OOIR: Observatory of International Research

Papers

(The median citation count of Neuromolecular Medicine is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Bile Acids: A Communication Channel in the Gut-Brain Axis	72
Recent Insights on the Role of PPAR-β/δ in Neuroinflammation and Neurodegeneration, and Its Potential Target for Therapy	50
Effect of Ergothioneine on 7-Ketocholesterol-Induced Endothelial Injury	31
Specific Susceptibility to COVID-19 in Adults with Down Syndrome	28
Gastrodin Regulates the Notch Signaling Pathway and Sirt3 in Activated Microglia in Cerebral Hypoxic-Ischemia Neonatal Rats and in Activated BV-2 Microglia	25
Wnt Signaling Pathways: A Role in Pain Processing	22
Cell-Free Extracellular Vesicles Derived from Human Bone Marrow Endothelial Progenitor Cells as Potential Therapeutics for Microvascular Endothelium Restoration in ALS	22
High-Intensity Functional Training: Molecular Mechanisms and Benefits	21
Lipidomic Analysis of Postmortem Prefrontal Cortex Phospholipids Reveals Changes in Choline Plasmalogen Containing Docosahexaenoic Acid and Stearic Acid Between Cases With and Without Alzheimer’s Dise	18
Targeting Mitochondrial Oxidative Phosphorylation in Glioblastoma Therapy	18
Repurposing Vorinostat for the Treatment of Disorders Affecting Brain	17
Exosomes Derived Neuronal Markers: Immunoaffinity Isolation and Characterization	17
The Role of lncRNA TUG1 in the Parkinson Disease and Its Effect on Microglial Inflammatory Response	17
Oxytocin Reduces Brain Injury and Maintains Blood–Brain Barrier Integrity After Ischemic Stroke in Mice	16
Sphingosine 1-Phosphate Receptors in Cerebral Ischemia	14
Lysophosphatidic Acid Signalling in Nervous System Development and Function	14
The Biological Activity of 3-O-Acetyl-11-keto-β-Boswellic Acid in Nervous System Diseases	14
The Gut Ecosystem: A Critical Player in Stroke	13
Gastrodin Attenuates Lipopolysaccharide-Induced Inflammatory Response and Migration via the Notch-1 Signaling Pathway in Activated Microglia	13
Mesenchymal Stem Cell-Derived Exosomes Improved Cerebral Infarction via Transferring miR-23a-3p to Activate Microglia	13
Galectin-9 Promotes Neuronal Restoration via Binding TLR-4 in a Rat Intracerebral Hemorrhage Model	12
The Effect of Histone Deacetylase Inhibitors Panobinostat or Entinostat on Motor Recovery in Mice After Ischemic Stroke	12
Tranilast, a Transient Receptor Potential Vanilloid 2 Channel (TRPV2) Inhibitor Attenuates Amyloid β-Induced Cognitive Impairment: Possible Mechanisms	12
ACE2, Circumventricular Organs and the Hypothalamus, and COVID-19	12
Adult Hippocampal Neurogenesis: One Lactate to Rule Them All	11

Experimentally Induced Sepsis Causes Extensive Hypomyelination in the Prefrontal Cortex and Hippocampus in Neonatal Rats	11
Downregulation of Microrna-421 Relieves Cerebral Ischemia/Reperfusion Injuries: Involvement of Anti-apoptotic and Antioxidant Activities	10
Anti-inflammatory and Cytoprotective Effect of Clinacanthus nutans Leaf But Not Stem Extracts on 7-Ketocholesterol Induced Brain Endothelial Cell Injury	10
miR-146a Mimics Ameliorates Traumatic Brain Injury Involving JNK and NF-κB Signaling Pathway	10
LncRNA LINC00689 Promotes the Tumorigenesis of Glioma via Mediation of miR-526b-3p/IGF2BP1 Axis	10
The Identification of Blood Biomarkers of Chronic Neuropathic Pain by Comparative Transcriptomics	10
Diagnostic Performance of miR-485-3p in Patients with Parkinson’s Disease and its Relationship with Neuroinflammation	10
Sex Differences in Glioblastoma Immunotherapy Response	10
Application of Next-Generation Sequencing in Neurodegenerative Diseases: Opportunities and Challenges	10
Microarray Profiling Reveals Distinct Circulating miRNAs in Aged Male and Female Mice Subjected to Post-stroke Social Isolation	9
Contemporary RNA Therapeutics for Glioblastoma	9
HLA in Alzheimer’s Disease: Genetic Association and Possible Pathogenic Roles	9
Antioxidant Combo Therapy Protects White Matter After Traumatic Brain Injury	9
Sphingolipids as Regulators of Neuro-Inflammation and NADPH Oxidase 2	9
A Walnut Diet in Combination with Enriched Environment Improves Cognitive Function and Affects Lipid Metabolites in Brain and Liver of Aged NMRI Mice	9
Interleukin-1 Mediates Ischemic Brain Injury via Induction of IL-17A in γδ T Cells and CXCL1 in Astrocytes	9
CD137 Ligand-CD137 Interaction is Required For Inflammasome-Associated Brain Injury Following Ischemic Stroke	9
Implication of Paraprobiotics in Age-Associated Gut Dysbiosis and Neurodegenerative Diseases	9
IL-2/IL-2R Antibody Complex Enhances Treg-Induced Neuroprotection by Dampening TNF-α Inflammation in an In Vitro Stroke Model	9
Vitamin D3 Supplement Attenuates Blood–Brain Barrier Disruption and Cognitive Impairments in a Rat Model of Traumatic Brain Injury	9
Involvement of Microbiome Gut–Brain Axis in Neuroprotective Effect of Quercetin in Mouse Model of Repeated Mild Traumatic Brain Injury	8
Inhibition of microRNA-143-3p Attenuates Cerebral Ischemia/Reperfusion Injury by Targeting FSTL1	8
Tau and GSK-3β are Critical Contributors to α-Synuclein-Mediated Post-Stroke Brain Damage	8
Compound 21, a Direct AT2R Agonist, Induces IL-10 and Inhibits Inflammation in Mice Following Traumatic Brain Injury	8
Neuronal Exosomes Secreted under Oxygen–Glucose Deprivation/Reperfusion Presenting Differentially Expressed miRNAs and Affecting Neuronal Survival and Neurite Outgrowth	8
Molecular Classification of Gliomas is Associated with Seizure Control: A Retrospective Analysis	7
Long Noncoding RNA LINC01518 Modulates Proliferation and Migration in TGF-β1-Treated Human Tenon Capsule Fibroblast Cells Through the Regulation of hsa-miR-216b-5p	7
Extract of Polygala tenuifolia, Angelica tenuissima, and Dimocarpus longan Reduces Behavioral Defect and Enhances Autophagy in Experimental Models of Parkinson’s Disease	7
Emerging Epigenetic Therapies for Brain Tumors	7
Neuroinflammatory Modulation of Extracellular Vesicle Biogenesis and Cargo Loading	7
Association of Single Nucleotide Polymorphism at rs2275294 in the ZNF512B Gene with Prognosis in Amyotrophic Lateral Sclerosis	7
Association of CHRNA5 Gene Variants with Crack Cocaine Addiction	7
Defective Lysosomal Lipid Catabolism as a Common Pathogenic Mechanism for Dementia	7
Overexpression of miR-149-5p Attenuates Cerebral Ischemia/Reperfusion (I/R) Injury by Targeting Notch2	7
Dimethyl Itaconate Reduces Cognitive Impairment and Neuroinflammation in APPswe/PS1ΔE9 Transgenic Mouse Model of Alzheimer’s Disease	7
Butanol Extract of Tinospora cordifolia Alleviates Acute Sleep Deprivation-Induced Impairments in Cognitive Functions and Neuromuscular Coordination in Middle-Aged Female Rats	6
O-GlcNAc Transferase (OGT) Protects Cerebral Neurons from Death During Ischemia/Reperfusion (I/R) Injury by Modulating Drp1 in Mice	6
5-N-ethyl Carboxamidoadenosine Stimulates Adenosine-2b Receptor-Mediated Mitogen-Activated Protein Kinase Pathway to Improve Brain Mitochondrial Function in Amyloid Beta-Induced Cognitive Deficit Mice	6
Remote Ischemic Post-Conditioning Therapy is Protective in Mouse Model of Traumatic Optic Neuropathy	6
Preclinical and Clinical Evidence for the Involvement of Sphingosine 1-Phosphate Signaling in the Pathophysiology of Vascular Cognitive Impairment	6
Overexpressing SIRT6 can Attenuate the Injury of Intracerebral Hemorrhage by Down-Regulating NF-kB	6
MOG-Specific T Cells Lead to Spontaneous EAE with Multilocular B Cell Infiltration in the GF-IL23 Model	6
Quercetin Ameliorates CFA-Induced Chronic Inflammatory Hyperalgesia via Modulation of ROS-Mediated ERK1/2 Signaling and Inhibition of Spinal Glial Activation In Vivo	6
VEGF Modulates the Neural Dynamics of Hippocampal Subregions in Chronic Global Cerebral Ischemia Rats	6
Therapeutic Potential of Quercetin and its Derivatives in Epilepsy: Evidence from Preclinical Studies	5
Metabolic Switching of Cultured Mesenchymal Stem Cells Creates Super Mitochondria in Rescuing Ischemic Neurons	5
SIRT3 Regulates Neuronal Excitability of Alzheimer’s Disease Models in an Oxidative Stress-Dependent Manner	5
Spautin-1 Protects Against Mild TBI-Induced Anxiety-Like Behavior in Mice via Immunologically Silent Apoptosis	5
Activation of ephrinb1/EPHB2/MAP-2/NMDAR Mediates Hippocampal Neurogenesis Promoted by Transcranial Direct Current Stimulation in Cerebral-Ischemic Mice	5
Does Inflammation Play a Major Role in the Pathogenesis of Alzheimer's Disease?	5

Chimeric Antigen Receptor (CAR) T Cell Therapy for Glioblastoma	5
Gastrodin Regulates the Notch-1 Signal Pathway via Renin–Angiotensin System in Activated Microglia	5
Stem-Like Cell Populations, p53-Pathway Activation and Mechanisms of Recurrence in Sonic Hedgehog Medulloblastoma	5
SS-31 Improves Cognitive Function in Sepsis-Associated Encephalopathy by Inhibiting the Drp1-NLRP3 Inflammasome Activation	5
Preliminary Findings on Proline-Rich Protein 14 as a Diagnostic Biomarker for Parkinson’s Disease	5
MiR-5787 Attenuates Macrophages-Mediated Inflammation by Targeting TLR4/NF-κB in Ischemic Cerebral Infarction	5
Alpinia oxyphylla–Schisandra chinensis Herb Pair Alleviates Amyloid-β Induced Cognitive Deficits via PI3K/Akt/Gsk-3β/CREB Pathway	5
Revealing the Modular Similarities and Differences Among Alzheimer’s Disease, Vascular Dementia, and Parkinson’s Disease in Genomic Networks	5
Prostaglandin A2 Interacts with Nurr1 and Ameliorates Behavioral Deficits in Parkinson’s Disease Fly Model	5
Influence of Simulated Deep Brain Stimulation on the Expression of Inflammatory Mediators by Human Central Nervous System Cells In Vitro	5
Deoxysphingolipids Upregulate MMP-1, Downregulate TIMP-1, and Induce Cytotoxicity in Human Schwann Cells	5
CD33/TREM2 Signaling Mediates Sleep Deprivation-Induced Memory Impairment by Regulating Microglial Phagocytosis	5
The Effect of Ulinastatin to the Learning and Memory in Zebrafish	5