Developmental Cell

Papers
(The median citation count of Developmental Cell is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-12-01 to 2024-12-01.)
ArticleCitations
Thriving under Stress: How Plants Balance Growth and the Stress Response394
Lipid metabolism in cancer: New perspectives and emerging mechanisms302
ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation263
Distinct contributions of partial and full EMT to breast cancer malignancy230
Quality control of the mitochondrion222
Single-Cell Sequencing of Developing Human Gut Reveals Transcriptional Links to Childhood Crohn’s Disease207
A Single-Cell Transcriptomic Atlas of Human Skin Aging191
A single-cell analysis of the Arabidopsis vegetative shoot apex185
Surviving and thriving: How plants perceive and respond to temperature stress166
A single-cell Arabidopsis root atlas reveals developmental trajectories in wild-type and cell identity mutants164
Single-cell RNA sequencing of developing maize ears facilitates functional analysis and trait candidate gene discovery153
Niches that regulate stem cells and hematopoiesis in adult bone marrow152
Single-cell resolution of lineage trajectories in the Arabidopsis stomatal lineage and developing leaf147
Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies132
ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress131
Lipid metabolism and lipid signals in aging and longevity130
NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C124
Mechanical Adaptability of Tumor Cells in Metastasis124
Autophagy and organelle homeostasis in cancer119
Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy119
The single-cell stereo-seq reveals region-specific cell subtypes and transcriptome profiling in Arabidopsis leaves118
Epithelial plasticity, epithelial-mesenchymal transition, and the TGF-β family110
Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival99
Enhancer grammar in development, evolution, and disease: dependencies and interplay92
Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy91
Early human embryonic development: Blastocyst formation to gastrulation90
Tissue mechanics in stem cell fate, development, and cancer89
Diverse nitrogen signals activate convergent ROP2-TOR signaling in Arabidopsis89
Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells89
S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity88
A census of the lung: CellCards from LungMAP87
N6-methyladenosine modification of MALAT1 promotes metastasis via reshaping nuclear speckles86
Spatiotemporal mapping of gene expression landscapes and developmental trajectories during zebrafish embryogenesis86
Extracellular vesicles: Critical players during cell migration85
Mitochondrial-derived vesicles compensate for loss of LC3-mediated mitophagy84
High-resolution 3D spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae83
Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro83
Fibroblast dedifferentiation as a determinant of successful regeneration81
Physical properties of the cytoplasm modulate the rates of microtubule polymerization and depolymerization80
Single-cell analysis of human testis aging and correlation with elevated body mass index80
ER-phagy responses in yeast, plants, and mammalian cells and their crosstalk with UPR and ERAD79
Next-Generation Lineage Tracing and Fate Mapping to Interrogate Development77
Histone H3 lysine 4 trimethylation in sperm is transmitted to the embryo and associated with diet-induced phenotypes in the offspring76
The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells75
Durotaxis: The Hard Path from In Vitro to In Vivo73
A BIN2-GLK1 Signaling Module Integrates Brassinosteroid and Light Signaling to Repress Chloroplast Development in the Dark73
Aging-dependent regulatory cells emerge in subcutaneous fat to inhibit adipogenesis71
Robustness of epithelial sealing is an emerging property of local ERK feedback driven by cell elimination71
Actin-Membrane Release Initiates Cell Protrusions71
Inflammation of the Embryonic Choroid Plexus Barrier following Maternal Immune Activation70
Programmable Extracellular Vesicles for Macromolecule Delivery and Genome Modifications70
Mechanics of Development69
3D mesenchymal cell migration is driven by anterior cellular contraction that generates an extracellular matrix prestrain68
Liquid-liquid phase separation of RBGD2/4 is required for heat stress resistance in Arabidopsis67
Global and Site-Specific Effect of Phosphorylation on Protein Turnover67
A human breast atlas integrating single-cell proteomics and transcriptomics67
Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease67
ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression67
Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population66
Harnessing Mechanobiology for Tissue Engineering66
Excessive R-loops trigger an inflammatory cascade leading to increased HSPC production65
A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie–Wnt signaling axis in the liver64
VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites63
Subcellular coordination of plant cell wall synthesis62
The central moTOR of metabolism62
Global mapping of glycosylation pathways in human-derived cells61
Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage61
N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation60
Diverse Routes toward Early Somites in the Mouse Embryo60
α-tubulin tail modifications regulate microtubule stability through selective effector recruitment, not changes in intrinsic polymer dynamics60
A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase60
The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth59
ERK1/2 inhibition promotes robust myotube growth via CaMKII activation resulting in myoblast-to-myotube fusion59
Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation59
Reticulon-3 Promotes Endosome Maturation at ER Membrane Contact Sites59
Cholesterol transport between cellular membranes: A balancing act between interconnected lipid fluxes58
A unique macrophage subpopulation signals directly to progenitor cells to promote regenerative neurogenesis in the zebrafish spinal cord56
Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongation55
Single-cell transcriptome analysis reveals three sequential phases of gene expression during zebrafish sensory hair cell regeneration55
WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues55
The structure and spontaneous curvature of clathrin lattices at the plasma membrane54
The spatiotemporal dynamics of microglia across the human lifespan54
Diversity of developing peripheral glia revealed by single-cell RNA sequencing53
Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration52
LIMD1 phase separation contributes to cellular mechanics and durotaxis by regulating focal adhesion dynamics in response to force52
Membrane receptor-mediated mechano-transduction maintains cell integrity during pollen tube growth within the pistil52
Genetically variant human pluripotent stem cells selectively eliminate wild-type counterparts through YAP-mediated cell competition52
Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C51
Glucose starvation induces autophagy via ULK1-mediated activation of PIKfyve in an AMPK-dependent manner51
Temporal analyses of postnatal liver development and maturation by single-cell transcriptomics50
Compartmentalization of telomeres through DNA-scaffolded phase separation50
Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation49
RBPMS is an RNA-binding protein that mediates cardiomyocyte binucleation and cardiovascular development49
A switch in pdgfrb cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord49
Embryonic Stem Cell-Derived Extracellular Vesicles Maintain ESC Stemness by Activating FAK49
Localized EMT reprograms glial progenitors to promote spinal cord repair49
Spatial transcriptional mapping of the human nephrogenic program48
Genetic variation associated with condensate dysregulation in disease47
Lineage-Resolved Enhancer and Promoter Usage during a Time Course of Embryogenesis47
A Ca2+-sensor switch for tolerance to elevated salt stress in Arabidopsis46
Formation of polarized contractile interfaces by self-organized Toll-8/Cirl GPCR asymmetry45
iPSC-derived myelinoids to study myelin biology of humans45
GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis44
Heart regeneration: 20 years of progress and renewed optimism44
Cardiac proteomics reveals sex chromosome-dependent differences between males and females that arise prior to gonad formation44
Homology-directed repair protects the replicating genome from metabolic assaults43
Metabolic plasticity drives development during mammalian embryogenesis43
Messenger RNA 5′ NAD+ Capping Is a Dynamic Regulatory Epitranscriptome Mark That Is Required for Proper Response to Abscisic Acid in Arabidopsis43
Cell-specific cis-regulatory elements and mechanisms of non-coding genetic disease in human retina and retinal organoids43
A reflux-and-growth mechanism explains oscillatory patterning of lateral root branching sites43
Autophagy promotes cell survival by maintaining NAD levels42
Rheb-regulated mitochondrial pyruvate metabolism of Schwann cells linked to axon stability42
Beyond PROX1: transcriptional, epigenetic, and noncoding RNA regulation of lymphatic identity and function42
Oncogene-regulated release of extracellular vesicles42
Functional Diversification of SRSF Protein Kinase to Control Ubiquitin-Dependent Neurodevelopmental Signaling41
A multiscale analysis of early flower development in Arabidopsis provides an integrated view of molecular regulation and growth control41
Rewired glycosylation activity promotes scarless regeneration and functional recovery in spiny mice after complete spinal cord transection41
The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology41
Inositol Polyphosphate Multikinase Inhibits Liquid-Liquid Phase Separation of TFEB to Negatively Regulate Autophagy Activity41
Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineages40
Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration40
Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK40
Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging40
PDGF signaling inhibits mitophagy in glioblastoma stem cells through N-methyladenosine39
The myogenesis program drives clonal selection and drug resistance in rhabdomyosarcoma39
Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation39
Neuronal mitochondrial dynamics coordinate systemic mitochondrial morphology and stress response to confer pathogen resistance in C. elegans38
Coordinate regulation of the senescent state by selective autophagy38
Transit-Amplifying Cells Coordinate Changes in Intestinal Epithelial Cell-Type Composition38
Tyramine Acts Downstream of Neuronal XBP-1s to Coordinate Inter-tissue UPRER Activation and Behavior in C. elegans38
An essential role for the piRNA pathway in regulating the ribosomal RNA pool in C. elegans37
Identification of long-lived proteins in the mitochondria reveals increased stability of the electron transport chain37
Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice37
Proteostasis failure and mitochondrial dysfunction leads to aneuploidy-induced senescence37
Developmental landscape of human forebrain at a single-cell level identifies early waves of oligodendrogenesis37
FoxA-dependent demethylation of DNA initiates epigenetic memory of cellular identity37
Reprogrammed lipid metabolism protects inner nuclear membrane against unsaturated fat37
Plant glutamate receptors mediate a bet-hedging strategy between regeneration and defense37
Filopodium-derived vesicles produced by MIM enhance the migration of recipient cells37
Lipid metabolism in adaptation to extreme nutritional challenges36
Motor usage imprints microtubule stability along the shaft36
Molecular and spatial landmarks of early mouse skin development35
Mechanobiology of the Mitotic Spindle35
A potassium-sensing niche in Arabidopsis roots orchestrates signaling and adaptation responses to maintain nutrient homeostasis35
Human placental cytotrophoblast epigenome dynamics over gestation and alterations in placental disease35
Oxidative stress pathogenically remodels the cardiac myocyte cytoskeleton via structural alterations to the microtubule lattice35
Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state35
Gene regulatory networks shape developmental plasticity of root cell types under water extremes in rice35
Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration35
Tumor-induced disruption of the blood-brain barrier promotes host death35
Mechanical feedback defines organizing centers to drive digit emergence34
Spatiotemporal control of ERK pulse frequency coordinates fate decisions during mammary acinar morphogenesis34
Maintaining the structural and functional homeostasis of the plant endoplasmic reticulum34
Paramecium Polycomb repressive complex 2 physically interacts with the small RNA-binding PIWI protein to repress transposable elements34
Single-cell analysis of shared signatures and transcriptional diversity during zebrafish development34
Progenitor-like characteristics in a subgroup of UCP1+ cells within white adipose tissue33
Adaptable P body physical states differentially regulate bicoid mRNA storage during early Drosophila development33
Vangl2 limits chaperone-mediated autophagy to balance osteogenic differentiation in mesenchymal stem cells32
A subpopulation of embryonic microglia respond to maternal stress and influence nearby neural progenitors32
Homeostatic Regulation of ROS-Triggered Hippo-Yki Pathway via Autophagic Clearance of Ref(2)P/p62 in the Drosophila Intestine32
Cell Junction Mechanics beyond the Bounds of Adhesion and Tension32
Ubiquitin-dependent remodeling of the actin cytoskeleton drives cell fusion32
Deceleration of the cell cycle underpins a switch from proliferative to terminal divisions in plant stomatal lineage32
Opposing motors provide mechanical and functional robustness in the human spindle32
Adaptive differentiation promotes intestinal villus recovery31
Genome-wide analysis of pseudogenes reveals HBBP1’s human-specific essentiality in erythropoiesis and implication in β-thalassemia31
Acute brain vascular regeneration occurs via lymphatic transdifferentiation31
Mechanistic connections between mitochondrial biology and regulated cell death31
Rheb mediates neuronal-activity-induced mitochondrial energetics through mTORC1-independent PDH activation31
External Mechanical Cues Reveal a Katanin-Independent Mechanism behind Auxin-Mediated Tissue Bending in Plants31
3D biomimetic platform reveals the first interactions of the embryo and the maternal blood vessels31
Cytoplasm’s Got Moves31
Localized glucose import, glycolytic processing, and mitochondria generate a focused ATP burst to power basement-membrane invasion31
De novo endocytic clathrin coats develop curvature at early stages of their formation31
Establishment of the vertebrate body plan: Rethinking gastrulation through stem cell models of early embryogenesis31
A HD-ZIP transcription factor specifies fates of multicellular trichomes via dosage-dependent mechanisms in tomato30
Root twisting drives halotropism via stress-induced microtubule reorientation30
PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay30
Mechanical conflict caused by a cell-wall-loosening enzyme activates de novo shoot regeneration30
Znhit1 controls meiotic initiation in male germ cells by coordinating with Stra8 to activate meiotic gene expression30
RNA N6-methyladenosine modification promotes auxin biosynthesis required for male meiosis in rice30
Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes29
De novo generation of macrophage from placenta-derived hemogenic endothelium29
Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD29
Mechanical competition triggered by innate immune signaling drives the collective extrusion of bacterially infected epithelial cells29
A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies29
The role of senescence in cellular plasticity: Lessons from regeneration and development and implications for age-related diseases29
piRNAs initiate transcriptional silencing of spermatogenic genes during C. elegans germline development29
Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfβ-Id2 axis, for tissue regeneration29
Transgenerational inheritance of sexual attractiveness via small RNAs enhances evolvability in C. elegans28
Developmental angiocrine diversification of endothelial cells for organotypic regeneration28
Mechanistic insights into actin force generation during vesicle formation from cryo-electron tomography28
Proliferative stem cells maintain quiescence of their niche by secreting the Activin inhibitor Follistatin28
Notch signaling induces either apoptosis or cell fate change in multiciliated cells during mucociliary tissue remodeling28
Tumor-derived MMPs regulate cachexia in a Drosophila cancer model28
Sulfenylation of ENOLASE2 facilitates H2O2-conferred freezing tolerance in Arabidopsis28
Pluripotency factors are repurposed to shape the epigenomic landscape of neural crest cells28
PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport28
Rapid and efficient degradation of endogenous proteins in vivo identifies stage-specific roles of RNA Pol II pausing in mammalian development27
RAB19 Directs Cortical Remodeling and Membrane Growth for Primary Ciliogenesis27
A G protein-coupled receptor-like module regulates cellulose synthase secretion from the endomembrane system in Arabidopsis27
Extracellular mechanical forces drive endocardial cell volume decrease during zebrafish cardiac valve morphogenesis27
A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids26
A two-tier junctional mechanism drives simultaneous tissue folding and extension26
H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity26
Sonic hedgehog is not a limb morphogen but acts as a trigger to specify all digits in mice26
Distinct classes of lagging chromosome underpin age-related oocyte aneuploidy in mouse26
RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness26
Reshaping of the tumor microenvironment by cellular senescence: An opportunity for senotherapies26
Proteolytic activation of Growth-blocking peptides triggers calcium responses through the GPCR Mthl10 during epithelial wound detection26
KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling26
Directed cell invasion and asymmetric adhesion drive tissue elongation and turning in C. elegans gonad morphogenesis25
Low-density-lipoprotein-receptor-related protein 1 mediates Notch pathway activation25
The miR-430 locus with extreme promoter density forms a transcription body during the minor wave of zygotic genome activation25
Rapid and robust optogenetic control of gene expression in Drosophila25
A single-cell transcriptomic inventory of murine smooth muscle cells25
SURF4-induced tubular ERGIC selectively expedites ER-to-Golgi transport25
Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients24
A metabolic daylength measurement system mediates winter photoperiodism in plants24
Dynamic Transcriptional Responses to Injury of Regenerative and Non-regenerative Cardiomyocytes Revealed by Single-Nucleus RNA Sequencing24
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility24
Regulation of ARGONAUTE10 Expression Enables Temporal and Spatial Precision in Axillary Meristem Initiation in Arabidopsis24
Monomethyl branched-chain fatty acid mediates amino acid sensing upstream of mTORC124
Germ cell differentiation requires Tdrd7-dependent chromatin and transcriptome reprogramming marked by germ plasm relocalization24
Autophagy Blockade Limits HER2+ Breast Cancer Tumorigenesis by Perturbing HER2 Trafficking and Promoting Release Via Small Extracellular Vesicles24
Partial EMT takes the lead in cancer metastasis24
Polyploid mitosis and depolyploidization promote chromosomal instability and tumor progression in a Notch-induced tumor model24
Regulation of reverse electron transfer at mitochondrial complex I by unconventional Notch action in cancer stem cells24
Lipolysis-derived linoleic acid drives beige fat progenitor cell proliferation23
Exocytosis by vesicle crumpling maintains apical membrane homeostasis during exocrine secretion23
Coupled oscillators coordinate collective germline growth23
Microenvironmental innate immune signaling and cell mechanical responses promote tumor growth23
Arp2/3-dependent mechanical control of morphogenetic robustness in an inherently challenging environment23
Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation23
Kinetochore life histories reveal an Aurora-B-dependent error correction mechanism in anaphase23
Inherited nuclear pore substructures template post-mitotic pore assembly23
YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth23
A gel-like condensation of Cidec generates lipid-permeable plates for lipid droplet fusion23
Filament-guided filament assembly provides structural memory of filament alignment during cytokinesis23
Sensing plasma membrane pore formation induces chemokine production in survivors of regulated necrosis23
Apical Relaxation during Mitotic Rounding Promotes Tension-Oriented Cell Division23
Endothelial and Leptin Receptor+ cells promote the maintenance of stem cells and hematopoiesis in early postnatal murine bone marrow23
Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle23
Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells23
Gasdermin D maintains bone mass by rewiring the endo-lysosomal pathway of osteoclastic bone resorption23
Cellular heterogeneity of human fallopian tubes in normal and hydrosalpinx disease states identified using scRNA-seq23
Formation and function of the meningeal arachnoid barrier around the developing mouse brain23
Separase cleaves the kinetochore protein Meikin at the meiosis I/II transition23
FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma22
Cochlear supporting cells require GAS2 for cytoskeletal architecture and hearing22
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