Developmental Cell

Papers
(The TQCC of Developmental Cell is 24. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-06-01 to 2024-06-01.)
ArticleCitations
Thriving under Stress: How Plants Balance Growth and the Stress Response320
Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV-2 Receptor ACE2 in the Respiratory Tract316
Phase Separation and Neurodegenerative Diseases: A Disturbance in the Force263
ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation250
Lipid metabolism in cancer: New perspectives and emerging mechanisms228
Phase Separation in Membrane Biology: The Interplay between Membrane-Bound Organelles and Membraneless Condensates194
Distinct contributions of partial and full EMT to breast cancer malignancy183
Single-Cell Sequencing of Developing Human Gut Reveals Transcriptional Links to Childhood Crohn’s Disease179
The Tubulin Code in Microtubule Dynamics and Information Encoding175
Single-Cell RNA Sequencing of Human, Macaque, and Mouse Testes Uncovers Conserved and Divergent Features of Mammalian Spermatogenesis167
ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization163
Quality control of the mitochondrion162
A single-cell analysis of the Arabidopsis vegetative shoot apex157
A Single-Cell Transcriptomic Atlas of Human Skin Aging153
Dietary Lipids Induce Ferroptosis in Caenorhabditiselegans and Human Cancer Cells146
Hematopoietic Stem Cell Metabolism during Development and Aging137
Single-cell RNA sequencing of developing maize ears facilitates functional analysis and trait candidate gene discovery135
Single-cell resolution of lineage trajectories in the Arabidopsis stomatal lineage and developing leaf132
Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex132
CRISPR-Cas13d Induces Efficient mRNA Knockdown in Animal Embryos130
Niches that regulate stem cells and hematopoiesis in adult bone marrow129
Single-Cell Transcriptomic Analyses of the Developing Meninges Reveal Meningeal Fibroblast Diversity and Function123
Cellular Mechanisms and Regulation of Quiescence122
Cancer Cells Don’t Live Alone: Metabolic Communication within Tumor Microenvironments120
Surviving and thriving: How plants perceive and respond to temperature stress120
A single-cell Arabidopsis root atlas reveals developmental trajectories in wild-type and cell identity mutants117
Mechanical Adaptability of Tumor Cells in Metastasis109
NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C109
ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress108
Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies108
Lipid metabolism and lipid signals in aging and longevity106
Intestinal Regeneration: Regulation by the Microenvironment105
Comprehensive Endogenous Tagging of Basement Membrane Components Reveals Dynamic Movement within the Matrix Scaffolding103
The single-cell stereo-seq reveals region-specific cell subtypes and transcriptome profiling in Arabidopsis leaves101
Microtubule Nucleation Properties of Single Human γTuRCs Explained by Their Cryo-EM Structure100
Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival97
Mechanosensing through Direct Binding of Tensed F-Actin by LIM Domains97
Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy95
The GSK3-like Kinase BIN2 Is a Molecular Switch between the Salt Stress Response and Growth Recovery in Arabidopsis thaliana93
Epithelial plasticity, epithelial-mesenchymal transition, and the TGF-β family93
A Dual Protein-mRNA Localization Screen Reveals Compartmentalized Translation and Widespread Co-translational RNA Targeting89
Emerging Roles for Phase Separation in Plants89
Gli1+ Periodontium Stem Cells Are Regulated by Osteocytes and Occlusal Force88
Integration of Hippo-YAP Signaling with Metabolism85
Chromatin Accessibility Dynamics and a Hierarchical Transcriptional Regulatory Network Structure for Plant Somatic Embryogenesis85
Enhancer grammar in development, evolution, and disease: dependencies and interplay84
Metabolites Regulate Cell Signaling and Growth via Covalent Modification of Proteins83
Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells83
S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity83
Liquid-Liquid Phase Separation in Neuronal Development and Synaptic Signaling82
Buckling of an Epithelium Growing under Spherical Confinement81
Autophagy and organelle homeostasis in cancer81
Differentiation of Human Intestinal Organoids with Endogenous Vascular Endothelial Cells81
Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy79
Diverse nitrogen signals activate convergent ROP2-TOR signaling in Arabidopsis78
N6-methyladenosine modification of MALAT1 promotes metastasis via reshaping nuclear speckles78
Tissue mechanics in stem cell fate, development, and cancer78
The Lysosome at the Intersection of Cellular Growth and Destruction77
Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro77
Histone H3 lysine 4 trimethylation in sperm is transmitted to the embryo and associated with diet-induced phenotypes in the offspring76
Mitochondrial-derived vesicles compensate for loss of LC3-mediated mitophagy76
A census of the lung: CellCards from LungMAP76
ER-phagy responses in yeast, plants, and mammalian cells and their crosstalk with UPR and ERAD75
Single-Cell RNA Sequencing of the Cynomolgus Macaque Testis Reveals Conserved Transcriptional Profiles during Mammalian Spermatogenesis73
Dek Modulates Global Intron Retention during Muscle Stem Cells Quiescence Exit73
Next-Generation Lineage Tracing and Fate Mapping to Interrogate Development72
Cell-Cycle-Dependent ERK Signaling Dynamics Direct Fate Specification in the Mammalian Preimplantation Embryo71
Genetic Fate Mapping of Transient Cell Fate Reveals N-Cadherin Activity and Function in Tumor Metastasis71
Live Visualization of ERK Activity in the Mouse Blastocyst Reveals Lineage-Specific Signaling Dynamics70
Extracellular vesicles: Critical players during cell migration69
Fibroblast dedifferentiation as a determinant of successful regeneration69
Early human embryonic development: Blastocyst formation to gastrulation68
Durotaxis: The Hard Path from In Vitro to In Vivo68
Robustness of epithelial sealing is an emerging property of local ERK feedback driven by cell elimination68
Mechanical Coupling Coordinates the Co-elongation of Axial and Paraxial Tissues in Avian Embryos67
The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells67
A BIN2-GLK1 Signaling Module Integrates Brassinosteroid and Light Signaling to Repress Chloroplast Development in the Dark65
Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease64
Spatiotemporal mapping of gene expression landscapes and developmental trajectories during zebrafish embryogenesis64
Mechanics of Development63
Actin-Membrane Release Initiates Cell Protrusions63
An Excitable Ras/PI3K/ERK Signaling Network Controls Migration and Oncogenic Transformation in Epithelial Cells63
Programmable Extracellular Vesicles for Macromolecule Delivery and Genome Modifications62
Global and Site-Specific Effect of Phosphorylation on Protein Turnover62
3D mesenchymal cell migration is driven by anterior cellular contraction that generates an extracellular matrix prestrain62
High-resolution 3D spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae62
Exaptive Evolution of Target of Rapamycin Signaling in Multicellular Eukaryotes61
Inflammation of the Embryonic Choroid Plexus Barrier following Maternal Immune Activation61
Harnessing Mechanobiology for Tissue Engineering61
Excessive R-loops trigger an inflammatory cascade leading to increased HSPC production59
Aging-dependent regulatory cells emerge in subcutaneous fat to inhibit adipogenesis59
A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie–Wnt signaling axis in the liver59
Glutamine Metabolism Controls Chondrocyte Identity and Function57
α-tubulin tail modifications regulate microtubule stability through selective effector recruitment, not changes in intrinsic polymer dynamics57
A human breast atlas integrating single-cell proteomics and transcriptomics56
Subcellular mRNA Localization Regulates Ribosome Biogenesis in Migrating Cells55
Physical properties of the cytoplasm modulate the rates of microtubule polymerization and depolymerization55
Liquid-liquid phase separation of RBGD2/4 is required for heat stress resistance in Arabidopsis55
Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation54
The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth54
Single-cell analysis of human testis aging and correlation with elevated body mass index54
Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongation53
N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation53
Phase Separation in Germ Cells and Development53
Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population53
Diverse Routes toward Early Somites in the Mouse Embryo52
VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites52
WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues51
CDK-Regulated Phase Separation Seeded by Histone Genes Ensures Precise Growth and Function of Histone Locus Bodies51
ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression51
Cholesterol transport between cellular membranes: A balancing act between interconnected lipid fluxes51
Subcellular coordination of plant cell wall synthesis51
Metabolic Communication and Healthy Aging: Where Should We Focus Our Energy?51
Global mapping of glycosylation pathways in human-derived cells51
Selective Lysosome Membrane Turnover Is Induced by Nutrient Starvation50
Metabolic Cellular Communications: Feedback Mechanisms between Membrane Lipid Homeostasis and Plant Development50
A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle50
Membrane receptor-mediated mechano-transduction maintains cell integrity during pollen tube growth within the pistil49
ERK1/2 inhibition promotes robust myotube growth via CaMKII activation resulting in myoblast-to-myotube fusion49
The central moTOR of metabolism49
Modulation of the Promoter Activation Rate Dictates the Transcriptional Response to Graded BMP Signaling Levels in the Drosophila Embryo49
Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production49
Tether Me, Tether Me Not—Dynamic Organelle Contact Sites in Metabolic Rewiring49
Hedgehog Pathway Activation Requires Coreceptor-Catalyzed, Lipid-Dependent Relay of the Sonic Hedgehog Ligand49
A unique macrophage subpopulation signals directly to progenitor cells to promote regenerative neurogenesis in the zebrafish spinal cord48
Caveolae Control Contractile Tension for Epithelia to Eliminate Tumor Cells48
A Weak Link with Actin Organizes Tight Junctions to Control Epithelial Permeability47
Reticulon-3 Promotes Endosome Maturation at ER Membrane Contact Sites47
Lineage-Resolved Enhancer and Promoter Usage during a Time Course of Embryogenesis47
Embryonic Stem Cell-Derived Extracellular Vesicles Maintain ESC Stemness by Activating FAK47
A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase47
Exploring the Influence of Cell Metabolism on Cell Fate through Protein Post-translational Modifications46
Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C46
LIMD1 phase separation contributes to cellular mechanics and durotaxis by regulating focal adhesion dynamics in response to force46
The structure and spontaneous curvature of clathrin lattices at the plasma membrane46
Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage45
Determinants of Endoplasmic Reticulum-to-Lipid Droplet Protein Targeting45
Frizzled-Dependent Planar Cell Polarity without Secreted Wnt Ligands45
DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma45
Glucose starvation induces autophagy via ULK1-mediated activation of PIKfyve in an AMPK-dependent manner44
Formation of polarized contractile interfaces by self-organized Toll-8/Cirl GPCR asymmetry44
RBPMS is an RNA-binding protein that mediates cardiomyocyte binucleation and cardiovascular development44
Genetic variation associated with condensate dysregulation in disease44
Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration43
Genetically variant human pluripotent stem cells selectively eliminate wild-type counterparts through YAP-mediated cell competition43
Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation43
Diversity of developing peripheral glia revealed by single-cell RNA sequencing43
A switch in pdgfrb cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord42
Spatial transcriptional mapping of the human nephrogenic program42
Single-cell transcriptome analysis reveals three sequential phases of gene expression during zebrafish sensory hair cell regeneration42
Compartmentalization of telomeres through DNA-scaffolded phase separation42
Scaling a Dpp Morphogen Gradient through Feedback Control of Receptors and Co-receptors41
Localized EMT reprograms glial progenitors to promote spinal cord repair41
Distinct Cation Gradients Power Cholesterol Transport at Different Key Points in the Hedgehog Signaling Pathway41
Functional Diversification of SRSF Protein Kinase to Control Ubiquitin-Dependent Neurodevelopmental Signaling40
Cell-specific cis-regulatory elements and mechanisms of non-coding genetic disease in human retina and retinal organoids40
The spatiotemporal dynamics of microglia across the human lifespan40
Biomolecular Condensates and Gene Activation in Development and Disease40
Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model40
The Perinuclear ER Scales Nuclear Size Independently of Cell Size in Early Embryos40
Beyond PROX1: transcriptional, epigenetic, and noncoding RNA regulation of lymphatic identity and function39
Messenger RNA 5′ NAD+ Capping Is a Dynamic Regulatory Epitranscriptome Mark That Is Required for Proper Response to Abscisic Acid in Arabidopsis39
Homology-directed repair protects the replicating genome from metabolic assaults39
iPSC-derived myelinoids to study myelin biology of humans38
Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration38
Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates38
Xist Repeats A and B Account for Two Distinct Phases of X Inactivation Establishment38
A reflux-and-growth mechanism explains oscillatory patterning of lateral root branching sites38
A multiscale analysis of early flower development in Arabidopsis provides an integrated view of molecular regulation and growth control37
Oncogene-regulated release of extracellular vesicles37
Rapid Homeostatic Turnover of Embryonic ECM during Tissue Morphogenesis37
Temporal analyses of postnatal liver development and maturation by single-cell transcriptomics37
Inositol Polyphosphate Multikinase Inhibits Liquid-Liquid Phase Separation of TFEB to Negatively Regulate Autophagy Activity37
A Specialized Niche in the Pancreatic Microenvironment Promotes Endocrine Differentiation37
Cardiac proteomics reveals sex chromosome-dependent differences between males and females that arise prior to gonad formation37
Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK36
A Ca2+-sensor switch for tolerance to elevated salt stress in Arabidopsis36
Abscission Couples Cell Division to Embryonic Stem Cell Fate36
Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineages36
Reprogrammed lipid metabolism protects inner nuclear membrane against unsaturated fat35
Combinatorial Action of Temporally Segregated Transcription Factors35
Autophagy promotes cell survival by maintaining NAD levels35
Mechanobiology of the Mitotic Spindle34
Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging34
Metabolic plasticity drives development during mammalian embryogenesis34
An essential role for the piRNA pathway in regulating the ribosomal RNA pool in C. elegans33
FoxA-dependent demethylation of DNA initiates epigenetic memory of cellular identity33
Transient Nodal Signaling in Left Precursors Coordinates Opposed Asymmetries Shaping the Heart Loop33
Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation33
Neuronal mitochondrial dynamics coordinate systemic mitochondrial morphology and stress response to confer pathogen resistance in C. elegans33
Proteostasis failure and mitochondrial dysfunction leads to aneuploidy-induced senescence33
Plant glutamate receptors mediate a bet-hedging strategy between regeneration and defense32
Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration32
Heart regeneration: 20 years of progress and renewed optimism32
Paramecium Polycomb repressive complex 2 physically interacts with the small RNA-binding PIWI protein to repress transposable elements32
Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice32
A potassium-sensing niche in Arabidopsis roots orchestrates signaling and adaptation responses to maintain nutrient homeostasis32
Filopodium-derived vesicles produced by MIM enhance the migration of recipient cells32
Gene regulatory networks shape developmental plasticity of root cell types under water extremes in rice32
Identification of long-lived proteins in the mitochondria reveals increased stability of the electron transport chain32
Phase Separation—A Physical Mechanism for Organizing Information and Biochemical Reactions32
PDGF signaling inhibits mitophagy in glioblastoma stem cells through N-methyladenosine32
Transit-Amplifying Cells Coordinate Changes in Intestinal Epithelial Cell-Type Composition32
Less Is More: Rare Pulmonary Neuroendocrine Cells Function as Critical Sensors in Lung31
Motor usage imprints microtubule stability along the shaft31
Tumor-induced disruption of the blood-brain barrier promotes host death31
Mechanical feedback defines organizing centers to drive digit emergence31
GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis31
Endolysosomal Targeting of Mitochondria Is Integral to BAX-Mediated Mitochondrial Permeabilization during Apoptosis Signaling31
Maintaining the structural and functional homeostasis of the plant endoplasmic reticulum31
The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology30
Oxidative stress pathogenically remodels the cardiac myocyte cytoskeleton via structural alterations to the microtubule lattice30
Rewired glycosylation activity promotes scarless regeneration and functional recovery in spiny mice after complete spinal cord transection30
Coordinate regulation of the senescent state by selective autophagy30
Human placental cytotrophoblast epigenome dynamics over gestation and alterations in placental disease30
Cytoplasm’s Got Moves30
Opposing motors provide mechanical and functional robustness in the human spindle30
Lipid metabolism in adaptation to extreme nutritional challenges29
Cell Junction Mechanics beyond the Bounds of Adhesion and Tension29
Developmental landscape of human forebrain at a single-cell level identifies early waves of oligodendrogenesis29
3D biomimetic platform reveals the first interactions of the embryo and the maternal blood vessels29
Tyramine Acts Downstream of Neuronal XBP-1s to Coordinate Inter-tissue UPRER Activation and Behavior in C. elegans29
Progenitor-like characteristics in a subgroup of UCP1+ cells within white adipose tissue29
PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation29
Mechanistic connections between mitochondrial biology and regulated cell death29
The myogenesis program drives clonal selection and drug resistance in rhabdomyosarcoma29
External Mechanical Cues Reveal a Katanin-Independent Mechanism behind Auxin-Mediated Tissue Bending in Plants28
Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment28
A Mitochondrial Stress-Specific Form of HSF1 Protects against Age-Related Proteostasis Collapse28
A subpopulation of embryonic microglia respond to maternal stress and influence nearby neural progenitors28
PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay28
De novo endocytic clathrin coats develop curvature at early stages of their formation28
Ubiquitin-dependent remodeling of the actin cytoskeleton drives cell fusion28
The Mitotic Crosslinking Protein PRC1 Acts Like a Mechanical Dashpot to Resist Microtubule Sliding28
Adaptable P body physical states differentially regulate bicoid mRNA storage during early Drosophila development27
Mechanical competition triggered by innate immune signaling drives the collective extrusion of bacterially infected epithelial cells27
Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state27
Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling27
piRNAs initiate transcriptional silencing of spermatogenic genes during C. elegans germline development27
Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfβ-Id2 axis, for tissue regeneration27
Transgenerational inheritance of sexual attractiveness via small RNAs enhances evolvability in C. elegans27
Spatiotemporal control of ERK pulse frequency coordinates fate decisions during mammary acinar morphogenesis27
Long-Range Optogenetic Control of Axon Guidance Overcomes Developmental Boundaries and Defects27
Adaptive differentiation promotes intestinal villus recovery26
CREB Non-autonomously Controls Reproductive Aging through Hedgehog/Patched Signaling26
Rheb-regulated mitochondrial pyruvate metabolism of Schwann cells linked to axon stability26
A two-tier junctional mechanism drives simultaneous tissue folding and extension26
The Oncogenic PRL Protein Causes Acid Addiction of Cells by Stimulating Lysosomal Exocytosis26
Vangl2 limits chaperone-mediated autophagy to balance osteogenic differentiation in mesenchymal stem cells26
Phosphorylation of the RecQ Helicase Sgs1/BLM Controls Its DNA Unwinding Activity during Meiosis and Mitosis26
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