Developmental Cell

Article	Citations
Rim aperture of yeast autophagic membranes balances cargo inclusion with vesicle maturation	289
Therapeutic modulation of GSTO activity rescues FUS-associated neurotoxicity via deglutathionylation in ALS disease models	271
HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function	257
Partial closure of the γ-tubulin ring complex by CDK5RAP2 activates microtubule nucleation	180
Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients	176
Discrete cis-acting element regulates developmentally timed gene-lamina relocation and neural progenitor competence in vivo	165
Restoration of cone-circuit functionality in the regenerating adult zebrafish retina	157
TREX1-dependent DNA damage links nuclear rupture to tumor cell invasion	140
A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration	137
Diet suppresses glioblastoma initiation in mice by maintaining quiescence of mutation-bearing neural stem cells	124
Rapid and robust optogenetic control of gene expression in Drosophila	123
StBPA1 attenuates surface receptor activation and finely regulates immune responses against bacterial and oomycete pathogens in potato	121
A transcriptional and regulatory map of mouse somite maturation	121
Radially patterned morphogenesis of murine hair follicle placodes ensures robust epithelial budding	119
Epithelial cells adapt to curvature induction via transient active osmotic swelling	114
Control of poly(A)-tail length and translation in vertebrate oocytes and early embryos	114
Spatial patterning controls neuron numbers in the Drosophila visual system	111
SMARCA5 reprograms AKR1B1-mediated fructose metabolism to control leukemogenesis	109
cAMP controls a trafficking mechanism that maintains the neuron specificity and subcellular placement of electrical synapses	106
Epithelial tissue confinement inhibits cell growth and leads to volume-reducing divisions	104
Damage-responsive neuro-glial clusters coordinate the recruitment of dormant neural stem cells in Drosophila	98
Slc25a3-dependent copper transport controls flickering-induced Opa1 processing for mitochondrial safeguard	94
Mechanics of spindle orientation in human mitotic cells is determined by pulling forces on astral microtubules and clustering of cortical dynein	91
Astrocyte-induced mGluR1 activates human lung cancer brain metastasis via glutamate-dependent stabilization of EGFR	83
E3 ubiquitin ligase IPI1 controls rice immunity and flowering via both E3 ligase-dependent and -independent pathways	83

Maternal and embryonic signals cause functional differentiation of luminal epithelial cells and receptivity establishment	82
Organoids from pluripotent stem cells and human tissues: When two cultures meet each other	79
Bifunctional transcription factor GhMYB4 orchestrates transition from elongation to secondary cell wall synthesis trade-off in cotton fiber	78
ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress	75
Mechanisms of ferroptosis sensitization and resistance	71
Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy	71
A human breast atlas integrating single-cell proteomics and transcriptomics	70
How structural interactions and receptor phosphorylation shape strigolactone signaling in rice	70
Neuronal-epithelial cross-talk drives acinar specification via NRG1-ERBB3-mTORC2 signaling	69
YAP1 and PRDM14 converge to promote cell survival and tumorigenesis	69
Fibrous periosteum repairs bone fracture and maintains the healed bone throughout mouse adulthood	68
KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling	67
Dynamic control of H2A.Zub and H3K27me3 by ambient temperature during cell fate determination in Arabidopsis	65
Tumor-derived MMPs regulate cachexia in a Drosophila cancer model	65
Nuclear lamina phase separation orchestrates stress-induced transcriptional responses in plants	64
Nuclear receptor Nr5a2 promotes diverse connective tissue fates in the jaw	63
SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway	62
The miR-430 locus with extreme promoter density forms a transcription body during the minor wave of zygotic genome activation	61
Adaptive mechanoproperties mediated by the formin FMN1 characterize glioblastoma fitness for invasion	60
Genetic variation associated with condensate dysregulation in disease	60
Single-cell transcriptomic analysis highlights specific cell types manipulated by Fusarium head blight fungus leading to wheat susceptibility	60
Pollen-stigma incompatibility within and between species: Tread lightly, sedate the dogs, and don’t wake the guards!	59
Lysosomal catabolic activity promotes the exit of murine totipotent 2-cell state by silencing early-embryonic retrotransposons	59
MAP9/MAPH-9 supports axonemal microtubule doublets and modulates motor movement	58
Traveling to the left: A story of PKD1L1-containing vesicles	57
SUMO style defense: How post-translational modification via SUMO conjugation promotes plant defense	57
Temperature-responsive N-acetylcytidine mRNA modification controls thermosensory flowering in Arabidopsis	55
A condensates-to-VPS41-associated phagic vacuoles conversion pathway controls autophagy degradation in plants	55
Mannose controls mesoderm specification and symmetry breaking in mouse gastruloids	55
Axon guidance in central nervous system regeneration	55
An Oatp transporter-mediated steroid sink promotes tumor-induced cachexia in Drosophila	55
BMP-gated cell-cycle progression drives anoikis during mesenchymal collective migration	54
Seamless knockins in Drosophila via CRISPR-triggered single-strand annealing	54
Setting up cAMP in plants	54
Can’t smell the virus: SARS-CoV-2, chromatin organization, and anosmia	54
Stepping on the molecular brake: Slowing down proliferation to allow differentiation	54
The endophilin curvature-sensitive motif requires electrostatic guidance to recycle synaptic vesicles in vivo	53
Don’t fear the reaper: The role of regulated cell death in tumorigenesis and BH3-mimetics for cancer therapy	53
Bidirectional activation of stem-like programs between metastatic cancer and alveolar type 2 cells within the niche	52
Human yolk sac-derived innate lymphoid-biased multipotent progenitors emerge prior to hematopoietic stem cell formation	52
The microtubular preprophase band recruits Myosin XI to the cortical division site to guide phragmoplast expansion during plant cytokinesis	52
Vimentin intermediate filaments coordinate actin stress fibers and podosomes to determine the extracellular matrix degradation by macrophages	52
Xyloglucan side chains enable polysaccharide secretion to the plant cell wall	52
Nitric oxide controls stomatal development and stress responses by inhibiting MPK6 phosphorylation via S-nitrosylation in Arabidopsis	52
Nucleolar protein PEXF controls ribosomal RNA synthesis and pluripotency exit	51
Spatiotemporal mapping of gene expression landscapes and developmental trajectories during zebrafish embryogenesis	51
Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis	50
An antisense RNA forms R-loop to facilitate the transcription of CBF genes and plant cold acclimation	50
Immune mechanisms shape the clonal landscape during early progression of prostate cancer	49
Endosomal trafficking and DNA damage checkpoint kinases dictate survival to replication stress by regulating amino acid uptake and protein synthesis	49

CLMP is a tumor suppressor that determines all-trans retinoic acid response in colorectal cancer	48
Plant glutamate receptors mediate a bet-hedging strategy between regeneration and defense	47
Monomethyl branched-chain fatty acid mediates amino acid sensing upstream of mTORC1	47
Integrated transcriptomics of human blood vessels defines a spatially controlled niche for early mesenchymal progenitor cells	46
Pten, PI3K, and PtdIns(3,4,5)P3 dynamics control pulsatile actin branching in Drosophila retina morphogenesis	46
A single-cell census of mouse limb development identifies complex spatiotemporal dynamics of skeleton formation	45
Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method	45
Assembly of tight junction belts by ZO1 surface condensation and local actin polymerization	45
Optogenetic manipulation identifies the roles of ERK and AKT dynamics in controlling mouse embryonic stem cell exit from pluripotency	45
Bending toward differentiation	44
Extracellular matrix assembly stress initiates Drosophila central nervous system morphogenesis	43
Developmental landscape of human forebrain at a single-cell level identifies early waves of oligodendrogenesis	43
20 years of Developmental Cell: Looking forward	43
TDRD1 phase separation drives intermitochondrial cement assembly to promote piRNA biogenesis and fertility	42
VAMP2 controls murine epidermal differentiation and carcinogenesis by regulation of nucleophagy	42
Allelic transcriptomic profiling identifies the role of PRD-like homeobox genes in human embryonic-cleavage-stage arrest	42
Understanding the cell fate and behavior of progenitors at the origin of the mouse cardiac mitral valve	42
Seriously cilia: A tiny organelle illuminates evolution, disease, and intercellular communication	42
Smooth muscle contributes to the development and function of a layered intestinal stem cell niche	41
Vasculature is getting Hip(po): Hippo signaling in vascular development and disease	41
Investigating morphogen and patterning dynamics with optogenetic control of morphogen production	41
Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging	40
S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity	40
Localized glucose import, glycolytic processing, and mitochondria generate a focused ATP burst to power basement-membrane invasion	40
ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells	40
Septins regulate border cell surface geometry, shape, and motility downstream of Rho in Drosophila	40
Mechanical regulation of substrate adhesion and de-adhesion drives a cell-contractile wave during Drosophila tissue morphogenesis	40
RNA N6-methyladenosine modification promotes auxin biosynthesis required for male meiosis in rice	40
Chromatin remodeling of prostaglandin signaling in smooth muscle enables mouse embryo passage through the female reproductive tract	39
Spatially resolved proteomics of the Arabidopsis stomatal lineage identifies polarity complexes for cell divisions and stomatal pores	39
Transgenesis in the acoel worm Hofstenia miamia	39
Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation	38
Adhesion tunes speed and persistence by coordinating protrusions and extracellular matrix remodeling	38
Sweat gland development requires an eccrine dermal niche and couples two epidermal programs	37
GLRs: Mediating a defense-regeneration tradeoff in plants	37
Welcoming new Developmental Cell advisors	37
Mesodermal fibronectin controls cell shape, polarity, and mechanotransduction in the second heart field during cardiac outflow tract development	37
Distinct p53 isoforms code for opposing transcriptional outcomes	37
The BAS chromatin remodeler determines brassinosteroid-induced transcriptional activation and plant growth in Arabidopsis	37
Identification of Greb1l as a genetic determinant of crisscross heart in mice showing torsion of the heart tube by shortage of progenitor cells	36
Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells	36
Actomyosin contractility in olfactory placode neurons opens the skin epithelium to form the zebrafish nostril	36
Mitochondrial GTP metabolism controls reproductive aging in C. elegans	36
ZINC FINGER PROTEIN2 suppresses funiculus lignification to ensure seed loading efficiency in Arabidopsis	36
Deceleration of the cell cycle underpins a switch from proliferative to terminal divisions in plant stomatal lineage	35
Stress delays the bloom: ROS sustains condensates to protect the tomato meristem	35
PRC2-mediated repression of PIF4 targets beyond the on/off switch of gene expression	35
Extracellular carriers control lipid-dependent secretion, delivery, and activity of WNT morphogens	34
20 years of Developmental Cell: Looking back	34
A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase	34
A translation control module coordinates germline stem cell differentiation with ribosome biogenesis during Drosophila oogenesis	34
The Hitchhiker’s Guide across a Waddington’s landscape of melanoma	33
Collective oscillatory signaling in Dictyostelium discoideum acts as a developmental timer initiated by weak coupling of a noisy pulsatile signal	33
Gene module reconstruction identifies cellular differentiation processes and the regulatory logic of specialized secretion in zebrafish	33
Fate mapping in mouse demonstrates early secretory differentiation directly from Lgr5+ intestinal stem cells	33
Integration of vascular progenitors into functional blood vessels represents a distinct mechanism of vascular growth	33
A dual enhancer-attenuator element ensures transient Cdx2 expression during mouse posterior body formation	33
Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration	33
Building a kidney tree: Functional collecting duct from human pluripotent stem cells	33
Developmental angiocrine diversification of endothelial cells for organotypic regeneration	33
Evolutionarily conserved midbody remodeling precedes ring canal formation during gametogenesis	32
Mapping the dynamics of epigenetic adaptation in S. pombe during heterochromatin misregulation	32
4D reconstruction of murine developmental trajectories using spherical harmonics	32
Dual states of murine Bmi1-expressing intestinal stem cells drive epithelial development utilizing non-canonical Wnt signaling	32
Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster	32
S-nitrosylation coordinates stomatal development and functions	32
Long noncoding RNA ARTA controls ABA response through MYB7 nuclear trafficking in Arabidopsis	31
An exception to the rule? Regeneration of the injured spinal cord in the spiny mouse	31
Wnt signaling couples G2 phase control with differentiation during hematopoiesis in Drosophila	31
ZNFX-1 keeps RNAi in the loop	31
Quantitative proteomic profiling identifies global protein network dynamics in murine embryonic heart development	31
Persistent cell contacts enable E-cadherin/HMR-1- and PAR-3-based symmetry breaking within a developing C. elegans epithelium	31
PITTching in for lysosome repair	31
TAF1 is required for fetal but not adult hematopoiesis in mice	31
Antagonistic systemin receptors integrate the activation and attenuation of systemic wound signaling in tomato	30
Notochord segmentation in zebrafish controlled by iterative mechanical signaling	30
A chromatin code for limb segment identity in axolotl limb regeneration	30
ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer	30
Activity-dependent local protection and lateral inhibition control synaptic competition in developing mitral cells in mice	30
A Scribble/Cdep/Rac pathway controls follower-cell crawling and cluster cohesion during collective border-cell migration	30

Force-dependent activation of actin elongation factor mDia1 protects the cytoskeleton from mechanical damage and promotes stress fiber repair	29
Concerted changes in Epithelium and Stroma: a multi-scale, multi-omics analysis of progression from Barrett’s Esophagus to adenocarcinoma	29
Asymmetric partitioning of persistent paternal mitochondria during cell divisions safeguards embryo development and mitochondrial inheritance	29
Detection of surface forces by the cell-wall mechanosensor Wsc1 in yeast	29
Hepatocytic lipocalin-2 controls HDL metabolism and atherosclerosis via Nedd4-1-SR-BI axis in mice	29
A subset of neutrophils activates anti-tumor immunity and inhibits non-small-cell lung cancer progression	29
Morphogenesis and regeneration share a conserved core transition cell state program that controls lung epithelial cell fate	29
In the mouse cortex, oligodendrocytes regain a plastic capacity, transforming into astrocytes after acute injury	29
Cell death: Revisiting the roads to ruin	28
DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice	28
Aging-induced changes in lymphatic muscle cell transcriptomes are associated with reduced pumping of peripheral collecting lymphatic vessels in mice	28
How meningeal macrophages control medulloblastoma induction	28
Reshaping of the tumor microenvironment by cellular senescence: An opportunity for senotherapies	28
Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation	28
YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth	28
EYA protein complex is required for Wntless retrograde trafficking from endosomes to Golgi	28
Human yolk sac-derived innate lymphoid-biased multipotent progenitors emerge prior to hematopoietic stem cell formation	27
Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD	27
TaANK-TPR1 enhances wheat resistance against stripe rust via controlling gene expression and protein activity of NLR protein TaRPP13L1	27
Meningeal macrophages inhibit chemokine signaling in pre-tumor cells to suppress mouse medulloblastoma initiation	27
Glutamine-dependent signaling controls pluripotent stem cell fate	27
Self-extinguishing relay waves enable homeostatic control of human neutrophil swarming	27
An integrated approach identifies the molecular underpinnings of murine anterior visceral endoderm migration	27
Mending microtubules enhances cell polarity	27
Marsupial single-cell transcriptomics identifies temporal diversity in mammalian developmental programs	27
The mechanical state of pre-tumoral epithelia controls subsequent Drosophila tumor aggressiveness	26
Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover	26
From nuclear to extracellular PTEN: Multiple roles in tumor suppression and immune modulation	26
A limb bud morphogen bites the dust	26
Cytoskeletal crosstalk in macrophages: Vimentin drives ECM remodeling in tumor invasion and tissue plasticity	26
Single-cell chromatin accessibility identifies enhancer networks driving gene expression during spinal cord development in mouse	26
SigmaR1 shapes rough endoplasmic reticulum membrane sheets	26
A postsynaptic GPR158-PLCXD2 complex controls spine apparatus abundance and dendritic spine maturation	26
Molecular and spatial landmarks of early mouse skin development	26
ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion	26
Controlling pyroptosis through post-translational modifications of gasdermin D	26
Microtubule-associated protein MAP7 promotes tubulin posttranslational modifications and cargo transport to enable osmotic adaptation	26
Lineage-tracing hematopoietic stem cell origins in vivo to efficiently make human HLF+ HOXA+ hematopoietic progenitors from pluripotent stem cells	26
Giving translation a hand	26
The elusive pulmonary neuroendocrine cell: How rare diseases may help solving common diseases	26
An SLC12A9-dependent ion transport mechanism maintains lysosomal osmolarity	25
H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity	25
Identification of a non-canonical planar cell polarity pathway triggered by light in the developing mouse retina	25
Ubiquitin ligase MARCH5 controls the formation of mitochondria-derived pre-peroxisomes	25
Differential condensation of sister chromatids acts with Cdc6 to ensure asynchronous S-phase entry in Drosophila male germline stem cell lineage	25
Endoplasmic reticulum exit sites are segregated for secretion based on cargo size	25
A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression	24
Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye	24
Jpx RNA controls Xist induction through spatial reorganization of the mouse X-inactivation center	24
Plasticity in airway smooth muscle differentiation during mouse lung development	24
The Drosophila adult midgut progenitor cells arise from asymmetric divisions of neuroblast-like cells	24
Kinetochore life histories reveal an Aurora-B-dependent error correction mechanism in anaphase	24
Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon	24
Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation	24
Acute brain vascular regeneration occurs via lymphatic transdifferentiation	24
Regulation of reverse electron transfer at mitochondrial complex I by unconventional Notch action in cancer stem cells	24
DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential	24
Heart regeneration: 20 years of progress and renewed optimism	23
Caveolae sense oxidative stress through membrane lipid peroxidation and cytosolic release of CAVIN1 to regulate NRF2	23
Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies	23
Mast cells proliferate in the peri-hippocampal space during early development and modulate local and peripheral immune cells	23
Mammalian autophagosomes form from finger-like phagophores	23
“Fateful” encounter: Lineage tracing meets phylogeny to unravel mysteries of cancer progression	23
Targeted search for scaling genes reveals matrix metalloproteinase 3 as a scaler of the dorsal-ventral pattern in Xenopus laevis embryos	23
A single-cell transcriptomic census of mammalian olfactory epithelium aging	23
Philip N. Benfey (1953–2023)	23
New adventures in spatial transcriptomics	22
Directed cell invasion and asymmetric adhesion drive tissue elongation and turning in C. elegans gonad morphogenesis	22
Extracellular mechanical forces drive endocardial cell volume decrease during zebrafish cardiac valve morphogenesis	22
Functional heterogeneity of Wnt-responsive and Hedgehog-responsive neural stem cells in the murine adult hippocampus	22
Differential growth is an emergent property of mechanochemical feedback mechanisms in curved plant organs	22
Waves of regulated protein expression and phosphorylation rewire the proteome to drive gametogenesis in budding yeast	22
An essential signaling cascade for avian auditory hair cell regeneration	22
NGN3 oscillatory expression controls the timing of human pancreatic endocrine differentiation	22
In vitro generation of mouse morula-like cells	21
Outer mitochondrial membrane E3 Ub ligase MARCH5 controls de novo peroxisome biogenesis	21
The default and directed pathways of hepatoblast differentiation involve distinct epigenomic mechanisms	21
Comparative single-cell multiome identifies evolutionary changes in neural progenitor cells during primate brain development	21
Functional genetic screen identifies ITPR3/calcium/RELB axis as a driver of colorectal cancer metastatic liver colonization	21
Restoration of CPEB4 prevents muscle stem cell senescence during aging	21
Gliotransmission and adenosine signaling promote axon regeneration	21
Tissue-resident macrophages specifically express Lactotransferrin and Vegfc during ear pinna regeneration in spiny mice	21
De novo endocytic clathrin coats develop curvature at early stages of their formation	21
Early human embryonic development: Blastocyst formation to gastrulation	21
Unlocking trophectoderm mysteries: In vivo and in vitro perspectives on human and mouse trophoblast fate induction	21
Transport properties of canonical PIN-FORMED proteins from Arabidopsis and the role of the loop domain in auxin transport	20
Genome-wide analysis of pseudogenes reveals HBBP1’s human-specific essentiality in erythropoiesis and implication in β-thalassemia	20
Eomes restricts Brachyury functions at the onset of mouse gastrulation	20
Single-cell and spatial mapping Identify cell types and signaling Networks in the human ureter	20
Remodeling of cadherin contacts in embryonic mesenchymal tissues during differential cell migration	20
Identifying cross-lineage dependencies of cell-type-specific regulators in mouse gastruloids	20
The spatial zonation of the murine placental vasculature is specified by epigenetic mechanisms	20
Control of murine brown adipocyte development by GATA6	20
Coordinated control of calcium signaling by CPK3 and CaM2 via CNGCs in response to cold stress in Arabidopsis	20
Decreased GATA3 levels cause changed mouse cutaneous innate lymphoid cell fate, facilitating hair follicle recycling	20