCERN: Chondroitin-4-Sulphate Reduced Oxidative Injury in Caerulein-Induced Pancreatitis in Mice: The Involvement of NF-κB Translocation and Apoptosis Activation	7
Clinical applications of 3D normal and breast cancer organoids: A review of concepts and methods	7
Decision rules for personalized statin treatment prescriptions over multi-objectives	7
Transcriptomic profiling of cerebrospinal fluid identifies ALS pathway enrichment and RNA biomarkers in MND individuals	7
N-acetylcysteine improves autism-like behavior by recovering autophagic deficiency and decreasing Notch-1/Hes-1 pathway activity	7

Epigallocatechin-3-gallate attenuates myocardial fibrosis in diabetic rats by activating autophagy	7
TFPI and FXIII negatively and S100A8/A9 and Cystatin C positively correlate with D-dimer in COVID-19	7
Effects of autoimmune abnormalities on skeletal muscle regeneration after needle puncture in mice	7
Heterogeneity of humoral response patterns in mildly symptomatic, non-hospitalized COVID-19 patients: A one-year longitudinal study	7
Decreased PPP1R3G in pre-eclampsia impairs human trophoblast invasion and migration via Akt/MMP-9 signaling pathway	7
Role of autophagy and its regulation by noncoding RNAs in ovarian cancer	7
Enriched environment as a nonpharmacological neuroprotective strategy	7
Neutrophil extracellular traps contributing to atherosclerosis: From pathophysiology to clinical implications	7
Dietary supplementation with L-leucine reduces nitric oxide synthesis by endothelial cells of rats	7
Evolving techniques for reducing phantom limb pain	7
Effects of moderate-continuous and high-intensity interval aerobic training on cardiac function of spontaneously hypertensive rats	7
Protective antioxidative and anti-inflammatory actions of β-caryophyllene against sulfasalazine-induced nephrotoxicity in rat	7
Lipocalin-2, S100A8/A9, and cystatin C: Potential predictive biomarkers of cardiovascular complications in COVID-19	7
Mouse embryonic stem cells require multiple amino acids	7
A review on photo-mediated ultrasound therapy	7
Implications of fibrotic extracellular matrix in diabetic retinopathy	7
Contusion concomitant with ischemia injury aggravates skeletal muscle necrosis and hinders muscle functional recovery	7
Mesenchymal stem cells with p38 mitogen-activated protein kinase interference ameliorate mouse ischemic stroke	7
Antiviral activity of medicinal plant-derived products against SARS-CoV-2	6
Decellularization of the human urethra for tissue engineering applications	6
What does desmin do: A bibliometric assessment of the functions of the muscle intermediate filament	6
The U.S. Food and Drug Administration, the mechanism of action, and other considerations for cell-based therapy candidates	6
Mechanisms maintaining cerebral perfusion during systemic hypotension are impaired in elderly adults	6
Neonatal sevoflurane exposure induces long-term changes in dendritic morphology in juvenile rats and mice	6
Sex differences in muscle SIRT1 and SIRT3 and exercise + weight loss effects on muscle sirtuins	6
Targeting endothelial coagulation signaling ameliorates liver obstructive cholestasis and dysfunctional angiogenesis	6
Reduced expression of transmembrane protein 43 during cardiac hypertrophy leads to worsening heart failure in mice	6
Everolimus-induced hyperpermeability of endothelial cells causes lung injury	6
Corrigendum	6
Identification and validation of hub genes in CD5-positive diffuse large B-cell lymphoma	6
CX3CR1 deficiency exacerbates immune-mediated hepatitis by increasing NF-κB-mediated cytokine production in macrophage and T cell	6
Protective effect of astaxanthin on tuberculosis-associated inflammatory lung injury	6
Alteration of endothelial permeability ensures cardiomyocyte survival from ischemic insult in the subendocardium of the heart	6
Is type 2 diabetes mellitus another intercellular junction-related disorder?	6
MicroRNA regulation of BAG3	5
Convalescent serum-derived exosomes: Attractive niche as COVID-19 diagnostic tool and vehicle for mRNA delivery	5
4-Octyl itaconate alleviates renal ischemia reperfusion injury by ameliorating endoplasmic reticulum stress via Nrf2 pathway	5
Dietary supplementation with L-citrulline improves placental angiogenesis and embryonic survival in gilts	5
Habitual physical activity improves vagal cardiac modulation and carotid baroreflex function in elderly women	5
Epigallocatechin-3-gallate ameliorates renal endoplasmic reticulum stress-mediated inflammation in type 2 diabetic rats	5
Transcriptomic profile of the mechanosensitive ion channelome in human cardiac fibroblasts	5
Identification of key genes involved in calcific aortic valve disease based on integrated bioinformatics analysis	5
Risk factors for neonatal VAP: A retrospective cohort study	5
Intra-tumor heterogeneity and prognostic risk signature for hepatocellular carcinoma based on single-cell analysis	5
Oocyte cumulus complex quality and oviduct transportation velocity in systemic autoimmune disease model mice	5
Retraction Notice	5
Longitudinal intronic RNA-Seq analysis of Parkinson’s disease patients reveals disease-specific nascent transcription	5
Evaluation methodology for deep learning imputation models	5
An overview of viral chitinases: General properties and biotechnological potential	5
Weighted gene co-expression network analysis reveals the hub genes associated with pulmonary hypertension	5
Returning to basic principles to develop more effective treatments for central nervous system disorders	5
Pink1 promotes cell proliferation and affects glycolysis in breast cancer	5
TGFβ1 induces CXCL1 to promote stemness features in lung cancer	5
Therapeutic strategies to improve liver regeneration after hepatectomy	5
GPER1 contributes to T3-induced osteogenesis by mediating glycolysis in osteoblast precursors	5
Development of a novel purification protocol to isolate and identify brain microglia	5
A systematic analysis and data mining of opioid-related adverse events submitted to the FAERS database	5
Paricalcitol protects against hydrogen peroxide–induced injury in endothelial cells through suppression of apoptosis	5
Quercetin suppresses ovariectomy-induced osteoporosis in rat mandibles by regulating autophagy and the NLRP3 pathway	5
Clinical and genetic investigations in Chinese families with retinitis pigmentosa	5
Gene expression patterns and related pathways in the hearts of rhesus monkeys subjected to prolonged myocardial ischemia	5
Ultrasound in ocular oncology: Technical advances, clinical applications, and limitations	5
Is graphene the rock upon which new era continuous glucose monitors could be built?	5
Unraveling the physiologic paradoxes that underlie exercise prescription for stress fracture prevention	5
Quercetin supplementation attenuates airway hyperreactivity and restores airway relaxation in rat pups exposed to hyperoxia	5
Differential expression profile of plasma exosomal microRNAs in chronic rhinosinusitis with nasal polyps	5
Mechanisms of cell injury induced by inhaled molybdenum trioxide nanoparticles in Golden Syrian Hamsters	5
Metformin and retinal diseases in preclinical and clinical studies: Insights and review of literature	5
Photoacoustic imaging systems based on clinical ultrasound platform	5
In vivo visualization and analysis of ciliary motion in allergic rhinitis models induced by ovalbumin	5
Corilagin alleviates intestinal ischemia/reperfusion injury by relieving oxidative stress and apoptosis via AMPK/Sirt1-autophagy pathway	5
MiRNA-470-5p suppresses epithelial-mesenchymal transition of embryonic palatal shelf epithelial cells by targeting Fgfr1 during palatogenesis	5