Developmental Cell

Papers
(The median citation count of Developmental Cell is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)
ArticleCitations
Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV-2 Receptor ACE2 in the Respiratory Tract312
Thriving under Stress: How Plants Balance Growth and the Stress Response270
ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation240
Phase Separation and Neurodegenerative Diseases: A Disturbance in the Force227
Lipid metabolism in cancer: New perspectives and emerging mechanisms199
Phase Separation in Membrane Biology: The Interplay between Membrane-Bound Organelles and Membraneless Condensates171
Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development164
Single-Cell Sequencing of Developing Human Gut Reveals Transcriptional Links to Childhood Crohn’s Disease157
Distinct contributions of partial and full EMT to breast cancer malignancy155
The Tubulin Code in Microtubule Dynamics and Information Encoding153
ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization149
Single-Cell RNA Sequencing of Human, Macaque, and Mouse Testes Uncovers Conserved and Divergent Features of Mammalian Spermatogenesis145
Quality control of the mitochondrion140
A single-cell analysis of the Arabidopsis vegetative shoot apex139
Dietary Lipids Induce Ferroptosis in Caenorhabditiselegans and Human Cancer Cells138
Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung137
A Single-Cell Transcriptomic Atlas of Human Skin Aging135
Hematopoietic Stem Cell Metabolism during Development and Aging123
Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex123
Single-cell RNA sequencing of developing maize ears facilitates functional analysis and trait candidate gene discovery121
CRISPR-Cas13d Induces Efficient mRNA Knockdown in Animal Embryos120
Single-cell resolution of lineage trajectories in the Arabidopsis stomatal lineage and developing leaf117
Single-Cell Transcriptomic Analyses of the Developing Meninges Reveal Meningeal Fibroblast Diversity and Function114
Cancer Cells Don’t Live Alone: Metabolic Communication within Tumor Microenvironments111
Niches that regulate stem cells and hematopoiesis in adult bone marrow110
Cellular Mechanisms and Regulation of Quiescence110
A Combinatorial MAP Code Dictates Polarized Microtubule Transport105
ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress104
In Vitro and In Vivo Development of the Human Airway at Single-Cell Resolution102
Surviving and thriving: How plants perceive and respond to temperature stress101
NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C99
A single-cell Arabidopsis root atlas reveals developmental trajectories in wild-type and cell identity mutants97
Microtubule Nucleation Properties of Single Human γTuRCs Explained by Their Cryo-EM Structure96
Metabolic Reprogramming Promotes Neural Crest Migration via Yap/Tead Signaling94
Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies94
Lipid metabolism and lipid signals in aging and longevity94
Of Cell Shapes and Motion: The Physical Basis of Animal Cell Migration93
Glycolysis-Independent Glucose Metabolism Distinguishes TE from ICM Fate during Mammalian Embryogenesis91
Mechanical Adaptability of Tumor Cells in Metastasis91
Mechanosensing through Direct Binding of Tensed F-Actin by LIM Domains90
Comprehensive Endogenous Tagging of Basement Membrane Components Reveals Dynamic Movement within the Matrix Scaffolding90
Intestinal Regeneration: Regulation by the Microenvironment89
The GSK3-like Kinase BIN2 Is a Molecular Switch between the Salt Stress Response and Growth Recovery in Arabidopsis thaliana85
The single-cell stereo-seq reveals region-specific cell subtypes and transcriptome profiling in Arabidopsis leaves85
Dynamic Transcriptional Responses to Injury of Regenerative and Non-regenerative Cardiomyocytes Revealed by Single-Nucleus RNA Sequencing84
A Dual Protein-mRNA Localization Screen Reveals Compartmentalized Translation and Widespread Co-translational RNA Targeting84
Emerging Roles for Phase Separation in Plants84
Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival84
OsNSUN2-Mediated 5-Methylcytosine mRNA Modification Enhances Rice Adaptation to High Temperature80
Gli1+ Periodontium Stem Cells Are Regulated by Osteocytes and Occlusal Force80
Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy80
Enhancer grammar in development, evolution, and disease: dependencies and interplay79
Epithelial plasticity, epithelial-mesenchymal transition, and the TGF-β family79
Integration of Hippo-YAP Signaling with Metabolism79
Chromatin Accessibility Dynamics and a Hierarchical Transcriptional Regulatory Network Structure for Plant Somatic Embryogenesis79
Differentiation of Human Intestinal Organoids with Endogenous Vascular Endothelial Cells78
Metabolites Regulate Cell Signaling and Growth via Covalent Modification of Proteins76
The Lysosome at the Intersection of Cellular Growth and Destruction75
Buckling of an Epithelium Growing under Spherical Confinement75
Liquid-Liquid Phase Separation in Neuronal Development and Synaptic Signaling75
Diverse nitrogen signals activate convergent ROP2-TOR signaling in Arabidopsis74
Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells74
S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity73
Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro73
Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy71
N6-methyladenosine modification of MALAT1 promotes metastasis via reshaping nuclear speckles71
ER-phagy responses in yeast, plants, and mammalian cells and their crosstalk with UPR and ERAD71
Tissue mechanics in stem cell fate, development, and cancer70
Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression69
Illuminating NAD+ Metabolism in Live Cells and In Vivo Using a Genetically Encoded Fluorescent Sensor69
Dek Modulates Global Intron Retention during Muscle Stem Cells Quiescence Exit68
Live Visualization of ERK Activity in the Mouse Blastocyst Reveals Lineage-Specific Signaling Dynamics67
Genetic Fate Mapping of Transient Cell Fate Reveals N-Cadherin Activity and Function in Tumor Metastasis67
Histone H3 lysine 4 trimethylation in sperm is transmitted to the embryo and associated with diet-induced phenotypes in the offspring66
Fibroblast dedifferentiation as a determinant of successful regeneration66
Mitochondrial-derived vesicles compensate for loss of LC3-mediated mitophagy65
Next-Generation Lineage Tracing and Fate Mapping to Interrogate Development65
Cell-Cycle-Dependent ERK Signaling Dynamics Direct Fate Specification in the Mammalian Preimplantation Embryo65
Robustness of epithelial sealing is an emerging property of local ERK feedback driven by cell elimination64
Oncogenic Signaling Alters Cell Shape and Mechanics to Facilitate Cell Division under Confinement64
A census of the lung: CellCards from LungMAP63
Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria63
The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells63
Early human embryonic development: Blastocyst formation to gastrulation62
Mechanical Coupling Coordinates the Co-elongation of Axial and Paraxial Tissues in Avian Embryos62
Autophagy and organelle homeostasis in cancer62
Extracellular vesicles: Critical players during cell migration60
Durotaxis: The Hard Path from In Vitro to In Vivo60
Single-Cell RNA Sequencing of the Cynomolgus Macaque Testis Reveals Conserved Transcriptional Profiles during Mammalian Spermatogenesis60
An Excitable Ras/PI3K/ERK Signaling Network Controls Migration and Oncogenic Transformation in Epithelial Cells60
Actin-Membrane Release Initiates Cell Protrusions59
Mechanics of Development58
Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease58
A Self-Organized PLT/Auxin/ARR-B Network Controls the Dynamics of Root Zonation Development in Arabidopsis thaliana57
A BIN2-GLK1 Signaling Module Integrates Brassinosteroid and Light Signaling to Repress Chloroplast Development in the Dark57
Exaptive Evolution of Target of Rapamycin Signaling in Multicellular Eukaryotes57
Global and Site-Specific Effect of Phosphorylation on Protein Turnover57
3D mesenchymal cell migration is driven by anterior cellular contraction that generates an extracellular matrix prestrain57
Dysfunction of Hair Follicle Mesenchymal Progenitors Contributes to Age-Associated Hair Loss56
Excessive R-loops trigger an inflammatory cascade leading to increased HSPC production56
Potently Cytotoxic Natural Killer Cells Initially Emerge from Erythro-Myeloid Progenitors during Mammalian Development56
Lamin B2 Levels Regulate Polyploidization of Cardiomyocyte Nuclei and Myocardial Regeneration55
Programmable Extracellular Vesicles for Macromolecule Delivery and Genome Modifications55
High-resolution 3D spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae55
Inflammation of the Embryonic Choroid Plexus Barrier following Maternal Immune Activation55
ESCRT-III/Vps4 Controls Heterochromatin-Nuclear Envelope Attachments55
A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie–Wnt signaling axis in the liver54
Spatiotemporal mapping of gene expression landscapes and developmental trajectories during zebrafish embryogenesis54
Harnessing Mechanobiology for Tissue Engineering53
α-tubulin tail modifications regulate microtubule stability through selective effector recruitment, not changes in intrinsic polymer dynamics52
Metabolic Communication and Healthy Aging: Where Should We Focus Our Energy?51
Phase Separation in Germ Cells and Development51
Aging-dependent regulatory cells emerge in subcutaneous fat to inhibit adipogenesis50
CDK-Regulated Phase Separation Seeded by Histone Genes Ensures Precise Growth and Function of Histone Locus Bodies50
Subcellular mRNA Localization Regulates Ribosome Biogenesis in Migrating Cells49
A human breast atlas integrating single-cell proteomics and transcriptomics49
Transnitrosylation Mediated by the Non-canonical Catalase ROG1 Regulates Nitric Oxide Signaling in Plants49
The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth48
N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation48
Glutamine Metabolism Controls Chondrocyte Identity and Function47
Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongation47
Functional Heterogeneity within the Developing Zebrafish Epicardium47
Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population47
Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors47
Diverse Routes toward Early Somites in the Mouse Embryo46
Membrane receptor-mediated mechano-transduction maintains cell integrity during pollen tube growth within the pistil46
Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production46
Single-cell analysis of human testis aging and correlation with elevated body mass index46
Lineage-Resolved Enhancer and Promoter Usage during a Time Course of Embryogenesis46
Modulation of the Promoter Activation Rate Dictates the Transcriptional Response to Graded BMP Signaling Levels in the Drosophila Embryo46
Hyperinsulinemia Drives Epithelial Tumorigenesis by Abrogating Cell Competition46
Basement Membrane Regulates Fibronectin Organization Using Sliding Focal Adhesions Driven by a Contractile Winch46
WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues46
Tether Me, Tether Me Not—Dynamic Organelle Contact Sites in Metabolic Rewiring46
Caveolae Control Contractile Tension for Epithelia to Eliminate Tumor Cells46
VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites45
Global mapping of glycosylation pathways in human-derived cells45
The Dynein Adaptor RILP Controls Neuronal Autophagosome Biogenesis, Transport, and Clearance45
Liquid-liquid phase separation of RBGD2/4 is required for heat stress resistance in Arabidopsis45
Metabolic Cellular Communications: Feedback Mechanisms between Membrane Lipid Homeostasis and Plant Development45
DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma45
A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase44
Reticulon-3 Promotes Endosome Maturation at ER Membrane Contact Sites44
A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle44
Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation44
ERK1/2 inhibition promotes robust myotube growth via CaMKII activation resulting in myoblast-to-myotube fusion44
Selective Lysosome Membrane Turnover Is Induced by Nutrient Starvation44
The structure and spontaneous curvature of clathrin lattices at the plasma membrane44
Hedgehog Pathway Activation Requires Coreceptor-Catalyzed, Lipid-Dependent Relay of the Sonic Hedgehog Ligand44
Subcellular coordination of plant cell wall synthesis43
Physical properties of the cytoplasm modulate the rates of microtubule polymerization and depolymerization43
Embryonic Stem Cell-Derived Extracellular Vesicles Maintain ESC Stemness by Activating FAK42
TRAIL Receptors Serve as Stress-Associated Molecular Patterns to Promote ER-Stress-Induced Inflammation42
Frizzled-Dependent Planar Cell Polarity without Secreted Wnt Ligands42
Exploring the Influence of Cell Metabolism on Cell Fate through Protein Post-translational Modifications42
A Weak Link with Actin Organizes Tight Junctions to Control Epithelial Permeability42
The central moTOR of metabolism42
Spatial transcriptional mapping of the human nephrogenic program41
Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C41
A unique macrophage subpopulation signals directly to progenitor cells to promote regenerative neurogenesis in the zebrafish spinal cord41
Distinct Cation Gradients Power Cholesterol Transport at Different Key Points in the Hedgehog Signaling Pathway40
Determinants of Endoplasmic Reticulum-to-Lipid Droplet Protein Targeting40
A switch in pdgfrb cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord40
Genetic variation associated with condensate dysregulation in disease40
ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression40
Cholesterol transport between cellular membranes: A balancing act between interconnected lipid fluxes40
Tissue-Scale Mechanical Coupling Reduces Morphogenetic Noise to Ensure Precision during Epithelial Folding40
Formation of polarized contractile interfaces by self-organized Toll-8/Cirl GPCR asymmetry39
Smooth Muscle Differentiation Is Essential for Airway Size, Tracheal Cartilage Segmentation, but Dispensable for Epithelial Branching39
The Perinuclear ER Scales Nuclear Size Independently of Cell Size in Early Embryos39
Localized EMT reprograms glial progenitors to promote spinal cord repair38
Messenger RNA 5′ NAD+ Capping Is a Dynamic Regulatory Epitranscriptome Mark That Is Required for Proper Response to Abscisic Acid in Arabidopsis38
Homology-directed repair protects the replicating genome from metabolic assaults38
Beyond PROX1: transcriptional, epigenetic, and noncoding RNA regulation of lymphatic identity and function38
Diversity of developing peripheral glia revealed by single-cell RNA sequencing38
Sphingosine 1-Phosphate Receptor Signaling Establishes AP-1 Gradients to Allow for Retinal Endothelial Cell Specialization38
A multiscale analysis of early flower development in Arabidopsis provides an integrated view of molecular regulation and growth control37
Xist Repeats A and B Account for Two Distinct Phases of X Inactivation Establishment37
Oncogene-regulated release of extracellular vesicles37
Genetically variant human pluripotent stem cells selectively eliminate wild-type counterparts through YAP-mediated cell competition37
RBPMS is an RNA-binding protein that mediates cardiomyocyte binucleation and cardiovascular development37
Rapid Dynamics of Signal-Dependent Transcriptional Repression by Capicua37
Biomolecular Condensates and Gene Activation in Development and Disease37
Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model37
Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates36
Cell-specific cis-regulatory elements and mechanisms of non-coding genetic disease in human retina and retinal organoids36
WAPL-Dependent Repair of Damaged DNA Replication Forks Underlies Oncogene-Induced Loss of Sister Chromatid Cohesion36
Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration36
A Specialized Niche in the Pancreatic Microenvironment Promotes Endocrine Differentiation36
LIMD1 phase separation contributes to cellular mechanics and durotaxis by regulating focal adhesion dynamics in response to force36
Functional Diversification of SRSF Protein Kinase to Control Ubiquitin-Dependent Neurodevelopmental Signaling36
ASK1-Mediated Phosphorylation Blocks HDAC6 Ubiquitination and Degradation to Drive the Disassembly of Photoreceptor Connecting Cilia36
Glucose starvation induces autophagy via ULK1-mediated activation of PIKfyve in an AMPK-dependent manner36
Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage35
A reflux-and-growth mechanism explains oscillatory patterning of lateral root branching sites35
Inositol Polyphosphate Multikinase Inhibits Liquid-Liquid Phase Separation of TFEB to Negatively Regulate Autophagy Activity35
Combinatorial Action of Temporally Segregated Transcription Factors35
Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation35
Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development35
Reprogramming Axial Level Identity to Rescue Neural-Crest-Related Congenital Heart Defects35
Rapid Homeostatic Turnover of Embryonic ECM during Tissue Morphogenesis35
Cardiac proteomics reveals sex chromosome-dependent differences between males and females that arise prior to gonad formation35
Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration35
Compartmentalization of telomeres through DNA-scaffolded phase separation35
Scaling a Dpp Morphogen Gradient through Feedback Control of Receptors and Co-receptors34
Reprogrammed lipid metabolism protects inner nuclear membrane against unsaturated fat33
iPSC-derived myelinoids to study myelin biology of humans33
Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK33
Peroxisome Elevation Induces Stem Cell Differentiation and Intestinal Epithelial Repair33
Single-cell transcriptome analysis reveals three sequential phases of gene expression during zebrafish sensory hair cell regeneration32
Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineages32
The spatiotemporal dynamics of microglia across the human lifespan32
HLH-30/TFEB Is a Master Regulator of Reproductive Quiescence32
Endolysosomal Targeting of Mitochondria Is Integral to BAX-Mediated Mitochondrial Permeabilization during Apoptosis Signaling31
Aberrant Expression of a Non-muscle RBFOX2 Isoform Triggers Cardiac Conduction Defects in Myotonic Dystrophy31
Autophagy promotes cell survival by maintaining NAD levels31
Phase Separation—A Physical Mechanism for Organizing Information and Biochemical Reactions31
An essential role for the piRNA pathway in regulating the ribosomal RNA pool in C. elegans31
Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging31
A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy30
A Ca2+-sensor switch for tolerance to elevated salt stress in Arabidopsis30
Proteostasis failure and mitochondrial dysfunction leads to aneuploidy-induced senescence30
Filopodium-derived vesicles produced by MIM enhance the migration of recipient cells30
Abscission Couples Cell Division to Embryonic Stem Cell Fate30
Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration29
Temporal analyses of postnatal liver development and maturation by single-cell transcriptomics29
FoxA-dependent demethylation of DNA initiates epigenetic memory of cellular identity29
Mechanobiology of the Mitotic Spindle29
A potassium-sensing niche in Arabidopsis roots orchestrates signaling and adaptation responses to maintain nutrient homeostasis29
Human placental cytotrophoblast epigenome dynamics over gestation and alterations in placental disease28
DNA Helicase Mph1FANCM Ensures Meiotic Recombination between Parental Chromosomes by Dissociating Precocious Displacement Loops28
Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice28
Tumor-induced disruption of the blood-brain barrier promotes host death28
Metabolic plasticity drives development during mammalian embryogenesis28
Motor usage imprints microtubule stability along the shaft28
Plant glutamate receptors mediate a bet-hedging strategy between regeneration and defense28
Neuronal mitochondrial dynamics coordinate systemic mitochondrial morphology and stress response to confer pathogen resistance in C. elegans28
Cell Junction Mechanics beyond the Bounds of Adhesion and Tension28
Coordinate regulation of the senescent state by selective autophagy28
External Mechanical Cues Reveal a Katanin-Independent Mechanism behind Auxin-Mediated Tissue Bending in Plants28
Maintaining the structural and functional homeostasis of the plant endoplasmic reticulum27
Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation27
The Mitotic Crosslinking Protein PRC1 Acts Like a Mechanical Dashpot to Resist Microtubule Sliding27
Less Is More: Rare Pulmonary Neuroendocrine Cells Function as Critical Sensors in Lung27
A subpopulation of embryonic microglia respond to maternal stress and influence nearby neural progenitors27
PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay27
Cytoplasm’s Got Moves27
Opposing motors provide mechanical and functional robustness in the human spindle27
Long-Range Optogenetic Control of Axon Guidance Overcomes Developmental Boundaries and Defects27
Paramecium Polycomb repressive complex 2 physically interacts with the small RNA-binding PIWI protein to repress transposable elements27
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