Developmental Cell

Papers
(The TQCC of Developmental Cell is 21. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Radially patterned morphogenesis of murine hair follicle placodes ensures robust epithelial budding401
Discrete cis-acting element regulates developmentally timed gene-lamina relocation and neural progenitor competence in vivo257
A transcriptional and regulatory map of mouse somite maturation236
Organoids from pluripotent stem cells and human tissues: When two cultures meet each other221
Therapeutic modulation of GSTO activity rescues FUS-associated neurotoxicity via deglutathionylation in ALS disease models195
cAMP controls a trafficking mechanism that maintains the neuron specificity and subcellular placement of electrical synapses172
Mechanisms of ferroptosis sensitization and resistance161
Mechanics of spindle orientation in human mitotic cells is determined by pulling forces on astral microtubules and clustering of cortical dynein158
TREX1-dependent DNA damage links nuclear rupture to tumor cell invasion150
E3 ubiquitin ligase IPI1 controls rice immunity and flowering via both E3 ligase-dependent and -independent pathways140
Spatial patterning controls neuron numbers in the Drosophila visual system123
CloneSeq: A highly sensitive analysis platform for the characterization of 3D-cultured single-cell-derived clones120
Rim aperture of yeast autophagic membranes balances cargo inclusion with vesicle maturation116
Epithelial cells adapt to curvature induction via transient active osmotic swelling116
Rapid and robust optogenetic control of gene expression in Drosophila109
Maternal and embryonic signals cause functional differentiation of luminal epithelial cells and receptivity establishment109
Diet suppresses glioblastoma initiation in mice by maintaining quiescence of mutation-bearing neural stem cells107
Damage-responsive neuro-glial clusters coordinate the recruitment of dormant neural stem cells in Drosophila106
ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress106
Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients103
Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfβ-Id2 axis, for tissue regeneration102
A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration100
Slc25a3-dependent copper transport controls flickering-induced Opa1 processing for mitochondrial safeguard99
Astrocyte-induced mGluR1 activates human lung cancer brain metastasis via glutamate-dependent stabilization of EGFR97
Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy93
SMARCA5 reprograms AKR1B1-mediated fructose metabolism to control leukemogenesis91
Control of poly(A)-tail length and translation in vertebrate oocytes and early embryos90
Restoration of cone-circuit functionality in the regenerating adult zebrafish retina89
A human breast atlas integrating single-cell proteomics and transcriptomics86
HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function85
Epithelial tissue confinement inhibits cell growth and leads to volume-reducing divisions85
Partial closure of the γ-tubulin ring complex by CDK5RAP2 activates microtubule nucleation84
Adaptive mechanoproperties mediated by the formin FMN1 characterize glioblastoma fitness for invasion79
Stepping on the molecular brake: Slowing down proliferation to allow differentiation79
KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling77
YAP1 and PRDM14 converge to promote cell survival and tumorigenesis76
Genetic variation associated with condensate dysregulation in disease75
The endophilin curvature-sensitive motif requires electrostatic guidance to recycle synaptic vesicles in vivo74
Nucleolar protein PEXF controls ribosomal RNA synthesis and pluripotency exit72
A condensates-to-VPS41-associated phagic vacuoles conversion pathway controls autophagy degradation in plants71
BMP-gated cell-cycle progression drives anoikis during mesenchymal collective migration70
Seamless knockins in Drosophila via CRISPR-triggered single-strand annealing70
Pollen-stigma incompatibility within and between species: Tread lightly, sedate the dogs, and don’t wake the guards!69
Can’t smell the virus: SARS-CoV-2, chromatin organization, and anosmia65
Differential compartmentalization of BMP4/NOGGIN requires NOGGIN trans-epithelial transport65
Bidirectional activation of stem-like programs between metastatic cancer and alveolar type 2 cells within the niche64
Neuronal-epithelial cross-talk drives acinar specification via NRG1-ERBB3-mTORC2 signaling63
Lysosomal catabolic activity promotes the exit of murine totipotent 2-cell state by silencing early-embryonic retrotransposons63
Distinct classes of lagging chromosome underpin age-related oocyte aneuploidy in mouse62
MAP9/MAPH-9 supports axonemal microtubule doublets and modulates motor movement62
SUMO style defense: How post-translational modification via SUMO conjugation promotes plant defense62
How structural interactions and receptor phosphorylation shape strigolactone signaling in rice62
Vimentin intermediate filaments coordinate actin stress fibers and podosomes to determine the extracellular matrix degradation by macrophages61
Traveling to the left: A story of PKD1L1-containing vesicles61
Don’t fear the reaper: The role of regulated cell death in tumorigenesis and BH3-mimetics for cancer therapy59
Nuclear receptor Nr5a2 promotes diverse connective tissue fates in the jaw59
Axon guidance in central nervous system regeneration57
SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway56
The microtubular preprophase band recruits Myosin XI to the cortical division site to guide phragmoplast expansion during plant cytokinesis56
Nitric oxide controls stomatal development and stress responses by inhibiting MPK6 phosphorylation via S-nitrosylation in Arabidopsis55
Interaction between Ras and Src clones causes interdependent tumor malignancy via Notch signaling in Drosophila55
Dynamic control of H2A.Zub and H3K27me3 by ambient temperature during cell fate determination in Arabidopsis55
Tumor-derived MMPs regulate cachexia in a Drosophila cancer model55
An Oatp transporter-mediated steroid sink promotes tumor-induced cachexia in Drosophila54
Human yolk sac-derived innate lymphoid-biased multipotent progenitors emerge prior to hematopoietic stem cell formation53
Fibrous periosteum repairs bone fracture and maintains the healed bone throughout mouse adulthood53
Xyloglucan side chains enable polysaccharide secretion to the plant cell wall53
Spatiotemporal mapping of gene expression landscapes and developmental trajectories during zebrafish embryogenesis53
Mechanical regulation of substrate adhesion and de-adhesion drives a cell-contractile wave during Drosophila tissue morphogenesis52
Mannose controls mesoderm specification and symmetry breaking in mouse gastruloids52
CLMP is a tumor suppressor that determines all-trans retinoic acid response in colorectal cancer52
The miR-430 locus with extreme promoter density forms a transcription body during the minor wave of zygotic genome activation52
20 years of Developmental Cell: Looking forward52
Adhesion tunes speed and persistence by coordinating protrusions and extracellular matrix remodeling51
Localized glucose import, glycolytic processing, and mitochondria generate a focused ATP burst to power basement-membrane invasion50
Transgenesis in the acoel worm Hofstenia miamia49
The BAS chromatin remodeler determines brassinosteroid-induced transcriptional activation and plant growth in Arabidopsis49
Extracellular matrix assembly stress initiates Drosophila central nervous system morphogenesis49
Pten, PI3K, and PtdIns(3,4,5)P3 dynamics control pulsatile actin branching in Drosophila retina morphogenesis48
Immune mechanisms shape the clonal landscape during early progression of prostate cancer48
Mesodermal fibronectin controls cell shape, polarity, and mechanotransduction in the second heart field during cardiac outflow tract development47
Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation47
Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis47
Vasculature is getting Hip(po): Hippo signaling in vascular development and disease47
TDRD1 phase separation drives intermitochondrial cement assembly to promote piRNA biogenesis and fertility47
Allelic transcriptomic profiling identifies the role of PRD-like homeobox genes in human embryonic-cleavage-stage arrest47
Chromatin remodeling of prostaglandin signaling in smooth muscle enables mouse embryo passage through the female reproductive tract47
Endosomal trafficking and DNA damage checkpoint kinases dictate survival to replication stress by regulating amino acid uptake and protein synthesis46
Spatially resolved proteomics of the Arabidopsis stomatal lineage identifies polarity complexes for cell divisions and stomatal pores46
S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity46
Optogenetic manipulation identifies the roles of ERK and AKT dynamics in controlling mouse embryonic stem cell exit from pluripotency46
Plant glutamate receptors mediate a bet-hedging strategy between regeneration and defense46
VAMP2 controls murine epidermal differentiation and carcinogenesis by regulation of nucleophagy45
Separase cleaves the kinetochore protein Meikin at the meiosis I/II transition45
Developmental landscape of human forebrain at a single-cell level identifies early waves of oligodendrogenesis45
Smooth muscle contributes to the development and function of a layered intestinal stem cell niche45
Seriously cilia: A tiny organelle illuminates evolution, disease, and intercellular communication45
Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method45
Integrated transcriptomics of human blood vessels defines a spatially controlled niche for early mesenchymal progenitor cells44
Bending toward differentiation44
Monomethyl branched-chain fatty acid mediates amino acid sensing upstream of mTORC143
Understanding the cell fate and behavior of progenitors at the origin of the mouse cardiac mitral valve43
Assembly of tight junction belts by ZO1 surface condensation and local actin polymerization43
ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells43
GLRs: Mediating a defense-regeneration tradeoff in plants42
A single-cell census of mouse limb development identifies complex spatiotemporal dynamics of skeleton formation42
Combined kinesin-1 and kinesin-3 activity drives axonal trafficking of TrkB receptors in Rab6 carriers42
RNA N6-methyladenosine modification promotes auxin biosynthesis required for male meiosis in rice42
Septins regulate border cell surface geometry, shape, and motility downstream of Rho in Drosophila42
Distinct p53 isoforms code for opposing transcriptional outcomes42
Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging42
Sweat gland development requires an eccrine dermal niche and couples two epidermal programs41
20 years of Developmental Cell: Looking back41
Polyploid mitosis and depolyploidization promote chromosomal instability and tumor progression in a Notch-induced tumor model40
Decoding the organization, dynamics, and function of the 4D genome40
Extracellular carriers control lipid-dependent secretion, delivery, and activity of WNT morphogens40
Identification of Greb1l as a genetic determinant of crisscross heart in mice showing torsion of the heart tube by shortage of progenitor cells39
Integration of vascular progenitors into functional blood vessels represents a distinct mechanism of vascular growth39
ZINC FINGER PROTEIN2 suppresses funiculus lignification to ensure seed loading efficiency in Arabidopsis38
Collective oscillatory signaling in Dictyostelium discoideum acts as a developmental timer initiated by weak coupling of a noisy pulsatile signal38
Developmental angiocrine diversification of endothelial cells for organotypic regeneration38
Mitochondrial GTP metabolism controls reproductive aging in C. elegans38
Formation of polarized contractile interfaces by self-organized Toll-8/Cirl GPCR asymmetry37
A translation control module coordinates germline stem cell differentiation with ribosome biogenesis during Drosophila oogenesis37
Spatial transcriptional mapping of the human nephrogenic program37
Lipid metabolism and lipid signals in aging and longevity36
Actomyosin contractility in olfactory placode neurons opens the skin epithelium to form the zebrafish nostril36
Deceleration of the cell cycle underpins a switch from proliferative to terminal divisions in plant stomatal lineage36
Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells36
Metabolic plasticity drives development during mammalian embryogenesis36
Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongation36
Microenvironmental innate immune signaling and cell mechanical responses promote tumor growth36
Vangl2 limits chaperone-mediated autophagy to balance osteogenic differentiation in mesenchymal stem cells36
ZNFX-1 keeps RNAi in the loop35
A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase35
Activity-dependent local protection and lateral inhibition control synaptic competition in developing mitral cells in mice35
ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer34
Building a kidney tree: Functional collecting duct from human pluripotent stem cells34
Toll receptors remodel epithelia by directing planar-polarized Src and PI3K activity34
Wnt signaling couples G2 phase control with differentiation during hematopoiesis in Drosophila34
Quantitative proteomic profiling identifies global protein network dynamics in murine embryonic heart development34
Persistent cell contacts enable E-cadherin/HMR-1- and PAR-3-based symmetry breaking within a developing C. elegans epithelium34
A Scribble/Cdep/Rac pathway controls follower-cell crawling and cluster cohesion during collective border-cell migration34
Mapping the dynamics of epigenetic adaptation in S. pombe during heterochromatin misregulation34
Detection of surface forces by the cell-wall mechanosensor Wsc1 in yeast33
Antagonistic systemin receptors integrate the activation and attenuation of systemic wound signaling in tomato33
Gene module reconstruction identifies cellular differentiation processes and the regulatory logic of specialized secretion in zebrafish33
An exception to the rule? Regeneration of the injured spinal cord in the spiny mouse33
Asymmetric partitioning of persistent paternal mitochondria during cell divisions safeguards embryo development and mitochondrial inheritance33
Hepatocytic lipocalin-2 controls HDL metabolism and atherosclerosis via Nedd4-1-SR-BI axis in mice33
In the mouse cortex, oligodendrocytes regain a plastic capacity, transforming into astrocytes after acute injury32
Aging-induced changes in lymphatic muscle cell transcriptomes are associated with reduced pumping of peripheral collecting lymphatic vessels in mice32
A subset of neutrophils activates anti-tumor immunity and inhibits non-small-cell lung cancer progression32
PITTching in for lysosome repair32
Fate mapping in mouse demonstrates early secretory differentiation directly from Lgr5+ intestinal stem cells32
Cell death: Revisiting the roads to ruin32
Morphogenesis and regeneration share a conserved core transition cell state program that controls lung epithelial cell fate32
Notochord segmentation in zebrafish controlled by iterative mechanical signaling32
4D reconstruction of murine developmental trajectories using spherical harmonics31
Long noncoding RNA ARTA controls ABA response through MYB7 nuclear trafficking in Arabidopsis31
Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster31
YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth31
Dual states of murine Bmi1-expressing intestinal stem cells drive epithelial development utilizing non-canonical Wnt signaling30
Mechanistic connections between mitochondrial biology and regulated cell death30
The Hitchhiker’s Guide across a Waddington’s landscape of melanoma30
Force-dependent activation of actin elongation factor mDia1 protects the cytoskeleton from mechanical damage and promotes stress fiber repair30
Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival29
Oncogene-regulated release of extracellular vesicles29
Molecular and spatial landmarks of early mouse skin development29
Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration29
A chromatin code for limb segment identity in axolotl limb regeneration29
Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation29
Evolutionarily conserved midbody remodeling precedes ring canal formation during gametogenesis29
SigmaR1 shapes rough endoplasmic reticulum membrane sheets28
Inherited nuclear pore substructures template post-mitotic pore assembly28
Controlling pyroptosis through post-translational modifications of gasdermin D28
An unexpected puzzle piece links polarity and chromosome segregation28
Mending microtubules enhances cell polarity28
An integrated approach identifies the molecular underpinnings of murine anterior visceral endoderm migration28
TaANK-TPR1 enhances wheat resistance against stripe rust via controlling gene expression and protein activity of NLR protein TaRPP13L128
How meningeal macrophages control medulloblastoma induction28
Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover27
EYA protein complex is required for Wntless retrograde trafficking from endosomes to Golgi27
The mechanical state of pre-tumoral epithelia controls subsequent Drosophila tumor aggressiveness27
ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion27
iPSC-derived myelinoids to study myelin biology of humans27
Glutamine-dependent signaling controls pluripotent stem cell fate27
Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD27
Single-cell chromatin accessibility identifies enhancer networks driving gene expression during spinal cord development in mouse27
DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice27
Self-extinguishing relay waves enable homeostatic control of human neutrophil swarming27
Microtubule-associated protein MAP7 promotes tubulin posttranslational modifications and cargo transport to enable osmotic adaptation27
Reshaping of the tumor microenvironment by cellular senescence: An opportunity for senotherapies27
Lineage-tracing hematopoietic stem cell origins in vivo to efficiently make human HLF+ HOXA+ hematopoietic progenitors from pluripotent stem cells27
Giving translation a hand26
The elusive pulmonary neuroendocrine cell: How rare diseases may help solving common diseases26
A limb bud morphogen bites the dust26
FANCI functions as a repair/apoptosis switch in response to DNA crosslinks26
Meningeal macrophages inhibit chemokine signaling in pre-tumor cells to suppress mouse medulloblastoma initiation26
Targeted search for scaling genes reveals matrix metalloproteinase 3 as a scaler of the dorsal-ventral pattern in Xenopus laevis embryos26
From nuclear to extracellular PTEN: Multiple roles in tumor suppression and immune modulation26
Ubiquitin ligase MARCH5 controls the formation of mitochondria-derived pre-peroxisomes25
A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression25
Differential condensation of sister chromatids acts with Cdc6 to ensure asynchronous S-phase entry in Drosophila male germline stem cell lineage25
H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity25
DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential25
Regulation of reverse electron transfer at mitochondrial complex I by unconventional Notch action in cancer stem cells25
An SLC12A9-dependent ion transport mechanism maintains lysosomal osmolarity25
Identification of a non-canonical planar cell polarity pathway triggered by light in the developing mouse retina25
Mammalian autophagosomes form from finger-like phagophores25
Kinetochore life histories reveal an Aurora-B-dependent error correction mechanism in anaphase25
A single-cell transcriptomic census of mammalian olfactory epithelium aging25
Mast cells proliferate in the peri-hippocampal space during early development and modulate local and peripheral immune cells25
Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon24
Endoplasmic reticulum exit sites are segregated for secretion based on cargo size24
Plasticity in airway smooth muscle differentiation during mouse lung development24
Heart regeneration: 20 years of progress and renewed optimism24
Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye24
Caveolae sense oxidative stress through membrane lipid peroxidation and cytosolic release of CAVIN1 to regulate NRF224
Acute brain vascular regeneration occurs via lymphatic transdifferentiation24
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility24
RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness24
Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation24
The Drosophila adult midgut progenitor cells arise from asymmetric divisions of neuroblast-like cells24
New adventures in spatial transcriptomics23
Outer mitochondrial membrane E3 Ub ligase MARCH5 controls de novo peroxisome biogenesis23
Philip N. Benfey (1953–2023)23
Functional genetic screen identifies ITPR3/calcium/RELB axis as a driver of colorectal cancer metastatic liver colonization23
Comparative single-cell multiome identifies evolutionary changes in neural progenitor cells during primate brain development23
Lewis Wolpert (1929–2021)23
Decreased GATA3 levels cause changed mouse cutaneous innate lymphoid cell fate, facilitating hair follicle recycling23
Identifying cross-lineage dependencies of cell-type-specific regulators in mouse gastruloids23
The spatial zonation of the murine placental vasculature is specified by epigenetic mechanisms23
Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies23
“Fateful” encounter: Lineage tracing meets phylogeny to unravel mysteries of cancer progression23
Control of murine brown adipocyte development by GATA623
The default and directed pathways of hepatoblast differentiation involve distinct epigenomic mechanisms23
Eomes restricts Brachyury functions at the onset of mouse gastrulation22
Restoration of CPEB4 prevents muscle stem cell senescence during aging22
Functional heterogeneity of Wnt-responsive and Hedgehog-responsive neural stem cells in the murine adult hippocampus22
Directed cell invasion and asymmetric adhesion drive tissue elongation and turning in C. elegans gonad morphogenesis22
Extracellular mechanical forces drive endocardial cell volume decrease during zebrafish cardiac valve morphogenesis22
Synthetic Notch receptors and their applications to study cell-cell contacts in vivo22
Differential growth is an emergent property of mechanochemical feedback mechanisms in curved plant organs22
Modeling myelin: A toolkit for exploring myelin’s mysteries in vitro22
De novo endocytic clathrin coats develop curvature at early stages of their formation22
Single-cell and spatial mapping Identify cell types and signaling Networks in the human ureter22
Transport properties of canonical PIN-FORMED proteins from Arabidopsis and the role of the loop domain in auxin transport22
A morphogenetic wave in the chick embryo lateral mesoderm generates mesenchymal-epithelial transition through a 3D-rosette intermediate22
In vitro generation of mouse morula-like cells21
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