Developmental Cell

Papers
(The TQCC of Developmental Cell is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)
ArticleCitations
Breaking new ground: Decoding the root’s molecular circuits to penetrate compacted soil325
Disruption of H3K36 methylation provokes cellular plasticity to drive aberrant glandular formation and squamous carcinogenesis278
An SLC12A9-dependent ion transport mechanism maintains lysosomal osmolarity234
Gut microbiota protect against colorectal tumorigenesis through lncRNA Snhg9230
Slow muscles guide fast myocyte fusion to ensure robust myotome formation despite the high spatiotemporal stochasticity of fusion events191
Endothelial and Leptin Receptor+ cells promote the maintenance of stem cells and hematopoiesis in early postnatal murine bone marrow185
Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages182
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility164
Autophagy Blockade Limits HER2+ Breast Cancer Tumorigenesis by Perturbing HER2 Trafficking and Promoting Release Via Small Extracellular Vesicles153
Endoplasmic reticulum exit sites are segregated for secretion based on cargo size152
Apical polarity and actomyosin dynamics control Kibra subcellular localization and function in Drosophila Hippo signaling152
Regulation of reverse electron transfer at mitochondrial complex I by unconventional Notch action in cancer stem cells147
Giving translation a hand139
YAP—deLIVERing the directions and the fuel136
A mechanism to PLAse the eye131
Cell geometry, signal dampening, and a bimodal transcriptional response underlie the spatial precision of an ERK-mediated embryonic induction127
Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon119
AGO1 controls protein folding in mouse embryonic stem cell fate decisions118
Is developmental synchrony enabled by CTCF residence time?110
Targeted search for scaling genes reveals matrix metalloproteinase 3 as a scaler of the dorsal-ventral pattern in Xenopus laevis embryos106
Mechanical instability of adherens junctions overrides intrinsic quiescence of hair follicle stem cells100
Soaping up transcriptional condensates98
A single-cell transcriptomic map of the developing Atoh1 lineage identifies neural fate decisions and neuronal diversity in the hindbrain92
Restoration of cone-circuit functionality in the regenerating adult zebrafish retina91
Soybean symbiotic-nodule zonation and cell differentiation are defined by NIN2 signaling and GH3-dependent auxin homeostasis89
cAMP controls a trafficking mechanism that maintains the neuron specificity and subcellular placement of electrical synapses88
A cellular hierarchy of Notch and Kras signaling controls cell fate specification in the developing mouse salivary gland87
SALSA, a genetically encoded biosensor for spatiotemporal quantification of Notch signal transduction in vivo86
Guidance by followers ensures long-range coordination of cell migration through α-catenin mechanoperception86
Damage-responsive neuro-glial clusters coordinate the recruitment of dormant neural stem cells in Drosophila85
Epithelial cells adapt to curvature induction via transient active osmotic swelling84
VAB-8 stops dynein in its tracks to regulate synaptic delivery83
Tracing embryonic hematopoiesis guides induction of pluripotent stem cells to hematopoietic progenitors83
Spatial patterning controls neuron numbers in the Drosophila visual system81
A temporal allocation of amino acid resources ensures fitness and body allometry in Drosophila80
The elusive pulmonary neuroendocrine cell: How rare diseases may help solving common diseases80
Epigenetic reprogramming enables NF1A/B oncogenic role in SHH medulloblastoma79
DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential79
Therapeutic modulation of GSTO activity rescues FUS-associated neurotoxicity via deglutathionylation in ALS disease models77
Excess neuropeptides in lung signal through endothelial cells to impair gas exchange76
Defining a TFAP2C-centered transcription factor network during murine peri-implantation76
A leucine-derived fatty acid unlocks the mTOR to development73
Beyond PROX1: transcriptional, epigenetic, and noncoding RNA regulation of lymphatic identity and function72
Clone competition as a mechanism to reduce tumor formation71
TREX1-dependent DNA damage links nuclear rupture to tumor cell invasion68
Characterization of the human fetal gonad and reproductive tract by single-cell transcriptomics67
The developing murine kidney actively negotiates geometric packing conflicts to avoid defects67
FANCI functions as a repair/apoptosis switch in response to DNA crosslinks67
Differential condensation of sister chromatids acts with Cdc6 to ensure asynchronous S-phase entry in Drosophila male germline stem cell lineage65
Changes in nuclear pore numbers control nuclear import and stress response of mouse hearts64
An amino acid-resolution interactome for motile cilia identifies the structure and function of ciliopathy protein complexes63
Identification of a non-canonical planar cell polarity pathway triggered by light in the developing mouse retina63
Human embryonic and fetal biobanking: Establishing the Dutch Fetal Biobank and a framework for standardization62
Rim aperture of yeast autophagic membranes balances cargo inclusion with vesicle maturation61
Radially patterned morphogenesis of murine hair follicle placodes ensures robust epithelial budding61
Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients60
Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy59
Liquid-liquid phase separation of RBGD2/4 is required for heat stress resistance in Arabidopsis59
Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies59
The evolutionarily conserved arginyltransferase 1 mediates a pVHL-independent oxygen-sensing pathway in mammalian cells58
Discrete cis-acting element regulates developmentally timed gene-lamina relocation and neural progenitor competence in vivo56
NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C56
Astrocyte-induced mGluR1 activates human lung cancer brain metastasis via glutamate-dependent stabilization of EGFR55
Control of poly(A)-tail length and translation in vertebrate oocytes and early embryos55
May the force be with you: Mechanosensitivity shapes dendrite development54
A limb bud morphogen bites the dust54
Plasticity in airway smooth muscle differentiation during mouse lung development54
Improving stem cell-derived pancreatic islets using single-cell multi-inferred regulomes53
Identification of signaling pathways that specify a subset of migrating enteric neural crest cells at the wavefront in mouse embryos52
Lysosomes to the rescue: Anterograde axonal lysosome transport and neuronal proteostasis52
Shedding light on stem cells: Optogenetics uncover the role of ERK dynamics in pluripotency52
Mammalian autophagosomes form from finger-like phagophores52
Epithelial UNC-23 limits mechanical stress to maintain glia-neuron architecture in C. elegans51
The membrane surface as a platform that organizes cellular and biochemical processes51
SMARCA5 reprograms AKR1B1-mediated fructose metabolism to control leukemogenesis50
Single-cell omics identifies inflammatory signaling as a trans-differentiation trigger in mouse embryos50
Tumor-induced disruption of the blood-brain barrier promotes host death49
Variability of cross-tissue X-chromosome inactivation characterizes timing of human embryonic lineage specification events49
Transcription factor induction of vascular blood stem cell niches in vivo49
Autophagy supports PDGFRA-dependent brain tumor development by enhancing oncogenic signaling49
Myosin waves and a mechanical asymmetry guide the oscillatory migration of Drosophila cardiac progenitors49
Consumption of a polarized membrane reservoir drives asymmetric membrane expansion during the unequal divisions of neural stem cells48
CloneSeq: A highly sensitive analysis platform for the characterization of 3D-cultured single-cell-derived clones47
scRNA-seq data from the larval Drosophila ventral cord provides a resource for studying motor systems function and development46
Apoptotic extracellular vesicle formation via local phosphatidylserine exposure drives efficient cell extrusion46
Maternal and embryonic signals cause functional differentiation of luminal epithelial cells and receptivity establishment45
Nuclear import carrier Hikeshi cooperates with HSP70 to promote murine oligodendrocyte differentiation and CNS myelination45
Comparative single-cell analyses identify shared and divergent features of human and mouse kidney development45
A single-cell transcriptomic census of mammalian olfactory epithelium aging44
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome44
An E-cadherin-actin clutch translates the mechanical force of cortical flow for cell-cell contact to inhibit epithelial cell locomotion44
Two sides of the Dlk1-Dio3 story in imprinting43
Rejection of inappropriate synaptic partners in mouse retina mediated by transcellular FLRT2-UNC5 signaling43
A tubule-sheet continuum model for the mechanism of nuclear envelope assembly43
Optimizing rice grain size by attenuating phosphorylation-triggered functional impairment of a chromatin modifier ternary complex42
Paracellular transport: Opening the gates for growth42
Mauve/LYST limits fusion of lysosome-related organelles and promotes centrosomal recruitment of microtubule nucleating proteins42
An evolutionarily conserved mechanism controls reversible amyloids of pyruvate kinase via pH-sensing regions42
Negative elongation factor regulates muscle progenitor expansion for efficient myofiber repair and stem cell pool repopulation42
E3 ubiquitin ligase IPI1 controls rice immunity and flowering via both E3 ligase-dependent and -independent pathways41
A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration41
Itaconate uptake via SLC13A3 improves hepatic antibacterial innate immunity41
Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state40
The central moTOR of metabolism40
HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function40
The p-rpS6-zone delineates wounding responses and the healing process40
Surviving and thriving: How plants perceive and respond to temperature stress40
Temporal regulation of vegetative phase change in plants39
Pyruvate modulation of redox potential controls mouse sperm motility39
Slc25a3-dependent copper transport controls flickering-induced Opa1 processing for mitochondrial safeguard38
Age-associated interplay between zinc deficiency and Golgi stress hinders microtubule-dependent cellular signaling and epigenetic control38
Reconstitution of human adrenocortical specification and steroidogenesis using induced pluripotent stem cells37
PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay37
3D mesenchymal cell migration is driven by anterior cellular contraction that generates an extracellular matrix prestrain37
Filopodium-derived vesicles produced by MIM enhance the migration of recipient cells37
Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation37
Peripheral but critical: Translation of germ granule mRNAs in zebrafish37
RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness37
Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfβ-Id2 axis, for tissue regeneration37
Response to Matters Arising: Intercellular genetic tracing of cardiac endothelium in the developing heart37
A human breast atlas integrating single-cell proteomics and transcriptomics37
SRSF1 governs progenitor-specific alternative splicing to maintain adult epithelial tissue homeostasis and renewal36
Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells36
Diet suppresses glioblastoma initiation in mice by maintaining quiescence of mutation-bearing neural stem cells35
ER-phagy responses in yeast, plants, and mammalian cells and their crosstalk with UPR and ERAD35
Heart regeneration: 20 years of progress and renewed optimism35
α-tubulin tail modifications regulate microtubule stability through selective effector recruitment, not changes in intrinsic polymer dynamics35
Acute brain vascular regeneration occurs via lymphatic transdifferentiation35
Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye35
PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport34
Rapid and robust optogenetic control of gene expression in Drosophila34
VAP-A intrinsically disordered regions enable versatile tethering at membrane contact sites34
H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity34
Caveolae sense oxidative stress through membrane lipid peroxidation and cytosolic release of CAVIN1 to regulate NRF233
Laying out the mammalian body plan to a T33
Epithelial tissue confinement inhibits cell growth and leads to volume-reducing divisions32
A single-cell Arabidopsis root atlas reveals developmental trajectories in wild-type and cell identity mutants32
Mechanical pressure-induced dedifferentiation of myofibroblasts inhibits scarring via SMYD3/ITGBL1 signaling32
T cell cytoskeletal forces shape synapse topography for targeted lysis via membrane curvature bias of perforin32
Actuation of single downstream nodes in growth factor network steers immune cell migration32
The Polycomb group protein MEDEA controls cell proliferation and embryonic patterning in Arabidopsis31
A Ca2+-sensor switch for tolerance to elevated salt stress in Arabidopsis31
Single-cell analysis of human testis aging and correlation with elevated body mass index31
Low-density-lipoprotein-receptor-related protein 1 mediates Notch pathway activation31
RBPMS is an RNA-binding protein that mediates cardiomyocyte binucleation and cardiovascular development31
PDGF signaling inhibits mitophagy in glioblastoma stem cells through N-methyladenosine31
LIMD1 phase separation contributes to cellular mechanics and durotaxis by regulating focal adhesion dynamics in response to force31
A transcriptional and regulatory map of mouse somite maturation31
Epithelial plasticity, epithelial-mesenchymal transition, and the TGF-β family31
Kinetochore life histories reveal an Aurora-B-dependent error correction mechanism in anaphase30
Microvilli control the morphogenesis of the tectorial membrane extracellular matrix30
Dual function of PHF16 in reinstating homeostasis of murine intestinal epithelium after crypt regeneration30
Partial closure of the γ-tubulin ring complex by CDK5RAP2 activates microtubule nucleation30
A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression30
A Single-Cell Transcriptomic Atlas of Human Skin Aging30
From nuclear to extracellular PTEN: Multiple roles in tumor suppression and immune modulation30
ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress30
Spatiotemporal dynamics of the developing zebrafish enteric nervous system at the whole-organ level29
Mast cells proliferate in the peri-hippocampal space during early development and modulate local and peripheral immune cells29
Mechanics of spindle orientation in human mitotic cells is determined by pulling forces on astral microtubules and clustering of cortical dynein29
Tao and Rap2l ensure proper Misshapen activation and levels during Drosophila border cell migration29
The Drosophila adult midgut progenitor cells arise from asymmetric divisions of neuroblast-like cells29
Single-nucleus sequencing deciphers developmental trajectories in rice pistils29
Ubiquitin ligase MARCH5 controls the formation of mitochondria-derived pre-peroxisomes29
Proteolysis-free amoeboid migration of melanoma cells through crowded environments via bleb-driven worrying29
Modeling myelin: A toolkit for exploring myelin’s mysteries in vitro28
The UBE2F-CRL5ASB11-DIRAS2 axis is an oncogene and tumor suppressor cascade in pancreatic cancer cells28
Stir it up: The role of actin in mitochondrial mixing during mitosis28
Traveling to the left: A story of PKD1L1-containing vesicles28
SURF4-induced tubular ERGIC selectively expedites ER-to-Golgi transport28
Differential compartmentalization of BMP4/NOGGIN requires NOGGIN trans-epithelial transport28
How NPC1 Loss Twists the TORCque of Lysosomes28
The endophilin curvature-sensitive motif requires electrostatic guidance to recycle synaptic vesicles in vivo28
MDVs to the rescue: How autophagy-deficient cancer cells adapt to defective mitophagy28
Fibrous periosteum repairs bone fracture and maintains the healed bone throughout mouse adulthood28
Stepping on the molecular brake: Slowing down proliferation to allow differentiation27
Telomere dysfunction alters intestinal stem cell dynamics to promote cancer27
CDK4: Linking cell size to cell cycle control27
3D reconstruction of the mouse cochlea from scRNA-seq data suggests morphogen-based principles in apex-to-base specification27
Decoding anterior-posterior axis emergence among mouse, monkey, and human embryos26
Seamless knockins in Drosophila via CRISPR-triggered single-strand annealing26
Skin-type-dependent development of murine mechanosensory neurons26
The sirtuin-associated human senescence program converges on the activation of placenta-specific gene PAPPA26
ER-Golgi-localized proteins TMED2 and TMED10 control the formation of plasma membrane lipid nanodomains26
YAP1 and PRDM14 converge to promote cell survival and tumorigenesis26
Vangl-dependent mesenchymal thinning shapes the distal lung during murine sacculation26
Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK26
Synthetic Notch receptors and their applications to study cell-cell contacts in vivo25
Glucose starvation induces autophagy via ULK1-mediated activation of PIKfyve in an AMPK-dependent manner25
Nucleolar protein PEXF controls ribosomal RNA synthesis and pluripotency exit25
Eomes restricts Brachyury functions at the onset of mouse gastrulation25
Early human embryonic development: Blastocyst formation to gastrulation25
The miR-430 locus with extreme promoter density forms a transcription body during the minor wave of zygotic genome activation25
HMOX1-LDHB interaction promotes ferroptosis by inducing mitochondrial dysfunction in foamy macrophages during advanced atherosclerosis24
New adventures in spatial transcriptomics24
An ILK/STAT3 pathway controls glioblastoma stem cell plasticity24
SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway24
Differential growth is an emergent property of mechanochemical feedback mechanisms in curved plant organs24
Multimodal mass spectrometry imaging identifies cell-type-specific metabolic and lipidomic variation in the mammalian liver24
Single-cell analysis of shared signatures and transcriptional diversity during zebrafish development24
A junction-dependent mechanism drives murine mammary cell intercalation for ductal elongation24
Progenitor-like characteristics in a subgroup of UCP1+ cells within white adipose tissue23
Pollen-stigma incompatibility within and between species: Tread lightly, sedate the dogs, and don’t wake the guards!23
Shaping the heart with mechanosensitive shrinking cells23
A functional circuit formed by the autonomic nerves and myofibroblasts controls mammalian alveolar formation for gas exchange23
A twist in Pitx2 regulation of gut looping23
Construction of single-cell cross-species chromatin accessibility landscapes with combinatorial-hybridization-based ATAC-seq23
Single-cell RNA sequencing of developing maize ears facilitates functional analysis and trait candidate gene discovery23
From friend to foe: Pro-apoptotic action of nuclear ARC in diabetes23
Girl power: NORTIA polarization seals pollen tube fate23
Oct4 controls basement membrane development during human embryogenesis23
“Fateful” encounter: Lineage tracing meets phylogeny to unravel mysteries of cancer progression23
Autophagy and organelle homeostasis in cancer23
FoxA-dependent demethylation of DNA initiates epigenetic memory of cellular identity23
Genome-wide analysis of pseudogenes reveals HBBP1’s human-specific essentiality in erythropoiesis and implication in β-thalassemia23
Working together: Heterotypic clusters and collective cell migration in melanoma metastasis23
Lewis Wolpert (1929–2021)23
Can’t smell the virus: SARS-CoV-2, chromatin organization, and anosmia23
KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling23
Diverse nitrogen signals activate convergent ROP2-TOR signaling in Arabidopsis23
Losing the license to regenerate hair cells22
Initiation and maintenance of the pluripotent epiblast in pre-implantation human development is independent of NODAL signaling22
Ribosomal RNA 2′-O-methylation dynamics impact cell fate decisions22
Feeling the pressure: A mechanical tale of the pollen tube journey through the pistil22
Calcium-dependent protein kinases CPK3/4/6/11 and 27 respond to osmotic stress and activate SnRK2s in Arabidopsis22
Breaking down barriers: Tumors make a leaky brain22
GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis22
Ataxin-2 polyglutamine expansions aberrantly sequester TDP-43 ribonucleoprotein condensates disrupting mRNA transport and local translation in neurons22
The spatial zonation of the murine placental vasculature is specified by epigenetic mechanisms21
Multimodal screen identifies noise-regulatory proteins21
Accelerated cell cycles enable organ regeneration under developmental time constraints in the Drosophila hindgut21
Angiomotin cleavage promotes leader formation and collective cell migration21
Outer mitochondrial membrane E3 Ub ligase MARCH5 controls de novo peroxisome biogenesis21
DYRK1A-TGF-β signaling axis determines sensitivity to OXPHOS inhibition in hepatocellular carcinoma21
How structural interactions and receptor phosphorylation shape strigolactone signaling in rice21
Zonated Wnt/β-catenin signal-activated cardiomyocytes at the atrioventricular canal promote coronary vessel formation in zebrafish21
Gibberellin and cytokinin signaling antagonistically control female-germline cell specification in Arabidopsis21
Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex20
Adaptive mechanoproperties mediated by the formin FMN1 characterize glioblastoma fitness for invasion20
Decreased GATA3 levels cause changed mouse cutaneous innate lymphoid cell fate, facilitating hair follicle recycling20
Identifying FUS amyotrophic lateral sclerosis disease signatures in patient dermal fibroblasts20
Neuroblastoma differentiation in vivo excludes cranial tumors20
Epithelial aPKC deficiency leads to stem cell loss preceding metaplasia in colorectal cancer initiation20
Unlocking trophectoderm mysteries: In vivo and in vitro perspectives on human and mouse trophoblast fate induction20
Xyloglucan side chains enable polysaccharide secretion to the plant cell wall20
Beating the heat: Phase separation in plant stress granules20
Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection20
Cox7a1 controls skeletal muscle physiology and heart regeneration through complex IV dimerization20
Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease20
The evolutionarily ancient FOXA transcription factors shape the murine gut microbiome via control of epithelial glycosylation20
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